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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs571312
log Bayes Factor = 10.5456
Chromosome 18   position 57,839,769  (GRCh37) Explore rs571312 on Ensembl!
Variant rs571312 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E66.9 Obesity, unspecified
1.000 0.000 0.000
E66 Obesity
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
E65-E68 Obesity and other hyperalimentation
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E66.8 Other obesity
0.998 0.002 0.000
E11.9 Without complications
0.996 0.004 0.000
E00-E07 Disorders of thyroid gland
0.996 0.004 0.000
E03 Other hypothyroidism
0.994 0.006 0.000
E03.9 Hypothyroidism, unspecified
0.990 0.010 0.000
E11.4 With neurological complications
0.920 0.080 0.000
E03.8 Other specified hypothyroidism
0.901 0.099 0.000
E11.0 With coma
0.884 0.116 0.000
E11.2 With renal complications
0.872 0.128 0.000
E03.1 Congenital hypothyroidism without goitre
0.849 0.151 0.000
E06 Thyroiditis
0.840 0.160 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.821 0.179 0.000
E10 Insulin-dependent diabetes mellitus
0.799 0.201 0.000
E13 Other specified diabetes mellitus
0.782 0.218 0.000
E11.1 With ketoacidosis
0.778 0.222 0.000
E14 Unspecified diabetes mellitus
0.774 0.226 0.000
E11.8 With unspecified complications
0.773 0.227 0.000
E11.6 With other specified complications
0.759 0.241 0.000
E06.3 Autoimmune thyroiditis
0.753 0.247 0.000
E66.0 Obesity due to excess calories
0.735 0.264 0.000
E04 Other non-toxic goitre
0.725 0.275 0.000
E66.1 Drug-induced obesity
0.717 0.283 0.000
E10.2 With renal complications
0.717 0.283 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E67 Other hyperalimentation
0.716 0.284 0.000
E68 Sequelae of hyperalimentation
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.714 0.286 0.000
E00 Congenital iodine-deficiency syndrome
0.714 0.286 0.000
E03.5 Myxoedema coma
0.713 0.287 0.000
E03.4 Atrophy of thyroid (acquired)
0.713 0.287 0.000
E03.3 Postinfectious hypothyroidism
0.713 0.287 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.713 0.287 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.698 0.302 0.000
E11.5 With peripheral circulatory complications
0.687 0.313 0.000
E04.1 Non-toxic single thyroid nodule
0.686 0.314 0.000
E10.7 With multiple complications
0.667 0.333 0.000
E10.9 Without complications
0.662 0.338 0.000
E06.5 Other chronic thyroiditis
0.661 0.339 0.000
E14.9 Without complications
0.659 0.341 0.000
E11.3 With ophthalmic complications
0.658 0.342 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.644 0.356 0.000
E40-E46 Malnutrition
0.610 0.390 0.000
E14.6 With other specified complications
0.610 0.390 0.000
E13.3 With ophthalmic complications
0.605 0.395 0.000
E07 Other disorders of thyroid
0.604 0.396 0.000
E65 Localised adiposity
0.603 0.397 0.000
E06.4 Drug-induced thyroiditis
0.602 0.398 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.602 0.398 0.000
E06.1 Subacute thyroiditis
0.602 0.398 0.000
E06.0 Acute thyroiditis
0.602 0.398 0.000
E10.5 With peripheral circulatory complications
0.599 0.401 0.000
E10.0 With coma
0.589 0.411 0.000
E14.1 With ketoacidosis
0.589 0.411 0.000
E13.9 Without complications
0.588 0.412 0.000
E10.6 With other specified complications
0.575 0.425 0.000
E04.0 Non-toxic diffuse goitre
0.568 0.432 0.000
E13.8 With unspecified complications
0.561 0.439 0.000
E13.7 With multiple complications
0.561 0.439 0.000
E13.6 With other specified complications
0.561 0.439 0.000
E13.5 With peripheral circulatory complications
0.561 0.439 0.000
E13.4 With neurological complications
0.561 0.439 0.000
E13.2 With renal complications
0.561 0.439 0.000
E13.1 With ketoacidosis
0.561 0.439 0.000
E13.0 With coma
0.561 0.439 0.000
E14.2 Withrenal complications
0.558 0.442 0.000
E14.7 With multiple complications
0.555 0.445 0.000
E14.5 With peripheral circulatory complications
0.555 0.445 0.000
E14.0 With coma
0.555 0.445 0.000
E10.4 With neurological complications
0.553 0.447 0.000
E04.8 Other specified non-toxic goitre
0.520 0.480 0.000
E67.8 Other specified hyperalimentation
0.513 0.486 0.000
E67.3 Hypervitaminosis D
0.513 0.486 0.000
E67.2 Megavitamin-B6 syndrome
0.513 0.486 0.000
E67.1 Hypercarotenaemia
0.513 0.486 0.000
E67.0 Hypervitaminosis A
0.513 0.486 0.000
E12.9 Without complications
0.513 0.486 0.000
E12.8 With unspecified complications
0.513 0.486 0.000
E12.7 With multiple complications
0.513 0.486 0.000
E12.6 With other specified complications
0.513 0.486 0.000
E12.5 With peripheral circulatory complications
0.513 0.486 0.000
E12.4 With neurological complications
0.513 0.486 0.000
E12.3 With ophthalmic complications
0.513 0.486 0.000
E12.2 With renal complications
0.513 0.486 0.000
E12.1 With ketoacidosis
0.513 0.486 0.000
E12.0 With coma
0.513 0.486 0.000
E14.3 With ophthalmic complications
0.513 0.487 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.512 0.488 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.512 0.488 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.512 0.488 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.512 0.488 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.512 0.488 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.512 0.488 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.512 0.488 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.512 0.488 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.510 0.490 0.000
E14.8 With unspecified complications
0.509 0.490 0.000
E10.3 With ophthalmic complications
0.490 0.510 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.462 0.537 0.000
E07.9 Disorder of thyroid, unspecified
0.442 0.558 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.437 0.563 0.000
E45 Retarded development following protein-energy malnutrition
0.437 0.563 0.000
E43 Unspecified severe protein-energy malnutrition
0.437 0.563 0.000
E42 Marasmic kwashiorkor
0.437 0.563 0.000
E41 Nutritional marasmus
0.437 0.563 0.000
E40 Kwashiorkor
0.437 0.563 0.000
E07.1 Dyshormogenetic goitre
0.433 0.567 0.000
E07.0 Hypersecretion of calcitonin
0.433 0.567 0.000
E06.9 Thyroiditis, unspecified
0.433 0.567 0.000
E14.4 With neurological complications
0.429 0.571 0.000
E10.8 With unspecified complications
0.386 0.613 0.001
E50-E64 Other nutritional deficiencies
0.384 0.616 0.000
E15 Nondiabetic hypoglycaemic coma
0.366 0.634 0.000
E05.5 Thyroid crisis or storm
0.332 0.668 0.000
E05.4 Thyrotoxicosis factitia
0.332 0.668 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.332 0.668 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.332 0.668 0.000
E46 Unspecified protein-energy malnutrition
0.331 0.669 0.000
E05.8 Other thyrotoxicosis
0.325 0.675 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.316 0.684 0.000
E44.1 Mild protein-energy malnutrition
0.314 0.686 0.000
E44.0 Moderate protein-energy malnutrition
0.314 0.686 0.000
E07.8 Other specified disorders of thyroid
0.307 0.692 0.000
E10.1 With ketoacidosis
0.305 0.695 0.000
E58 Dietary calcium deficiency
0.302 0.698 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.297 0.703 0.000
E51 Thiamine deficiency
0.276 0.724 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.275 0.724 0.000
E63 Other nutritional deficiencies
0.275 0.724 0.000
E56 Other vitamin deficiencies
0.275 0.724 0.000
E50 Vitamin A deficiency
0.275 0.724 0.000
E60 Dietary zinc deficiency
0.275 0.724 0.000
E59 Dietary selenium deficiency
0.275 0.724 0.000
E54 Ascorbic acid deficiency
0.275 0.724 0.000
E52 Niacin deficiency [pellagra]
0.275 0.724 0.000
E04.9 Non-toxic goitre, unspecified
0.249 0.750 0.000
E55 Vitamin D deficiency
0.217 0.783 0.000
E05.9 Thyrotoxicosis, unspecified
0.206 0.794 0.000
E61 Deficiency of other nutrient elements
0.203 0.797 0.000
E51.2 Wernicke's encephalopathy
0.199 0.801 0.000
E51.9 Thiamine deficiency, unspecified
0.198 0.802 0.000
E51.8 Other manifestations of thiamine deficiency
0.198 0.802 0.000
E51.1 Beriberi
0.198 0.802 0.000
E50.9 Vitamin A deficiency, unspecified
0.198 0.802 0.000
E50.8 Other manifestations of vitamin A deficiency
0.198 0.802 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.198 0.802 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.198 0.802 0.000
E50.5 Vitamin A deficiency with night blindness
0.198 0.802 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.198 0.802 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.198 0.802 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.198 0.802 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.198 0.802 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.198 0.802 0.000
E56.9 Vitamin deficiency, unspecified
0.198 0.802 0.000
E56.8 Deficiency of other vitamins
0.198 0.802 0.000
E56.1 Deficiency of vitamin K
0.198 0.802 0.000
E56.0 Deficiency of vitamin E
0.198 0.802 0.000
E63.9 Nutritional deficiency, unspecified
0.198 0.802 0.000
E63.8 Other specified nutritional deficiencies
0.198 0.802 0.000
E63.1 Imbalance of constituents of food intake
0.198 0.802 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.198 0.802 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.198 0.802 0.000
E64.8 Sequelae of other nutritional deficiencies
0.198 0.802 0.000
E64.3 Sequelae of rickets
0.198 0.802 0.000
E64.2 Sequelae of vitamin C deficiency
0.198 0.802 0.000
E64.1 Sequelae of vitamin A deficiency
0.198 0.802 0.000
E64.0 Sequelae of protein-energy malnutrition
0.198 0.802 0.000
E20-E35 Disorders of other endocrine glands
0.179 0.821 0.000
E16 Other disorders of pancreatic internal secretion
0.160 0.840 0.001
E04.2 Non-toxic multinodular goitre
0.157 0.842 0.000
E55.0 Rickets, active
0.156 0.844 0.000
E53 Deficiency of other B group vitamins
0.155 0.845 0.000
E28 Ovarian dysfunction
0.153 0.847 0.000
E61.9 Deficiency of nutrient element, unspecified
0.146 0.854 0.000
E61.8 Deficiency of other specified nutrient elements
0.146 0.854 0.000
E61.7 Deficiency of multiple nutrient elements
0.146 0.854 0.000
E61.6 Vanadium deficiency
0.146 0.854 0.000
E61.5 Molybdenum deficiency
0.146 0.854 0.000
E61.4 Chromium deficiency
0.146 0.854 0.000
E61.3 Manganese deficiency
0.146 0.854 0.000
E61.0 Copper deficiency
0.146 0.854 0.000
E61.2 Magnesium deficiency
0.140 0.859 0.000
E34 Other endocrine disorders
0.133 0.867 0.000
E28.2 Polycystic ovarian syndrome
0.133 0.867 0.000
E20 Hypoparathyroidism
0.130 0.870 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.128 0.871 0.000
E32 Diseases of thymus
0.128 0.871 0.000
E31 Polyglandular dysfunction
0.128 0.871 0.000
E30 Disorders of puberty, not elsewhere classified
0.128 0.871 0.000
E25 Adrenogenital disorders
0.126 0.874 0.000
E23 Hypofunction and other disorders of pituitary gland
0.120 0.880 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.117 0.883 0.000
E26 Hyperaldosteronism
0.115 0.885 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.114 0.885 0.001
E16.8 Other specified disorders of pancreatic internal secretion
0.114 0.885 0.001
E16.4 Abnormal secretion of gastrin
0.114 0.885 0.001
E16.3 Increased secretion of glucagon
0.114 0.885 0.001
E28.3 Primary ovarian failure
0.112 0.888 0.000
E53.1 Pyridoxine deficiency
0.111 0.888 0.000
E53.0 Riboflavin deficiency
0.111 0.888 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.110 0.890 0.001
E28.9 Ovarian dysfunction, unspecified
0.110 0.890 0.000
E28.8 Other ovarian dysfunction
0.110 0.890 0.000
E28.1 Androgen excess
0.110 0.890 0.000
E28.0 Oestrogen excess
0.110 0.890 0.000
J95.8 Other postprocedural respiratory disorders
0.109 0.891 0.000
E34.0 Carcinoid syndrome
0.107 0.893 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.105 0.895 0.000
E23.2 Diabetes insipidus
0.103 0.897 0.000
E29 Testicular dysfunction
0.102 0.898 0.000
E24 Cushing's syndrome
0.099 0.901 0.000
E34.8 Other specified endocrine disorders
0.098 0.902 0.000
E55.9 Vitamin D deficiency, unspecified
0.098 0.902 0.000
E34.5 Androgen resistance syndrome
0.096 0.904 0.000
E34.4 Constitutional tall stature
0.096 0.904 0.000
E34.3 Short stature, not elsewhere classified
0.096 0.904 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.096 0.904 0.000
E34.1 Other hypersecretion of intestinal hormones
0.096 0.904 0.000
E20.9 Hypoparathyroidism, unspecified
0.094 0.906 0.000
E20.8 Other hypoparathyroidism
0.093 0.907 0.000
E20.1 Pseudohypoparathyroidism
0.093 0.907 0.000
E20.0 Idiopathic hypoparathyroidism
0.093 0.907 0.000
E30.9 Disorder of puberty, unspecified
0.092 0.908 0.000
E30.8 Other disorders of puberty
0.092 0.908 0.000
E30.1 Precocious puberty
0.092 0.908 0.000
E30.0 Delayed puberty
0.092 0.908 0.000
E31.9 Polyglandular dysfunction, unspecified
0.092 0.908 0.000
E31.8 Other polyglandular dysfunction
0.092 0.908 0.000
E31.1 Polyglandular hyperfunction
0.092 0.908 0.000
E31.0 Autoimmune polyglandular failure
0.092 0.908 0.000
E32.9 Disease of thymus, unspecified
0.092 0.908 0.000
E32.8 Other diseases of thymus
0.092 0.908 0.000
E32.1 Abscess of thymus
0.092 0.908 0.000
E32.0 Persistent hyperplasia of thymus
0.092 0.908 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.092 0.908 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.092 0.908 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.092 0.908 0.000
E16.1 Other hypoglycaemia
0.091 0.909 0.001
E25.9 Adrenogenital disorder, unspecified
0.091 0.909 0.000
E25.8 Other adrenogenital disorders
0.091 0.909 0.000
E53.9 Vitamin B deficiency, unspecified
0.090 0.910 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.088 0.911 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.087 0.913 0.000
E23.0 Hypopituitarism
0.087 0.913 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.086 0.913 0.000
E23.1 Drug-induced hypopituitarism
0.086 0.913 0.000
E61.1 Iron deficiency
0.085 0.915 0.000
E21.4 Other specified disorders of parathyroid gland
0.084 0.916 0.000
E21.2 Other hyperparathyroidism
0.084 0.916 0.000
E34.9 Endocrine disorder, unspecified
0.084 0.916 0.000
E26.9 Hyperaldosteronism, unspecified
0.083 0.917 0.000
E26.8 Other hyperaldosteronism
0.083 0.917 0.000
E26.1 Secondary hyperaldosteronism
0.083 0.917 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.082 0.918 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.076 0.924 0.000
I80 Phlebitis and thrombophlebitis
0.076 0.924 0.000
E29.9 Testicular dysfunction, unspecified
0.073 0.926 0.000
E29.8 Other testicular dysfunction
0.073 0.926 0.000
E29.0 Testicular hyperfunction
0.073 0.926 0.000
E24.8 Other Cushing's syndrome
0.071 0.929 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.071 0.929 0.000
E24.3 Ectopic ACTH syndrome
0.071 0.929 0.000
E24.1 Nelson's syndrome
0.071 0.929 0.000
E27 Other disorders of adrenal gland
0.071 0.929 0.000
E26.0 Primary hyperaldosteronism
0.069 0.930 0.000
E23.6 Other disorders of pituitary gland
0.069 0.931 0.000
E23.7 Disorder of pituitary gland, unspecified
0.067 0.933 0.000
E24.0 Pituitary-dependent Cushing's disease
0.067 0.933 0.000
E24.9 Cushing's syndrome, unspecified
0.063 0.937 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.063 0.937 0.000
E21.0 Primary hyperparathyroidism
0.062 0.938 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.062 0.938 0.000
E24.2 Drug-induced Cushing's syndrome
0.061 0.939 0.000
E27.2 Addisonian crisis
0.059 0.941 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.055 0.945 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.053 0.947 0.000
E27.5 Adrenomedullary hyperfunction
0.051 0.949 0.000
E27.0 Other adrenocortical overactivity
0.051 0.949 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.049 0.951 0.000
E27.8 Other specified disorders of adrenal gland
0.048 0.952 0.000
E29.1 Testicular hypofunction
0.047 0.953 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.047 0.953 0.000
E53.8 Deficiency of other specified B group vitamins
0.045 0.955 0.000
E22 Hyperfunction of pituitary gland
0.044 0.956 0.001
E21.3 Hyperparathyroidism, unspecified
0.042 0.958 0.000
E27.1 Primary adrenocortical insufficiency
0.040 0.960 0.000
J95.5 Postprocedural subglottic stenosis
0.039 0.961 0.000
J95.4 Mendelson's syndrome
0.039 0.961 0.000
J95.3 Chronic pulmonary insufficiency following surgery
0.039 0.961 0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.039 0.961 0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.039 0.961 0.000
Z96.6 Presence of orthopaedic joint implants
0.039 0.961 0.000
J95.9 Postprocedural respiratory disorder, unspecified
0.038 0.962 0.000
E27.9 Disorder of adrenal gland, unspecified
0.035 0.965 0.000
J95-J99 Other diseases of the respiratory system
0.033 0.967 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.031 0.968 0.001
E22.8 Other hyperfunction of pituitary gland
0.031 0.968 0.001
M50.1 Cervical disk disorder with radiculopathy
0.000 0.968 0.032
M50 Cervical disk disorders
0.000 0.971 0.029
J95.0 Tracheostomy malfunction
0.029 0.971 0.000
M50.3 Other cervical disk degeneration
0.000 0.971 0.029
J98.0 Diseases of bronchus, not elsewhere classified
0.028 0.972 0.000
J98 Other respiratory disorders
0.028 0.972 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.027 0.973 0.000
M50.2 Other cervical disk displacement
0.000 0.973 0.027
J99 Respiratory disorders in diseases classified elsewhere
0.025 0.975 0.000
J98.9 Respiratory disorder, unspecified
0.025 0.975 0.000
J96 Respiratory failure, not elsewhere classified
0.024 0.976 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.023 0.977 0.000
M20.5 Other deformities of toe(s) (acquired)
0.023 0.977 0.000
M50.8 Other cervical disk disorders
0.000 0.978 0.022
J98.1 Pulmonary collapse
0.022 0.978 0.000
E22.0 Acromegaly and pituitary gigantism
0.021 0.979 0.001
M50.9 Cervical disk disorder, unspecified
0.000 0.979 0.021
C71.2 Temporal lobe
0.021 0.979 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.020 0.980 0.001
J98.3 Compensatory emphysema
0.020 0.980 0.000
C71 Malignant neoplasm of brain
0.020 0.980 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.019 0.981 0.000
E22.1 Hyperprolactinaemia
0.017 0.982 0.001
J98.2 Interstitial emphysema
0.017 0.983 0.000
J96.9 Respiratory failure, unspecified
0.017 0.983 0.000
J96.1 Chronic respiratory failure
0.017 0.983 0.000
J96.0 Acute respiratory failure
0.017 0.983 0.000
C71.3 Parietal lobe
0.017 0.983 0.000
C71.9 Brain, unspecified
0.017 0.983 0.000
T40.2 Other opioids
0.000 0.983 0.017
C67.5 Bladder neck
0.000 0.983 0.017
M50.0 Cervical disk disorder with myelopathy
0.000 0.984 0.016
C71.8 Overlapping lesion of brain
0.016 0.984 0.000
L40.9 Psoriasis, unspecified
0.016 0.984 0.000
C67 Malignant neoplasm of bladder
0.000 0.984 0.016
J98.4 Other disorders of lung
0.015 0.984 0.000
C71.1 Frontal lobe
0.015 0.985 0.000
J98.6 Disorders of diaphragm
0.015 0.985 0.000
M16.0 Primary coxarthrosis, bilateral
0.015 0.985 0.000
C71.0 Cerebrum, except lobes and ventricles
0.015 0.985 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.015 0.985 0.000
M16.9 Coxarthrosis, unspecified
0.015 0.985 0.000
C71.7 Brain stem
0.014 0.986 0.000
C71.6 Cerebellum
0.014 0.986 0.000
C71.5 Cerebral ventricle
0.014 0.986 0.000
H02.8 Other specified disorders of eyelid
0.000 0.986 0.014
C67.6 Ureteric orifice
0.000 0.986 0.014
C67.0 Trigone of bladder
0.000 0.986 0.014
J99.0 Rheumatoid lung disease
0.013 0.986 0.000
M16 Coxarthrosis [arthrosis of hip]
0.014 0.986 0.000
C67.4 Posterior wall of bladder
0.000 0.987 0.013
J32.9 Chronic sinusitis, unspecified
0.000 0.987 0.013
M16.3 Other dysplastic coxarthrosis
0.013 0.987 0.000
C71.4 Occipital lobe
0.013 0.987 0.000
C66 Malignant neoplasm of ureter
0.000 0.987 0.013
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.013 0.987 0.000
J96.09 Acute respiratory failure; Type unspecified
0.012 0.987 0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.012 0.987 0.000
J96.00 Acute respiratory failure; Type I [hypoxic]
0.012 0.987 0.000
J96.19 Chronic respiratory failure; Type unspecified
0.012 0.987 0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.012 0.987 0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.012 0.987 0.000
J96.99 Respiratory failure, unspecified; Type unspecified
0.012 0.987 0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.012 0.987 0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.012 0.987 0.000
C64-C68 Malignant neoplasms of urinary tract
0.000 0.987 0.013
C65 Malignant neoplasm of renal pelvis
0.000 0.988 0.012
C67.2 Lateral wall of bladder
0.000 0.988 0.012
K61.0 Anal abscess
0.012 0.988 0.000
C69 Malignant neoplasm of eye and adnexa
0.012 0.988 0.000
C67.8 Overlapping lesion of bladder
0.000 0.988 0.011
C67.7 Urachus
0.000 0.989 0.011
E16.2 Hypoglycaemia, unspecified
0.010 0.989 0.001
C67.1 Dome of bladder
0.000 0.989 0.011
M16.7 Other secondary coxarthrosis
0.011 0.989 0.000
E70-E90 Metabolic disorders
0.011 0.989 0.000
C69.3 Choroid
0.011 0.989 0.000
C67.3 Anterior wall of bladder
0.000 0.989 0.011
C70 Malignant neoplasm of meninges
0.010 0.990 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.010 0.990 0.000
I10 Essential (primary) hypertension
0.010 0.990 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.010 0.990 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.010 0.990 0.000
H35.8 Other specified retinal disorders
0.010 0.990 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.009 0.990 0.000
G56.0 Carpal tunnel syndrome
0.009 0.991 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.991 0.009
J98.8 Other specified respiratory disorders
0.009 0.991 0.000
N13.8 Other obstructive and reflux uropathy
0.009 0.991 0.000
E73 Lactose intolerance
0.009 0.991 0.000
E72 Other disorders of amino-acid metabolism
0.009 0.991 0.000
L40 Psoriasis
0.009 0.991 0.000
C69.8 Overlapping lesion of eye and adnexa
0.008 0.991 0.000
C69.6 Orbit
0.008 0.991 0.000
C69.5 Lachrymal gland and duct
0.008 0.991 0.000
C69.4 Ciliary body
0.008 0.991 0.000
C69.2 Retina
0.008 0.991 0.000
C69.1 Cornea
0.008 0.991 0.000
C69.0 Conjunctiva
0.008 0.992 0.000
C70.0 Cerebral meninges
0.008 0.992 0.000
E84 Cystic fibrosis
0.008 0.992 0.000
E77 Disorders of glycoprotein metabolism
0.008 0.992 0.000
E76 Disorders of glycosaminoglycan metabolism
0.008 0.992 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.008 0.992 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.008 0.992 0.000
E70 Disorders of aromatic amino-acid metabolism
0.008 0.992 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.008 0.992 0.000
E88 Other metabolic disorders
0.008 0.992 0.000
C69.9 Eye, unspecified
0.008 0.992 0.000
E79 Disorders of purine and pyrimidine metabolism
0.008 0.992 0.000
E83 Disorders of mineral metabolism
0.008 0.992 0.000
E83.3 Disorders of phosphorus metabolism
0.008 0.992 0.000
N63 Unspecified lump in breast
0.000 0.992 0.008
L40.0 Psoriasis vulgaris
0.008 0.992 0.000
M16.5 Other posttraumatic coxarthrosis
0.008 0.992 0.000
C70.9 Meninges, unspecified
0.007 0.992 0.000
C70.1 Spinal meninges
0.007 0.992 0.000
K50.0 Crohn's disease of small intestine
0.007 0.993 0.000
E73.9 Lactose intolerance, unspecified
0.007 0.993 0.000
L40.1 Generalised pustular psoriasis
0.007 0.993 0.000
C72.9 Central nervous system, unspecified
0.007 0.993 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.007 0.993 0.000
C72.5 Other and unspecified cranial nerves
0.007 0.993 0.000
C72.4 Acoustic nerve
0.007 0.993 0.000
C72.3 Optic nerve
0.007 0.993 0.000
C72.2 Olfactory nerve
0.007 0.993 0.000
C72.1 Cauda equina
0.007 0.993 0.000
C72.0 Spinal cord
0.007 0.993 0.000
C68.9 Urinary organ, unspecified
0.000 0.993 0.007
C68.8 Overlapping lesion of urinary organs
0.000 0.993 0.007
C68.1 Paraurethral glands
0.000 0.993 0.007
E74 Other disorders of carbohydrate metabolism
0.007 0.993 0.000
C68.0 Urethra
0.000 0.993 0.007
E72.0 Disorders of amino-acid transport
0.007 0.993 0.000
E73.8 Other lactose intolerance
0.007 0.993 0.000
E73.1 Secondary lactase deficiency
0.007 0.993 0.000
E73.0 Congenital lactase deficiency
0.007 0.993 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.007 0.993 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.007 0.993 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.001 0.993 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.006 0.994 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.006 0.994 0.000
E72.5 Disorders of glycine metabolism
0.006 0.994 0.000
E72.4 Disorders of ornithine metabolism
0.006 0.994 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.006 0.994 0.000
E72.2 Disorders of urea cycle metabolism
0.006 0.994 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.006 0.994 0.000
L40.4 Guttate psoriasis
0.006 0.994 0.000
L40.3 Pustulosis palmaris et plantaris
0.006 0.994 0.000
L40.2 Acrodermatitis continua
0.006 0.994 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.006 0.994 0.000
K50.8 Other Crohn's disease
0.006 0.994 0.000
E88.9 Metabolic disorder, unspecified
0.006 0.994 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.994 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.994 0.000
E70.3 Albinism
0.006 0.994 0.000
E70.2 Disorders of tyrosine metabolism
0.006 0.994 0.000
E70.1 Other hyperphenylalaninaemias
0.006 0.994 0.000
E70.0 Classical phenylketonuria
0.006 0.994 0.000
E71.3 Disorders of fatty-acid metabolism
0.006 0.994 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.006 0.994 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.006 0.994 0.000
E71.0 Maple-syrup-urine disease
0.006 0.994 0.000
E75.6 Lipid storage disorder, unspecified
0.006 0.994 0.000
E75.5 Other lipid storage disorders
0.006 0.994 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.006 0.994 0.000
E75.3 Sphingolipidosis, unspecified
0.006 0.994 0.000
E75.2 Other sphingolipidosis
0.006 0.994 0.000
E75.1 Other gangliosidosis
0.006 0.994 0.000
E75.0 GM2 gangliosidosis
0.006 0.994 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.006 0.994 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.006 0.994 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.006 0.994 0.000
E76.2 Other mucopolysaccharidoses
0.006 0.994 0.000
E76.1 Mucopolysaccharidosis, type II
0.006 0.994 0.000
E76.0 Mucopolysaccharidosis, type I
0.006 0.994 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.006 0.994 0.000
E77.8 Other disorders of glycoprotein metabolism
0.006 0.994 0.000
E77.1 Defects in glycoprotein degradation
0.006 0.994 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.006 0.994 0.000
E84.8 Cystic fibrosis with other manifestations
0.006 0.994 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.006 0.994 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.006 0.994 0.000
E84.9 Cystic fibrosis, unspecified
0.006 0.994 0.000
E88.3 Tumour lysis syndrome
0.006 0.994 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.006 0.994 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.006 0.994 0.000
E79.1 Lesch-Nyhan syndrome
0.006 0.994 0.000
E83.8 Other disorders of mineral metabolism
0.006 0.994 0.000
E83.2 Disorders of zinc metabolism
0.006 0.994 0.000
E83.0 Disorders of copper metabolism
0.006 0.994 0.000
K50 Crohn's disease [regional enteritis]
0.006 0.994 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.006 0.994 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.006 0.994 0.000
K50.9 Crohn's disease, unspecified
0.006 0.994 0.000
E88.8 Other specified metabolic disorders
0.006 0.994 0.000
T40.6 Other and unspecified narcotics
0.000 0.994 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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