TreeWAS – Variant ID: rs62506864

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D70 Agranulocytosis	0.032	0.968	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.032	0.968	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.030	0.970	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.028	0.972	0.000
D75 Other diseases of blood and blood-forming organs	0.028	0.972	0.000
D68 Other coagulation defects	0.027	0.973	0.000
D60-D64 Aplastic and other anaemias	0.027	0.973	0.000
D68.9 Coagulation defect, unspecified	0.025	0.975	0.000
D50-D53 Nutritional anaemias	0.025	0.975	0.000
D64 Other anaemias	0.025	0.975	0.000
D73 Diseases of spleen	0.024	0.975	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.024	0.976	0.000
D64.9 Anaemia, unspecified	0.024	0.976	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.023	0.977	0.000
D74 Methaemoglobinaemia	0.023	0.977	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.023	0.977	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.023	0.977	0.000
D66 Hereditary factor VIII deficiency	0.023	0.977	0.000
D75.1 Secondary polycythaemia	0.022	0.977	0.000
D72 Other disorders of white blood cells	0.022	0.978	0.000
D62 Acute posthaemorrhagic anaemia	0.022	0.978	0.000
D55-D59 Haemolytic anaemias	0.021	0.979	0.000
D68.6 Other Thrombophilia	0.021	0.979	0.000
D68.0 Von Willebrand's disease	0.021	0.979	0.000
D50 Iron deficiency anaemia	0.021	0.979	0.000
D68.2 Hereditary deficiency of other clotting factors	0.021	0.979	0.000
D75.2 Essential thrombocytosis	0.020	0.979	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.020	0.980	0.000
D67 Hereditary factor IX deficiency	0.020	0.980	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.020	0.980	0.000
D73.5 Infarction of spleen	0.020	0.980	0.000
D75.0 Familial erythrocytosis	0.020	0.980	0.000
D80-D89 Certain disorders involving the immune mechanism	0.020	0.980	0.000
D68.5 Primary Thrombophilia	0.019	0.980	0.000
D68.4 Acquired coagulation factor deficiency	0.019	0.980	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.019	0.980	0.000
D68.1 Hereditary factor XI deficiency	0.019	0.980	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.019	0.981	0.000
D52 Folate deficiency anaemia	0.019	0.981	0.000
D68.8 Other specified coagulation defects	0.019	0.981	0.000
D51 Vitamin B12 deficiency anaemia	0.019	0.981	0.000
D61 Other aplastic anaemias	0.018	0.982	0.000
D53 Other nutritional anaemias	0.018	0.982	0.000
D69 Purpura and other haemorrhagic conditions	0.018	0.982	0.000
D64.8 Other specified anaemias	0.018	0.982	0.000
D64.4 Congenital dyserythropoietic anaemia	0.018	0.982	0.000
D64.3 Other sideroblastic anaemias	0.018	0.982	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.018	0.982	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.018	0.982	0.000
D64.0 Hereditary sideroblastic anaemia	0.018	0.982	0.000
D73.9 Disease of spleen, unspecified	0.018	0.982	0.000
D73.8 Other diseases of spleen	0.018	0.982	0.000
D73.4 Cyst of spleen	0.018	0.982	0.000
D73.3 Abscess of spleen	0.018	0.982	0.000
D73.2 Chronic congestive splenomegaly	0.018	0.982	0.000
D73.1 Hypersplenism	0.018	0.982	0.000
D50.9 Iron deficiency anaemia, unspecified	0.018	0.982	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.018	0.982	0.000
D50.8 Other iron deficiency anaemias	0.017	0.983	0.000
D74.9 Methaemoglobinaemia, unspecified	0.017	0.983	0.000
D74.8 Other methaemoglobinaemias	0.017	0.983	0.000
D74.0 Congenital methaemoglobinaemia	0.017	0.983	0.000
D76.3 Other histiocytosis syndromes	0.017	0.983	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.017	0.983	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.017	0.983	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.017	0.983	0.000
D73.0 Hyposplenism	0.016	0.983	0.000
D72.9 Disorder of white blood cells, unspecified	0.016	0.984	0.000
D72.1 Eosinophilia	0.016	0.984	0.000
D72.0 Genetic anomalies of leukocytes	0.016	0.984	0.000
D59 Acquired haemolytic anaemia	0.015	0.984	0.000
D58 Other hereditary haemolytic anaemias	0.015	0.984	0.000
D57 Sickle-cell disorders	0.015	0.984	0.000
D56 Thalassaemia	0.015	0.984	0.000
D55 Anaemia due to enzyme disorders	0.015	0.984	0.000
D50.1 Sideropenic dysphagia	0.015	0.985	0.000
D72.8 Other specified disorders of white blood cells	0.015	0.985	0.000
D52.9 Folate deficiency anaemia, unspecified	0.015	0.985	0.000
D84 Other immunodeficiencies	0.015	0.985	0.000
D83 Common variable immunodeficiency	0.015	0.985	0.000
D82 Immunodeficiency associated with other major defects	0.015	0.985	0.000
D81 Combined immunodeficiencies	0.015	0.985	0.000
D80 Immunodeficiency with predominantly antibody defects	0.015	0.985	0.000
D86 Sarcoidosis	0.015	0.985	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.014	0.986	0.000
D60.8 Other acquired pure red cell aplasias	0.014	0.986	0.000
D60.1 Transient acquired pure red cell aplasia	0.014	0.986	0.000
D60.0 Chronic acquired pure red cell aplasia	0.014	0.986	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.014	0.986	0.000
D52.8 Other folate deficiency anaemias	0.014	0.986	0.000
D52.1 Drug-induced folate deficiency anaemia	0.014	0.986	0.000
D52.0 Dietary folate deficiency anaemia	0.014	0.986	0.000
D69.6 Thrombocytopenia, unspecified	0.014	0.986	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.014	0.986	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.013	0.986	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.013	0.986	0.000
D51.2 Transcobalamin II deficiency	0.013	0.986	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.013	0.986	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.013	0.986	0.000
D61.8 Other specified aplastic anaemias	0.013	0.987	0.000
D61.3 Idiopathic aplastic anaemia	0.013	0.987	0.000
D61.2 Aplastic anaemia due to other external agents	0.013	0.987	0.000
D61.1 Drug-induced aplastic anaemia	0.013	0.987	0.000
D61.0 Constitutional aplastic anaemia	0.013	0.987	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.013	0.987	0.000
D53.9 Nutritional anaemia, unspecified	0.013	0.987	0.000
D53.8 Other specified nutritional anaemias	0.013	0.987	0.000
D53.2 Scorbutic anaemia	0.013	0.987	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.013	0.987	0.000
D53.0 Protein deficiency anaemia	0.013	0.987	0.000
D69.9 Haemorrhagic condition, unspecified	0.013	0.987	0.000
D69.8 Other specified haemorrhagic conditions	0.013	0.987	0.000
D69.5 Secondary thrombocytopenia	0.013	0.987	0.000
D69.4 Other primary thrombocytopenia	0.013	0.987	0.000
D69.2 Other nonthrombocytopenic purpura	0.013	0.987	0.000
D69.1 Qualitative platelet defects	0.013	0.987	0.000
D69.0 Allergic purpura	0.013	0.987	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.013	0.987	0.000
D63.0 Anaemia in neoplastic disease	0.012	0.987	0.000
D61.9 Aplastic anaemia, unspecified	0.012	0.988	0.000
D86.1 Sarcoidosis of lymph nodes	0.012	0.988	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.011	0.988	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.011	0.988	0.000
D55.8 Other anaemias due to enzyme disorders	0.011	0.988	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.011	0.988	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.011	0.988	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.011	0.988	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.011	0.988	0.000
D56.9 Thalassaemia, unspecified	0.011	0.988	0.000
D56.8 Other thalassaemias	0.011	0.988	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.011	0.988	0.000
D56.3 Thalassaemia trait	0.011	0.988	0.000
D56.2 Delta-beta thalassaemia	0.011	0.988	0.000
D56.1 Beta thalassaemia	0.011	0.988	0.000
D56.0 Alpha thalassaemia	0.011	0.988	0.000
D57.8 Other sickle-cell disorders	0.011	0.988	0.000
D57.3 Sickle-cell trait	0.011	0.988	0.000
D57.2 Double heterozygous sickling disorders	0.011	0.988	0.000
D57.1 Sickle-cell anaemia without crisis	0.011	0.988	0.000
D57.0 Sickle-cell anaemia with crisis	0.011	0.988	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.011	0.988	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.011	0.988	0.000
D58.2 Other haemoglobinopathies	0.011	0.988	0.000
D58.1 Hereditary elliptocytosis	0.011	0.988	0.000
D58.0 Hereditary spherocytosis	0.011	0.988	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.011	0.988	0.000
D59.8 Other acquired haemolytic anaemias	0.011	0.988	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.011	0.988	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.011	0.988	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.011	0.988	0.000
D59.3 Haemolytic-uraemic syndrome	0.011	0.988	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.011	0.988	0.000
D59.1 Other autoimmune haemolytic anaemias	0.011	0.988	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.011	0.988	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.011	0.989	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.011	0.989	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.011	0.989	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.011	0.989	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.011	0.989	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.011	0.989	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.011	0.989	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.011	0.989	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.011	0.989	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.011	0.989	0.000
D81.9 Combined immunodeficiency, unspecified	0.011	0.989	0.000
D81.8 Other combined immunodeficiencies	0.011	0.989	0.000
D81.7 Major histocompatibility complex class II deficiency	0.011	0.989	0.000
D81.6 Major histocompatibility complex class I deficiency	0.011	0.989	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.011	0.989	0.000
D81.4 Nezelof's syndrome	0.011	0.989	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.011	0.989	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.011	0.989	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.011	0.989	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.011	0.989	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.011	0.989	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.011	0.989	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.011	0.989	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.011	0.989	0.000
D82.2 Immunodeficiency with short-limbed stature	0.011	0.989	0.000
D82.1 Di George's syndrome	0.011	0.989	0.000
D82.0 Wiskott-Aldrich syndrome	0.011	0.989	0.000
D83.9 Common variable immunodeficiency, unspecified	0.011	0.989	0.000
D83.8 Other common variable immunodeficiencies	0.011	0.989	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.011	0.989	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.011	0.989	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.011	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.011	0.989	0.000
D84.8 Other specified immunodeficiencies	0.011	0.989	0.000
D84.1 Defects in the complement system	0.011	0.989	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.011	0.989	0.000
D86.8 Sarcoidosis of other and combined sites	0.011	0.989	0.000
D86.3 Sarcoidosis of skin	0.011	0.989	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.011	0.989	0.000
D86.9 Sarcoidosis, unspecified	0.010	0.989	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.010	0.990	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.010	0.990	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.010	0.990	0.000
D89.3 Immune reconstitution syndrome	0.010	0.990	0.000
D89.1 Cryoglobulinaemia	0.010	0.990	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.010	0.990	0.000
D86.0 Sarcoidosis of lung	0.009	0.990	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.008	0.991	0.000
E87.6 Hypokalaemia	0.007	0.993	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.007	0.993	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.007	0.993	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.007	0.993	0.000
I25.2 Old myocardial infarction	0.000	0.993	0.007
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.007	0.993	0.000
E87.7 Fluid overload	0.007	0.993	0.000
E87.5 Hyperkalaemia	0.007	0.993	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.007	0.993	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.006	0.994	0.000
S90-S99 Injuries to the ankle and foot	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.006	0.994	0.000
S10-S19 Injuries to the neck	0.006	0.994	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.006	0.994	0.000
S80-S89 Injuries to the knee and lower leg	0.006	0.994	0.000
S40-S49 Injuries to the shoulder and upper arm	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
H53.2 Diplopia	0.000	0.994	0.006
E87.2 Acidosis	0.006	0.994	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.006	0.994	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.006	0.994	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.006	0.994	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.006	0.994	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.006	0.994	0.000
M23.3 Other meniscus derangements	0.006	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.994	0.000
T36 Poisoning by systemic antibiotics	0.005	0.994	0.000
T39.0 Salicylates	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.994	0.000
T86 Failure and rejection of transplanted organs and tissues	0.005	0.994	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.005	0.995	0.000
S92 Fracture of foot, except ankle	0.005	0.995	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.005	0.995	0.000
E87.4 Mixed disorder of acid-base balance	0.005	0.995	0.000
E87.3 Alkalosis	0.005	0.995	0.000
T33-T35 Frostbite	0.005	0.995	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.005	0.995	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.005	0.995	0.000
T00-T07 Injuries involving multiple body regions	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
S10 Superficial injury of neck	0.005	0.995	0.000
S42 Fracture of shoulder and upper arm	0.005	0.995	0.000
S81 Open wound of lower leg	0.005	0.995	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.005	0.995	0.000
S00-S09 Injuries to the head	0.005	0.995	0.000
T66-T78 Other and unspecified effects of external causes	0.005	0.995	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.005	0.995	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.005	0.995	0.000
S20-S29 Injuries to the thorax	0.005	0.995	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.005	0.995	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.005	0.995	0.000
S90 Superficial injury of ankle and foot	0.005	0.995	0.000
T59 Toxic effect of other gases, fumes and vapours	0.005	0.995	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.1 Calcium-channel blockers	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
H53 Visual disturbances	0.000	0.995	0.005
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.005	0.995	0.000
S60-S69 Injuries to the wrist and hand	0.005	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
T44.0 Anticholinesterase agents	0.005	0.995	0.000
T79-T79 Certain early complications of trauma	0.005	0.995	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.005	0.995	0.000
T87 Complications peculiar to reattachment and amputation	0.005	0.995	0.000
H53.1 Subjective visual disturbances	0.000	0.995	0.005
S01.0 Open wound of scalp	0.005	0.995	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.005	0.995	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.005	0.995	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.005	0.995	0.000
T82.3 Mechanical complication of other vascular grafts	0.005	0.995	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.005	0.995	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.005	0.995	0.000
T85.2 Mechanical complication of intraocular lens	0.005	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
S41 Open wound of shoulder and upper arm	0.005	0.995	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.005	0.995	0.000
S91 Open wound of ankle and foot	0.005	0.995	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.005	0.995	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
S89 Other and unspecified injuries of lower leg	0.005	0.995	0.000
S99 Other and unspecified injuries of ankle and foot	0.005	0.995	0.000
S98 Traumatic amputation of ankle and foot	0.005	0.995	0.000
S97 Crushing injury of ankle and foot	0.005	0.995	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.005	0.995	0.000
S95 Injury of blood vessels at ankle and foot level	0.005	0.995	0.000
S94 Injury of nerves at ankle and foot level	0.005	0.995	0.000
S42.4 Fracture of lower end of humerus	0.005	0.995	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.005	0.995	0.000
T59.8 Other specified gases, fumes and vapours	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T50.5 Appetite depressants	0.005	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.005	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.995	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.005	0.995	0.000
S82 Fracture of lower leg, including ankle	0.005	0.995	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.995	0.000
E87.0 Hyperosmolality and hypernatraemia	0.005	0.995	0.000
S19 Other and unspecified injuries of neck	0.005	0.995	0.000
S17 Crushing injury of neck	0.005	0.995	0.000
S15 Injury of blood vessels at neck level	0.005	0.995	0.000
S14 Injury of nerves and spinal cord at neck level	0.005	0.995	0.000
S12 Fracture of neck	0.005	0.995	0.000
S11 Open wound of neck	0.005	0.995	0.000
S18 Traumatic amputation at neck level	0.005	0.995	0.000
S16 Injury of muscle and tendon at neck level	0.005	0.995	0.000
S50-S59 Injuries to the elbow and forearm	0.005	0.995	0.000
S01 Open wound of head	0.005	0.995	0.000
S10.9 Superficial injury of neck, part unspecified	0.005	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
S67 Crushing injury of wrist and hand	0.005	0.995	0.000
S88 Traumatic amputation of lower leg	0.005	0.995	0.000
S87 Crushing injury of lower leg	0.005	0.995	0.000
S86 Injury of muscle and tendon at lower leg level	0.005	0.995	0.000
S85 Injury of blood vessels at lower leg level	0.005	0.995	0.000
S84 Injury of nerves at lower leg level	0.005	0.995	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.005	0.995	0.000
S48 Traumatic amputation of shoulder and upper arm	0.004	0.995	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.004	0.995	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.004	0.995	0.000
S44 Injury of nerves at shoulder and upper arm level	0.004	0.995	0.000
S47 Crushing injury of shoulder and upper arm	0.004	0.995	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.005	0.995	0.000
T82.1 Mechanical complication of cardiac electronic device	0.004	0.995	0.000
S40 Superficial injury of shoulder and upper arm	0.004	0.995	0.000
T68 Hypothermia	0.004	0.995	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.004	0.995	0.000
S42.40 Fracture of lower end of humerus (closed)	0.004	0.995	0.000
S61.1 Open wound of finger(s) with damage to nail	0.005	0.995	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.004	0.995	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.004	0.995	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.004	0.995	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.995	0.000
S92.3 Fracture of metatarsal bone	0.004	0.995	0.000
H53.9 Visual disturbance, unspecified	0.000	0.995	0.004
S20 Superficial injury of thorax	0.004	0.995	0.000
S92.5 Fracture of other toe	0.004	0.995	0.000
T40.4 Other synthetic narcotics	0.004	0.996	0.000
S42.2 Fracture of upper end of humerus	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.004	0.996	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.004	0.996	0.000
S37 Injury of urinary and pelvic organs	0.004	0.996	0.000
S36 Injury of intra-abdominal organs	0.004	0.996	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.004	0.996	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.004	0.996	0.000
S31 Open wound of abdomen, lower back and pelvis	0.004	0.996	0.000
S81.9 Open wound of lower leg, part unspecified	0.004	0.996	0.000
S81.0 Open wound of knee	0.004	0.996	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T80.6 Other serum reactions	0.004	0.996	0.000
T80.5 Anaphylactic shock due to serum	0.004	0.996	0.000
T80.4 Rh incompatibility reaction	0.004	0.996	0.000
T80.3 ABO incompatibility reaction	0.004	0.996	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T65 Toxic effect of other and unspecified substances	0.004	0.996	0.000
T63 Toxic effect of contact with venomous animals	0.004	0.996	0.000
T62 Toxic effect of other noxious substances eaten as food	0.004	0.996	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.004	0.996	0.000
T60 Toxic effect of pesticides	0.004	0.996	0.000
T57 Toxic effect of other inorganic substances	0.004	0.996	0.000
T56 Toxic effect of metals	0.004	0.996	0.000
T54 Toxic effect of corrosive substances	0.004	0.996	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.004	0.996	0.000
T52 Toxic effect of organic solvents	0.004	0.996	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.004	0.996	0.000
T58 Toxic effect of carbon monoxide	0.004	0.996	0.000
T55 Toxic effect of soaps and detergents	0.004	0.996	0.000
H53.8 Other visual disturbances	0.000	0.996	0.004
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
S61 Open wound of wrist and hand	0.004	0.996	0.000
M23.37 Other meniscus derangements-Capsular lig	0.004	0.996	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.004	0.996	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.004	0.996	0.000
S13.4 Sprain and strain of cervical spine	0.004	0.996	0.000
S06 Intracranial injury	0.004	0.996	0.000
T81 Complications of procedures, not elsewhere classified	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.5 Anticoagulants	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T36.3 Macrolides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.004	0.996	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.004	0.996	0.000
S82.5 Fracture of medial malleolus	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations