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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs55816310
log Bayes Factor = 1.74282
Chromosome 10   position 134,832,927  (GRCh37) Explore rs55816310 on Ensembl!
Variant rs55816310 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.982 0.018 0.000
Chapter XXI Factors influencing health status and contact with health services
0.960 0.040 0.000
Chapter IX Diseases of the circulatory system
0.958 0.042 0.000
Chapter II Neoplasms
0.924 0.076 0.000
I10-I15 Hypertensive diseases
0.905 0.095 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.903 0.097 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.893 0.107 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.871 0.129 0.000
Chapter XI Diseases of the digestive system
0.870 0.130 0.000
I10 Essential (primary) hypertension
0.867 0.133 0.000
Chapter XIV Diseases of the genitourinary system
0.859 0.141 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.859 0.141 0.000
C50-C50 Malignant neoplasm of breast
0.851 0.149 0.000
I30-I52 Other forms of heart disease
0.830 0.170 0.000
C50 Malignant neoplasm of breast
0.799 0.201 0.000
Chapter X Diseases of the respiratory system
0.795 0.205 0.000
Chapter V Mental and behavioural disorders
0.791 0.209 0.000
Z85 Personal history of malignant neoplasm
0.790 0.210 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.785 0.215 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.775 0.225 0.000
R50-R69 General symptoms and signs
0.773 0.227 0.000
Chapter I Certain infectious and parasitic diseases
0.767 0.233 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.754 0.246 0.000
I20-I25 Ischaemic heart diseases
0.752 0.248 0.000
E70-E90 Metabolic disorders
0.750 0.250 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.749 0.251 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.749 0.251 0.000
Z86 Personal history of certain other diseases
0.749 0.251 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.746 0.254 0.000
R30-R39 Symptoms and signs involving the urinary system
0.741 0.259 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.739 0.261 0.000
C50.9 Breast, unspecified
0.738 0.262 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.734 0.266 0.000
Z51 Other medical care
0.734 0.266 0.000
Z42 Follow-up care involving plastic surgery
0.729 0.271 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.723 0.277 0.000
Chapter VIII Diseases of the ear and mastoid process
0.722 0.278 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.716 0.284 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.711 0.289 0.000
D10-D36 Benign neoplasms
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.704 0.296 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.704 0.296 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.704 0.296 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.704 0.296 0.000
N40-N51 Diseases of male genital organs
0.703 0.297 0.000
E00-E07 Disorders of thyroid gland
0.701 0.299 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.700 0.300 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.699 0.301 0.000
K29 Gastritis and duodenitis
0.695 0.305 0.000
K55-K64 Other diseases of intestines
0.693 0.307 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.692 0.308 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.691 0.309 0.000
I47 Paroxysmal tachycardia
0.690 0.310 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.689 0.311 0.000
C60-C63 Malignant neoplasms of male genital organs
0.688 0.312 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.686 0.313 0.000
I60-I69 Cerebrovascular diseases
0.686 0.313 0.000
I05-I09 Chronic rheumatic heart diseases
0.686 0.313 0.000
I00-I02 Acute rheumatic fever
0.686 0.313 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.677 0.323 0.000
Z92 Personal history of medical treatment
0.676 0.324 0.000
I35 Nonrheumatic aortic valve disorders
0.676 0.324 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.672 0.327 0.000
Chapter VI Diseases of the nervous system
0.668 0.332 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.668 0.332 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.665 0.335 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.663 0.337 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.662 0.337 0.000
D00-D09 In situ neoplasms
0.662 0.337 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.662 0.337 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.662 0.337 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.662 0.337 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.662 0.337 0.000
C64-C68 Malignant neoplasms of urinary tract
0.662 0.337 0.000
C51-C58 Malignant neoplasms of female genital organs
0.662 0.337 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.662 0.337 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.662 0.337 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.662 0.337 0.000
C15-C26 Malignant neoplasms of digestive organs
0.662 0.337 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.662 0.337 0.000
Chapter VII Diseases of the eye and adnexa
0.662 0.338 0.000
Z72 Problems related to lifestyle
0.660 0.340 0.000
Z50 Care involving use of rehabilitation procedures
0.660 0.340 0.000
C50.4 Upper-outer quadrant of breast
0.660 0.340 0.000
Z86.4 Personal history of psychoactive substance abuse
0.659 0.341 0.000
Z90.1 Acquired absence of breast(s)
0.657 0.343 0.000
E10-E14 Diabetes mellitus
0.657 0.343 0.000
Chapter XX External causes of morbidity and mortality
0.650 0.350 0.000
J40-J47 Chronic lower respiratory diseases
0.650 0.350 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.650 0.350 0.000
I15 Secondary hypertension
0.649 0.351 0.000
I13 Hypertensive heart and renal disease
0.649 0.351 0.000
I12 Hypertensive renal disease
0.649 0.351 0.000
I11 Hypertensive heart disease
0.649 0.351 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.648 0.352 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.647 0.352 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.647 0.352 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.647 0.352 0.000
R47-R49 Symptoms and signs involving speech and voice
0.647 0.352 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.647 0.352 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.647 0.352 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.643 0.357 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.643 0.357 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.640 0.360 0.000
Z98 Other postsurgical states
0.640 0.360 0.000
Z97 Presence of other devices
0.640 0.360 0.000
Z94 Transplanted organ and tissue status
0.640 0.360 0.000
Z93 Artificial opening status
0.640 0.360 0.000
Z89 Acquired absence of limb
0.640 0.360 0.000
Z84 Family history of other conditions
0.640 0.360 0.000
Z83 Family history of other specific disorders
0.640 0.360 0.000
Z81 Family history of mental and behavioural disorders
0.640 0.360 0.000
R42 Dizziness and giddiness
0.639 0.361 0.000
K50-K52 Noninfective enteritis and colitis
0.636 0.364 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.636 0.364 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.636 0.364 0.000
Z87 Personal history of other diseases and conditions
0.634 0.366 0.000
K29.8 Duodenitis
0.634 0.366 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.633 0.367 0.000
N30-N39 Other diseases of urinary system
0.632 0.368 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.631 0.369 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.629 0.371 0.000
N81 Female genital prolapse
0.626 0.374 0.000
E50-E64 Other nutritional deficiencies
0.625 0.375 0.000
E40-E46 Malnutrition
0.625 0.375 0.000
E20-E35 Disorders of other endocrine glands
0.625 0.375 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.625 0.375 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.624 0.376 0.000
Z80 Family history of malignant neoplasm
0.624 0.376 0.000
K70-K77 Diseases of liver
0.624 0.376 0.000
K65-K67 Diseases of peritoneum
0.624 0.376 0.000
K35-K38 Diseases of appendix
0.624 0.376 0.000
J09-J18 Influenza and pneumonia
0.623 0.377 0.000
Z96 Presence of other functional implants
0.621 0.379 0.000
Z51.2 Other chemotherapy
0.618 0.382 0.000
R59 Enlarged lymph nodes
0.616 0.384 0.000
N99-N99 Other disorders of the genitourinary system
0.616 0.384 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.616 0.384 0.000
N60-N64 Disorders of breast
0.616 0.384 0.000
N25-N29 Other disorders of kidney and ureter
0.616 0.384 0.000
N20-N23 Urolithiasis
0.616 0.384 0.000
N10-N16 Renal tubulo-interstitial diseases
0.616 0.384 0.000
N00-N08 Glomerular diseases
0.616 0.384 0.000
Z54 Convalescence
0.616 0.384 0.000
Z52 Donors of organs and tissues
0.616 0.384 0.000
Z49 Care involving dialysis
0.616 0.384 0.000
Z48 Other surgical follow-up care
0.616 0.384 0.000
Z47 Other orthopaedic follow-up care
0.616 0.384 0.000
Z45 Adjustment and management of implanted device
0.616 0.384 0.000
Z44 Fitting and adjustment of external prosthetic device
0.616 0.384 0.000
Z43 Attention to artificial openings
0.616 0.384 0.000
Z41 Procedures for purposes other than remedying health state
0.616 0.384 0.000
Z40 Prophylactic surgery
0.616 0.384 0.000
R51 Headache
0.614 0.386 0.000
K90-K93 Other diseases of the digestive system
0.614 0.386 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.613 0.387 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.613 0.387 0.000
R53 Malaise and fatigue
0.611 0.388 0.000
M50-M54 Other dorsopathies
0.605 0.395 0.000
K40-K46 Hernia
0.603 0.396 0.000
Z46 Fitting and adjustment of other devices
0.603 0.397 0.000
E65-E68 Obesity and other hyperalimentation
0.602 0.397 0.000
E78.0 Pure hypercholesterolaemia
0.601 0.399 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.600 0.400 0.000
N17-N19 Renal failure
0.597 0.403 0.000
I52 Other heart disorders in diseases classified elsewhere
0.595 0.405 0.000
I51 Complications and ill-defined descriptions of heart disease
0.595 0.405 0.000
I50 Heart failure
0.595 0.405 0.000
I49 Other cardiac arrhythmias
0.595 0.405 0.000
I48 Atrial fibrillation and flutter
0.595 0.405 0.000
I46 Cardiac arrest
0.595 0.405 0.000
I45 Other conduction disorders
0.595 0.405 0.000
I44 Atrioventricular and left bundle-branch block
0.595 0.405 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.595 0.405 0.000
I42 Cardiomyopathy
0.595 0.405 0.000
I41 Myocarditis in diseases classified elsewhere
0.595 0.405 0.000
I40 Acute myocarditis
0.595 0.405 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.595 0.405 0.000
I37 Pulmonary valve disorders
0.595 0.405 0.000
I36 Nonrheumatic tricuspid valve disorders
0.595 0.405 0.000
I34 Nonrheumatic mitral valve disorders
0.595 0.405 0.000
I33 Acute and subacute endocarditis
0.595 0.405 0.000
I32 Pericarditis in diseases classified elsewhere
0.595 0.405 0.000
I31 Other diseases of pericardium
0.595 0.405 0.000
I30 Acute pericarditis
0.595 0.405 0.000
I38 Endocarditis, valve unspecified
0.595 0.405 0.000
M20-M25 Other joint disorders
0.592 0.408 0.000
N40 Hyperplasia of prostate
0.591 0.409 0.000
I25 Chronic ischaemic heart disease
0.590 0.409 0.000
I47.1 Supraventricular tachycardia
0.590 0.410 0.000
B95-B98 Bacterial, viral and other infectious agents
0.590 0.410 0.000
Z30 Contraceptive management
0.588 0.412 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.583 0.417 0.000
L60-L75 Disorders of skin appendages
0.582 0.418 0.000
E03 Other hypothyroidism
0.579 0.420 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.579 0.421 0.000
A00-A09 Intestinal infectious diseases
0.578 0.422 0.000
R31 Unspecified haematuria
0.577 0.423 0.000
I84 Haemorrhoids
0.576 0.424 0.000
R55 Syncope and collapse
0.576 0.424 0.000
Z51.1 Chemotherapy session for neoplasm
0.574 0.426 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.574 0.426 0.000
C50.8 Overlapping lesion of breast
0.573 0.427 0.000
C50.6 Axillary tail of breast
0.573 0.427 0.000
C50.5 Lower-outer quadrant of breast
0.573 0.427 0.000
C50.3 Lower-inner quadrant of breast
0.573 0.427 0.000
C50.2 Upper-inner quadrant of breast
0.573 0.427 0.000
C50.1 Central portion of breast
0.573 0.427 0.000
C50.0 Nipple and areola
0.573 0.427 0.000
M80-M85 Disorders of bone density and structure
0.573 0.427 0.000
Z86.0 Personal history of other neoplasms
0.572 0.428 0.000
K22 Other diseases of oesophagus
0.570 0.430 0.000
J95-J99 Other diseases of the respiratory system
0.570 0.430 0.000
J90-J94 Other diseases of pleura
0.570 0.430 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.570 0.430 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.570 0.430 0.000
J60-J70 Lung diseases due to external agents
0.570 0.430 0.000
J30-J39 Other diseases of upper respiratory tract
0.570 0.430 0.000
J00-J06 Acute upper respiratory infections
0.570 0.430 0.000
F30-F39 Mood [affective] disorders
0.569 0.430 0.000
M70-M79 Other soft tissue disorders
0.568 0.432 0.000
F99-F99 Unspecified mental disorder
0.567 0.433 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.567 0.433 0.000
F80-F89 Disorders of psychological development
0.567 0.433 0.000
F70-F79 Mental retardation
0.567 0.433 0.000
F60-F69 Disorders of adult personality and behaviour
0.567 0.433 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.567 0.433 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.567 0.433 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.567 0.433 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.566 0.433 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.566 0.433 0.000
Z85.6 Personal history of leukaemia
0.566 0.433 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.566 0.433 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.566 0.433 0.000
Z72.1 Alcohol use
0.566 0.434 0.000
R33 Retention of urine
0.566 0.434 0.000
K31 Other diseases of stomach and duodenum
0.566 0.434 0.000
I35.0 Aortic (valve) stenosis
0.565 0.434 0.000
Z76 Persons encountering health services in other circumstances
0.563 0.437 0.000
Z75 Problems related to medical facilities and other health care
0.563 0.437 0.000
Z74 Problems related to care-provider dependency
0.563 0.437 0.000
Z73 Problems related to life-management difficulty
0.563 0.437 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.563 0.437 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.563 0.437 0.000
N92 Excessive, frequent and irregular menstruation
0.561 0.439 0.000
R39 Other symptoms and signs involving the urinary system
0.561 0.439 0.000
K57 Diverticular disease of intestine
0.559 0.440 0.000
K29.7 Gastritis, unspecified
0.559 0.441 0.000
M05-M14 Inflammatory polyarthropathies
0.558 0.442 0.000
R50 Fever of unknown origin
0.557 0.443 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.557 0.443 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.555 0.445 0.000
M91-M94 Chondropathies
0.555 0.445 0.000
M86-M90 Other osteopathies
0.555 0.445 0.000
M65-M68 Disorders of synovium and tendon
0.555 0.445 0.000
M60-M63 Disorders of muscles
0.555 0.445 0.000
M45-M49 Spondylopathies
0.555 0.445 0.000
M40-M43 Deforming dorsopathies
0.555 0.445 0.000
M00-M03 Infectious arthropathies
0.555 0.445 0.000
R68 Other general symptoms and signs
0.555 0.445 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.555 0.445 0.000
R62 Lack of expected normal physiological development
0.555 0.445 0.000
R61 Hyperhidrosis
0.555 0.445 0.000
R60 Oedema, not elsewhere classified
0.555 0.445 0.000
R57 Shock, not elsewhere classified
0.555 0.445 0.000
R56 Convulsions, not elsewhere classified
0.555 0.445 0.000
R52 Pain, not elsewhere classified
0.555 0.445 0.000
R64 Cachexia
0.555 0.445 0.000
R58 Haemorrhage, not elsewhere classified
0.555 0.445 0.000
R54 Senility
0.555 0.445 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.554 0.446 0.000
I21 Acute myocardial infarction
0.551 0.449 0.000
B99-B99 Other infectious diseases
0.550 0.450 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.550 0.450 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.550 0.450 0.000
B65-B83 Helminthiases
0.550 0.450 0.000
B50-B64 Protozoal diseases
0.550 0.450 0.000
B35-B49 Mycoses
0.550 0.450 0.000
B25-B34 Other viral diseases
0.550 0.450 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.550 0.450 0.000
B15-B19 Viral hepatitis
0.550 0.450 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.550 0.450 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.550 0.450 0.000
A80-A89 Viral infections of the central nervous system
0.550 0.450 0.000
A75-A79 Rickettsioses
0.550 0.450 0.000
A70-A74 Other diseases caused by chlamydiae
0.550 0.450 0.000
A65-A69 Other spirochaetal diseases
0.550 0.450 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.550 0.450 0.000
A30-A49 Other bacterial diseases
0.550 0.450 0.000
A20-A28 Certain zoonotic bacterial diseases
0.550 0.450 0.000
A15-A19 Tuberculosis
0.550 0.450 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.550 0.450 0.000
R63 Symptoms and signs concerning food and fluid intake
0.549 0.450 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.549 0.451 0.000
D50-D53 Nutritional anaemias
0.548 0.451 0.000
R11 Nausea and vomiting
0.548 0.452 0.000
I20 Angina pectoris
0.547 0.453 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.546 0.454 0.000
C77.3 Axillary and upper limb lymph nodes
0.546 0.454 0.000
C80 Malignant neoplasm without specification of site
0.541 0.459 0.000
C79 Secondary malignant neoplasm of other sites
0.541 0.459 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.541 0.459 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.541 0.459 0.000
I24 Other acute ischaemic heart diseases
0.539 0.460 0.000
I23 Certain current complications following acute myocardial infarction
0.539 0.460 0.000
I22 Subsequent myocardial infarction
0.539 0.460 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.538 0.462 0.000
E88 Other metabolic disorders
0.538 0.462 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.538 0.462 0.000
E85 Amyloidosis
0.538 0.462 0.000
E84 Cystic fibrosis
0.538 0.462 0.000
E83 Disorders of mineral metabolism
0.538 0.462 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.538 0.462 0.000
E79 Disorders of purine and pyrimidine metabolism
0.538 0.462 0.000
E77 Disorders of glycoprotein metabolism
0.538 0.462 0.000
E76 Disorders of glycosaminoglycan metabolism
0.538 0.462 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.538 0.462 0.000
E74 Other disorders of carbohydrate metabolism
0.538 0.462 0.000
E73 Lactose intolerance
0.538 0.462 0.000
E72 Other disorders of amino-acid metabolism
0.538 0.462 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.538 0.462 0.000
E70 Disorders of aromatic amino-acid metabolism
0.538 0.462 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.538 0.462 0.000
E86 Volume depletion
0.538 0.462 0.000
R46 Symptoms and signs involving appearance and behaviour
0.537 0.463 0.000
R45 Symptoms and signs involving emotional state
0.537 0.463 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.537 0.463 0.000
R43 Disturbances of smell and taste
0.537 0.463 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.537 0.463 0.000
R40 Somnolence, stupor and coma
0.537 0.463 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.537 0.463 0.000
K28 Gastrojejunal ulcer
0.537 0.463 0.000
K27 Peptic ulcer, site unspecified
0.537 0.463 0.000
K26 Duodenal ulcer
0.537 0.463 0.000
K25 Gastric ulcer
0.537 0.463 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.537 0.463 0.000
D17 Benign lipomatous neoplasm
0.537 0.463 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.537 0.463 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.537 0.463 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.537 0.463 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.537 0.463 0.000
H90-H95 Other disorders of ear
0.536 0.464 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.535 0.465 0.000
L50-L54 Urticaria and erythema
0.535 0.465 0.000
L40-L45 Papulosquamous disorders
0.535 0.465 0.000
L20-L30 Dermatitis and eczema
0.535 0.465 0.000
L10-L14 Bullous disorders
0.535 0.465 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.534 0.466 0.000
R30 Pain associated with micturition
0.531 0.469 0.000
R36 Urethral discharge
0.531 0.469 0.000
R35 Polyuria
0.531 0.469 0.000
R34 Anuria and oliguria
0.531 0.469 0.000
R32 Unspecified urinary incontinence
0.531 0.469 0.000
Z90.8 Acquired absence of other organs
0.530 0.470 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.530 0.470 0.000
Z90.5 Acquired absence of kidney
0.530 0.470 0.000
Z90.3 Acquired absence of part of stomach
0.530 0.470 0.000
Z90.2 Acquired absence of lung [part of]
0.530 0.470 0.000
Z90.0 Acquired absence of part of head and neck
0.530 0.470 0.000
K30 Dyspepsia
0.529 0.471 0.000
Z39 Postpartum care and examination
0.526 0.473 0.000
Z38 Liveborn infants according to place of birth
0.526 0.473 0.000
Z36 Antenatal screening
0.526 0.473 0.000
Z35 Supervision of high-risk pregnancy
0.526 0.473 0.000
Z34 Supervision of normal pregnancy
0.526 0.473 0.000
Z32 Pregnancy examination and test
0.526 0.473 0.000
Z31 Procreative management
0.526 0.473 0.000
Z33 Pregnant state, incidental
0.526 0.473 0.000
J45 Asthma
0.526 0.473 0.000
Z51.9 Medical care, unspecified
0.526 0.474 0.000
Z51.8 Other specified medical care
0.526 0.474 0.000
Z51.6 Desensitisation to allergens
0.526 0.474 0.000
Z51.5 Palliative care
0.526 0.474 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.526 0.474 0.000
Z51.3 Blood transfusion without reported diagnosis
0.526 0.474 0.000
Z51.0 Radiotherapy session
0.526 0.474 0.000
J20-J22 Other acute lower respiratory infections
0.525 0.475 0.000
K63 Other diseases of intestine
0.524 0.476 0.000
K59 Other functional intestinal disorders
0.523 0.477 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.522 0.477 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.522 0.477 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.522 0.477 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.522 0.477 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.522 0.477 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.522 0.477 0.000
K82 Other diseases of gallbladder
0.520 0.480 0.000
C61 Malignant neoplasm of prostate
0.519 0.481 0.000
N98 Complications associated with artificial fertilisation
0.519 0.481 0.000
N97 Female infertility
0.519 0.481 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.519 0.481 0.000
N93 Other abnormal uterine and vaginal bleeding
0.519 0.481 0.000
N91 Absent, scanty and rare menstruation
0.519 0.481 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.519 0.481 0.000
N89 Other noninflammatory disorders of vagina
0.519 0.481 0.000
N88 Other noninflammatory disorders of cervix uteri
0.519 0.481 0.000
N87 Dysplasia of cervix uteri
0.519 0.481 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.519 0.481 0.000
N82 Fistulae involving female genital tract
0.519 0.481 0.000
N80 Endometriosis
0.519 0.481 0.000
N96 Habitual aborter
0.519 0.481 0.000
N86 Erosion and ectropion of cervix uteri
0.519 0.481 0.000
H80-H83 Diseases of inner ear
0.518 0.482 0.000
H65-H75 Diseases of middle ear and mastoid
0.518 0.482 0.000
H60-H62 Diseases of external ear
0.518 0.482 0.000
Z50.1 Other physical therapy
0.517 0.483 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.513 0.486 0.000
I88 Nonspecific lymphadenitis
0.513 0.486 0.000
I87 Other disorders of veins
0.513 0.486 0.000
I86 Varicose veins of other sites
0.513 0.486 0.000
I85 Oesophageal varices
0.513 0.486 0.000
I82 Other venous embolism and thrombosis
0.513 0.486 0.000
I80 Phlebitis and thrombophlebitis
0.513 0.486 0.000
I81 Portal vein thrombosis
0.513 0.486 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.514 0.486 0.000
N81.1 Cystocele
0.513 0.487 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.512 0.487 0.000
K42 Umbilical hernia
0.511 0.489 0.000
R69 Unknown and unspecified causes of morbidity
0.511 0.489 0.000
R94 Abnormal results of function studies
0.510 0.490 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.510 0.490 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.510 0.490 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.510 0.490 0.000
D36 Benign neoplasm of other and unspecified sites
0.510 0.490 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.510 0.490 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.510 0.490 0.000
D32 Benign neoplasm of meninges
0.510 0.490 0.000
D31 Benign neoplasm of eye and adnexa
0.510 0.490 0.000
D30 Benign neoplasm of urinary organs
0.510 0.490 0.000
D29 Benign neoplasm of male genital organs
0.510 0.490 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.510 0.490 0.000
D26 Other benign neoplasms of uterus
0.510 0.490 0.000
D23 Other benign neoplasms of skin
0.510 0.490 0.000
D22 Melanocytic naevi
0.510 0.490 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.510 0.490 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.510 0.490 0.000
D19 Benign neoplasm of mesothelial tissue
0.510 0.490 0.000
D18 Haemangioma and lymphangioma, any site
0.510 0.490 0.000
D16 Benign neoplasm of bone and articular cartilage
0.510 0.490 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.510 0.490 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.510 0.490 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.510 0.490 0.000
D11 Benign neoplasm of major salivary glands
0.510 0.490 0.000
D10 Benign neoplasm of mouth and pharynx
0.510 0.490 0.000
D34 Benign neoplasm of thyroid gland
0.510 0.490 0.000
D27 Benign neoplasm of ovary
0.510 0.490 0.000
D24 Benign neoplasm of breast
0.510 0.490 0.000
K29.6 Other gastritis
0.509 0.491 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.509 0.491 0.000
Z92.3 Personal history of irradiation
0.508 0.492 0.000
M15-M19 Arthrosis
0.505 0.494 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.505 0.495 0.000
O85-O92 Complications predominantly related to the puerperium
0.505 0.495 0.000
O80-O84 Delivery
0.505 0.495 0.000
O60-O75 Complications of labour and delivery
0.505 0.495 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.505 0.495 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.505 0.495 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.505 0.495 0.000
O00-O08 Pregnancy with abortive outcome
0.505 0.495 0.000
P90-P96 Other disorders originating in the perinatal period
0.505 0.495 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.505 0.495 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.505 0.495 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.505 0.495 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.505 0.495 0.000
P35-P39 Infections specific to the perinatal period
0.505 0.495 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.505 0.495 0.000
P10-P15 Birth trauma
0.505 0.495 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.505 0.495 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.505 0.495 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.505 0.495 0.000
Q80-Q89 Other congenital malformations
0.505 0.495 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.505 0.495 0.000
Q60-Q64 Congenital malformations of the urinary system
0.505 0.495 0.000
Q50-Q56 Congenital malformations of genital organs
0.505 0.495 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.505 0.495 0.000
Q35-Q37 Cleft lip and cleft palate
0.505 0.495 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.505 0.495 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.505 0.495 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.505 0.495 0.000
Q00-Q07 Congenital malformations of the nervous system
0.505 0.495 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.505 0.495 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.505 0.495 0.000
J43 Emphysema
0.504 0.496 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.504 0.496 0.000
N50 Other disorders of male genital organs
0.504 0.496 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.504 0.496 0.000
N48 Other disorders of penis
0.504 0.496 0.000
N45 Orchitis and epididymitis
0.504 0.496 0.000
N43 Hydrocele and spermatocele
0.504 0.496 0.000
N42 Other disorders of prostate
0.504 0.496 0.000
N41 Inflammatory diseases of prostate
0.504 0.496 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.504 0.496 0.000
N46 Male infertility
0.504 0.496 0.000
N44 Torsion of testis
0.504 0.496 0.000
R59.0 Localised enlarged lymph nodes
0.504 0.496 0.000
Z37 Outcome of delivery
0.503 0.496 0.000
E07 Other disorders of thyroid
0.503 0.497 0.000
E06 Thyroiditis
0.503 0.497 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.503 0.497 0.000
E04 Other non-toxic goitre
0.503 0.497 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.503 0.497 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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