TreeWAS – Variant ID: rs56033260

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M54 Dorsalgia	1.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
M20-M25 Other joint disorders	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.995	0.005
B35-B49 Mycoses	0.995	0.005
M54.5 Low back pain	0.993	0.007
M23 Internal derangement of knee	0.987	0.013
B37 Candidiasis	0.986	0.014
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.984	0.016
M54.59 Low back pain (Site unspecified)	0.984	0.016
M54.9 Dorsalgia, unspecified	0.980	0.020
E70-E90 Metabolic disorders	0.972	0.028
M05-M14 Inflammatory polyarthropathies	0.970	0.030
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.968	0.032
T84.0 Mechanical complication of internal joint prosthesis	0.967	0.033
E87 Other disorders of fluid, electrolyte and acid-base balance	0.966	0.034
M23.8 Other internal derangements of knee	0.966	0.034
B37.0 Candidal stomatitis	0.961	0.039
B15-B19 Viral hepatitis	0.959	0.041
M06 Other rheumatoid arthritis	0.957	0.043
E87.6 Hypokalaemia	0.950	0.050
M06.9 Rheumatoid arthritis, unspecified	0.950	0.050
M65-M68 Disorders of synovium and tendon	0.947	0.053
B95-B98 Bacterial, viral and other infectious agents	0.944	0.056
Chapter XX External causes of morbidity and mortality	0.943	0.057
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.935	0.065
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.930	0.070
M35 Other systemic involvement of connective tissue	0.927	0.073
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.926	0.074
M54.96 Dorsalgia, unspecified (Lumbar region)	0.922	0.078
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.921	0.079
E50-E64 Other nutritional deficiencies	0.917	0.083
M23.5 Chronic instability of knee	0.916	0.084
T92 Sequelae of injuries of upper limb	0.911	0.089
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.906	0.094
E87.1 Hypo-osmolality and hyponatraemia	0.905	0.095
M86-M90 Other osteopathies	0.904	0.096
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.901	0.099
M54.99 Dorsalgia, unspecified (Site unspecified)	0.899	0.101
Chapter IX Diseases of the circulatory system	0.897	0.103
M40-M43 Deforming dorsopathies	0.896	0.104
M54.2 Cervicalgia	0.896	0.104
T91 Sequelae of injuries of neck and trunk	0.896	0.104
M22 Disorders of patella	0.895	0.105
B18 Chronic viral hepatitis	0.895	0.105
B37.9 Candidiasis, unspecified	0.893	0.107
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.882	0.118
T87 Complications peculiar to reattachment and amputation	0.878	0.122
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.872	0.127
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.871	0.129
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.869	0.131
E20-E35 Disorders of other endocrine glands	0.869	0.131
S90-S99 Injuries to the ankle and foot	0.868	0.132
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.868	0.132
M60-M63 Disorders of muscles	0.865	0.135
E10-E14 Diabetes mellitus	0.859	0.141
M54.1 Radiculopathy	0.858	0.141
B25-B34 Other viral diseases	0.857	0.143
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.855	0.145
M41 Scoliosis	0.848	0.152
M65 Synovitis and tenosynovitis	0.847	0.153
I05-I09 Chronic rheumatic heart diseases	0.846	0.154
M35.0 Sicca syndrome [Sjogren]	0.844	0.156
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.844	0.156
T85 Complications of other internal prosthetic devices, implants and grafts	0.843	0.157
I85 Oesophageal varices	0.840	0.160
M54.4 Lumbago with sciatica	0.840	0.160
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.839	0.161
M54.22 Cervicalgia (Cervical region)	0.839	0.161
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.839	0.161
E40-E46 Malnutrition	0.838	0.162
M54.3 Sciatica	0.838	0.162
M67 Other disorders of synovium and tendon	0.836	0.164
T20-T25 Burns and corrosions of external body surface, specified by site	0.834	0.166
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.834	0.166
Y83.1 Surgical operation with implant of artificial internal device	0.830	0.170
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.828	0.172
E14 Unspecified diabetes mellitus	0.828	0.172
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.827	0.173
M80-M85 Disorders of bone density and structure	0.824	0.176
S70-S79 Injuries to the hip and thigh	0.823	0.177
I82 Other venous embolism and thrombosis	0.815	0.185
M41.9 Scoliosis, unspecified	0.814	0.186
B20-B24 Human immunodeficiency virus [HIV] disease	0.813	0.186
B18.2 Chronic viral hepatitis C	0.813	0.187
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.812	0.188
E61 Deficiency of other nutrient elements	0.810	0.190
S10-S19 Injuries to the neck	0.809	0.191
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.808	0.192
M22.4 Chondromalacia patellae	0.806	0.194
I85.0 Oesophageal varices with bleeding	0.806	0.194
M24 Other specific joint derangements	0.805	0.195
M87 Osteonecrosis	0.803	0.197
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.803	0.197
I86 Varicose veins of other sites	0.802	0.198
E87.2 Acidosis	0.802	0.198
M07 Psoriatic and enteropathic arthropathies	0.800	0.200
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.794	0.206
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.793	0.207
E65-E68 Obesity and other hyperalimentation	0.792	0.208
B49 Unspecified mycosis	0.789	0.211
E53 Deficiency of other B group vitamins	0.788	0.212
B17 Other acute viral hepatitis	0.788	0.212
J44 Other chronic obstructive pulmonary disease	0.788	0.212
M25 Other joint disorders, not elsewhere classified	0.787	0.213
B35 Dermatophytosis	0.785	0.215
T84.1 Mechanical complication of internal fixation device of bones of limb	0.785	0.215
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.784	0.216
T82.3 Mechanical complication of other vascular grafts	0.783	0.217
M34 Systemic sclerosis	0.783	0.217
T00-T07 Injuries involving multiple body regions	0.783	0.217
B37.3 Candidiasis of vulva and vagina	0.782	0.218
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.781	0.219
A50-A64 Infections with a predominantly sexual mode of transmission	0.781	0.219
I08 Multiple valve diseases	0.781	0.219
M23.80 Other internal derangements of knee (Multiple sites)	0.779	0.221
S90 Superficial injury of ankle and foot	0.778	0.222
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.775	0.225
M30 Polyarteritis nodosa and related conditions	0.774	0.226
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.774	0.226
T15-T19 Effects of foreign body entering through natural orifice	0.773	0.227
E14.9 Without complications	0.773	0.227
Chapter X Diseases of the respiratory system	0.771	0.229
B44 Aspergillosis	0.770	0.230
M62 Other disorders of muscle	0.769	0.231
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.769	0.231
E87.3 Alkalosis	0.768	0.231
J40-J47 Chronic lower respiratory diseases	0.767	0.233
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.767	0.233
M00-M03 Infectious arthropathies	0.765	0.235
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.764	0.236
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.764	0.236
Y83.5 Amputation of limb(s)	0.763	0.237
T92.1 Sequelae of fracture of arm	0.762	0.237
M67.8 Other specified disorders of synovium and tendon	0.762	0.238
S20-S29 Injuries to the thorax	0.761	0.239
A65-A69 Other spirochaetal diseases	0.760	0.240
Chapter XXII Codes for special purposes	0.760	0.240
W50-W64 Exposure to animate mechanical forces	0.760	0.240
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.759	0.241
M41.99 Scoliosis, unspecified (Site unspecified)	0.759	0.241
M54.39 Sciatica (Site unspecified)	0.758	0.242
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.758	0.242
M54.55 Low back pain (Thoracolumbar region)	0.757	0.242
I82.2 Embolism and thrombosis of vena cava	0.757	0.243
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.754	0.246
T92.9 Sequelae of unspecified injury of upper limb	0.754	0.246
T85.2 Mechanical complication of intraocular lens	0.752	0.248
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.752	0.248
B18.1 Chronic viral hepatitis B without delta-agent	0.752	0.248
M89 Other disorders of bone	0.751	0.249
M91-M94 Chondropathies	0.750	0.249
T92.2 Sequelae of fracture at wrist and hand level	0.750	0.250
Y83.9 Surgical procedure, unspecified	0.750	0.250
B90-B94 Sequelae of infectious and parasitic diseases	0.749	0.250
B19 Unspecified viral hepatitis	0.746	0.254
M54.6 Pain in thoracic spine	0.746	0.254
J44.9 Chronic obstructive pulmonary disease, unspecified	0.746	0.254
T14 Injury of unspecified body region	0.746	0.254
T87.4 Infection of amputation stump	0.745	0.255
Q00-Q07 Congenital malformations of the nervous system	0.744	0.256
M65.3 Trigger finger	0.744	0.256
Q20-Q28 Congenital malformations of the circulatory system	0.744	0.256
E78.2 Mixed hyperlipidaemia	0.744	0.256
T91.2 Sequelae of other fracture of thorax and pelvis	0.744	0.256
M22.8 Other disorders of patella	0.744	0.256
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.744	0.256
T93 Sequelae of injuries of lower limb	0.744	0.256
I08.1 Disorders of both mitral and tricuspid valves	0.743	0.257
X58-X59 Accidental exposure to other and unspecified factors	0.742	0.258
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.742	0.258
M54.16 Radiculopathy (Lumbar region)	0.740	0.260
T81 Complications of procedures, not elsewhere classified	0.738	0.262
I86.4 Gastric varices	0.737	0.263
M45-M49 Spondylopathies	0.736	0.264
V01-V09 Pedestrian injured in transport accident	0.735	0.265
E61.1 Iron deficiency	0.733	0.267
Y60-Y69 Misadventures to patients during surgical and medical care	0.733	0.267
M35.3 Polymyalgia rheumatica	0.732	0.268
E14.3 With ophthalmic complications	0.732	0.268
T92.0 Sequelae of open wound of upper limb	0.731	0.269
B16 Acute hepatitis B	0.730	0.270
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.729	0.271
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.728	0.272
M87.9 Osteonecrosis, unspecified	0.727	0.273
T31 Burns classified according to extent of body surface involved	0.725	0.274
E22 Hyperfunction of pituitary gland	0.724	0.276
E46 Unspecified protein-energy malnutrition	0.723	0.277
M06.4 Inflammatory polyarthropathy	0.723	0.277
M84 Disorders of continuity of bone	0.722	0.278
T91.3 Sequelae of injury of spinal cord	0.722	0.278
T87.6 Other and unspecified complications of amputation stump	0.720	0.280
B37.8 Candidiasis of other sites	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M54.8 Other dorsalgia	0.717	0.283
M54.0 Panniculitis affecting regions of neck and back	0.717	0.283
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283
B50-B64 Protozoal diseases	0.717	0.283
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283
A75-A79 Rickettsioses	0.717	0.283
A70-A74 Other diseases caused by chlamydiae	0.717	0.283
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283
A15-A19 Tuberculosis	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.284
M33 Dermatopolymyositis	0.715	0.284
M32 Systemic lupus erythematosus	0.715	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.715	0.285
M23.6 Other spontaneous disruption of ligament(s) of knee	0.715	0.285
T91.9 Sequelae of unspecified injury of neck and trunk	0.715	0.285
B48 Other mycoses, not elsewhere classified	0.713	0.287
B47 Mycetoma	0.713	0.287
B46 Zygomycosis	0.713	0.287
B45 Cryptococcosis	0.713	0.287
B43 Chromomycosis and phaeomycotic abscess	0.713	0.287
B42 Sporotrichosis	0.713	0.287
B41 Paracoccidioidomycosis	0.713	0.287
B40 Blastomycosis	0.713	0.287
B39 Histoplasmosis	0.713	0.287
B38 Coccidioidomycosis	0.713	0.287
B36 Other superficial mycoses	0.713	0.287
Q50-Q56 Congenital malformations of genital organs	0.712	0.288
M54.54 Low back pain-Thoracic	0.712	0.288
M54.53 Low back pain-Cervicothoracic	0.712	0.288
M54.52 Low back pain-Cervical	0.712	0.288
M54.51 Low back pain-Occipit-atl-axl	0.712	0.288
I07 Rheumatic tricuspid valve diseases	0.710	0.290
M54.50 Low back pain (Multiple sites in spine)	0.709	0.290
B34 Viral infection of unspecified site	0.710	0.290
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.709	0.291
M50 Cervical disk disorders	0.708	0.292
M23.9 Internal derangement of knee, unspecified	0.707	0.293
M23.1 Discoid meniscus (congenital)	0.707	0.293
M23.0 Cystic meniscus	0.707	0.293
M35.1 Other overlap syndromes	0.707	0.293
B37.7 Candidal septicaemia	0.707	0.293
B37.6 Candidal endocarditis	0.707	0.293
B37.5 Candidal meningitis	0.707	0.293
B37.4 Candidiasis of other urogenital sites	0.707	0.293
B37.2 Candidiasis of skin and nail	0.707	0.293
B37.1 Pulmonary candidiasis	0.707	0.293
I70-I79 Diseases of arteries, arterioles and capillaries	0.707	0.293
M66 Spontaneous rupture of synovium and tendon	0.705	0.295
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.705	0.295
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.703	0.297
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.703	0.297
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.703	0.297
M54.94 Dorsalgia, unspecified (Thoracic region)	0.703	0.297
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.703	0.297
M54.92 Dorsalgia, unspecified (Cervical region)	0.703	0.297
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.703	0.297
I85.9 Oesophageal varices without bleeding	0.703	0.297
X20-X29 Contact with venomous animals and plants	0.702	0.298
Y00-Y09 Assault	0.702	0.298
X40-X49 Accidental poisoning by and exposure to noxious substances	0.701	0.299
X60-X84 Intentional self-harm	0.701	0.299
X10-X19 Contact with heat and hot substances	0.701	0.299
E87.7 Fluid overload	0.700	0.300
M62.8 Other specified disorders of muscle	0.700	0.300
T91.1 Sequelae of fracture of spine	0.699	0.301
I95-I99 Other and unspecified disorders of the circulatory system	0.699	0.301
S72 Fracture of femur	0.699	0.301
M23.4 Loose body in knee	0.699	0.301
E84 Cystic fibrosis	0.697	0.303
E79 Disorders of purine and pyrimidine metabolism	0.697	0.303
E77 Disorders of glycoprotein metabolism	0.697	0.303
E76 Disorders of glycosaminoglycan metabolism	0.697	0.303
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.697	0.303
E74 Other disorders of carbohydrate metabolism	0.697	0.303
E72 Other disorders of amino-acid metabolism	0.697	0.303
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.697	0.303
E70 Disorders of aromatic amino-acid metabolism	0.697	0.303
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.697	0.303
E53.8 Deficiency of other specified B group vitamins	0.696	0.304
M12 Other specific arthropathies	0.696	0.304
M09 Juvenile arthritis in diseases classified elsewhere	0.696	0.304
M08 Juvenile arthritis	0.696	0.304
T95 Sequelae of burns, corrosions and frostbite	0.694	0.306
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.694	0.306
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.694	0.306
E85 Amyloidosis	0.694	0.306
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.693	0.307
E87.4 Mixed disorder of acid-base balance	0.693	0.307
T98 Sequelae of other and unspecified effects of external causes	0.693	0.307
M23.87 Other internal derangements of knee (Capsular ligament)	0.693	0.307
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.693	0.307
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.693	0.307
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.693	0.307
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.692	0.308
T23 Burn and corrosion of wrist and hand	0.692	0.308
A80-A89 Viral infections of the central nervous system	0.691	0.309
S90.9 Superficial injury of ankle and foot, unspecified	0.689	0.311
M05 Seropositive rheumatoid arthritis	0.689	0.311
E73 Lactose intolerance	0.689	0.311
B25 Cytomegaloviral disease	0.688	0.312
B99-B99 Other infectious diseases	0.687	0.312
M06.8 Other specified rheumatoid arthritis	0.686	0.314
M06.3 Rheumatoid nodule	0.686	0.314
M06.2 Rheumatoid bursitis	0.686	0.314
M06.1 Adult-onset Still's disease	0.686	0.314
M22.3 Other derangements of patella	0.686	0.314
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.686	0.314
T88 Other complications of surgical and medical care, not elsewhere classified	0.685	0.315
M65.4 Radial styloid tenosynovitis [de Quervain]	0.685	0.315
M53 Other dorsopathies, not elsewhere classified	0.684	0.316
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.683	0.317
E34 Other endocrine disorders	0.682	0.317
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.682	0.318
T94 Sequelae of injuries involving multiple and unspecified body regions	0.682	0.318
M06.98 Rheumatoid arthritis, unspecified (Other)	0.681	0.319
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.681	0.319
B24 Unspecified human immunodeficiency virus [HIV] disease	0.680	0.320
Q38-Q45 Other congenital malformations of the digestive system	0.680	0.320
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.679	0.321
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.679	0.321
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.678	0.322
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.678	0.322
M07.3 Other psoriatic arthropathies	0.677	0.322
M54.46 Lumbago with sciatica (Lumbar region)	0.677	0.323
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.676	0.323
Y35-Y36 Legal intervention and operations of war	0.676	0.323
Y10-Y34 Event of undetermined intent	0.676	0.323
X85-X99 Assault	0.676	0.323
X30-X39 Exposure to forces of nature	0.676	0.323
X00-X09 Exposure to smoke, fire and flames	0.676	0.323
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.676	0.323
W75-W84 Other accidental threats to breathing	0.676	0.323
W65-W74 Accidental drowning and submersion	0.676	0.323
V98-V99 Other and unspecified transport accidents	0.676	0.323
V95-V97 Air and space transport accidents	0.676	0.323
V90-V94 Water transport accidents	0.676	0.323
V70-V79 Bus occupant injured in transport accident	0.676	0.323
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.676	0.323
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.676	0.323
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.676	0.323
M41.96 Scoliosis, unspecified (Lumbar region)	0.676	0.324
M24.8 Other specific joint derangements, not elsewhere classified	0.675	0.325
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.675	0.325
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.673	0.327
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.673	0.327
M31 Other necrotising vasculopathies	0.672	0.328
M65.34 Trigger finger-Hand	0.671	0.329
Q80-Q89 Other congenital malformations	0.671	0.329
M54.19 Radiculopathy (Site unspecified)	0.670	0.329
M23.2 Derangement of meniscus due to old tear or injury	0.670	0.330
B15 Acute hepatitis A	0.669	0.331
E26 Hyperaldosteronism	0.669	0.331
M25.0 Haemarthrosis	0.668	0.332
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.667	0.333
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.667	0.333
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.667	0.333
S14 Injury of nerves and spinal cord at neck level	0.667	0.333
T91.8 Sequelae of other specified injuries of neck and trunk	0.666	0.334
H26 Other cataract	0.666	0.334
S91 Open wound of ankle and foot	0.665	0.335
B17.1 Acute hepatitis C	0.665	0.335
M35.9 Systemic involvement of connective tissue, unspecified	0.664	0.336
M35.8 Other specified systemic involvement of connective tissue	0.664	0.336
M35.7 Hypermobility syndrome	0.664	0.336
M35.6 Relapsing panniculitis [Weber-Christian]	0.664	0.336
M35.5 Multifocal fibrosclerosis	0.664	0.336
M35.4 Diffuse (eosinophilic) fasciitis	0.664	0.336
M35.2 Behcet's disease	0.664	0.336
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.664	0.336
Q35-Q37 Cleft lip and cleft palate	0.664	0.336
Q30-Q34 Congenital malformations of the respiratory system	0.664	0.336
Chapter VII Diseases of the eye and adnexa	0.664	0.336
M10 Gout	0.663	0.336
E88 Other metabolic disorders	0.663	0.337
E29 Testicular dysfunction	0.662	0.338
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.661	0.339
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.661	0.339
M14 Arthropathies in other diseases classified elsewhere	0.661	0.339
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.660	0.339
E86 Volume depletion	0.660	0.340
H25-H28 Disorders of lens	0.659	0.341
E21.3 Hyperparathyroidism, unspecified	0.659	0.341
I88 Nonspecific lymphadenitis	0.658	0.342
I82.8 Embolism and thrombosis of other specified veins	0.657	0.343
E64 Sequelae of malnutrition and other nutritional deficiencies	0.657	0.343
E63 Other nutritional deficiencies	0.657	0.343
E56 Other vitamin deficiencies	0.657	0.343
E51 Thiamine deficiency	0.657	0.343
E50 Vitamin A deficiency	0.657	0.343
E60 Dietary zinc deficiency	0.657	0.343
E59 Dietary selenium deficiency	0.657	0.343
E58 Dietary calcium deficiency	0.657	0.343
E54 Ascorbic acid deficiency	0.657	0.343
E52 Niacin deficiency [pellagra]	0.657	0.343
M23.57 Chronic instability of knee (Capsular ligament)	0.657	0.343
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.657	0.343
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.657	0.343
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.657	0.343
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.657	0.343
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.657	0.343
M23.50 Chronic instability of knee (Multiple sites)	0.657	0.343
M54.49 Lumbago with sciatica (Site unspecified)	0.654	0.346
T92.8 Sequelae of other specified injuries of upper limb	0.653	0.347
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.653	0.347
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.653	0.347
T92.4 Sequelae of injury of nerve of upper limb	0.653	0.347
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.653	0.347
Y46 Antiepileptics and anti-Parkinsonism drugs	0.651	0.348
M86 Osteomyelitis	0.651	0.349
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.651	0.349
M54.37 Sciatica (Lumbosacral region)	0.651	0.349
T80 Complications following infusion, transfusion and therapeutic injection	0.650	0.349
V40-V49 Car occupant injured in transport accident	0.650	0.350
I81 Portal vein thrombosis	0.650	0.350
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.650	0.350
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.650	0.350
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.650	0.350
T82.4 Mechanical complication of vascular dialysis catheter	0.650	0.350
V80-V89 Other land transport accidents	0.649	0.350
E78.9 Disorder of lipoprotein metabolism, unspecified	0.649	0.351
X50-X57 Overexertion, travel and privation	0.648	0.351
B65-B83 Helminthiases	0.648	0.352
M41.94 Scoliosis, unspecified (Thoracic region)	0.648	0.352
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.646	0.354
T84.3 Mechanical complication of other bone devices, implants and grafts	0.645	0.355
M90 Osteopathies in diseases classified elsewhere	0.644	0.355
T31.0 Burns involving less than 10% of body surface	0.644	0.356
M11 Other crystal arthropathies	0.644	0.356
I60-I69 Cerebrovascular diseases	0.644	0.356
I00-I02 Acute rheumatic fever	0.643	0.357
M42 Spinal osteochondrosis	0.642	0.357
M40 Kyphosis and lordosis	0.642	0.357
M54.28 Cervicalgia-Sacral/sacrococ	0.642	0.357
M54.27 Cervicalgia-Lumbosacral	0.642	0.357
M54.26 Cervicalgia-Lumbar	0.642	0.357
M54.25 Cervicalgia-Thoracolumbar	0.642	0.357
M54.24 Cervicalgia-Thoracic	0.642	0.357
M54.23 Cervicalgia (Cervicothoracic region)	0.642	0.357
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.642	0.357
M54.20 Cervicalgia-Mult site	0.642	0.357
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.642	0.358
T91.4 Sequelae of injury of intrathoracic organs	0.642	0.358
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.642	0.358
M22.1 Recurrent subluxation of patella	0.642	0.358
M22.9 Disorder of patella, unspecified	0.642	0.358
M22.0 Recurrent dislocation of patella	0.642	0.358
T82.0 Mechanical complication of heart valve prosthesis	0.642	0.358
M47 Spondylosis	0.642	0.358
B18.9 Chronic viral hepatitis, unspecified	0.641	0.358
B18.8 Other chronic viral hepatitis	0.641	0.358
B18.0 Chronic viral hepatitis B with delta-agent	0.641	0.358
A30-A49 Other bacterial diseases	0.641	0.359
M54.56 Low back pain (Lumbar region)	0.641	0.359
M84.1 Nonunion of fracture [pseudarthrosis]	0.640	0.360
Q76 Congenital malformations of spine and bony thorax	0.640	0.360
T16 Foreign body in ear	0.640	0.360
Y85 Sequelae of transport accidents	0.640	0.360
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.638	0.362
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.638	0.362
T85.4 Mechanical complication of breast prosthesis and implant	0.638	0.362
H26.4 After-cataract	0.637	0.363
E66 Obesity	0.635	0.365
E55 Vitamin D deficiency	0.633	0.366
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.633	0.367
I67 Other cerebrovascular diseases	0.632	0.368
I67.8 Other specified cerebrovascular diseases	0.631	0.369
M67.4 Ganglion	0.630	0.369
Chapter VI Diseases of the nervous system	0.631	0.369
I86.8 Varicose veins of other specified sites	0.630	0.370
T87.5 Necrosis of amputation stump	0.629	0.371
T87.3 Neuroma of amputation stump	0.629	0.371
T87.2 Complications of other reattached body part	0.629	0.371
T87.1 Complications of reattached (part of) lower extremity	0.629	0.371
T87.0 Complications of reattached (part of) upper extremity	0.629	0.371
E20 Hypoparathyroidism	0.629	0.371
M34.9 Systemic sclerosis, unspecified	0.629	0.371
T14.1 Open wound of unspecified body region	0.628	0.372
W55 Bitten or struck by other mammals	0.628	0.372
T13 Other injuries of lower limb, level unspecified	0.627	0.373
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.627	0.373
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.627	0.373
I87 Other disorders of veins	0.627	0.373
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.625	0.375
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.624	0.375
M54.47 Lumbago with sciatica (Lumbosacral region)	0.624	0.376
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.624	0.376
E35 Disorders of endocrine glands in diseases classified elsewhere	0.623	0.377
E32 Diseases of thymus	0.623	0.377
E31 Polyglandular dysfunction	0.623	0.377
E30 Disorders of puberty, not elsewhere classified	0.623	0.377
E25 Adrenogenital disorders	0.623	0.377
S99 Other and unspecified injuries of ankle and foot	0.623	0.377
S98 Traumatic amputation of ankle and foot	0.623	0.377
S97 Crushing injury of ankle and foot	0.623	0.377
S96 Injury of muscle and tendon at ankle and foot level	0.623	0.377
S95 Injury of blood vessels at ankle and foot level	0.623	0.377
S94 Injury of nerves at ankle and foot level	0.623	0.377
S12 Fracture of neck	0.622	0.378
Q66 Congenital deformities of feet	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations