TreeWAS – Variant ID: rs62401365

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.779	0.221
E10 Insulin-dependent diabetes mellitus	0.000	0.813	0.187
E10.9 Without complications	0.000	0.816	0.184
E10.6 With other specified complications	0.000	0.830	0.170
E10.5 With peripheral circulatory complications	0.000	0.836	0.164
E10.4 With neurological complications	0.000	0.838	0.162
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.840	0.160
K90.3 Pancreatic steatorrhoea	0.000	0.841	0.159
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.841	0.159
K90.1 Tropical sprue	0.000	0.841	0.159
E10.1 With ketoacidosis	0.000	0.841	0.159
E10.3 With ophthalmic complications	0.000	0.845	0.155
E10.8 With unspecified complications	0.000	0.848	0.152
K90.8 Other intestinal malabsorption	0.000	0.849	0.151
E10.0 With coma	0.000	0.865	0.135
E10.7 With multiple complications	0.000	0.865	0.134
E83 Disorders of mineral metabolism	0.000	0.870	0.130
E10.2 With renal complications	0.000	0.873	0.127
E10-E14 Diabetes mellitus	0.000	0.879	0.121
E13 Other specified diabetes mellitus	0.000	0.900	0.100
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.906	0.093
E83.8 Other disorders of mineral metabolism	0.000	0.906	0.093
E83.2 Disorders of zinc metabolism	0.000	0.906	0.093
E83.0 Disorders of copper metabolism	0.000	0.906	0.093
E12 Malnutrition-related diabetes mellitus	0.000	0.913	0.087
E13.9 Without complications	0.000	0.914	0.086
E70-E90 Metabolic disorders	0.000	0.918	0.082
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.919	0.081
E88 Other metabolic disorders	0.000	0.920	0.080
E11 Non-insulin-dependent diabetes mellitus	0.000	0.920	0.080
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.924	0.076
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.924	0.076
E13.8 With unspecified complications	0.000	0.928	0.072
E13.7 With multiple complications	0.000	0.928	0.072
E13.6 With other specified complications	0.000	0.928	0.072
E13.5 With peripheral circulatory complications	0.000	0.928	0.072
E13.4 With neurological complications	0.000	0.928	0.072
E13.2 With renal complications	0.000	0.928	0.072
E13.1 With ketoacidosis	0.000	0.928	0.072
E13.0 With coma	0.000	0.928	0.072
E16 Other disorders of pancreatic internal secretion	0.000	0.928	0.072
E16.2 Hypoglycaemia, unspecified	0.000	0.930	0.070
E13.3 With ophthalmic complications	0.000	0.930	0.070
E11.2 With renal complications	0.000	0.932	0.068
E14 Unspecified diabetes mellitus	0.000	0.933	0.067
K90.9 Intestinal malabsorption, unspecified	0.001	0.933	0.066
E40-E46 Malnutrition	0.000	0.935	0.065
E11.0 With coma	0.000	0.935	0.065
E11.4 With neurological complications	0.000	0.936	0.064
E85 Amyloidosis	0.000	0.936	0.064
E88.8 Other specified metabolic disorders	0.000	0.936	0.064
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.936	0.064
E14.3 With ophthalmic complications	0.000	0.937	0.063
E88.2 Lipomatosis, not elsewhere classified	0.000	0.937	0.063
E12.9 Without complications	0.000	0.937	0.063
E12.8 With unspecified complications	0.000	0.937	0.063
E12.7 With multiple complications	0.000	0.937	0.063
E12.6 With other specified complications	0.000	0.937	0.063
E12.5 With peripheral circulatory complications	0.000	0.937	0.063
E12.4 With neurological complications	0.000	0.937	0.063
E12.3 With ophthalmic complications	0.000	0.937	0.063
E12.2 With renal complications	0.000	0.937	0.063
E12.1 With ketoacidosis	0.000	0.937	0.063
E12.0 With coma	0.000	0.937	0.063
E83.3 Disorders of phosphorus metabolism	0.000	0.938	0.062
E88.3 Tumour lysis syndrome	0.000	0.939	0.061
E11.1 With ketoacidosis	0.000	0.939	0.061
E11.5 With peripheral circulatory complications	0.000	0.940	0.060
E11.8 With unspecified complications	0.000	0.941	0.059
E84 Cystic fibrosis	0.000	0.941	0.059
E77 Disorders of glycoprotein metabolism	0.000	0.941	0.059
E76 Disorders of glycosaminoglycan metabolism	0.000	0.941	0.059
E72 Other disorders of amino-acid metabolism	0.000	0.941	0.059
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.941	0.059
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.941	0.059
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.941	0.059
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.942	0.058
E11.7 With multiple complications	0.000	0.943	0.057
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.943	0.057
E70 Disorders of aromatic amino-acid metabolism	0.000	0.945	0.055
E15 Nondiabetic hypoglycaemic coma	0.000	0.945	0.054
E88.9 Metabolic disorder, unspecified	0.000	0.946	0.054
E46 Unspecified protein-energy malnutrition	0.000	0.946	0.054
E79 Disorders of purine and pyrimidine metabolism	0.000	0.947	0.052
E11.6 With other specified complications	0.000	0.947	0.053
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.948	0.052
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.948	0.052
E16.4 Abnormal secretion of gastrin	0.000	0.948	0.052
E16.3 Increased secretion of glucagon	0.000	0.948	0.052
E85.9 Amyloidosis, unspecified	0.000	0.948	0.052
E14.5 With peripheral circulatory complications	0.000	0.951	0.049
E14.7 With multiple complications	0.000	0.951	0.048
E14.2 Withrenal complications	0.000	0.951	0.048
E14.0 With coma	0.000	0.951	0.048
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.953	0.047
E45 Retarded development following protein-energy malnutrition	0.000	0.953	0.047
E43 Unspecified severe protein-energy malnutrition	0.000	0.953	0.047
E42 Marasmic kwashiorkor	0.000	0.953	0.047
E41 Nutritional marasmus	0.000	0.953	0.047
E40 Kwashiorkor	0.000	0.953	0.047
E85.4 Organ-limited amyloidosis	0.000	0.953	0.047
E85.8 Other amyloidosis	0.000	0.954	0.046
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.954	0.046
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.954	0.046
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.954	0.046
E14.6 With other specified complications	0.000	0.954	0.046
E73 Lactose intolerance	0.000	0.955	0.045
E65-E68 Obesity and other hyperalimentation	0.000	0.955	0.045
E14.4 With neurological complications	0.000	0.956	0.044
E14.1 With ketoacidosis	0.000	0.956	0.044
E85.3 Secondary systemic amyloidosis	0.000	0.956	0.044
E83.4 Disorders of magnesium metabolism	0.000	0.956	0.044
E80.4 Gilbert's syndrome	0.000	0.956	0.044
E74 Other disorders of carbohydrate metabolism	0.000	0.957	0.043
E71.3 Disorders of fatty-acid metabolism	0.000	0.957	0.043
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.957	0.043
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.957	0.043
E71.0 Maple-syrup-urine disease	0.000	0.957	0.043
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.957	0.043
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.957	0.043
E72.5 Disorders of glycine metabolism	0.000	0.957	0.043
E72.4 Disorders of ornithine metabolism	0.000	0.957	0.043
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.957	0.043
E72.2 Disorders of urea cycle metabolism	0.000	0.957	0.043
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.957	0.043
E72.0 Disorders of amino-acid transport	0.000	0.957	0.043
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.957	0.043
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.957	0.043
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.957	0.043
E76.2 Other mucopolysaccharidoses	0.000	0.957	0.043
E76.1 Mucopolysaccharidosis, type II	0.000	0.957	0.043
E76.0 Mucopolysaccharidosis, type I	0.000	0.957	0.043
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.957	0.043
E77.8 Other disorders of glycoprotein metabolism	0.000	0.957	0.043
E77.1 Defects in glycoprotein degradation	0.000	0.957	0.043
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.957	0.043
E84.9 Cystic fibrosis, unspecified	0.000	0.957	0.043
E84.8 Cystic fibrosis with other manifestations	0.000	0.957	0.043
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.957	0.043
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.957	0.043
R31 Unspecified haematuria	0.043	0.957	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.957	0.042
E80.5 Crigler-Najjar syndrome	0.000	0.957	0.042
E80.3 Defects of catalase and peroxydase	0.000	0.957	0.042
E80.1 Porphyria cutanea tarda	0.000	0.957	0.042
E80.0 Hereditary erythropoietic porphyria	0.000	0.957	0.042
E80.2 Other porphyria	0.000	0.958	0.042
E80.6 Other disorders of bilirubin metabolism	0.000	0.959	0.041
E75.6 Lipid storage disorder, unspecified	0.000	0.959	0.041
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.959	0.041
E75.3 Sphingolipidosis, unspecified	0.000	0.959	0.041
E75.2 Other sphingolipidosis	0.000	0.959	0.041
E75.1 Other gangliosidosis	0.000	0.959	0.041
E75.0 GM2 gangliosidosis	0.000	0.959	0.041
E11.3 With ophthalmic complications	0.000	0.960	0.040
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.960	0.040
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.960	0.040
E70.2 Disorders of tyrosine metabolism	0.000	0.960	0.040
E70.1 Other hyperphenylalaninaemias	0.000	0.960	0.040
E70.0 Classical phenylketonuria	0.000	0.960	0.040
E75.5 Other lipid storage disorders	0.000	0.961	0.039
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.962	0.038
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.962	0.038
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.962	0.038
E79.1 Lesch-Nyhan syndrome	0.000	0.962	0.038
E16.1 Other hypoglycaemia	0.000	0.962	0.037
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.963	0.037
E70.3 Albinism	0.000	0.964	0.036
E65 Localised adiposity	0.000	0.964	0.036
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.965	0.035
E14.8 With unspecified complications	0.000	0.965	0.035
E44.1 Mild protein-energy malnutrition	0.000	0.966	0.034
E44.0 Moderate protein-energy malnutrition	0.000	0.966	0.034
E73.8 Other lactose intolerance	0.000	0.967	0.032
E73.1 Secondary lactase deficiency	0.000	0.967	0.032
E73.0 Congenital lactase deficiency	0.000	0.967	0.032
E67 Other hyperalimentation	0.000	0.968	0.032
E68 Sequelae of hyperalimentation	0.000	0.968	0.032
E87.0 Hyperosmolality and hypernatraemia	0.000	0.968	0.032
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.968	0.032
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.969	0.031
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.969	0.031
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.969	0.031
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.969	0.031
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.969	0.031
E74.2 Disorders of galactose metabolism	0.000	0.969	0.031
E74.1 Disorders of fructose metabolism	0.000	0.969	0.031
E50-E64 Other nutritional deficiencies	0.000	0.969	0.031
E87.5 Hyperkalaemia	0.000	0.970	0.030
E89.4 Postprocedural ovarian failure	0.000	0.971	0.029
E87.3 Alkalosis	0.000	0.971	0.029
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.971	0.029
E74.0 Glycogen storage disease	0.000	0.972	0.028
E89.2 Postprocedural hypoparathyroidism	0.000	0.972	0.028
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.972	0.028
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.972	0.028
E89.5 Postprocedural testicular hypofunction	0.000	0.972	0.028
E89.1 Postprocedural hypoinsulinaemia	0.000	0.972	0.028
E87.7 Fluid overload	0.000	0.974	0.026
E87.4 Mixed disorder of acid-base balance	0.000	0.974	0.025
M25.57 Pain in joint (Ankle and foot)	0.000	0.974	0.026
E00-E07 Disorders of thyroid gland	0.000	0.976	0.024
E67.8 Other specified hyperalimentation	0.000	0.976	0.023
E67.3 Hypervitaminosis D	0.000	0.976	0.023
E67.2 Megavitamin-B6 syndrome	0.000	0.976	0.023
E67.1 Hypercarotenaemia	0.000	0.976	0.023
E67.0 Hypervitaminosis A	0.000	0.976	0.023
M25.5 Pain in joint	0.000	0.977	0.023
E78.2 Mixed hyperlipidaemia	0.000	0.977	0.023
E78.4 Other hyperlipidaemia	0.000	0.977	0.023
E78.3 Hyperchylomicronaemia	0.000	0.977	0.023
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.978	0.022
E63 Other nutritional deficiencies	0.000	0.978	0.022
E50 Vitamin A deficiency	0.000	0.978	0.022
E60 Dietary zinc deficiency	0.000	0.978	0.022
E59 Dietary selenium deficiency	0.000	0.978	0.022
E54 Ascorbic acid deficiency	0.000	0.978	0.022
E52 Niacin deficiency [pellagra]	0.000	0.978	0.022
E78.1 Pure hyperglyceridaemia	0.000	0.978	0.022
E58 Dietary calcium deficiency	0.000	0.978	0.022
E53 Deficiency of other B group vitamins	0.000	0.978	0.022
E78.6 Lipoprotein deficiency	0.000	0.978	0.022
E56 Other vitamin deficiencies	0.000	0.978	0.021
G31.8 Other specified degenerative diseases of nervous system	0.000	0.979	0.021
E51 Thiamine deficiency	0.000	0.979	0.021
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.979	0.021
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.979	0.020
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.979	0.021
E83.5 Disorders of calcium metabolism	0.000	0.980	0.020
E89.0 Postprocedural hypothyroidism	0.000	0.980	0.020
M25.58 Pain in joint (Other)	0.000	0.981	0.019
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.981	0.019
M25.52 Pain in joint (Upper arm)	0.000	0.981	0.019
E55 Vitamin D deficiency	0.000	0.981	0.019
G31.0 Circumscribed brain atrophy	0.000	0.981	0.019
G30 Alzheimer's disease	0.000	0.981	0.019
M25.51 Pain in joint (Shoulder region)	0.000	0.981	0.019
E87.2 Acidosis	0.000	0.981	0.019
E73.9 Lactose intolerance, unspecified	0.001	0.982	0.018
G30-G32 Other degenerative diseases of the nervous system	0.000	0.982	0.018
G30.9 Alzheimer's disease, unspecified	0.000	0.982	0.018
E07 Other disorders of thyroid	0.000	0.983	0.017
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.983	0.017
E00 Congenital iodine-deficiency syndrome	0.000	0.983	0.017
G30.0 Alzheimer's disease with early onset	0.000	0.983	0.017
E53.9 Vitamin B deficiency, unspecified	0.000	0.983	0.017
M25.54 Pain in joint (Hand)	0.000	0.983	0.017
M25.53 Pain in joint (Forearm)	0.000	0.983	0.017
E06 Thyroiditis	0.000	0.984	0.016
E50.9 Vitamin A deficiency, unspecified	0.000	0.984	0.016
E50.8 Other manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.984	0.016
E50.5 Vitamin A deficiency with night blindness	0.000	0.984	0.016
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.984	0.016
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.984	0.016
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.984	0.016
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.984	0.016
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.984	0.016
E63.9 Nutritional deficiency, unspecified	0.000	0.984	0.016
E63.8 Other specified nutritional deficiencies	0.000	0.984	0.016
E63.1 Imbalance of constituents of food intake	0.000	0.984	0.016
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.984	0.016
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.984	0.016
E64.8 Sequelae of other nutritional deficiencies	0.000	0.984	0.016
E64.3 Sequelae of rickets	0.000	0.984	0.016
E64.2 Sequelae of vitamin C deficiency	0.000	0.984	0.016
E64.1 Sequelae of vitamin A deficiency	0.000	0.984	0.016
E64.0 Sequelae of protein-energy malnutrition	0.000	0.984	0.016
E04 Other non-toxic goitre	0.000	0.984	0.016
E53.1 Pyridoxine deficiency	0.000	0.984	0.016
E53.0 Riboflavin deficiency	0.000	0.984	0.016
E56.9 Vitamin deficiency, unspecified	0.000	0.984	0.015
E56.8 Deficiency of other vitamins	0.000	0.984	0.015
E56.0 Deficiency of vitamin E	0.000	0.984	0.015
E51.9 Thiamine deficiency, unspecified	0.000	0.984	0.015
E51.8 Other manifestations of thiamine deficiency	0.000	0.984	0.015
E51.1 Beriberi	0.000	0.984	0.015
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.985	0.015
E56.1 Deficiency of vitamin K	0.000	0.985	0.015
G30.8 Other Alzheimer's disease	0.000	0.985	0.015
K90-K93 Other diseases of the digestive system	0.000	0.985	0.015
E51.2 Wernicke's encephalopathy	0.000	0.986	0.014
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.986	0.014
E89.3 Postprocedural hypopituitarism	0.000	0.986	0.014
E55.0 Rickets, active	0.000	0.986	0.014
G30.1 Alzheimer's disease with late onset	0.000	0.986	0.014
E04.9 Non-toxic goitre, unspecified	0.000	0.986	0.014
E53.8 Deficiency of other specified B group vitamins	0.000	0.986	0.014
E07.9 Disorder of thyroid, unspecified	0.000	0.987	0.013
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.987	0.013
E07.1 Dyshormogenetic goitre	0.000	0.987	0.013
E07.0 Hypersecretion of calcitonin	0.000	0.987	0.013
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.987	0.012
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.987	0.012
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.987	0.012
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.987	0.012
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.987	0.012
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.987	0.012
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.987	0.012
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.987	0.012
E14.9 Without complications	0.000	0.987	0.012
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.988	0.012
E04.0 Non-toxic diffuse goitre	0.000	0.988	0.012
E07.8 Other specified disorders of thyroid	0.000	0.988	0.012
E06.5 Other chronic thyroiditis	0.000	0.988	0.012
E06.4 Drug-induced thyroiditis	0.000	0.988	0.012
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.988	0.012
E06.1 Subacute thyroiditis	0.000	0.988	0.012
E06.0 Acute thyroiditis	0.000	0.988	0.012
E61 Deficiency of other nutrient elements	0.001	0.988	0.011
E04.8 Other specified non-toxic goitre	0.000	0.988	0.012
G31.2 Degeneration of nervous system due to alcohol	0.000	0.988	0.011
E06.3 Autoimmune thyroiditis	0.000	0.988	0.012
E06.9 Thyroiditis, unspecified	0.000	0.989	0.011
E20-E35 Disorders of other endocrine glands	0.000	0.989	0.011
M25.59 Pain in joint (Site unspecified)	0.000	0.989	0.011
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.989	0.011
E03 Other hypothyroidism	0.000	0.989	0.011
G44.2 Tension-type headache	0.011	0.989	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.990	0.010
E86 Volume depletion	0.000	0.990	0.010
E78.8 Other disorders of lipoprotein metabolism	0.001	0.990	0.010
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.990	0.010
E05.8 Other thyrotoxicosis	0.000	0.990	0.010
E04.1 Non-toxic single thyroid nodule	0.000	0.990	0.010
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.990	0.009
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.991	0.009
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.991	0.009
E05.5 Thyroid crisis or storm	0.000	0.991	0.009
E05.4 Thyrotoxicosis factitia	0.000	0.991	0.009
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.991	0.009
E20 Hypoparathyroidism	0.000	0.991	0.009
E27.1 Primary adrenocortical insufficiency	0.000	0.991	0.009
E29 Testicular dysfunction	0.000	0.991	0.009
E61.9 Deficiency of nutrient element, unspecified	0.001	0.991	0.008
E61.8 Deficiency of other specified nutrient elements	0.001	0.991	0.008
E61.7 Deficiency of multiple nutrient elements	0.001	0.991	0.008
E61.6 Vanadium deficiency	0.001	0.991	0.008
E61.5 Molybdenum deficiency	0.001	0.991	0.008
E61.4 Chromium deficiency	0.001	0.991	0.008
E61.3 Manganese deficiency	0.001	0.991	0.008
E61.0 Copper deficiency	0.001	0.991	0.008
E26 Hyperaldosteronism	0.000	0.991	0.009
E03.8 Other specified hypothyroidism	0.000	0.991	0.008
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.992	0.008
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.992	0.008
E32 Diseases of thymus	0.000	0.992	0.008
E31 Polyglandular dysfunction	0.000	0.992	0.008
E30 Disorders of puberty, not elsewhere classified	0.000	0.992	0.008
E25 Adrenogenital disorders	0.000	0.992	0.008
E66 Obesity	0.000	0.992	0.008
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.992	0.008
K93.1 Megacolon in Chagas' disease	0.000	0.992	0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.992	0.008
E03.5 Myxoedema coma	0.000	0.992	0.008
E03.4 Atrophy of thyroid (acquired)	0.000	0.992	0.008
E03.3 Postinfectious hypothyroidism	0.000	0.992	0.008
E03.1 Congenital hypothyroidism without goitre	0.000	0.992	0.008
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.992	0.008
E27 Other disorders of adrenal gland	0.000	0.992	0.008
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.992	0.008
E24 Cushing's syndrome	0.000	0.992	0.007
E20.9 Hypoparathyroidism, unspecified	0.000	0.992	0.007
E04.2 Non-toxic multinodular goitre	0.000	0.992	0.008
E34 Other endocrine disorders	0.000	0.993	0.007
E61.2 Magnesium deficiency	0.001	0.993	0.006
E29.1 Testicular hypofunction	0.000	0.993	0.007
E20.8 Other hypoparathyroidism	0.000	0.993	0.007
E20.1 Pseudohypoparathyroidism	0.000	0.993	0.007
E20.0 Idiopathic hypoparathyroidism	0.000	0.993	0.007
E26.0 Primary hyperaldosteronism	0.000	0.993	0.007
E24.2 Drug-induced Cushing's syndrome	0.000	0.993	0.007
E29.9 Testicular dysfunction, unspecified	0.000	0.993	0.006
E29.8 Other testicular dysfunction	0.000	0.993	0.006
E29.0 Testicular hyperfunction	0.000	0.993	0.006
K22.8 Other specified diseases of oesophagus	0.007	0.993	0.000
E28 Ovarian dysfunction	0.000	0.993	0.006
E26.9 Hyperaldosteronism, unspecified	0.000	0.994	0.006
E26.8 Other hyperaldosteronism	0.000	0.994	0.006
E26.1 Secondary hyperaldosteronism	0.000	0.994	0.006
E23 Hypofunction and other disorders of pituitary gland	0.000	0.994	0.006
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.994	0.006
E87.6 Hypokalaemia	0.000	0.994	0.006
M25.50 Pain in joint (Multiple sites)	0.000	0.994	0.006
E25.9 Adrenogenital disorder, unspecified	0.000	0.994	0.006
E25.8 Other adrenogenital disorders	0.000	0.994	0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.994	0.006
E30.9 Disorder of puberty, unspecified	0.000	0.994	0.006
E30.8 Other disorders of puberty	0.000	0.994	0.006
E30.1 Precocious puberty	0.000	0.994	0.006
E30.0 Delayed puberty	0.000	0.994	0.006
E31.9 Polyglandular dysfunction, unspecified	0.000	0.994	0.006
E31.8 Other polyglandular dysfunction	0.000	0.994	0.006
E31.1 Polyglandular hyperfunction	0.000	0.994	0.006
E31.0 Autoimmune polyglandular failure	0.000	0.994	0.006
E32.9 Disease of thymus, unspecified	0.000	0.994	0.006
E32.8 Other diseases of thymus	0.000	0.994	0.006
E32.1 Abscess of thymus	0.000	0.994	0.006
E32.0 Persistent hyperplasia of thymus	0.000	0.994	0.006
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.994	0.006
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.994	0.006
E66.1 Drug-induced obesity	0.000	0.994	0.006
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.994	0.006
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.006
E27.0 Other adrenocortical overactivity	0.000	0.994	0.006
G44 Other headache syndromes	0.006	0.994	0.000
E23.2 Diabetes insipidus	0.000	0.994	0.006
E24.8 Other Cushing's syndrome	0.000	0.994	0.006
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.994	0.006
E24.3 Ectopic ACTH syndrome	0.000	0.994	0.006
E24.1 Nelson's syndrome	0.000	0.994	0.006
E34.5 Androgen resistance syndrome	0.000	0.994	0.005
E34.4 Constitutional tall stature	0.000	0.994	0.005
E34.3 Short stature, not elsewhere classified	0.000	0.994	0.005
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.994	0.005
E34.1 Other hypersecretion of intestinal hormones	0.000	0.994	0.005
E34.0 Carcinoid syndrome	0.000	0.995	0.005
E66.0 Obesity due to excess calories	0.000	0.995	0.005
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.995	0.005
G44.8 Other specified headache syndromes	0.005	0.995	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.995	0.005
E34.8 Other specified endocrine disorders	0.000	0.995	0.005
E34.9 Endocrine disorder, unspecified	0.000	0.995	0.005
G54.9 Nerve root and plexus disorder, unspecified	0.005	0.995	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.995	0.005
E28.8 Other ovarian dysfunction	0.000	0.995	0.005
E28.1 Androgen excess	0.000	0.995	0.005
E28.0 Oestrogen excess	0.000	0.995	0.005
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.995	0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.995	0.005
E23.1 Drug-induced hypopituitarism	0.000	0.995	0.005
E28.2 Polycystic ovarian syndrome	0.000	0.995	0.005
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.995	0.005
E23.7 Disorder of pituitary gland, unspecified	0.000	0.995	0.004
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
E27.2 Addisonian crisis	0.000	0.995	0.004
G44.0 Cluster headache syndrome	0.004	0.995	0.000
G44.1 Vascular headache, not elsewhere classified	0.004	0.995	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.996	0.004
N04.9 Unspecified	0.000	0.996	0.004
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.996	0.000
G82.5 Tetraplegia, unspecified	0.000	0.996	0.004
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.004
N60.1 Diffuse cystic mastopathy	0.000	0.996	0.004
G44.3 Chronic posttraumatic headache	0.004	0.996	0.000
G82.4 Spastic tetraplegia	0.000	0.996	0.004
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.004	0.996	0.000
K02.9 Dental caries, unspecified	0.000	0.996	0.004
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.996	0.004
E23.6 Other disorders of pituitary gland	0.000	0.996	0.004
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.996	0.004
G82 Paraplegia and tetraplegia	0.000	0.996	0.004
M41.99 Scoliosis, unspecified (Site unspecified)	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.996	0.004
M96.5 Postradiation scoliosis	0.000	0.996	0.004
M96.4 Postsurgical lordosis	0.000	0.996	0.004
M96.3 Postlaminectomy kyphosis	0.000	0.996	0.004
M96.2 Postradiation kyphosis	0.000	0.996	0.004
G82.1 Spastic paraplegia	0.000	0.996	0.004
K02.8 Other dental caries	0.000	0.996	0.004
M41.94 Scoliosis, unspecified (Thoracic region)	0.004	0.996	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.996	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.004	0.996	0.000
E61.1 Iron deficiency	0.002	0.996	0.002
G71.1 Myotonic disorders	0.000	0.996	0.004
M41.96 Scoliosis, unspecified (Lumbar region)	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.001	0.997	0.003
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
K02 Dental caries	0.000	0.997	0.003
E28.3 Primary ovarian failure	0.001	0.997	0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
E11.9 Without complications	0.000	0.997	0.003
G82.3 Flaccid tetraplegia	0.000	0.997	0.003
G82.0 Flaccid paraplegia	0.000	0.997	0.003
K56.4 Other impaction of intestine	0.003	0.997	0.000
M79.10 Myalgia (Multiple sites)	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
C18.7 Sigmoid colon	0.000	0.997	0.003
G71 Primary disorders of muscles	0.000	0.997	0.003
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.997	0.003
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.997	0.003
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.997	0.003
K02.1 Caries of dentin	0.000	0.997	0.003
C71.2 Temporal lobe	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
E21.2 Other hyperparathyroidism	0.000	0.997	0.003
K22.0 Achalasia of cardia	0.003	0.997	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations