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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs652888
log Bayes Factor = 121.496
Chromosome 6   position 31,851,234  (GRCh37) Explore rs652888 on Ensembl!
Variant rs652888 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E11.3 With ophthalmic complications
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
K75 Other inflammatory liver diseases
0.998 0.002 0.000
E14.3 With ophthalmic complications
0.998 0.002 0.000
M07.3 Other psoriatic arthropathies
0.998 0.002 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.997 0.003 0.000
E14.9 Without complications
0.996 0.004 0.000
M07 Psoriatic and enteropathic arthropathies
0.995 0.005 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
B37 Candidiasis
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
B35-B49 Mycoses
0.994 0.006 0.000
K75.4 Autoimmune hepatitis
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.992 0.008 0.000
Chapter XI Diseases of the digestive system
0.992 0.008 0.000
C83.3 Large cell (diffuse)
0.989 0.011 0.000
E70-E90 Metabolic disorders
0.988 0.012 0.000
H34 Retinal vascular occlusions
0.987 0.013 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.986 0.014 0.000
E89.0 Postprocedural hypothyroidism
0.985 0.015 0.000
K75.8 Other specified inflammatory liver diseases
0.985 0.015 0.000
E20-E35 Disorders of other endocrine glands
0.985 0.015 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.985 0.015 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.984 0.016 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
N00-N08 Glomerular diseases
0.981 0.019 0.000
N04 Nephrotic syndrome
0.981 0.019 0.000
M20-M25 Other joint disorders
0.980 0.019 0.000
E11.1 With ketoacidosis
0.980 0.020 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.980 0.020 0.000
E10.2 With renal complications
0.980 0.020 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.979 0.021 0.000
N04.9 Unspecified
0.978 0.022 0.000
M35 Other systemic involvement of connective tissue
0.975 0.025 0.000
M35.0 Sicca syndrome [Sjogren]
0.975 0.025 0.000
B37.0 Candidal stomatitis
0.975 0.025 0.000
E10.4 With neurological complications
0.974 0.026 0.000
B37.8 Candidiasis of other sites
0.974 0.026 0.000
M20.1 Hallux valgus (acquired)
0.000 0.027 0.973
H34.8 Other retinal vascular occlusions
0.972 0.028 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.971 0.029 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.971 0.029 0.000
E11.9 Without complications
0.970 0.030 0.000
K74 Fibrosis and cirrhosis of liver
0.969 0.031 0.000
D70 Agranulocytosis
0.968 0.032 0.000
E88 Other metabolic disorders
0.968 0.032 0.000
E27 Other disorders of adrenal gland
0.966 0.034 0.000
E27.1 Primary adrenocortical insufficiency
0.965 0.035 0.000
B37.9 Candidiasis, unspecified
0.964 0.036 0.000
L50-L54 Urticaria and erythema
0.963 0.037 0.000
K73 Chronic hepatitis, not elsewhere classified
0.961 0.039 0.000
N05 Unspecified nephritic syndrome
0.958 0.042 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.955 0.045 0.000
K74.6 Other and unspecified cirrhosis of liver
0.955 0.045 0.000
C85.1 B-cell lymphoma, unspecified
0.951 0.049 0.000
Chapter II Neoplasms
0.949 0.051 0.000
G62 Other polyneuropathies
0.949 0.051 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.948 0.052 0.000
M20 Acquired deformities of fingers and toes
0.000 0.055 0.945
D61 Other aplastic anaemias
0.944 0.056 0.000
E50-E64 Other nutritional deficiencies
0.943 0.057 0.000
L10-L14 Bullous disorders
0.942 0.058 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.942 0.058 0.000
G62.9 Polyneuropathy, unspecified
0.939 0.061 0.000
N05.2 Diffuse membranous glomerulonephritis
0.936 0.064 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.935 0.065 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.933 0.067 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.933 0.067 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.932 0.068 0.000
C91 Lymphoid leukaemia
0.932 0.068 0.000
L52 Erythema nodosum
0.931 0.069 0.000
E24 Cushing's syndrome
0.930 0.070 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.072 0.928
G51 Facial nerve disorders
0.923 0.077 0.000
C34 Malignant neoplasm of bronchus and lung
0.921 0.079 0.000
B15-B19 Viral hepatitis
0.919 0.081 0.000
E53 Deficiency of other B group vitamins
0.904 0.096 0.000
E14.1 With ketoacidosis
0.903 0.097 0.000
L13 Other bullous disorders
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.899 0.101 0.000
D61.9 Aplastic anaemia, unspecified
0.895 0.105 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.892 0.108 0.000
C81 Hodgkin's disease
0.890 0.109 0.000
K70 Alcoholic liver disease
0.890 0.110 0.000
B07 Viral warts
0.887 0.113 0.000
K40-K46 Hernia
0.884 0.116 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.884 0.116 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.882 0.118 0.000
B18 Chronic viral hepatitis
0.881 0.119 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.881 0.119 0.000
E53.8 Deficiency of other specified B group vitamins
0.876 0.124 0.000
B36 Other superficial mycoses
0.876 0.124 0.000
L13.0 Dermatitis herpetiformis
0.875 0.125 0.000
K73.9 Chronic hepatitis, unspecified
0.875 0.125 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.875 0.125 0.000
H46 Optic neuritis
0.875 0.125 0.000
M60-M63 Disorders of muscles
0.874 0.126 0.000
M24 Other specific joint derangements
0.874 0.126 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.873 0.127 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.872 0.128 0.000
C91.1 Chronic lymphocytic leukaemia
0.870 0.130 0.000
C34.3 Lower lobe, bronchus or lung
0.870 0.130 0.000
E10.5 With peripheral circulatory complications
0.868 0.132 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.867 0.133 0.000
E24.0 Pituitary-dependent Cushing's disease
0.866 0.134 0.000
K72 Hepatic failure, not elsewhere classified
0.866 0.134 0.000
C34.2 Middle lobe, bronchus or lung
0.863 0.137 0.000
E11.5 With peripheral circulatory complications
0.861 0.139 0.000
M34 Systemic sclerosis
0.861 0.139 0.000
E14.8 With unspecified complications
0.861 0.139 0.000
E10.0 With coma
0.861 0.139 0.000
L40.1 Generalised pustular psoriasis
0.858 0.142 0.000
L89 Decubitus ulcer
0.857 0.143 0.000
G30-G32 Other degenerative diseases of the nervous system
0.856 0.144 0.000
B25-B34 Other viral diseases
0.855 0.145 0.000
N04.1 Focal and segmental glomerular lesions
0.854 0.146 0.000
B18.2 Chronic viral hepatitis C
0.844 0.156 0.000
M14 Arthropathies in other diseases classified elsewhere
0.843 0.157 0.000
M86-M90 Other osteopathies
0.843 0.157 0.000
K45 Other abdominal hernia
0.842 0.158 0.000
H47.2 Optic atrophy
0.841 0.159 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.840 0.160 0.000
E73 Lactose intolerance
0.840 0.160 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.840 0.160 0.000
K43 Ventral hernia
0.840 0.160 0.000
N05.1 Focal and segmental glomerular lesions
0.840 0.160 0.000
D73 Diseases of spleen
0.839 0.161 0.000
G51.9 Disorder of facial nerve, unspecified
0.836 0.164 0.000
L84 Corns and callosities
0.836 0.164 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.832 0.168 0.000
G61 Inflammatory polyneuropathy
0.832 0.168 0.000
H30 Chorioretinal inflammation
0.832 0.168 0.000
D55-D59 Haemolytic anaemias
0.831 0.169 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.829 0.171 0.000
E21.3 Hyperparathyroidism, unspecified
0.828 0.172 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.828 0.172 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.827 0.173 0.000
D69 Purpura and other haemorrhagic conditions
0.825 0.175 0.000
E11.6 With other specified complications
0.824 0.176 0.000
G51.0 Bell's palsy
0.824 0.176 0.000
C92 Myeloid leukaemia
0.822 0.178 0.000
E14.5 With peripheral circulatory complications
0.822 0.178 0.000
L93 Lupus erythematosus
0.821 0.179 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.181 0.819
G56.4 Causalgia
0.819 0.181 0.000
M22 Disorders of patella
0.818 0.182 0.000
N04.2 Diffuse membranous glomerulonephritis
0.818 0.182 0.000
E10.6 With other specified complications
0.815 0.185 0.000
G70-G73 Diseases of myoneural junction and muscle
0.813 0.187 0.000
C38.4 Pleura
0.812 0.188 0.000
E10.8 With unspecified complications
0.809 0.191 0.000
E88.2 Lipomatosis, not elsewhere classified
0.808 0.192 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.807 0.193 0.000
K70.4 Alcoholic hepatic failure
0.806 0.194 0.000
Q00-Q07 Congenital malformations of the nervous system
0.805 0.195 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.804 0.196 0.000
D72 Other disorders of white blood cells
0.804 0.196 0.000
E10.7 With multiple complications
0.803 0.197 0.000
C88 Malignant immunoproliferative diseases
0.801 0.199 0.000
G59.0 Diabetic mononeuropathy
0.801 0.199 0.000
E28 Ovarian dysfunction
0.800 0.200 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.800 0.200 0.000
M35.7 Hypermobility syndrome
0.799 0.201 0.000
M86 Osteomyelitis
0.799 0.201 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.798 0.202 0.000
C91.9 Lymphoid leukaemia, unspecified
0.795 0.205 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.795 0.205 0.000
