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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs578776
log Bayes Factor = 12.2576
Chromosome 15   position 78,888,400  (GRCh37) Explore rs578776 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.005 0.995
J42 Unspecified chronic bronchitis
0.000 0.020 0.980
I71 Aortic aneurysm and dissection
0.000 0.037 0.963
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.040 0.960
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.043 0.957
I70 Atherosclerosis
0.000 0.058 0.942
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.059 0.941
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.085 0.915
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.111 0.889
I77 Other disorders of arteries and arterioles
0.000 0.114 0.886
I72 Other aneurysm
0.000 0.130 0.870
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.152 0.848
I70.0 Atherosclerosis of aorta
0.000 0.154 0.846
I77.1 Stricture of artery
0.000 0.164 0.836
J43.2 Centrilobular emphysema
0.000 0.193 0.807
I78 Diseases of capillaries
0.000 0.194 0.805
Chapter X Diseases of the respiratory system
0.000 0.199 0.801
I77.0 Arteriovenous fistula, acquired
0.000 0.205 0.795
J40 Bronchitis, not specified as acute or chronic
0.000 0.208 0.792
J90-J94 Other diseases of pleura
0.000 0.215 0.785
I73 Other peripheral vascular diseases
0.000 0.222 0.778
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.223 0.777
J92 Pleural plaque
0.000 0.234 0.766
I71.0 Dissection of aorta [any part]
0.000 0.236 0.764
I72.3 Aneurysm of iliac artery
0.000 0.254 0.746
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.256 0.744
J90 Pleural effusion, not elsewhere classified
0.000 0.258 0.742
I73.9 Peripheral vascular disease, unspecified
0.000 0.268 0.732
I72.8 Aneurysm of other specified arteries
0.000 0.272 0.728
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.273 0.727
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
J92.0 Pleural plaque with presence of asbestos
0.000 0.285 0.715
J86 Pyothorax
0.000 0.286 0.714
J92.9 Pleural plaque without asbestos
0.000 0.292 0.708
I72.0 Aneurysm of carotid artery
0.000 0.296 0.704
I72.9 Aneurysm of unspecified site
0.000 0.297 0.703
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.309 0.690
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.309 0.690
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.309 0.690
J86.9 Pyothorax without fistula
0.000 0.311 0.689
I77.2 Rupture of artery
0.000 0.314 0.686
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.323 0.677
I70.9 Generalised and unspecified atherosclerosis
0.000 0.324 0.675
I70.8 Atherosclerosis of other arteries
0.000 0.324 0.675
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.325 0.675
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.335 0.665
J60-J70 Lung diseases due to external agents
0.000 0.341 0.659
I78.1 Naevus, nonneoplastic
0.000 0.344 0.656
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.353 0.647
J95-J99 Other diseases of the respiratory system
0.000 0.357 0.643
J43.8 Other emphysema
0.000 0.358 0.641
I77.5 Necrosis of artery
0.000 0.365 0.635
I77.4 Coeliac artery compression syndrome
0.000 0.365 0.635
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.374 0.626
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.376 0.624
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.376 0.624
I72.1 Aneurysm of artery of upper extremity
0.000 0.376 0.624
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.394 0.606
I72.2 Aneurysm of renal artery
0.000 0.408 0.592
I78.8 Other diseases of capillaries
0.000 0.410 0.590
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.419 0.581
I70.1 Atherosclerosis of renal artery
0.000 0.421 0.579
I78.9 Disease of capillaries, unspecified
0.000 0.422 0.577
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.433 0.567
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.435 0.565
I77.3 Arterial fibromuscular dysplasia
0.000 0.447 0.552
J84 Other interstitial pulmonary diseases
0.000 0.451 0.549
J86.0 Pyothorax with fistula
0.000 0.462 0.538
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.463 0.537
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.464 0.536
J60 Coalworker's pneumoconiosis
0.000 0.471 0.529
J93 Pneumothorax
0.000 0.476 0.524
J64 Unspecified pneumoconiosis
0.000 0.481 0.519
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.506 0.494
J00-J06 Acute upper respiratory infections
0.000 0.509 0.491
J98 Other respiratory disorders
0.000 0.511 0.489
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.516 0.484
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.516 0.484
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.516 0.484
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.516 0.484
I60-I69 Cerebrovascular diseases
0.000 0.518 0.482
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.523 0.477
I79.1 Aortitis in diseases classified elsewhere
0.000 0.523 0.477
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.523 0.477
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.527 0.472
J66 Airway disease due to specific organic dust
0.000 0.527 0.472
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.527 0.472
J62 Pneumoconiosis due to dust containing silica
0.000 0.527 0.472
J65 Pneumoconiosis associated with tuberculosis
0.000 0.527 0.472
J91 Pleural effusion in conditions classified elsewhere
0.000 0.532 0.468
I73.8 Other specified peripheral vascular diseases
0.000 0.533 0.467
J00 Acute nasopharyngitis [common cold]
0.000 0.535 0.465
J85 Abscess of lung and mediastinum
0.000 0.536 0.464
J98.1 Pulmonary collapse
0.000 0.536 0.464
J96 Respiratory failure, not elsewhere classified
0.000 0.539 0.461
I77.8 Other specified disorders of arteries and arterioles
0.000 0.539 0.461
J69 Pneumonitis due to solids and liquids
0.000 0.542 0.458
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.542 0.458
Chapter IX Diseases of the circulatory system
0.000 0.542 0.458
I60 Subarachnoid haemorrhage
0.000 0.545 0.455
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.546 0.454
I74 Arterial embolism and thrombosis
0.000 0.550 0.450
J70 Respiratory conditions due to other external agents
0.000 0.561 0.439
I72.4 Aneurysm of artery of lower extremity
0.000 0.563 0.437
C67 Malignant neoplasm of bladder
0.000 0.571 0.429
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.585 0.415
I69 Sequelae of cerebrovascular disease
0.000 0.585 0.415
J93.8 Other pneumothorax
0.000 0.585 0.415
C67.6 Ureteric orifice
0.000 0.585 0.415
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.587 0.413
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.588 0.412
J98.9 Respiratory disorder, unspecified
0.000 0.588 0.412
J84.8 Other specified interstitial pulmonary diseases
0.000 0.588 0.412
J93.0 Spontaneous tension pneumothorax
0.000 0.590 0.410
C67.3 Anterior wall of bladder
0.000 0.591 0.409
C67.2 Lateral wall of bladder
0.000 0.592 0.408
I67 Other cerebrovascular diseases
0.000 0.592 0.408
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.595 0.405
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.596 0.404
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.597 0.403
J46 Status asthmaticus
0.000 0.599 0.400
I60.8 Other subarachnoid haemorrhage
0.000 0.601 0.398
I61 Intracerebral haemorrhage
0.000 0.603 0.397
J93.1 Other spontaneous pneumothorax
0.000 0.605 0.395
J84.0 Alveolar and parietoalveolar conditions
0.000 0.606 0.394
I26 Pulmonary embolism
0.000 0.608 0.392
I77.6 Arteritis, unspecified
0.000 0.608 0.392
C67.1 Dome of bladder
0.000 0.609 0.391
C64-C68 Malignant neoplasms of urinary tract
0.000 0.613 0.387
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.613 0.387
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.621 0.379
J69.8 Pneumonitis due to other solids and liquids
0.000 0.622 0.378
J02 Acute pharyngitis
0.000 0.626 0.374
J99.0 Rheumatoid lung disease
0.000 0.626 0.374
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.627 0.373
J94 Other pleural conditions
0.000 0.630 0.370
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.631 0.369
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.633 0.367
I67.1 Cerebral aneurysm, nonruptured
0.000 0.635 0.365
C67.4 Posterior wall of bladder
0.000 0.636 0.364
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.637 0.363
J95.8 Other postprocedural respiratory disorders
0.000 0.639 0.361
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.643 0.357
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.646 0.354
I67.9 Cerebrovascular disease, unspecified
0.000 0.646 0.354
J98.2 Interstitial emphysema
0.000 0.647 0.353
J98.4 Other disorders of lung
0.000 0.648 0.352
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.648 0.352
J98.3 Compensatory emphysema
0.000 0.649 0.351
I69.3 Sequelae of cerebral infarction
0.000 0.650 0.350
J85.0 Gangrene and necrosis of lung
0.000 0.656 0.344
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.656 0.343
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.657 0.343
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.661 0.339
J62.0 Pneumoconiosis due to talc dust
0.000 0.661 0.339
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.661 0.339
J63.5 Stannosis
0.000 0.661 0.339
J63.4 Siderosis
0.000 0.661 0.339
J63.3 Graphite fibrosis (of lung)
0.000 0.661 0.339
J63.2 Berylliosis
0.000 0.661 0.339
J63.1 Bauxite fibrosis (of lung)
0.000 0.661 0.339
J63.0 Aluminosis (of lung)
0.000 0.661 0.339
J66.8 Airway disease due to other specific organic dusts
0.000 0.661 0.339
J66.2 Cannabinosis
0.000 0.661 0.339
J66.1 Flax-dresser's disease
0.000 0.661 0.339
J66.0 Byssinosis
0.000 0.661 0.339
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.661 0.339
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.661 0.339
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.661 0.339
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.661 0.339
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.661 0.339
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.661 0.339
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.661 0.339
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.666 0.334
J85.3 Abscess of mediastinum
0.000 0.667 0.333
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.668 0.331
J96.9 Respiratory failure, unspecified
0.000 0.669 0.331
J96.1 Chronic respiratory failure
0.000 0.669 0.331
J96.0 Acute respiratory failure
0.000 0.669 0.331
J69.1 Pneumonitis due to oils and essences
0.000 0.671 0.329
I74.5 Embolism and thrombosis of iliac artery
0.000 0.672 0.328
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.673 0.327
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.673 0.327
C67.8 Overlapping lesion of bladder
0.000 0.674 0.326
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.677 0.323
J85.1 Abscess of lung with pneumonia
0.000 0.678 0.322
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.678 0.322
J09-J18 Influenza and pneumonia
0.000 0.679 0.321
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.680 0.320
I67.8 Other specified cerebrovascular diseases
0.000 0.680 0.320
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.681 0.319
C65 Malignant neoplasm of renal pelvis
0.000 0.681 0.319
J20-J22 Other acute lower respiratory infections
0.000 0.681 0.318
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.685 0.315
J70.8 Respiratory conditions due to other specified external agents
0.000 0.685 0.315
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.685 0.315
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.685 0.315
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.685 0.315
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.685 0.315
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.690 0.310
C67.5 Bladder neck
0.000 0.690 0.310
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.691 0.309
J98.8 Other specified respiratory disorders
0.000 0.692 0.308
C67.7 Urachus
0.000 0.693 0.307
I00-I02 Acute rheumatic fever
0.000 0.693 0.307
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.693 0.307
J01 Acute sinusitis
0.000 0.697 0.302
I62 Other nontraumatic intracranial haemorrhage
0.000 0.699 0.301
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.699 0.301
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.700 0.300
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.702 0.298
J95.5 Postprocedural subglottic stenosis
0.000 0.704 0.296
J95.4 Mendelson's syndrome
0.000 0.704 0.296
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.704 0.296
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.704 0.296
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.704 0.296
I28 Other diseases of pulmonary vessels
0.000 0.705 0.295
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.707 0.292
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.707 0.292
I67.5 Moyamoya disease
0.000 0.707 0.292
I67.4 Hypertensive encephalopathy
0.000 0.707 0.292
I67.3 Progressive vascular leukoencephalopathy
0.000 0.707 0.292
J81 Pulmonary oedema
0.000 0.712 0.288
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.713 0.287
J94.8 Other specified pleural conditions
0.000 0.713 0.287
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.714 0.286
I73.0 Raynaud's syndrome
0.000 0.716 0.284
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.718 0.282
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.719 0.281
J02.9 Acute pharyngitis, unspecified
0.000 0.720 0.280
J02.0 Streptococcal pharyngitis
0.000 0.720 0.280
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.721 0.279
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.721 0.279
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.730 0.270
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.731 0.269
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.731 0.268
I68.0 Cerebral amyloid angiopathy
0.000 0.733 0.267
J94.9 Pleural condition, unspecified
0.000 0.734 0.265
J94.0 Chylous effusion
0.000 0.734 0.265
J03 Acute tonsillitis
0.000 0.736 0.264
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.738 0.262
J85.2 Abscess of lung without pneumonia
0.000 0.739 0.261
C66 Malignant neoplasm of ureter
0.000 0.740 0.260
J98.6 Disorders of diaphragm
0.000 0.740 0.260
J10 Influenza due to identified influenza virus
0.000 0.741 0.259
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.742 0.258
I74.8 Embolism and thrombosis of other arteries
0.000 0.742 0.257
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.743 0.257
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.744 0.256
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.744 0.256
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.744 0.256
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.744 0.256
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.745 0.255
J47 Bronchiectasis
0.000 0.747 0.253
J04 Acute laryngitis and tracheitis
0.000 0.747 0.253
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.747 0.252
J67.7 Air-conditioner and humidifier lung
0.000 0.747 0.252
J67.6 Maple-bark-stripper's lung
0.000 0.747 0.252
J67.5 Mushroom-worker's lung
0.000 0.747 0.252
J67.4 Maltworker's lung
0.000 0.747 0.252
J67.3 Suberosis
0.000 0.747 0.252
J67.1 Bagassosis
0.000 0.747 0.252
J67.0 Farmer's lung
0.000 0.747 0.252
C67.0 Trigone of bladder
0.000 0.753 0.246
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.753 0.246
I61.8 Other intracerebral haemorrhage
0.000 0.756 0.244
J82 Pulmonary eosinophilia, not elsewhere classified
0.001 0.758 0.242
J18 Pneumonia, organism unspecified
0.000 0.761 0.239
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.761 0.239
J96.09 Acute respiratory failure; Type unspecified
0.000 0.763 0.237
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.763 0.237
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.763 0.237
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.763 0.237
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.763 0.237
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.763 0.237
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.763 0.237
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.763 0.237
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.763 0.237
I27 Other pulmonary heart diseases
0.000 0.763 0.237
C68.0 Urethra
0.000 0.766 0.234
J09 Influenza due to certain identified influenza virus
0.000 0.770 0.230
J21 Acute bronchiolitis
0.000 0.771 0.229
J69.0 Pneumonitis due to food and vomit
0.000 0.774 0.226
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.778 0.222
I02 Rheumatic chorea
0.000 0.780 0.220
I01 Rheumatic fever with heart involvement
0.000 0.780 0.220
J05.0 Acute obstructive laryngitis [croup]
0.000 0.780 0.220
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.782 0.218
J01.8 Other acute sinusitis
0.000 0.783 0.217
J01.4 Acute pansinusitis
0.000 0.783 0.217
J01.3 Acute sphenoidal sinusitis
0.000 0.783 0.217
J01.1 Acute frontal sinusitis
0.000 0.783 0.217
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.783 0.217
J18.1 Lobar pneumonia, unspecified
0.000 0.784 0.216
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.784 0.216
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.784 0.216
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.784 0.216
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.784 0.216
J01.0 Acute maxillary sinusitis
0.000 0.785 0.215
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.785 0.215
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.786 0.214
C68.9 Urinary organ, unspecified
0.000 0.786 0.213
C68.8 Overlapping lesion of urinary organs
0.000 0.786 0.213
C68.1 Paraurethral glands
0.000 0.786 0.213
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.787 0.213
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.788 0.211
I28.1 Aneurysm of pulmonary artery
0.000 0.788 0.211
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.788 0.211
I28.8 Other specified diseases of pulmonary vessels
0.000 0.789 0.210
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.790 0.210
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.791 0.209
I27.9 Pulmonary heart disease, unspecified
0.000 0.791 0.209
J01.9 Acute sinusitis, unspecified
0.000 0.793 0.207
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.794 0.205
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.795 0.204
J20 Acute bronchitis
0.000 0.795 0.205
J67.2 Bird fancier's lung
0.001 0.796 0.204
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.796 0.204
J17 Pneumonia in diseases classified elsewhere
0.000 0.797 0.203
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.799 0.201
I00 Rheumatic fever without mention of heart involvement
0.000 0.801 0.199
J12 Viral pneumonia, not elsewhere classified
0.000 0.803 0.197
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.808 0.192
I27.8 Other specified pulmonary heart diseases
0.000 0.809 0.191
J18.9 Pneumonia, unspecified
0.000 0.810 0.190
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.810 0.189
J03.0 Streptococcal tonsillitis
0.000 0.810 0.189
J95.0 Tracheostomy malfunction
0.000 0.813 0.187
J94.1 Fibrothorax
0.001 0.813 0.187
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.814 0.186
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.814 0.185
J01.2 Acute ethmoidal sinusitis
0.000 0.816 0.183
J04.2 Acute laryngotracheitis
0.000 0.818 0.181
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.822 0.178
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.822 0.178
J05.1 Acute epiglottitis
0.000 0.826 0.174
J18.2 Hypostatic pneumonia, unspecified
0.000 0.828 0.172
I62.1 Nontraumatic extradural haemorrhage
0.000 0.829 0.171
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.830 0.170
I27.1 Kyphoscoliotic heart disease
0.000 0.830 0.170
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.830 0.169
J15.8 Other bacterial pneumonia
0.000 0.832 0.167
J21.9 Acute bronchiolitis, unspecified
0.000 0.835 0.165
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.836 0.164
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.836 0.164
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.836 0.164
I99 Other and unspecified disorders of circulatory system
0.000 0.837 0.163
J15.5 Pneumonia due to Escherichia coli
0.000 0.837 0.163
J04.1 Acute tracheitis
0.000 0.837 0.162
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.838 0.162
J15.4 Pneumonia due to other streptococci
0.000 0.840 0.160
J18.8 Other pneumonia, organism unspecified
0.000 0.840 0.160
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.841 0.159
J06.0 Acute laryngopharyngitis
0.000 0.841 0.159
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.842 0.158
I01.8 Other acute rheumatic heart disease
0.000 0.842 0.158
I01.2 Acute rheumatic myocarditis
0.000 0.842 0.158
I01.1 Acute rheumatic endocarditis
0.000 0.842 0.158
I01.0 Acute rheumatic pericarditis
0.000 0.842 0.158
I02.9 Rheumatic chorea without heart involvement
0.000 0.842 0.158
I02.0 Rheumatic chorea with heart involvement
0.000 0.842 0.158
J20.8 Acute bronchitis due to other specified organisms
0.000 0.843 0.156
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.844 0.156
J94.2 Haemothorax
0.001 0.844 0.156
J15.3 Pneumonia due to streptococcus, group B
0.000 0.844 0.156
J80 Adult respiratory distress syndrome
0.001 0.845 0.154
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.847 0.153
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.847 0.153
I98.0 Cardiovascular syphilis
0.000 0.847 0.153
J16.0 Chlamydial pneumonia
0.000 0.847 0.153
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.847 0.153
J15.2 Pneumonia due to staphylococcus
0.000 0.847 0.153
J14 Pneumonia due to Haemophilus influenzae
0.000 0.850 0.150
J93.9 Pneumothorax, unspecified
0.000 0.851 0.149
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.852 0.147
J20.7 Acute bronchitis due to echovirus
0.000 0.853 0.147
J20.6 Acute bronchitis due to rhinovirus
0.000 0.853 0.147
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.853 0.147
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.853 0.147
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.853 0.147
J20.2 Acute bronchitis due to streptococcus
0.000 0.853 0.147
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.853 0.147
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.853 0.147
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.854 0.146
J12.8 Other viral pneumonia
0.000 0.858 0.141
J12.3 Human metapneumovirus pneumonia
0.000 0.858 0.141
J12.2 Parainfluenza virus pneumonia
0.000 0.858 0.141
J12.0 Adenoviral pneumonia
0.000 0.858 0.141
J45 Asthma
0.000 0.859 0.141
J15.9 Bacterial pneumonia, unspecified
0.000 0.859 0.140
J11 Influenza, virus not identified
0.001 0.864 0.135
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.864 0.135
J12.9 Viral pneumonia, unspecified
0.000 0.869 0.131
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.870 0.129
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.870 0.129
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.876 0.124
I05-I09 Chronic rheumatic heart diseases
0.000 0.877 0.123
I95 Hypotension
0.000 0.877 0.123
J12.1 Respiratory syncytial virus pneumonia
0.000 0.877 0.122
J17.3 Pneumonia in parasitic diseases
0.000 0.881 0.118
J04.0 Acute laryngitis
0.000 0.882 0.118
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.884 0.116
C67.9 Bladder, unspecified
0.000 0.886 0.114
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.888 0.112
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.888 0.112
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.890 0.110
I67.2 Cerebral atherosclerosis
0.000 0.890 0.109
J17.2 Pneumonia in mycoses
0.000 0.891 0.108
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.892 0.108
J20.9 Acute bronchitis, unspecified
0.000 0.893 0.107
I95.8 Other hypotension
0.000 0.894 0.106
J15.1 Pneumonia due to Pseudomonas
0.000 0.895 0.104
I95.1 Orthostatic hypotension
0.000 0.896 0.104
I97.1 Other functional disturbances following cardiac surgery
0.000 0.896 0.104
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.896 0.103
J45.8 Mixed asthma
0.000 0.898 0.101
J03.9 Acute tonsillitis, unspecified
0.000 0.899 0.101
I09 Other rheumatic heart diseases
0.000 0.900 0.100
I63 Cerebral infarction
0.000 0.902 0.098
I97.0 Postcardiotomy syndrome
0.000 0.902 0.097
J11.8 Influenza with other manifestations, virus not identified
0.001 0.902 0.097
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.907 0.093
I06 Rheumatic aortic valve diseases
0.000 0.912 0.087
J11.0 Influenza with pneumonia, virus not identified
0.001 0.916 0.083
I65.1 Occlusion and stenosis of basilar artery
0.000 0.917 0.083
I09.9 Rheumatic heart disease, unspecified
0.000 0.917 0.083
J45.1 Nonallergic asthma
0.000 0.920 0.080
I27.2 Other secondary pulmonary hypertension
0.000 0.921 0.079
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.922 0.077
I10-I15 Hypertensive diseases
0.000 0.925 0.075
I95.0 Idiopathic hypotension
0.000 0.928 0.072
I09.8 Other specified rheumatic heart diseases
0.000 0.928 0.072
I09.2 Chronic rheumatic pericarditis
0.000 0.928 0.072
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.928 0.072
I09.0 Rheumatic myocarditis
0.000 0.928 0.072
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.928 0.071
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.929 0.070
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.929 0.070
I07 Rheumatic tricuspid valve diseases
0.000 0.930 0.070
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.937 0.063
I06.8 Other rheumatic aortic valve diseases
0.000 0.937 0.063
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.937 0.063
I06.1 Rheumatic aortic insufficiency
0.000 0.937 0.063
I06.0 Rheumatic aortic stenosis
0.000 0.938 0.062
I05 Rheumatic mitral valve diseases
0.000 0.943 0.057
I13 Hypertensive heart and renal disease
0.000 0.946 0.054
I15 Secondary hypertension
0.000 0.947 0.053
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.949 0.051
I07.9 Tricuspid valve disease, unspecified
0.000 0.950 0.050
I07.8 Other tricuspid valve diseases
0.000 0.950 0.050
I07.2 Tricuspid stenosis with insufficiency
0.000 0.950 0.050
I07.0 Tricuspid stenosis
0.000 0.950 0.050
I87 Other disorders of veins
0.000 0.952 0.048
S02.10 Fracture of base of skull (closed)
0.048 0.952 0.000
S02 Fracture of skull and facial bones
0.048 0.952 0.000
S02.1 Fracture of base of skull
0.047 0.953 0.000
I27.0 Primary pulmonary hypertension
0.000 0.953 0.047
I05.1 Rheumatic mitral insufficiency
0.000 0.953 0.047
S02.7 Multiple fractures involving skull and facial bones
0.046 0.954 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.954 0.046
I87.1 Compression of vein
0.000 0.954 0.046
S02.70 Multiple fractures involving skull and facial bones (closed)
0.046 0.954 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.954 0.046
I15.1 Hypertension secondary to other renal disorders
0.000 0.955 0.045
S02.5 Fracture of tooth
0.045 0.955 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.956 0.044
J22 Unspecified acute lower respiratory infection
0.000 0.956 0.044
S02.50 Fracture of tooth (closed)
0.043 0.957 0.000
S02.0 Fracture of vault of skull
0.043 0.957 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.042 0.958 0.000
S02.3 Fracture of orbital floor
0.042 0.958 0.000
I05.8 Other mitral valve diseases
0.000 0.959 0.041
I81 Portal vein thrombosis
0.000 0.959 0.041
J18.0 Bronchopneumonia, unspecified
0.001 0.959 0.040
I88 Nonspecific lymphadenitis
0.000 0.961 0.039
S02.00 Fracture of vault of skull (closed)
0.039 0.961 0.000
I87.8 Other specified disorders of veins
0.000 0.961 0.039
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.961 0.039
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.961 0.039
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.961 0.039
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.961 0.039
I11 Hypertensive heart disease
0.000 0.961 0.039
I15.8 Other secondary hypertension
0.000 0.962 0.038
I15.2 Hypertension secondary to endocrine disorders
0.000 0.962 0.038
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.962 0.038
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.962 0.037
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.038 0.962 0.000
S02.30 Fracture of orbital floor (closed)
0.037 0.963 0.000
I87.0 Postphlebitic syndrome
0.000 0.965 0.035

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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