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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6461992
log Bayes Factor = 9.14097
Chromosome 7   position 27,220,831  (GRCh37) Explore rs6461992 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
T39.1 4-Aminophenol derivatives
0.318 0.682 0.000
I10-I15 Hypertensive diseases
0.000 0.707 0.293
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.290 0.710 0.000
T39.0 Salicylates
0.263 0.737 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.245 0.755 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.233 0.767 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.221 0.779 0.000
I13 Hypertensive heart and renal disease
0.000 0.790 0.210
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.208 0.792 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.208 0.792 0.000
T39.4 Antirheumatics, not elsewhere classified
0.208 0.792 0.000
T39.2 Pyrazolone derivatives
0.208 0.792 0.000
T45.0 Antiallergic and antiemetic drugs
0.200 0.800 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.200 0.800 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.200 0.800 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.197 0.803 0.000
I11 Hypertensive heart disease
0.000 0.804 0.196
T36 Poisoning by systemic antibiotics
0.193 0.807 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.190 0.810 0.000
T43.2 Other and unspecified antidepressants
0.188 0.812 0.000
I15 Secondary hypertension
0.000 0.814 0.186
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.185 0.815 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.178 0.822 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.176 0.824 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.176 0.824 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.176 0.824 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.176 0.824 0.000
I12 Hypertensive renal disease
0.000 0.824 0.176
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.173 0.827 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.171 0.829 0.000
T43.9 Psychotropic drug, unspecified
0.167 0.833 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.167 0.833 0.000
T43.6 Psychostimulants with abuse potential
0.167 0.833 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.167 0.833 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.165 0.835 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.165 0.835 0.000
T45.5 Anticoagulants
0.163 0.837 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.159 0.840 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.159 0.841 0.000
T45.8 Other primarily systemic and haematological agents
0.159 0.841 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.159 0.841 0.000
T45.6 Fibrinolysis-affecting drugs
0.159 0.841 0.000
T45.4 Iron and its compounds
0.159 0.841 0.000
T45.3 Enzymes, not elsewhere classified
0.159 0.841 0.000
T45.2 Vitamins, not elsewhere classified
0.159 0.841 0.000
T36.0 Penicillins
0.156 0.844 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.156 0.844 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.849 0.151
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.849 0.151
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.849 0.151
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.849 0.151
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.150 0.850 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.144 0.856 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.144 0.856 0.000
T46.7 Peripheral vasodilators
0.144 0.856 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.144 0.856 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.144 0.856 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.144 0.856 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.144 0.856 0.000
T46.1 Calcium-channel blockers
0.143 0.857 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.859 0.140
T36.9 Systemic antibiotic, unspecified
0.139 0.861 0.000
T36.8 Other systemic antibiotics
0.139 0.861 0.000
T36.7 Antifungal antibiotics, systemically used
0.139 0.861 0.000
T36.6 Rifamycins
0.139 0.861 0.000
T36.5 Aminoglycosides
0.139 0.861 0.000
T36.4 Tetracyclines
0.139 0.861 0.000
T36.3 Macrolides
0.139 0.861 0.000
T36.2 Chloramphenicol group
0.139 0.861 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.139 0.861 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.138 0.862 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.137 0.863 0.000
T38.9 Other and unspecified hormone antagonists
0.136 0.864 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.136 0.864 0.000
T38.7 Androgens and anabolic congeners
0.136 0.864 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.136 0.864 0.000
T38.5 Other oestrogens and progestogens
0.136 0.864 0.000
T38.4 Oral contraceptives
0.136 0.864 0.000
T38.2 Antithyroid drugs
0.136 0.864 0.000
T38.1 Thyroid hormones and substitutes
0.136 0.864 0.000
T38.0 Glucocorticoids and synthetic analogues
0.136 0.864 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.136 0.864 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.866 0.134
I15.8 Other secondary hypertension
0.000 0.866 0.134
I15.2 Hypertension secondary to endocrine disorders
0.000 0.866 0.134
I15.0 Renovascular hypertension
0.000 0.866 0.134
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.133 0.867 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.133 0.867 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.133 0.867 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.133 0.867 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.133 0.867 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.133 0.867 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.133 0.867 0.000
T44.0 Anticholinesterase agents
0.133 0.867 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.868 0.132
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.128 0.872 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.126 0.873 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.126 0.873 0.000
T37.5 Antiviral drugs
0.126 0.873 0.000
T37.4 Anthelminthics
0.126 0.873 0.000
T37.3 Other antiprotozoal drugs
0.126 0.873 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.126 0.873 0.000
T37.1 Antimycobacterial drugs
0.126 0.873 0.000
T37.0 Sulphonamides
0.126 0.873 0.000
T41.5 Therapeutic gases
0.126 0.873 0.000
T41.4 Anaesthetic, unspecified
0.126 0.873 0.000
T41.3 Local anaesthetics
0.126 0.873 0.000
T41.2 Other and unspecified general anaesthetics
0.126 0.873 0.000
T41.1 Intravenous anaesthetics
0.126 0.873 0.000
T41.0 Inhaled anaesthetics
0.126 0.873 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.126 0.873 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.126 0.873 0.000
T48.5 Anti-common-cold drugs
0.126 0.873 0.000
T48.4 Expectorants
0.126 0.873 0.000
T48.3 Antitussives
0.126 0.873 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.126 0.873 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.126 0.873 0.000
T48.0 Oxytocic drugs
0.126 0.873 0.000
T49.9 Topical agent, unspecified
0.126 0.873 0.000
T49.8 Other topical agents
0.126 0.873 0.000
T49.7 Dental drugs, topically applied
0.126 0.873 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.126 0.873 0.000
T49.5 Ophthalmological drugs and preparations
0.126 0.873 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.126 0.873 0.000
T49.3 Emollients, demulcents and protectants
0.126 0.873 0.000
T49.2 Local astringents and local detergents
0.126 0.873 0.000
T49.1 Antipruritics
0.126 0.873 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.126 0.873 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.874 0.126
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.121 0.879 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.118 0.881 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.118 0.881 0.000
T47.7 Emetics
0.118 0.881 0.000
T47.6 Antidiarrhoeal drugs
0.118 0.881 0.000
T47.5 Digestants
0.118 0.881 0.000
T47.4 Other laxatives
0.118 0.881 0.000
T47.3 Saline and osmotic laxatives
0.118 0.881 0.000
T47.2 Stimulant laxatives
0.118 0.881 0.000
T47.0 Histamine H(2)-receptor antagonists
0.118 0.881 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.887 0.112
T47.1 Other antacids and anti-gastric-secretion drugs
0.107 0.892 0.000
T50.8 Diagnostic agents
0.097 0.902 0.000
T50.7 Analeptics and opioid receptor antagonists
0.097 0.902 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.097 0.902 0.000
T50.5 Appetite depressants
0.097 0.902 0.000
T50.4 Drugs affecting uric acid metabolism
0.097 0.902 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.097 0.902 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.097 0.902 0.000
T50.1 Loop [high-ceiling] diuretics
0.097 0.902 0.000
T50.0 Mineralocorticoids and their antagonists
0.097 0.902 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.097 0.903 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.092 0.908 0.000
T40.8 Lysergide [LSD]
0.092 0.908 0.000
T40.7 Cannabis (derivatives)
0.092 0.908 0.000
T40.5 Cocaine
0.092 0.908 0.000
T40.3 Methadone
0.092 0.908 0.000
T40.1 Heroin
0.092 0.908 0.000
T40.0 Opium
0.092 0.908 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.087 0.913 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.087 0.913 0.000
T42.3 Barbiturates
0.087 0.913 0.000
T42.2 Succinimides and oxazolidinediones
0.087 0.913 0.000
T42.0 Hydantoin derivatives
0.087 0.913 0.000
T42.1 Iminostilbenes
0.087 0.913 0.000
T40.6 Other and unspecified narcotics
0.082 0.918 0.000
T40.4 Other synthetic narcotics
0.080 0.920 0.000
T40.2 Other opioids
0.078 0.922 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.925 0.075
I51.9 Heart disease, unspecified
0.000 0.931 0.069
I51 Complications and ill-defined descriptions of heart disease
0.000 0.935 0.065
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.059 0.941 0.000
I51.8 Other ill-defined heart diseases
0.000 0.941 0.059
T50.9 Other and unspecified drugs, medicaments and biological substances
0.057 0.942 0.001
I30-I52 Other forms of heart disease
0.000 0.943 0.057
I44.0 Atrioventricular block, first degree
0.000 0.943 0.057
I44 Atrioventricular and left bundle-branch block
0.000 0.944 0.056
Chapter IX Diseases of the circulatory system
0.000 0.944 0.056
T42.4 Benzodiazepines
0.054 0.946 0.000
I50 Heart failure
0.000 0.946 0.054
I51.7 Cardiomegaly
0.000 0.948 0.052
I05-I09 Chronic rheumatic heart diseases
0.000 0.948 0.052
I50.1 Left ventricular failure
0.000 0.949 0.051
I08 Multiple valve diseases
0.000 0.950 0.050
I51.6 Cardiovascular disease, unspecified
0.000 0.951 0.049
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.951 0.049
I35 Nonrheumatic aortic valve disorders
0.000 0.951 0.049
I44.3 Other and unspecified atrioventricular block
0.000 0.952 0.048
I35.0 Aortic (valve) stenosis
0.000 0.952 0.048
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.952 0.048
I51.5 Myocardial degeneration
0.000 0.953 0.047
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.953 0.047
Z95.0 Presence of cardiac pacemaker
0.000 0.953 0.047
I51.4 Myocarditis, unspecified
0.000 0.953 0.047
I50.9 Heart failure, unspecified
0.000 0.954 0.046
I37 Pulmonary valve disorders
0.000 0.955 0.045
I36 Nonrheumatic tricuspid valve disorders
0.000 0.955 0.045
I30 Acute pericarditis
0.000 0.955 0.045
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.956 0.044
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.956 0.044
I51.0 Cardiac septal defect, acquired
0.000 0.956 0.044
I45 Other conduction disorders
0.000 0.956 0.044
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.956 0.044
I44.6 Other and unspecified fascicular block
0.000 0.957 0.043
I44.2 Atrioventricular block, complete
0.000 0.958 0.042
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.041 0.959 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.959 0.041
I48 Atrial fibrillation and flutter
0.000 0.959 0.041
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.959 0.041
I41 Myocarditis in diseases classified elsewhere
0.000 0.959 0.041
I40 Acute myocarditis
0.000 0.959 0.041
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.959 0.041
I32 Pericarditis in diseases classified elsewhere
0.000 0.959 0.041
I44.5 Left posterior fascicular block
0.000 0.959 0.041
I44.4 Left anterior fascicular block
0.000 0.959 0.041
I00-I02 Acute rheumatic fever
0.000 0.960 0.040
I99 Other and unspecified disorders of circulatory system
0.000 0.960 0.040
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.961 0.039
I05 Rheumatic mitral valve diseases
0.000 0.961 0.039
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.961 0.039
I33 Acute and subacute endocarditis
0.000 0.962 0.038
I45.5 Other specified heart block
0.000 0.963 0.037
I06 Rheumatic aortic valve diseases
0.000 0.963 0.037
I08.9 Multiple valve disease, unspecified
0.000 0.964 0.036
I09 Other rheumatic heart diseases
0.000 0.964 0.036
I37.1 Pulmonary valve insufficiency
0.000 0.964 0.036
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.964 0.036
I30.9 Acute pericarditis, unspecified
0.000 0.964 0.035
M06.9 Rheumatoid arthritis, unspecified
0.035 0.965 0.000
I45.8 Other specified conduction disorders
0.000 0.966 0.034
I95 Hypotension
0.000 0.966 0.034
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.966 0.034
I35.9 Aortic valve disorder, unspecified
0.000 0.966 0.034
I45.3 Trifascicular block
0.000 0.966 0.034
I08.8 Other multiple valve diseases
0.000 0.967 0.033
I44.7 Left bundle-branch block, unspecified
0.000 0.967 0.033
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.033 0.967 0.000
I37.9 Pulmonary valve disorder, unspecified
0.000 0.968 0.032
I37.8 Other pulmonary valve disorders
0.000 0.968 0.032
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.968 0.032
I37.0 Pulmonary valve stenosis
0.000 0.968 0.032
I50.0 Congestive heart failure
0.000 0.968 0.032
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.968 0.032
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.968 0.032
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.968 0.032
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.968 0.032
I30.8 Other forms of acute pericarditis
0.000 0.968 0.032
I30.1 Infective pericarditis
0.000 0.968 0.032
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.968 0.032
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.968 0.032
I45.2 Bifascicular block
0.000 0.968 0.032
I45.0 Right fascicular block
0.000 0.968 0.032
I45.4 Nonspecific intraventricular block
0.000 0.968 0.032
I05.0 Mitral stenosis
0.000 0.969 0.031
I45.9 Conduction disorder, unspecified
0.000 0.969 0.031
I45.1 Other and unspecified right bundle-branch block
0.000 0.969 0.031
I05.2 Mitral stenosis with insufficiency
0.000 0.969 0.030
I35.8 Other aortic valve disorders
0.000 0.970 0.030
I95.9 Hypotension, unspecified
0.000 0.970 0.030
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.970 0.030
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.970 0.030
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.970 0.030
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.970 0.030
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.970 0.030
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.970 0.030
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.970 0.030
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.970 0.030
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.970 0.030
I40.9 Acute myocarditis, unspecified
0.000 0.970 0.030
I40.8 Other acute myocarditis
0.000 0.970 0.030
I40.1 Isolated myocarditis
0.000 0.970 0.030
I40.0 Infective myocarditis
0.000 0.970 0.030
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.970 0.030
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.970 0.030
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.970 0.030
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.970 0.030
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.970 0.030
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.970 0.030
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.970 0.030
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.970 0.030
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.970 0.030
I48.4 Atypical atrial flutter
0.000 0.970 0.030
I48.3 Typical atrial flutter
0.000 0.970 0.030
I48.2 Chronic atrial fibrillation
0.000 0.970 0.030
I48.1 Persistent atrial fibrillation
0.000 0.970 0.030
I48.0 Paroxysmal atrial fibrillation
0.000 0.970 0.030
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.970 0.030
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.970 0.030
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.970 0.030
I08.0 Disorders of both mitral and aortic valves
0.000 0.970 0.030
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.029 0.971 0.000
I02 Rheumatic chorea
0.000 0.971 0.029
I01 Rheumatic fever with heart involvement
0.000 0.971 0.029
I00 Rheumatic fever without mention of heart involvement
0.000 0.971 0.029
I05.1 Rheumatic mitral insufficiency
0.000 0.971 0.029
I35.1 Aortic (valve) insufficiency
0.000 0.971 0.029
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.029 0.971 0.000
I05.8 Other mitral valve diseases
0.000 0.972 0.028
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.972 0.028
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.972 0.028
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.972 0.028
I98.0 Cardiovascular syphilis
0.000 0.972 0.028
I33.9 Acute endocarditis, unspecified
0.000 0.972 0.027
I07 Rheumatic tricuspid valve diseases
0.000 0.973 0.027
I46 Cardiac arrest
0.000 0.973 0.027
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.973 0.027
I06.8 Other rheumatic aortic valve diseases
0.000 0.973 0.027
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.973 0.027
I06.1 Rheumatic aortic insufficiency
0.000 0.973 0.027
I06.0 Rheumatic aortic stenosis
0.000 0.973 0.027
I38 Endocarditis, valve unspecified
0.000 0.974 0.026
I09.8 Other specified rheumatic heart diseases
0.000 0.974 0.026
I09.2 Chronic rheumatic pericarditis
0.000 0.974 0.026
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.974 0.026
I09.0 Rheumatic myocarditis
0.000 0.974 0.026
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.974 0.026
I44.1 Atrioventricular block, second degree
0.000 0.974 0.026
I45.6 Preexcitation syndrome
0.000 0.974 0.026
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.025 0.975 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.025 0.975 0.000
I09.9 Rheumatic heart disease, unspecified
0.000 0.975 0.025
I95.8 Other hypotension
0.000 0.975 0.025
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.975 0.025
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.975 0.025
I97.0 Postcardiotomy syndrome
0.000 0.975 0.025
I33.0 Acute and subacute infective endocarditis
0.000 0.975 0.024
I47 Paroxysmal tachycardia
0.000 0.975 0.024
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.976 0.024
F32 Depressive episode
0.024 0.976 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.023 0.977 0.000
F32.9 Depressive episode, unspecified
0.023 0.977 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.977 0.023
I95.2 Hypotension due to drugs
0.000 0.977 0.023
I97.1 Other functional disturbances following cardiac surgery
0.000 0.977 0.023
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.023 0.977 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.022 0.977 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.022 0.978 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.978 0.022
I95.0 Idiopathic hypotension
0.000 0.978 0.022
F32.2 Severe depressive episode without psychotic symptoms
0.022 0.978 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.022 0.978 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.979 0.021
I01.8 Other acute rheumatic heart disease
0.000 0.979 0.021
I01.2 Acute rheumatic myocarditis
0.000 0.979 0.021
I01.1 Acute rheumatic endocarditis
0.000 0.979 0.021
I01.0 Acute rheumatic pericarditis
0.000 0.979 0.021
I02.9 Rheumatic chorea without heart involvement
0.000 0.979 0.021
I02.0 Rheumatic chorea with heart involvement
0.000 0.979 0.021
I07.9 Tricuspid valve disease, unspecified
0.000 0.980 0.019
I07.8 Other tricuspid valve diseases
0.000 0.980 0.019
I07.2 Tricuspid stenosis with insufficiency
0.000 0.980 0.019
I07.0 Tricuspid stenosis
0.000 0.980 0.019
I46.1 Sudden cardiac death, so described
0.000 0.980 0.020
I95.1 Orthostatic hypotension
0.000 0.980 0.020
I31 Other diseases of pericardium
0.001 0.981 0.018
I42 Cardiomyopathy
0.000 0.981 0.019
R47.8 Other and unspecified speech disturbances
0.019 0.981 0.000
F32.0 Mild depressive episode
0.018 0.982 0.000
F32.8 Other depressive episodes
0.018 0.982 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.982 0.018
F30-F39 Mood [affective] disorders
0.018 0.982 0.000
M06 Other rheumatoid arthritis
0.017 0.983 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.983 0.017
I46.9 Cardiac arrest, unspecified
0.000 0.984 0.016
F33 Recurrent depressive disorder
0.016 0.984 0.000
I47.2 Ventricular tachycardia
0.000 0.984 0.016
I28 Other diseases of pulmonary vessels
0.000 0.984 0.015
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.000 0.985 0.015
F31 Bipolar affective disorder
0.015 0.985 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.985 0.015
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.015 0.985 0.000
M06.3 Rheumatoid nodule
0.014 0.985 0.000
F33.9 Recurrent depressive disorder, unspecified
0.014 0.986 0.000
I42.6 Alcoholic cardiomyopathy
0.000 0.986 0.014
Z95.1 Presence of aortocoronary bypass graft
0.000 0.986 0.014
I31.8 Other specified diseases of pericardium
0.001 0.986 0.013
I31.2 Haemopericardium, not elsewhere classified
0.001 0.986 0.013
I31.1 Chronic constrictive pericarditis
0.001 0.986 0.013
I31.0 Chronic adhesive pericarditis
0.001 0.986 0.013
I49 Other cardiac arrhythmias
0.000 0.986 0.014
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.986 0.014
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.986 0.014
I42.5 Other restrictive cardiomyopathy
0.000 0.986 0.014
I42.4 Endocardial fibroelastosis
0.000 0.986 0.014
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.986 0.014
I42.2 Other hypertrophic cardiomyopathy
0.000 0.986 0.014
F32.1 Moderate depressive episode
0.013 0.986 0.000
M47.82 Other spondylosis (Cervical region)
0.013 0.987 0.000
I42.0 Dilated cardiomyopathy
0.000 0.987 0.013
F31.0 Bipolar affective disorder, current episode hypomanic
0.013 0.987 0.000
F38 Other mood [affective] disorders
0.013 0.987 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.013 0.987 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.012 0.988 0.000
M06.8 Other specified rheumatoid arthritis
0.012 0.988 0.000
M06.2 Rheumatoid bursitis
0.012 0.988 0.000
M06.1 Adult-onset Still's disease
0.012 0.988 0.000
F34 Persistent mood [affective] disorders
0.012 0.988 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.012 0.988 0.000
I27 Other pulmonary heart diseases
0.000 0.988 0.012
F39 Unspecified mood [affective] disorder
0.012 0.988 0.000
M06.4 Inflammatory polyarthropathy
0.012 0.988 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.012 0.988 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.000 0.988 0.012
I46.0 Cardiac arrest with successful resuscitation
0.000 0.988 0.012
F31.9 Bipolar affective disorder, unspecified
0.012 0.988 0.000
F33.8 Other recurrent depressive disorders
0.012 0.988 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.012 0.988 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.012 0.988 0.000
Z95.4 Presence of other heart-valve replacement
0.000 0.988 0.012
F30 Manic episode
0.011 0.988 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.000 0.988 0.012
F33.0 Recurrent depressive disorder, current episode mild
0.011 0.988 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.988 0.011
I28.1 Aneurysm of pulmonary artery
0.000 0.988 0.011
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.988 0.011
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.011 0.989 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.000 0.989 0.011
F31.8 Other bipolar affective disorders
0.011 0.989 0.000
F31.7 Bipolar affective disorder, currently in remission
0.011 0.989 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.011 0.989 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.989 0.011
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.989 0.011
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.011 0.989 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.011 0.989 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.989 0.011
I49.5 Sick sinus syndrome
0.000 0.989 0.011
M06.39 Rheumatoid nodule (Site unspecified)
0.011 0.989 0.000
M06.38 Rheumatoid nodule (Other)
0.011 0.989 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.011 0.989 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.011 0.989 0.000
M06.33 Rheumatoid nodule (Forearm)
0.011 0.989 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.011 0.989 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.011 0.989 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.990 0.010
I42.8 Other cardiomyopathies
0.000 0.990 0.010
I49.2 Junctional premature depolarisation
0.000 0.990 0.010
I49.0 Ventricular fibrillation and flutter
0.000 0.990 0.010
Z95.2 Presence of prosthetic heart valve
0.000 0.990 0.010
M06.34 Rheumatoid nodule (Hand)
0.010 0.990 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.010 0.990 0.000
I07.1 Tricuspid insufficiency
0.001 0.990 0.009
I49.9 Cardiac arrhythmia, unspecified
0.000 0.990 0.010
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.000 0.990 0.010
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.990 0.009
F38.8 Other specified mood [affective] disorders
0.009 0.990 0.000
F38.1 Other recurrent mood [affective] disorders
0.009 0.990 0.000
F38.0 Other single mood [affective] disorders
0.009 0.990 0.000
M06.0 Seronegative rheumatoid arthritis
0.009 0.990 0.000
I60-I69 Cerebrovascular diseases
0.000 0.991 0.009
I49.1 Atrial premature depolarisation
0.000 0.991 0.009
I31.3 Pericardial effusion (noninflammatory)
0.001 0.991 0.009
I42.9 Cardiomyopathy, unspecified
0.000 0.991 0.009
M06.19 Adult-onset Still's disease (Site unspecified)
0.009 0.991 0.000
M06.18 Adult-onset Still's disease (Other)
0.009 0.991 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.009 0.991 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.009 0.991 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.009 0.991 0.000
M06.14 Adult-onset Still's disease (Hand)
0.009 0.991 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.009 0.991 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.009 0.991 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.009 0.991 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.009 0.991 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.009 0.991 0.000
M06.28 Rheumatoid bursitis (Other)
0.009 0.991 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.009 0.991 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.009 0.991 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.009 0.991 0.000
M06.24 Rheumatoid bursitis (Hand)
0.009 0.991 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.009 0.991 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.009 0.991 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.009 0.991 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.009 0.991 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.009 0.991 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.009 0.991 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.009 0.991 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.009 0.991 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.009 0.991 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.009 0.991 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.009 0.991 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.009 0.991 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.009 0.991 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.009 0.991 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.009 0.991 0.000
F34.8 Other persistent mood [affective] disorders
0.009 0.991 0.000
F34.0 Cyclothymia
0.009 0.991 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.991 0.009
I27.1 Kyphoscoliotic heart disease
0.000 0.991 0.009
I27.0 Primary pulmonary hypertension
0.000 0.991 0.009
M06.48 Inflammatory polyarthropathy (Other)
0.009 0.991 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.009 0.991 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.009 0.991 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.009 0.991 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.009 0.991 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.009 0.991 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.009 0.991 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.009 0.991 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.009 0.991 0.000
I26 Pulmonary embolism
0.000 0.991 0.009
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.000 0.991 0.009
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.000 0.991 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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