TreeWAS – Variant ID: rs523340

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O46.9 Antepartum haemorrhage, unspecified	0.000	0.969	0.031
R00.2 Palpitations	0.027	0.973	0.000
I08.0 Disorders of both mitral and aortic valves	0.013	0.987	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.012	0.988	0.000
N80.9 Endometriosis, unspecified	0.011	0.989	0.000
I08 Multiple valve diseases	0.011	0.989	0.000
G57.6 Lesion of plantar nerve	0.011	0.989	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.990	0.010
I08.2 Disorders of both aortic and tricuspid valves	0.009	0.991	0.000
I08.9 Multiple valve disease, unspecified	0.009	0.991	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.993	0.007
I08.8 Other multiple valve diseases	0.007	0.993	0.000
I05-I09 Chronic rheumatic heart diseases	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.994	0.006
M50.1 Cervical disk disorder with radiculopathy	0.006	0.994	0.000
B37.0 Candidal stomatitis	0.006	0.994	0.000
I05 Rheumatic mitral valve diseases	0.006	0.994	0.000
O46.8 Other antepartum haemorrhage	0.000	0.994	0.005
I05.9 Mitral valve disease, unspecified	0.005	0.995	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.005	0.995	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.005	0.995	0.000
I05.2 Mitral stenosis with insufficiency	0.005	0.995	0.000
I06 Rheumatic aortic valve diseases	0.005	0.995	0.000
M50 Cervical disk disorders	0.005	0.995	0.000
E21.0 Primary hyperparathyroidism	0.000	0.995	0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.995	0.005
R00 Abnormalities of heart beat	0.005	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.005	0.995	0.000
I09 Other rheumatic heart diseases	0.005	0.995	0.000
I05.1 Rheumatic mitral insufficiency	0.004	0.995	0.000
I73.9 Peripheral vascular disease, unspecified	0.005	0.995	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.004	0.996	0.000
M50.3 Other cervical disk degeneration	0.004	0.996	0.000
I05.8 Other mitral valve diseases	0.004	0.996	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
W19.2 School, other institution and public administrative area	0.004	0.996	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.996	0.004
N80.3 Endometriosis of pelvic peritoneum	0.004	0.996	0.000
I05.0 Mitral stenosis	0.004	0.996	0.000
M19.0 Primary arthrosis of other joints	0.004	0.996	0.000
M50.9 Cervical disk disorder, unspecified	0.004	0.996	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.004	0.996	0.000
G57 Mononeuropathies of lower limb	0.004	0.996	0.000
M50.2 Other cervical disk displacement	0.004	0.996	0.000
M50.8 Other cervical disk disorders	0.004	0.996	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.996	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.996	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.996	0.000
I06.1 Rheumatic aortic insufficiency	0.004	0.996	0.000
I06.0 Rheumatic aortic stenosis	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.004	0.996	0.000
N80 Endometriosis	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.996	0.004
E21.4 Other specified disorders of parathyroid gland	0.000	0.996	0.004
E21.2 Other hyperparathyroidism	0.000	0.996	0.004
M19.01 Primary arthrosis of other joints (Shoulder region)	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.003	0.996	0.000
I07.8 Other tricuspid valve diseases	0.003	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.003	0.996	0.000
I07.0 Tricuspid stenosis	0.003	0.996	0.000
I09.8 Other specified rheumatic heart diseases	0.003	0.996	0.000
I09.2 Chronic rheumatic pericarditis	0.003	0.996	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.003	0.996	0.000
I09.0 Rheumatic myocarditis	0.003	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.003	0.996	0.000
I07.1 Tricuspid insufficiency	0.003	0.996	0.000
G57.3 Lesion of lateral popliteal nerve	0.003	0.996	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.003	0.997	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.003	0.997	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.003	0.997	0.000
N80.8 Other endometriosis	0.003	0.997	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
G57.9 Mononeuropathy of lower limb, unspecified	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
N80.6 Endometriosis in cutaneous scar	0.003	0.997	0.000
M19.08 Primary arthrosis of other joints (Other)	0.003	0.997	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.003	0.997	0.000
I77.1 Stricture of artery	0.003	0.997	0.000
G57.4 Lesion of medial popliteal nerve	0.003	0.997	0.000
G57.2 Lesion of femoral nerve	0.003	0.997	0.000
G57.0 Lesion of sciatic nerve	0.003	0.997	0.000
G57.5 Tarsal tunnel syndrome	0.003	0.997	0.000
I77.3 Arterial fibromuscular dysplasia	0.003	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.003	0.997	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.003	0.997	0.000
Z97.4 Presence of external hearing-aid	0.003	0.997	0.000
H26.4 After-cataract	0.000	0.997	0.003
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
C01 Malignant neoplasm of base of tongue	0.003	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
N80.5 Endometriosis of intestine	0.002	0.997	0.000
R00.0 Tachycardia, unspecified	0.003	0.997	0.000
G57.1 Meralgia paraesthetica	0.002	0.997	0.000
H91.8 Other specified hearing loss	0.003	0.997	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.997	0.002
I77.5 Necrosis of artery	0.002	0.997	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.997	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
N80.2 Endometriosis of Fallopian tube	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
N87.1 Moderate cervical dysplasia	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
J30.1 Allergic rhinitis due to pollen	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
I31 Other diseases of pericardium	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I73 Other peripheral vascular diseases	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
I31.1 Chronic constrictive pericarditis	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.998	0.000
K12.0 Recurrent oral aphthae	0.002	0.998	0.000
N80.1 Endometriosis of ovary	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
H05.8 Other disorders of orbit	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
G57.8 Other mononeuropathies of lower limb	0.001	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
I31.8 Other specified diseases of pericardium	0.002	0.998	0.000
I31.2 Haemopericardium, not elsewhere classified	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.002	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.000	0.998	0.002
U88 Agent resistant to multiple antibiotics	0.000	0.998	0.002
M45.X9 Ankylosing spondylitis (Site unspecified)	0.002	0.998	0.000
B37.3 Candidiasis of vulva and vagina	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
K61.1 Rectal abscess	0.002	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.002	0.998	0.000
C14.0 Pharynx, unspecified	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.002	0.998	0.000
C00 Malignant neoplasm of lip	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.001	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.001	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.001	0.998	0.000
C00.0 External upper lip	0.001	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
C03 Malignant neoplasm of gum	0.001	0.998	0.000
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.998	0.001
U83 Resistance to other antibiotics	0.000	0.998	0.001
U82 Resistance to betalactam antibiotics	0.000	0.998	0.001
U85 Resistance to antineoplastic drugs	0.000	0.998	0.001
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.001	0.998	0.000
N60.0 Solitary cyst of breast	0.000	0.998	0.002
C11 Malignant neoplasm of nasopharynx	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.001
C05 Malignant neoplasm of palate	0.001	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
M45 Ankylosing spondylitis	0.002	0.998	0.000
H92.2 Otorrhagia	0.001	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.001	0.998	0.000
C13 Malignant neoplasm of hypopharynx	0.001	0.998	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.001	0.998	0.000
C04 Malignant neoplasm of floor of mouth	0.001	0.998	0.000
Z97 Presence of other devices	0.002	0.998	0.000
C03.1 Lower gum	0.001	0.998	0.000
N76.4 Abscess of vulva	0.001	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.001
K12 Stomatitis and related lesions	0.002	0.998	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.001	0.998	0.000
C14.2 Waldeyer's ring	0.001	0.998	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.001	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
Q76.1 Klippel-Feil syndrome	0.001	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.001	0.998	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
C09.9 Tonsil, unspecified	0.001	0.999	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
C00.9 Lip, unspecified	0.001	0.999	0.000
C00.8 Overlapping lesion of lip	0.001	0.999	0.000
C00.6 Commissure of lip	0.001	0.999	0.000
C00.5 Lip, unspecified, inner aspect	0.001	0.999	0.000
C00.4 Lower lip, inner aspect	0.001	0.999	0.000
C00.3 Upper lip, inner aspect	0.001	0.999	0.000
C00.2 External lip, unspecified	0.001	0.999	0.000
C00.1 External lower lip	0.001	0.999	0.000
C11.9 Nasopharynx, unspecified	0.001	0.999	0.000
Z97.3 Presence of spectacles and contact lenses	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
C06.2 Retromolar area	0.001	0.999	0.000
C06.0 Cheek mucosa	0.001	0.999	0.000
I67.1 Cerebral aneurysm, nonruptured	0.001	0.999	0.000
C05.1 Soft palate	0.001	0.999	0.000
L85.8 Other specified epidermal thickening	0.000	0.999	0.001
M81.2 Osteoporosis of disuse	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.999	0.001
U82.8 Resistance to other betalactam antibiotics	0.000	0.999	0.001
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.999	0.001
U82.1 Resistance to methicillin	0.000	0.999	0.001
U82.0 Resistance to penicillin	0.000	0.999	0.001
U83.9 Resistance to unspecified antibiotic	0.000	0.999	0.001
U83.8 Resistance to other single specified antibiotic	0.000	0.999	0.001
U83.7 Resistance to multiple antibiotics	0.000	0.999	0.001
U83.2 Resistance to quinolones	0.000	0.999	0.001
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.999	0.001
U83.0 Resistance to vancomycin	0.000	0.999	0.001
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.999	0.001
U84.8 Resistance to other specified antimicrobial drug	0.000	0.999	0.001
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.999	0.001
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.999	0.001
U84.2 Resistance to antiviral drug(s)	0.000	0.999	0.001
U84.1 Resistance to antifungal drug(s)	0.000	0.999	0.001
U84.0 Resistance to antiparasitic drug(s)	0.000	0.999	0.001
Q66 Congenital deformities of feet	0.001	0.999	0.000
C03.9 Gum, unspecified	0.001	0.999	0.000
C03.0 Upper gum	0.001	0.999	0.000
C06.9 Mouth, unspecified	0.001	0.999	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.001	0.999	0.000
C06.1 Vestibule of mouth	0.001	0.999	0.000
C09.8 Overlapping lesion of tonsil	0.001	0.999	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.001	0.999	0.000
C09.0 Tonsillar fossa	0.001	0.999	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.001	0.999	0.000
K12.3 Oral mucositis (ulcerative)	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
C05.9 Palate, unspecified	0.001	0.999	0.000
C05.8 Overlapping lesion of palate	0.001	0.999	0.000
C05.2 Uvula	0.001	0.999	0.000
C05.0 Hard palate	0.001	0.999	0.000
C11.8 Overlapping lesion of nasopharynx	0.001	0.999	0.000
C11.3 Anterior wall of nasopharynx	0.001	0.999	0.000
C11.2 Lateral wall of nasopharynx	0.001	0.999	0.000
C11.1 Posterior wall of nasopharynx	0.001	0.999	0.000
C11.0 Superior wall of nasopharynx	0.001	0.999	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.999	0.000
W19.6 Industrial and construction area	0.001	0.999	0.000
H05.0 Acute inflammation of orbit	0.001	0.999	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.001	0.999	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.001	0.999	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.001	0.999	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.001	0.999	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.001	0.999	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.001	0.999	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.001	0.999	0.000
N80.0 Endometriosis of uterus	0.001	0.999	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.999	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.999	0.000
Q76.7 Congenital malformation of sternum	0.001	0.999	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.999	0.000
Q76.5 Cervical rib	0.001	0.999	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.999	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.999	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.999	0.001
Y52.1 Calcium-channel blockers	0.001	0.999	0.000
I78 Diseases of capillaries	0.001	0.999	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.999	0.001
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
C04.8 Overlapping lesion of floor of mouth	0.001	0.999	0.000
C04.1 Lateral floor of mouth	0.001	0.999	0.000
C04.0 Anterior floor of mouth	0.001	0.999	0.000
C08.9 Major salivary gland, unspecified	0.001	0.999	0.000
C08.8 Overlapping lesion of major salivary glands	0.001	0.999	0.000
C08.1 Sublingual gland	0.001	0.999	0.000
C08.0 Submandibular gland	0.001	0.999	0.000
C13.9 Hypopharynx, unspecified	0.001	0.999	0.000
C13.8 Overlapping lesion of hypopharynx	0.001	0.999	0.000
C13.2 Posterior wall of hypopharynx	0.001	0.999	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.001	0.999	0.000
C13.0 Postcricoid region	0.001	0.999	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.001	0.999	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
U80.1 Methicillin resistant agent	0.000	0.999	0.001
V89.9 Person injured in unspecified vehicle accident	0.001	0.999	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.001	0.999	0.000
C04.9 Floor of mouth, unspecified	0.001	0.999	0.000
C10.8 Overlapping lesion of oropharynx	0.001	0.999	0.000
C10.4 Branchial cleft	0.001	0.999	0.000
C10.3 Posterior wall of oropharynx	0.001	0.999	0.000
C10.2 Lateral wall of oropharynx	0.001	0.999	0.000
C10.1 Anterior surface of epiglottis	0.001	0.999	0.000
C10.0 Vallecula	0.001	0.999	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
C07 Malignant neoplasm of parotid gland	0.001	0.999	0.000
Y52 Agents primarily affecting the cardiovascular system	0.001	0.999	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.999	0.001
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.001	0.999	0.000
B37 Candidiasis	0.001	0.999	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.999	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.001	0.999	0.000
H93.1 Tinnitus	0.001	0.999	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.001	0.999	0.000
M83.8 Other adult osteomalacia	0.001	0.999	0.000
S62.7 Multiple fractures of fingers	0.001	0.999	0.000
H91 Other hearing loss	0.001	0.999	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.001	0.999	0.000
M81.28 Osteoporosis of disuse (Other)	0.001	0.999	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.001	0.999	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.001	0.999	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.001	0.999	0.000
M81.24 Osteoporosis of disuse (Hand)	0.001	0.999	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.001	0.999	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.001	0.999	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
C10.9 Oropharynx, unspecified	0.001	0.999	0.000
C18.0 Caecum	0.000	0.999	0.001
C02 Malignant neoplasm of other and unspecified parts of tongue	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.999	0.001
D22.2 Melanocytic naevi of ear and external auricular canal	0.001	0.999	0.000
N60.2 Fibroadenosis of breast	0.000	0.999	0.001
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.2 Metatarsus varus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
S06.3 Focal brain injury	0.000	0.999	0.001
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.999	0.001
B37.7 Candidal septicaemia	0.001	0.999	0.000
I78.9 Disease of capillaries, unspecified	0.001	0.999	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.999	0.000
M81 Osteoporosis without pathological fracture	0.001	0.999	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.999	0.000
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
I78.1 Naevus, nonneoplastic	0.001	0.999	0.000
K61.3 Ischiorectal abscess	0.001	0.999	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
B37.2 Candidiasis of skin and nail	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.000	0.999	0.001
S72.0 Fracture of neck of femur	0.000	0.999	0.001
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
Y52.7 Peripheral vasodilators	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
Q65 Congenital deformities of hip	0.001	0.999	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.999	0.001
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.999	0.001
B37.6 Candidal endocarditis	0.001	0.999	0.000
B37.5 Candidal meningitis	0.001	0.999	0.000
C02.4 Lingual tonsil	0.001	0.999	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.999	0.000
H91.3 Deaf mutism, not elsewhere classified	0.001	0.999	0.000
H91.2 Sudden idiopathic hearing loss	0.001	0.999	0.000
H91.0 Ototoxic hearing loss	0.001	0.999	0.000
K75.0 Abscess of liver	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
H93 Other disorders of ear, not elsewhere classified	0.001	0.999	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.88 Other adult osteomalacia (Other)	0.001	0.999	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.001	0.999	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.84 Other adult osteomalacia (Hand)	0.001	0.999	0.000
M83.83 Other adult osteomalacia (Forearm)	0.001	0.999	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.001	0.999	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.001	0.999	0.000
C02.8 Overlapping lesion of tongue	0.001	0.999	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.001	0.999	0.000
C02.2 Ventral surface of tongue	0.001	0.999	0.000
C02.0 Dorsal surface of tongue	0.001	0.999	0.000
H05.9 Disorder of orbit, unspecified	0.001	0.999	0.000
K12.1 Other forms of stomatitis	0.001	0.999	0.000
K61.2 Anorectal abscess	0.001	0.999	0.000
H05 Disorders of orbit	0.001	0.999	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.999	0.001
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
N60.3 Fibrosclerosis of breast	0.000	0.999	0.001
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.999	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.999	0.001
C02.9 Tongue, unspecified	0.000	0.999	0.001
G62.8 Other specified polyneuropathies	0.000	0.999	0.001
I72.4 Aneurysm of artery of lower extremity	0.001	0.999	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.999	0.000
I79.1 Aortitis in diseases classified elsewhere	0.001	0.999	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.001	0.999	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
M81.8 Other osteoporosis	0.001	0.999	0.000
M81.6 Localised osteoporosis [Lequesne]	0.001	0.999	0.000
M81.5 Idiopathic osteoporosis	0.001	0.999	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.001	0.999	0.000
M81.1 Postoophorectomy osteoporosis	0.001	0.999	0.000
M81.0 Postmenopausal osteoporosis	0.001	0.999	0.000
S62.6 Fracture of other finger	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
I70 Atherosclerosis	0.001	0.999	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.999	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.999	0.001
S22.40 Multiple fractures of ribs (closed)	0.001	0.999	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.999	0.001
S72.31 Fracture of shaft of femur (open)	0.000	0.999	0.001
C02.1 Border of tongue	0.000	0.999	0.001
D11.0 Parotid gland	0.000	0.999	0.001
H93.3 Disorders of acoustic nerve	0.001	0.999	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
M83 Adult osteomalacia	0.001	0.999	0.000
Q78 Other osteochondrodysplasias	0.001	0.999	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.999	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.999	0.000
Q73 Reduction defects of unspecified limb	0.001	0.999	0.000
Q72 Reduction defects of lower limb	0.001	0.999	0.000
Q71 Reduction defects of upper limb	0.001	0.999	0.000
Q70 Syndactyly	0.001	0.999	0.000
Q69 Polydactyly	0.001	0.999	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.999	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.999	0.001
K58 Irritable bowel syndrome	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.999	0.001
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.001	0.999	0.000
H05.4 Enophthalmos	0.001	0.999	0.000
H05.3 Deformity of orbit	0.001	0.999	0.000
H05.1 Chronic inflammatory disorders of orbit	0.001	0.999	0.000
H91.1 Presbycusis	0.001	0.999	0.000
I70.9 Generalised and unspecified atherosclerosis	0.001	0.999	0.000
I70.8 Atherosclerosis of other arteries	0.001	0.999	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.999	0.001
M84.4 Pathological fracture, not elsewhere classified	0.001	0.999	0.000
K61 Abscess of anal and rectal regions	0.001	0.999	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations