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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6444087
log Bayes Factor = 0.0756437
Chromosome 3   position 185,621,829  (GRCh37) Explore rs6444087 on Ensembl!
Variant rs6444087 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M54.39 Sciatica (Site unspecified)
0.250 0.750 0.000
M54.3 Sciatica
0.156 0.844 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.131 0.869 0.000
M54.36 Sciatica (Lumbar region)
0.123 0.877 0.000
M54.37 Sciatica (Lumbosacral region)
0.112 0.888 0.000
M54.35 Sciatica (Thoracolumbar region)
0.112 0.888 0.000
M54.34 Sciatica-Thoracic
0.112 0.888 0.000
M54.33 Sciatica-Cervicothoracic
0.112 0.888 0.000
M54.32 Sciatica-Cervical
0.112 0.888 0.000
M54.31 Sciatica-Occipit-atl-axl
0.112 0.888 0.000
M54.30 Sciatica (Multiple sites in spine)
0.089 0.910 0.000
M54.2 Cervicalgia
0.051 0.949 0.000
M54.22 Cervicalgia (Cervical region)
0.049 0.951 0.000
E10 Insulin-dependent diabetes mellitus
0.048 0.952 0.000
M54 Dorsalgia
0.048 0.952 0.000
E10.3 With ophthalmic complications
0.046 0.954 0.000
E10.4 With neurological complications
0.045 0.955 0.000
E10.9 Without complications
0.045 0.955 0.000
E10.1 With ketoacidosis
0.045 0.955 0.000
E10.5 With peripheral circulatory complications
0.045 0.955 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.044 0.956 0.000
M54.29 Cervicalgia-Site unspe
0.043 0.957 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.039 0.961 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.038 0.962 0.000
M54.8 Other dorsalgia
0.037 0.963 0.000
M54.27 Cervicalgia-Lumbosacral
0.037 0.963 0.000
M54.26 Cervicalgia-Lumbar
0.037 0.963 0.000
M54.25 Cervicalgia-Thoracolumbar
0.037 0.963 0.000
M54.24 Cervicalgia-Thoracic
0.037 0.963 0.000
M54.20 Cervicalgia-Mult site
0.037 0.963 0.000
E10.6 With other specified complications
0.035 0.965 0.000
E10.7 With multiple complications
0.035 0.965 0.000
M54.0 Panniculitis affecting regions of neck and back
0.034 0.965 0.000
E10.0 With coma
0.030 0.970 0.000
E10.8 With unspecified complications
0.029 0.970 0.000
M54.4 Lumbago with sciatica
0.029 0.971 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.029 0.971 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.028 0.972 0.000
E10.2 With renal complications
0.027 0.973 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.026 0.973 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.026 0.973 0.000
M54.82 Other dorsalgia (Cervical region)
0.026 0.973 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.026 0.973 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.026 0.973 0.000
M54.84 Other dorsalgia (Thoracic region)
0.026 0.974 0.000
M54.89 Other dorsalgia (Site unspecified)
0.026 0.974 0.000
M54.86 Other dorsalgia (Lumbar region)
0.026 0.974 0.000
M54.6 Pain in thoracic spine
0.025 0.975 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.025 0.975 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.025 0.975 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.025 0.975 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.025 0.975 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.025 0.975 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.025 0.975 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.025 0.975 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.025 0.975 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.025 0.975 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.025 0.975 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.022 0.978 0.000
H27.8 Other specified disorders of lens
0.000 0.978 0.022
M54.46 Lumbago with sciatica (Lumbar region)
0.021 0.979 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.021 0.979 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.021 0.979 0.000
M54.44 Lumbago with sciatica-Thoracic
0.021 0.979 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.021 0.979 0.000
M54.42 Lumbago with sciatica-Cervical
0.021 0.979 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.021 0.979 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.021 0.979 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.019 0.981 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.019 0.981 0.000
M54.69 Pain in thoracic spine-Site unspe
0.018 0.982 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.018 0.982 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.018 0.982 0.000
M54.66 Pain in thoracic spine-Lumbar
0.018 0.982 0.000
M54.62 Pain in thoracic spine-Cervical
0.018 0.982 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.018 0.982 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.018 0.982 0.000
H27 Other disorders of lens
0.000 0.982 0.018
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.018 0.982 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.017 0.982 0.000
H27.0 Aphakia
0.000 0.983 0.017
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.016 0.984 0.000
M54.5 Low back pain
0.015 0.985 0.000
H27.1 Dislocation of lens
0.000 0.985 0.015
M54.1 Radiculopathy
0.015 0.985 0.000
H27.9 Disorder of lens, unspecified
0.000 0.987 0.013
N81.2 Incomplete uterovaginal prolapse
0.000 0.987 0.013
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.987 0.013
M54.19 Radiculopathy (Site unspecified)
0.012 0.987 0.000
L40.0 Psoriasis vulgaris
0.000 0.988 0.012
E10-E14 Diabetes mellitus
0.012 0.988 0.000
E87.0 Hyperosmolality and hypernatraemia
0.012 0.988 0.000
L40 Psoriasis
0.000 0.988 0.012
M54.52 Low back pain-Cervical
0.011 0.989 0.000
M54.54 Low back pain-Thoracic
0.011 0.989 0.000
M54.53 Low back pain-Cervicothoracic
0.011 0.989 0.000
M54.51 Low back pain-Occipit-atl-axl
0.011 0.989 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.989 0.011
E13 Other specified diabetes mellitus
0.011 0.989 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.011 0.989 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.011 0.989 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.011 0.989 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.010 0.989 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.010 0.989 0.000
M54.14 Radiculopathy (Thoracic region)
0.010 0.990 0.000
L40.5 Arthropathic psoriasis
0.000 0.990 0.010
E13.9 Without complications
0.010 0.990 0.000
M54.55 Low back pain (Thoracolumbar region)
0.009 0.991 0.000
M54.12 Radiculopathy (Cervical region)
0.009 0.991 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.991 0.009
E12 Malnutrition-related diabetes mellitus
0.009 0.991 0.000
L40.1 Generalised pustular psoriasis
0.000 0.991 0.009
L40.8 Other psoriasis
0.000 0.991 0.009
L40.4 Guttate psoriasis
0.000 0.991 0.009
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.008 0.991 0.000
L40.2 Acrodermatitis continua
0.000 0.991 0.008
E13.3 With ophthalmic complications
0.008 0.992 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.008 0.992 0.000
E13.8 With unspecified complications
0.008 0.992 0.000
E13.7 With multiple complications
0.008 0.992 0.000
E13.6 With other specified complications
0.008 0.992 0.000
E13.5 With peripheral circulatory complications
0.008 0.992 0.000
E13.4 With neurological complications
0.008 0.992 0.000
E13.2 With renal complications
0.008 0.992 0.000
E13.1 With ketoacidosis
0.008 0.992 0.000
E13.0 With coma
0.008 0.992 0.000
L40.9 Psoriasis, unspecified
0.000 0.992 0.008
N81.5 Vaginal enterocele
0.000 0.993 0.007
E14 Unspecified diabetes mellitus
0.007 0.993 0.000
S42.20 Fracture of upper end of humerus (closed)
0.007 0.993 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.993 0.007
E12.9 Without complications
0.006 0.993 0.000
E12.8 With unspecified complications
0.006 0.993 0.000
E12.7 With multiple complications
0.006 0.993 0.000
E12.6 With other specified complications
0.006 0.993 0.000
E12.5 With peripheral circulatory complications
0.006 0.993 0.000
E12.4 With neurological complications
0.006 0.993 0.000
E12.3 With ophthalmic complications
0.006 0.993 0.000
E12.2 With renal complications
0.006 0.993 0.000
E12.1 With ketoacidosis
0.006 0.993 0.000
E12.0 With coma
0.006 0.993 0.000
M54.50 Low back pain (Multiple sites in spine)
0.006 0.993 0.000
M54.9 Dorsalgia, unspecified
0.007 0.993 0.000
E14.3 With ophthalmic complications
0.007 0.993 0.000
I71.0 Dissection of aorta [any part]
0.007 0.993 0.000
M54.57 Low back pain (Lumbosacral region)
0.007 0.993 0.000
I71 Aortic aneurysm and dissection
0.006 0.994 0.000
T40.2 Other opioids
0.000 0.994 0.006
C67.9 Bladder, unspecified
0.006 0.994 0.000
S06 Intracranial injury
0.000 0.994 0.006
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.994 0.006
E14.4 With neurological complications
0.006 0.994 0.000
E14.6 With other specified complications
0.006 0.994 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.994 0.006
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.994 0.006
S06.2 Diffuse brain injury
0.000 0.994 0.006
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.994 0.006
M54.92 Dorsalgia, unspecified (Cervical region)
0.006 0.994 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.994 0.006
E14.5 With peripheral circulatory complications
0.006 0.994 0.000
E14.2 Withrenal complications
0.006 0.994 0.000
S06.5 Traumatic subdural haemorrhage
0.000 0.994 0.006
I63.8 Other cerebral infarction
0.000 0.994 0.006
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.994 0.006
E14.7 With multiple complications
0.005 0.994 0.000
T50.4 Drugs affecting uric acid metabolism
0.000 0.994 0.006
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.995 0.005
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.995 0.005
E14.1 With ketoacidosis
0.005 0.995 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.995 0.005
T39.1 4-Aminophenol derivatives
0.000 0.995 0.005
M54.16 Radiculopathy (Lumbar region)
0.005 0.995 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.005 0.995 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.995 0.005
L29.9 Pruritus, unspecified
0.000 0.995 0.005
M54.96 Dorsalgia, unspecified (Lumbar region)
0.005 0.995 0.000
E14.8 With unspecified complications
0.005 0.995 0.000
T36 Poisoning by systemic antibiotics
0.000 0.995 0.005
E14.0 With coma
0.005 0.995 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.995 0.005
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.005 0.995 0.000
H02.8 Other specified disorders of eyelid
0.000 0.995 0.005
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.995 0.005
I71.8 Aortic aneurysm of unspecified site, ruptured
0.005 0.995 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.005 0.995 0.000
T39.0 Salicylates
0.000 0.995 0.005
T40.5 Cocaine
0.000 0.995 0.005
I71.1 Thoracic aortic aneurysm, ruptured
0.005 0.995 0.000
T46.1 Calcium-channel blockers
0.000 0.995 0.005
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.995 0.005
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.995 0.005
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.995 0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.995 0.005
T50.1 Loop [high-ceiling] diuretics
0.000 0.995 0.005
T45.2 Vitamins, not elsewhere classified
0.000 0.995 0.005
S06.7 Intracranial injury with prolonged coma
0.000 0.995 0.005
T39.4 Antirheumatics, not elsewhere classified
0.000 0.995 0.005
T39.2 Pyrazolone derivatives
0.000 0.995 0.005
T42.4 Benzodiazepines
0.000 0.995 0.005
K62.6 Ulcer of anus and rectum
0.000 0.995 0.005
S06.4 Epidural haemorrhage
0.000 0.995 0.005
T50.8 Diagnostic agents
0.000 0.995 0.004
T50.7 Analeptics and opioid receptor antagonists
0.000 0.995 0.004
T50.5 Appetite depressants
0.000 0.995 0.004
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.995 0.004
T50.0 Mineralocorticoids and their antagonists
0.000 0.995 0.004
S06.9 Intracranial injury, unspecified
0.000 0.995 0.004
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.995 0.004
S06.8 Other intracranial injuries
0.000 0.995 0.004
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.996 0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.996 0.004
T40.8 Lysergide [LSD]
0.000 0.996 0.004
T40.7 Cannabis (derivatives)
0.000 0.996 0.004
T40.0 Opium
0.000 0.996 0.004
M54.56 Low back pain (Lumbar region)
0.004 0.996 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.004 0.996 0.000
S06.1 Traumatic cerebral oedema
0.000 0.996 0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.996 0.004
L40-L45 Papulosquamous disorders
0.000 0.996 0.004
T40.4 Other synthetic narcotics
0.000 0.996 0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.996 0.004
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.996 0.004
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.996 0.004
T40.3 Methadone
0.000 0.996 0.004
T40.1 Heroin
0.000 0.996 0.004
T36.0 Penicillins
0.000 0.996 0.004
S06.3 Focal brain injury
0.000 0.996 0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.996 0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.996 0.004
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.996 0.004
T46.7 Peripheral vasodilators
0.000 0.996 0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.996 0.004
T42.3 Barbiturates
0.000 0.996 0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.996 0.004
S06.0 Concussion
0.000 0.996 0.004
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.996 0.004
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.996 0.004
T36.3 Macrolides
0.000 0.996 0.004
S02.10 Fracture of base of skull (closed)
0.000 0.996 0.004
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.004 0.996 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.996 0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.004 0.996 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.996 0.004
S02 Fracture of skull and facial bones
0.000 0.996 0.004
S02.1 Fracture of base of skull
0.000 0.996 0.004
S02.60 Fracture of mandible (closed)
0.000 0.996 0.004
T45.5 Anticoagulants
0.000 0.996 0.004
I71.3 Abdominal aortic aneurysm, ruptured
0.004 0.996 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.996 0.004
S02.6 Fracture of mandible
0.000 0.996 0.004
T36.9 Systemic antibiotic, unspecified
0.000 0.996 0.004
T36.7 Antifungal antibiotics, systemically used
0.000 0.996 0.004
T36.6 Rifamycins
0.000 0.996 0.004
T36.5 Aminoglycosides
0.000 0.996 0.004
T36.4 Tetracyclines
0.000 0.996 0.004
T36.2 Chloramphenicol group
0.000 0.996 0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.996 0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.996 0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.996 0.004
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.996 0.004
T42.2 Succinimides and oxazolidinediones
0.000 0.996 0.004
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.000 0.996 0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.996 0.004
S72.00 Fracture of neck of femur (closed)
0.004 0.996 0.000
T43.6 Psychostimulants with abuse potential
0.000 0.996 0.004
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.003 0.996 0.000
T36.8 Other systemic antibiotics
0.000 0.996 0.004
S02.5 Fracture of tooth
0.000 0.996 0.004
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.996 0.004
T45.8 Other primarily systemic and haematological agents
0.000 0.996 0.004
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.996 0.004
T45.6 Fibrinolysis-affecting drugs
0.000 0.996 0.004
T45.4 Iron and its compounds
0.000 0.996 0.004
T45.3 Enzymes, not elsewhere classified
0.000 0.996 0.004
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.996 0.004
T48.5 Anti-common-cold drugs
0.000 0.996 0.004
T48.4 Expectorants
0.000 0.996 0.004
T48.3 Antitussives
0.000 0.996 0.004
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.996 0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.996 0.004
T48.0 Oxytocic drugs
0.000 0.996 0.004
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.003 0.996 0.000
M16.0 Primary coxarthrosis, bilateral
0.000 0.996 0.004
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.996 0.004
T49.9 Topical agent, unspecified
0.000 0.996 0.003
T49.8 Other topical agents
0.000 0.996 0.003
T49.7 Dental drugs, topically applied
0.000 0.996 0.003
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.996 0.003
T49.5 Ophthalmological drugs and preparations
0.000 0.996 0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.996 0.003
T49.3 Emollients, demulcents and protectants
0.000 0.996 0.003
T49.2 Local astringents and local detergents
0.000 0.996 0.003
T49.1 Antipruritics
0.000 0.996 0.003
S02.50 Fracture of tooth (closed)
0.000 0.996 0.004
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.996 0.003
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.996 0.003
T43.9 Psychotropic drug, unspecified
0.000 0.996 0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.996 0.003
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.996 0.003
T42.0 Hydantoin derivatives
0.000 0.996 0.003
L43 Lichen planus
0.000 0.996 0.004
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.000 0.996 0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.996 0.004
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.996 0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.996 0.003
L44 Other papulosquamous disorders
0.000 0.996 0.003
M54.94 Dorsalgia, unspecified (Thoracic region)
0.003 0.996 0.000
S02.2 Fracture of nasal bones
0.000 0.997 0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.997 0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.000 0.997 0.003
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.997 0.003
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.997 0.003
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.997 0.003
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.997 0.003
T42.1 Iminostilbenes
0.000 0.997 0.003
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.997 0.003
T47.4 Other laxatives
0.000 0.997 0.003
S02.3 Fracture of orbital floor
0.000 0.997 0.003
T41.5 Therapeutic gases
0.000 0.997 0.003
T41.4 Anaesthetic, unspecified
0.000 0.997 0.003
T41.3 Local anaesthetics
0.000 0.997 0.003
T41.1 Intravenous anaesthetics
0.000 0.997 0.003
T41.0 Inhaled anaesthetics
0.000 0.997 0.003
T40.6 Other and unspecified narcotics
0.000 0.997 0.003
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.000 0.997 0.003
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.997 0.003
K57.2 Diverticular disease of large intestine with perforation and abscess
0.000 0.997 0.003
S02.7 Multiple fractures involving skull and facial bones
0.000 0.997 0.003
S42.2 Fracture of upper end of humerus
0.003 0.997 0.000
L41 Parapsoriasis
0.000 0.997 0.003
D69.6 Thrombocytopenia, unspecified
0.000 0.997 0.003
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.997 0.003
S02.0 Fracture of vault of skull
0.000 0.997 0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.997 0.003
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.997 0.003
T47.7 Emetics
0.000 0.997 0.003
T47.5 Digestants
0.000 0.997 0.003
T47.3 Saline and osmotic laxatives
0.000 0.997 0.003
S06.01 Concussion (with open intracranial wound)
0.000 0.997 0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.997 0.003
T37.5 Antiviral drugs
0.000 0.997 0.003
T37.4 Anthelminthics
0.000 0.997 0.003
T37.3 Other antiprotozoal drugs
0.000 0.997 0.003
T37.1 Antimycobacterial drugs
0.000 0.997 0.003
T37.0 Sulphonamides
0.000 0.997 0.003
L43.9 Lichen planus, unspecified
0.000 0.997 0.003
T47.0 Histamine H(2)-receptor antagonists
0.000 0.997 0.003
H74.0 Tympanosclerosis
0.000 0.997 0.003
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.000 0.997 0.003
T47.6 Antidiarrhoeal drugs
0.000 0.997 0.003
T47.2 Stimulant laxatives
0.000 0.997 0.003
S02.11 Fracture of base of skull (open)
0.000 0.997 0.003
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.997 0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.997 0.003
T41.2 Other and unspecified general anaesthetics
0.000 0.997 0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.997 0.003
S02.61 Fracture of mandible (open)
0.000 0.997 0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.997 0.003
M54.59 Low back pain (Site unspecified)
0.003 0.997 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.997 0.003
L42 Pityriasis rosea
0.000 0.997 0.003
T38.9 Other and unspecified hormone antagonists
0.000 0.997 0.003
T38.7 Androgens and anabolic congeners
0.000 0.997 0.003
T38.4 Oral contraceptives
0.000 0.997 0.003
T38.2 Antithyroid drugs
0.000 0.997 0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.997 0.003
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.997 0.003
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.997 0.003
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.997 0.003
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.997 0.003
T44.0 Anticholinesterase agents
0.000 0.997 0.003
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.997 0.003
S02.20 Fracture of nasal bones (closed)
0.000 0.997 0.003
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.997 0.003
S02.51 Fracture of tooth (open)
0.000 0.997 0.003
S02.8 Fractures of other skull and facial bones
0.000 0.997 0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.997 0.003
T38.0 Glucocorticoids and synthetic analogues
0.000 0.997 0.003
A46 Erysipelas
0.000 0.997 0.003
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.997 0.003
S02.30 Fracture of orbital floor (closed)
0.000 0.997 0.003
E21.3 Hyperparathyroidism, unspecified
0.000 0.997 0.003
S02.21 Fracture of nasal bones (open)
0.000 0.997 0.003
Z11.5 Special screening examination for other viral diseases
0.000 0.997 0.003
L44.0 Pityriasis rubra pilaris
0.000 0.997 0.003
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.997 0.003
L43.3 Subacute (active) lichen planus
0.000 0.997 0.003
L43.2 Lichenoid drug reaction
0.000 0.997 0.003
L43.1 Bullous lichen planus
0.000 0.997 0.003
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.997 0.003
T38.5 Other oestrogens and progestogens
0.000 0.997 0.003
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.997 0.003
L44.9 Papulosquamous disorder, unspecified
0.000 0.997 0.003
L44.8 Other specified papulosquamous disorders
0.000 0.997 0.003
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.997 0.003
L44.3 Lichen ruber moniliformis
0.000 0.997 0.003
L44.2 Lichen striatus
0.000 0.997 0.003
L44.1 Lichen nitidus
0.000 0.997 0.003
T43.2 Other and unspecified antidepressants
0.000 0.997 0.003
L43.0 Hypertrophic lichen planus
0.000 0.997 0.003
S72.0 Fracture of neck of femur
0.003 0.997 0.000
S02.01 Fracture of vault of skull (open)
0.000 0.997 0.003
T38.1 Thyroid hormones and substitutes
0.000 0.997 0.002
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.997 0.002
S02.31 Fracture of orbital floor (open)
0.000 0.997 0.003
S42.21 Fracture of upper end of humerus (open)
0.002 0.997 0.000
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.997 0.002
S72.40 Fracture of lower end of femur (closed)
0.003 0.997 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.997 0.002
L41.8 Other parapsoriasis
0.000 0.997 0.002
L41.5 Retiform parapsoriasis
0.000 0.997 0.002
L41.4 Large plaque parapsoriasis
0.000 0.997 0.002
L41.3 Small plaque parapsoriasis
0.000 0.997 0.002
L41.2 Lymphomatoid papulosis
0.000 0.997 0.002
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.997 0.002
S06.00 Concussion (without open intracranial wound)
0.000 0.997 0.002
Q18.0 Sinus, fistula and cyst of branchial cleft
0.000 0.997 0.003
S02.00 Fracture of vault of skull (closed)
0.000 0.997 0.003
S02.4 Fracture of malar and maxillary bones
0.000 0.997 0.003
T45.0 Antiallergic and antiemetic drugs
0.000 0.997 0.002
N81.0 Female urethrocele
0.000 0.997 0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.997 0.002
I61.9 Intracerebral haemorrhage, unspecified
0.003 0.997 0.000
L41.1 Pityriasis lichenoides chronica
0.000 0.998 0.002
L43.8 Other lichen planus
0.000 0.998 0.002
T17.2 Foreign body in pharynx
0.000 0.998 0.002
H01.0 Blepharitis
0.002 0.998 0.000
N81 Female genital prolapse
0.000 0.998 0.002
S02.81 Fractures of other skull and facial bones (open)
0.000 0.998 0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.998 0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.998 0.002
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.998 0.002
A49.0 Staphylococcal infection, unspecified
0.000 0.998 0.002
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.998 0.002
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.998 0.002
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.002 0.998 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.998 0.002
C62.9 Testis, unspecified
0.002 0.998 0.000
H74 Other disorders of middle ear and mastoid
0.000 0.998 0.002
S72.01 Fracture of neck of femur (open)
0.002 0.998 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.998 0.002
E24.9 Cushing's syndrome, unspecified
0.000 0.998 0.002
M50-M54 Other dorsopathies
0.002 0.998 0.000
S72.4 Fracture of lower end of femur
0.002 0.998 0.000
E23.2 Diabetes insipidus
0.000 0.998 0.002
S72.30 Fracture of shaft of femur (closed)
0.002 0.998 0.000
K63.1 Perforation of intestine (nontraumatic)
0.000 0.998 0.002
M76.67 Achilles tendinitis (Ankle and foot)
0.002 0.998 0.000
E24 Cushing's syndrome
0.000 0.998 0.002
E27.1 Primary adrenocortical insufficiency
0.000 0.998 0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.998 0.002
E24.8 Other Cushing's syndrome
0.000 0.998 0.002
H25.9 Senile cataract, unspecified
0.000 0.998 0.002
S72.3 Fracture of shaft of femur
0.002 0.998 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.998 0.002
Z89.5 Acquired absence of leg at or below knee
0.002 0.998 0.000
H16 Keratitis
0.002 0.998 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.000 0.998 0.002
H16.2 Keratoconjunctivitis
0.002 0.998 0.000
O82.0 Delivery by elective Caesarean section
0.002 0.998 0.000
G24.9 Dystonia, unspecified
0.002 0.998 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.002 0.998 0.000
H16.0 Corneal ulcer
0.002 0.998 0.000
S72 Fracture of femur
0.002 0.998 0.000
H16.8 Other keratitis
0.002 0.998 0.000
H74.4 Polyp of middle ear
0.000 0.998 0.002
J94.2 Haemothorax
0.000 0.998 0.002
H20.0 Acute and subacute iridocyclitis
0.002 0.998 0.000
R30.9 Painful micturition, unspecified
0.000 0.998 0.002
C97 Malignant neoplasms of independent (primary) multiple sites
0.002 0.998 0.000
T31.0 Burns involving less than 10% of body surface
0.000 0.998 0.002
E24.0 Pituitary-dependent Cushing's disease
0.000 0.998 0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.002 0.998 0.000
Q18 Other congenital malformations of face and neck
0.000 0.998 0.002
M41.99 Scoliosis, unspecified (Site unspecified)
0.000 0.998 0.002
M79.09 Rheumatism, unspecified (Site unspecified)
0.002 0.998 0.000
A49.1 Streptococcal infection, unspecified
0.000 0.998 0.002
H74.1 Adhesive middle ear disease
0.000 0.998 0.002
Y52.1 Calcium-channel blockers
0.000 0.998 0.002
I61.3 Intracerebral haemorrhage in brain stem
0.002 0.998 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.998 0.002
E24.3 Ectopic ACTH syndrome
0.000 0.998 0.002
E24.1 Nelson's syndrome
0.000 0.998 0.002
S72.31 Fracture of shaft of femur (open)
0.002 0.998 0.000
H16.3 Interstitial and deep keratitis
0.002 0.998 0.000
O41.0 Oligohydramnios
0.002 0.998 0.000
O82.1 Delivery by emergency Caesarean section
0.002 0.998 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.998 0.002
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.998 0.002
H20.1 Chronic iridocyclitis
0.002 0.998 0.000
M76.6 Achilles tendinitis
0.002 0.998 0.000
S72.8 Fractures of other parts of femur
0.002 0.998 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.998 0.002
Z11.6 Special screening examination for other protozoal diseases and helminthiases
0.000 0.998 0.002
E21.4 Other specified disorders of parathyroid gland
0.000 0.998 0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.998 0.002
Z11.1 Special screening examination for respiratory tuberculosis
0.000 0.998 0.002
E25 Adrenogenital disorders
0.000 0.998 0.002
L29 Pruritus
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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