TreeWAS – Variant ID: rs639012

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I51.7 Cardiomegaly	0.000	0.965	0.035
I51 Complications and ill-defined descriptions of heart disease	0.000	0.975	0.025
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.975	0.025
I51.8 Other ill-defined heart diseases	0.000	0.977	0.023
J84 Other interstitial pulmonary diseases	0.000	0.978	0.022
I51.6 Cardiovascular disease, unspecified	0.000	0.978	0.022
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.978	0.022
I51.5 Myocardial degeneration	0.000	0.979	0.021
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.980	0.020
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.980	0.020
I51.0 Cardiac septal defect, acquired	0.000	0.980	0.020
K35.8 Acute appendicitis, other and unspecified	0.019	0.981	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.981	0.018
J84.8 Other specified interstitial pulmonary diseases	0.000	0.982	0.018
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.982	0.018
K35.1 Acute appendicitis with peritoneal abscess	0.017	0.983	0.000
K35 Acute appendicitis	0.017	0.983	0.000
I51.4 Myocarditis, unspecified	0.000	0.984	0.016
D45 Polycythaemia vera	0.000	0.984	0.016
J84.0 Alveolar and parietoalveolar conditions	0.000	0.984	0.016
K35.3 Acute appendicitis with localized peritonitis	0.015	0.985	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.986	0.014
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.986	0.014
K35.2 Acute appendicitis with generalized peritonitis	0.014	0.986	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.987	0.013
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.987	0.013
D47.2 Monoclonal gammopathy	0.000	0.987	0.013
K35.0 Acute appendicitis with generalised peritonitis	0.013	0.987	0.000
D44.1 Adrenal gland	0.000	0.988	0.012
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.988	0.012
D44.6 Carotid body	0.000	0.988	0.012
D44.8 Pluriglandular involvement	0.000	0.988	0.011
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.989	0.011
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.989	0.011
D44.7 Aortic body and other paraganglia	0.000	0.989	0.011
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.989	0.010
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.989	0.010
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.990	0.010
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.990	0.010
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.990	0.010
D44.4 Craniopharyngeal duct	0.000	0.990	0.010
D40.1 Testis	0.000	0.990	0.010
D44.9 Endocrine gland, unspecified	0.000	0.990	0.010
D44.5 Pineal gland	0.000	0.990	0.010
D44.2 Parathyroid gland	0.000	0.990	0.010
Z36 Antenatal screening	0.000	0.990	0.010
D44.0 Thyroid gland	0.000	0.991	0.009
S51.0 Open wound of elbow	0.000	0.991	0.009
D46 Myelodysplastic syndromes	0.000	0.991	0.009
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.991	0.009
D38.5 Other respiratory organs	0.000	0.991	0.009
D40.7 Other male genital organs	0.000	0.991	0.009
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.991	0.009
D42.9 Meninges, unspecified	0.000	0.991	0.009
D40.0 Prostate	0.000	0.991	0.008
D40.9 Male genital organ, unspecified	0.000	0.991	0.008
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.992	0.008
D38.0 Larynx	0.000	0.992	0.008
D47.4 Osteomyelofibrosis	0.000	0.992	0.008
D42.1 Spinal meninges	0.000	0.992	0.008
D42.0 Cerebral meninges	0.000	0.992	0.008
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.992	0.008
D38.6 Respiratory organ, unspecified	0.000	0.992	0.007
D38.4 Thymus	0.000	0.992	0.007
D38.2 Pleura	0.000	0.992	0.007
D44.3 Pituitary gland	0.000	0.992	0.007
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.992	0.008
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.992	0.007
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.993	0.007
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.993	0.007
Z36.5 Antenatal screening for isoimmunisation	0.000	0.993	0.007
J13 Pneumonia due to Streptococcus pneumoniae	0.007	0.993	0.000
D38.1 Trachea, bronchus and lung	0.000	0.993	0.007
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.993	0.007
D38.3 Mediastinum	0.000	0.993	0.007
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.993	0.007
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.993	0.007
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.993	0.007
D48.0 Bone and articular cartilage	0.000	0.993	0.007
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.993	0.007
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.993	0.007
Z36.8 Other antenatal screening	0.000	0.993	0.007
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.993	0.006
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.993	0.007
D46.4 Refractory anaemia, unspecified	0.000	0.993	0.006
D46.7 Other myelodysplastic syndromes	0.000	0.994	0.006
S51.8 Open wound of other parts of forearm	0.000	0.994	0.006
D43.1 Brain, infratentorial	0.000	0.994	0.006
D46.2 Refractory anaemia with excess of blasts	0.000	0.994	0.006
D43.4 Spinal cord	0.000	0.994	0.006
D43.9 Central nervous system, unspecified	0.000	0.994	0.006
D43.7 Other parts of central nervous system	0.000	0.994	0.006
D43.3 Cranial nerves	0.000	0.994	0.006
D46.1 Refractory anaemia with sideroblasts	0.000	0.994	0.006
D48.4 Peritoneum	0.000	0.994	0.006
D43.0 Brain, supratentorial	0.000	0.994	0.006
S51 Open wound of forearm	0.000	0.994	0.006
D23.5 Skin of trunk	0.006	0.994	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.005	0.995	0.000
D48.7 Other specified sites	0.000	0.995	0.005
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.995	0.005
H57 Other disorders of eye and adnexa	0.000	0.995	0.005
D41.1 Renal pelvis	0.000	0.995	0.005
D48.3 Retroperitoneum	0.000	0.995	0.005
H57.0 Anomalies of pupillary function	0.000	0.995	0.005
Z29.2 Other prophylactic chemotherapy	0.000	0.995	0.005
D41.2 Ureter	0.000	0.995	0.005
I51.9 Heart disease, unspecified	0.000	0.995	0.005
M87.9 Osteonecrosis, unspecified	0.000	0.995	0.005
D41.9 Urinary organ, unspecified	0.000	0.995	0.005
D41.7 Other urinary organs	0.000	0.995	0.005
D41.3 Urethra	0.000	0.995	0.005
D41.0 Kidney	0.000	0.995	0.005
D39.9 Female genital organ, unspecified	0.000	0.995	0.005
D39.2 Placenta	0.000	0.995	0.005
D39.0 Uterus	0.000	0.995	0.005
R60.9 Oedema, unspecified	0.005	0.995	0.000
H57.1 Ocular pain	0.000	0.995	0.005
H57.8 Other specified disorders of eye and adnexa	0.000	0.996	0.004
D39.7 Other female genital organs	0.000	0.996	0.004
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.996	0.004
D48.6 Breast	0.000	0.996	0.004
I34.1 Mitral (valve) prolapse	0.000	0.996	0.004
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.996	0.004
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.996	0.004
A63.0 Anogenital (venereal) warts	0.000	0.996	0.004
R25.1 Tremor, unspecified	0.000	0.996	0.004
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.996	0.004
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.996	0.004
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.996	0.004
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.996	0.004
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.996	0.004
N89.5 Stricture and atresia of vagina	0.000	0.996	0.004
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.996	0.004
J12.9 Viral pneumonia, unspecified	0.004	0.996	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.996	0.004
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.996	0.004
J12 Viral pneumonia, not elsewhere classified	0.004	0.996	0.000
D43.2 Brain, unspecified	0.000	0.996	0.003
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.004	0.996	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.003	0.996	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.997	0.003
T88.4 Failed or difficult intubation	0.000	0.997	0.003
J17 Pneumonia in diseases classified elsewhere	0.003	0.997	0.000
J12.2 Parainfluenza virus pneumonia	0.003	0.997	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.997	0.003
E87.1 Hypo-osmolality and hyponatraemia	0.003	0.997	0.000
D39.1 Ovary	0.000	0.997	0.003
S51.7 Multiple open wounds of forearm	0.000	0.997	0.003
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.997	0.003
D48.1 Connective and other soft tissue	0.000	0.997	0.003
J09-J18 Influenza and pneumonia	0.003	0.997	0.000
J12.1 Respiratory syncytial virus pneumonia	0.003	0.997	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.003	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
Z51.8 Other specified medical care	0.000	0.997	0.003
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.997	0.003
J12.8 Other viral pneumonia	0.003	0.997	0.000
J12.3 Human metapneumovirus pneumonia	0.003	0.997	0.000
J12.0 Adenoviral pneumonia	0.003	0.997	0.000
G59.0 Diabetic mononeuropathy	0.003	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.997	0.003
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.997	0.003
S67.0 Crushing injury of thumb and other finger(s)	0.003	0.997	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.997	0.003
J17.8 Pneumonia in other diseases classified elsewhere	0.003	0.997	0.000
J17.2 Pneumonia in mycoses	0.003	0.997	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.997	0.003
J17.3 Pneumonia in parasitic diseases	0.002	0.997	0.000
Q63.0 Accessory kidney	0.000	0.997	0.003
J11 Influenza, virus not identified	0.002	0.997	0.000
H26.1 Traumatic cataract	0.000	0.997	0.002
X62.9 Unspecified place	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
J09 Influenza due to certain identified influenza virus	0.002	0.998	0.000
N89.0 Mild vaginal dysplasia	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.002	0.998	0.000
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
N76.0 Acute vaginitis	0.000	0.998	0.002
Z81.8 Family history of other mental and behavioural disorders	0.000	0.998	0.002
D48.5 Skin	0.000	0.998	0.002
N89.4 Leukoplakia of vagina	0.000	0.998	0.002
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
D35.1 Parathyroid gland	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.998	0.002
M87 Osteonecrosis	0.000	0.998	0.002
N89.1 Moderate vaginal dysplasia	0.000	0.998	0.002
J11.8 Influenza with other manifestations, virus not identified	0.002	0.998	0.000
N89.7 Haematocolpos	0.000	0.998	0.002
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.998	0.002
Z29 Need for other prophylactic measures	0.000	0.998	0.002
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
Z94.7 Corneal transplant status	0.000	0.998	0.002
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
N89.3 Dysplasia of vagina, unspecified	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.998	0.002
J81 Pulmonary oedema	0.000	0.998	0.002
J15.5 Pneumonia due to Escherichia coli	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.998	0.000
Y84.0 Cardiac catheterisation	0.000	0.998	0.002
J14 Pneumonia due to Haemophilus influenzae	0.002	0.998	0.000
J16.0 Chlamydial pneumonia	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.998	0.002
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.998	0.002
J11.0 Influenza with pneumonia, virus not identified	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.998	0.002
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.998	0.002
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.998	0.002
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.998	0.002
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.998	0.002
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.998	0.002
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
J16.8 Pneumonia due to other specified infectious organisms	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.000	0.998	0.002
Z29.9 Prophylactic measure, unspecified	0.000	0.998	0.002
M87.3 Other secondary osteonecrosis	0.000	0.998	0.002
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
Z43.3 Attention to colostomy	0.000	0.998	0.002
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.002
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.002
J15.4 Pneumonia due to other streptococci	0.002	0.998	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.000	0.998	0.002
M88 Paget's disease of bone [osteitis deformans]	0.000	0.998	0.002
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.000	0.998	0.001
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.000	0.998	0.001
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.000	0.998	0.001
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.000	0.998	0.001
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.000	0.998	0.001
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.000	0.998	0.001
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.000	0.998	0.001
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.000	0.998	0.001
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.000	0.998	0.001
M87.8 Other osteonecrosis	0.000	0.998	0.001
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.998	0.002
I87.8 Other specified disorders of veins	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
J10 Influenza due to identified influenza virus	0.001	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.000	0.998	0.001
M87.18 Osteonecrosis due to drugs (Other)	0.000	0.998	0.001
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.000	0.998	0.001
M87.16 Osteonecrosis due to drugs (Lower leg)	0.000	0.998	0.001
M87.14 Osteonecrosis due to drugs (Hand)	0.000	0.998	0.001
M87.13 Osteonecrosis due to drugs (Forearm)	0.000	0.998	0.001
M87.12 Osteonecrosis due to drugs (Upper arm)	0.000	0.998	0.001
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.000	0.998	0.001
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.000	0.998	0.001
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
Z49.2 Other dialysis	0.000	0.998	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.001	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.998	0.002
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.000	0.998	0.001
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
N89.6 Tight hymenal ring	0.000	0.998	0.001
M89 Other disorders of bone	0.000	0.998	0.002
M87.39 Other secondary osteonecrosis (Site unspecified)	0.000	0.998	0.001
M87.38 Other secondary osteonecrosis (Other)	0.000	0.998	0.001
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.000	0.998	0.001
M87.36 Other secondary osteonecrosis (Lower leg)	0.000	0.998	0.001
M87.34 Other secondary osteonecrosis (Hand)	0.000	0.998	0.001
M87.33 Other secondary osteonecrosis (Forearm)	0.000	0.998	0.001
M87.32 Other secondary osteonecrosis (Upper arm)	0.000	0.998	0.001
M87.31 Other secondary osteonecrosis (Shoulder region)	0.000	0.998	0.001
M87.30 Other secondary osteonecrosis (Multiple sites)	0.000	0.998	0.001
J15.8 Other bacterial pneumonia	0.001	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
Z29.0 Isolation	0.000	0.998	0.002
K36 Other appendicitis	0.000	0.998	0.001
M41.86 Other forms of scoliosis (Lumbar region)	0.000	0.998	0.002
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.998	0.001
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.001
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.001
B35.4 Tinea corporis	0.001	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.001	0.998	0.001
Q63.3 Hyperplastic and giant kidney	0.000	0.998	0.001
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.000	0.998	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.001
M88.0 Paget's disease of skull	0.000	0.998	0.001
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.000	0.998	0.001
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
M89.5 Osteolysis	0.000	0.998	0.001
S31.8 Open wound of other and unspecified parts of abdomen	0.000	0.998	0.001
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.998	0.001
M87.88 Other osteonecrosis (Other)	0.000	0.998	0.001
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.998	0.001
M87.84 Other osteonecrosis (Hand)	0.000	0.998	0.001
M87.83 Other osteonecrosis (Forearm)	0.000	0.998	0.001
M87.82 Other osteonecrosis (Upper arm)	0.000	0.998	0.001
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.998	0.001
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.998	0.001
M87.2 Osteonecrosis due to previous trauma	0.000	0.998	0.001
M89.3 Hypertrophy of bone	0.000	0.998	0.001
B35 Dermatophytosis	0.001	0.998	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.999	0.001
J15.2 Pneumonia due to staphylococcus	0.001	0.999	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.001	0.999	0.000
M87.86 Other osteonecrosis (Lower leg)	0.000	0.999	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
X62.0 Home	0.001	0.999	0.000
X62.7 Farm	0.001	0.999	0.000
X62.6 Industrial and construction area	0.001	0.999	0.000
X62.5 Trade and service area	0.001	0.999	0.000
X62.4 Street and highway	0.001	0.999	0.000
X62.3 Sports and athletics area	0.001	0.999	0.000
X62.2 School, other institution and public administrative area	0.001	0.999	0.000
X62.1 Residential institution	0.001	0.999	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.8 Paget's disease of other bones	0.000	0.999	0.001
M89.6 Osteopathy after poliomyelitis	0.000	0.999	0.001
M89.2 Other disorders of bone development and growth	0.000	0.999	0.001
M89.1 Epiphyseal arrest	0.000	0.999	0.001
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.999	0.001
X68.9 Unspecified place	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.999	0.001
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.999	0.001
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.999	0.001
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.999	0.001
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.999	0.001
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.999	0.001
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.999	0.001
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.999	0.001
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.999	0.001
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.999	0.001
G57.1 Meralgia paraesthetica	0.001	0.999	0.000
M86-M90 Other osteopathies	0.000	0.999	0.001
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.999	0.001
B35.9 Dermatophytosis, unspecified	0.001	0.999	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.999	0.001
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.999	0.001
Z49.0 Preparatory care for dialysis	0.000	0.999	0.001
F40 Phobic anxiety disorders	0.000	0.999	0.001
M88.09 Paget's disease of skull-Site unspec	0.000	0.999	0.001
M88.08 Paget's disease of skull-Other	0.000	0.999	0.001
M88.07 Paget's disease of skull-Ankle/Foot	0.000	0.999	0.001
M88.06 Paget's disease of skull-Lower Leg	0.000	0.999	0.001
M88.05 Paget's disease of skull-Pelvic/Thigh	0.000	0.999	0.001
M88.04 Paget's disease of skull-Hand	0.000	0.999	0.001
M88.03 Paget's disease of skull-Forearm	0.000	0.999	0.001
M88.02 Paget's disease of skull-Upper arm	0.000	0.999	0.001
M88.01 Paget's disease of skull-Shldr region	0.000	0.999	0.001
M88.00 Paget's disease of skull-Mult sites	0.000	0.999	0.001
C90.0 Multiple myeloma	0.000	0.999	0.001
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.999	0.001
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.999	0.001
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.999	0.001
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.999	0.001
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.999	0.001
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.999	0.001
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.999	0.001
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.999	0.001
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.999	0.001
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.999	0.001
M89.34 Hypertrophy of bone (Hand)	0.000	0.999	0.001
M89.33 Hypertrophy of bone (Forearm)	0.000	0.999	0.001
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.999	0.001
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.999	0.001
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.999	0.001
M89.59 Osteolysis (Site unspecified)	0.000	0.999	0.001
M89.58 Osteolysis (Other)	0.000	0.999	0.001
M89.57 Osteolysis (Ankle and foot)	0.000	0.999	0.001
M89.54 Osteolysis (Hand)	0.000	0.999	0.001
M89.53 Osteolysis (Forearm)	0.000	0.999	0.001
M89.52 Osteolysis (Upper arm)	0.000	0.999	0.001
M89.51 Osteolysis (Shoulder region)	0.000	0.999	0.001
M89.50 Osteolysis (Multiple sites)	0.000	0.999	0.001
B35.8 Other dermatophytoses	0.001	0.999	0.000
B35.5 Tinea imbricata	0.001	0.999	0.000
B35.2 Tinea manuum	0.001	0.999	0.000
B35.0 Tinea barbae and tinea capitis	0.001	0.999	0.000
F40.1 Social phobias	0.000	0.999	0.001
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.999	0.001
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.999	0.001
M89.38 Hypertrophy of bone (Other)	0.000	0.999	0.001
M89.56 Osteolysis (Lower leg)	0.000	0.999	0.001
S54.0 Injury of ulnar nerve at forearm level	0.000	0.999	0.001
M06.34 Rheumatoid nodule (Hand)	0.001	0.999	0.000
B35.6 Tinea cruris	0.001	0.999	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.999	0.001
S50.9 Superficial injury of forearm, unspecified	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.999	0.001
M88.89 Paget's disease of other bones (Site unspecified)	0.000	0.999	0.001
M88.88 Paget's disease of other bones (Other)	0.000	0.999	0.001
M88.87 Paget's disease of other bones (Ankle and foot)	0.000	0.999	0.001
M88.86 Paget's disease of other bones (Lower leg)	0.000	0.999	0.001
M88.84 Paget's disease of other bones (Hand)	0.000	0.999	0.001
M88.83 Paget's disease of other bones (Forearm)	0.000	0.999	0.001
M88.82 Paget's disease of other bones (Upper arm)	0.000	0.999	0.001
M88.81 Paget's disease of other bones (Shoulder region)	0.000	0.999	0.001
M88.80 Paget's disease of other bones (Multiple sites)	0.000	0.999	0.001
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.999	0.001
M89.18 Epiphyseal arrest (Other)	0.000	0.999	0.001
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.999	0.001
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.999	0.001
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.999	0.001
M89.14 Epiphyseal arrest (Hand)	0.000	0.999	0.001
M89.13 Epiphyseal arrest (Forearm)	0.000	0.999	0.001
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.999	0.001
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.999	0.001
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.999	0.001
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.999	0.001
M89.28 Other disorders of bone development and growth (Other)	0.000	0.999	0.001
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.999	0.001
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.999	0.001
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.999	0.001
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.999	0.001
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.999	0.001
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.999	0.001
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.999	0.001
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.999	0.001
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.999	0.001
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.999	0.001
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.999	0.001
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.999	0.001
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.999	0.001
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.999	0.001
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.999	0.001
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.999	0.001
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.999	0.001
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.001	0.999	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.999	0.001
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.999	0.001
M20.3 Other deformity of hallux (acquired)	0.001	0.999	0.000
M77.1 Lateral epicondylitis	0.000	0.999	0.001
X62.8 Other specified place	0.001	0.999	0.000
X69.0 Home	0.001	0.999	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.001	0.999	0.000
S02.50 Fracture of tooth (closed)	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
F20.5 Residual schizophrenia	0.000	0.999	0.001
Q39.6 Diverticulum of oesophagus	0.000	0.999	0.001
X69.9 Unspecified place	0.001	0.999	0.000
F20 Schizophrenia	0.000	0.999	0.001
X68 Intentional self-poisoning by and exposure to pesticides	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.000	0.999	0.001
B35.1 Tinea unguium	0.001	0.999	0.000
O81.3 Other and unspecified forceps delivery	0.000	0.999	0.001
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.001	0.999	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.999	0.001
F20.2 Catatonic schizophrenia	0.000	0.999	0.001
J10.0 Influenza with pneumonia, influenza virus identified	0.001	0.999	0.000
C15.3 Upper third of oesophagus	0.000	0.999	0.001
Q39.4 Oesophageal web	0.000	0.999	0.001
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.999	0.001
M25.43 Effusion of joint (Forearm)	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.000	0.999	0.001
X84.0 Home	0.001	0.999	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.999	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.999	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.999	0.001
M77.18 Lateral epicondylitis-Other	0.000	0.999	0.001
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.999	0.001
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.999	0.001
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.999	0.001
M77.14 Lateral epicondylitis-Hand	0.000	0.999	0.001
M77.11 Lateral epicondylitis-Shldr region	0.000	0.999	0.001
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.999	0.001
G59.8 Other mononeuropathies in diseases classified elsewhere	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.000	0.999	0.001
F20.4 Postschizophrenic depression	0.000	0.999	0.001
F20.3 Undifferentiated schizophrenia	0.000	0.999	0.001
F20.1 Hebephrenic schizophrenia	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations