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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs573179
log Bayes Factor = 100.174
Chromosome 6   position 27,849,676  (GRCh37) Explore rs573179 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.001 0.999
E03 Other hypothyroidism
0.999 0.001 0.000
E03.9 Hypothyroidism, unspecified
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.995 0.005 0.000
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
E10.3 With ophthalmic complications
0.992 0.008 0.000
K40 Inguinal hernia
0.000 0.010 0.990
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.987 0.013 0.000
E20-E35 Disorders of other endocrine glands
0.985 0.015 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.018 0.982
E23 Hypofunction and other disorders of pituitary gland
0.964 0.036 0.000
N40-N51 Diseases of male genital organs
0.000 0.045 0.955
E14.3 With ophthalmic complications
0.951 0.049 0.000
N41 Inflammatory diseases of prostate
0.000 0.050 0.950
E27 Other disorders of adrenal gland
0.932 0.068 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.073 0.927
E10.1 With ketoacidosis
0.926 0.074 0.000
N42 Other disorders of prostate
0.000 0.086 0.914
E27.1 Primary adrenocortical insufficiency
0.913 0.087 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.909 0.091 0.000
E10.6 With other specified complications
0.908 0.092 0.000
E10.2 With renal complications
0.904 0.096 0.000
N41.0 Acute prostatitis
0.000 0.102 0.898
E23.2 Diabetes insipidus
0.889 0.111 0.000
E23.0 Hypopituitarism
0.888 0.112 0.000
N42.8 Other specified disorders of prostate
0.000 0.116 0.884
E14.9 Without complications
0.863 0.137 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.832 0.168 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.828 0.172 0.000
E11 Non-insulin-dependent diabetes mellitus
0.823 0.177 0.000
K90 Intestinal malabsorption
0.819 0.178 0.002
E14.4 With neurological complications
0.820 0.180 0.000
N46 Male infertility
0.000 0.180 0.820
N45 Orchitis and epididymitis
0.000 0.185 0.815
E10.4 With neurological complications
0.814 0.186 0.000
E50-E64 Other nutritional deficiencies
0.809 0.191 0.000
E07 Other disorders of thyroid
0.807 0.193 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.193 0.807
E10.0 With coma
0.805 0.195 0.000
E11.5 With peripheral circulatory complications
0.785 0.215 0.000
E11.3 With ophthalmic complications
0.781 0.219 0.000
N41.1 Chronic prostatitis
0.000 0.223 0.777
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.773 0.227 0.001
E24 Cushing's syndrome
0.773 0.227 0.000
E20 Hypoparathyroidism
0.770 0.230 0.000
E14.2 Withrenal complications
0.762 0.238 0.000
E10.7 With multiple complications
0.757 0.243 0.000
E10.5 With peripheral circulatory complications
0.756 0.243 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.756 0.244 0.000
N44 Torsion of testis
0.000 0.246 0.754
E23.7 Disorder of pituitary gland, unspecified
0.752 0.248 0.000
E31 Polyglandular dysfunction
0.749 0.251 0.000
E14.6 With other specified complications
0.748 0.252 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.252 0.748
N42.0 Calculus of prostate
0.000 0.255 0.745
E16.1 Other hypoglycaemia
0.736 0.264 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.729 0.271 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.717 0.283 0.000
E03.5 Myxoedema coma
0.716 0.284 0.000
E03.4 Atrophy of thyroid (acquired)
0.716 0.284 0.000
E03.3 Postinfectious hypothyroidism
0.716 0.284 0.000
E03.1 Congenital hypothyroidism without goitre
0.716 0.284 0.000
E23.6 Other disorders of pituitary gland
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.290 0.710
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.290 0.710
E14.7 With multiple complications
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.706 0.294 0.000
E32 Diseases of thymus
0.706 0.294 0.000
E30 Disorders of puberty, not elsewhere classified
0.706 0.294 0.000
E29 Testicular dysfunction
0.696 0.304 0.000
E53 Deficiency of other B group vitamins
0.693 0.307 0.000
E14.1 With ketoacidosis
0.692 0.308 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.691 0.309 0.000
E23.1 Drug-induced hypopituitarism
0.691 0.309 0.000
E27.9 Disorder of adrenal gland, unspecified
0.690 0.310 0.000
E27.2 Addisonian crisis
0.690 0.310 0.000
N41.3 Prostatocystitis
0.000 0.319 0.681
N41.2 Abscess of prostate
0.000 0.319 0.681
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.320 0.680
E14.5 With peripheral circulatory complications
0.676 0.324 0.000
E07.8 Other specified disorders of thyroid
0.676 0.324 0.000
E11.0 With coma
0.675 0.325 0.000
E11.6 With other specified complications
0.671 0.329 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.332 0.668
E02 Subclinical iodine-deficiency hypothyroidism
0.668 0.332 0.000
E27.5 Adrenomedullary hyperfunction
0.668 0.332 0.000
E27.0 Other adrenocortical overactivity
0.668 0.332 0.000
N42.3 Dysplasia of prostate
0.000 0.344 0.656
E14.8 With unspecified complications
0.648 0.352 0.000
E24.2 Drug-induced Cushing's syndrome
0.643 0.357 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.631 0.369 0.000
E10.8 With unspecified complications
0.625 0.374 0.000
E53.8 Deficiency of other specified B group vitamins
0.622 0.378 0.000
E06 Thyroiditis
0.621 0.379 0.000
E20.9 Hypoparathyroidism, unspecified
0.616 0.384 0.000
E61 Deficiency of other nutrient elements
0.604 0.396 0.000
K90.9 Intestinal malabsorption, unspecified
0.601 0.398 0.001
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.401 0.599
K90.8 Other intestinal malabsorption
0.594 0.404 0.002
E51 Thiamine deficiency
0.596 0.404 0.000
E21.0 Primary hyperparathyroidism
0.591 0.409 0.000
E11.7 With multiple complications
0.590 0.410 0.000
E58 Dietary calcium deficiency
0.589 0.410 0.000
K90.3 Pancreatic steatorrhoea
0.587 0.411 0.002
K90.2 Blind loop syndrome, not elsewhere classified
0.587 0.411 0.002
K90.1 Tropical sprue
0.587 0.411 0.002
E03.8 Other specified hypothyroidism
0.587 0.412 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.414 0.585
E40-E46 Malnutrition
0.585 0.414 0.000
E24.0 Pituitary-dependent Cushing's disease
0.584 0.416 0.000
N42.2 Atrophy of prostate
0.000 0.418 0.582
E26 Hyperaldosteronism
0.582 0.418 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.580 0.420 0.000
E63 Other nutritional deficiencies
0.580 0.420 0.000
E56 Other vitamin deficiencies
0.580 0.420 0.000
E50 Vitamin A deficiency
0.580 0.420 0.000
E60 Dietary zinc deficiency
0.580 0.420 0.000
E59 Dietary selenium deficiency
0.580 0.420 0.000
E54 Ascorbic acid deficiency
0.580 0.420 0.000
E52 Niacin deficiency [pellagra]
0.580 0.420 0.000
E31.0 Autoimmune polyglandular failure
0.580 0.420 0.000
E07.1 Dyshormogenetic goitre
0.579 0.421 0.000
E07.0 Hypersecretion of calcitonin
0.579 0.421 0.000
E05.8 Other thyrotoxicosis
0.578 0.422 0.000
E21.3 Hyperparathyroidism, unspecified
0.572 0.428 0.000
E07.9 Disorder of thyroid, unspecified
0.566 0.433 0.000
E21.2 Other hyperparathyroidism
0.563 0.437 0.000
E34 Other endocrine disorders
0.558 0.442 0.000
E13.3 With ophthalmic complications
0.555 0.445 0.000
E24.8 Other Cushing's syndrome
0.554 0.446 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.554 0.446 0.000
E24.3 Ectopic ACTH syndrome
0.554 0.446 0.000
E24.1 Nelson's syndrome
0.554 0.446 0.000
E20.8 Other hypoparathyroidism
0.552 0.448 0.000
E20.1 Pseudohypoparathyroidism
0.552 0.448 0.000
E20.0 Idiopathic hypoparathyroidism
0.552 0.448 0.000
E11.1 With ketoacidosis
0.549 0.451 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.542 0.458 0.000
E21.4 Other specified disorders of parathyroid gland
0.542 0.458 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.539 0.461 0.000
E31.9 Polyglandular dysfunction, unspecified
0.537 0.463 0.000
E31.8 Other polyglandular dysfunction
0.537 0.463 0.000
E31.1 Polyglandular hyperfunction
0.537 0.463 0.000
E28 Ovarian dysfunction
0.536 0.464 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.518 0.482 0.000
E13.8 With unspecified complications
0.514 0.486 0.000
E13.7 With multiple complications
0.514 0.486 0.000
E13.6 With other specified complications
0.514 0.486 0.000
E13.5 With peripheral circulatory complications
0.514 0.486 0.000
E13.4 With neurological complications
0.514 0.486 0.000
E13.2 With renal complications
0.514 0.486 0.000
E13.1 With ketoacidosis
0.514 0.486 0.000
E13.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E25.9 Adrenogenital disorder, unspecified
0.511 0.489 0.000
E25.8 Other adrenogenital disorders
0.511 0.489 0.000
E30.9 Disorder of puberty, unspecified
0.506 0.494 0.000
E30.8 Other disorders of puberty
0.506 0.494 0.000
E30.1 Precocious puberty
0.506 0.494 0.000
E30.0 Delayed puberty
0.506 0.494 0.000
E32.9 Disease of thymus, unspecified
0.506 0.494 0.000
E32.8 Other diseases of thymus
0.506 0.494 0.000
E32.1 Abscess of thymus
0.506 0.494 0.000
E32.0 Persistent hyperplasia of thymus
0.506 0.494 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.506 0.494 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.506 0.494 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.506 0.494 0.000
E61.1 Iron deficiency
0.501 0.499 0.000
E29.9 Testicular dysfunction, unspecified
0.499 0.501 0.000
E29.8 Other testicular dysfunction
0.499 0.501 0.000
E29.0 Testicular hyperfunction
0.499 0.501 0.000
E53.1 Pyridoxine deficiency
0.497 0.503 0.000
E53.0 Riboflavin deficiency
0.497 0.503 0.000
E29.1 Testicular hypofunction
0.489 0.511 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.512 0.488
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.512 0.488
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.512 0.488
E06.9 Thyroiditis, unspecified
0.484 0.515 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.516 0.483
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.483 0.517 0.000
E24.9 Cushing's syndrome, unspecified
0.478 0.522 0.000
E55 Vitamin D deficiency
0.475 0.525 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.530 0.470
E13.9 Without complications
0.464 0.536 0.000
E53.9 Vitamin B deficiency, unspecified
0.462 0.538 0.000
E22 Hyperfunction of pituitary gland
0.461 0.539 0.000
E06.5 Other chronic thyroiditis
0.453 0.547 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.551 0.449
E06.4 Drug-induced thyroiditis
0.445 0.554 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.445 0.554 0.000
E06.1 Subacute thyroiditis
0.445 0.554 0.000
E06.0 Acute thyroiditis
0.445 0.554 0.000
E51.2 Wernicke's encephalopathy
0.443 0.557 0.000
E11.8 With unspecified complications
0.439 0.561 0.000
E61.9 Deficiency of nutrient element, unspecified
0.433 0.567 0.000
E61.8 Deficiency of other specified nutrient elements
0.433 0.567 0.000
E61.7 Deficiency of multiple nutrient elements
0.433 0.567 0.000
E61.6 Vanadium deficiency
0.433 0.567 0.000
E61.5 Molybdenum deficiency
0.433 0.567 0.000
E61.4 Chromium deficiency
0.433 0.567 0.000
E61.3 Manganese deficiency
0.433 0.567 0.000
E61.0 Copper deficiency
0.433 0.567 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.570 0.430
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.570 0.430
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.570 0.430
E51.9 Thiamine deficiency, unspecified
0.427 0.573 0.000
E51.8 Other manifestations of thiamine deficiency
0.427 0.573 0.000
E51.1 Beriberi
0.427 0.573 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.420 0.580 0.000
E45 Retarded development following protein-energy malnutrition
0.420 0.580 0.000
E43 Unspecified severe protein-energy malnutrition
0.420 0.580 0.000
E42 Marasmic kwashiorkor
0.420 0.580 0.000
E41 Nutritional marasmus
0.420 0.580 0.000
E40 Kwashiorkor
0.420 0.580 0.000
E26.9 Hyperaldosteronism, unspecified
0.417 0.583 0.000
E26.8 Other hyperaldosteronism
0.417 0.583 0.000
E26.1 Secondary hyperaldosteronism
0.417 0.583 0.000
E50.9 Vitamin A deficiency, unspecified
0.416 0.584 0.000
E50.8 Other manifestations of vitamin A deficiency
0.416 0.584 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.416 0.584 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.416 0.584 0.000
E50.5 Vitamin A deficiency with night blindness
0.416 0.584 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.416 0.584 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.416 0.584 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.416 0.584 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.416 0.584 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.416 0.584 0.000
E56.9 Vitamin deficiency, unspecified
0.416 0.584 0.000
E56.8 Deficiency of other vitamins
0.416 0.584 0.000
E56.1 Deficiency of vitamin K
0.416 0.584 0.000
E56.0 Deficiency of vitamin E
0.416 0.584 0.000
E63.9 Nutritional deficiency, unspecified
0.416 0.584 0.000
E63.8 Other specified nutritional deficiencies
0.416 0.584 0.000
E63.1 Imbalance of constituents of food intake
0.416 0.584 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.416 0.584 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.416 0.584 0.000
E64.8 Sequelae of other nutritional deficiencies
0.416 0.584 0.000
E64.3 Sequelae of rickets
0.416 0.584 0.000
E64.2 Sequelae of vitamin C deficiency
0.416 0.584 0.000
E64.1 Sequelae of vitamin A deficiency
0.416 0.584 0.000
E64.0 Sequelae of protein-energy malnutrition
0.416 0.584 0.000
E34.8 Other specified endocrine disorders
0.406 0.594 0.000
E34.5 Androgen resistance syndrome
0.400 0.600 0.000
E34.4 Constitutional tall stature
0.400 0.600 0.000
E34.3 Short stature, not elsewhere classified
0.400 0.600 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.400 0.600 0.000
E34.1 Other hypersecretion of intestinal hormones
0.400 0.600 0.000
E28.9 Ovarian dysfunction, unspecified
0.385 0.615 0.000
E28.8 Other ovarian dysfunction
0.385 0.615 0.000
E28.1 Androgen excess
0.385 0.615 0.000
E28.0 Oestrogen excess
0.385 0.615 0.000
E28.3 Primary ovarian failure
0.375 0.624 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.625 0.375
E22.1 Hyperprolactinaemia
0.367 0.633 0.000
E61.2 Magnesium deficiency
0.359 0.641 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.643 0.356
E34.0 Carcinoid syndrome
0.348 0.652 0.000
E55.0 Rickets, active
0.340 0.659 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.330 0.669 0.000
E22.8 Other hyperfunction of pituitary gland
0.330 0.669 0.000
E34.9 Endocrine disorder, unspecified
0.318 0.681 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.689 0.311
N43 Hydrocele and spermatocele
0.000 0.693 0.307
E44.1 Mild protein-energy malnutrition
0.301 0.699 0.000
E44.0 Moderate protein-energy malnutrition
0.301 0.699 0.000
E26.0 Primary hyperaldosteronism
0.293 0.707 0.001
E46 Unspecified protein-energy malnutrition
0.288 0.711 0.000
E11.2 With renal complications
0.285 0.715 0.000
E65-E68 Obesity and other hyperalimentation
0.272 0.728 0.000
K40-K46 Hernia
0.000 0.729 0.271
E06.3 Autoimmune thyroiditis
0.257 0.743 0.000
E27.8 Other specified disorders of adrenal gland
0.237 0.760 0.003
K41 Femoral hernia
0.000 0.761 0.239
E55.9 Vitamin D deficiency, unspecified
0.235 0.765 0.000
E28.2 Polycystic ovarian syndrome
0.233 0.767 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.773 0.227
K46 Unspecified abdominal hernia
0.000 0.776 0.224
N43.2 Other hydrocele
0.000 0.779 0.220
N43.1 Infected hydrocele
0.000 0.779 0.220
N43.0 Encysted hydrocele
0.000 0.779 0.220
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.208 0.792 0.000
K44 Diaphragmatic hernia
0.000 0.794 0.206
N42.9 Disorder of prostate, unspecified
0.000 0.797 0.202
N48 Other disorders of penis
0.000 0.799 0.201
K92 Other diseases of digestive system
0.001 0.801 0.198
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.802 0.198
K92.0 Haematemesis
0.000 0.802 0.198
E67 Other hyperalimentation
0.195 0.805 0.000
E68 Sequelae of hyperalimentation
0.195 0.805 0.000
K92.9 Disease of digestive system, unspecified
0.000 0.807 0.193
E22.0 Acromegaly and pituitary gigantism
0.191 0.808 0.001
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.811 0.189
N50 Other disorders of male genital organs
0.000 0.821 0.179
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.828 0.172
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.828 0.172
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.828 0.172
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.828 0.172
N48.2 Other inflammatory disorders of penis
0.000 0.830 0.170
N48.4 Impotence of organic origin
0.000 0.832 0.168
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.836 0.164
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.838 0.161
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.839 0.160
I83 Varicose veins of lower extremities
0.000 0.841 0.159
N48.1 Balanoposthitis
0.000 0.844 0.156
N43.4 Spermatocele
0.001 0.846 0.154
K90-K93 Other diseases of the digestive system
0.062 0.846 0.092
K44.1 Diaphragmatic hernia with gangrene
0.000 0.852 0.148
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.858 0.142
E67.8 Other specified hyperalimentation
0.140 0.860 0.000
E67.3 Hypervitaminosis D
0.140 0.860 0.000
E67.2 Megavitamin-B6 syndrome
0.140 0.860 0.000
E67.1 Hypercarotenaemia
0.140 0.860 0.000
E67.0 Hypervitaminosis A
0.140 0.860 0.000
N48.5 Ulcer of penis
0.000 0.863 0.137
N50.9 Disorder of male genital organs, unspecified
0.000 0.868 0.132
N50.0 Atrophy of testis
0.000 0.880 0.120
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.881 0.119
E11.4 With neurological complications
0.118 0.881 0.001
K92.8 Other specified diseases of digestive system
0.001 0.881 0.118
N48.3 Priapism
0.000 0.883 0.116
K93 Disorders of other digestive organs in diseases classified elsewhere
0.045 0.889 0.066
K45 Other abdominal hernia
0.001 0.891 0.108
E65 Localised adiposity
0.106 0.893 0.001
E83 Disorders of mineral metabolism
0.001 0.894 0.105
K42 Umbilical hernia
0.000 0.899 0.101
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.899 0.101
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.906 0.094
N48.9 Disorder of penis, unspecified
0.000 0.909 0.091
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.910 0.090
N48.0 Leukoplakia of penis
0.000 0.911 0.088
K92.1 Melaena
0.000 0.917 0.083
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.032 0.920 0.048
K93.1 Megacolon in Chagas' disease
0.032 0.920 0.048
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.032 0.920 0.048
E04 Other non-toxic goitre
0.078 0.921 0.000
K45.1 Other specified abdominal hernia with gangrene
0.001 0.922 0.078
K43 Ventral hernia
0.000 0.922 0.078
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.924 0.075
E83.8 Other disorders of mineral metabolism
0.001 0.924 0.075
E83.2 Disorders of zinc metabolism
0.001 0.924 0.075
E83.0 Disorders of copper metabolism
0.001 0.924 0.075
E83.3 Disorders of phosphorus metabolism
0.000 0.924 0.076
E11.9 Without complications
0.075 0.925 0.000
Chapter XI Diseases of the digestive system
0.000 0.927 0.073
K42.1 Umbilical hernia with gangrene
0.000 0.928 0.072
N48.8 Other specified disorders of penis
0.000 0.934 0.066
K50-K52 Noninfective enteritis and colitis
0.000 0.936 0.064
K35-K38 Diseases of appendix
0.000 0.937 0.063
K37 Unspecified appendicitis
0.000 0.938 0.062
A04 Other bacterial intestinal infections
0.000 0.939 0.061
K50 Crohn's disease [regional enteritis]
0.000 0.940 0.060
N48.6 Balanitis xerotica obliterans
0.000 0.940 0.060
R47.0 Dysphasia and aphasia
0.059 0.941 0.000
E04.8 Other specified non-toxic goitre
0.056 0.943 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.943 0.056
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.944 0.056
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.944 0.056
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.944 0.056
K43.4 Parastomal hernia with gangrene
0.000 0.944 0.056
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.944 0.056
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.944 0.056
K43.1 Ventral hernia with gangrene
0.000 0.944 0.056
K50.1 Crohn's disease of large intestine
0.000 0.944 0.056
K51 Ulcerative colitis
0.000 0.946 0.054
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.946 0.054
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.946 0.054
K38 Other diseases of appendix
0.000 0.948 0.052
K50.0 Crohn's disease of small intestine
0.000 0.948 0.052
A04.4 Other intestinal Escherichia coli infections
0.000 0.950 0.050
A04.9 Bacterial intestinal infection, unspecified
0.000 0.952 0.048
K51.2 Ulcerative (chronic) proctitis
0.000 0.953 0.047
K38.8 Other specified diseases of appendix
0.000 0.953 0.047
A04.5 Campylobacter enteritis
0.000 0.953 0.047
K50.8 Other Crohn's disease
0.000 0.954 0.046
K51.4 Pseudopolyposis of colon
0.000 0.954 0.046
K51.9 Ulcerative colitis, unspecified
0.000 0.954 0.046
A04.8 Other specified bacterial intestinal infections
0.000 0.956 0.044
A04.6 Enteritis due to Yersinia enterocolitica
0.000 0.956 0.044
A04.3 Enterohaemorrhagic Escherichia coli infection
0.000 0.956 0.044
A04.2 Enteroinvasive Escherichia coli infection
0.000 0.956 0.044
A04.1 Enterotoxigenic Escherichia coli infection
0.000 0.956 0.044
A04.0 Enteropathogenic Escherichia coli infection
0.000 0.956 0.044
N43.3 Hydrocele, unspecified
0.000 0.956 0.044
E83.4 Disorders of magnesium metabolism
0.001 0.956 0.043
R47 Speech disturbances, not elsewhere classified
0.042 0.958 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.959 0.040
E04.0 Non-toxic diffuse goitre
0.040 0.959 0.001
R47.1 Dysarthria and anarthria
0.040 0.960 0.000
K50.9 Crohn's disease, unspecified
0.000 0.961 0.039
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.962 0.038
K51.5 Mucosal proctocolitis
0.000 0.962 0.038
K38.3 Fistula of appendix
0.000 0.962 0.037
K38.2 Diverticulum of appendix
0.000 0.962 0.037
K38.0 Hyperplasia of appendix
0.000 0.962 0.037
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.963 0.037
K36 Other appendicitis
0.000 0.964 0.035
K38.1 Appendicular concretions
0.000 0.964 0.035
E04.9 Non-toxic goitre, unspecified
0.034 0.966 0.000
K38.9 Disease of appendix, unspecified
0.000 0.967 0.033
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.968 0.032
H36.0 Diabetic retinopathy
0.032 0.968 0.000
K65-K67 Diseases of peritoneum
0.000 0.969 0.031
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.012 0.969 0.019
K51.8 Other ulcerative colitis
0.000 0.969 0.031
M20.1 Hallux valgus (acquired)
0.000 0.970 0.030
E66 Obesity
0.029 0.971 0.000
K75.4 Autoimmune hepatitis
0.028 0.972 0.000
N50.1 Vascular disorders of male genital organs
0.000 0.972 0.028
K75.8 Other specified inflammatory liver diseases
0.027 0.973 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.974 0.026
K75 Other inflammatory liver diseases
0.025 0.974 0.001
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.975 0.025
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.975 0.024
I82 Other venous embolism and thrombosis
0.000 0.977 0.023
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.977 0.023
K91.5 Postcholecystectomy syndrome
0.009 0.977 0.014
K91.2 Postsurgical malabsorption, not elsewhere classified
0.007 0.978 0.015
H36 Retinal disorders in diseases classified elsewhere
0.022 0.978 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.978 0.022
E66.1 Drug-induced obesity
0.021 0.979 0.000
K91.1 Postgastric surgery syndromes
0.009 0.979 0.013
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.979 0.021
R47.8 Other and unspecified speech disturbances
0.021 0.979 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.007 0.979 0.013
K75.9 Inflammatory liver disease, unspecified
0.020 0.980 0.000
I88 Nonspecific lymphadenitis
0.000 0.980 0.020
K91.9 Postprocedural disorder of digestive system, unspecified
0.011 0.980 0.010
E04.1 Non-toxic single thyroid nodule
0.020 0.980 0.000
I87 Other disorders of veins
0.000 0.980 0.020
N84.1 Polyp of cervix uteri
0.000 0.980 0.020
I82.3 Embolism and thrombosis of renal vein
0.000 0.981 0.019
K75.3 Granulomatous hepatitis, not elsewhere classified
0.018 0.981 0.001
K75.2 Nonspecific reactive hepatitis
0.018 0.981 0.001
K75.1 Phlebitis of portal vein
0.018 0.981 0.001
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.981 0.019
K66 Other disorders of peritoneum
0.000 0.982 0.018
I80 Phlebitis and thrombophlebitis
0.000 0.982 0.018
I87.1 Compression of vein
0.000 0.982 0.018
E66.2 Extreme obesity with alveolar hypoventilation
0.017 0.982 0.000
K66.9 Disorder of peritoneum, unspecified
0.000 0.983 0.017
I82.2 Embolism and thrombosis of vena cava
0.000 0.983 0.017
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.983 0.017
I82.1 Thrombophlebitis migrans
0.000 0.983 0.017
I82.0 Budd-Chiari syndrome
0.000 0.983 0.017
H34.8 Other retinal vascular occlusions
0.017 0.983 0.000
L72.0 Epidermal cyst
0.000 0.983 0.017
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.983 0.016
K67.3 Tuberculous peritonitis
0.000 0.983 0.016
K67.2 Syphilitic peritonitis
0.000 0.983 0.016
K67.1 Gonococcal peritonitis
0.000 0.983 0.016
K67.0 Chlamydial peritonitis
0.000 0.983 0.016
E66.0 Obesity due to excess calories
0.016 0.984 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.984 0.016
I85 Oesophageal varices
0.000 0.984 0.016
H34 Retinal vascular occlusions
0.016 0.984 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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