TreeWAS – Variant ID: rs6056869

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K29.5 Chronic gastritis, unspecified	0.124	0.876	0.000
C02.1 Border of tongue	0.053	0.947	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.052	0.948	0.000
C02.9 Tongue, unspecified	0.049	0.951	0.000
C77.3 Axillary and upper limb lymph nodes	0.046	0.954	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.045	0.955	0.000
C10 Malignant neoplasm of oropharynx	0.041	0.959	0.000
C02.4 Lingual tonsil	0.039	0.961	0.000
C13 Malignant neoplasm of hypopharynx	0.038	0.962	0.000
C05 Malignant neoplasm of palate	0.038	0.962	0.000
C10.9 Oropharynx, unspecified	0.038	0.962	0.000
J32.0 Chronic maxillary sinusitis	0.038	0.962	0.000
C02.8 Overlapping lesion of tongue	0.037	0.962	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.037	0.962	0.000
C02.0 Dorsal surface of tongue	0.037	0.962	0.000
C12 Malignant neoplasm of pyriform sinus	0.037	0.963	0.000
C02.2 Ventral surface of tongue	0.037	0.963	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.037	0.963	0.000
C01 Malignant neoplasm of base of tongue	0.036	0.964	0.000
C09 Malignant neoplasm of tonsil	0.035	0.965	0.000
C00 Malignant neoplasm of lip	0.033	0.967	0.000
C05.1 Soft palate	0.033	0.967	0.000
C13.9 Hypopharynx, unspecified	0.032	0.968	0.000
C11 Malignant neoplasm of nasopharynx	0.032	0.968	0.000
C04 Malignant neoplasm of floor of mouth	0.031	0.969	0.000
C06.2 Retromolar area	0.030	0.969	0.000
C03 Malignant neoplasm of gum	0.030	0.970	0.000
C10.8 Overlapping lesion of oropharynx	0.029	0.970	0.000
C10.4 Branchial cleft	0.029	0.970	0.000
C10.3 Posterior wall of oropharynx	0.029	0.970	0.000
C10.2 Lateral wall of oropharynx	0.029	0.970	0.000
C10.1 Anterior surface of epiglottis	0.029	0.970	0.000
C10.0 Vallecula	0.029	0.970	0.000
C13.0 Postcricoid region	0.029	0.971	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.029	0.971	0.000
C07 Malignant neoplasm of parotid gland	0.029	0.971	0.000
C05.0 Hard palate	0.028	0.971	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.028	0.972	0.000
C13.8 Overlapping lesion of hypopharynx	0.028	0.972	0.000
C13.2 Posterior wall of hypopharynx	0.028	0.972	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.028	0.972	0.000
C05.9 Palate, unspecified	0.028	0.972	0.000
C05.8 Overlapping lesion of palate	0.028	0.972	0.000
C05.2 Uvula	0.028	0.972	0.000
C09.9 Tonsil, unspecified	0.028	0.972	0.000
C06.0 Cheek mucosa	0.027	0.973	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.026	0.973	0.000
C06.1 Vestibule of mouth	0.026	0.973	0.000
C06.9 Mouth, unspecified	0.026	0.974	0.000
C00.0 External upper lip	0.025	0.974	0.000
C09.8 Overlapping lesion of tonsil	0.025	0.975	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.025	0.975	0.000
C09.0 Tonsillar fossa	0.025	0.975	0.000
C00.8 Overlapping lesion of lip	0.024	0.976	0.000
C00.6 Commissure of lip	0.024	0.976	0.000
C00.5 Lip, unspecified, inner aspect	0.024	0.976	0.000
C00.4 Lower lip, inner aspect	0.024	0.976	0.000
C00.3 Upper lip, inner aspect	0.024	0.976	0.000
C00.2 External lip, unspecified	0.024	0.976	0.000
C04.0 Anterior floor of mouth	0.024	0.976	0.000
C00.9 Lip, unspecified	0.023	0.977	0.000
C00.1 External lower lip	0.023	0.977	0.000
C11.8 Overlapping lesion of nasopharynx	0.023	0.977	0.000
C11.3 Anterior wall of nasopharynx	0.023	0.977	0.000
C11.2 Lateral wall of nasopharynx	0.023	0.977	0.000
C11.1 Posterior wall of nasopharynx	0.023	0.977	0.000
C11.0 Superior wall of nasopharynx	0.023	0.977	0.000
C04.8 Overlapping lesion of floor of mouth	0.022	0.978	0.000
C04.1 Lateral floor of mouth	0.022	0.978	0.000
C11.9 Nasopharynx, unspecified	0.022	0.978	0.000
C03.9 Gum, unspecified	0.021	0.978	0.000
C03.0 Upper gum	0.021	0.978	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.021	0.979	0.000
C14.2 Waldeyer's ring	0.021	0.979	0.000
C08.8 Overlapping lesion of major salivary glands	0.020	0.980	0.000
C08.1 Sublingual gland	0.020	0.980	0.000
C08.0 Submandibular gland	0.019	0.981	0.000
C04.9 Floor of mouth, unspecified	0.019	0.981	0.000
C03.1 Lower gum	0.018	0.981	0.000
C08.9 Major salivary gland, unspecified	0.017	0.982	0.000
C14.0 Pharynx, unspecified	0.017	0.982	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.018	0.982	0.000
C77.4 Inguinal and lower limb lymph nodes	0.017	0.983	0.000
C77.1 Intrathoracic lymph nodes	0.016	0.984	0.000
M22.2 Patellofemoral disorders	0.013	0.987	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.013	0.987	0.000
H43.1 Vitreous haemorrhage	0.000	0.987	0.012
M22.8 Other disorders of patella	0.012	0.988	0.000
N60.8 Other benign mammary dysplasias	0.000	0.988	0.012
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.989	0.011
M22 Disorders of patella	0.011	0.989	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.989	0.011
C77.5 Intrapelvic lymph nodes	0.011	0.989	0.000
N60.3 Fibrosclerosis of breast	0.000	0.989	0.011
C77.8 Lymph nodes of multiple regions	0.011	0.989	0.000
C92.0 Acute myeloid leukaemia	0.011	0.989	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
I67.9 Cerebrovascular disease, unspecified	0.010	0.990	0.000
M22.4 Chondromalacia patellae	0.010	0.990	0.000
I67.2 Cerebral atherosclerosis	0.010	0.990	0.000
N60 Benign mammary dysplasia	0.000	0.991	0.009
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.991	0.009
N60.1 Diffuse cystic mastopathy	0.000	0.991	0.009
C77.0 Lymph nodes of head, face and neck	0.009	0.991	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.991	0.009
M22.0 Recurrent dislocation of patella	0.008	0.991	0.000
M22.1 Recurrent subluxation of patella	0.008	0.992	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
I67 Other cerebrovascular diseases	0.008	0.992	0.000
M22.9 Disorder of patella, unspecified	0.007	0.992	0.000
M22.3 Other derangements of patella	0.007	0.993	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.993	0.007
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
L90.0 Lichen sclerosus et atrophicus	0.007	0.993	0.000
Q63.0 Accessory kidney	0.007	0.993	0.000
C77.9 Lymph node, unspecified	0.007	0.993	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.007	0.993	0.000
C77.2 Intra-abdominal lymph nodes	0.007	0.993	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.006
M22.10 Recurrent subluxation of patella, unspecified knee	0.006	0.994	0.000
H02.1 Ectropion of eyelid	0.006	0.994	0.000
C92 Myeloid leukaemia	0.006	0.994	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.006	0.994	0.000
I67.5 Moyamoya disease	0.006	0.994	0.000
I67.4 Hypertensive encephalopathy	0.006	0.994	0.000
I67.3 Progressive vascular leukoencephalopathy	0.006	0.994	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.006	0.994	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.006	0.994	0.000
N60.2 Fibroadenosis of breast	0.000	0.994	0.006
C92.4 Acute promyelocytic leukaemia	0.005	0.994	0.000
Q63 Other congenital malformations of kidney	0.005	0.995	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.005	0.995	0.000
C92.9 Myeloid leukaemia, unspecified	0.005	0.995	0.000
C92.7 Other myeloid leukaemia	0.005	0.995	0.000
R94.5 Abnormal results of liver function studies	0.000	0.995	0.005
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.995	0.005
N60.0 Solitary cyst of breast	0.000	0.995	0.005
M06.0 Seronegative rheumatoid arthritis	0.005	0.995	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.005	0.995	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.005	0.995	0.000
C92.5 Acute myelomonocytic leukaemia	0.005	0.995	0.000
C92.3 Myeloid sarcoma	0.005	0.995	0.000
C92.2 Subacute myeloid leukaemia	0.005	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
H43.3 Other vitreous opacities	0.004	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
R45.1 Restlessness and agitation	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
I67.1 Cerebral aneurysm, nonruptured	0.004	0.996	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.004	0.996	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.004	0.996	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.004	0.996	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.004	0.996	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.004	0.996	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.004	0.996	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.004	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.004	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.004	0.996	0.000
Q07 Other congenital malformations of nervous system	0.004	0.996	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.004	0.996	0.000
Q07.0 Arnold-Chiari syndrome	0.004	0.996	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.004	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.004	0.996	0.000
I67.8 Other specified cerebrovascular diseases	0.004	0.996	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.996	0.004
Q14.1 Congenital malformation of retina	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
Q04 Other congenital malformations of brain	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.004	0.996	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.004	0.996	0.000
Z51.1 Chemotherapy session for neoplasm	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q03 Congenital hydrocephalus	0.004	0.996	0.000
Q63.2 Ectopic kidney	0.004	0.996	0.000
Q90.9 Down's syndrome, unspecified	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.004	0.996	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.004	0.996	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.004	0.996	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.004	0.996	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
E66.8 Other obesity	0.000	0.996	0.004
Z90.3 Acquired absence of part of stomach	0.004	0.996	0.000
C92.1 Chronic myeloid leukaemia	0.003	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.996	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.000	0.997	0.003
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.997	0.003
O95 Obstetric death of unspecified cause	0.000	0.997	0.003
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
D27 Benign neoplasm of ovary	0.000	0.997	0.003
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.000	0.997	0.003
Q07.9 Congenital malformation of nervous system, unspecified	0.003	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.997	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q14.3 Congenital malformation of choroid	0.003	0.997	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.997	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
C18.2 Ascending colon	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
Q04.9 Congenital malformation of brain, unspecified	0.003	0.997	0.000
Q04.5 Megalencephaly	0.003	0.997	0.000
Q04.4 Septo-optic dysplasia	0.003	0.997	0.000
Q04.3 Other reduction deformities of brain	0.003	0.997	0.000
Q04.2 Holoprosencephaly	0.003	0.997	0.000
Q04.1 Arhinencephaly	0.003	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.997	0.003
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.997	0.000
Q90.2 Trisomy 21, translocation	0.003	0.997	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
W25.9 Unspecified place	0.000	0.997	0.003
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.003	0.997	0.000
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
Q10.0 Congenital ptosis	0.003	0.997	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
Q15.0 Congenital glaucoma	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q17.5 Prominent ear	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
C78.2 Secondary malignant neoplasm of pleura	0.003	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
O96.9 Death from unspecified obstetric cause	0.000	0.997	0.003
O96.1 Death from indirect obstetric cause	0.000	0.997	0.003
O96.0 Death from direct obstetric cause	0.000	0.997	0.003
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.997	0.003
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.997	0.003
O97.0 Death from sequelae of direct obstetric cause	0.000	0.997	0.003
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.000	0.997	0.003
N05.9 Unspecified	0.003	0.997	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.003	0.997	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q10.7 Congenital malformation of orbit	0.003	0.997	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.003	0.997	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.003	0.997	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.003	0.997	0.000
Q10.3 Other congenital malformations of eyelid	0.003	0.997	0.000
Q10.2 Congenital entropion	0.003	0.997	0.000
Q10.1 Congenital ectropion	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q15.9 Congenital malformation of eye, unspecified	0.003	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.003	0.997	0.000
C95.9 Leukaemia, unspecified	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.997	0.003
Q17.9 Congenital malformation of ear, unspecified	0.003	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.003	0.997	0.000
Q17.4 Misplaced ear	0.003	0.997	0.000
Q17.3 Other misshapen ear	0.003	0.997	0.000
Q17.2 Microtia	0.003	0.997	0.000
Q17.1 Macrotia	0.003	0.997	0.000
Q17.0 Accessory auricle	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.997	0.000
Q33 Congenital malformations of lung	0.002	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.997	0.000
Q30 Congenital malformations of nose	0.002	0.997	0.000
K55.2 Angiodysplasia of colon	0.003	0.997	0.000
Q00.2 Iniencephaly	0.002	0.997	0.000
Q00.1 Craniorachischisis	0.002	0.997	0.000
Q00.0 Anencephaly	0.002	0.997	0.000
Q01.9 Encephalocele, unspecified	0.002	0.997	0.000
Q01.8 Encephalocele of other sites	0.002	0.997	0.000
Q01.2 Occipital encephalocele	0.002	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.997	0.000
Q01.0 Frontal encephalocele	0.002	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.997	0.000
Q06.4 Hydromyelia	0.002	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.997	0.000
Q06.2 Diastematomyelia	0.002	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.997	0.000
Q06.0 Amyelia	0.002	0.997	0.000
C76.2 Abdomen	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.003	0.997	0.000
N18.5 Chronic kidney disease, stage 5	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.002	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
C78.7 Secondary malignant neoplasm of liver	0.003	0.997	0.000
Q11.3 Macrophthalmos	0.002	0.997	0.000
Q11.2 Microphthalmos	0.002	0.997	0.000
Q11.1 Other anophthalmos	0.002	0.997	0.000
Q11.0 Cystic eyeball	0.002	0.997	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.002	0.997	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q13.5 Blue sclera	0.002	0.997	0.000
Q13.4 Other congenital corneal malformations	0.002	0.997	0.000
Q13.3 Congenital corneal opacity	0.002	0.997	0.000
Q13.2 Other congenital malformations of iris	0.002	0.997	0.000
Q13.1 Absence of iris	0.002	0.997	0.000
Q13.0 Coloboma of iris	0.002	0.997	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.997	0.000
Q16.5 Congenital malformation of inner ear	0.002	0.997	0.000
Q16.4 Other congenital malformations of middle ear	0.002	0.997	0.000
Q16.3 Congenital malformation of ear ossicles	0.002	0.997	0.000
Q16.2 Absence of eustachian tube	0.002	0.997	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.002	0.997	0.000
Q16.0 Congenital absence of (ear) auricle	0.002	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.997	0.003
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.997	0.000
Q64.4 Malformation of urachus	0.002	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.997	0.000
Q64.0 Epispadias	0.002	0.997	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.002	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q05 Spina bifida	0.002	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.997	0.000
Q43.7 Persistent cloaca	0.002	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.997	0.000
Q43.5 Ectopic anus	0.002	0.997	0.000
Q43.4 Duplication of intestine	0.002	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.997	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.003	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.003	0.997	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
Q39.4 Oesophageal web	0.002	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.997	0.000
Q43.0 Meckel's diverticulum	0.002	0.997	0.000
C91.0 Acute lymphoblastic leukaemia	0.003	0.997	0.000
Q54.8 Other hypospadias	0.002	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.997	0.000
Q38.2 Macroglossia	0.002	0.997	0.000
Q38.1 Ankyloglossia	0.002	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.997	0.000
Q54.4 Congenital chordee	0.002	0.997	0.000
Q54.3 Hypospadias, perineal	0.002	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.002	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.997	0.000
Q78 Other osteochondrodysplasias	0.002	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.998	0.000
Q91.6 Trisomy 13, translocation	0.002	0.998	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.998	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.998	0.000
Q91.2 Trisomy 18, translocation	0.002	0.998	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.998	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.998	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.998	0.000
Q92.7 Triploidy and polyploidy	0.002	0.998	0.000
Q92.6 Extra marker chromosomes	0.002	0.998	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.998	0.000
Q92.4 Duplications seen only at prometaphase	0.002	0.998	0.000
Q92.3 Minor partial trisomy	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations