TreeWAS – Variant ID: rs585362

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.011	0.989
E78.5 Hyperlipidaemia, unspecified	0.000	0.012	0.988
I25.1 Atherosclerotic heart disease	0.000	0.161	0.839
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.164	0.836
I25 Chronic ischaemic heart disease	0.000	0.169	0.831
E78.1 Pure hyperglyceridaemia	0.000	0.201	0.799
E78.8 Other disorders of lipoprotein metabolism	0.000	0.254	0.746
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.290	0.710
E78.6 Lipoprotein deficiency	0.000	0.291	0.709
E78.3 Hyperchylomicronaemia	0.000	0.291	0.709
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.306	0.694
M48.06 Spinal stenosis (Lumbar region)	0.000	0.326	0.674
E78.2 Mixed hyperlipidaemia	0.000	0.327	0.673
M48.0 Spinal stenosis	0.000	0.331	0.669
I25.3 Aneurysm of heart	0.000	0.335	0.665
M48.09 Spinal stenosis (Site unspecified)	0.000	0.361	0.639
I25.2 Old myocardial infarction	0.000	0.378	0.622
M48.02 Spinal stenosis (Cervical region)	0.000	0.391	0.609
I25.6 Silent myocardial ischaemia	0.000	0.404	0.596
I25.4 Coronary artery aneurysm	0.000	0.418	0.581
E78.4 Other hyperlipidaemia	0.000	0.453	0.547
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.473	0.526
M48.04 Spinal stenosis (Thoracic region)	0.000	0.483	0.517
I25.5 Ischaemic cardiomyopathy	0.000	0.483	0.517
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.490	0.510
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.520	0.480
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.520	0.480
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.520	0.480
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.520	0.480
M48 Other spondylopathies	0.000	0.523	0.477
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.580	0.420
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.613	0.387
M48.9 Spondylopathy, unspecified	0.000	0.658	0.342
M48.8 Other specified spondylopathies	0.000	0.658	0.342
M48.4 Fatigue fracture of vertebra	0.000	0.658	0.342
M48.3 Traumatic spondylopathy	0.000	0.658	0.342
M48.2 Kissing spine	0.000	0.658	0.342
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.658	0.342
Z93.2 Ileostomy status	0.329	0.671	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.694	0.305
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.699	0.301
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.699	0.301
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.699	0.301
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.699	0.301
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.699	0.301
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.699	0.301
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.699	0.301
Z93 Artificial opening status	0.295	0.705	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.727	0.273
Z93.6 Other artificial openings of urinary tract status	0.269	0.731	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.267	0.733	0.000
Z93.5 Cystostomy status	0.266	0.734	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.755	0.245
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.755	0.245
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.755	0.245
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.755	0.245
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.755	0.245
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.755	0.245
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.755	0.245
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.755	0.245
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.755	0.245
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.755	0.245
M48.29 Kissing spine (Site unspecified)	0.000	0.755	0.245
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.755	0.245
M48.27 Kissing spine (Lumbosacral region)	0.000	0.755	0.245
M48.26 Kissing spine (Lumbar region)	0.000	0.755	0.245
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.755	0.245
M48.24 Kissing spine (Thoracic region)	0.000	0.755	0.245
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.755	0.245
M48.22 Kissing spine (Cervical region)	0.000	0.755	0.245
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.755	0.245
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.755	0.245
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.755	0.245
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.755	0.245
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.755	0.245
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.755	0.245
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.755	0.245
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.755	0.245
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.755	0.245
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.755	0.245
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.755	0.245
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.755	0.245
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.755	0.245
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.755	0.245
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.755	0.245
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.755	0.245
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.755	0.245
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.755	0.245
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.755	0.245
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.755	0.245
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.755	0.245
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.755	0.245
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.755	0.245
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.755	0.245
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.755	0.245
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.755	0.245
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.755	0.245
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.755	0.245
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.755	0.245
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.755	0.245
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.755	0.245
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.755	0.245
M48.99 Spondylopathy, unspecified (Site unspecified)	0.000	0.755	0.245
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.755	0.245
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.755	0.245
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.755	0.245
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.755	0.245
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.755	0.245
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.755	0.245
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.755	0.245
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.755	0.245
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.755	0.245
Z93.3 Colostomy status	0.245	0.755	0.000
I20-I25 Ischaemic heart diseases	0.000	0.755	0.245
I20 Angina pectoris	0.000	0.762	0.238
I20.9 Angina pectoris, unspecified	0.000	0.762	0.238
Z93.9 Artificial opening status, unspecified	0.224	0.776	0.000
I20.0 Unstable angina	0.000	0.801	0.199
Z93.8 Other artificial opening status	0.190	0.810	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.816	0.184
Z93.1 Gastrostomy status	0.159	0.841	0.000
I20.8 Other forms of angina pectoris	0.000	0.843	0.157
K91.3 Postoperative intestinal obstruction	0.157	0.843	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.157	0.843	0.000
K91.4 Colostomy and enterostomy malfunction	0.153	0.847	0.000
M45-M49 Spondylopathies	0.000	0.851	0.149
K91.0 Vomiting following gastro-intestinal surgery	0.143	0.857	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.859	0.141
K91.2 Postsurgical malabsorption, not elsewhere classified	0.139	0.861	0.000
Z93.0 Tracheostomy status	0.136	0.864	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.868	0.132
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.868	0.132
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.868	0.132
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.868	0.132
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.868	0.132
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.868	0.132
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.868	0.132
K91.5 Postcholecystectomy syndrome	0.128	0.872	0.000
M49 Spondylopathies in diseases classified elsewhere	0.000	0.876	0.124
M45 Ankylosing spondylitis	0.000	0.888	0.112
K91.1 Postgastric surgery syndromes	0.109	0.890	0.000
M46 Other inflammatory spondylopathies	0.000	0.891	0.109
K91.9 Postprocedural disorder of digestive system, unspecified	0.108	0.892	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.894	0.106
I24 Other acute ischaemic heart diseases	0.000	0.898	0.102
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.907	0.093
I20.1 Angina pectoris with documented spasm	0.000	0.908	0.092
K90-K93 Other diseases of the digestive system	0.089	0.911	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.911	0.089
M49.4 Neuropathic spondylopathy	0.000	0.911	0.089
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.911	0.089
M49.2 Enterobacterial spondylitis	0.000	0.911	0.089
M49.1 Brucella spondylitis	0.000	0.911	0.089
M49.0 Tuberculosis of spine	0.000	0.911	0.089
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.911	0.089
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.914	0.086
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.915	0.085
K92 Other diseases of digestive system	0.084	0.916	0.000
M46.4 Discitis, unspecified	0.000	0.917	0.083
K92.9 Disease of digestive system, unspecified	0.081	0.919	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.919	0.080
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.919	0.080
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.919	0.080
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.919	0.080
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.919	0.080
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.919	0.080
K92.0 Haematemesis	0.080	0.920	0.000
M46.8 Other specified inflammatory spondylopathies	0.000	0.922	0.078
M46.5 Other infective spondylopathies	0.000	0.922	0.078
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.922	0.078
M46.2 Osteomyelitis of vertebra	0.000	0.922	0.078
M46.0 Spinal enthesopathy	0.000	0.922	0.078
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.000	0.924	0.076
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.000	0.924	0.076
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.000	0.924	0.076
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.000	0.924	0.076
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.000	0.924	0.076
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.000	0.924	0.076
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.000	0.924	0.076
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.000	0.924	0.076
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.000	0.924	0.076
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.925	0.075
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.926	0.074
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.926	0.074
I24.1 Dressler's syndrome	0.000	0.926	0.073
K92.8 Other specified diseases of digestive system	0.073	0.927	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.927	0.072
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.930	0.070
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.932	0.068
I24.8 Other forms of acute ischaemic heart disease	0.000	0.933	0.066
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.934	0.065
M49.09 Tuberculosis of spine (Site unspecified)	0.000	0.936	0.064
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)	0.000	0.936	0.064
M49.07 Tuberculosis of spine (Lumbosacral region)	0.000	0.936	0.064
M49.06 Tuberculosis of spine (Lumbar region)	0.000	0.936	0.064
M49.05 Tuberculosis of spine (Thoracolumbar region)	0.000	0.936	0.064
M49.04 Tuberculosis of spine (Thoracic region)	0.000	0.936	0.064
M49.03 Tuberculosis of spine (Cervicothoracic region)	0.000	0.936	0.064
M49.02 Tuberculosis of spine (Cervical region)	0.000	0.936	0.064
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)	0.000	0.936	0.064
M49.00 Tuberculosis of spine (Multiple sites in spine)	0.000	0.936	0.064
M49.19 Brucella spondylitis (Site unspecified)	0.000	0.936	0.064
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)	0.000	0.936	0.064
M49.17 Brucella spondylitis (Lumbosacral region)	0.000	0.936	0.064
M49.16 Brucella spondylitis (Lumbar region)	0.000	0.936	0.064
M49.15 Brucella spondylitis (Thoracolumbar region)	0.000	0.936	0.064
M49.14 Brucella spondylitis (Thoracic region)	0.000	0.936	0.064
M49.13 Brucella spondylitis (Cervicothoracic region)	0.000	0.936	0.064
M49.12 Brucella spondylitis (Cervical region)	0.000	0.936	0.064
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)	0.000	0.936	0.064
M49.10 Brucella spondylitis (Multiple sites in spine)	0.000	0.936	0.064
M49.29 Enterobacterial spondylitis (Site unspecified)	0.000	0.936	0.064
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)	0.000	0.936	0.064
M49.27 Enterobacterial spondylitis (Lumbosacral region)	0.000	0.936	0.064
M49.26 Enterobacterial spondylitis (Lumbar region)	0.000	0.936	0.064
M49.25 Enterobacterial spondylitis (Thoracolumbar region)	0.000	0.936	0.064
M49.24 Enterobacterial spondylitis (Thoracic region)	0.000	0.936	0.064
M49.23 Enterobacterial spondylitis (Cervicothoracic region)	0.000	0.936	0.064
M49.22 Enterobacterial spondylitis (Cervical region)	0.000	0.936	0.064
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)	0.000	0.936	0.064
M49.20 Enterobacterial spondylitis (Multiple sites in spine)	0.000	0.936	0.064
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)	0.000	0.936	0.064
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)	0.000	0.936	0.064
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)	0.000	0.936	0.064
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)	0.000	0.936	0.064
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)	0.000	0.936	0.064
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)	0.000	0.936	0.064
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)	0.000	0.936	0.064
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)	0.000	0.936	0.064
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)	0.000	0.936	0.064
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)	0.000	0.936	0.064
M49.49 Neuropathic spondylopathy (Site unspecified)	0.000	0.936	0.064
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.936	0.064
M49.47 Neuropathic spondylopathy (Lumbosacral region)	0.000	0.936	0.064
M49.46 Neuropathic spondylopathy (Lumbar region)	0.000	0.936	0.064
M49.45 Neuropathic spondylopathy (Thoracolumbar region)	0.000	0.936	0.064
M49.44 Neuropathic spondylopathy (Thoracic region)	0.000	0.936	0.064
M49.43 Neuropathic spondylopathy (Cervicothoracic region)	0.000	0.936	0.064
M49.42 Neuropathic spondylopathy (Cervical region)	0.000	0.936	0.064
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)	0.000	0.936	0.064
M49.40 Neuropathic spondylopathy (Multiple sites in spine)	0.000	0.936	0.064
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)	0.000	0.936	0.064
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)	0.000	0.936	0.064
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)	0.000	0.936	0.064
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)	0.000	0.936	0.064
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)	0.000	0.936	0.064
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)	0.000	0.936	0.064
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)	0.000	0.936	0.064
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)	0.000	0.936	0.064
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)	0.000	0.936	0.064
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)	0.000	0.936	0.064
K93 Disorders of other digestive organs in diseases classified elsewhere	0.064	0.936	0.000
I22 Subsequent myocardial infarction	0.000	0.938	0.062
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.939	0.061
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.939	0.061
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.939	0.061
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.939	0.061
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.939	0.061
M46.49 Discitis, unspecified (Site unspecified)	0.000	0.940	0.060
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.000	0.940	0.060
M46.47 Discitis, unspecified (Lumbosacral region)	0.000	0.940	0.060
M46.45 Discitis, unspecified (Thoracolumbar region)	0.000	0.940	0.060
M46.43 Discitis, unspecified (Cervicothoracic region)	0.000	0.940	0.060
M46.42 Discitis, unspecified (Cervical region)	0.000	0.940	0.060
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.000	0.940	0.060
M46.40 Discitis, unspecified (Multiple sites in spine)	0.000	0.940	0.060
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.941	0.058
M46.09 Spinal enthesopathy (Site unspecified)	0.000	0.944	0.056
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.000	0.944	0.056
M46.07 Spinal enthesopathy (Lumbosacral region)	0.000	0.944	0.056
M46.06 Spinal enthesopathy (Lumbar region)	0.000	0.944	0.056
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.000	0.944	0.056
M46.04 Spinal enthesopathy (Thoracic region)	0.000	0.944	0.056
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.000	0.944	0.056
M46.02 Spinal enthesopathy (Cervical region)	0.000	0.944	0.056
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.000	0.944	0.056
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.000	0.944	0.056
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.000	0.944	0.056
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.000	0.944	0.056
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.000	0.944	0.056
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.000	0.944	0.056
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.000	0.944	0.056
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.000	0.944	0.056
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.000	0.944	0.056
M46.22 Osteomyelitis of vertebra (Cervical region)	0.000	0.944	0.056
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.000	0.944	0.056
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.000	0.944	0.056
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.000	0.944	0.056
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.000	0.944	0.056
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.000	0.944	0.056
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.000	0.944	0.056
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.000	0.944	0.056
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.000	0.944	0.056
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.000	0.944	0.056
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.000	0.944	0.056
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.000	0.944	0.056
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.000	0.944	0.056
M46.59 Other infective spondylopathies (Site unspecified)	0.000	0.944	0.056
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.000	0.944	0.056
M46.57 Other infective spondylopathies (Lumbosacral region)	0.000	0.944	0.056
M46.56 Other infective spondylopathies (Lumbar region)	0.000	0.944	0.056
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.000	0.944	0.056
M46.54 Other infective spondylopathies (Thoracic region)	0.000	0.944	0.056
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.000	0.944	0.056
M46.52 Other infective spondylopathies (Cervical region)	0.000	0.944	0.056
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.000	0.944	0.056
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.000	0.944	0.056
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.000	0.944	0.056
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.000	0.944	0.056
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.000	0.944	0.056
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.000	0.944	0.056
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.000	0.944	0.056
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.000	0.944	0.056
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.000	0.944	0.056
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.000	0.944	0.056
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.000	0.944	0.056
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.000	0.944	0.056
M46.44 Discitis, unspecified (Thoracic region)	0.000	0.945	0.055
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.947	0.052
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.000	0.953	0.047
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.000	0.953	0.047
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.000	0.953	0.047
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.000	0.953	0.047
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.000	0.953	0.047
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.000	0.953	0.047
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.000	0.953	0.047
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.000	0.953	0.047
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.000	0.953	0.047
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.046	0.954	0.000
K93.1 Megacolon in Chagas' disease	0.046	0.954	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.046	0.954	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.043	0.957	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.958	0.042
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.039	0.961	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.039	0.961	0.000
Q50-Q56 Congenital malformations of genital organs	0.037	0.963	0.000
Q60-Q64 Congenital malformations of the urinary system	0.036	0.964	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.965	0.035
I22.8 Subsequent myocardial infarction of other sites	0.000	0.965	0.035
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.965	0.034
Q66 Congenital deformities of feet	0.034	0.966	0.000
Q00-Q07 Congenital malformations of the nervous system	0.034	0.966	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.033	0.967	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.032	0.968	0.000
Q61 Cystic kidney disease	0.032	0.968	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.032	0.968	0.000
H16 Keratitis	0.032	0.968	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.032	0.968	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.031	0.969	0.000
Q07 Other congenital malformations of nervous system	0.031	0.969	0.000
Q53 Undescended testicle	0.031	0.969	0.000
H17 Corneal scars and opacities	0.030	0.969	0.000
Q78 Other osteochondrodysplasias	0.030	0.970	0.000
Q07.0 Arnold-Chiari syndrome	0.030	0.970	0.000
Q63 Other congenital malformations of kidney	0.030	0.970	0.000
Q74 Other congenital malformations of limb(s)	0.030	0.970	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.970	0.029
Q61.3 Polycystic kidney, unspecified	0.030	0.970	0.000
Q52 Other congenital malformations of female genitalia	0.029	0.971	0.000
Q55 Other congenital malformations of male genital organs	0.029	0.971	0.000
K90 Intestinal malabsorption	0.029	0.971	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.029	0.971	0.000
H16.0 Corneal ulcer	0.029	0.971	0.000
H17.8 Other corneal scars and opacities	0.029	0.971	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.028	0.972	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.028	0.972	0.000
Q35-Q37 Cleft lip and cleft palate	0.028	0.972	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.028	0.972	0.000
Q54 Hypospadias	0.028	0.972	0.000
Q51 Congenital malformations of uterus and cervix	0.028	0.972	0.000
Q76 Congenital malformations of spine and bony thorax	0.028	0.972	0.000
Q66.6 Other congenital valgus deformities of feet	0.028	0.972	0.000
Q25 Congenital malformations of great arteries	0.028	0.972	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.028	0.972	0.000
Q75 Other congenital malformations of skull and face bones	0.028	0.972	0.000
Q73 Reduction defects of unspecified limb	0.028	0.972	0.000
Q72 Reduction defects of lower limb	0.028	0.972	0.000
Q71 Reduction defects of upper limb	0.028	0.972	0.000
Q70 Syndactyly	0.028	0.972	0.000
Q69 Polydactyly	0.028	0.972	0.000
Q68 Other congenital musculoskeletal deformities	0.028	0.972	0.000
H18 Other disorders of cornea	0.028	0.972	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.972	0.027
Q79.6 Ehlers-Danlos syndrome	0.027	0.973	0.000
Q67.5 Congenital deformity of spine	0.027	0.973	0.000
Q80-Q89 Other congenital malformations	0.027	0.973	0.000
Q66.8 Other congenital deformities of feet	0.027	0.973	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.027	0.973	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.027	0.973	0.000
Q53.1 Undescended testicle, unilateral	0.027	0.973	0.000
Q66.3 Other congenital varus deformities of feet	0.027	0.973	0.000
Q27 Other congenital malformations of peripheral vascular system	0.027	0.973	0.000
Q65 Congenital deformities of hip	0.026	0.974	0.000
Q17 Other congenital malformations of ear	0.026	0.974	0.000
Q66.0 Talipes equinovarus	0.026	0.974	0.000
H16.8 Other keratitis	0.026	0.974	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.026	0.974	0.000
H21 Other disorders of iris and ciliary body	0.026	0.974	0.000
H16.2 Keratoconjunctivitis	0.026	0.974	0.000
Q66.2 Metatarsus varus	0.025	0.974	0.000
H16.3 Interstitial and deep keratitis	0.025	0.975	0.000
H17.9 Corneal scar and opacity, unspecified	0.025	0.975	0.000
Q24 Other congenital malformations of heart	0.025	0.975	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.025	0.975	0.000
Q61.4 Renal dysplasia	0.025	0.975	0.000
Q64 Other congenital malformations of urinary system	0.025	0.975	0.000
H18.8 Other specified disorders of cornea	0.025	0.975	0.000
Q61.9 Cystic kidney disease, unspecified	0.025	0.975	0.000
Q43 Other congenital malformations of intestine	0.025	0.975	0.000
Q66.9 Congenital deformity of feet, unspecified	0.025	0.975	0.000
Q66.7 Pes cavus	0.025	0.975	0.000
Q66.5 Congenital pes planus	0.025	0.975	0.000
Q66.4 Talipes calcaneovalgus	0.025	0.975	0.000
Q66.1 Talipes calcaneovarus	0.025	0.975	0.000
H20 Iridocyclitis	0.025	0.975	0.000
Q67.6 Pectus excavatum	0.025	0.975	0.000
Q28 Other congenital malformations of circulatory system	0.024	0.976	0.000
Q06 Other congenital malformations of spinal cord	0.024	0.976	0.000
Q04 Other congenital malformations of brain	0.024	0.976	0.000
Q03 Congenital hydrocephalus	0.024	0.976	0.000
Q01 Encephalocele	0.024	0.976	0.000
Q00 Anencephaly and similar malformations	0.024	0.976	0.000
Q02 Microcephaly	0.024	0.976	0.000
H15 Disorders of sclera	0.024	0.976	0.000
Q61.2 Polycystic kidney, adult type	0.024	0.976	0.000
Q54.9 Hypospadias, unspecified	0.024	0.976	0.000
Q52.5 Fusion of labia	0.024	0.976	0.000
Q78.0 Osteogenesis imperfecta	0.024	0.976	0.000
Q55.6 Other congenital malformations of penis	0.024	0.976	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.024	0.976	0.000
Q26 Congenital malformations of great veins	0.024	0.976	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.024	0.976	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.024	0.976	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.976	0.023
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.023	0.976	0.000
H18.9 Disorder of cornea, unspecified	0.024	0.976	0.000
Q25.3 Stenosis of aorta	0.023	0.976	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.023	0.976	0.000
Q67.8 Other congenital deformities of chest	0.023	0.977	0.000
Q67.7 Pectus carinatum	0.023	0.977	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.023	0.977	0.000
Q67.3 Plagiocephaly	0.023	0.977	0.000
Q67.2 Dolichocephaly	0.023	0.977	0.000
Q67.1 Compression facies	0.023	0.977	0.000
Q67.0 Facial asymmetry	0.023	0.977	0.000
Q12 Congenital lens malformations	0.023	0.977	0.000
Q61.8 Other cystic kidney diseases	0.023	0.977	0.000
Q61.1 Polycystic kidney, infantile type	0.023	0.977	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.023	0.977	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.023	0.977	0.000
Q79.5 Other congenital malformations of abdominal wall	0.023	0.977	0.000
Q79.4 Prune belly syndrome	0.023	0.977	0.000
Q79.3 Gastroschisis	0.023	0.977	0.000
Q79.2 Exomphalos	0.023	0.977	0.000
Q79.1 Other congenital malformations of diaphragm	0.023	0.977	0.000
Q79.0 Congenital diaphragmatic hernia	0.023	0.977	0.000
Q74.1 Congenital malformation of knee	0.023	0.977	0.000
H16.4 Corneal neovascularisation	0.023	0.977	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.023	0.977	0.000
Q15 Other congenital malformations of eye	0.023	0.977	0.000
Q14 Congenital malformations of posterior segment of eye	0.023	0.977	0.000
Q13 Congenital malformations of anterior segment of eye	0.023	0.977	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.023	0.977	0.000
Q63.0 Accessory kidney	0.023	0.977	0.000
Q51.4 Unicornate uterus	0.023	0.977	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.023	0.977	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.023	0.977	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.023	0.977	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.023	0.977	0.000
Q07.8 Other specified congenital malformations of nervous system	0.023	0.977	0.000
Q61.5 Medullary cystic kidney	0.023	0.977	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.977	0.023
H16.9 Keratitis, unspecified	0.022	0.977	0.000
Q53.9 Undescended testicle, unspecified	0.022	0.977	0.000
Q53.2 Undescended testicle, bilateral	0.022	0.977	0.000
Q53.0 Ectopic testis	0.022	0.977	0.000
Q23 Congenital malformations of aortic and mitral valves	0.022	0.977	0.000
Q43.0 Meckel's diverticulum	0.022	0.978	0.000
Q17.5 Prominent ear	0.022	0.978	0.000
Q51.2 Other doubling of uterus	0.022	0.978	0.000
H17.1 Other central corneal opacity	0.022	0.978	0.000
H17.0 Adherent leukoma	0.022	0.978	0.000
Q63.2 Ectopic kidney	0.022	0.978	0.000
Q18 Other congenital malformations of face and neck	0.022	0.978	0.000
K90.9 Intestinal malabsorption, unspecified	0.022	0.978	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.022	0.978	0.000
Q78.8 Other specified osteochondrodysplasias	0.022	0.978	0.000
Q78.6 Multiple congenital exostoses	0.022	0.978	0.000
Q78.5 Metaphyseal dysplasia	0.022	0.978	0.000
Q78.4 Enchondromatosis	0.022	0.978	0.000
Q78.3 Progressive diaphyseal dysplasia	0.022	0.978	0.000
Q78.2 Osteopetrosis	0.022	0.978	0.000
Q78.1 Polyostotic fibrous dysplasia	0.022	0.978	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.022	0.978	0.000
Q63.8 Other specified congenital malformations of kidney	0.022	0.978	0.000
Q63.3 Hyperplastic and giant kidney	0.022	0.978	0.000
Q76.1 Klippel-Feil syndrome	0.022	0.978	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.022	0.978	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.021	0.978	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations