TreeWAS – Variant ID: rs527616

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27 Other disorders of adrenal gland	0.000	0.974	0.026
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.975	0.025
E27.9 Disorder of adrenal gland, unspecified	0.000	0.975	0.024
E27.1 Primary adrenocortical insufficiency	0.000	0.977	0.023
E29.1 Testicular hypofunction	0.000	0.979	0.021
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.979	0.021
E29 Testicular dysfunction	0.000	0.980	0.020
E20-E35 Disorders of other endocrine glands	0.000	0.980	0.020
E27.8 Other specified disorders of adrenal gland	0.000	0.980	0.020
E27.5 Adrenomedullary hyperfunction	0.000	0.981	0.019
E27.0 Other adrenocortical overactivity	0.000	0.981	0.019
E26 Hyperaldosteronism	0.000	0.982	0.018
E24 Cushing's syndrome	0.000	0.982	0.017
E34 Other endocrine disorders	0.000	0.983	0.017
E23 Hypofunction and other disorders of pituitary gland	0.000	0.984	0.016
E26.0 Primary hyperaldosteronism	0.000	0.984	0.016
E25 Adrenogenital disorders	0.000	0.984	0.016
E32 Diseases of thymus	0.000	0.985	0.015
E31 Polyglandular dysfunction	0.000	0.985	0.015
E27.2 Addisonian crisis	0.000	0.985	0.015
E24.2 Drug-induced Cushing's syndrome	0.000	0.985	0.015
E29.8 Other testicular dysfunction	0.000	0.985	0.015
E29.0 Testicular hyperfunction	0.000	0.985	0.015
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.985	0.015
E30 Disorders of puberty, not elsewhere classified	0.000	0.985	0.015
E23.7 Disorder of pituitary gland, unspecified	0.000	0.986	0.014
E24.8 Other Cushing's syndrome	0.000	0.986	0.014
E24.0 Pituitary-dependent Cushing's disease	0.000	0.986	0.014
E29.9 Testicular dysfunction, unspecified	0.000	0.986	0.014
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.014	0.986	0.000
E34.8 Other specified endocrine disorders	0.000	0.986	0.014
E34.0 Carcinoid syndrome	0.000	0.986	0.013
E26.8 Other hyperaldosteronism	0.000	0.987	0.013
E26.1 Secondary hyperaldosteronism	0.000	0.987	0.013
E26.9 Hyperaldosteronism, unspecified	0.000	0.987	0.013
E23.6 Other disorders of pituitary gland	0.000	0.987	0.013
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.987	0.013
E24.3 Ectopic ACTH syndrome	0.000	0.987	0.013
E24.1 Nelson's syndrome	0.000	0.987	0.013
E34.3 Short stature, not elsewhere classified	0.000	0.987	0.012
E34.5 Androgen resistance syndrome	0.000	0.988	0.012
E34.4 Constitutional tall stature	0.000	0.988	0.012
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.988	0.012
E34.1 Other hypersecretion of intestinal hormones	0.000	0.988	0.012
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.988	0.012
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.988	0.012
E23.1 Drug-induced hypopituitarism	0.000	0.988	0.012
E34.9 Endocrine disorder, unspecified	0.000	0.988	0.012
E23.2 Diabetes insipidus	0.000	0.988	0.012
E25.9 Adrenogenital disorder, unspecified	0.000	0.988	0.011
E25.8 Other adrenogenital disorders	0.000	0.988	0.011
E22 Hyperfunction of pituitary gland	0.000	0.989	0.011
R86.8 Other abnormal findings	0.000	0.989	0.011
E32.9 Disease of thymus, unspecified	0.000	0.989	0.011
E31.0 Autoimmune polyglandular failure	0.000	0.989	0.011
E32.8 Other diseases of thymus	0.000	0.989	0.011
E32.1 Abscess of thymus	0.000	0.989	0.011
E32.0 Persistent hyperplasia of thymus	0.000	0.989	0.011
E31.9 Polyglandular dysfunction, unspecified	0.000	0.989	0.011
E31.8 Other polyglandular dysfunction	0.000	0.989	0.011
E31.1 Polyglandular hyperfunction	0.000	0.989	0.011
E30.9 Disorder of puberty, unspecified	0.000	0.989	0.011
E30.8 Other disorders of puberty	0.000	0.989	0.011
E30.1 Precocious puberty	0.000	0.989	0.011
E30.0 Delayed puberty	0.000	0.989	0.011
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.989	0.011
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.989	0.011
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.989	0.011
E28 Ovarian dysfunction	0.000	0.989	0.011
M23.5 Chronic instability of knee	0.011	0.989	0.000
R86 Abnormal findings in specimens from male genital organs	0.000	0.989	0.011
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.010	0.990	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.990	0.010
R86.0 Abnormal level of enzymes	0.000	0.990	0.009
E23.0 Hypopituitarism	0.000	0.990	0.009
R86.9 Unspecified abnormal finding	0.000	0.990	0.009
E20 Hypoparathyroidism	0.000	0.990	0.009
Z49.1 Extracorporeal dialysis	0.000	0.991	0.009
E24.9 Cushing's syndrome, unspecified	0.000	0.991	0.009
E22.1 Hyperprolactinaemia	0.000	0.991	0.009
R86.6 Abnormal cytological findings	0.000	0.991	0.009
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.991	0.009
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.009	0.991	0.000
G83 Other paralytic syndromes	0.009	0.991	0.000
G80 Infantile cerebral palsy	0.009	0.991	0.000
E22.8 Other hyperfunction of pituitary gland	0.000	0.991	0.008
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.008	0.992	0.000
G80.9 Infantile cerebral palsy, unspecified	0.008	0.992	0.000
R86.5 Abnormal microbiological findings	0.000	0.992	0.008
Z49.2 Other dialysis	0.000	0.992	0.008
R86.7 Abnormal histological findings	0.000	0.992	0.008
E28.9 Ovarian dysfunction, unspecified	0.000	0.992	0.008
E28.8 Other ovarian dysfunction	0.000	0.992	0.008
E28.1 Androgen excess	0.000	0.992	0.008
E28.0 Oestrogen excess	0.000	0.992	0.008
E22.0 Acromegaly and pituitary gigantism	0.000	0.992	0.008
M23.57 Chronic instability of knee (Capsular ligament)	0.008	0.992	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.008	0.992	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.008	0.992	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.008	0.992	0.000
Z49 Care involving dialysis	0.000	0.992	0.008
R86.1 Abnormal level of hormones	0.000	0.992	0.008
M23.50 Chronic instability of knee (Multiple sites)	0.008	0.992	0.000
R86.4 Abnormal immunological findings	0.000	0.992	0.008
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.992	0.008
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.992	0.008
E21.4 Other specified disorders of parathyroid gland	0.000	0.992	0.008
G83.1 Monoplegia of lower limb	0.008	0.992	0.000
G83.9 Paralytic syndrome, unspecified	0.007	0.992	0.000
G83.2 Monoplegia of upper limb	0.007	0.993	0.000
E21.2 Other hyperparathyroidism	0.000	0.993	0.007
G80.2 Infantile hemiplegia	0.007	0.993	0.000
G83.3 Monoplegia, unspecified	0.007	0.993	0.000
G80.0 Spastic cerebral palsy	0.007	0.993	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.007	0.993	0.000
G80.1 Spastic diplegia	0.007	0.993	0.000
E20.0 Idiopathic hypoparathyroidism	0.000	0.993	0.007
S22.20 Fracture of sternum (closed)	0.000	0.993	0.007
G83.4 Cauda equina syndrome	0.007	0.993	0.000
F29 Unspecified nonorganic psychosis	0.000	0.993	0.007
E28.3 Primary ovarian failure	0.000	0.993	0.007
Z49.0 Preparatory care for dialysis	0.000	0.993	0.007
D12.0 Caecum	0.007	0.993	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.993	0.007
E20.1 Pseudohypoparathyroidism	0.000	0.994	0.006
G80.4 Ataxic cerebral palsy	0.006	0.994	0.000
G80.3 Dyskinetic cerebral palsy	0.006	0.994	0.000
G83.5 Locked-in syndrome	0.006	0.994	0.000
G83.0 Diplegia of upper limbs	0.006	0.994	0.000
G80.8 Other infantile cerebral palsy	0.006	0.994	0.000
G83.8 Other specified paralytic syndromes	0.006	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.994	0.006
G81 Hemiplegia	0.006	0.994	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.994	0.006
E20.8 Other hypoparathyroidism	0.001	0.994	0.005
E21.3 Hyperparathyroidism, unspecified	0.000	0.994	0.006
E20.9 Hypoparathyroidism, unspecified	0.001	0.995	0.005
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.995	0.005
G81.1 Spastic hemiplegia	0.005	0.995	0.000
G81.9 Hemiplegia, unspecified	0.005	0.995	0.000
M95.0 Acquired deformity of nose	0.005	0.995	0.000
L57.0 Actinic keratosis	0.000	0.995	0.005
E21.0 Primary hyperparathyroidism	0.000	0.995	0.005
G81.0 Flaccid hemiplegia	0.005	0.995	0.000
Y45.1 Salicylates	0.004	0.996	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.004	0.996	0.000
L71.9 Rosacea, unspecified	0.000	0.996	0.004
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.996	0.004
K85.1 Biliary acute pancreatitis	0.000	0.996	0.004
O36.5 Maternal care for poor foetal growth	0.004	0.996	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.004	0.996	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.996	0.004
N43.3 Hydrocele, unspecified	0.004	0.996	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.996	0.004
M43.02 Spondylolysis (Cervical region)	0.000	0.996	0.004
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
S80.0 Contusion of knee	0.004	0.996	0.000
D33.3 Cranial nerves	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.996	0.003
T92 Sequelae of injuries of upper limb	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.003	0.996	0.000
M43.0 Spondylolysis	0.000	0.997	0.003
H10.9 Conjunctivitis, unspecified	0.000	0.997	0.003
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.003
M23.8 Other internal derangements of knee	0.003	0.997	0.000
W07.0 Home	0.000	0.997	0.003
D04.5 Skin of trunk	0.000	0.997	0.003
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.997	0.003
S22.2 Fracture of sternum	0.000	0.997	0.003
D04 Carcinoma in situ of skin	0.000	0.997	0.003
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
T92.0 Sequelae of open wound of upper limb	0.003	0.997	0.000
G82 Paraplegia and tetraplegia	0.003	0.997	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.997	0.003
D04.9 Skin, unspecified	0.000	0.997	0.003
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.003	0.997	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.003	0.997	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.997	0.003
D06.9 Cervix, unspecified	0.000	0.997	0.003
E10.4 With neurological complications	0.003	0.997	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
M23.87 Other internal derangements of knee (Capsular ligament)	0.003	0.997	0.000
M43.09 Spondylolysis (Site unspecified)	0.000	0.997	0.003
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.997	0.003
D04.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.997	0.003
I71.0 Dissection of aorta [any part]	0.000	0.997	0.003
I71 Aortic aneurysm and dissection	0.000	0.997	0.003
D04.2 Skin of ear and external auricular canal	0.000	0.997	0.003
I46.0 Cardiac arrest with successful resuscitation	0.000	0.997	0.003
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.997	0.003
M43.04 Spondylolysis (Thoracic region)	0.000	0.997	0.003
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.997	0.003
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.997	0.003
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
C49.4 Connective and soft tissue of abdomen	0.000	0.997	0.003
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.003	0.997	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.997	0.003
Y45.4 Antirheumatics	0.003	0.997	0.000
K51.4 Pseudopolyposis of colon	0.003	0.997	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.000	0.997	0.003
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.003	0.997	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.997	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
S22.21 Fracture of sternum (open)	0.000	0.997	0.002
D04.8 Skin of other sites	0.000	0.997	0.002
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.997	0.003
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.997	0.002
G82.4 Spastic tetraplegia	0.002	0.997	0.000
G82.3 Flaccid tetraplegia	0.002	0.997	0.000
G82.0 Flaccid paraplegia	0.002	0.997	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.997	0.002
C49.5 Connective and soft tissue of pelvis	0.000	0.997	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.997	0.002
L05.9 Pilonidal cyst without abscess	0.000	0.997	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
D04.1 Skin of eyelid, including canthus	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
R44.1 Visual hallucinations	0.000	0.998	0.002
D04.4 Skin of scalp and neck	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.002	0.998	0.000
M23 Internal derangement of knee	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.000	0.998	0.002
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
L71.1 Rhinophyma	0.000	0.998	0.002
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
D04.0 Skin of lip	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
L57.5 Actinic granuloma	0.000	0.998	0.002
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.002	0.998	0.000
C10.9 Oropharynx, unspecified	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
S51.0 Open wound of elbow	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
L57.3 Poikiloderma of Civatte	0.000	0.998	0.002
L57.2 Cutis rhomboidalis nuchae	0.000	0.998	0.002
L57.1 Actinic reticuloid	0.000	0.998	0.002
M23.6 Other spontaneous disruption of ligament(s) of knee	0.002	0.998	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
J91 Pleural effusion in conditions classified elsewhere	0.002	0.998	0.000
E10.6 With other specified complications	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
M43.62 Torticollis-Cervical	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.998	0.002
J32.4 Chronic pansinusitis	0.000	0.998	0.002
N30.1 Interstitial cystitis (chronic)	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
J32 Chronic sinusitis	0.000	0.998	0.002
H10 Conjunctivitis	0.000	0.998	0.002
L71.8 Other rosacea	0.000	0.998	0.002
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
L71.0 Perioral dermatitis	0.000	0.998	0.002
O43.8 Other placental disorders	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.998	0.002
D06 Carcinoma in situ of cervix uteri	0.000	0.998	0.002
H49 Paralytic strabismus	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.002
R87.7 Abnormal histological findings	0.000	0.998	0.002
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.002	0.998	0.000
I45.9 Conduction disorder, unspecified	0.002	0.998	0.000
L56.4 Polymorphous light eruption	0.000	0.998	0.002
H10.3 Acute conjunctivitis, unspecified	0.000	0.998	0.002
M23.0 Cystic meniscus	0.002	0.998	0.000
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.000	0.998	0.002
M23.1 Discoid meniscus (congenital)	0.002	0.998	0.000
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
L56.3 Solar urticaria	0.000	0.998	0.002
L56.2 Photocontact dermatitis [berloque dermatitis]	0.000	0.998	0.002
L56.1 Drug photoallergic response	0.000	0.998	0.002
L56.0 Drug phototoxic response	0.000	0.998	0.002
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
F81.9 Developmental disorder of scholastic skills, unspecified	0.002	0.998	0.000
J98.8 Other specified respiratory disorders	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
M43.6 Torticollis	0.000	0.998	0.002
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.002	0.998	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.002	0.998	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.002	0.998	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.000	0.998	0.002
N43.2 Other hydrocele	0.002	0.998	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.998	0.002
C45 Mesothelioma	0.000	0.998	0.002
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
D06.1 Exocervix	0.000	0.998	0.002
E10.7 With multiple complications	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.000	0.998	0.002
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.002
M43 Other deforming dorsopathies	0.000	0.998	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.998	0.002
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
M23.4 Loose body in knee	0.002	0.998	0.000
N43.1 Infected hydrocele	0.002	0.998	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
H10.8 Other conjunctivitis	0.000	0.998	0.002
H10.2 Other acute conjunctivitis	0.000	0.998	0.002
J32.3 Chronic sphenoidal sinusitis	0.000	0.998	0.002
S51.7 Multiple open wounds of forearm	0.000	0.998	0.002
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.000	0.998	0.002
E10.0 With coma	0.002	0.998	0.000
H10.5 Blepharoconjunctivitis	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.998	0.002
H50 Other strabismus	0.000	0.998	0.002
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.998	0.002
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
S40 Superficial injury of shoulder and upper arm	0.000	0.998	0.002
D06.7 Other parts of cervix	0.000	0.998	0.002
H49.3 Total (external) ophthalmoplegia	0.000	0.998	0.002
J32.1 Chronic frontal sinusitis	0.000	0.998	0.002
O82.1 Delivery by emergency Caesarean section	0.000	0.998	0.002
S51 Open wound of forearm	0.000	0.998	0.002
H10.0 Mucopurulent conjunctivitis	0.000	0.998	0.001
H50.2 Vertical strabismus	0.000	0.998	0.002
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.998	0.002
S43.0 Dislocation of shoulder joint	0.000	0.998	0.002
D33.4 Spinal cord	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.000	0.998	0.001
W08.0 Home	0.002	0.998	0.000
L05 Pilonidal cyst	0.000	0.998	0.002
M23.07 Cystic meniscus-Capsular lig	0.001	0.998	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.00 Cystic meniscus (Multiple sites)	0.001	0.998	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.001	0.998	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.001	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.002	0.998	0.000
D06.0 Endocervix	0.000	0.998	0.001
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
N43.0 Encysted hydrocele	0.001	0.998	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.001	0.998	0.000
N30.3 Trigonitis	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
K37 Unspecified appendicitis	0.002	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
F25 Schizoaffective disorders	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
M43.68 Torticollis-Sacral/sacrococ	0.000	0.998	0.001
M43.67 Torticollis-Lumbosacral	0.000	0.998	0.001
M43.66 Torticollis-Lumbar	0.000	0.998	0.001
M43.65 Torticollis-Thoracolumbar	0.000	0.998	0.001
M43.64 Torticollis-Thoracic	0.000	0.998	0.001
M43.63 Torticollis-Cervicothoracic	0.000	0.998	0.001
M43.61 Torticollis-Occipit-atl-axl	0.000	0.998	0.001
M43.60 Torticollis-Mult site	0.000	0.998	0.001
M43.9 Deforming dorsopathy, unspecified	0.000	0.998	0.001
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.998	0.002
C45.2 Mesothelioma of pericardium	0.000	0.998	0.001
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.001
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.998	0.001
K83.2 Perforation of bile duct	0.001	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
M23.9 Internal derangement of knee, unspecified	0.001	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
F43.0 Acute stress reaction	0.000	0.998	0.002
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.001	0.998	0.000
F23 Acute and transient psychotic disorders	0.000	0.998	0.001
K83 Other diseases of biliary tract	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.001	0.998	0.000
M43.5 Other recurrent vertebral subluxation	0.000	0.998	0.001
M43.4 Other recurrent atlantoaxial subluxation	0.000	0.998	0.001
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.000	0.998	0.001
F28 Other nonorganic psychotic disorders	0.000	0.998	0.001
F24 Induced delusional disorder	0.000	0.998	0.001
M23.47 Loose body in knee-Capsular lig	0.001	0.998	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.001	0.998	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.998	0.001
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.998	0.000
D33.9 Central nervous system, unspecified	0.001	0.998	0.000
D33.7 Other specified parts of central nervous system	0.001	0.998	0.000
D33.1 Brain, infratentorial	0.001	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.000	0.998	0.001
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.001	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.001
H50.3 Intermittent heterotropia	0.000	0.998	0.001
B80 Enterobiasis	0.001	0.998	0.000
L55 Sunburn	0.000	0.998	0.001
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.999	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.999	0.001
L58 Radiodermatitis	0.000	0.999	0.001
D33.0 Brain, supratentorial	0.001	0.999	0.000
K83.3 Fistula of bile duct	0.001	0.999	0.000
M43.8 Other specified deforming dorsopathies	0.000	0.999	0.001
S71.1 Open wound of thigh	0.001	0.999	0.000
Z58.1 Exposure to air pollution	0.000	0.999	0.001
B07 Viral warts	0.000	0.999	0.001
T95 Sequelae of burns, corrosions and frostbite	0.001	0.999	0.000
K50.0 Crohn's disease of small intestine	0.001	0.999	0.000
K83.5 Biliary cyst	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
M43.69 Torticollis-Site unspe	0.000	0.999	0.001
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
D69.5 Secondary thrombocytopenia	0.001	0.999	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.999	0.000
R44.2 Other hallucinations	0.000	0.999	0.001
F22 Persistent delusional disorders	0.000	0.999	0.001
M23.46 Loose body in knee-O/unsp lat men	0.001	0.999	0.000
M23.43 Loose body in knee-Med lig/oth men	0.001	0.999	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.999	0.001
F25.8 Other schizoaffective disorders	0.000	0.999	0.001
O82.9 Delivery by Caesarean section, unspecified	0.000	0.999	0.001
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.001	0.999	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.001	0.999	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.001	0.999	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.001	0.999	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.999	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.001	0.999	0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.000	0.999	0.001
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
D33.2 Brain, unspecified	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.999	0.001
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
C46 Kaposi's sarcoma	0.000	0.999	0.001
G99 Other disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
M23.40 Loose body in knee-Mult sites	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations