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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61743495
log Bayes Factor = 0.386817
Chromosome 16   position 1,484,455  (GRCh37) Explore rs61743495 on Ensembl!
Variant rs61743495 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.404 0.596
E11 Non-insulin-dependent diabetes mellitus
0.000 0.509 0.491
E11.5 With peripheral circulatory complications
0.000 0.572 0.428
E11.4 With neurological complications
0.000 0.588 0.412
E11.2 With renal complications
0.000 0.613 0.387
E11.1 With ketoacidosis
0.000 0.624 0.376
E11.8 With unspecified complications
0.000 0.648 0.352
E11.7 With multiple complications
0.000 0.648 0.352
E11.0 With coma
0.000 0.648 0.352
E11.6 With other specified complications
0.000 0.684 0.316
E10-E14 Diabetes mellitus
0.000 0.689 0.311
E14 Unspecified diabetes mellitus
0.000 0.710 0.290
E14.9 Without complications
0.000 0.728 0.272
E12 Malnutrition-related diabetes mellitus
0.000 0.777 0.223
E14.3 With ophthalmic complications
0.000 0.779 0.221
E14.8 With unspecified complications
0.000 0.792 0.208
E14.7 With multiple complications
0.000 0.792 0.208
E14.6 With other specified complications
0.000 0.792 0.208
E14.5 With peripheral circulatory complications
0.000 0.792 0.208
E14.4 With neurological complications
0.000 0.792 0.208
E14.2 Withrenal complications
0.000 0.792 0.208
E14.1 With ketoacidosis
0.000 0.792 0.208
E14.0 With coma
0.000 0.792 0.208
E13 Other specified diabetes mellitus
0.000 0.800 0.199
E11.3 With ophthalmic complications
0.000 0.802 0.198
E10 Insulin-dependent diabetes mellitus
0.000 0.812 0.188
E12.9 Without complications
0.000 0.840 0.160
E12.8 With unspecified complications
0.000 0.840 0.160
E12.7 With multiple complications
0.000 0.840 0.160
E12.6 With other specified complications
0.000 0.840 0.160
E12.5 With peripheral circulatory complications
0.000 0.840 0.160
E12.4 With neurological complications
0.000 0.840 0.160
E12.3 With ophthalmic complications
0.000 0.840 0.160
E12.2 With renal complications
0.000 0.840 0.160
E12.1 With ketoacidosis
0.000 0.840 0.160
E12.0 With coma
0.000 0.840 0.160
E10.1 With ketoacidosis
0.000 0.848 0.152
E13.8 With unspecified complications
0.000 0.857 0.143
E13.7 With multiple complications
0.000 0.857 0.143
E13.6 With other specified complications
0.000 0.857 0.143
E13.5 With peripheral circulatory complications
0.000 0.857 0.143
E13.4 With neurological complications
0.000 0.857 0.143
E13.3 With ophthalmic complications
0.000 0.857 0.143
E13.2 With renal complications
0.000 0.857 0.143
E13.1 With ketoacidosis
0.000 0.857 0.143
E13.0 With coma
0.000 0.857 0.143
E10.3 With ophthalmic complications
0.000 0.859 0.140
E10.8 With unspecified complications
0.000 0.865 0.135
E10.7 With multiple complications
0.000 0.865 0.135
E10.6 With other specified complications
0.000 0.865 0.135
E10.5 With peripheral circulatory complications
0.000 0.865 0.135
E10.2 With renal complications
0.000 0.865 0.135
E10.0 With coma
0.000 0.865 0.135
E10.4 With neurological complications
0.000 0.877 0.123
E13.9 Without complications
0.000 0.880 0.120
E10.9 Without complications
0.000 0.932 0.068
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.982 0.018
H02.4 Ptosis of eyelid
0.017 0.983 0.000
E50-E64 Other nutritional deficiencies
0.000 0.985 0.014
E40-E46 Malnutrition
0.000 0.986 0.014
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.987 0.013
T43.2 Other and unspecified antidepressants
0.000 0.987 0.013
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.987 0.013
E55 Vitamin D deficiency
0.000 0.988 0.012
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.988 0.011
E61 Deficiency of other nutrient elements
0.000 0.989 0.011
C44.5 Skin of trunk
0.000 0.989 0.011
E55.9 Vitamin D deficiency, unspecified
0.000 0.989 0.011
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.989 0.011
E63 Other nutritional deficiencies
0.000 0.989 0.011
E56 Other vitamin deficiencies
0.000 0.989 0.011
E51 Thiamine deficiency
0.000 0.989 0.011
E50 Vitamin A deficiency
0.000 0.989 0.011
E60 Dietary zinc deficiency
0.000 0.989 0.011
E59 Dietary selenium deficiency
0.000 0.989 0.011
E58 Dietary calcium deficiency
0.000 0.989 0.011
E54 Ascorbic acid deficiency
0.000 0.989 0.011
E52 Niacin deficiency [pellagra]
0.000 0.989 0.011
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.989 0.011
E46 Unspecified protein-energy malnutrition
0.000 0.989 0.010
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.990 0.010
R00.0 Tachycardia, unspecified
0.010 0.990 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.990 0.010
E45 Retarded development following protein-energy malnutrition
0.000 0.990 0.010
E43 Unspecified severe protein-energy malnutrition
0.000 0.990 0.010
E42 Marasmic kwashiorkor
0.000 0.990 0.010
E41 Nutritional marasmus
0.000 0.990 0.010
E40 Kwashiorkor
0.000 0.990 0.010
T39.1 4-Aminophenol derivatives
0.000 0.990 0.010
E20-E35 Disorders of other endocrine glands
0.000 0.990 0.010
E65-E68 Obesity and other hyperalimentation
0.000 0.990 0.010
E15 Nondiabetic hypoglycaemic coma
0.000 0.990 0.010
E16 Other disorders of pancreatic internal secretion
0.000 0.990 0.010
E53 Deficiency of other B group vitamins
0.000 0.990 0.009
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.991 0.009
T43.9 Psychotropic drug, unspecified
0.000 0.991 0.009
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.991 0.009
T43.6 Psychostimulants with abuse potential
0.000 0.991 0.009
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.991 0.009
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.991 0.009
E55.0 Rickets, active
0.000 0.991 0.009
T39.0 Salicylates
0.000 0.991 0.009
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.991 0.009
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.991 0.009
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.991 0.009
E00-E07 Disorders of thyroid gland
0.000 0.991 0.009
E61.1 Iron deficiency
0.000 0.991 0.008
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.992 0.008
E61.9 Deficiency of nutrient element, unspecified
0.000 0.992 0.008
E61.8 Deficiency of other specified nutrient elements
0.000 0.992 0.008
E61.7 Deficiency of multiple nutrient elements
0.000 0.992 0.008
E61.6 Vanadium deficiency
0.000 0.992 0.008
E61.5 Molybdenum deficiency
0.000 0.992 0.008
E61.4 Chromium deficiency
0.000 0.992 0.008
E61.3 Manganese deficiency
0.000 0.992 0.008
E61.2 Magnesium deficiency
0.000 0.992 0.008
E61.0 Copper deficiency
0.000 0.992 0.008
E23 Hypofunction and other disorders of pituitary gland
0.000 0.992 0.008
T40.2 Other opioids
0.000 0.992 0.008
I51.7 Cardiomegaly
0.008 0.992 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.992 0.008
E50.8 Other manifestations of vitamin A deficiency
0.000 0.992 0.008
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.992 0.008
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.992 0.008
E50.5 Vitamin A deficiency with night blindness
0.000 0.992 0.008
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.992 0.008
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.992 0.008
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.992 0.008
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.992 0.008
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.992 0.008
E51.9 Thiamine deficiency, unspecified
0.000 0.992 0.008
E51.8 Other manifestations of thiamine deficiency
0.000 0.992 0.008
E51.2 Wernicke's encephalopathy
0.000 0.992 0.008
E51.1 Beriberi
0.000 0.992 0.008
E56.9 Vitamin deficiency, unspecified
0.000 0.992 0.008
E56.8 Deficiency of other vitamins
0.000 0.992 0.008
E56.1 Deficiency of vitamin K
0.000 0.992 0.008
E56.0 Deficiency of vitamin E
0.000 0.992 0.008
E63.9 Nutritional deficiency, unspecified
0.000 0.992 0.008
E63.8 Other specified nutritional deficiencies
0.000 0.992 0.008
E63.1 Imbalance of constituents of food intake
0.000 0.992 0.008
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.992 0.008
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.992 0.008
E64.8 Sequelae of other nutritional deficiencies
0.000 0.992 0.008
E64.3 Sequelae of rickets
0.000 0.992 0.008
E64.2 Sequelae of vitamin C deficiency
0.000 0.992 0.008
E64.1 Sequelae of vitamin A deficiency
0.000 0.992 0.008
E64.0 Sequelae of protein-energy malnutrition
0.000 0.992 0.008
E28 Ovarian dysfunction
0.000 0.992 0.008
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.992 0.008
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.992 0.008
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.992 0.008
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.992 0.008
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.992 0.008
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.992 0.008
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.992 0.008
T36 Poisoning by systemic antibiotics
0.000 0.992 0.008
Z43.3 Attention to colostomy
0.008 0.992 0.000
E29 Testicular dysfunction
0.000 0.992 0.008
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.992 0.008
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.992 0.008
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.992 0.008
T39.4 Antirheumatics, not elsewhere classified
0.000 0.992 0.008
T39.2 Pyrazolone derivatives
0.000 0.992 0.008
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.992 0.008
E44.1 Mild protein-energy malnutrition
0.000 0.992 0.007
E44.0 Moderate protein-energy malnutrition
0.000 0.992 0.007
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.992 0.007
E32 Diseases of thymus
0.000 0.992 0.007
E31 Polyglandular dysfunction
0.000 0.992 0.007
E30 Disorders of puberty, not elsewhere classified
0.000 0.992 0.007
E25 Adrenogenital disorders
0.000 0.992 0.007
E20 Hypoparathyroidism
0.000 0.992 0.007
E24 Cushing's syndrome
0.000 0.993 0.007
E67 Other hyperalimentation
0.000 0.993 0.007
E68 Sequelae of hyperalimentation
0.000 0.993 0.007
E65 Localised adiposity
0.000 0.993 0.007
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.993 0.007
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.993 0.007
E16.4 Abnormal secretion of gastrin
0.000 0.993 0.007
E16.3 Increased secretion of glucagon
0.000 0.993 0.007
E16.1 Other hypoglycaemia
0.000 0.993 0.007
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.993 0.007
C44 Other malignant neoplasms of skin
0.000 0.993 0.007
E16.2 Hypoglycaemia, unspecified
0.000 0.993 0.007
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.993 0.007
E26 Hyperaldosteronism
0.000 0.993 0.007
E22 Hyperfunction of pituitary gland
0.000 0.993 0.007
E53.9 Vitamin B deficiency, unspecified
0.000 0.993 0.007
E53.1 Pyridoxine deficiency
0.000 0.993 0.007
E53.0 Riboflavin deficiency
0.000 0.993 0.007
M81.99 Osteoporosis, unspecified (Site unspecified)
0.007 0.993 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.993 0.007
H52.1 Myopia
0.000 0.993 0.007
E34 Other endocrine disorders
0.000 0.993 0.006
T40.4 Other synthetic narcotics
0.000 0.993 0.007
C44.4 Skin of scalp and neck
0.000 0.993 0.007
E23.0 Hypopituitarism
0.000 0.993 0.007
C44.0 Skin of lip
0.000 0.993 0.007
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.993 0.006
T40.8 Lysergide [LSD]
0.000 0.993 0.006
T40.7 Cannabis (derivatives)
0.000 0.993 0.006
T40.5 Cocaine
0.000 0.993 0.006
T40.3 Methadone
0.000 0.993 0.006
T40.1 Heroin
0.000 0.993 0.006
T40.0 Opium
0.000 0.993 0.006
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.993 0.006
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.993 0.007
E27 Other disorders of adrenal gland
0.000 0.993 0.006
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.993 0.006
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.993 0.006
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.993 0.006
T42.3 Barbiturates
0.000 0.993 0.006
T42.2 Succinimides and oxazolidinediones
0.000 0.993 0.006
T42.1 Iminostilbenes
0.000 0.993 0.006
T42.0 Hydantoin derivatives
0.000 0.993 0.006
T42.4 Benzodiazepines
0.000 0.994 0.006
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.994 0.006
E00 Congenital iodine-deficiency syndrome
0.000 0.994 0.006
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.994 0.006
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.994 0.006
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.994 0.006
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.994 0.006
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.994 0.006
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.994 0.006
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.994 0.006
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.994 0.006
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.994 0.006
T44.0 Anticholinesterase agents
0.000 0.994 0.006
E29.1 Testicular hypofunction
0.000 0.994 0.006
E23.7 Disorder of pituitary gland, unspecified
0.000 0.994 0.006
E23.6 Other disorders of pituitary gland
0.000 0.994 0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.994 0.006
E23.1 Drug-induced hypopituitarism
0.000 0.994 0.006
E06 Thyroiditis
0.000 0.994 0.006
E03 Other hypothyroidism
0.000 0.994 0.006
E23.2 Diabetes insipidus
0.000 0.994 0.006
E28.9 Ovarian dysfunction, unspecified
0.000 0.994 0.006
E28.8 Other ovarian dysfunction
0.000 0.994 0.006
E28.1 Androgen excess
0.000 0.994 0.006
E28.0 Oestrogen excess
0.000 0.994 0.006
T36.9 Systemic antibiotic, unspecified
0.000 0.994 0.006
T36.8 Other systemic antibiotics
0.000 0.994 0.006
T36.7 Antifungal antibiotics, systemically used
0.000 0.994 0.006
T36.6 Rifamycins
0.000 0.994 0.006
T36.5 Aminoglycosides
0.000 0.994 0.006
T36.4 Tetracyclines
0.000 0.994 0.006
T36.3 Macrolides
0.000 0.994 0.006
T36.2 Chloramphenicol group
0.000 0.994 0.006
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.994 0.006
T36.0 Penicillins
0.000 0.994 0.006
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.994 0.006
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.994 0.006
T37.5 Antiviral drugs
0.000 0.994 0.006
T37.4 Anthelminthics
0.000 0.994 0.006
T37.3 Other antiprotozoal drugs
0.000 0.994 0.006
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.994 0.006
T37.1 Antimycobacterial drugs
0.000 0.994 0.006
T37.0 Sulphonamides
0.000 0.994 0.006
T41.5 Therapeutic gases
0.000 0.994 0.006
T41.4 Anaesthetic, unspecified
0.000 0.994 0.006
T41.3 Local anaesthetics
0.000 0.994 0.006
T41.2 Other and unspecified general anaesthetics
0.000 0.994 0.006
T41.1 Intravenous anaesthetics
0.000 0.994 0.006
T41.0 Inhaled anaesthetics
0.000 0.994 0.006
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.994 0.006
T45.8 Other primarily systemic and haematological agents
0.000 0.994 0.006
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.994 0.006
T45.6 Fibrinolysis-affecting drugs
0.000 0.994 0.006
T45.5 Anticoagulants
0.000 0.994 0.006
T45.4 Iron and its compounds
0.000 0.994 0.006
T45.3 Enzymes, not elsewhere classified
0.000 0.994 0.006
T45.2 Vitamins, not elsewhere classified
0.000 0.994 0.006
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.994 0.006
T45.0 Antiallergic and antiemetic drugs
0.000 0.994 0.006
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.994 0.006
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.994 0.006
T46.7 Peripheral vasodilators
0.000 0.994 0.006
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.994 0.006
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.994 0.006
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.994 0.006
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.994 0.006
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.994 0.006
T46.1 Calcium-channel blockers
0.000 0.994 0.006
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.994 0.006
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.994 0.006
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.994 0.006
T47.7 Emetics
0.000 0.994 0.006
T47.6 Antidiarrhoeal drugs
0.000 0.994 0.006
T47.5 Digestants
0.000 0.994 0.006
T47.4 Other laxatives
0.000 0.994 0.006
T47.3 Saline and osmotic laxatives
0.000 0.994 0.006
T47.2 Stimulant laxatives
0.000 0.994 0.006
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.994 0.006
T47.0 Histamine H(2)-receptor antagonists
0.000 0.994 0.006
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.994 0.006
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.994 0.006
T48.5 Anti-common-cold drugs
0.000 0.994 0.006
T48.4 Expectorants
0.000 0.994 0.006
T48.3 Antitussives
0.000 0.994 0.006
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.994 0.006
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.994 0.006
T48.0 Oxytocic drugs
0.000 0.994 0.006
T49.9 Topical agent, unspecified
0.000 0.994 0.006
T49.8 Other topical agents
0.000 0.994 0.006
T49.7 Dental drugs, topically applied
0.000 0.994 0.006
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.994 0.006
T49.5 Ophthalmological drugs and preparations
0.000 0.994 0.006
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.994 0.006
T49.3 Emollients, demulcents and protectants
0.000 0.994 0.006
T49.2 Local astringents and local detergents
0.000 0.994 0.006
T49.1 Antipruritics
0.000 0.994 0.006
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.994 0.006
M81.9 Osteoporosis, unspecified
0.006 0.994 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.994 0.006
E29.9 Testicular dysfunction, unspecified
0.000 0.994 0.006
E29.8 Other testicular dysfunction
0.000 0.994 0.006
E29.0 Testicular hyperfunction
0.000 0.994 0.006
E53.8 Deficiency of other specified B group vitamins
0.000 0.994 0.006
T38.9 Other and unspecified hormone antagonists
0.000 0.994 0.006
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.994 0.006
T38.7 Androgens and anabolic congeners
0.000 0.994 0.006
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.994 0.006
T38.5 Other oestrogens and progestogens
0.000 0.994 0.006
T38.4 Oral contraceptives
0.000 0.994 0.006
T38.2 Antithyroid drugs
0.000 0.994 0.006
T38.1 Thyroid hormones and substitutes
0.000 0.994 0.006
T38.0 Glucocorticoids and synthetic analogues
0.000 0.994 0.006
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.994 0.006
T50.8 Diagnostic agents
0.000 0.994 0.006
T50.7 Analeptics and opioid receptor antagonists
0.000 0.994 0.006
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.994 0.006
T50.5 Appetite depressants
0.000 0.994 0.006
T50.4 Drugs affecting uric acid metabolism
0.000 0.994 0.006
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.994 0.006
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.994 0.006
T50.1 Loop [high-ceiling] diuretics
0.000 0.994 0.006
T50.0 Mineralocorticoids and their antagonists
0.000 0.994 0.006
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.994 0.006
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.994 0.005
E07 Other disorders of thyroid
0.000 0.994 0.006
E20.9 Hypoparathyroidism, unspecified
0.000 0.994 0.005
E20.8 Other hypoparathyroidism
0.000 0.994 0.005
E20.1 Pseudohypoparathyroidism
0.000 0.994 0.005
E20.0 Idiopathic hypoparathyroidism
0.000 0.994 0.005
E25.9 Adrenogenital disorder, unspecified
0.000 0.994 0.005
E25.8 Other adrenogenital disorders
0.000 0.994 0.005
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.994 0.005
E30.9 Disorder of puberty, unspecified
0.000 0.994 0.005
E30.8 Other disorders of puberty
0.000 0.994 0.005
E30.1 Precocious puberty
0.000 0.994 0.005
E30.0 Delayed puberty
0.000 0.994 0.005
E31.9 Polyglandular dysfunction, unspecified
0.000 0.994 0.005
E31.8 Other polyglandular dysfunction
0.000 0.994 0.005
E31.1 Polyglandular hyperfunction
0.000 0.994 0.005
E31.0 Autoimmune polyglandular failure
0.000 0.994 0.005
E32.9 Disease of thymus, unspecified
0.000 0.994 0.005
E32.8 Other diseases of thymus
0.000 0.994 0.005
E32.1 Abscess of thymus
0.000 0.994 0.005
E32.0 Persistent hyperplasia of thymus
0.000 0.994 0.005
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.994 0.005
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.994 0.005
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.994 0.005
E24.8 Other Cushing's syndrome
0.000 0.994 0.005
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.994 0.005
E24.3 Ectopic ACTH syndrome
0.000 0.994 0.005
E24.2 Drug-induced Cushing's syndrome
0.000 0.994 0.005
E24.1 Nelson's syndrome
0.000 0.994 0.005
E24.0 Pituitary-dependent Cushing's disease
0.000 0.994 0.005
E67.8 Other specified hyperalimentation
0.000 0.994 0.005
E67.3 Hypervitaminosis D
0.000 0.994 0.005
E67.2 Megavitamin-B6 syndrome
0.000 0.994 0.005
E67.1 Hypercarotenaemia
0.000 0.994 0.005
E67.0 Hypervitaminosis A
0.000 0.994 0.005
T40.6 Other and unspecified narcotics
0.000 0.994 0.005
C44.7 Skin of lower limb, including hip
0.000 0.994 0.006
E24.9 Cushing's syndrome, unspecified
0.000 0.994 0.005
C44.8 Overlapping lesion of skin
0.000 0.994 0.005
E26.9 Hyperaldosteronism, unspecified
0.000 0.995 0.005
E26.8 Other hyperaldosteronism
0.000 0.995 0.005
E26.1 Secondary hyperaldosteronism
0.000 0.995 0.005
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.995 0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.995 0.005
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.995 0.005
E22.8 Other hyperfunction of pituitary gland
0.000 0.995 0.005
E22.1 Hyperprolactinaemia
0.000 0.995 0.005
E22.0 Acromegaly and pituitary gigantism
0.000 0.995 0.005
C44.2 Skin of ear and external auricular canal
0.000 0.995 0.005
C44.1 Skin of eyelid, including canthus
0.000 0.995 0.005
E26.0 Primary hyperaldosteronism
0.000 0.995 0.005
M81.98 Osteoporosis, unspecified (Other)
0.005 0.995 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.995 0.005
E34.9 Endocrine disorder, unspecified
0.000 0.995 0.005
E34.8 Other specified endocrine disorders
0.000 0.995 0.005
E34.5 Androgen resistance syndrome
0.000 0.995 0.005
E34.4 Constitutional tall stature
0.000 0.995 0.005
E34.3 Short stature, not elsewhere classified
0.000 0.995 0.005
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.995 0.005
E34.1 Other hypersecretion of intestinal hormones
0.000 0.995 0.005
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.995 0.005
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.995 0.005
E05.8 Other thyrotoxicosis
0.000 0.995 0.005
E05.5 Thyroid crisis or storm
0.000 0.995 0.005
E05.4 Thyrotoxicosis factitia
0.000 0.995 0.005
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.995 0.005
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.995 0.005
E27.8 Other specified disorders of adrenal gland
0.000 0.995 0.005
E27.5 Adrenomedullary hyperfunction
0.000 0.995 0.005
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.995 0.005
E27.2 Addisonian crisis
0.000 0.995 0.005
E27.0 Other adrenocortical overactivity
0.000 0.995 0.005
E28.3 Primary ovarian failure
0.000 0.995 0.004
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.995 0.005
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.995 0.005
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.995 0.005
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.995 0.005
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.995 0.005
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.995 0.005
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.995 0.005
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.995 0.005
H52 Disorders of refraction and accommodation
0.000 0.995 0.005
R00.2 Palpitations
0.005 0.995 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.005 0.995 0.000
R00 Abnormalities of heart beat
0.005 0.995 0.000
E06.9 Thyroiditis, unspecified
0.000 0.995 0.004
E06.5 Other chronic thyroiditis
0.000 0.995 0.004
E06.4 Drug-induced thyroiditis
0.000 0.995 0.004
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.995 0.004
E06.1 Subacute thyroiditis
0.000 0.995 0.004
E06.0 Acute thyroiditis
0.000 0.995 0.004
E03.5 Myxoedema coma
0.000 0.995 0.004
E03.4 Atrophy of thyroid (acquired)
0.000 0.995 0.004
E03.3 Postinfectious hypothyroidism
0.000 0.995 0.004
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.995 0.004
E03.1 Congenital hypothyroidism without goitre
0.000 0.995 0.004
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.995 0.004
M25.77 Osteophyte (Ankle and foot)
0.005 0.995 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.004 0.995 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.004 0.995 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.004 0.995 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.004 0.995 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.004 0.995 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.004 0.995 0.000
E03.8 Other specified hypothyroidism
0.000 0.995 0.004
E34.0 Carcinoid syndrome
0.001 0.996 0.004
C44.6 Skin of upper limb, including shoulder
0.000 0.996 0.004
Z43 Attention to artificial openings
0.004 0.996 0.000
E07.8 Other specified disorders of thyroid
0.000 0.996 0.004
E07.1 Dyshormogenetic goitre
0.000 0.996 0.004
E07.0 Hypersecretion of calcitonin
0.000 0.996 0.004
Z43.2 Attention to ileostomy
0.004 0.996 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.996 0.004
E06.3 Autoimmune thyroiditis
0.000 0.996 0.004
A41.5 Septicaemia due to other Gram-negative organisms
0.000 0.996 0.004
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.996 0.004
E21.4 Other specified disorders of parathyroid gland
0.000 0.996 0.004
E21.2 Other hyperparathyroidism
0.000 0.996 0.004
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.996 0.004
H52.0 Hypermetropia
0.000 0.996 0.004
H52.3 Anisometropia and aniseikonia
0.000 0.996 0.004
C44.3 Skin of other and unspecified parts of face
0.000 0.996 0.004
E27.9 Disorder of adrenal gland, unspecified
0.001 0.996 0.003
C18.2 Ascending colon
0.004 0.996 0.000
E27.1 Primary adrenocortical insufficiency
0.001 0.996 0.003
G47.9 Sleep disorder, unspecified
0.004 0.996 0.000
E66 Obesity
0.000 0.996 0.004
E21.0 Primary hyperparathyroidism
0.000 0.996 0.004
H52.7 Disorder of refraction, unspecified
0.000 0.996 0.004
H52.6 Other disorders of refraction
0.000 0.996 0.004
H52.5 Disorders of accommodation
0.000 0.996 0.004
H52.4 Presbyopia
0.000 0.996 0.004
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.996 0.004
E07.9 Disorder of thyroid, unspecified
0.000 0.996 0.003
E04 Other non-toxic goitre
0.000 0.996 0.003
H52.2 Astigmatism
0.000 0.996 0.003
Z43.1 Attention to gastrostomy
0.003 0.996 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.996 0.003
C18 Malignant neoplasm of colon
0.004 0.996 0.000
I51 Complications and ill-defined descriptions of heart disease
0.003 0.997 0.000
C18.4 Transverse colon
0.003 0.997 0.000
C18.9 Colon, unspecified
0.003 0.997 0.000
Z43.9 Attention to unspecified artificial opening
0.003 0.997 0.000
Z43.8 Attention to other artificial openings
0.003 0.997 0.000
Z43.7 Attention to artificial vagina
0.003 0.997 0.000
Z43.5 Attention to cyctostomy
0.003 0.997 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.003 0.997 0.000
Z43.0 Attention to tracheostomy
0.003 0.997 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.000 0.997 0.003
H53.2 Diplopia
0.000 0.997 0.003
I51.6 Cardiovascular disease, unspecified
0.003 0.997 0.000
M81 Osteoporosis without pathological fracture
0.003 0.997 0.000
H61.0 Perichondritis of external ear
0.003 0.997 0.000
C43 Malignant melanoma of skin
0.000 0.997 0.003
A41 Other septicaemia
0.000 0.997 0.003
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.997 0.003
I49.0 Ventricular fibrillation and flutter
0.003 0.997 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.997 0.003
E66.1 Drug-induced obesity
0.000 0.997 0.003
E66.0 Obesity due to excess calories
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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