L92.0 Granuloma annulare
0.794 0.206 0.000
B00 Herpesviral [herpes simplex] infections
0.794 0.206 0.000
K74.0 Hepatic fibrosis
0.794 0.206 0.000
L40.3 Pustulosis palmaris et plantaris
0.793 0.207 0.000
B36.9 Superficial mycosis, unspecified
0.792 0.208 0.000
G56.1 Other lesions of median nerve
0.790 0.210 0.000
L89.2 Stage III decubitus ulcer
0.790 0.210 0.000
E24.2 Drug-induced Cushing's syndrome
0.790 0.210 0.000
K50-K52 Noninfective enteritis and colitis
0.788 0.211 0.001
E11.2 With renal complications
0.788 0.212 0.000
C34.9 Bronchus or lung, unspecified
0.788 0.212 0.000
C15-C26 Malignant neoplasms of digestive organs
0.787 0.213 0.000
L43 Lichen planus
0.787 0.213 0.000
L40.0 Psoriasis vulgaris
0.786 0.214 0.000
E31 Polyglandular dysfunction
0.786 0.214 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.785 0.215 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.783 0.217 0.000
L94 Other localised connective tissue disorders
0.782 0.218 0.000
K71 Toxic liver disease
0.780 0.219 0.000
H47.3 Other disorders of optic disk
0.779 0.221 0.000
M00-M03 Infectious arthropathies
0.779 0.221 0.000
G64 Other disorders of peripheral nervous system
0.778 0.222 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.777 0.223 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.776 0.224 0.000
K52 Other non-infective gastro-enteritis and colitis
0.776 0.224 0.000
B37.1 Pulmonary candidiasis
0.775 0.225 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.775 0.225 0.000
M32 Systemic lupus erythematosus
0.775 0.225 0.000
M24.1 Other articular cartilage disorders
0.775 0.225 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.775 0.225 0.000
H34.2 Other retinal artery occlusions
0.775 0.225 0.000
K76 Other diseases of liver
0.773 0.227 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.773 0.227 0.000
E74 Other disorders of carbohydrate metabolism
0.773 0.227 0.000
G61.0 Guillain-Barre syndrome
0.773 0.227 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.772 0.228 0.000
D69.6 Thrombocytopenia, unspecified
0.772 0.228 0.000
E51 Thiamine deficiency
0.771 0.229 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.771 0.229 0.000
E14.2 Withrenal complications
0.770 0.230 0.000
C81.1 Nodular sclerosis
0.770 0.230 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.769 0.231 0.000
E13 Other specified diabetes mellitus
0.769 0.231 0.000
L50 Urticaria
0.768 0.232 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.233 0.767
M20.4 Other hammer toe(s) (acquired)
0.000 0.234 0.766
E07 Other disorders of thyroid
0.766 0.234 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.765 0.235 0.000
N03 Chronic nephritic syndrome
0.764 0.235 0.000
C20 Malignant neoplasm of rectum
0.762 0.238 0.000
K70.3 Alcoholic cirrhosis of liver
0.760 0.240 0.000
M21 Other acquired deformities of limbs
0.759 0.241 0.000
M33 Dermatopolymyositis
0.759 0.241 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.756 0.244 0.000
M35.1 Other overlap syndromes
0.754 0.245 0.000
H47.1 Papilloedema, unspecified
0.754 0.246 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.753 0.246 0.000
E88.8 Other specified metabolic disorders
0.752 0.247 0.000
C04 Malignant neoplasm of floor of mouth
0.752 0.248 0.000
B37.7 Candidal septicaemia
0.752 0.248 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.752 0.248 0.000
E14.4 With neurological complications
0.750 0.250 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.750 0.250 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.749 0.251 0.000
H34.9 Retinal vascular occlusion, unspecified
0.747 0.253 0.000
B01 Varicella [chickenpox]
0.747 0.253 0.000
G52 Disorders of other cranial nerves
0.746 0.254 0.000
C95 Leukaemia of unspecified cell type
0.745 0.255 0.000
L42 Pityriasis rosea
0.744 0.255 0.000
B34 Viral infection of unspecified site
0.744 0.256 0.000
M60 Myositis
0.743 0.257 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.739 0.261 0.000
K90-K93 Other diseases of the digestive system
0.737 0.263 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.736 0.264 0.000
D59 Acquired haemolytic anaemia
0.736 0.264 0.000
H34.1 Central retinal artery occlusion
0.736 0.264 0.000
E73.9 Lactose intolerance, unspecified
0.734 0.266 0.000
K72.0 Acute and subacute hepatic failure
0.734 0.266 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.734 0.266 0.000
C83.1 Small cleaved cell (diffuse)
0.733 0.267 0.000
K76.8 Other specified diseases of liver
0.733 0.267 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.733 0.267 0.000
Q60-Q64 Congenital malformations of the urinary system
0.732 0.268 0.000
C81.9 Hodgkin's disease, unspecified
0.730 0.270 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.730 0.270 0.000
H55-H59 Other disorders of eye and adnexa
0.729 0.271 0.000
C92.0 Acute myeloid leukaemia
0.729 0.271 0.000
G62.1 Alcoholic polyneuropathy
0.729 0.271 0.000
H31 Other disorders of choroid
0.728 0.272 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.727 0.272 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.727 0.273 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.727 0.273 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.726 0.273 0.000
L51 Erythema multiforme
0.725 0.275 0.000
B00.9 Herpesviral infection, unspecified
0.725 0.275 0.000
L95.8 Other vasculitis limited to skin
0.722 0.278 0.000
C83.0 Small cell (diffuse)
0.722 0.278 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.721 0.279 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.721 0.279 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.720 0.279 0.000
K90 Intestinal malabsorption
0.720 0.280 0.000
E03.8 Other specified hypothyroidism
0.719 0.281 0.000
N00 Acute nephritic syndrome
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
L44 Other papulosquamous disorders
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.716 0.284 0.000
C94 Other leukaemias of specified cell type
0.716 0.284 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.716 0.284 0.000
C34.0 Main bronchus
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
K75.2 Nonspecific reactive hepatitis
0.716 0.284 0.000
K75.1 Phlebitis of portal vein
0.716 0.284 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.716 0.284 0.000
M07.38 Other psoriatic arthropathies (Other)
0.715 0.285 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.715 0.285 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.715 0.285 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.715 0.285 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.715 0.285 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
E06 Thyroiditis
0.714 0.286 0.000
M21.0 Valgus deformity, not elsewhere classified
0.714 0.286 0.000
D73.5 Infarction of spleen
0.714 0.286 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.714 0.286 0.000
D50-D53 Nutritional anaemias
0.713 0.287 0.000
M07.6 Other enteropathic arthropathies
0.713 0.287 0.000
M07.5 Arthropathy in ulcerative colitis
0.713 0.287 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.713 0.287 0.000
M07.2 Psoriatic spondylitis
0.713 0.287 0.000
M07.1 Arthritis mutilans
0.713 0.287 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
B37.6 Candidal endocarditis
0.713 0.287 0.000
B37.5 Candidal meningitis
0.713 0.287 0.000
M62 Other disorders of muscle
0.713 0.287 0.000
B48 Other mycoses, not elsewhere classified
0.713 0.287 0.000
B47 Mycetoma
0.713 0.287 0.000
B46 Zygomycosis
0.713 0.287 0.000
B45 Cryptococcosis
0.713 0.287 0.000
B43 Chromomycosis and phaeomycotic abscess
0.713 0.287 0.000
B42 Sporotrichosis
0.713 0.287 0.000
B41 Paracoccidioidomycosis
0.713 0.287 0.000
B40 Blastomycosis
0.713 0.287 0.000
B39 Histoplasmosis
0.713 0.287 0.000
B38 Coccidioidomycosis
0.713 0.287 0.000
M24.0 Loose body in joint
0.712 0.288 0.000
H30.9 Chorioretinal inflammation, unspecified
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
C83.6 Undifferentiated (diffuse)
0.711 0.289 0.000
C83.5 Lymphoblastic (diffuse)
0.711 0.289 0.000
C83.4 Immunoblastic (diffuse)
0.711 0.289 0.000
C83.2 Mixed small and large cell (diffuse)
0.711 0.289 0.000
L80 Vitiligo
0.710 0.290 0.000
K70.1 Alcoholic hepatitis
0.710 0.290 0.000
E84 Cystic fibrosis
0.708 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.291 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
M14.6 Neuropathic arthropathy
0.708 0.292 0.000
H34.0 Transient retinal artery occlusion
0.708 0.292 0.000
C86 Other specified types of T/NK-cell lymphoma
0.707 0.293 0.000
C91.0 Acute lymphoblastic leukaemia
0.707 0.293 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.706 0.294 0.000
E32 Diseases of thymus
0.706 0.294 0.000
E30 Disorders of puberty, not elsewhere classified
0.706 0.294 0.000
E25 Adrenogenital disorders
0.706 0.294 0.000
E40-E46 Malnutrition
0.706 0.294 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.706 0.294 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.706 0.294 0.000
E89.5 Postprocedural testicular hypofunction
0.706 0.294 0.000
E89.4 Postprocedural ovarian failure
0.706 0.294 0.000
E89.1 Postprocedural hypoinsulinaemia
0.706 0.294 0.000
D74 Methaemoglobinaemia
0.706 0.294 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.706 0.294 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.706 0.294 0.000
N04.8 Other
0.703 0.297 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.703 0.297 0.000
N04.6 Dense deposit disease
0.703 0.297 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.703 0.297 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.703 0.297 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.703 0.297 0.000
N04.0 Minor glomerular abnormality
0.703 0.297 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.703 0.297 0.000
N06 Isolated proteinuria with specified morphological lesion
0.703 0.297 0.000
N01 Rapidly progressive nephritic syndrome
0.703 0.297 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.702 0.298 0.000
N05.8 Other
0.702 0.298 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.702 0.298 0.000
D61.1 Drug-induced aplastic anaemia
0.701 0.299 0.000
M12 Other specific arthropathies
0.700 0.300 0.000
L50.0 Allergic urticaria
0.700 0.300 0.000
M11 Other crystal arthropathies
0.699 0.301 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.699 0.301 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.699 0.301 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.699 0.301 0.000
M35.5 Multifocal fibrosclerosis
0.699 0.301 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.699 0.301 0.000
B25 Cytomegaloviral disease
0.699 0.301 0.000
M22.3 Other derangements of patella
0.698 0.302 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.698 0.302 0.000
D61.0 Constitutional aplastic anaemia
0.698 0.302 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.698 0.302 0.000
D69.2 Other nonthrombocytopenic purpura
0.698 0.302 0.000
C34.8 Overlapping lesion of bronchus and lung
0.697 0.302 0.000
H06.2 Dysthyroid exophthalmos
0.696 0.304 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.696 0.304 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.696 0.304 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.696 0.304 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.696 0.304 0.000
C38.3 Mediastinum, part unspecified
0.696 0.304 0.000
E14.6 With other specified complications
0.695 0.305 0.000
K74.4 Secondary biliary cirrhosis
0.694 0.305 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.694 0.305 0.000
K74.1 Hepatic sclerosis
0.694 0.305 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.694 0.305 0.000
E07.8 Other specified disorders of thyroid
0.694 0.306 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.694 0.306 0.000
M22.8 Other disorders of patella
0.694 0.306 0.000
E88.9 Metabolic disorder, unspecified
0.694 0.306 0.000
K90.9 Intestinal malabsorption, unspecified
0.694 0.306 0.000
E88.3 Tumour lysis syndrome
0.694 0.306 0.000
M24.6 Ankylosis of joint
0.693 0.307 0.000
M10 Gout
0.693 0.307 0.000
E27.5 Adrenomedullary hyperfunction
0.692 0.308 0.000
E27.0 Other adrenocortical overactivity
0.692 0.308 0.000
Chapter XIV Diseases of the genitourinary system
0.692 0.308 0.000
L43.9 Lichen planus, unspecified
0.691 0.309 0.000
L54 Erythema in diseases classified elsewhere
0.691 0.309 0.000
D62 Acute posthaemorrhagic anaemia
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.689 0.311 0.000
M34.0 Progressive systemic sclerosis
0.689 0.311 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.689 0.311 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.689 0.311 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.689 0.311 0.000
M34.1 CR(E)ST syndrome
0.688 0.312 0.000
C93 Monocytic leukaemia
0.688 0.312 0.000
E58 Dietary calcium deficiency
0.687 0.313 0.000
N05.6 Dense deposit disease
0.687 0.313 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.687 0.313 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.687 0.313 0.000
N05.0 Minor glomerular abnormality
0.687 0.313 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.686 0.313 0.000
D72.8 Other specified disorders of white blood cells
0.686 0.314 0.000
L93.0 Discoid lupus erythematosus
0.686 0.314 0.000
B37.2 Candidiasis of skin and nail
0.685 0.315 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.685 0.315 0.000
D69.4 Other primary thrombocytopenia
0.684 0.316 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.683 0.317 0.000
Q03 Congenital hydrocephalus
0.682 0.318 0.000
G62.2 Polyneuropathy due to other toxic agents
0.680 0.320 0.000
B37.4 Candidiasis of other urogenital sites
0.680 0.320 0.000
G00 Bacterial meningitis, not elsewhere classified
0.680 0.320 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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