TreeWAS – Variant ID: rs59824868

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82 Fracture of lower leg, including ankle	0.024	0.976	0.000
S89.9 Unspecified injury of lower leg	0.024	0.976	0.000
M19.94 Arthrosis, unspecified (Hand)	0.023	0.977	0.000
S89 Other and unspecified injuries of lower leg	0.023	0.977	0.000
S82.3 Fracture of lower end of tibia	0.023	0.977	0.000
S80-S89 Injuries to the knee and lower leg	0.023	0.977	0.000
S82.0 Fracture of patella	0.023	0.977	0.000
S82.30 Fracture of lower end of tibia (closed)	0.023	0.977	0.000
S82.00 Fracture of patella (closed)	0.022	0.978	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.020	0.980	0.000
S82.4 Fracture of fibula alone	0.019	0.981	0.000
S89.8 Other specified injuries of lower leg	0.018	0.981	0.000
S82.5 Fracture of medial malleolus	0.018	0.982	0.000
S82.1 Fracture of upper end of tibia	0.018	0.982	0.000
S82.2 Fracture of shaft of tibia	0.018	0.982	0.000
S82.9 Fracture of lower leg, part unspecified	0.017	0.982	0.000
S82.7 Multiple fractures of lower leg	0.017	0.982	0.000
S83.2 Tear of meniscus, current	0.017	0.982	0.000
S89.7 Multiple injuries of lower leg	0.017	0.983	0.000
S89.1 Other specified injuries of lower leg	0.017	0.983	0.000
S89.0 Multiple injuries of lower leg	0.017	0.983	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.017	0.983	0.000
S86 Injury of muscle and tendon at lower leg level	0.017	0.983	0.000
S82.31 Fracture of lower end of tibia (open)	0.017	0.983	0.000
S81 Open wound of lower leg	0.017	0.983	0.000
S88 Traumatic amputation of lower leg	0.016	0.983	0.000
S87 Crushing injury of lower leg	0.016	0.983	0.000
S85 Injury of blood vessels at lower leg level	0.016	0.983	0.000
S84 Injury of nerves at lower leg level	0.016	0.983	0.000
S82.01 Fracture of patella (open)	0.016	0.983	0.000
S82.8 Fractures of other parts of lower leg	0.016	0.984	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.015	0.985	0.000
S82.6 Fracture of lateral malleolus	0.015	0.985	0.000
S82.40 Fracture of fibula alone (closed)	0.015	0.985	0.000
S83.7 Injury to multiple structures of knee	0.015	0.985	0.000
S83.3 Tear of articular cartilage of knee, current	0.015	0.985	0.000
S83.1 Dislocation of knee	0.015	0.985	0.000
S83.0 Dislocation of patella	0.015	0.985	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.014	0.986	0.000
S80 Superficial injury of lower leg	0.014	0.986	0.000
S82.50 Fracture of medial malleolus (closed)	0.014	0.986	0.000
S82.10 Fracture of upper end of tibia (closed)	0.014	0.986	0.000
S81.9 Open wound of lower leg, part unspecified	0.014	0.986	0.000
S82.21 Fracture of shaft of tibia (open)	0.014	0.986	0.000
S82.41 Fracture of fibula alone (open)	0.014	0.986	0.000
S82.51 Fracture of medial malleolus (open)	0.013	0.987	0.000
S82.11 Fracture of upper end of tibia (open)	0.013	0.987	0.000
S82.20 Fracture of shaft of tibia (closed)	0.013	0.987	0.000
S82.71 Multiple fractures of lower leg (open)	0.013	0.987	0.000
S82.70 Multiple fractures of lower leg (closed)	0.013	0.987	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.013	0.987	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.013	0.987	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.012	0.987	0.000
S82.81 Fractures of other parts of lower leg (open)	0.012	0.987	0.000
S86.0 Injury of Achilles tendon	0.012	0.988	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.012	0.988	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.012	0.988	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.012	0.988	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.012	0.988	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.012	0.988	0.000
S81.7 Multiple open wounds of lower leg	0.012	0.988	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.012	0.988	0.000
S84.8 Injury of other nerves at lower leg level	0.012	0.988	0.000
S84.7 Injury of multiple nerves at lower leg level	0.012	0.988	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.012	0.988	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.012	0.988	0.000
S84.0 Injury of tibial nerve at lower leg level	0.012	0.988	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.012	0.988	0.000
S85.8 Injury of other blood vessels at lower leg level	0.012	0.988	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.012	0.988	0.000
S85.5 Injury of popliteal vein	0.012	0.988	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.012	0.988	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.012	0.988	0.000
S85.2 Injury of peroneal artery	0.012	0.988	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.012	0.988	0.000
S85.0 Injury of popliteal artery	0.012	0.988	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.012	0.988	0.000
S87.0 Crushing injury of knee	0.012	0.988	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.012	0.988	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.012	0.988	0.000
S88.0 Traumatic amputation at knee level	0.012	0.988	0.000
S82.86 Maisonneuve's fracture	0.012	0.988	0.000
S80.8 Other superficial injuries of lower leg	0.012	0.988	0.000
S81.0 Open wound of knee	0.011	0.989	0.000
S82.61 Fracture of lateral malleolus (open)	0.011	0.989	0.000
S81.8 Open wound of other parts of lower leg	0.011	0.989	0.000
S80.7 Multiple superficial injuries of lower leg	0.010	0.989	0.000
E11 Non-insulin-dependent diabetes mellitus	0.010	0.990	0.000
E11.4 With neurological complications	0.010	0.990	0.000
E11.3 With ophthalmic complications	0.010	0.990	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.010	0.990	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.010	0.990	0.000
E11.9 Without complications	0.009	0.991	0.000
S86.00 Unspecified injury of Achilles tendon	0.009	0.991	0.000
S80.9 Superficial injury of lower leg, unspecified	0.009	0.991	0.000
S82.60 Fracture of lateral malleolus (closed)	0.009	0.991	0.000
S80.0 Contusion of knee	0.008	0.991	0.000
M19.9 Arthrosis, unspecified	0.009	0.991	0.000
E10-E14 Diabetes mellitus	0.008	0.992	0.000
E14 Unspecified diabetes mellitus	0.008	0.992	0.000
E11.8 With unspecified complications	0.008	0.992	0.000
E11.7 With multiple complications	0.008	0.992	0.000
E11.1 With ketoacidosis	0.008	0.992	0.000
E11.0 With coma	0.008	0.992	0.000
E11.5 With peripheral circulatory complications	0.008	0.992	0.000
E11.2 With renal complications	0.008	0.992	0.000
E14.3 With ophthalmic complications	0.008	0.992	0.000
M19 Other arthrosis	0.008	0.992	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.008	0.992	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.007	0.992	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.007	0.992	0.000
E10 Insulin-dependent diabetes mellitus	0.007	0.993	0.000
M19.0 Primary arthrosis of other joints	0.007	0.993	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
G56.0 Carpal tunnel syndrome	0.007	0.993	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.007	0.993	0.000
C90.0 Multiple myeloma	0.007	0.993	0.000
E10.5 With peripheral circulatory complications	0.007	0.993	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.007	0.993	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.006	0.994	0.000
E11.6 With other specified complications	0.006	0.994	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.006	0.994	0.000
E10.9 Without complications	0.006	0.994	0.000
M19.1 Posttraumatic arthrosis of other joints	0.006	0.994	0.000
I35.0 Aortic (valve) stenosis	0.006	0.994	0.000
C92 Myeloid leukaemia	0.006	0.994	0.000
C81 Hodgkin's disease	0.006	0.994	0.000
E12 Malnutrition-related diabetes mellitus	0.006	0.994	0.000
M19.2 Other secondary arthrosis	0.006	0.994	0.000
Z03.8 Observation for other suspected diseases and conditions	0.006	0.994	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.006	0.994	0.000
E10.3 With ophthalmic complications	0.006	0.994	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.006	0.994	0.000
E14.9 Without complications	0.006	0.994	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.006	0.994	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.006	0.994	0.000
E14.8 With unspecified complications	0.006	0.994	0.000
E14.7 With multiple complications	0.006	0.994	0.000
E14.6 With other specified complications	0.006	0.994	0.000
E14.5 With peripheral circulatory complications	0.006	0.994	0.000
E14.4 With neurological complications	0.006	0.994	0.000
E14.2 Withrenal complications	0.006	0.994	0.000
E14.1 With ketoacidosis	0.006	0.994	0.000
E14.0 With coma	0.006	0.994	0.000
C91 Lymphoid leukaemia	0.006	0.994	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.994	0.000
M19.8 Other specified arthrosis	0.006	0.994	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.006	0.994	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.005	0.994	0.000
E10.8 With unspecified complications	0.005	0.994	0.000
E10.7 With multiple complications	0.005	0.994	0.000
E10.6 With other specified complications	0.005	0.994	0.000
E10.2 With renal complications	0.005	0.994	0.000
E10.0 With coma	0.005	0.994	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.005	0.994	0.000
I35.1 Aortic (valve) insufficiency	0.005	0.995	0.000
C92.9 Myeloid leukaemia, unspecified	0.005	0.995	0.000
D62 Acute posthaemorrhagic anaemia	0.005	0.995	0.000
E10.1 With ketoacidosis	0.005	0.995	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.005	0.995	0.000
C83.1 Small cleaved cell (diffuse)	0.005	0.995	0.000
M19.98 Arthrosis, unspecified (Other)	0.005	0.995	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.005	0.995	0.000
M19.08 Primary arthrosis of other joints (Other)	0.005	0.995	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.005	0.995	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.005	0.995	0.000
C83.3 Large cell (diffuse)	0.005	0.995	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
C95 Leukaemia of unspecified cell type	0.005	0.995	0.000
C94 Other leukaemias of specified cell type	0.005	0.995	0.000
C93 Monocytic leukaemia	0.005	0.995	0.000
C88 Malignant immunoproliferative diseases	0.005	0.995	0.000
C86 Other specified types of T/NK-cell lymphoma	0.005	0.995	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.005	0.995	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.005	0.995	0.000
E13 Other specified diabetes mellitus	0.005	0.995	0.000
C92.1 Chronic myeloid leukaemia	0.005	0.995	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.005	0.995	0.000
C81.9 Hodgkin's disease, unspecified	0.005	0.995	0.000
C84.5 Other and unspecified T-cell lymphomas	0.005	0.995	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.005	0.995	0.000
C90.3 Solitary plasmacytoma	0.005	0.995	0.000
C90.1 Plasma cell leukaemia	0.005	0.995	0.000
I35 Nonrheumatic aortic valve disorders	0.005	0.995	0.000
C83.0 Small cell (diffuse)	0.005	0.995	0.000
C81.1 Nodular sclerosis	0.005	0.995	0.000
C83.7 Burkitt's tumour	0.005	0.995	0.000
C83.6 Undifferentiated (diffuse)	0.005	0.995	0.000
C83.5 Lymphoblastic (diffuse)	0.005	0.995	0.000
C83.4 Immunoblastic (diffuse)	0.005	0.995	0.000
C83.2 Mixed small and large cell (diffuse)	0.005	0.995	0.000
C82.0 Small cleaved cell, follicular	0.005	0.995	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.005	0.995	0.000
C91.1 Chronic lymphocytic leukaemia	0.005	0.995	0.000
C90.2 Plasmacytoma, extramedullary	0.005	0.995	0.000
D60-D64 Aplastic and other anaemias	0.005	0.995	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
M23.8 Other internal derangements of knee	0.005	0.995	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.995	0.005
M19.09 Primary arthrosis of other joints (Site unspecified)	0.005	0.995	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.005	0.995	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.005	0.995	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.005	0.995	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.005	0.995	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.005	0.995	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.005	0.995	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.005	0.995	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.005	0.995	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.005	0.995	0.000
C92.7 Other myeloid leukaemia	0.005	0.995	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.005	0.995	0.000
C92.5 Acute myelomonocytic leukaemia	0.005	0.995	0.000
C92.4 Acute promyelocytic leukaemia	0.005	0.995	0.000
C92.3 Myeloid sarcoma	0.005	0.995	0.000
C92.2 Subacute myeloid leukaemia	0.005	0.995	0.000
C81.7 Other Hodgkin's disease	0.004	0.995	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.004	0.995	0.000
C81.3 Lymphocytic depletion	0.004	0.995	0.000
C81.2 Mixed cellularity	0.004	0.995	0.000
C81.0 Lymphocytic predominance	0.004	0.995	0.000
E12.9 Without complications	0.004	0.995	0.000
E12.8 With unspecified complications	0.004	0.995	0.000
E12.7 With multiple complications	0.004	0.995	0.000
E12.6 With other specified complications	0.004	0.995	0.000
E12.5 With peripheral circulatory complications	0.004	0.995	0.000
E12.4 With neurological complications	0.004	0.995	0.000
E12.3 With ophthalmic complications	0.004	0.995	0.000
E12.2 With renal complications	0.004	0.995	0.000
E12.1 With ketoacidosis	0.004	0.995	0.000
E12.0 With coma	0.004	0.995	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.004	0.995	0.000
M19.28 Other secondary arthrosis (Other)	0.004	0.995	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.004	0.995	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.004	0.995	0.000
M19.24 Other secondary arthrosis (Hand)	0.004	0.995	0.000
M19.23 Other secondary arthrosis (Forearm)	0.004	0.995	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.004	0.995	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.004	0.995	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.004	0.995	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.005	0.995	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.004	0.995	0.000
C82.6 Cutaneous follicle centre lymphoma	0.004	0.995	0.000
C82.5 Diffuse follicle centre lymphoma	0.004	0.995	0.000
C82.4 Follicular lymphoma grade IIIb	0.004	0.995	0.000
C82.3 Follicular lymphoma grade IIIa	0.004	0.995	0.000
C82.2 Large cell, follicular	0.004	0.995	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.004	0.995	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.004	0.995	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.004	0.995	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.004	0.995	0.000
C84.4 Peripheral T-cell lymphoma	0.004	0.995	0.000
C84.3 Lymphoepithelioid lymphoma	0.004	0.995	0.000
C84.2 T-zone lymphoma	0.004	0.995	0.000
C84.1 Sezary's diease	0.004	0.995	0.000
C84.0 Mycosis fungoides	0.004	0.995	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.005	0.995	0.000
M48.06 Spinal stenosis (Lumbar region)	0.005	0.995	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.004	0.995	0.000
C85.0 Lymphosarcoma	0.004	0.995	0.000
C91.9 Lymphoid leukaemia, unspecified	0.004	0.996	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.004	0.996	0.000
C91.7 Other lymphoid leukaemia	0.004	0.996	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.004	0.996	0.000
C91.5 Adult T-cell leukaemia	0.004	0.996	0.000
C91.4 Hairy-cell leukaemia	0.004	0.996	0.000
C91.3 Prolymphocytic leukaemia	0.004	0.996	0.000
C91.2 Subacute lymphocytic leukaemia	0.004	0.996	0.000
C91.0 Acute lymphoblastic leukaemia	0.004	0.996	0.000
M24 Other specific joint derangements	0.004	0.996	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.004	0.996	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.004	0.996	0.000
M19.88 Other specified arthrosis (Other)	0.004	0.996	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.004	0.996	0.000
M19.86 Other specified arthrosis (Lower leg)	0.004	0.996	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.004	0.996	0.000
M19.84 Other specified arthrosis (Hand)	0.004	0.996	0.000
M19.83 Other specified arthrosis (Forearm)	0.004	0.996	0.000
M19.82 Other specified arthrosis (Upper arm)	0.004	0.996	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.004	0.996	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.004	0.996	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.004	0.996	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.004	0.996	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.004	0.996	0.000
M23 Internal derangement of knee	0.004	0.996	0.000
M86-M90 Other osteopathies	0.004	0.996	0.000
M65-M68 Disorders of synovium and tendon	0.004	0.996	0.000
I35.9 Aortic valve disorder, unspecified	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
D64 Other anaemias	0.004	0.996	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.004	0.996	0.000
D63.0 Anaemia in neoplastic disease	0.004	0.996	0.000
M67 Other disorders of synovium and tendon	0.004	0.996	0.000
M15-M19 Arthrosis	0.004	0.996	0.000
I78.1 Naevus, nonneoplastic	0.000	0.996	0.004
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.004	0.996	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.004	0.996	0.000
C86.4 Blastic NK-cell lymphoma	0.004	0.996	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.004	0.996	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.004	0.996	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.004	0.996	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.004	0.996	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.004	0.996	0.000
C88.7 Other malignant immunoproliferative diseases	0.004	0.996	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.004	0.996	0.000
C88.3 Immunoproliferative small intestinal disease	0.004	0.996	0.000
C88.2 Gamma heavy chain disease	0.004	0.996	0.000
C88.1 Alpha heavy chain disease	0.004	0.996	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.004	0.996	0.000
C93.9 Monocytic leukaemia, unspecified	0.004	0.996	0.000
C93.7 Other monocytic leukaemia	0.004	0.996	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.004	0.996	0.000
C93.2 Subacute monocytic leukaemia	0.004	0.996	0.000
C93.1 Chronic monocytic leukaemia	0.004	0.996	0.000
C93.0 Acute monocytic leukaemia	0.004	0.996	0.000
C94.7 Other specified leukaemias	0.004	0.996	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.004	0.996	0.000
C94.5 Acute myelofibrosis	0.004	0.996	0.000
C94.4 Acute panmyelosis	0.004	0.996	0.000
C94.3 Mast cell leukaemia	0.004	0.996	0.000
C94.2 Acute megakaryoblastic leukaemia	0.004	0.996	0.000
C94.1 Chronic erythraemia	0.004	0.996	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.004	0.996	0.000
C95.9 Leukaemia, unspecified	0.004	0.996	0.000
C95.7 Other leukaemia of unspecified cell type	0.004	0.996	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.004	0.996	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.004	0.996	0.000
C95.0 Acute leukaemia of unspecified cell type	0.004	0.996	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
C96.8 Histiocytic sarcoma	0.004	0.996	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.004	0.996	0.000
C96.3 True histiocytic lymphoma	0.004	0.996	0.000
C96.2 Malignant mast cell tumour	0.004	0.996	0.000
C96.1 Malignant histiocytosis	0.004	0.996	0.000
C96.0 Letterer-Siwe disease	0.004	0.996	0.000
C92.0 Acute myeloid leukaemia	0.004	0.996	0.000
E10.4 With neurological complications	0.004	0.996	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.004	0.996	0.000
E13.8 With unspecified complications	0.004	0.996	0.000
E13.7 With multiple complications	0.004	0.996	0.000
E13.6 With other specified complications	0.004	0.996	0.000
E13.5 With peripheral circulatory complications	0.004	0.996	0.000
E13.4 With neurological complications	0.004	0.996	0.000
E13.3 With ophthalmic complications	0.004	0.996	0.000
E13.2 With renal complications	0.004	0.996	0.000
E13.1 With ketoacidosis	0.004	0.996	0.000
E13.0 With coma	0.004	0.996	0.000
M87 Osteonecrosis	0.004	0.996	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.004	0.996	0.000
M24.0 Loose body in joint	0.004	0.996	0.000
M18 Arthrosis of first carpometacarpal joint	0.004	0.996	0.000
M86 Osteomyelitis	0.004	0.996	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
M23.4 Loose body in knee	0.004	0.996	0.000
M48.0 Spinal stenosis	0.004	0.996	0.000
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.004	0.996	0.000
M23.1 Discoid meniscus (congenital)	0.004	0.996	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.004	0.996	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
M66 Spontaneous rupture of synovium and tendon	0.004	0.996	0.000
M65 Synovitis and tenosynovitis	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.004	0.996	0.000
M89 Other disorders of bone	0.004	0.996	0.000
M45-M49 Spondylopathies	0.004	0.996	0.000
D64.9 Anaemia, unspecified	0.004	0.996	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.004	0.996	0.000
G56 Mononeuropathies of upper limb	0.004	0.996	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.004	0.996	0.000
M90 Osteopathies in diseases classified elsewhere	0.004	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.004	0.996	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.004	0.996	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.004	0.996	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
M23.9 Internal derangement of knee, unspecified	0.004	0.996	0.000
M20-M25 Other joint disorders	0.004	0.996	0.000
G59.0 Diabetic mononeuropathy	0.004	0.996	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.004	0.996	0.000
M85.0 Fibrous dysplasia (monostotic)	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.004	0.996	0.000
M67.4 Ganglion	0.004	0.996	0.000
M87.9 Osteonecrosis, unspecified	0.004	0.996	0.000
M48 Other spondylopathies	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.004	0.996	0.000
M23.49 Loose body in knee-Unspec lig/men	0.004	0.996	0.000
M47.9 Spondylosis, unspecified	0.004	0.996	0.000
G44.2 Tension-type headache	0.004	0.996	0.000
G62 Other polyneuropathies	0.004	0.996	0.000
G62.8 Other specified polyneuropathies	0.004	0.996	0.000
M86.9 Osteomyelitis, unspecified	0.003	0.996	0.000
M24.5 Contracture of joint	0.003	0.996	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.003	0.996	0.000
M47 Spondylosis	0.004	0.996	0.000
M24.2 Disorder of ligament	0.003	0.996	0.000
M66.0 Rupture of popliteal cyst	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
M24.7 Protrusio acetabuli	0.003	0.997	0.000
M24.6 Ankylosis of joint	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
M23.0 Cystic meniscus	0.003	0.997	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
M67.1 Other contracture of tendon (sheath)	0.003	0.997	0.000
M87.8 Other osteonecrosis	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M86.6 Other chronic osteomyelitis	0.003	0.997	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.003	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.003	0.997	0.000
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
I35.8 Other aortic valve disorders	0.003	0.997	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M15 Polyarthrosis	0.003	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
M90.7 Fracture of bone in neoplastic disease	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.003	0.997	0.000
D64.8 Other specified anaemias	0.003	0.997	0.000
D64.4 Congenital dyserythropoietic anaemia	0.003	0.997	0.000
D64.3 Other sideroblastic anaemias	0.003	0.997	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.003	0.997	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.003	0.997	0.000
D64.0 Hereditary sideroblastic anaemia	0.003	0.997	0.000
M47.1 Other spondylosis with myelopathy	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.003	0.997	0.000
D55-D59 Haemolytic anaemias	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.003	0.997	0.000
M67.3 Transient synovitis	0.003	0.997	0.000
M67.0 Short Achilles tendon (acquired)	0.003	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.003	0.997	0.000
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
M67.43 Ganglion, wrist	0.003	0.997	0.000
E13.9 Without complications	0.003	0.997	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.003	0.997	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
D61 Other aplastic anaemias	0.003	0.997	0.000
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M87.3 Other secondary osteonecrosis	0.003	0.997	0.000
M87.1 Osteonecrosis due to drugs	0.003	0.997	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.003	0.997	0.000
G54 Nerve root and plexus disorders	0.003	0.997	0.000
M67.8 Other specified disorders of synovium and tendon	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.997	0.000
M24.08 Loose body in joint (Other)	0.003	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.04 Loose body in joint (Hand)	0.003	0.997	0.000
M24.03 Loose body in joint (Forearm)	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.997	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.997	0.003
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.003	0.997	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.003	0.997	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.003	0.997	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.003	0.997	0.000
M86.8 Other osteomyelitis	0.003	0.997	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.997	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.003	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.997	0.000
M86.2 Subacute osteomyelitis	0.003	0.997	0.000
M86.1 Other acute osteomyelitis	0.003	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.003	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
G54.0 Brachial plexus disorders	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
M23.47 Loose body in knee-Capsular lig	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations