TreeWAS – Variant ID: rs555007

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
M20 Acquired deformities of fingers and toes	0.956	0.044	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.948	0.052	0.000
M20-M25 Other joint disorders	0.946	0.054	0.000
M20.1 Hallux valgus (acquired)	0.940	0.060	0.000
M20.5 Other deformities of toe(s) (acquired)	0.938	0.062	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.912	0.088	0.000
M20.2 Hallux rigidus	0.895	0.105	0.000
M05-M14 Inflammatory polyarthropathies	0.890	0.110	0.000
M06 Other rheumatoid arthritis	0.868	0.132	0.000
M65-M68 Disorders of synovium and tendon	0.867	0.133	0.000
M80-M85 Disorders of bone density and structure	0.858	0.142	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.850	0.150	0.000
M31 Other necrotising vasculopathies	0.845	0.155	0.000
M15-M19 Arthrosis	0.835	0.165	0.000
M65 Synovitis and tenosynovitis	0.807	0.193	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.805	0.195	0.000
M95.0 Acquired deformity of nose	0.795	0.204	0.000
M16 Coxarthrosis [arthrosis of hip]	0.790	0.210	0.000
M45-M49 Spondylopathies	0.786	0.214	0.000
M06.9 Rheumatoid arthritis, unspecified	0.784	0.216	0.000
M40-M43 Deforming dorsopathies	0.771	0.229	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.770	0.230	0.000
M31.6 Other giant cell arteritis	0.763	0.237	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.760	0.240	0.000
M20.3 Other deformity of hallux (acquired)	0.759	0.241	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.755	0.245	0.000
K57 Diverticular disease of intestine	0.753	0.247	0.000
M60-M63 Disorders of muscles	0.753	0.247	0.000
M16.1 Other primary coxarthrosis	0.750	0.250	0.000
M91-M94 Chondropathies	0.747	0.253	0.000
M06.0 Seronegative rheumatoid arthritis	0.746	0.254	0.000
M86-M90 Other osteopathies	0.742	0.257	0.000
M85 Other disorders of bone density and structure	0.736	0.264	0.000
M20.4 Other hammer toe(s) (acquired)	0.731	0.269	0.000
M80 Osteoporosis with pathological fracture	0.725	0.275	0.000
M33 Dermatopolymyositis	0.723	0.277	0.000
M05 Seropositive rheumatoid arthritis	0.722	0.278	0.000
M20.0 Deformity of finger(s)	0.722	0.278	0.000
M06.3 Rheumatoid nodule	0.718	0.282	0.000
M06.4 Inflammatory polyarthropathy	0.715	0.285	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.708	0.292	0.000
M18 Arthrosis of first carpometacarpal joint	0.697	0.303	0.000
M82 Osteoporosis in diseases classified elsewhere	0.694	0.305	0.000
M65.1 Other infective (teno)synovitis	0.694	0.306	0.000
M30 Polyarteritis nodosa and related conditions	0.690	0.310	0.000
M48 Other spondylopathies	0.690	0.310	0.000
M00-M03 Infectious arthropathies	0.688	0.312	0.000
M35 Other systemic involvement of connective tissue	0.685	0.315	0.000
M31.9 Necrotising vasculopathy, unspecified	0.685	0.315	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.678	0.321	0.000
M32 Systemic lupus erythematosus	0.678	0.321	0.000
M16.5 Other posttraumatic coxarthrosis	0.677	0.323	0.000
M65.3 Trigger finger	0.674	0.326	0.000
M67 Other disorders of synovium and tendon	0.664	0.336	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.664	0.336	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.662	0.338	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.661	0.339	0.000
M95.2 Other acquired deformity of head	0.655	0.345	0.000
M99 Biomechanical lesions, not elsewhere classified	0.654	0.346	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.647	0.353	0.000
M84 Disorders of continuity of bone	0.645	0.355	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.640	0.360	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.639	0.361	0.000
M12 Other specific arthropathies	0.638	0.362	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.638	0.362	0.000
M08 Juvenile arthritis	0.638	0.362	0.000
M11 Other crystal arthropathies	0.638	0.362	0.000
M70-M79 Other soft tissue disorders	0.636	0.364	0.000
M24 Other specific joint derangements	0.634	0.366	0.000
M46 Other inflammatory spondylopathies	0.633	0.367	0.000
M48.0 Spinal stenosis	0.633	0.367	0.000
M85.8 Other specified disorders of bone density and structure	0.631	0.368	0.000
M41 Scoliosis	0.626	0.374	0.000
M14 Arthropathies in other diseases classified elsewhere	0.625	0.375	0.000
M06.8 Other specified rheumatoid arthritis	0.622	0.378	0.000
M06.2 Rheumatoid bursitis	0.622	0.378	0.000
M06.1 Adult-onset Still's disease	0.622	0.378	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.621	0.379	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.620	0.380	0.000
M90 Osteopathies in diseases classified elsewhere	0.619	0.381	0.000
M83 Adult osteomalacia	0.615	0.385	0.000
M65.8 Other synovitis and tenosynovitis	0.615	0.385	0.000
M48.02 Spinal stenosis (Cervical region)	0.615	0.385	0.000
M40 Kyphosis and lordosis	0.614	0.386	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.614	0.386	0.000
M16.7 Other secondary coxarthrosis	0.613	0.387	0.000
M62 Other disorders of muscle	0.612	0.388	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.610	0.390	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.610	0.390	0.000
M95.5 Acquired deformity of pelvis	0.610	0.390	0.000
M95.4 Acquired deformity of chest and rib	0.610	0.390	0.000
M95.3 Acquired deformity of neck	0.610	0.390	0.000
M95.1 Cauliflower ear	0.610	0.390	0.000
M21 Other acquired deformities of limbs	0.609	0.391	0.000
M34 Systemic sclerosis	0.608	0.392	0.000
M31.8 Other specified necrotising vasculopathies	0.606	0.394	0.000
M31.7 Microscopic polyangiitis	0.606	0.394	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.606	0.394	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.606	0.394	0.000
M31.2 Lethal midline granuloma	0.606	0.394	0.000
M31.1 Thrombotic microangiopathy	0.606	0.394	0.000
M31.0 Hypersensitivity angiitis	0.606	0.394	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.602	0.398	0.000
M15 Polyarthrosis	0.599	0.401	0.000
M07 Psoriatic and enteropathic arthropathies	0.596	0.404	0.000
M10 Gout	0.595	0.405	0.000
M92 Other juvenile osteochondrosis	0.594	0.406	0.000
M94 Other disorders of cartilage	0.592	0.408	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.585	0.415	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.581	0.419	0.000
M65.34 Trigger finger-Hand	0.580	0.420	0.000
M06.34 Rheumatoid nodule (Hand)	0.579	0.421	0.000
M49 Spondylopathies in diseases classified elsewhere	0.578	0.421	0.000
M65.2 Calcific tendinitis	0.578	0.422	0.000
M65.0 Abscess of tendon sheath	0.578	0.422	0.000
M82.1 Osteoporosis in endocrine disorders	0.577	0.423	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.577	0.423	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.577	0.423	0.000
M96.5 Postradiation scoliosis	0.577	0.423	0.000
M96.4 Postsurgical lordosis	0.577	0.423	0.000
M96.3 Postlaminectomy kyphosis	0.577	0.423	0.000
M96.2 Postradiation kyphosis	0.577	0.423	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.577	0.423	0.000
M66 Spontaneous rupture of synovium and tendon	0.577	0.423	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.575	0.425	0.000
M35.0 Sicca syndrome [Sjogren]	0.574	0.426	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.573	0.427	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.567	0.433	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.567	0.433	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.567	0.433	0.000
M33.2 Polymyositis	0.564	0.436	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.563	0.437	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.562	0.438	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.562	0.438	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.562	0.438	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.561	0.439	0.000
M24.2 Disorder of ligament	0.555	0.444	0.000
M42 Spinal osteochondrosis	0.553	0.447	0.000
M16.9 Coxarthrosis, unspecified	0.552	0.448	0.000
M85.6 Other cyst of bone	0.550	0.450	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.548	0.452	0.000
M87 Osteonecrosis	0.547	0.453	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.545	0.455	0.000
M85.0 Fibrous dysplasia (monostotic)	0.542	0.458	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.540	0.460	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.540	0.460	0.000
M61 Calcification and ossification of muscle	0.540	0.460	0.000
M60 Myositis	0.540	0.460	0.000
M88 Paget's disease of bone [osteitis deformans]	0.539	0.460	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.537	0.463	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.536	0.464	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.535	0.465	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.535	0.465	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.535	0.465	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.535	0.465	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.535	0.465	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.535	0.465	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.535	0.465	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.535	0.465	0.000
M86 Osteomyelitis	0.534	0.466	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.532	0.468	0.000
M90.7 Fracture of bone in neoplastic disease	0.531	0.469	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.529	0.471	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.529	0.471	0.000
M85.9 Disorder of bone density and structure, unspecified	0.528	0.472	0.000
M85.5 Aneurysmal bone cyst	0.528	0.472	0.000
M85.4 Solitary bone cyst	0.528	0.472	0.000
M85.3 Osteitis condensans	0.528	0.472	0.000
M85.2 Hyperostosis of skull	0.528	0.472	0.000
M85.1 Skeletal fluorosis	0.528	0.472	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.527	0.472	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.527	0.473	0.000
M31.3 Wegener's granulomatosis	0.526	0.474	0.000
M41.9 Scoliosis, unspecified	0.522	0.478	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.522	0.478	0.000
M80.8 Other osteoporosis with pathological fracture	0.520	0.480	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.520	0.480	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.520	0.480	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.520	0.480	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.520	0.480	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.519	0.481	0.000
M33.9 Dermatopolymyositis, unspecified	0.519	0.481	0.000
M33.1 Other dermatomyositis	0.519	0.481	0.000
M33.0 Juvenile dermatomyositis	0.519	0.481	0.000
M05.8 Other seropositive rheumatoid arthritis	0.518	0.482	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.518	0.482	0.000
M05.2 Rheumatoid vasculitis	0.518	0.482	0.000
M05.1 Rheumatoid lung disease	0.518	0.482	0.000
M05.0 Felty's syndrome	0.518	0.482	0.000
M47 Spondylosis	0.516	0.484	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.515	0.485	0.000
M06.38 Rheumatoid nodule (Other)	0.515	0.485	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.515	0.485	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.515	0.485	0.000
M06.33 Rheumatoid nodule (Forearm)	0.515	0.485	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.515	0.485	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.515	0.485	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.515	0.485	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.514	0.486	0.000
M67.1 Other contracture of tendon (sheath)	0.514	0.486	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.514	0.486	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.513	0.487	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.513	0.487	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.513	0.487	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.513	0.487	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.513	0.487	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.513	0.487	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.513	0.487	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.513	0.487	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.512	0.488	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.512	0.488	0.000
M62.8 Other specified disorders of muscle	0.512	0.488	0.000
M16.0 Primary coxarthrosis, bilateral	0.511	0.489	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.509	0.491	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.509	0.491	0.000
M17 Gonarthrosis [arthrosis of knee]	0.508	0.492	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.507	0.493	0.000
M43 Other deforming dorsopathies	0.506	0.494	0.000
M76 Enthesopathies of lower limb, excluding foot	0.504	0.496	0.000
M77 Other enthesopathies	0.503	0.497	0.000
M35.7 Hypermobility syndrome	0.502	0.498	0.000
M40.2 Other and unspecified kyphosis	0.501	0.498	0.000
M00 Pyogenic arthritis	0.501	0.499	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.500	0.500	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.500	0.500	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.500	0.500	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.500	0.500	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.498	0.502	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.498	0.502	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.498	0.502	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.498	0.502	0.000
M65.18 Other infective (teno)synovitis (Other)	0.498	0.502	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.498	0.502	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.498	0.502	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.498	0.502	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.498	0.502	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.498	0.502	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.498	0.502	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.498	0.502	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.498	0.502	0.000
M79.2 Neuralgia and neuritis, unspecified	0.497	0.503	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.495	0.505	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.495	0.505	0.000
M30.2 Juvenile polyarteritis	0.495	0.505	0.000
M30.0 Polyarteritis nodosa	0.495	0.505	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.495	0.505	0.000
M48.9 Spondylopathy, unspecified	0.495	0.505	0.000
M48.8 Other specified spondylopathies	0.495	0.505	0.000
M48.4 Fatigue fracture of vertebra	0.495	0.505	0.000
M48.3 Traumatic spondylopathy	0.495	0.505	0.000
M48.2 Kissing spine	0.495	0.505	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.495	0.505	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.493	0.507	0.000
M02 Reactive arthropathies	0.493	0.507	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.493	0.507	0.000
M84.4 Pathological fracture, not elsewhere classified	0.492	0.508	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.491	0.508	0.000
M35.8 Other specified systemic involvement of connective tissue	0.491	0.508	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.491	0.508	0.000
M35.5 Multifocal fibrosclerosis	0.491	0.508	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.491	0.508	0.000
M35.2 Behcet's disease	0.491	0.508	0.000
M35.1 Other overlap syndromes	0.491	0.508	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.491	0.509	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.490	0.510	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.486	0.513	0.000
M32.8 Other forms of systemic lupus erythematosus	0.486	0.513	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.486	0.513	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.486	0.513	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.486	0.513	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.486	0.513	0.000
M36.3 Arthropathy in other blood disorders	0.486	0.513	0.000
M36.2 Haemophilic arthropathy	0.486	0.513	0.000
M36.1 Arthropathy in neoplastic disease	0.486	0.513	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.486	0.513	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.485	0.515	0.000
M24.5 Contracture of joint	0.485	0.515	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.484	0.516	0.000
M65.39 Trigger finger-Site unspec	0.484	0.516	0.000
M65.38 Trigger finger-Other	0.484	0.516	0.000
M65.37 Trigger finger-Ankle/foot	0.484	0.516	0.000
M65.36 Trigger finger-Lower leg	0.484	0.516	0.000
M65.35 Trigger finger-Pelvic/thigh	0.484	0.516	0.000
M65.33 Trigger finger-Forearm	0.484	0.516	0.000
M65.32 Trigger finger-Upper arm	0.484	0.516	0.000
M65.31 Trigger finger-Shldr region	0.484	0.516	0.000
M65.30 Trigger finger-Mult sites	0.484	0.516	0.000
M71 Other bursopathies	0.481	0.519	0.000
M21.4 Flat foot [pes planus] (acquired)	0.479	0.520	0.000
M24.24 Disorder of ligament (Hand)	0.479	0.521	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.479	0.521	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.479	0.521	0.000
M93 Other osteochondropathies	0.477	0.523	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.476	0.523	0.000
M67.4 Ganglion	0.476	0.523	0.000
M67.3 Transient synovitis	0.476	0.523	0.000
M67.0 Short Achilles tendon (acquired)	0.476	0.523	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.476	0.524	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.476	0.524	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.476	0.524	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.476	0.524	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.476	0.524	0.000
M17.0 Primary gonarthrosis, bilateral	0.475	0.525	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.473	0.526	0.000
M79.1 Myalgia	0.472	0.528	0.000
M46.4 Discitis, unspecified	0.471	0.529	0.000
M99.9 Biomechanical lesion, unspecified	0.469	0.531	0.000
M99.8 Other biomechanical lesions	0.469	0.531	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.469	0.531	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.469	0.531	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.469	0.531	0.000
M99.4 Connective tissue stenosis of neural canal	0.469	0.531	0.000
M99.3 Osseous stenosis of neural canal	0.469	0.531	0.000
M99.2 Subluxation stenosis of neural canal	0.469	0.531	0.000
M99.1 Subluxation complex (vertebral)	0.469	0.531	0.000
M99.0 Segmental and somatic dysfunction	0.469	0.531	0.000
M94.8 Other specified disorders of cartilage	0.468	0.531	0.000
M67.8 Other specified disorders of synovium and tendon	0.468	0.532	0.000
M47.8 Other spondylosis	0.467	0.533	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.466	0.534	0.000
M24.0 Loose body in joint	0.464	0.536	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.464	0.536	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.464	0.536	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.464	0.536	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.464	0.536	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.464	0.536	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.464	0.536	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.464	0.536	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.464	0.536	0.000
M81 Osteoporosis without pathological fracture	0.463	0.537	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.463	0.537	0.000
M47.82 Other spondylosis (Cervical region)	0.463	0.537	0.000
M84.9 Disorder of continuity of bone, unspecified	0.462	0.538	0.000
M84.8 Other disorders of continuity of bone	0.462	0.538	0.000
M84.3 Stress fracture, not elsewhere classified	0.462	0.538	0.000
M84.2 Delayed union of fracture	0.462	0.538	0.000
M89 Other disorders of bone	0.462	0.538	0.000
M16.3 Other dysplastic coxarthrosis	0.459	0.540	0.000
M84.0 Malunion of fracture	0.458	0.542	0.000
M08.9 Juvenile arthritis, unspecified	0.457	0.542	0.000
M08.8 Other juvenile arthritis	0.457	0.542	0.000
M08.4 Pauciarticular juvenile arthritis	0.457	0.542	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.457	0.542	0.000
M08.2 Juvenile arthritis with systemic onset	0.457	0.542	0.000
M08.1 Juvenile ankylosing spondylitis	0.457	0.542	0.000
M08.0 Juvenile rheumatoid arthritis	0.457	0.542	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.457	0.542	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.457	0.542	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.457	0.542	0.000
M09.0 Juvenile arthritis in psoriasis	0.457	0.542	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.457	0.542	0.000
M12.5 Traumatic arthropathy	0.457	0.542	0.000
M12.4 Intermittent hydrarthrosis	0.457	0.542	0.000
M12.3 Palindromic rheumatism	0.457	0.542	0.000
M12.2 Villonodular synovitis (pigmented)	0.457	0.542	0.000
M12.1 Kaschin-Beck disease	0.457	0.542	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.457	0.542	0.000
M11.9 Crystal arthropathy, unspecified	0.457	0.542	0.000
M11.8 Other specified crystal arthropathies	0.457	0.542	0.000
M11.1 Familial chondrocalcinosis	0.457	0.542	0.000
M11.0 Hydroxyapatite deposition disease	0.457	0.542	0.000
M11.2 Other chondrocalcinosis	0.457	0.543	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.456	0.544	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.456	0.544	0.000
M24.9 Joint derangement, unspecified	0.455	0.545	0.000
M24.7 Protrusio acetabuli	0.455	0.545	0.000
M24.6 Ankylosis of joint	0.455	0.545	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.455	0.545	0.000
M46.8 Other specified inflammatory spondylopathies	0.454	0.546	0.000
M46.5 Other infective spondylopathies	0.454	0.546	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.454	0.546	0.000
M46.2 Osteomyelitis of vertebra	0.454	0.546	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.454	0.546	0.000
M46.0 Spinal enthesopathy	0.454	0.546	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.454	0.546	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.454	0.546	0.000
M48.04 Spinal stenosis (Thoracic region)	0.454	0.546	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.454	0.546	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.454	0.546	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.453	0.547	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.453	0.547	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.453	0.547	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.453	0.547	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.453	0.547	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.453	0.547	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.453	0.547	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.453	0.547	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.451	0.548	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.449	0.550	0.000
M41.8 Other forms of scoliosis	0.449	0.551	0.000
M41.5 Other secondary scoliosis	0.449	0.551	0.000
M41.4 Neuromuscular scoliosis	0.449	0.551	0.000
M41.3 Thoracogenic scoliosis	0.449	0.551	0.000
M41.2 Other idiopathic scoliosis	0.449	0.551	0.000
M41.1 Juvenile idiopathic scoliosis	0.449	0.551	0.000
M41.0 Infantile idiopathic scoliosis	0.449	0.551	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.448	0.551	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.448	0.551	0.000
M14.4 Arthropathy in amyloidosis	0.448	0.551	0.000
M14.3 Lipoid dermatoarthritis	0.448	0.551	0.000
M14.2 Diabetic arthropathy	0.448	0.551	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.448	0.551	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.448	0.551	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.447	0.553	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.446	0.554	0.000
M06.18 Adult-onset Still's disease (Other)	0.446	0.554	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.446	0.554	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.446	0.554	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.446	0.554	0.000
M06.14 Adult-onset Still's disease (Hand)	0.446	0.554	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.446	0.554	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.446	0.554	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.446	0.554	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.446	0.554	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.446	0.554	0.000
M06.28 Rheumatoid bursitis (Other)	0.446	0.554	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.446	0.554	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.446	0.554	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.446	0.554	0.000
M06.24 Rheumatoid bursitis (Hand)	0.446	0.554	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.446	0.554	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.446	0.554	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.446	0.554	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.446	0.554	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.446	0.554	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.446	0.554	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.446	0.554	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.446	0.554	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.446	0.554	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.446	0.554	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.446	0.554	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.446	0.554	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.446	0.554	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.446	0.554	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.446	0.554	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.446	0.554	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.444	0.556	0.000
M90.6 Osteitis deformans in neoplastic disease	0.444	0.556	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.444	0.556	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.444	0.556	0.000
M90.3 Osteonecrosis in caisson disease	0.444	0.556	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.444	0.556	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.444	0.556	0.000
M90.0 Tuberculosis of bone	0.444	0.556	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.444	0.556	0.000
M34.8 Other forms of systemic sclerosis	0.443	0.557	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.442	0.558	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.442	0.558	0.000
M83.9 Adult osteomalacia, unspecified	0.441	0.559	0.000
M83.8 Other adult osteomalacia	0.441	0.559	0.000
M83.5 Other drug-induced osteomalacia in adults	0.441	0.559	0.000
M83.4 Aluminum bone disease	0.441	0.559	0.000
M83.3 Adult osteomalacia due to malnutrition	0.441	0.559	0.000
M83.2 Adult osteomalacia due to malabsorption	0.441	0.559	0.000
M83.1 Senile osteomalacia	0.441	0.559	0.000
M83.0 Puerperal osteomalacia	0.441	0.559	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.441	0.559	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.441	0.559	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.441	0.559	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.441	0.559	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.441	0.559	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.441	0.559	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.441	0.559	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.441	0.559	0.000
M40.5 Lordosis, unspecified	0.440	0.560	0.000
M40.4 Other lordosis	0.440	0.560	0.000
M40.3 Flatback syndrome	0.440	0.560	0.000
M40.1 Other secondary kyphosis	0.440	0.560	0.000
M40.0 Postural kyphosis	0.440	0.560	0.000
M62.9 Disorder of muscle, unspecified	0.439	0.561	0.000
M62.6 Muscle strain	0.439	0.561	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.439	0.561	0.000
M62.4 Contracture of muscle	0.439	0.561	0.000
M62.3 Immobility syndrome (paraplegic)	0.439	0.561	0.000
M62.2 Ischaemic infarction of muscle	0.439	0.561	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.439	0.561	0.000
M62.0 Diastasis of muscle	0.439	0.561	0.000
M45 Ankylosing spondylitis	0.438	0.562	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.437	0.563	0.000
M21.9 Acquired deformity of limb, unspecified	0.437	0.563	0.000
M21.8 Other specified acquired deformities of limbs	0.437	0.563	0.000
M21.7 Unequal limb length (acquired)	0.437	0.563	0.000
M94.9 Disorder of cartilage, unspecified	0.436	0.563	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.436	0.564	0.000
M34.0 Progressive systemic sclerosis	0.436	0.564	0.000
M14.6 Neuropathic arthropathy	0.435	0.564	0.000
K90 Intestinal malabsorption	0.001	0.564	0.435
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.435	0.565	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.433	0.567	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.432	0.568	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.432	0.568	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.432	0.568	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.432	0.568	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.432	0.568	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.432	0.568	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.432	0.568	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.432	0.568	0.000
M21.1 Varus deformity, not elsewhere classified	0.432	0.568	0.000
M21.3 Wrist or foot drop (acquired)	0.431	0.569	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations