TreeWAS – Variant ID: rs6427782

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N90.5 Atrophy of vulva	0.130	0.870	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.959	0.041
I05 Rheumatic mitral valve diseases	0.033	0.967	0.000
I05.2 Mitral stenosis with insufficiency	0.032	0.968	0.000
I07.1 Tricuspid insufficiency	0.031	0.969	0.000
I05.0 Mitral stenosis	0.031	0.969	0.000
I07 Rheumatic tricuspid valve diseases	0.030	0.970	0.000
I05-I09 Chronic rheumatic heart diseases	0.030	0.970	0.000
I09 Other rheumatic heart diseases	0.028	0.972	0.000
I05.1 Rheumatic mitral insufficiency	0.028	0.972	0.000
I09.9 Rheumatic heart disease, unspecified	0.027	0.973	0.000
I05.8 Other mitral valve diseases	0.025	0.975	0.000
I06 Rheumatic aortic valve diseases	0.024	0.976	0.000
I05.9 Mitral valve disease, unspecified	0.022	0.978	0.000
I07.9 Tricuspid valve disease, unspecified	0.022	0.978	0.000
I07.8 Other tricuspid valve diseases	0.022	0.978	0.000
I07.2 Tricuspid stenosis with insufficiency	0.022	0.978	0.000
I07.0 Tricuspid stenosis	0.022	0.978	0.000
N60.4 Mammary duct ectasia	0.021	0.979	0.000
I09.8 Other specified rheumatic heart diseases	0.020	0.980	0.000
I09.2 Chronic rheumatic pericarditis	0.020	0.980	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.020	0.980	0.000
I09.0 Rheumatic myocarditis	0.020	0.980	0.000
N60.2 Fibroadenosis of breast	0.020	0.980	0.000
N60 Benign mammary dysplasia	0.020	0.980	0.000
N60.3 Fibrosclerosis of breast	0.020	0.980	0.000
I06.1 Rheumatic aortic insufficiency	0.019	0.981	0.000
I06.0 Rheumatic aortic stenosis	0.018	0.982	0.000
I06.8 Other rheumatic aortic valve diseases	0.017	0.983	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.017	0.983	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.017	0.983	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.017	0.983	0.000
D86.9 Sarcoidosis, unspecified	0.016	0.984	0.000
D86 Sarcoidosis	0.014	0.986	0.000
N60.0 Solitary cyst of breast	0.014	0.986	0.000
N60.1 Diffuse cystic mastopathy	0.013	0.987	0.000
D86.8 Sarcoidosis of other and combined sites	0.013	0.987	0.000
N60.9 Benign mammary dysplasia, unspecified	0.012	0.988	0.000
D86.3 Sarcoidosis of skin	0.012	0.988	0.000
N60.8 Other benign mammary dysplasias	0.012	0.988	0.000
D86.0 Sarcoidosis of lung	0.011	0.989	0.000
M50.3 Other cervical disk degeneration	0.011	0.989	0.000
D86.1 Sarcoidosis of lymph nodes	0.011	0.989	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.010	0.990	0.000
I08 Multiple valve diseases	0.010	0.990	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.010	0.990	0.000
Z00.0 General medical examination	0.010	0.990	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.009	0.991	0.000
B37.9 Candidiasis, unspecified	0.000	0.991	0.009
I08.8 Other multiple valve diseases	0.009	0.991	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.009	0.991	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.009	0.991	0.000
J38.0 Paralysis of vocal cords and larynx	0.009	0.991	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.991	0.009
H66.9 Otitis media, unspecified	0.000	0.992	0.008
S52.10 Fracture of upper end of radius (closed)	0.008	0.992	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.008	0.992	0.000
Z00.3 Examination for adolescent development state	0.007	0.992	0.000
Z00.2 Examination for period of rapid growth in childhood	0.007	0.992	0.000
Z00.1 Routine child health examination	0.007	0.992	0.000
Z00.8 Other general examinations	0.007	0.993	0.000
I33.0 Acute and subacute infective endocarditis	0.007	0.993	0.000
J38.4 Oedema of larynx	0.007	0.993	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.993	0.007
H66 Suppurative and unspecified otitis media	0.000	0.993	0.007
S82.20 Fracture of shaft of tibia (closed)	0.000	0.993	0.007
H66.0 Acute suppurative otitis media	0.000	0.993	0.007
D75.9 Disease of blood and blood-forming organs, unspecified	0.007	0.993	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.993	0.007
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.994	0.006
Z90.3 Acquired absence of part of stomach	0.006	0.994	0.000
I08.9 Multiple valve disease, unspecified	0.006	0.994	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.006	0.994	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.994	0.006
I08.0 Disorders of both mitral and aortic valves	0.006	0.994	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.006	0.994	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.995	0.005
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.995	0.005
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.995	0.005
J38.7 Other diseases of larynx	0.005	0.995	0.000
S82.00 Fracture of patella (closed)	0.000	0.995	0.005
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.995	0.005
J38.6 Stenosis of larynx	0.005	0.995	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.995	0.005
S61 Open wound of wrist and hand	0.000	0.995	0.005
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.995	0.005
M13.09 Polyarthritis, unspecified (Site unspecified)	0.005	0.995	0.000
T20.2 Burn of second degree of head and neck	0.000	0.995	0.005
S60-S69 Injuries to the wrist and hand	0.000	0.995	0.005
D75.8 Other specified diseases of blood and blood-forming organs	0.005	0.995	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.005	0.995	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.995	0.005
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.995	0.005
M13.0 Polyarthritis, unspecified	0.005	0.995	0.000
S60 Superficial injury of wrist and hand	0.000	0.995	0.005
S63.0 Dislocation of wrist	0.000	0.995	0.004
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.996	0.004
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
S65 Injury of blood vessels at wrist and hand level	0.000	0.996	0.004
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.996	0.004
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.996	0.004
Y40.8 Other systemic antibiotics	0.000	0.996	0.004
J38.2 Nodules of vocal cords	0.004	0.996	0.000
S63.5 Sprain and strain of wrist	0.000	0.996	0.004
S67 Crushing injury of wrist and hand	0.000	0.996	0.004
S63.1 Dislocation finger	0.000	0.996	0.004
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.996	0.004
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.996	0.004
I64 Stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.996	0.004
S60.2 Contusion of other parts of wrist and hand	0.000	0.996	0.004
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.996	0.004
S63.2 Multiple dislocations of fingers	0.000	0.996	0.004
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.996	0.004
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.004	0.996	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.996	0.004
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.996	0.004
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.996	0.004
S82.0 Fracture of patella	0.000	0.996	0.004
S65.5 Injury of blood vessel(s) of other finger	0.000	0.996	0.004
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.996	0.004
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.996	0.004
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.996	0.004
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.996	0.004
D75.0 Familial erythrocytosis	0.004	0.996	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.004	0.996	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.996	0.004
Z52.4 Kidney donor	0.000	0.996	0.004
S82.01 Fracture of patella (open)	0.000	0.996	0.004
S82.2 Fracture of shaft of tibia	0.000	0.996	0.004
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.004	0.996	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.996	0.004
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.004	0.996	0.000
D69.5 Secondary thrombocytopenia	0.004	0.996	0.000
M13.08 Polyarthritis, unspecified (Other)	0.003	0.996	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.003	0.996	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.003	0.996	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.003	0.996	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.003	0.996	0.000
J38.5 Laryngeal spasm	0.003	0.996	0.000
S60.1 Contusion of finger(s) with damage to nail	0.000	0.996	0.003
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.996	0.003
M13.04 Polyarthritis, unspecified (Hand)	0.003	0.996	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.997	0.003
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.997	0.003
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.997	0.003
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.997	0.003
S65.3 Injury of deep palmar arch	0.000	0.997	0.003
S65.2 Injury of superficial palmar arch	0.000	0.997	0.003
S65.4 Injury of blood vessel(s) of thumb	0.000	0.997	0.003
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.000	0.997	0.003
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.997	0.003
S65.1 Injury of radial artery at wrist and hand level	0.000	0.997	0.003
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.003	0.997	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.997	0.003
Z00.5 Examination of potential donor of organ and tissue	0.003	0.997	0.001
S52.1 Fracture of upper end of radius	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
T68 Hypothermia	0.000	0.997	0.003
D75.2 Essential thrombocytosis	0.003	0.997	0.000
N90.4 Leukoplakia of vulva	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.997	0.003
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.000	0.997	0.003
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.003	0.997	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
D69.0 Allergic purpura	0.003	0.997	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.997	0.003
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.003	0.997	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.003	0.997	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.997	0.003
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
N90.0 Mild vulvar dysplasia	0.003	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.997	0.003
D68 Other coagulation defects	0.003	0.997	0.000
C69.3 Choroid	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
J38.1 Polyp of vocal cord and larynx	0.003	0.997	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.002	0.997	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.997	0.000
K01.1 Impacted teeth	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
S60.0 Contusion of finger(s) without damage to nail	0.000	0.997	0.002
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.997	0.002
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.997	0.002
S68.4 Traumatic amputation of hand at wrist level	0.000	0.997	0.002
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.997	0.002
R20 Disturbances of skin sensation	0.003	0.997	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.997	0.003
N97.9 Female infertility, unspecified	0.000	0.997	0.003
D84 Other immunodeficiencies	0.002	0.997	0.000
K01.0 Embedded teeth	0.000	0.998	0.002
R00.2 Palpitations	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.002	0.998	0.000
R20.0 Anaesthesia of skin	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
T20.7 Corrosion of third degree of head and neck	0.000	0.998	0.002
T20.6 Corrosion of second degree of head and neck	0.000	0.998	0.002
T20.5 Corrosion of first degree of head and neck	0.000	0.998	0.002
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.998	0.002
S64.8 Injury of other nerves at wrist and hand level	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.000	0.998	0.002
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
N90.1 Moderate vulvar dysplasia	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
T20.3 Burn of third degree of head and neck	0.000	0.998	0.002
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
C69.9 Eye, unspecified	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
I33 Acute and subacute endocarditis	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.998	0.002
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
E27.2 Addisonian crisis	0.000	0.998	0.002
T78.9 Adverse effect, unspecified	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.000	0.998	0.002
D84.1 Defects in the complement system	0.002	0.998	0.000
T20.1 Burn of first degree of head and neck	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
G24.5 Blepharospasm	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.002
N90.3 Dysplasia of vulva, unspecified	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.002	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.998	0.002
M46 Other inflammatory spondylopathies	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
K22.5 Diverticulum of oesophagus, acquired	0.000	0.998	0.002
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.998	0.002
K01 Embedded and impacted teeth	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
C71.2 Temporal lobe	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
Y40 Systemic antibiotics	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
T70 Effects of air pressure and water pressure	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
R20.1 Hypoaesthesia of skin	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
O62.3 Precipitate labour	0.000	0.998	0.002
S64.3 Injury of digital nerve of thumb	0.000	0.998	0.002
A04.8 Other specified bacterial intestinal infections	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
T75 Effects of other external causes	0.000	0.998	0.002
T74 Maltreatment syndromes	0.000	0.998	0.002
T73 Effects of other deprivation	0.000	0.998	0.002
T69 Other effects of reduced temperature	0.000	0.998	0.002
T67 Effects of heat and light	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.000	0.998	0.002
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
D82.1 Di George's syndrome	0.001	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.002	0.998	0.000
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
T75.1 Drowning and nonfatal submersion	0.000	0.998	0.002
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.998	0.002
H02.4 Ptosis of eyelid	0.002	0.998	0.000
T71 Asphyxiation	0.000	0.998	0.002
C69.6 Orbit	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
M46.2 Osteomyelitis of vertebra	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.000	0.998	0.001
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
T66 Unspecified effects of radiation	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.998	0.002
N90.6 Hypertrophy of vulva	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.998	0.002
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.002
C69.5 Lachrymal gland and duct	0.000	0.998	0.002
C69.1 Cornea	0.000	0.998	0.002
M46.8 Other specified inflammatory spondylopathies	0.002	0.998	0.000
M46.5 Other infective spondylopathies	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
Y40.4 Tetracyclines	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.001	0.998	0.000
M46.0 Spinal enthesopathy	0.002	0.998	0.000
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.998	0.002
C69.0 Conjunctiva	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.000	0.998	0.002
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.002	0.998	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.002
H81.0 Meniere's disease	0.000	0.998	0.002
K60.1 Chronic anal fissure	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.000	0.998	0.002
S02.21 Fracture of nasal bones (open)	0.002	0.998	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.998	0.001
T70.8 Other effects of air pressure and water pressure	0.000	0.998	0.001
T70.4 Effects of high-pressure fluids	0.000	0.998	0.001
T70.2 Other and unspecified effects of high altitude	0.000	0.998	0.001
T70.1 Sinus barotrauma	0.000	0.998	0.001
T70.0 Otitic barotrauma	0.000	0.998	0.001
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
C69.4 Ciliary body	0.000	0.998	0.001
M46.4 Discitis, unspecified	0.002	0.998	0.000
N97.0 Female infertility associated with anovulation	0.000	0.998	0.002
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.001
T75.8 Other specified effects of external causes	0.000	0.998	0.001
T75.3 Motion sickness	0.000	0.998	0.001
T75.2 Effects of vibration	0.000	0.998	0.001
T75.0 Effects of lightning	0.000	0.998	0.001
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.001	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
D59.8 Other acquired haemolytic anaemias	0.000	0.998	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.998	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.998	0.001
D59.3 Haemolytic-uraemic syndrome	0.000	0.998	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.998	0.001
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.001
T67.8 Other effects of heat and light	0.000	0.998	0.001
T67.7 Heat oedema	0.000	0.998	0.001
T67.6 Heat fatigue, transient	0.000	0.998	0.001
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.001
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.001
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.001
T67.2 Heat cramp	0.000	0.998	0.001
T67.1 Heat syncope	0.000	0.998	0.001
T67.0 Heatstroke and sunstroke	0.000	0.998	0.001
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.001
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.001
T69.1 Chilblains	0.000	0.998	0.001
T69.0 Immersion hand and foot	0.000	0.998	0.001
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.001
T73.8 Other effects of deprivation	0.000	0.998	0.001
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.001
T73.2 Exhaustion due to exposure	0.000	0.998	0.001
T73.1 Effects of thirst	0.000	0.998	0.001
T73.0 Effects of hunger	0.000	0.998	0.001
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.001
T74.8 Other maltreatment syndromes	0.000	0.998	0.001
T74.3 Psychological abuse	0.000	0.998	0.001
T74.2 Sexual abuse	0.000	0.998	0.001
T74.1 Physical abuse	0.000	0.998	0.001
T74.0 Neglect or abandonment	0.000	0.998	0.001
Y40.5 Aminoglycosides	0.000	0.998	0.002
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
Q54 Hypospadias	0.000	0.998	0.002
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.998	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.001	0.998	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.001	0.998	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.001	0.998	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.001	0.998	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.001	0.998	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.001	0.998	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.001	0.998	0.000
M46.42 Discitis, unspecified (Cervical region)	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
N97.8 Female infertility of other origin	0.000	0.998	0.002
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.001
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.001
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.001
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.001
Y40.3 Macrolides	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
N64 Other disorders of breast	0.002	0.998	0.000
N97 Female infertility	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.001
C69.2 Retina	0.000	0.998	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.001
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.001
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
M25.06 Haemarthrosis (Lower leg)	0.000	0.998	0.002
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.001	0.998	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.001	0.998	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.001	0.998	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.001	0.998	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.001	0.998	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.001	0.998	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.001	0.998	0.000
N64.4 Mastodynia	0.002	0.998	0.000
N64.1 Fat necrosis of breast	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.001	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
S82 Fracture of lower leg, including ankle	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.000	0.998	0.002
M43.09 Spondylolysis (Site unspecified)	0.001	0.998	0.000
F52.0 Lack or loss of sexual desire	0.001	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.001	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T51.9 Alcohol, unspecified	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.000	0.998	0.001
Z50.4 Psychotherapy, not elsewhere classified	0.002	0.998	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations