TreeWAS – Variant ID: rs61839660

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.015	0.985
E10 Insulin-dependent diabetes mellitus	0.000	0.015	0.985
E10.3 With ophthalmic complications	0.000	0.029	0.971
E10.1 With ketoacidosis	0.000	0.044	0.956
E10.4 With neurological complications	0.000	0.182	0.818
E10.5 With peripheral circulatory complications	0.000	0.185	0.815
E10.2 With renal complications	0.000	0.192	0.808
E10.8 With unspecified complications	0.000	0.281	0.719
E10.7 With multiple complications	0.000	0.294	0.706
E10.6 With other specified complications	0.000	0.294	0.706
E10.0 With coma	0.000	0.413	0.586
E10-E14 Diabetes mellitus	0.000	0.552	0.448
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.629	0.371
E00-E07 Disorders of thyroid gland	0.000	0.637	0.363
E20-E35 Disorders of other endocrine glands	0.000	0.642	0.358
E03 Other hypothyroidism	0.000	0.654	0.346
E03.9 Hypothyroidism, unspecified	0.000	0.669	0.331
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.674	0.326
E12 Malnutrition-related diabetes mellitus	0.000	0.678	0.321
E13 Other specified diabetes mellitus	0.000	0.693	0.307
E22 Hyperfunction of pituitary gland	0.000	0.694	0.306
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.699	0.301
E28 Ovarian dysfunction	0.000	0.701	0.299
E24 Cushing's syndrome	0.000	0.702	0.298
E06 Thyroiditis	0.000	0.706	0.294
E26 Hyperaldosteronism	0.000	0.715	0.285
E40-E46 Malnutrition	0.000	0.727	0.273
E03.8 Other specified hypothyroidism	0.000	0.729	0.271
E22.0 Acromegaly and pituitary gigantism	0.000	0.730	0.270
E27 Other disorders of adrenal gland	0.000	0.731	0.269
E23 Hypofunction and other disorders of pituitary gland	0.000	0.736	0.264
E29 Testicular dysfunction	0.000	0.736	0.264
E34 Other endocrine disorders	0.000	0.739	0.261
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.740	0.260
E00 Congenital iodine-deficiency syndrome	0.000	0.740	0.260
E20 Hypoparathyroidism	0.000	0.742	0.258
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.743	0.257
E32 Diseases of thymus	0.000	0.743	0.257
E31 Polyglandular dysfunction	0.000	0.743	0.257
E30 Disorders of puberty, not elsewhere classified	0.000	0.743	0.257
E25 Adrenogenital disorders	0.000	0.743	0.257
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.743	0.257
E24.9 Cushing's syndrome, unspecified	0.000	0.744	0.256
E07 Other disorders of thyroid	0.000	0.745	0.255
E28.2 Polycystic ovarian syndrome	0.000	0.749	0.251
E03.5 Myxoedema coma	0.000	0.752	0.248
E03.4 Atrophy of thyroid (acquired)	0.000	0.752	0.248
E03.3 Postinfectious hypothyroidism	0.000	0.752	0.248
E03.1 Congenital hypothyroidism without goitre	0.000	0.752	0.248
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.752	0.248
E06.3 Autoimmune thyroiditis	0.000	0.754	0.246
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.755	0.244
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.760	0.240
E04 Other non-toxic goitre	0.000	0.763	0.237
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.763	0.236
E05.5 Thyroid crisis or storm	0.000	0.766	0.233
E05.4 Thyrotoxicosis factitia	0.000	0.766	0.233
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.766	0.233
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.766	0.233
E26.0 Primary hyperaldosteronism	0.000	0.767	0.233
E22.1 Hyperprolactinaemia	0.000	0.767	0.233
E12.9 Without complications	0.000	0.769	0.231
E12.8 With unspecified complications	0.000	0.769	0.231
E12.7 With multiple complications	0.000	0.769	0.231
E12.6 With other specified complications	0.000	0.769	0.231
E12.5 With peripheral circulatory complications	0.000	0.769	0.231
E12.4 With neurological complications	0.000	0.769	0.231
E12.3 With ophthalmic complications	0.000	0.769	0.231
E12.2 With renal complications	0.000	0.769	0.231
E12.1 With ketoacidosis	0.000	0.769	0.231
E12.0 With coma	0.000	0.769	0.231
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.770	0.230
E28.3 Primary ovarian failure	0.000	0.774	0.225
E27.8 Other specified disorders of adrenal gland	0.000	0.778	0.222
E05.9 Thyrotoxicosis, unspecified	0.000	0.778	0.222
E13.8 With unspecified complications	0.000	0.779	0.220
E13.7 With multiple complications	0.000	0.779	0.220
E13.6 With other specified complications	0.000	0.779	0.220
E13.5 With peripheral circulatory complications	0.000	0.779	0.220
E13.4 With neurological complications	0.000	0.779	0.220
E13.3 With ophthalmic complications	0.000	0.779	0.220
E13.2 With renal complications	0.000	0.779	0.220
E13.1 With ketoacidosis	0.000	0.779	0.220
E13.0 With coma	0.000	0.779	0.220
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.780	0.220
E22.8 Other hyperfunction of pituitary gland	0.000	0.780	0.220
E23.2 Diabetes insipidus	0.000	0.781	0.219
E28.9 Ovarian dysfunction, unspecified	0.000	0.785	0.215
E28.8 Other ovarian dysfunction	0.000	0.785	0.215
E28.1 Androgen excess	0.000	0.785	0.215
E28.0 Oestrogen excess	0.000	0.785	0.215
E24.8 Other Cushing's syndrome	0.000	0.786	0.214
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.786	0.214
E24.3 Ectopic ACTH syndrome	0.000	0.786	0.214
E24.2 Drug-induced Cushing's syndrome	0.000	0.786	0.214
E24.1 Nelson's syndrome	0.000	0.786	0.214
E24.0 Pituitary-dependent Cushing's disease	0.000	0.786	0.214
E50-E64 Other nutritional deficiencies	0.000	0.787	0.212
E06.5 Other chronic thyroiditis	0.000	0.789	0.211
E06.4 Drug-induced thyroiditis	0.000	0.789	0.211
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.789	0.211
E06.1 Subacute thyroiditis	0.000	0.789	0.211
E06.0 Acute thyroiditis	0.000	0.789	0.211
E27.2 Addisonian crisis	0.000	0.790	0.210
E06.9 Thyroiditis, unspecified	0.000	0.791	0.209
E05.8 Other thyrotoxicosis	0.000	0.793	0.207
E13.9 Without complications	0.000	0.793	0.206
E26.9 Hyperaldosteronism, unspecified	0.000	0.795	0.204
E26.8 Other hyperaldosteronism	0.000	0.795	0.204
E26.1 Secondary hyperaldosteronism	0.000	0.795	0.204
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.798	0.202
E46 Unspecified protein-energy malnutrition	0.000	0.798	0.202
E11 Non-insulin-dependent diabetes mellitus	0.000	0.798	0.202
E34.0 Carcinoid syndrome	0.000	0.800	0.200
E27.1 Primary adrenocortical insufficiency	0.000	0.802	0.198
E29.1 Testicular hypofunction	0.000	0.804	0.196
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.804	0.196
E45 Retarded development following protein-energy malnutrition	0.000	0.804	0.196
E43 Unspecified severe protein-energy malnutrition	0.000	0.804	0.196
E42 Marasmic kwashiorkor	0.000	0.804	0.196
E41 Nutritional marasmus	0.000	0.804	0.196
E40 Kwashiorkor	0.000	0.804	0.196
E27.5 Adrenomedullary hyperfunction	0.000	0.807	0.193
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.807	0.193
E27.0 Other adrenocortical overactivity	0.000	0.807	0.193
E04.1 Non-toxic single thyroid nodule	0.000	0.809	0.191
E23.7 Disorder of pituitary gland, unspecified	0.000	0.810	0.189
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.810	0.189
E23.1 Drug-induced hypopituitarism	0.000	0.810	0.189
E29.9 Testicular dysfunction, unspecified	0.000	0.811	0.189
E29.8 Other testicular dysfunction	0.000	0.811	0.189
E29.0 Testicular hyperfunction	0.000	0.811	0.189
E20.9 Hypoparathyroidism, unspecified	0.000	0.813	0.187
E34.8 Other specified endocrine disorders	0.000	0.813	0.187
E34.5 Androgen resistance syndrome	0.000	0.813	0.187
E34.4 Constitutional tall stature	0.000	0.813	0.187
E34.3 Short stature, not elsewhere classified	0.000	0.813	0.187
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.813	0.187
E34.1 Other hypersecretion of intestinal hormones	0.000	0.813	0.187
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.813	0.187
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.813	0.187
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.813	0.187
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.813	0.187
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.813	0.187
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.813	0.187
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.813	0.187
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.813	0.187
E27.9 Disorder of adrenal gland, unspecified	0.000	0.814	0.186
E20.8 Other hypoparathyroidism	0.000	0.814	0.185
E20.1 Pseudohypoparathyroidism	0.000	0.814	0.185
E20.0 Idiopathic hypoparathyroidism	0.000	0.814	0.185
E23.6 Other disorders of pituitary gland	0.000	0.816	0.184
E25.9 Adrenogenital disorder, unspecified	0.000	0.816	0.184
E25.8 Other adrenogenital disorders	0.000	0.816	0.184
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.816	0.184
E30.9 Disorder of puberty, unspecified	0.000	0.816	0.184
E30.8 Other disorders of puberty	0.000	0.816	0.184
E30.1 Precocious puberty	0.000	0.816	0.184
E30.0 Delayed puberty	0.000	0.816	0.184
E31.9 Polyglandular dysfunction, unspecified	0.000	0.816	0.184
E31.8 Other polyglandular dysfunction	0.000	0.816	0.184
E31.1 Polyglandular hyperfunction	0.000	0.816	0.184
E31.0 Autoimmune polyglandular failure	0.000	0.816	0.184
E32.9 Disease of thymus, unspecified	0.000	0.816	0.184
E32.8 Other diseases of thymus	0.000	0.816	0.184
E32.1 Abscess of thymus	0.000	0.816	0.184
E32.0 Persistent hyperplasia of thymus	0.000	0.816	0.184
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.816	0.184
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.816	0.184
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.816	0.184
E07.1 Dyshormogenetic goitre	0.000	0.817	0.183
E07.0 Hypersecretion of calcitonin	0.000	0.817	0.183
E07.8 Other specified disorders of thyroid	0.000	0.819	0.181
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.820	0.180
E07.9 Disorder of thyroid, unspecified	0.000	0.820	0.180
E34.9 Endocrine disorder, unspecified	0.000	0.823	0.177
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.824	0.175
E21.4 Other specified disorders of parathyroid gland	0.000	0.824	0.175
E21.2 Other hyperparathyroidism	0.000	0.824	0.175
E04.9 Non-toxic goitre, unspecified	0.000	0.825	0.175
E65-E68 Obesity and other hyperalimentation	0.000	0.828	0.172
E04.8 Other specified non-toxic goitre	0.000	0.830	0.170
E04.0 Non-toxic diffuse goitre	0.000	0.831	0.168
E21.0 Primary hyperparathyroidism	0.000	0.832	0.168
E11.1 With ketoacidosis	0.000	0.833	0.167
E21.3 Hyperparathyroidism, unspecified	0.000	0.834	0.166
E15 Nondiabetic hypoglycaemic coma	0.000	0.835	0.165
E11.4 With neurological complications	0.000	0.836	0.164
E23.0 Hypopituitarism	0.000	0.840	0.160
E11.2 With renal complications	0.000	0.842	0.158
E14 Unspecified diabetes mellitus	0.000	0.845	0.155
E55 Vitamin D deficiency	0.000	0.845	0.155
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.847	0.152
E63 Other nutritional deficiencies	0.000	0.847	0.152
E56 Other vitamin deficiencies	0.000	0.847	0.152
E51 Thiamine deficiency	0.000	0.847	0.152
E50 Vitamin A deficiency	0.000	0.847	0.152
E60 Dietary zinc deficiency	0.000	0.847	0.152
E59 Dietary selenium deficiency	0.000	0.847	0.152
E58 Dietary calcium deficiency	0.000	0.847	0.152
E54 Ascorbic acid deficiency	0.000	0.847	0.152
E52 Niacin deficiency [pellagra]	0.000	0.847	0.152
M16.1 Other primary coxarthrosis	0.000	0.850	0.150
E11.0 With coma	0.000	0.855	0.145
E11.7 With multiple complications	0.000	0.855	0.145
M16 Coxarthrosis [arthrosis of hip]	0.000	0.858	0.142
E44.1 Mild protein-energy malnutrition	0.000	0.859	0.140
E44.0 Moderate protein-energy malnutrition	0.000	0.859	0.140
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.859	0.140
M16.9 Coxarthrosis, unspecified	0.000	0.861	0.139
E11.5 With peripheral circulatory complications	0.000	0.861	0.139
E61 Deficiency of other nutrient elements	0.000	0.868	0.132
E11.3 With ophthalmic complications	0.000	0.869	0.131
E16 Other disorders of pancreatic internal secretion	0.000	0.871	0.129
E11.8 With unspecified complications	0.000	0.871	0.128
E53 Deficiency of other B group vitamins	0.000	0.876	0.124
E67 Other hyperalimentation	0.000	0.876	0.123
E68 Sequelae of hyperalimentation	0.000	0.876	0.123
L30.9 Dermatitis, unspecified	0.122	0.878	0.000
M16.7 Other secondary coxarthrosis	0.000	0.882	0.118
M16.0 Primary coxarthrosis, bilateral	0.000	0.886	0.114
E55.9 Vitamin D deficiency, unspecified	0.000	0.887	0.113
E14.8 With unspecified complications	0.000	0.889	0.111
E14.7 With multiple complications	0.000	0.889	0.111
E14.6 With other specified complications	0.000	0.889	0.111
E14.5 With peripheral circulatory complications	0.000	0.889	0.111
E14.4 With neurological complications	0.000	0.889	0.111
E14.2 Withrenal complications	0.000	0.889	0.111
E14.1 With ketoacidosis	0.000	0.889	0.111
E14.0 With coma	0.000	0.889	0.111
M16.3 Other dysplastic coxarthrosis	0.000	0.889	0.111
E55.0 Rickets, active	0.000	0.889	0.111
E66 Obesity	0.000	0.890	0.110
E50.9 Vitamin A deficiency, unspecified	0.000	0.890	0.109
E50.8 Other manifestations of vitamin A deficiency	0.000	0.890	0.109
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.890	0.109
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.890	0.109
E50.5 Vitamin A deficiency with night blindness	0.000	0.890	0.109
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.890	0.109
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.890	0.109
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.890	0.109
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.890	0.109
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.890	0.109
E51.9 Thiamine deficiency, unspecified	0.000	0.890	0.109
E51.8 Other manifestations of thiamine deficiency	0.000	0.890	0.109
E51.2 Wernicke's encephalopathy	0.000	0.890	0.109
E51.1 Beriberi	0.000	0.890	0.109
E56.9 Vitamin deficiency, unspecified	0.000	0.890	0.109
E56.8 Deficiency of other vitamins	0.000	0.890	0.109
E56.1 Deficiency of vitamin K	0.000	0.890	0.109
E56.0 Deficiency of vitamin E	0.000	0.890	0.109
E63.9 Nutritional deficiency, unspecified	0.000	0.890	0.109
E63.8 Other specified nutritional deficiencies	0.000	0.890	0.109
E63.1 Imbalance of constituents of food intake	0.000	0.890	0.109
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.890	0.109
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.890	0.109
E64.8 Sequelae of other nutritional deficiencies	0.000	0.890	0.109
E64.3 Sequelae of rickets	0.000	0.890	0.109
E64.2 Sequelae of vitamin C deficiency	0.000	0.890	0.109
E64.1 Sequelae of vitamin A deficiency	0.000	0.890	0.109
E64.0 Sequelae of protein-energy malnutrition	0.000	0.890	0.109
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.898	0.102
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.898	0.102
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.898	0.102
E11.6 With other specified complications	0.000	0.902	0.098
E04.2 Non-toxic multinodular goitre	0.000	0.903	0.097
E61.9 Deficiency of nutrient element, unspecified	0.000	0.905	0.095
E61.8 Deficiency of other specified nutrient elements	0.000	0.905	0.095
E61.7 Deficiency of multiple nutrient elements	0.000	0.905	0.095
E61.6 Vanadium deficiency	0.000	0.905	0.095
E61.5 Molybdenum deficiency	0.000	0.905	0.095
E61.4 Chromium deficiency	0.000	0.905	0.095
E61.3 Manganese deficiency	0.000	0.905	0.095
E61.2 Magnesium deficiency	0.000	0.905	0.095
E61.0 Copper deficiency	0.000	0.905	0.095
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.907	0.093
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.907	0.093
E16.4 Abnormal secretion of gastrin	0.000	0.907	0.093
E16.3 Increased secretion of glucagon	0.000	0.907	0.093
E16.1 Other hypoglycaemia	0.000	0.910	0.090
E53.9 Vitamin B deficiency, unspecified	0.000	0.911	0.089
E53.1 Pyridoxine deficiency	0.000	0.911	0.089
E53.0 Riboflavin deficiency	0.000	0.911	0.089
E67.8 Other specified hyperalimentation	0.000	0.911	0.089
E67.3 Hypervitaminosis D	0.000	0.911	0.089
E67.2 Megavitamin-B6 syndrome	0.000	0.911	0.089
E67.1 Hypercarotenaemia	0.000	0.911	0.089
E67.0 Hypervitaminosis A	0.000	0.911	0.089
M16.5 Other posttraumatic coxarthrosis	0.000	0.911	0.088
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.914	0.086
L30 Other dermatitis	0.080	0.920	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.921	0.079
E66.1 Drug-induced obesity	0.000	0.921	0.079
E66.8 Other obesity	0.000	0.921	0.079
E66.0 Obesity due to excess calories	0.000	0.925	0.075
E14.3 With ophthalmic complications	0.000	0.925	0.075
E61.1 Iron deficiency	0.000	0.926	0.074
E16.2 Hypoglycaemia, unspecified	0.000	0.928	0.072
E66.9 Obesity, unspecified	0.000	0.929	0.071
L30.3 Infective dermatitis	0.065	0.935	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.939	0.061
L30.8 Other specified dermatitis	0.061	0.939	0.000
E65 Localised adiposity	0.001	0.939	0.060
L30.5 Pityriasis alba	0.058	0.942	0.000
L30.4 Erythema intertrigo	0.058	0.942	0.000
L30.2 Cutaneous autosensitisation	0.058	0.942	0.000
L30.1 Dyshidrosis [pompholyx]	0.058	0.942	0.000
L30.0 Nummular dermatitis	0.058	0.942	0.000
K22.1 Ulcer of oesophagus	0.043	0.957	0.000
E14.9 Without complications	0.000	0.960	0.040
K22.7 Barrett's oesophagus	0.033	0.967	0.000
E70-E90 Metabolic disorders	0.000	0.968	0.032
E89.0 Postprocedural hypothyroidism	0.000	0.969	0.031
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.969	0.031
L20-L30 Dermatitis and eczema	0.029	0.971	0.000
K22 Other diseases of oesophagus	0.029	0.971	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.028	0.972	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.972	0.028
K22.9 Disease of oesophagus, unspecified	0.027	0.973	0.000
L23 Allergic contact dermatitis	0.026	0.974	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.975	0.025
E84 Cystic fibrosis	0.000	0.976	0.023
E79 Disorders of purine and pyrimidine metabolism	0.000	0.976	0.023
E77 Disorders of glycoprotein metabolism	0.000	0.976	0.023
E76 Disorders of glycosaminoglycan metabolism	0.000	0.976	0.023
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.976	0.023
E72 Other disorders of amino-acid metabolism	0.000	0.976	0.023
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.976	0.023
E70 Disorders of aromatic amino-acid metabolism	0.000	0.976	0.023
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.976	0.023
E85 Amyloidosis	0.000	0.977	0.023
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.977	0.022
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.977	0.022
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.977	0.022
E89.5 Postprocedural testicular hypofunction	0.000	0.977	0.022
E89.4 Postprocedural ovarian failure	0.000	0.977	0.022
E89.1 Postprocedural hypoinsulinaemia	0.000	0.977	0.022
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.978	0.022
L20 Atopic dermatitis	0.022	0.978	0.000
I67.8 Other specified cerebrovascular diseases	0.022	0.978	0.000
E73 Lactose intolerance	0.000	0.978	0.022
C43.7 Malignant melanoma of lower limb, including hip	0.022	0.978	0.000
C43 Malignant melanoma of skin	0.022	0.978	0.000
M20.2 Hallux rigidus	0.000	0.978	0.022
E89.3 Postprocedural hypopituitarism	0.000	0.978	0.022
L23.1 Allergic contact dermatitis due to adhesives	0.022	0.978	0.000
M20 Acquired deformities of fingers and toes	0.000	0.978	0.022
L23.5 Allergic contact dermatitis due to other chemical products	0.021	0.979	0.000
L24 Irritant contact dermatitis	0.021	0.979	0.000
L26 Exfoliative dermatitis	0.021	0.979	0.000
L22 Diaper [napkin] dermatitis	0.021	0.979	0.000
E88 Other metabolic disorders	0.000	0.979	0.021
E11.9 Without complications	0.000	0.979	0.021
L25 Unspecified contact dermatitis	0.021	0.979	0.000
K22.3 Perforation of oesophagus	0.021	0.979	0.000
L28 Lichen simplex chronicus and prurigo	0.021	0.979	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.979	0.021
I61.9 Intracerebral haemorrhage, unspecified	0.020	0.980	0.000
K22.0 Achalasia of cardia	0.020	0.980	0.000
I67 Other cerebrovascular diseases	0.020	0.980	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.980	0.020
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.980	0.020
C44.5 Skin of trunk	0.020	0.980	0.000
L21 Seborrhoeic dermatitis	0.020	0.980	0.000
C43.9 Malignant melanoma of skin, unspecified	0.019	0.981	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.981	0.019
C43.6 Malignant melanoma of upper limb, including shoulder	0.019	0.981	0.000
I60-I69 Cerebrovascular diseases	0.019	0.981	0.000
C44 Other malignant neoplasms of skin	0.019	0.981	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.019	0.981	0.000
L23.8 Allergic contact dermatitis due to other agents	0.019	0.981	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.019	0.981	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.019	0.981	0.000
L23.4 Allergic contact dermatitis due to dyes	0.019	0.981	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.019	0.981	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.019	0.981	0.000
L23.0 Allergic contact dermatitis due to metals	0.019	0.981	0.000
M15-M19 Arthrosis	0.000	0.981	0.019
M19.0 Primary arthrosis of other joints	0.000	0.981	0.019
C43-C44 Melanoma and other malignant neoplasms of skin	0.018	0.982	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.982	0.018
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.982	0.018
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.982	0.018
E74.2 Disorders of galactose metabolism	0.000	0.982	0.018
E74.1 Disorders of fructose metabolism	0.000	0.982	0.018
E74.0 Glycogen storage disease	0.000	0.982	0.018
I61 Intracerebral haemorrhage	0.018	0.982	0.000
L29 Pruritus	0.018	0.982	0.000
E85.9 Amyloidosis, unspecified	0.000	0.983	0.017
L20.9 Atopic dermatitis, unspecified	0.017	0.983	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.983	0.017
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.983	0.017
E70.3 Albinism	0.000	0.983	0.017
E70.2 Disorders of tyrosine metabolism	0.000	0.983	0.017
E70.1 Other hyperphenylalaninaemias	0.000	0.983	0.017
E70.0 Classical phenylketonuria	0.000	0.983	0.017
E71.3 Disorders of fatty-acid metabolism	0.000	0.983	0.017
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.983	0.017
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.983	0.017
E71.0 Maple-syrup-urine disease	0.000	0.983	0.017
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.983	0.017
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.983	0.017
E72.5 Disorders of glycine metabolism	0.000	0.983	0.017
E72.4 Disorders of ornithine metabolism	0.000	0.983	0.017
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.983	0.017
E72.2 Disorders of urea cycle metabolism	0.000	0.983	0.017
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.983	0.017
E72.0 Disorders of amino-acid transport	0.000	0.983	0.017
E75.6 Lipid storage disorder, unspecified	0.000	0.983	0.017
E75.5 Other lipid storage disorders	0.000	0.983	0.017
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.983	0.017
E75.3 Sphingolipidosis, unspecified	0.000	0.983	0.017
E75.2 Other sphingolipidosis	0.000	0.983	0.017
E75.1 Other gangliosidosis	0.000	0.983	0.017
E75.0 GM2 gangliosidosis	0.000	0.983	0.017
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.983	0.017
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.983	0.017
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.983	0.017
E76.2 Other mucopolysaccharidoses	0.000	0.983	0.017
E76.1 Mucopolysaccharidosis, type II	0.000	0.983	0.017
E76.0 Mucopolysaccharidosis, type I	0.000	0.983	0.017
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.983	0.017
E77.8 Other disorders of glycoprotein metabolism	0.000	0.983	0.017
E77.1 Defects in glycoprotein degradation	0.000	0.983	0.017
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.983	0.017
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.983	0.017
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.983	0.017
E79.1 Lesch-Nyhan syndrome	0.000	0.983	0.017
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.983	0.017
E84.9 Cystic fibrosis, unspecified	0.000	0.983	0.017
E84.8 Cystic fibrosis with other manifestations	0.000	0.983	0.017
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.983	0.017
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.983	0.017
C43.5 Malignant melanoma of trunk	0.017	0.983	0.000
C44.2 Skin of ear and external auricular canal	0.017	0.983	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.017	0.983	0.000
I67.1 Cerebral aneurysm, nonruptured	0.017	0.983	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.017	0.983	0.000
E85.8 Other amyloidosis	0.000	0.983	0.017
E85.3 Secondary systemic amyloidosis	0.000	0.983	0.017
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.983	0.017
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.983	0.017
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.983	0.017
I60 Subarachnoid haemorrhage	0.017	0.983	0.000
C44.4 Skin of scalp and neck	0.017	0.983	0.000
I67.2 Cerebral atherosclerosis	0.016	0.983	0.000
M19 Other arthrosis	0.000	0.984	0.016
I63 Cerebral infarction	0.016	0.984	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.984	0.016
E80.6 Other disorders of bilirubin metabolism	0.000	0.984	0.016
E80.5 Crigler-Najjar syndrome	0.000	0.984	0.016
E80.3 Defects of catalase and peroxydase	0.000	0.984	0.016
E80.2 Other porphyria	0.000	0.984	0.016
E80.1 Porphyria cutanea tarda	0.000	0.984	0.016
E80.0 Hereditary erythropoietic porphyria	0.000	0.984	0.016
L20.8 Other atopic dermatitis	0.016	0.984	0.000
L20.0 Besnier's prurigo	0.016	0.984	0.000
E73.8 Other lactose intolerance	0.000	0.984	0.016
E73.1 Secondary lactase deficiency	0.000	0.984	0.016
E73.0 Congenital lactase deficiency	0.000	0.984	0.016
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.016	0.984	0.000
C43.8 Overlapping malignant melanoma of skin	0.016	0.984	0.000
C43.0 Malignant melanoma of lip	0.016	0.984	0.000
I63.9 Cerebral infarction, unspecified	0.016	0.984	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.984	0.016
E85.4 Organ-limited amyloidosis	0.000	0.984	0.015
L24.9 Irritant contact dermatitis, unspecified cause	0.015	0.984	0.000
L24.8 Irritant contact dermatitis due to other agents	0.015	0.984	0.000
L24.7 Irritant contact dermatitis due to plants, except food	0.015	0.984	0.000
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.015	0.984	0.000
L24.5 Irritant contact dermatitis due to other chemical products	0.015	0.984	0.000
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.015	0.984	0.000
L24.3 Irritant contact dermatitis due to cosmetics	0.015	0.984	0.000
L24.2 Irritant contact dermatitis due to solvents	0.015	0.984	0.000
L24.1 Irritant contact dermatitis due to oils and greases	0.015	0.984	0.000
L24.0 Irritant contact dermatitis due to detergents	0.015	0.984	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.984	0.015
E88.8 Other specified metabolic disorders	0.000	0.984	0.015
E88.3 Tumour lysis syndrome	0.000	0.984	0.015
E88.2 Lipomatosis, not elsewhere classified	0.000	0.984	0.015
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.984	0.015
L28.0 Lichen simplex chronicus	0.015	0.985	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.985	0.015
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.985	0.015
L25.8 Unspecified contact dermatitis due to other agents	0.015	0.985	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.015	0.985	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.015	0.985	0.000
L25.3 Unspecified contact dermatitis due to other chemical products	0.015	0.985	0.000
L25.2 Unspecified contact dermatitis due to dyes	0.015	0.985	0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.015	0.985	0.000
L25.0 Unspecified contact dermatitis due to cosmetics	0.015	0.985	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.015	0.985	0.000
M20.0 Deformity of finger(s)	0.000	0.985	0.015
E80.4 Gilbert's syndrome	0.000	0.985	0.015
L28.2 Other prurigo	0.015	0.985	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.985	0.015
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.985	0.015
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.985	0.015
L25.9 Unspecified contact dermatitis, unspecified cause	0.015	0.985	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.015	0.985	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations