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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5754891
log Bayes Factor = <0.0001
Chromosome 22   position 34,602,188  (GRCh37) Explore rs5754891 on Ensembl!
Variant rs5754891 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.000 0.991 0.009
M05.9 Seropositive rheumatoid arthritis, unspecified
0.008 0.992 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.007 0.993 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.007 0.993 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.007 0.993 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.007 0.993 0.000
M25.37 Other instability of joint (Ankle and foot)
0.007 0.993 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.006 0.994 0.000
G82.2 Paraplegia, unspecified
0.000 0.994 0.006
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.006 0.994 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.006 0.994 0.000
K14.0 Glossitis
0.006 0.994 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.006 0.994 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.006 0.994 0.000
E23.0 Hypopituitarism
0.006 0.994 0.000
O20.0 Threatened abortion
0.005 0.995 0.000
M47.2 Other spondylosis with radiculopathy
0.000 0.995 0.005
Z11.5 Special screening examination for other viral diseases
0.000 0.995 0.005
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.000 0.996 0.004
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.000 0.996 0.004
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.004 0.996 0.000
S52.50 Fracture of lower end of radius (closed)
0.004 0.996 0.000
M05 Seropositive rheumatoid arthritis
0.004 0.996 0.000
Y79.2 Prosthetic and other implants, materials and accessory devices
0.000 0.996 0.004
Z11.2 Special screening examination for other bacterial diseases
0.000 0.996 0.004
Z11 Special screening examination for infectious and parasitic diseases
0.000 0.996 0.004
T51.0 Ethanol
0.004 0.996 0.000
H47.1 Papilloedema, unspecified
0.000 0.996 0.004
O44.1 Placenta praevia with haemorrhage
0.004 0.996 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.000 0.996 0.003
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.000 0.996 0.003
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.000 0.996 0.003
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.000 0.996 0.003
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.000 0.996 0.003
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.000 0.996 0.003
N84.2 Polyp of vagina
0.004 0.996 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.000 0.997 0.003
N60.3 Fibrosclerosis of breast
0.000 0.997 0.003
Z97.4 Presence of external hearing-aid
0.003 0.997 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.997 0.003
H47.0 Disorders of optic nerve, not elsewhere classified
0.000 0.997 0.003
O82.1 Delivery by emergency Caesarean section
0.000 0.997 0.003
Z11.1 Special screening examination for respiratory tuberculosis
0.000 0.997 0.003
H61.0 Perichondritis of external ear
0.003 0.997 0.000
B34.9 Viral infection, unspecified
0.003 0.997 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.000 0.997 0.003
H47.3 Other disorders of optic disk
0.000 0.997 0.003
C64 Malignant neoplasm of kidney, except renal pelvis
0.003 0.997 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.003 0.997 0.000
M05.0 Felty's syndrome
0.003 0.997 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.000 0.997 0.003
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.997 0.003
M05.8 Other seropositive rheumatoid arthritis
0.003 0.997 0.000
O14.9 Preeclampsia, unspecified
0.000 0.997 0.003
M05.2 Rheumatoid vasculitis
0.003 0.997 0.000
C50.4 Upper-outer quadrant of breast
0.000 0.997 0.003
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission
0.000 0.997 0.003
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.000 0.997 0.003
M05.1 Rheumatoid lung disease
0.003 0.997 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.997 0.003
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified
0.000 0.997 0.003
D70 Agranulocytosis
0.003 0.997 0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases
0.000 0.997 0.003
Z11.8 Special screening examination for other infectious and parasitic diseases
0.000 0.997 0.003
R22.4 Localised swelling, mass and lump, lower limb
0.000 0.997 0.003
F32.3 Severe depressive episode with psychotic symptoms
0.003 0.997 0.000
H47.2 Optic atrophy
0.000 0.997 0.003
U88 Agent resistant to multiple antibiotics
0.003 0.997 0.000
H47.7 Disorder of visual pathways, unspecified
0.000 0.997 0.002
H47.6 Disorders of visual cortex
0.000 0.997 0.002
H47.5 Disorders of other visual pathways
0.000 0.997 0.002
H47.4 Disorders of optic chiasm
0.000 0.997 0.002
M47.99 Spondylosis, unspecified (Site unspecified)
0.000 0.997 0.003
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.997 0.003
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.002 0.997 0.000
G93.9 Disorder of brain, unspecified
0.000 0.997 0.003
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.998 0.002
M05.09 Felty's syndrome (Site unspecified)
0.002 0.998 0.000
M05.08 Felty's syndrome (Other)
0.002 0.998 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.002 0.998 0.000
M05.06 Felty's syndrome (Lower leg)
0.002 0.998 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.002 0.998 0.000
M05.04 Felty's syndrome (Hand)
0.002 0.998 0.000
M05.03 Felty's syndrome (Forearm)
0.002 0.998 0.000
M05.02 Felty's syndrome (Upper arm)
0.002 0.998 0.000
M05.01 Felty's syndrome (Shoulder region)
0.002 0.998 0.000
M05.00 Felty's syndrome (Multiple sites)
0.002 0.998 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.002 0.998 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.002 0.998 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.002 0.998 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.002 0.998 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.002 0.998 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.002 0.998 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.002 0.998 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.002 0.998 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.002 0.998 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.002 0.998 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.998 0.002
M05.20 Rheumatoid vasculitis (Multiple sites)
0.002 0.998 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.002 0.998 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.002 0.998 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.002 0.998 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.002 0.998 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.002 0.998 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.002 0.998 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.002 0.998 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.002 0.998 0.000
M05.28 Rheumatoid vasculitis (Other)
0.002 0.998 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.002 0.998 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.002 0.998 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.002 0.998 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.002 0.998 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.002 0.998 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.002 0.998 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.002 0.998 0.000
T23.2 Burn of second degree of wrist and hand
0.002 0.998 0.000
M05.18 Rheumatoid lung disease (Other)
0.002 0.998 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.002 0.998 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.002 0.998 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.002 0.998 0.000
M05.14 Rheumatoid lung disease (Hand)
0.002 0.998 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.002 0.998 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.002 0.998 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.002 0.998 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.002 0.998 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.998 0.002
M05.29 Rheumatoid vasculitis (Site unspecified)
0.002 0.998 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.000 0.998 0.002
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.000 0.998 0.002
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.000 0.998 0.002
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.998 0.002
S91.3 Open wound of other parts of foot
0.002 0.998 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.998 0.002
N87.0 Mild cervical dysplasia
0.000 0.998 0.002
E23 Hypofunction and other disorders of pituitary gland
0.002 0.998 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.002 0.998 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.002 0.998 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.002 0.998 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.002 0.998 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.002 0.998 0.000
K56.0 Paralytic ileus
0.002 0.998 0.000
M20.3 Other deformity of hallux (acquired)
0.002 0.998 0.000
T51 Toxic effect of alcohol
0.002 0.998 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.000 0.998 0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.998 0.002
S02.20 Fracture of nasal bones (closed)
0.000 0.998 0.002
E83.4 Disorders of magnesium metabolism
0.002 0.998 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.000 0.998 0.002
E23.7 Disorder of pituitary gland, unspecified
0.002 0.998 0.000
H81.1 Benign paroxysmal vertigo
0.002 0.998 0.000
S52.5 Fracture of lower end of radius
0.002 0.998 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.002 0.998 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.002 0.998 0.000
E23.1 Drug-induced hypopituitarism
0.002 0.998 0.000
M62.88 Other specified disorders of muscle (Other)
0.002 0.998 0.000
Z13.9 Special screening examination, unspecified
0.000 0.998 0.002
G95.2 Cord compression, unspecified
0.002 0.998 0.000
M62.8 Other specified disorders of muscle
0.002 0.998 0.000
S72.40 Fracture of lower end of femur (closed)
0.002 0.998 0.000
B17.1 Acute hepatitis C
0.002 0.998 0.000
E23.2 Diabetes insipidus
0.002 0.998 0.000
T23 Burn and corrosion of wrist and hand
0.002 0.998 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.998 0.002
N94.6 Dysmenorrhoea, unspecified
0.000 0.998 0.002
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.002 0.998 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.002 0.998 0.000
M06.9 Rheumatoid arthritis, unspecified
0.002 0.998 0.000
T23.1 Burn of first degree of wrist and hand
0.002 0.998 0.000
O92.2 Other and unspecified disorders of breast associated with childbirth
0.002 0.998 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.002 0.998 0.000
K63.1 Perforation of intestine (nontraumatic)
0.002 0.998 0.000
M25.3 Other instability of joint
0.002 0.998 0.000
Z90.5 Acquired absence of kidney
0.002 0.998 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.998 0.002
O42.9 Premature rupture of membranes, unspecified
0.000 0.998 0.002
R84.5 Abnormal microbiological findings
0.000 0.998 0.002
M06.32 Rheumatoid nodule (Upper arm)
0.002 0.998 0.000
T59.8 Other specified gases, fumes and vapours
0.002 0.998 0.000
R01.1 Cardiac murmur, unspecified
0.002 0.998 0.000
T51.8 Other alcohols
0.002 0.998 0.000
T51.3 Fusel oil
0.002 0.998 0.000
T51.2 2-Propanol
0.002 0.998 0.000
T51.1 Methanol
0.002 0.998 0.000
Y79.8 Miscellaneous devices, not elsewhere classified
0.000 0.998 0.002
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices
0.000 0.998 0.002
Y79.0 Diagnostic and monitoring devices
0.000 0.998 0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.002 0.998 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.002 0.998 0.000
Z45.1 Adjustment and management of infusion pump
0.000 0.998 0.002
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.998 0.002
E23.6 Other disorders of pituitary gland
0.002 0.998 0.000
G82 Paraplegia and tetraplegia
0.000 0.998 0.002
M46 Other inflammatory spondylopathies
0.000 0.998 0.002
M62.87 Other specified disorders of muscle (Ankle and foot)
0.001 0.998 0.000
M62.84 Other specified disorders of muscle (Hand)
0.001 0.998 0.000
M06.3 Rheumatoid nodule
0.002 0.998 0.000
Q66.8 Other congenital deformities of feet
0.002 0.998 0.000
S61.8 Open wound of other parts of wrist and hand
0.000 0.998 0.002
T23.7 Corrosion of third degree of wrist and hand
0.001 0.998 0.000
T23.6 Corrosion of second degree of wrist and hand
0.001 0.998 0.000
T23.5 Corrosion of first degree of wrist and hand
0.001 0.998 0.000
T23.4 Corrosion of unspecified degree of wrist and hand
0.001 0.998 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.002 0.998 0.000
T21.2 Burn of second degree of trunk
0.002 0.998 0.000
Y79.3 Surgical instruments, materials and devices (including sutures)
0.000 0.998 0.001
M06 Other rheumatoid arthritis
0.002 0.998 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.002 0.998 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.001 0.998 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.002 0.998 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.001 0.998 0.000
T23.3 Burn of third degree of wrist and hand
0.002 0.998 0.000
M25.39 Other instability of joint (Site unspecified)
0.001 0.998 0.000
M25.38 Other instability of joint (Other)
0.001 0.998 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.001 0.998 0.000
M25.32 Other instability of joint (Upper arm)
0.001 0.998 0.000
M25.30 Other instability of joint (Multiple sites)
0.001 0.998 0.000
M25.52 Pain in joint (Upper arm)
0.002 0.998 0.000
S62.20 Fracture of first metacarpal bone (closed)
0.002 0.998 0.000
G95.8 Other specified diseases of spinal cord
0.000 0.998 0.002
J17.3 Pneumonia in parasitic diseases
0.000 0.998 0.002
J17.2 Pneumonia in mycoses
0.000 0.998 0.002
M46.4 Discitis, unspecified
0.000 0.998 0.002
M46.2 Osteomyelitis of vertebra
0.000 0.998 0.001
F31 Bipolar affective disorder
0.000 0.998 0.002
M46.44 Discitis, unspecified (Thoracic region)
0.000 0.998 0.001
C48.2 Peritoneum, unspecified
0.002 0.998 0.000
G91.9 Hydrocephalus, unspecified
0.002 0.998 0.000
M06.8 Other specified rheumatoid arthritis
0.001 0.998 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.000 0.998 0.002
M06.37 Rheumatoid nodule (Ankle and foot)
0.001 0.998 0.000
M25.33 Other instability of joint (Forearm)
0.001 0.998 0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)
0.001 0.998 0.000
O14.1 Severe preeclampsia
0.000 0.998 0.001
M25.36 Other instability of joint (Lower leg)
0.001 0.999 0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.000 0.999 0.001
D37.0 Lip, oral cavity and pharynx
0.000 0.999 0.001
M92.6 Juvenile osteochondrosis of tarsus
0.000 0.999 0.001
Q66.0 Talipes equinovarus
0.001 0.999 0.000
B34 Viral infection of unspecified site
0.001 0.999 0.000
M25.34 Other instability of joint (Hand)
0.001 0.999 0.000
D48.6 Breast
0.000 0.999 0.001
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.999 0.001
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.999 0.001
W18.3 Sports and athletics area
0.001 0.999 0.000
O44 Placenta praevia
0.001 0.999 0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)
0.001 0.999 0.000
G82.3 Flaccid tetraplegia
0.000 0.999 0.001
G82.0 Flaccid paraplegia
0.000 0.999 0.001
J15.4 Pneumonia due to other streptococci
0.001 0.999 0.000
M46.8 Other specified inflammatory spondylopathies
0.000 0.999 0.001
M46.5 Other infective spondylopathies
0.000 0.999 0.001
Q66 Congenital deformities of feet
0.001 0.999 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.001 0.999 0.000
M06.38 Rheumatoid nodule (Other)
0.001 0.999 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.001 0.999 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.001 0.999 0.000
M06.33 Rheumatoid nodule (Forearm)
0.001 0.999 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.001 0.999 0.000
G00.9 Bacterial meningitis, unspecified
0.000 0.999 0.001
M46.0 Spinal enthesopathy
0.000 0.999 0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.001 0.999 0.000
U81.0 Vancomycin resistant agent
0.001 0.999 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.001 0.999 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.000 0.999 0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.000 0.999 0.001
S42.20 Fracture of upper end of humerus (closed)
0.001 0.999 0.000
S52.80 Fracture of other parts of forearm (closed)
0.001 0.999 0.000
M06.2 Rheumatoid bursitis
0.001 0.999 0.000
M06.1 Adult-onset Still's disease
0.001 0.999 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.001 0.999 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.001 0.999 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.001 0.999 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.001 0.999 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.001 0.999 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.001 0.999 0.000
Y51.0 Anticholinesterase agents
0.001 0.999 0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.000 0.999 0.001
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.000 0.999 0.001
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.000 0.999 0.001
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.000 0.999 0.001
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.000 0.999 0.001
M46.22 Osteomyelitis of vertebra (Cervical region)
0.000 0.999 0.001
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.000 0.999 0.001
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.000 0.999 0.001
M46.49 Discitis, unspecified (Site unspecified)
0.000 0.999 0.001
M46.42 Discitis, unspecified (Cervical region)
0.000 0.999 0.001
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)
0.001 0.999 0.000
G82.5 Tetraplegia, unspecified
0.000 0.999 0.001
T59 Toxic effect of other gases, fumes and vapours
0.001 0.999 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.001 0.999 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.001 0.999 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.001 0.999 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.001 0.999 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.001 0.999 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.001 0.999 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.001 0.999 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.001 0.999 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.001 0.999 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.001 0.999 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M46.45 Discitis, unspecified (Thoracolumbar region)
0.000 0.999 0.001
M46.43 Discitis, unspecified (Cervicothoracic region)
0.000 0.999 0.001
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.000 0.999 0.001
M46.40 Discitis, unspecified (Multiple sites in spine)
0.000 0.999 0.001
S52.51 Fracture of lower end of radius (open)
0.001 0.999 0.000
O14.2 HELLP syndrome
0.000 0.999 0.001
M08 Juvenile arthritis
0.001 0.999 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.001 0.999 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.001 0.999 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.000 0.999 0.001
M08.2 Juvenile arthritis with systemic onset
0.001 0.999 0.000
Q67.5 Congenital deformity of spine
0.001 0.999 0.000
Q87.4 Marfan's syndrome
0.001 0.999 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.001 0.999 0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)
0.001 0.999 0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.001 0.999 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.001 0.999 0.000
M81.98 Osteoporosis, unspecified (Other)
0.000 0.999 0.001
K74.0 Hepatic fibrosis
0.000 0.999 0.001
M08.0 Juvenile rheumatoid arthritis
0.001 0.999 0.000
Q66.6 Other congenital valgus deformities of feet
0.001 0.999 0.000
M62 Other disorders of muscle
0.001 0.999 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.000 0.999 0.001
B34.3 Parvovirus infection, unspecified
0.001 0.999 0.000
B34.2 Coronavirus infection, unspecified
0.001 0.999 0.000
B34.1 Enterovirus infection, unspecified
0.001 0.999 0.000
B34.0 Adenovirus infection, unspecified
0.001 0.999 0.000
F31.8 Other bipolar affective disorders
0.000 0.999 0.001
N60.2 Fibroadenosis of breast
0.000 0.999 0.001
S72.4 Fracture of lower end of femur
0.001 0.999 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.000 0.999 0.001
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.000 0.999 0.001
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.000 0.999 0.001
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.000 0.999 0.001
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.000 0.999 0.001
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.000 0.999 0.001
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.000 0.999 0.001
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.000 0.999 0.001
M46.59 Other infective spondylopathies (Site unspecified)
0.000 0.999 0.001
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M46.57 Other infective spondylopathies (Lumbosacral region)
0.000 0.999 0.001
M46.56 Other infective spondylopathies (Lumbar region)
0.000 0.999 0.001
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.000 0.999 0.001
M46.54 Other infective spondylopathies (Thoracic region)
0.000 0.999 0.001
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.000 0.999 0.001
M46.52 Other infective spondylopathies (Cervical region)
0.000 0.999 0.001
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.000 0.999 0.001
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.000 0.999 0.001
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.000 0.999 0.001
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.000 0.999 0.001
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.000 0.999 0.001
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.000 0.999 0.001
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.000 0.999 0.001
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.000 0.999 0.001
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.000 0.999 0.001
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.000 0.999 0.001
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.000 0.999 0.001
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.999 0.001
G82.4 Spastic tetraplegia
0.000 0.999 0.001
J43.2 Centrilobular emphysema
0.000 0.999 0.001
K14.3 Hypertrophy of tongue papillae
0.001 0.999 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.001 0.999 0.000
Q66.7 Pes cavus
0.001 0.999 0.000
K14 Diseases of tongue
0.001 0.999 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.000 0.999 0.001
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M46.07 Spinal enthesopathy (Lumbosacral region)
0.000 0.999 0.001
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.000 0.999 0.001
M46.04 Spinal enthesopathy (Thoracic region)
0.000 0.999 0.001
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.000 0.999 0.001
M46.02 Spinal enthesopathy (Cervical region)
0.000 0.999 0.001
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.000 0.999 0.001
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.000 0.999 0.001
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.001 0.999 0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)
0.001 0.999 0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)
0.001 0.999 0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)
0.001 0.999 0.000
S52.61 Fracture of lower end of both ulna and radius (open)
0.001 0.999 0.000
D40.1 Testis
0.001 0.999 0.000
F31.7 Bipolar affective disorder, currently in remission
0.000 0.999 0.001
G95.0 Syringomyelia and syringobulbia
0.000 0.999 0.001
O36.5 Maternal care for poor foetal growth
0.000 0.999 0.001
Q66.9 Congenital deformity of feet, unspecified
0.001 0.999 0.000
Q66.5 Congenital pes planus
0.001 0.999 0.000
Q66.4 Talipes calcaneovalgus
0.001 0.999 0.000
Q66.1 Talipes calcaneovarus
0.001 0.999 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.001 0.999 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.001 0.999 0.000
M05-M14 Inflammatory polyarthropathies
0.001 0.999 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.001 0.999 0.000
M06.18 Adult-onset Still's disease (Other)
0.001 0.999 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.001 0.999 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.001 0.999 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.001 0.999 0.000
M06.14 Adult-onset Still's disease (Hand)
0.001 0.999 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.001 0.999 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.001 0.999 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.001 0.999 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.001 0.999 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.001 0.999 0.000
M06.28 Rheumatoid bursitis (Other)
0.001 0.999 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.001 0.999 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.001 0.999 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.001 0.999 0.000
M06.24 Rheumatoid bursitis (Hand)
0.001 0.999 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.001 0.999 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.001 0.999 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.001 0.999 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.001 0.999 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.001 0.999 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.000 0.999 0.001
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.000 0.999 0.001
G95.9 Disease of spinal cord, unspecified
0.000 0.999 0.001
K56.2 Volvulus
0.001 0.999 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.000 0.999 0.001
O32.8 Maternal care for other malpresentation of foetus
0.000 0.999 0.001
T51.9 Alcohol, unspecified
0.001 0.999 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.001 0.999 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.001 0.999 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.999 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.000 0.999 0.001
B34.8 Other viral infections of unspecified site
0.001 0.999 0.000
H61.9 Disorder of external ear, unspecified
0.001 0.999 0.000
H61.8 Other specified disorders of external ear
0.001 0.999 0.000
K14.1 Geographic tongue
0.001 0.999 0.000
M06.4 Inflammatory polyarthropathy
0.001 0.999 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.001 0.999 0.000
M62.0 Diastasis of muscle
0.001 0.999 0.000
T59.7 Carbon dioxide
0.001 0.999 0.000
T59.6 Hydrogen sulphide
0.001 0.999 0.000
T59.5 Fluorine gas and hydrogen fluoride
0.001 0.999 0.000
T59.4 Chlorine gas
0.001 0.999 0.000
T59.3 Lachrymogenic gas
0.001 0.999 0.000
T59.2 Formaldehyde
0.001 0.999 0.000
T59.1 Sulphur dioxide
0.001 0.999 0.000
T59.0 Nitrogen oxides
0.001 0.999 0.000
H61 Other disorders of external ear
0.001 0.999 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.999 0.001
M08.28 Juvenile arthritis with systemic onset (Other)
0.001 0.999 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.001 0.999 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.001 0.999 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.001 0.999 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.001 0.999 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.001 0.999 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.001 0.999 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.001 0.999 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.001 0.999 0.000
M25.44 Effusion of joint (Hand)
0.000 0.999 0.001
M79.16 Myalgia (Lower leg)
0.000 0.999 0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.999 0.001
E04.2 Non-toxic multinodular goitre
0.000 0.999 0.001
H61.3 Acquired stenosis of external ear canal
0.001 0.999 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.999 0.001
M08.9 Juvenile arthritis, unspecified
0.001 0.999 0.000
M08.8 Other juvenile arthritis
0.001 0.999 0.000
M08.4 Pauciarticular juvenile arthritis
0.001 0.999 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.001 0.999 0.000
M08.1 Juvenile ankylosing spondylitis
0.001 0.999 0.000
U84 Resistance to other antimicrobial drugs
0.001 0.999 0.000
U83 Resistance to other antibiotics
0.001 0.999 0.000
U82 Resistance to betalactam antibiotics
0.001 0.999 0.000
U85 Resistance to antineoplastic drugs
0.001 0.999 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.001 0.999 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.001 0.999 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.001 0.999 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.001 0.999 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.001 0.999 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.001 0.999 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.001 0.999 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.001 0.999 0.000
S72.10 Pertrochanteric fracture (closed)
0.001 0.999 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.999 0.001
M62.9 Disorder of muscle, unspecified
0.001 0.999 0.000
M62.4 Contracture of muscle
0.001 0.999 0.000
M62.3 Immobility syndrome (paraplegic)
0.001 0.999 0.000
M62.2 Ischaemic infarction of muscle
0.001 0.999 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.001 0.999 0.000
R85.5 Abnormal microbiological findings
0.000 0.999 0.001
R80 Isolated proteinuria
0.001 0.999 0.000
A48.1 Legionnaires' disease
0.000 0.999 0.001
I63.8 Other cerebral infarction
0.000 0.999 0.001
K14.6 Glossodynia
0.001 0.999 0.000
K14.5 Plicated tongue
0.001 0.999 0.000
K14.4 Atrophy of tongue papillae
0.001 0.999 0.000
K14.2 Median rhomboid glossitis
0.001 0.999 0.000
Q66.2 Metatarsus varus
0.001 0.999 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.001 0.999 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.000 0.999 0.001
J17 Pneumonia in diseases classified elsewhere
0.000 0.999 0.001
Q65 Congenital deformities of hip
0.001 0.999 0.000
T21 Burn and corrosion of trunk
0.001 0.999 0.000
M06.34 Rheumatoid nodule (Hand)
0.001 0.999 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.001 0.999 0.000
M62.08 Diastasis of muscle (Other)
0.001 0.999 0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)
0.001 0.999 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.999 0.001
K10.8 Other specified diseases of jaws
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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