TreeWAS – Variant ID: rs58691539

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N18.3 Chronic kidney disease, stage 3	0.000	0.971	0.029
N18 Chronic renal failure	0.000	0.972	0.028
N18.5 Chronic kidney disease, stage 5	0.000	0.975	0.025
N18.0 End-stage renal disease	0.000	0.975	0.025
N18.4 Chronic kidney disease, stage 4	0.000	0.976	0.024
N18.2 Chronic kidney disease, stage 2	0.000	0.978	0.022
N18.9 Chronic renal failure, unspecified	0.000	0.979	0.021
N18.1 Chronic kidney disease, stage 1	0.000	0.980	0.020
N18.8 Other chronic renal failure	0.000	0.981	0.019
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.018	0.982	0.000
K29.8 Duodenitis	0.000	0.985	0.015
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.989	0.010
T39.1 4-Aminophenol derivatives	0.000	0.990	0.010
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.990	0.010
G57.6 Lesion of plantar nerve	0.010	0.990	0.000
N13 Obstructive and reflux uropathy	0.009	0.991	0.000
N13.3 Other and unspecified hydronephrosis	0.009	0.991	0.000
T39.0 Salicylates	0.000	0.991	0.009
N13.5 Kinking and stricture of ureter without hydronephrosis	0.008	0.992	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.008	0.992	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.008	0.992	0.000
N13.6 Pyonephrosis	0.007	0.993	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.007	0.993	0.000
N13.4 Hydroureter	0.007	0.993	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.993	0.007
T39.4 Antirheumatics, not elsewhere classified	0.000	0.993	0.007
T39.2 Pyrazolone derivatives	0.000	0.993	0.007
N13.8 Other obstructive and reflux uropathy	0.007	0.993	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.007	0.993	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.007	0.993	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.994	0.006
S72.00 Fracture of neck of femur (closed)	0.000	0.994	0.006
N10-N16 Renal tubulo-interstitial diseases	0.005	0.995	0.000
G57 Mononeuropathies of lower limb	0.005	0.995	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.005	0.995	0.000
N11 Chronic tubulo-interstitial nephritis	0.004	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.995	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.004	0.996	0.000
N10 Acute tubulo-interstitial nephritis	0.004	0.996	0.000
H81.1 Benign paroxysmal vertigo	0.004	0.996	0.000
G57.5 Tarsal tunnel syndrome	0.004	0.996	0.000
R51 Headache	0.004	0.996	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.004	0.996	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.004	0.996	0.000
N15 Other renal tubulo-interstitial diseases	0.004	0.996	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.004	0.996	0.000
Y43.3 Other antineoplastic drugs	0.004	0.996	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.004	0.996	0.000
G57.4 Lesion of medial popliteal nerve	0.004	0.996	0.000
G57.3 Lesion of lateral popliteal nerve	0.004	0.996	0.000
G57.2 Lesion of femoral nerve	0.004	0.996	0.000
G57.0 Lesion of sciatic nerve	0.004	0.996	0.000
N17-N19 Renal failure	0.000	0.996	0.004
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
G57.1 Meralgia paraesthetica	0.004	0.996	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
S72.0 Fracture of neck of femur	0.000	0.996	0.004
G57.8 Other mononeuropathies of lower limb	0.004	0.996	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.003	0.996	0.000
N11.1 Chronic obstructive pyelonephritis	0.003	0.996	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.003	0.996	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
K90.0 Coeliac disease	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.003	0.997	0.000
N14.3 Nephropathy induced by heavy metals	0.003	0.997	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.003	0.997	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.003	0.997	0.000
N14.0 Analgesic nephropathy	0.003	0.997	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.003	0.997	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.003	0.997	0.000
N15.1 Renal and perinephric abscess	0.003	0.997	0.000
N15.0 Balkan nephropathy	0.003	0.997	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.003	0.997	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.003	0.997	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.003	0.997	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.003	0.997	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.003	0.997	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.003	0.997	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.997	0.000
I86.4 Gastric varices	0.003	0.997	0.000
T51.0 Ethanol	0.000	0.997	0.003
Y49.9 Psychotropic drug, unspecified	0.002	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.997	0.000
I86.1 Scrotal varices	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.997	0.000
Y56.9 Topical agent, unspecified	0.002	0.997	0.000
Y56.8 Other topical agents	0.002	0.997	0.000
Y56.7 Dental drugs, topically applied	0.002	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.997	0.000
Y56.2 Local astringents and local detergents	0.002	0.997	0.000
Y56.1 Antipruritics	0.002	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.997	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.997	0.003
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
H35.8 Other specified retinal disorders	0.000	0.997	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
I50.9 Heart failure, unspecified	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
K29.1 Other acute gastritis	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
W19.4 Street and highway	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
I86 Varicose veins of other sites	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z29 Need for other prophylactic measures	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
S80.0 Contusion of knee	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
X59.3 Sports and athletics area	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.002	0.998	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
R26.3 Immobility	0.000	0.998	0.002
X59 Exposure to unspecified factor	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.000	0.998	0.002
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
X58 Exposure to other specified factors	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.000	0.998	0.002
X58.9 Unspecified place	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
N17 Acute renal failure	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
U80.1 Methicillin resistant agent	0.002	0.998	0.000
S72 Fracture of femur	0.000	0.998	0.002
H35.6 Retinal haemorrhage	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Y85 Sequelae of transport accidents	0.002	0.998	0.000
Chapter XX External causes of morbidity and mortality	0.002	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
H33.5 Other retinal detachments	0.000	0.998	0.002
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998	0.000
I86.3 Vulval varices	0.002	0.998	0.000
I86.2 Pelvic varices	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
Z29.9 Prophylactic measure, unspecified	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
W50-W64 Exposure to animate mechanical forces	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
V80-V89 Other land transport accidents	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
Z29.0 Isolation	0.002	0.998	0.000
H35 Other retinal disorders	0.000	0.998	0.002
Y95 Nosocomial condition	0.002	0.998	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
G51.3 Clonic hemifacial spasm	0.002	0.998	0.000
R26.1 Paralytic gait	0.000	0.998	0.002
R26.0 Ataxic gait	0.000	0.998	0.002
X59.9 Unspecified place	0.002	0.998	0.000
X59.8 Other specified place	0.002	0.998	0.000
X59.0 Home	0.002	0.998	0.000
X59.7 Farm	0.002	0.998	0.000
X59.6 Industrial and construction area	0.002	0.998	0.000
X59.5 Trade and service area	0.002	0.998	0.000
X59.4 Street and highway	0.002	0.998	0.000
X59.2 School, other institution and public administrative area	0.002	0.998	0.000
X59.1 Residential institution	0.002	0.998	0.000
Y87.1 Sequelae of assault	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.000	0.998	0.002
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.002	0.998	0.000
W50.9 Unspecified place	0.002	0.998	0.000
X10-X19 Contact with heat and hot substances	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.998	0.000
Q51.4 Unicornate uterus	0.001	0.998	0.000
Q51.2 Other doubling of uterus	0.001	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
X58.8 Other specified place	0.001	0.998	0.000
X58.0 Home	0.001	0.998	0.000
X58.7 Farm	0.001	0.998	0.000
X58.6 Industrial and construction area	0.001	0.998	0.000
X58.5 Trade and service area	0.001	0.998	0.000
X58.4 Street and highway	0.001	0.998	0.000
X58.3 Sports and athletics area	0.001	0.998	0.000
X58.2 School, other institution and public administrative area	0.001	0.998	0.000
X58.1 Residential institution	0.001	0.998	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
J93.8 Other pneumothorax	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.998	0.000
N17.8 Other acute renal failure	0.000	0.998	0.001
N17.2 Acute renal failure with medullary necrosis	0.000	0.998	0.001
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.998	0.001
N17.0 Acute renal failure with tubular necrosis	0.000	0.998	0.001
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
X60-X84 Intentional self-harm	0.002	0.998	0.000
N95.2 Postmenopausal atrophic vaginitis	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.000	0.998	0.001
S72.8 Fractures of other parts of femur	0.000	0.998	0.001
S72.7 Multiple fractures of femur	0.000	0.998	0.001
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
G35 Multiple sclerosis	0.000	0.998	0.002
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
Y35-Y36 Legal intervention and operations of war	0.002	0.998	0.000
Y10-Y34 Event of undetermined intent	0.002	0.998	0.000
Y00-Y09 Assault	0.002	0.998	0.000
X85-X99 Assault	0.002	0.998	0.000
X30-X39 Exposure to forces of nature	0.002	0.998	0.000
X00-X09 Exposure to smoke, fire and flames	0.002	0.998	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.002	0.998	0.000
W75-W84 Other accidental threats to breathing	0.002	0.998	0.000
W65-W74 Accidental drowning and submersion	0.002	0.998	0.000
V98-V99 Other and unspecified transport accidents	0.002	0.998	0.000
V95-V97 Air and space transport accidents	0.002	0.998	0.000
V90-V94 Water transport accidents	0.002	0.998	0.000
V70-V79 Bus occupant injured in transport accident	0.002	0.998	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.002	0.998	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.002	0.998	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.002	0.998	0.000
V01-V09 Pedestrian injured in transport accident	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.000	0.998	0.001
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
X12 Contact with other hot fluids	0.001	0.998	0.000
Y89 Sequelae of other external causes	0.001	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
V40-V49 Car occupant injured in transport accident	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.001	0.998	0.000
Q54 Hypospadias	0.001	0.998	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.001	0.998	0.000
Y98 Lifestyle-related condition	0.001	0.998	0.000
Y97 Environmental-pollution-related condition	0.001	0.998	0.000
Y96 Work-related condition	0.001	0.998	0.000
X20-X29 Contact with venomous animals and plants	0.001	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
Q43.0 Meckel's diverticulum	0.001	0.998	0.000
Q43 Other congenital malformations of intestine	0.001	0.998	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.001	0.998	0.000
X50-X57 Overexertion, travel and privation	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.001	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.001	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.001	0.998	0.000
Q53 Undescended testicle	0.001	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.001	0.998	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.001	0.998	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.001	0.998	0.000
W59 Bitten or crushed by other reptiles	0.001	0.998	0.000
W58 Bitten or struck by crocodile or alligator	0.001	0.998	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.001	0.998	0.000
W56 Contact with marine animal	0.001	0.998	0.000
W55 Bitten or struck by other mammals	0.001	0.998	0.000
W54 Bitten or struck by dog	0.001	0.998	0.000
W53 Bitten by rat	0.001	0.998	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.001	0.998	0.000
W51 Striking against or bumped into by another person	0.001	0.998	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.998	0.001
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.001	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.001	0.998	0.000
Y87.2 Sequelae of events of undetermined intent	0.001	0.998	0.000
Y87.0 Sequelae of intentional self-harm	0.001	0.998	0.000
Q63 Other congenital malformations of kidney	0.001	0.998	0.000
Q82 Other congenital malformations of skin	0.001	0.998	0.000
V88 Nontraffic accident of specified type but victim's mode of transport unknown	0.001	0.998	0.000
V87 Traffic accident of specified type but victim's mode of transport unknown	0.001	0.998	0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident	0.001	0.998	0.000
V85 Occupant of special construction vehicle injured in transport accident	0.001	0.998	0.000
V84 Occupant of special vehicle mainly used in agriculture injured in transport accident	0.001	0.998	0.000
V83 Occupant of special vehicle mainly used on industrial premises injured in transport accident	0.001	0.998	0.000
V82 Occupant of streetcar injured in transport accident	0.001	0.998	0.000
V81 Occupant of railway train or railway vehicle injured in transport accident	0.001	0.998	0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident	0.001	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.001	0.998	0.000
X12.0 Home	0.001	0.998	0.000
X63.0 Home	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations