TreeWAS – Variant ID: rs55705316

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.9 Crohn's disease, unspecified	0.778	0.222	0.000
K50 Crohn's disease [regional enteritis]	0.757	0.243	0.000
K50.0 Crohn's disease of small intestine	0.697	0.303	0.000
K50.8 Other Crohn's disease	0.684	0.316	0.000
K50.1 Crohn's disease of large intestine	0.677	0.323	0.000
J33.9 Nasal polyp, unspecified	0.000	0.423	0.577
J33.0 Polyp of nasal cavity	0.000	0.438	0.562
J33 Nasal polyp	0.000	0.440	0.560
J33.1 Polypoid sinus degeneration	0.000	0.598	0.401
K50-K52 Noninfective enteritis and colitis	0.351	0.649	0.000
J33.8 Other polyp of sinus	0.000	0.678	0.322
K51 Ulcerative colitis	0.304	0.696	0.000
K51.9 Ulcerative colitis, unspecified	0.282	0.718	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.253	0.747	0.000
K51.5 Mucosal proctocolitis	0.236	0.764	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.219	0.781	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.212	0.788	0.000
K51.2 Ulcerative (chronic) proctitis	0.192	0.808	0.000
K51.8 Other ulcerative colitis	0.182	0.818	0.000
K52 Other non-infective gastro-enteritis and colitis	0.178	0.822	0.000
K51.4 Pseudopolyposis of colon	0.170	0.830	0.000
K52.3 Indeterminate colitis	0.151	0.849	0.000
K52.1 Toxic gastro-enteritis and colitis	0.141	0.859	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.128	0.872	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.112	0.888	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.100	0.900	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.903	0.097
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.904	0.096
J34 Other disorders of nose and nasal sinuses	0.000	0.906	0.094
J39 Other diseases of upper respiratory tract	0.000	0.915	0.085
J39.8 Other specified diseases of upper respiratory tract	0.000	0.919	0.081
J34.2 Deviated nasal septum	0.000	0.920	0.080
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.926	0.074
J37 Chronic laryngitis and laryngotracheitis	0.000	0.931	0.069
G55.2 Nerve root and plexus compressions in spondylosis	0.068	0.932	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.934	0.065
J32 Chronic sinusitis	0.000	0.938	0.062
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.938	0.061
J39.1 Other abscess of pharynx	0.000	0.938	0.061
J39.2 Other diseases of pharynx	0.000	0.940	0.060
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.940	0.060
J31.2 Chronic pharyngitis	0.000	0.943	0.057
J35 Chronic diseases of tonsils and adenoids	0.000	0.946	0.054
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.948	0.051
J32.1 Chronic frontal sinusitis	0.000	0.949	0.051
J32.0 Chronic maxillary sinusitis	0.000	0.949	0.051
J37.1 Chronic laryngotracheitis	0.000	0.950	0.049
J37.0 Chronic laryngitis	0.000	0.952	0.048
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.952	0.048
J31.1 Chronic nasopharyngitis	0.000	0.953	0.047
J32.4 Chronic pansinusitis	0.000	0.954	0.046
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.954	0.046
J32.3 Chronic sphenoidal sinusitis	0.000	0.955	0.045
J35.1 Hypertrophy of tonsils	0.000	0.958	0.042
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.961	0.039
J35.2 Hypertrophy of adenoids	0.000	0.961	0.039
J32.2 Chronic ethmoidal sinusitis	0.000	0.962	0.038
J32.8 Other chronic sinusitis	0.000	0.963	0.037
G30.9 Alzheimer's disease, unspecified	0.034	0.966	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.970	0.030
J30 Vasomotor and allergic rhinitis	0.000	0.971	0.029
J32.9 Chronic sinusitis, unspecified	0.000	0.972	0.028
J36 Peritonsillar abscess	0.000	0.973	0.027
D25.1 Intramural leiomyoma of uterus	0.000	0.975	0.025
K52.8 Other specified non-infective gastro-enteritis and colitis	0.022	0.976	0.001
J30.2 Other seasonal allergic rhinitis	0.000	0.979	0.021
J30.4 Allergic rhinitis, unspecified	0.000	0.980	0.020
J30.0 Vasomotor rhinitis	0.000	0.980	0.019
J31.0 Chronic rhinitis	0.000	0.981	0.019
G30 Alzheimer's disease	0.019	0.981	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.982	0.018
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.017	0.983	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.983	0.017
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.985	0.015
G30.1 Alzheimer's disease with late onset	0.015	0.985	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.015	0.985	0.000
D25 Leiomyoma of uterus	0.000	0.985	0.015
J30.3 Other allergic rhinitis	0.000	0.985	0.014
O16 Unspecified maternal hypertension	0.000	0.986	0.014
G55.3 Nerve root and plexus compressions in other dorsopathies	0.014	0.986	0.000
G30.8 Other Alzheimer's disease	0.014	0.986	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.986	0.014
G30.0 Alzheimer's disease with early onset	0.013	0.986	0.000
O14.9 Preeclampsia, unspecified	0.000	0.987	0.013
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.013	0.987	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.987	0.013
H72 Perforation of tympanic membrane	0.012	0.988	0.000
H71 Cholesteatoma of middle ear	0.012	0.988	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.012	0.988	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.012	0.988	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.011	0.988	0.000
O15 Eclampsia	0.000	0.989	0.011
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.989	0.011
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.989	0.011
J35.0 Chronic tonsillitis	0.000	0.989	0.011
O12.0 Gestational oedema	0.000	0.989	0.011
H65-H75 Diseases of middle ear and mastoid	0.011	0.989	0.000
H74 Other disorders of middle ear and mastoid	0.011	0.989	0.000
O12.1 Gestational proteinuria	0.000	0.990	0.010
O14.2 HELLP syndrome	0.000	0.990	0.010
O14.0 Moderate preeclampsia	0.000	0.990	0.010
O14.1 Severe preeclampsia	0.000	0.990	0.010
H72.2 Other marginal perforations of tympanic membrane	0.010	0.990	0.000
H74.1 Adhesive middle ear disease	0.010	0.990	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.990	0.009
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.991	0.009
K35 Acute appendicitis	0.000	0.991	0.009
K35.8 Acute appendicitis, other and unspecified	0.000	0.991	0.009
H72.0 Central perforation of tympanic membrane	0.009	0.991	0.000
H72.1 Attic perforation of tympanic membrane	0.009	0.991	0.000
H70 Mastoiditis and related conditions	0.009	0.991	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.992	0.008
O15.2 Eclampsia in the puerperium	0.000	0.992	0.008
O15.1 Eclampsia in labour	0.000	0.992	0.008
O15.0 Eclampsia in pregnancy	0.000	0.992	0.008
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.992	0.008
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.992	0.008
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.992	0.008
H66 Suppurative and unspecified otitis media	0.008	0.992	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.008	0.992	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.008	0.992	0.000
H68 Eustachian salpingitis and obstruction	0.008	0.992	0.000
H67 Otitis media in diseases classified elsewhere	0.008	0.992	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.992	0.008
J38.6 Stenosis of larynx	0.000	0.992	0.008
K35.3 Acute appendicitis with localized peritonitis	0.000	0.992	0.008
H74.3 Other acquired abnormalities of ear ossicles	0.007	0.992	0.000
J38.5 Laryngeal spasm	0.000	0.992	0.007
H74.4 Polyp of middle ear	0.007	0.993	0.000
H70.9 Mastoiditis, unspecified	0.007	0.993	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.007	0.993	0.000
H70.1 Chronic mastoiditis	0.006	0.993	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.993	0.000
H74.0 Tympanosclerosis	0.006	0.993	0.000
H70.8 Other mastoiditis and related conditions	0.006	0.994	0.000
H70.2 Petrositis	0.006	0.994	0.000
H70.0 Acute mastoiditis	0.006	0.994	0.000
H66.3 Other chronic suppurative otitis media	0.006	0.994	0.000
J38.2 Nodules of vocal cords	0.000	0.994	0.006
M47.2 Other spondylosis with radiculopathy	0.006	0.994	0.000
H66.4 Suppurative otitis media, unspecified	0.006	0.994	0.000
G30-G32 Other degenerative diseases of the nervous system	0.006	0.994	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.994	0.006
H65 Nonsuppurative otitis media	0.006	0.994	0.000
H66.0 Acute suppurative otitis media	0.006	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.006	0.994	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.006	0.994	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.006	0.994	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.006	0.994	0.000
H68.1 Obstruction of Eustachian tube	0.006	0.994	0.000
H68.0 Eustachian salpingitis	0.006	0.994	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.994	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
H73 Other disorders of tympanic membrane	0.006	0.994	0.000
K35-K38 Diseases of appendix	0.000	0.994	0.006
H69 Other disorders of Eustachian tube	0.005	0.994	0.000
R09.0 Asphyxia	0.006	0.994	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
K38 Other diseases of appendix	0.000	0.995	0.005
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.005	0.995	0.000
K38.1 Appendicular concretions	0.000	0.995	0.005
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.005	0.995	0.000
J34.3 Hypertrophy of nasal turbinates	0.000	0.995	0.005
K35.9 Acute appendicitis, unspecified	0.000	0.995	0.005
H65.0 Acute serous otitis media	0.005	0.995	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.005	0.995	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.005	0.995	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.005	0.995	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.005	0.995	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.005	0.995	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.005	0.995	0.000
H65.1 Other acute nonsuppurative otitis media	0.005	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.004	0.995	0.000
J38.7 Other diseases of larynx	0.000	0.995	0.004
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.004	0.995	0.000
J38.4 Oedema of larynx	0.000	0.995	0.004
H73.1 Chronic myringitis	0.004	0.996	0.000
H73.0 Acute myringitis	0.004	0.996	0.000
K37 Unspecified appendicitis	0.000	0.996	0.004
J38.3 Other diseases of vocal cords	0.000	0.996	0.004
K36 Other appendicitis	0.000	0.996	0.004
G70.0 Myasthenia gravis	0.004	0.996	0.000
K38.9 Disease of appendix, unspecified	0.000	0.996	0.004
H66.9 Otitis media, unspecified	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.004	0.996	0.000
H69.0 Patulous Eustachian tube	0.004	0.996	0.000
K38.3 Fistula of appendix	0.000	0.996	0.004
K38.2 Diverticulum of appendix	0.000	0.996	0.004
K38.0 Hyperplasia of appendix	0.000	0.996	0.004
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
K62.8 Other specified diseases of anus and rectum	0.004	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.996	0.004
E21.0 Primary hyperparathyroidism	0.004	0.996	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.004	0.996	0.000
K56.6 Other and unspecified intestinal obstruction	0.004	0.996	0.000
H65.4 Other chronic nonsuppurative otitis media	0.004	0.996	0.000
H69.8 Other specified disorders of Eustachian tube	0.003	0.996	0.000
K38.8 Other specified diseases of appendix	0.000	0.996	0.004
D25.0 Submucous leiomyoma of uterus	0.000	0.997	0.003
J38.0 Paralysis of vocal cords and larynx	0.001	0.997	0.003
G70 Myasthenia gravis and other myoneural disorders	0.003	0.997	0.000
G70.9 Myoneural disorder, unspecified	0.003	0.997	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
A04.5 Campylobacter enteritis	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.000	0.997	0.003
R09.1 Pleurisy	0.003	0.997	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.003	0.997	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.997	0.001
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
E10.4 With neurological complications	0.000	0.997	0.003
R09.2 Respiratory arrest	0.003	0.997	0.000
J38.1 Polyp of vocal cord and larynx	0.001	0.997	0.002
L84 Corns and callosities	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.000	0.997	0.003
G31.2 Degeneration of nervous system due to alcohol	0.003	0.997	0.000
G70.8 Other specified myoneural disorders	0.003	0.997	0.000
G70.2 Congenital and developmental myasthenia	0.003	0.997	0.000
G70.1 Toxic myoneural disorders	0.003	0.997	0.000
L03.0 Cellulitis of finger and toe	0.000	0.997	0.003
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.997	0.000
N04.9 Unspecified	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
E10.9 Without complications	0.000	0.997	0.003
G62.9 Polyneuropathy, unspecified	0.000	0.997	0.003
K29.5 Chronic gastritis, unspecified	0.000	0.997	0.003
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
Y83.3 Surgical operation with formation of external stoma	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
E10.0 With coma	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
E10.7 With multiple complications	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
D41.0 Kidney	0.000	0.998	0.002
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.002	0.998	0.000
C92 Myeloid leukaemia	0.002	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
E10.6 With other specified complications	0.000	0.998	0.002
C08.9 Major salivary gland, unspecified	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
E10.8 With unspecified complications	0.000	0.998	0.002
N04 Nephrotic syndrome	0.002	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
C08.0 Submandibular gland	0.002	0.998	0.000
R09.3 Abnormal sputum	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.001	0.998	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.002	0.998	0.000
C92.9 Myeloid leukaemia, unspecified	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
E10.2 With renal complications	0.000	0.998	0.002
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.998	0.002
N04.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.002	0.998	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.002	0.998	0.000
C92.5 Acute myelomonocytic leukaemia	0.002	0.998	0.000
C92.3 Myeloid sarcoma	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.998	0.002
C04.9 Floor of mouth, unspecified	0.002	0.998	0.000
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
C50.2 Upper-inner quadrant of breast	0.000	0.998	0.002
R90.0 Intracranial space-occupying lesion	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
N04.8 Other	0.001	0.998	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.001	0.998	0.000
N04.6 Dense deposit disease	0.001	0.998	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.998	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.998	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.998	0.000
N04.2 Diffuse membranous glomerulonephritis	0.001	0.998	0.000
N04.0 Minor glomerular abnormality	0.001	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
Z94.0 Kidney transplant status	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.002	0.998	0.000
I21 Acute myocardial infarction	0.000	0.998	0.002
G70-G73 Diseases of myoneural junction and muscle	0.002	0.998	0.000
C08.8 Overlapping lesion of major salivary glands	0.001	0.998	0.000
C08.1 Sublingual gland	0.001	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.001	0.998	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.998	0.002
C03.1 Lower gum	0.001	0.998	0.000
C11.9 Nasopharynx, unspecified	0.001	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.001	0.998	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.001	0.998	0.000
Z99.4 Dependence on artificial heart	0.001	0.998	0.000
Z99.0 Dependence on aspirator	0.001	0.998	0.000
C04 Malignant neoplasm of floor of mouth	0.002	0.998	0.000
T42.1 Iminostilbenes	0.001	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.998	0.000
T46.1 Calcium-channel blockers	0.001	0.998	0.000
T36 Poisoning by systemic antibiotics	0.001	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.001	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
C11 Malignant neoplasm of nasopharynx	0.001	0.998	0.000
C03 Malignant neoplasm of gum	0.001	0.998	0.000
G62 Other polyneuropathies	0.000	0.998	0.001
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.001	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.001
B19.9 Unspecified viral hepatitis without coma	0.001	0.998	0.000
F05.9 Delirium, unspecified	0.001	0.999	0.000
U80.0 Penicillin resistant agent	0.000	0.999	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.999	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.001	0.999	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.001	0.999	0.000
H11.3 Conjunctival haemorrhage	0.000	0.999	0.001
N08.3 Glomerular disorders in diabetes mellitus	0.001	0.999	0.000
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.999	0.000
T37.5 Antiviral drugs	0.001	0.999	0.000
T37.4 Anthelminthics	0.001	0.999	0.000
T37.3 Other antiprotozoal drugs	0.001	0.999	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.999	0.000
T37.1 Antimycobacterial drugs	0.001	0.999	0.000
T37.0 Sulphonamides	0.001	0.999	0.000
C00 Malignant neoplasm of lip	0.001	0.999	0.000
Z94 Transplanted organ and tissue status	0.001	0.999	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.999	0.001
K22.8 Other specified diseases of oesophagus	0.000	0.999	0.001
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.001	0.999	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
T36.0 Penicillins	0.001	0.999	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.999	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.001	0.999	0.000
C00.1 External lower lip	0.001	0.999	0.000
C04.8 Overlapping lesion of floor of mouth	0.001	0.999	0.000
C04.1 Lateral floor of mouth	0.001	0.999	0.000
C04.0 Anterior floor of mouth	0.001	0.999	0.000
K73.9 Chronic hepatitis, unspecified	0.001	0.999	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.001	0.999	0.000
Z94.4 Liver transplant status	0.001	0.999	0.000
Z94.1 Heart transplant status	0.001	0.999	0.000
C01 Malignant neoplasm of base of tongue	0.001	0.999	0.000
I07 Rheumatic tricuspid valve diseases	0.001	0.999	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.001	0.999	0.000
T36.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
T36.8 Other systemic antibiotics	0.001	0.999	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.999	0.000
T36.6 Rifamycins	0.001	0.999	0.000
T36.5 Aminoglycosides	0.001	0.999	0.000
T36.4 Tetracyclines	0.001	0.999	0.000
T36.3 Macrolides	0.001	0.999	0.000
T36.2 Chloramphenicol group	0.001	0.999	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.999	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.999	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
T44.0 Anticholinesterase agents	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
C10 Malignant neoplasm of oropharynx	0.001	0.999	0.000
C07 Malignant neoplasm of parotid gland	0.001	0.999	0.000
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
C03.9 Gum, unspecified	0.001	0.999	0.000
C03.0 Upper gum	0.001	0.999	0.000
C11.8 Overlapping lesion of nasopharynx	0.001	0.999	0.000
C11.3 Anterior wall of nasopharynx	0.001	0.999	0.000
C11.2 Lateral wall of nasopharynx	0.001	0.999	0.000
C11.1 Posterior wall of nasopharynx	0.001	0.999	0.000
C11.0 Superior wall of nasopharynx	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.000	0.999	0.001
I24.8 Other forms of acute ischaemic heart disease	0.000	0.999	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
C12 Malignant neoplasm of pyriform sinus	0.001	0.999	0.000
G71 Primary disorders of muscles	0.001	0.999	0.000
L43 Lichen planus	0.000	0.999	0.001
Q66 Congenital deformities of feet	0.001	0.999	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.001	0.999	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.999	0.001
G62.1 Alcoholic polyneuropathy	0.000	0.999	0.001
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.001	0.999	0.000
N99.1 Postprocedural urethral stricture	0.001	0.999	0.000
T41.5 Therapeutic gases	0.001	0.999	0.000
T41.4 Anaesthetic, unspecified	0.001	0.999	0.000
T41.3 Local anaesthetics	0.001	0.999	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.999	0.000
T41.1 Intravenous anaesthetics	0.001	0.999	0.000
T41.0 Inhaled anaesthetics	0.001	0.999	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
T48.5 Anti-common-cold drugs	0.001	0.999	0.000
T48.4 Expectorants	0.001	0.999	0.000
T48.3 Antitussives	0.001	0.999	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
T48.0 Oxytocic drugs	0.001	0.999	0.000
T49.9 Topical agent, unspecified	0.001	0.999	0.000
T49.8 Other topical agents	0.001	0.999	0.000
T49.7 Dental drugs, topically applied	0.001	0.999	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.999	0.000
T49.2 Local astringents and local detergents	0.001	0.999	0.000
T49.1 Antipruritics	0.001	0.999	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
Z46.8 Fitting and adjustment of other specified devices	0.001	0.999	0.000
C13 Malignant neoplasm of hypopharynx	0.001	0.999	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.001	0.999	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.001	0.999	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.999	0.001
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.001	0.999	0.000
G72 Other myopathies	0.001	0.999	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.001	0.999	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.001	0.999	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.001	0.999	0.000
T40.8 Lysergide [LSD]	0.001	0.999	0.000
T40.7 Cannabis (derivatives)	0.001	0.999	0.000
T40.5 Cocaine	0.001	0.999	0.000
T40.3 Methadone	0.001	0.999	0.000
T40.1 Heroin	0.001	0.999	0.000
T40.0 Opium	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.4 Other laxatives	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
T47.2 Stimulant laxatives	0.001	0.999	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations