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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62174474
log Bayes Factor = 0.612176
Chromosome 2   position 188,180,409  (GRCh37) Explore rs62174474 on Ensembl!
Variant rs62174474 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I50 Heart failure
0.000 0.292 0.708
I45.1 Other and unspecified right bundle-branch block
0.000 0.294 0.706
I45 Other conduction disorders
0.000 0.298 0.702
I30-I52 Other forms of heart disease
0.000 0.300 0.700
I50.1 Left ventricular failure
0.000 0.309 0.691
I49 Other cardiac arrhythmias
0.000 0.312 0.688
I50.9 Heart failure, unspecified
0.000 0.316 0.684
I49.8 Other specified cardiac arrhythmias
0.000 0.332 0.668
I44 Atrioventricular and left bundle-branch block
0.000 0.357 0.643
I49.9 Cardiac arrhythmia, unspecified
0.000 0.359 0.641
I50.0 Congestive heart failure
0.000 0.372 0.628
I49.0 Ventricular fibrillation and flutter
0.000 0.392 0.608
I51 Complications and ill-defined descriptions of heart disease
0.000 0.397 0.603
I51.8 Other ill-defined heart diseases
0.000 0.404 0.596
I45.5 Other specified heart block
0.000 0.444 0.556
I44.2 Atrioventricular block, complete
0.000 0.448 0.552
I45.2 Bifascicular block
0.000 0.452 0.548
I36 Nonrheumatic tricuspid valve disorders
0.000 0.458 0.542
I44.7 Left bundle-branch block, unspecified
0.000 0.462 0.538
I44.3 Other and unspecified atrioventricular block
0.000 0.470 0.530
I44.1 Atrioventricular block, second degree
0.000 0.474 0.526
I46 Cardiac arrest
0.000 0.481 0.519
I45.6 Preexcitation syndrome
0.000 0.491 0.509
I45.8 Other specified conduction disorders
0.000 0.497 0.503
I45.4 Nonspecific intraventricular block
0.000 0.497 0.503
I45.0 Right fascicular block
0.000 0.497 0.503
I52 Other heart disorders in diseases classified elsewhere
0.000 0.498 0.502
I48 Atrial fibrillation and flutter
0.000 0.498 0.502
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.498 0.502
I41 Myocarditis in diseases classified elsewhere
0.000 0.498 0.502
I40 Acute myocarditis
0.000 0.498 0.502
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.498 0.502
I32 Pericarditis in diseases classified elsewhere
0.000 0.498 0.502
I49.4 Other and unspecified premature depolarisation
0.000 0.503 0.497
I37 Pulmonary valve disorders
0.000 0.505 0.495
I49.2 Junctional premature depolarisation
0.000 0.506 0.493
I49.5 Sick sinus syndrome
0.000 0.529 0.471
I44.6 Other and unspecified fascicular block
0.000 0.539 0.461
I44.5 Left posterior fascicular block
0.000 0.539 0.461
I44.4 Left anterior fascicular block
0.000 0.539 0.461
I45.3 Trifascicular block
0.000 0.554 0.446
I45.9 Conduction disorder, unspecified
0.000 0.555 0.445
I51.4 Myocarditis, unspecified
0.000 0.557 0.443
I51.5 Myocardial degeneration
0.000 0.568 0.432
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.568 0.432
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.568 0.432
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.568 0.432
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.571 0.428
I30 Acute pericarditis
0.000 0.575 0.425
I33 Acute and subacute endocarditis
0.000 0.584 0.416
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.611 0.389
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.611 0.389
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.611 0.389
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.611 0.389
I46.9 Cardiac arrest, unspecified
0.000 0.615 0.385
I49.1 Atrial premature depolarisation
0.000 0.622 0.378
I46.0 Cardiac arrest with successful resuscitation
0.000 0.625 0.375
I51.0 Cardiac septal defect, acquired
0.000 0.627 0.373
I46.1 Sudden cardiac death, so described
0.000 0.628 0.372
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.640 0.360
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.640 0.360
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.640 0.360
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I40.9 Acute myocarditis, unspecified
0.000 0.640 0.360
I40.8 Other acute myocarditis
0.000 0.640 0.360
I40.1 Isolated myocarditis
0.000 0.640 0.360
I40.0 Infective myocarditis
0.000 0.640 0.360
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.640 0.360
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.640 0.360
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.640 0.360
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.640 0.360
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.640 0.360
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.640 0.360
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.640 0.360
I48.4 Atypical atrial flutter
0.000 0.640 0.360
I48.3 Typical atrial flutter
0.000 0.640 0.360
I48.2 Chronic atrial fibrillation
0.000 0.640 0.360
I48.1 Persistent atrial fibrillation
0.000 0.640 0.360
I48.0 Paroxysmal atrial fibrillation
0.000 0.640 0.360
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.640 0.360
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.640 0.360
I38 Endocarditis, valve unspecified
0.000 0.641 0.358
I37.9 Pulmonary valve disorder, unspecified
0.000 0.645 0.355
I37.8 Other pulmonary valve disorders
0.000 0.645 0.355
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.645 0.355
I37.0 Pulmonary valve stenosis
0.000 0.645 0.355
I37.1 Pulmonary valve insufficiency
0.000 0.652 0.348
I51.6 Cardiovascular disease, unspecified
0.000 0.661 0.339
I47 Paroxysmal tachycardia
0.000 0.661 0.339
I31 Other diseases of pericardium
0.000 0.695 0.305
I30.8 Other forms of acute pericarditis
0.000 0.695 0.305
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.695 0.305
I33.9 Acute endocarditis, unspecified
0.000 0.701 0.298
I35 Nonrheumatic aortic valve disorders
0.000 0.705 0.295
I42 Cardiomyopathy
0.000 0.706 0.294
I30.1 Infective pericarditis
0.000 0.716 0.284
I44.0 Atrioventricular block, first degree
0.000 0.724 0.275
I47.2 Ventricular tachycardia
0.000 0.725 0.275
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.737 0.263
I51.9 Heart disease, unspecified
0.000 0.738 0.262
I30.9 Acute pericarditis, unspecified
0.000 0.743 0.257
I51.7 Cardiomegaly
0.000 0.743 0.257
I10 Essential (primary) hypertension
0.000 0.747 0.253
I35.8 Other aortic valve disorders
0.000 0.765 0.235
I10-I15 Hypertensive diseases
0.000 0.766 0.234
Chapter IX Diseases of the circulatory system
0.000 0.780 0.220
I31.8 Other specified diseases of pericardium
0.000 0.781 0.219
I31.2 Haemopericardium, not elsewhere classified
0.000 0.781 0.219
I31.1 Chronic constrictive pericarditis
0.000 0.781 0.219
I31.0 Chronic adhesive pericarditis
0.000 0.781 0.219
I33.0 Acute and subacute infective endocarditis
0.001 0.787 0.212
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.789 0.211
I42.5 Other restrictive cardiomyopathy
0.000 0.789 0.211
I42.4 Endocardial fibroelastosis
0.000 0.789 0.211
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.789 0.211
I42.8 Other cardiomyopathies
0.000 0.789 0.210
I42.2 Other hypertrophic cardiomyopathy
0.000 0.796 0.204
I31.9 Disease of pericardium, unspecified
0.000 0.799 0.200
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.801 0.199
I42.0 Dilated cardiomyopathy
0.000 0.809 0.191
I11 Hypertensive heart disease
0.000 0.812 0.188
I49.3 Ventricular premature depolarisation
0.001 0.813 0.185
I47.0 Reentry ventricular arrhythmia
0.000 0.814 0.185
I42.6 Alcoholic cardiomyopathy
0.000 0.814 0.185
I42.9 Cardiomyopathy, unspecified
0.000 0.815 0.185
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.819 0.181
I34 Nonrheumatic mitral valve disorders
0.000 0.820 0.180
I35.1 Aortic (valve) insufficiency
0.000 0.822 0.178
I15 Secondary hypertension
0.000 0.827 0.173
I13 Hypertensive heart and renal disease
0.000 0.832 0.168
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.834 0.165
I35.9 Aortic valve disorder, unspecified
0.000 0.838 0.162
I00-I02 Acute rheumatic fever
0.000 0.842 0.158
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.844 0.155
I99 Other and unspecified disorders of circulatory system
0.000 0.854 0.146
I95 Hypotension
0.000 0.857 0.143
I05-I09 Chronic rheumatic heart diseases
0.000 0.859 0.141
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.865 0.135
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.865 0.135
I35.0 Aortic (valve) stenosis
0.000 0.865 0.135
I12 Hypertensive renal disease
0.000 0.869 0.131
I15.1 Hypertension secondary to other renal disorders
0.000 0.870 0.130
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.871 0.129
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.871 0.129
I95.1 Orthostatic hypotension
0.000 0.872 0.128
I07 Rheumatic tricuspid valve diseases
0.000 0.873 0.127
I15.9 Seconday hypertension, unspecified
0.000 0.876 0.124
I15.8 Other secondary hypertension
0.000 0.876 0.124
I15.2 Hypertension secondary to endocrine disorders
0.000 0.876 0.124
I15.0 Renovascular hypertension
0.000 0.876 0.124
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.879 0.121
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.879 0.121
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.879 0.121
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.879 0.121
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.880 0.120
I07.1 Tricuspid insufficiency
0.000 0.883 0.117
I02 Rheumatic chorea
0.000 0.886 0.113
I01 Rheumatic fever with heart involvement
0.000 0.886 0.113
I00 Rheumatic fever without mention of heart involvement
0.000 0.886 0.113
I34.1 Mitral (valve) prolapse
0.000 0.889 0.111
I95.8 Other hypotension
0.000 0.897 0.103
I95.0 Idiopathic hypotension
0.000 0.897 0.103
I95.2 Hypotension due to drugs
0.000 0.898 0.102
I09 Other rheumatic heart diseases
0.000 0.899 0.101
I06 Rheumatic aortic valve diseases
0.000 0.899 0.101
I97.1 Other functional disturbances following cardiac surgery
0.000 0.900 0.100
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.901 0.098
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.903 0.097
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.903 0.097
I97.0 Postcardiotomy syndrome
0.000 0.903 0.097
I07.9 Tricuspid valve disease, unspecified
0.000 0.909 0.091
I07.8 Other tricuspid valve diseases
0.000 0.909 0.091
I07.2 Tricuspid stenosis with insufficiency
0.000 0.909 0.091
I07.0 Tricuspid stenosis
0.000 0.909 0.091
I34.2 Nonrheumatic mitral (valve) stenosis
0.001 0.912 0.087
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.914 0.086
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.914 0.086
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.914 0.086
I98.0 Cardiovascular syphilis
0.000 0.914 0.086
I12.9 Hypertensive renal disease without renal failure
0.000 0.915 0.085
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.917 0.083
I05 Rheumatic mitral valve diseases
0.000 0.918 0.082
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.918 0.081
I01.8 Other acute rheumatic heart disease
0.000 0.918 0.081
I01.2 Acute rheumatic myocarditis
0.000 0.918 0.081
I01.1 Acute rheumatic endocarditis
0.000 0.918 0.081
I01.0 Acute rheumatic pericarditis
0.000 0.918 0.081
I02.9 Rheumatic chorea without heart involvement
0.000 0.918 0.081
I02.0 Rheumatic chorea with heart involvement
0.000 0.918 0.081
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.923 0.076
I95.9 Hypotension, unspecified
0.000 0.927 0.073
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.927 0.073
I06.8 Other rheumatic aortic valve diseases
0.000 0.927 0.073
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.927 0.073
I06.1 Rheumatic aortic insufficiency
0.000 0.927 0.073
I06.0 Rheumatic aortic stenosis
0.000 0.927 0.073
I09.9 Rheumatic heart disease, unspecified
0.000 0.927 0.073
I09.8 Other specified rheumatic heart diseases
0.000 0.927 0.073
I09.2 Chronic rheumatic pericarditis
0.000 0.927 0.073
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.927 0.073
I09.0 Rheumatic myocarditis
0.000 0.927 0.073
I12.0 Hypertensive renal disease with renal failure
0.000 0.927 0.073
I31.3 Pericardial effusion (noninflammatory)
0.001 0.928 0.071
I05.9 Mitral valve disease, unspecified
0.000 0.938 0.061
I28 Other diseases of pulmonary vessels
0.000 0.940 0.059
I05.8 Other mitral valve diseases
0.000 0.941 0.059
I05.1 Rheumatic mitral insufficiency
0.000 0.941 0.059
I05.0 Mitral stenosis
0.000 0.950 0.050
I20-I25 Ischaemic heart diseases
0.000 0.951 0.049
I05.2 Mitral stenosis with insufficiency
0.000 0.953 0.047
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.956 0.044
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.957 0.043
I28.8 Other specified diseases of pulmonary vessels
0.000 0.957 0.043
I28.1 Aneurysm of pulmonary artery
0.000 0.957 0.043
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.957 0.043
E87.5 Hyperkalaemia
0.000 0.957 0.043
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.959 0.041
E87.7 Fluid overload
0.000 0.960 0.040
I22 Subsequent myocardial infarction
0.000 0.960 0.040
E83.5 Disorders of calcium metabolism
0.000 0.960 0.040
E70-E90 Metabolic disorders
0.000 0.962 0.038
E83 Disorders of mineral metabolism
0.000 0.962 0.038
I26 Pulmonary embolism
0.000 0.962 0.037
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.963 0.037
I08 Multiple valve diseases
0.000 0.963 0.037
E89.0 Postprocedural hypothyroidism
0.000 0.963 0.037
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.964 0.036
E87.6 Hypokalaemia
0.000 0.964 0.036
I60-I69 Cerebrovascular diseases
0.000 0.964 0.036
E87.3 Alkalosis
0.000 0.964 0.036
I20 Angina pectoris
0.000 0.964 0.036
I23 Certain current complications following acute myocardial infarction
0.000 0.965 0.035
I20.8 Other forms of angina pectoris
0.000 0.965 0.035
E87.0 Hyperosmolality and hypernatraemia
0.000 0.965 0.035
I72 Other aneurysm
0.000 0.967 0.033
I27 Other pulmonary heart diseases
0.000 0.968 0.032
E87.4 Mixed disorder of acid-base balance
0.000 0.968 0.032
I24 Other acute ischaemic heart diseases
0.000 0.968 0.032
I22.8 Subsequent myocardial infarction of other sites
0.000 0.969 0.031
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.969 0.031
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.969 0.031
E83.3 Disorders of phosphorus metabolism
0.000 0.970 0.030
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.970 0.030
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.970 0.030
I47.1 Supraventricular tachycardia
0.001 0.970 0.029
I77 Other disorders of arteries and arterioles
0.000 0.970 0.030
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.970 0.030
E87.2 Acidosis
0.000 0.970 0.030
E89.3 Postprocedural hypopituitarism
0.000 0.971 0.029
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.971 0.029
I34.0 Mitral (valve) insufficiency
0.000 0.972 0.028
I74 Arterial embolism and thrombosis
0.000 0.972 0.028
E84 Cystic fibrosis
0.000 0.973 0.027
E79 Disorders of purine and pyrimidine metabolism
0.000 0.973 0.027
E77 Disorders of glycoprotein metabolism
0.000 0.973 0.027
E76 Disorders of glycosaminoglycan metabolism
0.000 0.973 0.027
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.973 0.027
E74 Other disorders of carbohydrate metabolism
0.000 0.973 0.027
E72 Other disorders of amino-acid metabolism
0.000 0.973 0.027
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.973 0.027
E70 Disorders of aromatic amino-acid metabolism
0.000 0.973 0.027
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.973 0.027
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.973 0.027
E83.8 Other disorders of mineral metabolism
0.000 0.973 0.027
E83.2 Disorders of zinc metabolism
0.000 0.973 0.027
E83.0 Disorders of copper metabolism
0.000 0.973 0.027
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.973 0.027
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.973 0.027
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.973 0.027
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.973 0.027
E89.5 Postprocedural testicular hypofunction
0.000 0.973 0.027
E89.4 Postprocedural ovarian failure
0.000 0.973 0.027
E89.2 Postprocedural hypoparathyroidism
0.000 0.973 0.027
E89.1 Postprocedural hypoinsulinaemia
0.000 0.973 0.027
H40.1 Primary open-angle glaucoma
0.000 0.973 0.027
I08.9 Multiple valve disease, unspecified
0.000 0.973 0.026
I70 Atherosclerosis
0.000 0.973 0.026
I72.8 Aneurysm of other specified arteries
0.000 0.974 0.026
I72.4 Aneurysm of artery of lower extremity
0.000 0.974 0.026
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.974 0.026
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.974 0.026
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.974 0.026
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.974 0.026
E85 Amyloidosis
0.000 0.974 0.026
I23.8 Other current complications following acute myocardial infarction
0.000 0.974 0.025
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.974 0.025
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.974 0.025
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.974 0.025
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.974 0.025
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.974 0.025
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.974 0.025
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.974 0.025
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.975 0.025
E88 Other metabolic disorders
0.000 0.975 0.025
H40 Glaucoma
0.000 0.975 0.025
E86 Volume depletion
0.000 0.975 0.025
I61 Intracerebral haemorrhage
0.000 0.975 0.025
H40.0 Glaucoma suspect
0.000 0.975 0.025
I08.8 Other multiple valve diseases
0.000 0.975 0.024
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.976 0.024
I72.9 Aneurysm of unspecified site
0.000 0.976 0.024
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.976 0.024
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.976 0.024
I72.2 Aneurysm of renal artery
0.000 0.976 0.024
I72.1 Aneurysm of artery of upper extremity
0.000 0.976 0.024
I72.0 Aneurysm of carotid artery
0.000 0.976 0.024
I27.8 Other specified pulmonary heart diseases
0.000 0.977 0.023
I27.1 Kyphoscoliotic heart disease
0.000 0.977 0.023
I20.0 Unstable angina
0.000 0.977 0.023
E73 Lactose intolerance
0.000 0.977 0.023
I24.1 Dressler's syndrome
0.000 0.977 0.023
I72.3 Aneurysm of iliac artery
0.000 0.977 0.022
I77.8 Other specified disorders of arteries and arterioles
0.000 0.977 0.022
E83.4 Disorders of magnesium metabolism
0.000 0.978 0.022
H40.9 Glaucoma, unspecified
0.000 0.978 0.022
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.978 0.022
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.978 0.022
I77.5 Necrosis of artery
0.000 0.978 0.021
I77.4 Coeliac artery compression syndrome
0.000 0.978 0.021
I77.3 Arterial fibromuscular dysplasia
0.000 0.978 0.021
I77.2 Rupture of artery
0.000 0.978 0.021
I77.0 Arteriovenous fistula, acquired
0.000 0.978 0.021
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.978 0.022
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.978 0.021
I79.1 Aortitis in diseases classified elsewhere
0.000 0.978 0.021
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.978 0.021
I27.2 Other secondary pulmonary hypertension
0.000 0.979 0.021
E83.1 Disorders of iron metabolism
0.000 0.979 0.021
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.979 0.021
I63 Cerebral infarction
0.000 0.979 0.021
I77.6 Arteritis, unspecified
0.000 0.980 0.020
I74.8 Embolism and thrombosis of other arteries
0.000 0.980 0.020
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.980 0.020
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.980 0.020
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.980 0.020
I08.0 Disorders of both mitral and aortic valves
0.000 0.980 0.020
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.980 0.020
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.980 0.020
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.980 0.020
E70.3 Albinism
0.000 0.980 0.020
E70.2 Disorders of tyrosine metabolism
0.000 0.980 0.020
E70.1 Other hyperphenylalaninaemias
0.000 0.980 0.020
E70.0 Classical phenylketonuria
0.000 0.980 0.020
E71.3 Disorders of fatty-acid metabolism
0.000 0.980 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.980 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.980 0.020
E71.0 Maple-syrup-urine disease
0.000 0.980 0.020
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.980 0.020
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.980 0.020
E72.5 Disorders of glycine metabolism
0.000 0.980 0.020
E72.4 Disorders of ornithine metabolism
0.000 0.980 0.020
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.980 0.020
E72.2 Disorders of urea cycle metabolism
0.000 0.980 0.020
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.980 0.020
E72.0 Disorders of amino-acid transport
0.000 0.980 0.020
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.980 0.020
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.980 0.020
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.980 0.020
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.980 0.020
E74.2 Disorders of galactose metabolism
0.000 0.980 0.020
E74.1 Disorders of fructose metabolism
0.000 0.980 0.020
E74.0 Glycogen storage disease
0.000 0.980 0.020
E75.6 Lipid storage disorder, unspecified
0.000 0.980 0.020
E75.5 Other lipid storage disorders
0.000 0.980 0.020
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.980 0.020
E75.3 Sphingolipidosis, unspecified
0.000 0.980 0.020
E75.2 Other sphingolipidosis
0.000 0.980 0.020
E75.1 Other gangliosidosis
0.000 0.980 0.020
E75.0 GM2 gangliosidosis
0.000 0.980 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.980 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.980 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.980 0.020
E76.2 Other mucopolysaccharidoses
0.000 0.980 0.020
E76.1 Mucopolysaccharidosis, type II
0.000 0.980 0.020
E76.0 Mucopolysaccharidosis, type I
0.000 0.980 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.980 0.020
E77.8 Other disorders of glycoprotein metabolism
0.000 0.980 0.020
E77.1 Defects in glycoprotein degradation
0.000 0.980 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.980 0.020
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.980 0.020
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.980 0.020
E79.1 Lesch-Nyhan syndrome
0.000 0.980 0.020
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.980 0.020
E84.9 Cystic fibrosis, unspecified
0.000 0.980 0.020
E84.8 Cystic fibrosis with other manifestations
0.000 0.980 0.020
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.980 0.020
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.980 0.020
I62 Other nontraumatic intracranial haemorrhage
0.000 0.980 0.020
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.981 0.019
I20.1 Angina pectoris with documented spasm
0.000 0.981 0.019
I70.9 Generalised and unspecified atherosclerosis
0.000 0.981 0.019
I70.8 Atherosclerosis of other arteries
0.000 0.981 0.019
I70.1 Atherosclerosis of renal artery
0.000 0.981 0.019
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.981 0.019
I78 Diseases of capillaries
0.000 0.981 0.019
I27.9 Pulmonary heart disease, unspecified
0.001 0.981 0.019
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.981 0.019
E80.6 Other disorders of bilirubin metabolism
0.000 0.981 0.019
E80.5 Crigler-Najjar syndrome
0.000 0.981 0.019
E80.3 Defects of catalase and peroxydase
0.000 0.981 0.019
E80.2 Other porphyria
0.000 0.981 0.019
E80.1 Porphyria cutanea tarda
0.000 0.981 0.019
E80.0 Hereditary erythropoietic porphyria
0.000 0.981 0.019
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.981 0.019
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.981 0.019
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.981 0.019
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.981 0.019
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.981 0.019
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.981 0.019
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.981 0.019
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.981 0.019
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.981 0.019
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.981 0.019
I68.0 Cerebral amyloid angiopathy
0.000 0.981 0.019
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.981 0.019
H40.8 Other glaucoma
0.000 0.981 0.019
E85.8 Other amyloidosis
0.000 0.981 0.018
E85.4 Organ-limited amyloidosis
0.000 0.981 0.018
E85.3 Secondary systemic amyloidosis
0.000 0.981 0.018
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.981 0.018
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.981 0.018
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.981 0.018
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.981 0.019
I69 Sequelae of cerebrovascular disease
0.000 0.981 0.019
I63.8 Other cerebral infarction
0.000 0.982 0.018
I60 Subarachnoid haemorrhage
0.000 0.982 0.018
E88.9 Metabolic disorder, unspecified
0.000 0.982 0.018
E88.8 Other specified metabolic disorders
0.000 0.982 0.018
E88.3 Tumour lysis syndrome
0.000 0.982 0.018
E88.2 Lipomatosis, not elsewhere classified
0.000 0.982 0.018
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.982 0.018
H40.6 Glaucoma secondary to drugs
0.000 0.982 0.018
H40.4 Glaucoma secondary to eye inflammation
0.000 0.982 0.018
H40.3 Glaucoma secondary to eye trauma
0.000 0.982 0.018
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.982 0.018
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.982 0.018
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.982 0.018
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.982 0.018
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.982 0.018
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.982 0.018
I70.0 Atherosclerosis of aorta
0.000 0.982 0.018
E80.4 Gilbert's syndrome
0.000 0.982 0.018
H40.5 Glaucoma secondary to other eye disorders
0.000 0.982 0.018
I77.1 Stricture of artery
0.000 0.982 0.018
I61.8 Other intracerebral haemorrhage
0.000 0.982 0.018
I74.5 Embolism and thrombosis of iliac artery
0.000 0.982 0.018
I24.8 Other forms of acute ischaemic heart disease
0.000 0.982 0.017
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.982 0.017
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.983 0.017
E85.9 Amyloidosis, unspecified
0.000 0.983 0.017
N13 Obstructive and reflux uropathy
0.000 0.983 0.017
E73.8 Other lactose intolerance
0.000 0.983 0.017
E73.1 Secondary lactase deficiency
0.000 0.983 0.017
E73.0 Congenital lactase deficiency
0.000 0.983 0.017
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.983 0.016
I71 Aortic aneurysm and dissection
0.000 0.984 0.016
I65.2 Occlusion and stenosis of carotid artery
0.000 0.984 0.016
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.984 0.016
N13.8 Other obstructive and reflux uropathy
0.000 0.984 0.016
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.984 0.016
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.984 0.016
I65.1 Occlusion and stenosis of basilar artery
0.000 0.984 0.016
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.984 0.016
H40.2 Primary angle-closure glaucoma
0.000 0.984 0.016
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.985 0.015
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.985 0.015
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.985 0.015
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.985 0.015
I62.1 Nontraumatic extradural haemorrhage
0.000 0.985 0.014
N13.3 Other and unspecified hydronephrosis
0.000 0.986 0.014
N13.4 Hydroureter
0.000 0.986 0.014
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.986 0.014
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.986 0.014
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.986 0.014
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.986 0.014
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.986 0.014
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.986 0.014
I78.9 Disease of capillaries, unspecified
0.000 0.986 0.014
I73 Other peripheral vascular diseases
0.000 0.986 0.014
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.986 0.014
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.986 0.013
I69.3 Sequelae of cerebral infarction
0.000 0.986 0.014
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.986 0.013
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.986 0.013
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.986 0.013
I60.8 Other subarachnoid haemorrhage
0.000 0.987 0.013
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.987 0.013
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.987 0.013
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.987 0.013
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.987 0.013
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.987 0.013
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.987 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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