TreeWAS – Variant ID: rs527430

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S72.00 Fracture of neck of femur (closed)	0.023	0.977	0.000
S72.0 Fracture of neck of femur	0.022	0.978	0.000
S72 Fracture of femur	0.021	0.979	0.000
S70-S79 Injuries to the hip and thigh	0.021	0.979	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.021	0.979	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.020	0.980	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.017	0.983	0.000
S70 Superficial injury of hip and thigh	0.017	0.983	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.017	0.983	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.017	0.983	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.017	0.983	0.000
S72.1 Pertrochanteric fracture	0.016	0.984	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.016	0.984	0.000
S72.01 Fracture of neck of femur (open)	0.016	0.984	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.016	0.984	0.000
S20-S29 Injuries to the thorax	0.016	0.984	0.000
S60-S69 Injuries to the wrist and hand	0.016	0.984	0.000
S72.9 Fracture of femur, part unspecified	0.015	0.984	0.000
S72.8 Fractures of other parts of femur	0.015	0.984	0.000
S72.7 Multiple fractures of femur	0.015	0.984	0.000
S72.4 Fracture of lower end of femur	0.015	0.984	0.000
S72.3 Fracture of shaft of femur	0.015	0.984	0.000
S72.2 Subtrochanteric fracture	0.015	0.984	0.000
S79 Other and unspecified injuries of hip and thigh	0.015	0.985	0.000
S78 Traumatic amputation of hip and thigh	0.015	0.985	0.000
S77 Crushing injury of hip and thigh	0.015	0.985	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.015	0.985	0.000
S75 Injury of blood vessels at hip and thigh level	0.015	0.985	0.000
S74 Injury of nerves at hip and thigh level	0.015	0.985	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.015	0.985	0.000
S71 Open wound of hip and thigh	0.015	0.985	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T43.2 Other and unspecified antidepressants	0.015	0.985	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.015	0.985	0.000
T79-T79 Certain early complications of trauma	0.015	0.985	0.000
T66-T78 Other and unspecified effects of external causes	0.015	0.985	0.000
T33-T35 Frostbite	0.015	0.985	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.015	0.985	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.015	0.985	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.015	0.985	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.015	0.985	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.015	0.985	0.000
T00-T07 Injuries involving multiple body regions	0.015	0.985	0.000
S90-S99 Injuries to the ankle and foot	0.015	0.985	0.000
S10-S19 Injuries to the neck	0.015	0.985	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.015	0.985	0.000
S40-S49 Injuries to the shoulder and upper arm	0.015	0.985	0.000
S80-S89 Injuries to the knee and lower leg	0.015	0.985	0.000
S00-S09 Injuries to the head	0.015	0.985	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.014	0.985	0.000
T51 Toxic effect of alcohol	0.014	0.985	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.014	0.986	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.014	0.986	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.014	0.986	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.014	0.986	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.014	0.986	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.014	0.986	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.014	0.986	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.014	0.986	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.014	0.986	0.000
T36 Poisoning by systemic antibiotics	0.014	0.986	0.000
T93 Sequelae of injuries of lower limb	0.014	0.986	0.000
S50-S59 Injuries to the elbow and forearm	0.014	0.986	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.014	0.986	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.014	0.986	0.000
M79.8 Other specified soft tissue disorders	0.014	0.986	0.000
S32 Fracture of lumbar spine and pelvis	0.014	0.986	0.000
T92 Sequelae of injuries of upper limb	0.014	0.986	0.000
# Top node	0.013	0.987	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.013	0.987	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.013	0.987	0.000
R07.3 Other chest pain	0.000	0.987	0.013
S72.10 Pertrochanteric fracture (closed)	0.013	0.987	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
T98 Sequelae of other and unspecified effects of external causes	0.013	0.987	0.000
T95 Sequelae of burns, corrosions and frostbite	0.013	0.987	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.013	0.987	0.000
T91 Sequelae of injuries of neck and trunk	0.013	0.987	0.000
T90 Sequelae of injuries of head	0.013	0.987	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.013	0.987	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.013	0.987	0.000
M70-M79 Other soft tissue disorders	0.013	0.987	0.000
S70.8 Other superficial injuries of hip and thigh	0.012	0.987	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.012	0.987	0.000
S70.1 Contusion of thigh	0.012	0.987	0.000
S70.0 Contusion of hip	0.012	0.987	0.000
T51.0 Ethanol	0.013	0.987	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.987	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.012	0.987	0.000
T43.6 Psychostimulants with abuse potential	0.012	0.987	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.987	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.012	0.987	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.012	0.987	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.987	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.012	0.987	0.000
C79 Secondary malignant neoplasm of other sites	0.013	0.987	0.000
T65 Toxic effect of other and unspecified substances	0.012	0.987	0.000
T63 Toxic effect of contact with venomous animals	0.012	0.987	0.000
T62 Toxic effect of other noxious substances eaten as food	0.012	0.987	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.012	0.987	0.000
T60 Toxic effect of pesticides	0.012	0.987	0.000
T59 Toxic effect of other gases, fumes and vapours	0.012	0.987	0.000
T57 Toxic effect of other inorganic substances	0.012	0.987	0.000
T56 Toxic effect of metals	0.012	0.987	0.000
T54 Toxic effect of corrosive substances	0.012	0.987	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.012	0.987	0.000
T52 Toxic effect of organic solvents	0.012	0.987	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.012	0.987	0.000
T58 Toxic effect of carbon monoxide	0.012	0.987	0.000
T55 Toxic effect of soaps and detergents	0.012	0.987	0.000
Chapter II Neoplasms	0.012	0.988	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.012	0.988	0.000
Chapter VI Diseases of the nervous system	0.012	0.988	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.012	0.988	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.012	0.988	0.000
S37 Injury of urinary and pelvic organs	0.012	0.988	0.000
S36 Injury of intra-abdominal organs	0.012	0.988	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.012	0.988	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.012	0.988	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.012	0.988	0.000
S31 Open wound of abdomen, lower back and pelvis	0.012	0.988	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.012	0.988	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.012	0.988	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
T42.4 Benzodiazepines	0.012	0.988	0.000
Chapter XX External causes of morbidity and mortality	0.012	0.988	0.000
S62 Fracture at wrist and hand level	0.012	0.988	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.012	0.988	0.000
S72.11 Pertrochanteric fracture (open)	0.012	0.988	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.012	0.988	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.012	0.988	0.000
T40.2 Other opioids	0.012	0.988	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.012	0.988	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.012	0.988	0.000
S00 Superficial injury of head	0.012	0.988	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.012	0.988	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.012	0.988	0.000
T39.4 Antirheumatics, not elsewhere classified	0.012	0.988	0.000
T39.2 Pyrazolone derivatives	0.012	0.988	0.000
T39.0 Salicylates	0.012	0.988	0.000
M80-M85 Disorders of bone density and structure	0.012	0.988	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.011	0.988	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.011	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.011	0.988	0.000
T42.3 Barbiturates	0.011	0.988	0.000
T42.2 Succinimides and oxazolidinediones	0.011	0.988	0.000
T42.1 Iminostilbenes	0.011	0.988	0.000
T42.0 Hydantoin derivatives	0.011	0.988	0.000
S29 Other and unspecified injuries of thorax	0.011	0.988	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.011	0.988	0.000
S27 Injury of other and unspecified intrathoracic organs	0.011	0.988	0.000
S26 Injury of heart	0.011	0.988	0.000
S25 Injury of blood vessels of thorax	0.011	0.988	0.000
S24 Injury of nerves and spinal cord at thorax level	0.011	0.988	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.011	0.988	0.000
S21 Open wound of thorax	0.011	0.988	0.000
S20 Superficial injury of thorax	0.011	0.988	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.011	0.988	0.000
S69 Other and unspecified injuries of wrist and hand	0.011	0.989	0.000
S67 Crushing injury of wrist and hand	0.011	0.989	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.011	0.989	0.000
S65 Injury of blood vessels at wrist and hand level	0.011	0.989	0.000
S64 Injury of nerves at wrist and hand level	0.011	0.989	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.011	0.989	0.000
S60 Superficial injury of wrist and hand	0.011	0.989	0.000
S68 Traumatic amputation of wrist and hand	0.011	0.989	0.000
S72.21 Subtrochanteric fracture (open)	0.011	0.989	0.000
S72.20 Subtrochanteric fracture (closed)	0.011	0.989	0.000
S72.31 Fracture of shaft of femur (open)	0.011	0.989	0.000
S72.30 Fracture of shaft of femur (closed)	0.011	0.989	0.000
S72.41 Fracture of lower end of femur (open)	0.011	0.989	0.000
S72.40 Fracture of lower end of femur (closed)	0.011	0.989	0.000
S72.71 Multiple fractures of femur (open)	0.011	0.989	0.000
S72.70 Multiple fractures of femur (closed)	0.011	0.989	0.000
S72.81 Fractures of other parts of femur (open)	0.011	0.989	0.000
S72.80 Fractures of other parts of femur (closed)	0.011	0.989	0.000
S72.91 Fracture of femur, part unspecified (open)	0.011	0.989	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.011	0.989	0.000
S80 Superficial injury of lower leg	0.011	0.989	0.000
G40-G47 Episodic and paroxysmal disorders	0.011	0.989	0.000
Chapter VIII Diseases of the ear and mastoid process	0.011	0.989	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.011	0.989	0.000
S71.7 Multiple open wounds of of hip and thigh	0.011	0.989	0.000
S71.1 Open wound of thigh	0.011	0.989	0.000
S71.0 Open wound of hip	0.011	0.989	0.000
S73.1 Sprain and strain of hip	0.011	0.989	0.000
S73.0 Dislocation of hip	0.011	0.989	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.011	0.989	0.000
S74.8 Injury of other nerves at hip and thigh level	0.011	0.989	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.011	0.989	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.011	0.989	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.011	0.989	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.011	0.989	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.011	0.989	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.011	0.989	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.011	0.989	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.011	0.989	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.011	0.989	0.000
S75.0 Injury of femoral artery	0.011	0.989	0.000
S76.1 Injury of quadriceps muscle and tendon	0.011	0.989	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.011	0.989	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.011	0.989	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.011	0.989	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.011	0.989	0.000
S76.0 Injury of muscle and tendon of hip	0.011	0.989	0.000
S77.2 Crushing injury of hip with thigh	0.011	0.989	0.000
S77.1 Crushing injury of thigh	0.011	0.989	0.000
S77.0 Crushing injury of hip	0.011	0.989	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.011	0.989	0.000
S78.1 Traumatic amputation at level between hip and knee	0.011	0.989	0.000
S78.0 Traumatic amputation at hip joint	0.011	0.989	0.000
S79.9 Unspecified injury of hip and thigh	0.011	0.989	0.000
S79.8 Other specified injuries of hip and thigh	0.011	0.989	0.000
S79.7 Multiple injuries of hip and thigh	0.011	0.989	0.000
T50.8 Diagnostic agents	0.011	0.989	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.4 Drugs affecting uric acid metabolism	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.011	0.989	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.011	0.989	0.000
T40.8 Lysergide [LSD]	0.011	0.989	0.000
T40.7 Cannabis (derivatives)	0.011	0.989	0.000
T40.6 Other and unspecified narcotics	0.011	0.989	0.000
T40.5 Cocaine	0.011	0.989	0.000
T40.4 Other synthetic narcotics	0.011	0.989	0.000
T40.3 Methadone	0.011	0.989	0.000
T40.1 Heroin	0.011	0.989	0.000
T40.0 Opium	0.011	0.989	0.000
S19 Other and unspecified injuries of neck	0.011	0.989	0.000
S17 Crushing injury of neck	0.011	0.989	0.000
S15 Injury of blood vessels at neck level	0.011	0.989	0.000
S14 Injury of nerves and spinal cord at neck level	0.011	0.989	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.011	0.989	0.000
S12 Fracture of neck	0.011	0.989	0.000
S11 Open wound of neck	0.011	0.989	0.000
S10 Superficial injury of neck	0.011	0.989	0.000
S18 Traumatic amputation at neck level	0.011	0.989	0.000
S16 Injury of muscle and tendon at neck level	0.011	0.989	0.000
S61 Open wound of wrist and hand	0.011	0.989	0.000
S99 Other and unspecified injuries of ankle and foot	0.011	0.989	0.000
S98 Traumatic amputation of ankle and foot	0.011	0.989	0.000
S97 Crushing injury of ankle and foot	0.011	0.989	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.011	0.989	0.000
S95 Injury of blood vessels at ankle and foot level	0.011	0.989	0.000
S94 Injury of nerves at ankle and foot level	0.011	0.989	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.011	0.989	0.000
S92 Fracture of foot, except ankle	0.011	0.989	0.000
S91 Open wound of ankle and foot	0.011	0.989	0.000
S90 Superficial injury of ankle and foot	0.011	0.989	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.011	0.989	0.000
T05 Traumatic amputations involving multiple body regions	0.011	0.989	0.000
T04 Crushing injuries involving multiple body regions	0.011	0.989	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.011	0.989	0.000
T02 Fractures involving multiple body regions	0.011	0.989	0.000
T01 Open wounds involving multiple body regions	0.011	0.989	0.000
T00 Superficial injuries involving multiple body regions	0.011	0.989	0.000
T07 Unspecified multiple injuries	0.011	0.989	0.000
T14 Injury of unspecified body region	0.011	0.989	0.000
T13 Other injuries of lower limb, level unspecified	0.011	0.989	0.000
T11 Other injuries of upper limb, level unspecified	0.011	0.989	0.000
T09 Other injuries of spine and trunk, level unspecified	0.011	0.989	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.011	0.989	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.011	0.989	0.000
T12 Fracture of lower limb, level unspecified	0.011	0.989	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.011	0.989	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.011	0.989	0.000
T10 Fracture of upper limb, level unspecified	0.011	0.989	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.011	0.989	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.011	0.989	0.000
T08 Fracture of spine, level unspecified	0.011	0.989	0.000
T19 Foreign body in genito-urinary tract	0.011	0.989	0.000
T18 Foreign body in alimentary tract	0.011	0.989	0.000
T17 Foreign body in respiratory tract	0.011	0.989	0.000
T15 Foreign body on external eye	0.011	0.989	0.000
T16 Foreign body in ear	0.011	0.989	0.000
T25 Burn and corrosion of ankle and foot	0.011	0.989	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.011	0.989	0.000
T23 Burn and corrosion of wrist and hand	0.011	0.989	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.011	0.989	0.000
T21 Burn and corrosion of trunk	0.011	0.989	0.000
T20 Burn and corrosion of head and neck	0.011	0.989	0.000
T28 Burn and corrosion of other internal organs	0.011	0.989	0.000
T27 Burn and corrosion of respiratory tract	0.011	0.989	0.000
T26 Burn and corrosion confined to eye and adnexa	0.011	0.989	0.000
T32 Corrosions classified according to extent of body surface involved	0.011	0.989	0.000
T31 Burns classified according to extent of body surface involved	0.011	0.989	0.000
T30 Burn and corrosion, body region unspecified	0.011	0.989	0.000
T29 Burns and corrosions of multiple body regions	0.011	0.989	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.011	0.989	0.000
T34 Frostbite with tissue necrosis	0.011	0.989	0.000
T33 Superficial frostbite	0.011	0.989	0.000
T78 Adverse effects, not elsewhere classified	0.011	0.989	0.000
T75 Effects of other external causes	0.011	0.989	0.000
T74 Maltreatment syndromes	0.011	0.989	0.000
T73 Effects of other deprivation	0.011	0.989	0.000
T70 Effects of air pressure and water pressure	0.011	0.989	0.000
T69 Other effects of reduced temperature	0.011	0.989	0.000
T67 Effects of heat and light	0.011	0.989	0.000
T71 Asphyxiation	0.011	0.989	0.000
T68 Hypothermia	0.011	0.989	0.000
T66 Unspecified effects of radiation	0.011	0.989	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.011	0.989	0.000
S32.5 Fracture of pubis	0.011	0.989	0.000
S32.4 Fracture of acetabulum	0.011	0.989	0.000
T92.1 Sequelae of fracture of arm	0.011	0.989	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.011	0.989	0.000
S48 Traumatic amputation of shoulder and upper arm	0.011	0.989	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.011	0.989	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.011	0.989	0.000
S44 Injury of nerves at shoulder and upper arm level	0.011	0.989	0.000
S41 Open wound of shoulder and upper arm	0.011	0.989	0.000
S40 Superficial injury of shoulder and upper arm	0.011	0.989	0.000
S47 Crushing injury of shoulder and upper arm	0.011	0.989	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.011	0.989	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.011	0.989	0.000
C15-C26 Malignant neoplasms of digestive organs	0.011	0.989	0.000
T93.2 Sequelae of other fractures of lower limb	0.011	0.989	0.000
S89 Other and unspecified injuries of lower leg	0.011	0.989	0.000
S88 Traumatic amputation of lower leg	0.011	0.989	0.000
S87 Crushing injury of lower leg	0.011	0.989	0.000
S86 Injury of muscle and tendon at lower leg level	0.011	0.989	0.000
S85 Injury of blood vessels at lower leg level	0.011	0.989	0.000
S84 Injury of nerves at lower leg level	0.011	0.989	0.000
S81 Open wound of lower leg	0.011	0.989	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.011	0.989	0.000
S42 Fracture of shoulder and upper arm	0.011	0.989	0.000
M50-M54 Other dorsopathies	0.011	0.989	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.011	0.989	0.000
S08 Traumatic amputation of part of head	0.011	0.989	0.000
S07 Crushing injury of head	0.011	0.989	0.000
S06 Intracranial injury	0.011	0.989	0.000
S05 Injury of eye and orbit	0.011	0.989	0.000
S04 Injury of cranial nerves	0.011	0.989	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.011	0.989	0.000
E10-E14 Diabetes mellitus	0.011	0.989	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.011	0.989	0.000
S02 Fracture of skull and facial bones	0.011	0.989	0.000
T51.9 Alcohol, unspecified	0.010	0.989	0.000
T51.8 Other alcohols	0.010	0.989	0.000
T51.3 Fusel oil	0.010	0.989	0.000
T51.2 2-Propanol	0.010	0.989	0.000
T51.1 Methanol	0.010	0.989	0.000
T36.9 Systemic antibiotic, unspecified	0.010	0.989	0.000
T36.8 Other systemic antibiotics	0.010	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.010	0.989	0.000
T36.6 Rifamycins	0.010	0.989	0.000
T36.5 Aminoglycosides	0.010	0.989	0.000
T36.4 Tetracyclines	0.010	0.989	0.000
T36.3 Macrolides	0.010	0.989	0.000
T36.2 Chloramphenicol group	0.010	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.010	0.989	0.000
T36.0 Penicillins	0.010	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.010	0.989	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.010	0.989	0.000
T37.5 Antiviral drugs	0.010	0.989	0.000
T37.4 Anthelminthics	0.010	0.989	0.000
T37.3 Other antiprotozoal drugs	0.010	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.010	0.989	0.000
T37.1 Antimycobacterial drugs	0.010	0.989	0.000
T37.0 Sulphonamides	0.010	0.989	0.000
T38.9 Other and unspecified hormone antagonists	0.010	0.989	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.010	0.989	0.000
T38.7 Androgens and anabolic congeners	0.010	0.989	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.010	0.989	0.000
T38.5 Other oestrogens and progestogens	0.010	0.989	0.000
T38.4 Oral contraceptives	0.010	0.989	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.010	0.989	0.000
T38.2 Antithyroid drugs	0.010	0.989	0.000
T38.1 Thyroid hormones and substitutes	0.010	0.989	0.000
T38.0 Glucocorticoids and synthetic analogues	0.010	0.989	0.000
T41.5 Therapeutic gases	0.010	0.989	0.000
T41.4 Anaesthetic, unspecified	0.010	0.989	0.000
T41.3 Local anaesthetics	0.010	0.989	0.000
T41.2 Other and unspecified general anaesthetics	0.010	0.989	0.000
T41.1 Intravenous anaesthetics	0.010	0.989	0.000
T41.0 Inhaled anaesthetics	0.010	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.010	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.989	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.989	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.010	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.989	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.010	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.010	0.989	0.000
T44.0 Anticholinesterase agents	0.010	0.989	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.010	0.989	0.000
T45.8 Other primarily systemic and haematological agents	0.010	0.989	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.010	0.989	0.000
T45.6 Fibrinolysis-affecting drugs	0.010	0.989	0.000
T45.5 Anticoagulants	0.010	0.989	0.000
T45.4 Iron and its compounds	0.010	0.989	0.000
T45.3 Enzymes, not elsewhere classified	0.010	0.989	0.000
T45.2 Vitamins, not elsewhere classified	0.010	0.989	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.010	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.010	0.989	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.010	0.989	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.010	0.989	0.000
T46.7 Peripheral vasodilators	0.010	0.989	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.010	0.989	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.989	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.989	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.010	0.989	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.010	0.989	0.000
T46.1 Calcium-channel blockers	0.010	0.989	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.010	0.989	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.010	0.989	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.010	0.989	0.000
T47.7 Emetics	0.010	0.989	0.000
T47.6 Antidiarrhoeal drugs	0.010	0.989	0.000
T47.5 Digestants	0.010	0.989	0.000
T47.4 Other laxatives	0.010	0.989	0.000
T47.3 Saline and osmotic laxatives	0.010	0.989	0.000
T47.2 Stimulant laxatives	0.010	0.989	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.010	0.989	0.000
T47.0 Histamine H(2)-receptor antagonists	0.010	0.989	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.010	0.989	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.010	0.989	0.000
T48.5 Anti-common-cold drugs	0.010	0.989	0.000
T48.4 Expectorants	0.010	0.989	0.000
T48.3 Antitussives	0.010	0.989	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.010	0.989	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.010	0.989	0.000
T48.0 Oxytocic drugs	0.010	0.989	0.000
T49.9 Topical agent, unspecified	0.010	0.989	0.000
T49.8 Other topical agents	0.010	0.989	0.000
T49.7 Dental drugs, topically applied	0.010	0.989	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.010	0.989	0.000
T49.5 Ophthalmological drugs and preparations	0.010	0.989	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.010	0.989	0.000
T49.3 Emollients, demulcents and protectants	0.010	0.989	0.000
T49.2 Local astringents and local detergents	0.010	0.989	0.000
T49.1 Antipruritics	0.010	0.989	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.010	0.989	0.000
M25 Other joint disorders, not elsewhere classified	0.011	0.989	0.000
M20-M25 Other joint disorders	0.011	0.989	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.010	0.989	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.010	0.989	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.010	0.989	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.010	0.989	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.010	0.989	0.000
T93.1 Sequelae of fracture of femur	0.010	0.989	0.000
T93.0 Sequelae of open wound of lower limb	0.010	0.989	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.010	0.989	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.010	0.989	0.000
S09 Other and unspecified injuries of head	0.010	0.989	0.000
S59 Other and unspecified injuries of forearm	0.010	0.989	0.000
S58 Traumatic amputation of forearm	0.010	0.989	0.000
S57 Crushing injury of forearm	0.010	0.989	0.000
S56 Injury of muscle and tendon at forearm level	0.010	0.989	0.000
S55 Injury of blood vessels at forearm level	0.010	0.989	0.000
S54 Injury of nerves at forearm level	0.010	0.989	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.010	0.989	0.000
S51 Open wound of forearm	0.010	0.989	0.000
S50 Superficial injury of forearm	0.010	0.989	0.000
T87 Complications peculiar to reattachment and amputation	0.010	0.990	0.000
T86 Failure and rejection of transplanted organs and tissues	0.010	0.990	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.010	0.990	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.010	0.990	0.000
H80-H83 Diseases of inner ear	0.010	0.990	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.010	0.990	0.000
M79.88 Other specified soft tissue disorders (Other)	0.010	0.990	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.010	0.990	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.010	0.990	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.010	0.990	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.010	0.990	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.010	0.990	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.010	0.990	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.010	0.990	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.010	0.990	0.000
S32.0 Fracture of lumbar vertebra	0.010	0.990	0.000
C79.2 Secondary malignant neoplasm of skin	0.010	0.990	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
M45-M49 Spondylopathies	0.010	0.990	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.010	0.990	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.010	0.990	0.000
S32.3 Fracture of ilium	0.010	0.990	0.000
S32.2 Fracture of coccyx	0.010	0.990	0.000
S32.1 Fracture of sacrum	0.010	0.990	0.000
M79.6 Pain in limb	0.010	0.990	0.000
E11 Non-insulin-dependent diabetes mellitus	0.010	0.990	0.000
M40-M43 Deforming dorsopathies	0.010	0.990	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.010	0.990	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.010	0.990	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.010	0.990	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.010	0.990	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.010	0.990	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.010	0.990	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.010	0.990	0.000
T92.0 Sequelae of open wound of upper limb	0.010	0.990	0.000
Chapter V Mental and behavioural disorders	0.010	0.990	0.000
M81 Osteoporosis without pathological fracture	0.010	0.990	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.010	0.990	0.000
V10-V19 Pedal cyclist injured in transport accident	0.010	0.990	0.000
S82 Fracture of lower leg, including ankle	0.010	0.990	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations