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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs653414
log Bayes Factor = 25.8545
Chromosome 6   position 31,907,168  (GRCh37) Explore rs653414 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.009 0.991
E11 Non-insulin-dependent diabetes mellitus
0.000 0.024 0.976
E05.9 Thyrotoxicosis, unspecified
0.000 0.035 0.965
E10.1 With ketoacidosis
0.000 0.049 0.951
E11.3 With ophthalmic complications
0.000 0.054 0.946
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.061 0.939
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.063 0.937
E65-E68 Obesity and other hyperalimentation
0.000 0.073 0.927
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.118 0.882
E66 Obesity
0.000 0.129 0.871
E10.5 With peripheral circulatory complications
0.000 0.136 0.864
E66.8 Other obesity
0.000 0.137 0.863
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.138 0.862
E11.9 Without complications
0.000 0.142 0.858
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.152 0.848
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.162 0.838
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.193 0.807
E11.5 With peripheral circulatory complications
0.000 0.199 0.801
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.201 0.799
E06 Thyroiditis
0.000 0.212 0.788
M06 Other rheumatoid arthritis
0.000 0.221 0.778
E10.4 With neurological complications
0.000 0.225 0.774
E10.2 With renal complications
0.000 0.235 0.765
E11.2 With renal complications
0.000 0.246 0.754
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.265 0.735
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E11.7 With multiple complications
0.000 0.300 0.700
E13 Other specified diabetes mellitus
0.000 0.301 0.699
M06.0 Seronegative rheumatoid arthritis
0.000 0.303 0.697
E11.0 With coma
0.000 0.305 0.695
E50-E64 Other nutritional deficiencies
0.000 0.311 0.689
E65 Localised adiposity
0.000 0.315 0.685
E11.6 With other specified complications
0.000 0.329 0.671
E10.8 With unspecified complications
0.000 0.334 0.666
E67 Other hyperalimentation
0.000 0.335 0.664
E68 Sequelae of hyperalimentation
0.000 0.335 0.664
E14 Unspecified diabetes mellitus
0.000 0.349 0.651
E11.8 With unspecified complications
0.000 0.354 0.646
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.357 0.643
E06.3 Autoimmune thyroiditis
0.000 0.357 0.643
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.371 0.629
E66.1 Drug-induced obesity
0.000 0.375 0.624
E40-E46 Malnutrition
0.000 0.388 0.612
E11.1 With ketoacidosis
0.000 0.391 0.608
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.402 0.598
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.403 0.597
M06.3 Rheumatoid nodule
0.000 0.405 0.594
E66.0 Obesity due to excess calories
0.000 0.414 0.586
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.417 0.583
E11.4 With neurological complications
0.000 0.426 0.574
E06.5 Other chronic thyroiditis
0.000 0.435 0.565
E06.4 Drug-induced thyroiditis
0.000 0.435 0.565
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.435 0.565
E06.1 Subacute thyroiditis
0.000 0.435 0.565
E06.0 Acute thyroiditis
0.000 0.435 0.565
M06.8 Other specified rheumatoid arthritis
0.000 0.442 0.558
M06.2 Rheumatoid bursitis
0.000 0.442 0.558
M06.1 Adult-onset Still's disease
0.000 0.442 0.558
E06.9 Thyroiditis, unspecified
0.000 0.447 0.553
E03.8 Other specified hypothyroidism
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.4 Inflammatory polyarthropathy
0.000 0.487 0.513
E14.3 With ophthalmic complications
0.000 0.489 0.511
E13.8 With unspecified complications
0.000 0.498 0.501
E13.7 With multiple complications
0.000 0.498 0.501
E13.6 With other specified complications
0.000 0.498 0.501
E13.5 With peripheral circulatory complications
0.000 0.498 0.501
E13.4 With neurological complications
0.000 0.498 0.501
E13.3 With ophthalmic complications
0.000 0.498 0.501
E13.2 With renal complications
0.000 0.498 0.501
E13.1 With ketoacidosis
0.000 0.498 0.501
E13.0 With coma
0.000 0.498 0.501
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.500 0.500
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.500 0.500
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.500 0.500
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.500 0.500
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.500 0.500
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.500 0.500
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.500 0.500
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.500 0.500
E07 Other disorders of thyroid
0.000 0.504 0.496
E61 Deficiency of other nutrient elements
0.000 0.505 0.495
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.506 0.494
E63 Other nutritional deficiencies
0.000 0.506 0.494
E56 Other vitamin deficiencies
0.000 0.506 0.494
E51 Thiamine deficiency
0.000 0.506 0.494
E50 Vitamin A deficiency
0.000 0.506 0.494
E60 Dietary zinc deficiency
0.000 0.506 0.494
E59 Dietary selenium deficiency
0.000 0.506 0.494
E58 Dietary calcium deficiency
0.000 0.506 0.494
E54 Ascorbic acid deficiency
0.000 0.506 0.494
E52 Niacin deficiency [pellagra]
0.000 0.506 0.494
E55 Vitamin D deficiency
0.000 0.511 0.489
E13.9 Without complications
0.000 0.516 0.484
E67.8 Other specified hyperalimentation
0.000 0.523 0.476
E67.3 Hypervitaminosis D
0.000 0.523 0.476
E67.2 Megavitamin-B6 syndrome
0.000 0.523 0.476
E67.1 Hypercarotenaemia
0.000 0.523 0.476
E67.0 Hypervitaminosis A
0.000 0.523 0.476
E53 Deficiency of other B group vitamins
0.000 0.528 0.472
E14.8 With unspecified complications
0.000 0.533 0.467
E14.7 With multiple complications
0.000 0.533 0.467
E14.6 With other specified complications
0.000 0.533 0.467
E14.5 With peripheral circulatory complications
0.000 0.533 0.467
E14.4 With neurological complications
0.000 0.533 0.467
E14.1 With ketoacidosis
0.000 0.533 0.467
E14.0 With coma
0.000 0.533 0.467
M06.34 Rheumatoid nodule (Hand)
0.000 0.537 0.463
E15 Nondiabetic hypoglycaemic coma
0.000 0.539 0.461
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.561 0.439
E45 Retarded development following protein-energy malnutrition
0.000 0.561 0.439
E43 Unspecified severe protein-energy malnutrition
0.000 0.561 0.439
E42 Marasmic kwashiorkor
0.000 0.561 0.439
E41 Nutritional marasmus
0.000 0.561 0.439
E40 Kwashiorkor
0.000 0.561 0.439
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.573 0.426
M06.38 Rheumatoid nodule (Other)
0.000 0.573 0.426
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.573 0.426
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.573 0.426
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.573 0.426
M06.33 Rheumatoid nodule (Forearm)
0.000 0.573 0.426
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.573 0.426
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.573 0.426
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.573 0.426
E20-E35 Disorders of other endocrine glands
0.000 0.574 0.426
E04 Other non-toxic goitre
0.000 0.578 0.422
E14.9 Without complications
0.000 0.578 0.422
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.599 0.400
M06.18 Adult-onset Still's disease (Other)
0.000 0.599 0.400
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.599 0.400
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.599 0.400
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.599 0.400
M06.14 Adult-onset Still's disease (Hand)
0.000 0.599 0.400
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.599 0.400
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.599 0.400
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.599 0.400
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.599 0.400
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.599 0.400
M06.28 Rheumatoid bursitis (Other)
0.000 0.599 0.400
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.599 0.400
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.599 0.400
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.599 0.400
M06.24 Rheumatoid bursitis (Hand)
0.000 0.599 0.400
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.599 0.400
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.599 0.400
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.599 0.400
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.599 0.400
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.599 0.400
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.599 0.400
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.599 0.400
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.599 0.400
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.599 0.400
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.599 0.400
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.599 0.400
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.599 0.400
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.599 0.400
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.599 0.400
E27 Other disorders of adrenal gland
0.000 0.611 0.389
E16 Other disorders of pancreatic internal secretion
0.000 0.611 0.388
E14.2 Withrenal complications
0.000 0.614 0.386
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.632 0.368
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.632 0.368
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.632 0.368
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.632 0.368
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.632 0.368
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.632 0.368
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.632 0.368
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.632 0.368
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.632 0.368
E61.1 Iron deficiency
0.000 0.644 0.356
E07.1 Dyshormogenetic goitre
0.000 0.644 0.355
E07.0 Hypersecretion of calcitonin
0.000 0.644 0.355
E61.9 Deficiency of nutrient element, unspecified
0.000 0.645 0.355
E61.8 Deficiency of other specified nutrient elements
0.000 0.645 0.355
E61.7 Deficiency of multiple nutrient elements
0.000 0.645 0.355
E61.6 Vanadium deficiency
0.000 0.645 0.355
E61.5 Molybdenum deficiency
0.000 0.645 0.355
E61.4 Chromium deficiency
0.000 0.645 0.355
E61.3 Manganese deficiency
0.000 0.645 0.355
E61.2 Magnesium deficiency
0.000 0.645 0.355
E61.0 Copper deficiency
0.000 0.645 0.355
E50.9 Vitamin A deficiency, unspecified
0.000 0.645 0.354
E50.8 Other manifestations of vitamin A deficiency
0.000 0.645 0.354
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.645 0.354
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.645 0.354
E50.5 Vitamin A deficiency with night blindness
0.000 0.645 0.354
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.645 0.354
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.645 0.354
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.645 0.354
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.645 0.354
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.645 0.354
E51.9 Thiamine deficiency, unspecified
0.000 0.645 0.354
E51.8 Other manifestations of thiamine deficiency
0.000 0.645 0.354
E51.2 Wernicke's encephalopathy
0.000 0.645 0.354
E51.1 Beriberi
0.000 0.645 0.354
E56.9 Vitamin deficiency, unspecified
0.000 0.645 0.354
E56.8 Deficiency of other vitamins
0.000 0.645 0.354
E56.1 Deficiency of vitamin K
0.000 0.645 0.354
E56.0 Deficiency of vitamin E
0.000 0.645 0.354
E63.9 Nutritional deficiency, unspecified
0.000 0.645 0.354
E63.8 Other specified nutritional deficiencies
0.000 0.645 0.354
E63.1 Imbalance of constituents of food intake
0.000 0.645 0.354
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.645 0.354
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.645 0.354
E64.8 Sequelae of other nutritional deficiencies
0.000 0.645 0.354
E64.3 Sequelae of rickets
0.000 0.645 0.354
E64.2 Sequelae of vitamin C deficiency
0.000 0.645 0.354
E64.1 Sequelae of vitamin A deficiency
0.000 0.645 0.354
E64.0 Sequelae of protein-energy malnutrition
0.000 0.645 0.354
M05-M14 Inflammatory polyarthropathies
0.004 0.648 0.349
E55.0 Rickets, active
0.000 0.649 0.351
E55.9 Vitamin D deficiency, unspecified
0.000 0.654 0.346
E27.1 Primary adrenocortical insufficiency
0.000 0.658 0.342
E53.1 Pyridoxine deficiency
0.000 0.662 0.338
E53.0 Riboflavin deficiency
0.000 0.662 0.338
E07.8 Other specified disorders of thyroid
0.000 0.662 0.337
E53.8 Deficiency of other specified B group vitamins
0.000 0.664 0.336
E46 Unspecified protein-energy malnutrition
0.000 0.665 0.334
E20 Hypoparathyroidism
0.000 0.666 0.334
E04.0 Non-toxic diffuse goitre
0.000 0.667 0.333
E27.8 Other specified disorders of adrenal gland
0.000 0.673 0.327
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.677 0.323
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.677 0.322
E04.2 Non-toxic multinodular goitre
0.000 0.681 0.319
S61.0 Open wound of finger(s) without damage to nail
0.318 0.682 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.682 0.318
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.684 0.316
E44.1 Mild protein-energy malnutrition
0.000 0.685 0.315
E44.0 Moderate protein-energy malnutrition
0.000 0.685 0.315
M05 Seropositive rheumatoid arthritis
0.002 0.692 0.306
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.694 0.305
E32 Diseases of thymus
0.000 0.694 0.305
E31 Polyglandular dysfunction
0.000 0.694 0.305
E30 Disorders of puberty, not elsewhere classified
0.000 0.694 0.305
E04.8 Other specified non-toxic goitre
0.000 0.697 0.303
E22 Hyperfunction of pituitary gland
0.000 0.705 0.295
M07 Psoriatic and enteropathic arthropathies
0.002 0.705 0.292
E27.2 Addisonian crisis
0.000 0.706 0.294
L40.9 Psoriasis, unspecified
0.000 0.713 0.287
L40 Psoriasis
0.000 0.714 0.286
L40.5 Arthropathic psoriasis
0.000 0.714 0.286
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.719 0.281
E27.5 Adrenomedullary hyperfunction
0.000 0.721 0.279
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.721 0.279
E27.0 Other adrenocortical overactivity
0.000 0.721 0.279
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.721 0.279
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.721 0.279
E16.4 Abnormal secretion of gastrin
0.000 0.721 0.279
E16.3 Increased secretion of glucagon
0.000 0.721 0.279
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.723 0.276
E28 Ovarian dysfunction
0.000 0.726 0.274
E20.9 Hypoparathyroidism, unspecified
0.000 0.732 0.268
E26 Hyperaldosteronism
0.000 0.735 0.265
E21.3 Hyperparathyroidism, unspecified
0.000 0.738 0.262
S61 Open wound of wrist and hand
0.260 0.740 0.000
E16.1 Other hypoglycaemia
0.000 0.743 0.257
E24 Cushing's syndrome
0.000 0.745 0.255
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.746 0.254
M07.3 Other psoriatic arthropathies
0.001 0.747 0.252
M12 Other specific arthropathies
0.003 0.747 0.250
M09 Juvenile arthritis in diseases classified elsewhere
0.003 0.747 0.250
M08 Juvenile arthritis
0.003 0.747 0.250
E25 Adrenogenital disorders
0.001 0.750 0.250
M14 Arthropathies in other diseases classified elsewhere
0.003 0.753 0.244
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.755 0.245
S61.1 Open wound of finger(s) with damage to nail
0.244 0.756 0.000
E29 Testicular dysfunction
0.000 0.759 0.241
L40.0 Psoriasis vulgaris
0.000 0.760 0.240
E20.8 Other hypoparathyroidism
0.000 0.761 0.239
E20.1 Pseudohypoparathyroidism
0.000 0.761 0.239
E20.0 Idiopathic hypoparathyroidism
0.000 0.761 0.239
E22.1 Hyperprolactinaemia
0.000 0.762 0.238
E23 Hypofunction and other disorders of pituitary gland
0.000 0.765 0.235
E16.2 Hypoglycaemia, unspecified
0.000 0.768 0.232
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.768 0.232
E21.4 Other specified disorders of parathyroid gland
0.000 0.768 0.232
E21.2 Other hyperparathyroidism
0.000 0.768 0.232
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.770 0.229
M11 Other crystal arthropathies
0.003 0.771 0.226
M05.8 Other seropositive rheumatoid arthritis
0.002 0.779 0.220
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.779 0.220
M05.2 Rheumatoid vasculitis
0.002 0.779 0.220
M05.1 Rheumatoid lung disease
0.002 0.779 0.220
M05.0 Felty's syndrome
0.002 0.779 0.220
E30.9 Disorder of puberty, unspecified
0.000 0.781 0.219
E30.8 Other disorders of puberty
0.000 0.781 0.219
E30.1 Precocious puberty
0.000 0.781 0.219
E30.0 Delayed puberty
0.000 0.781 0.219
E31.9 Polyglandular dysfunction, unspecified
0.000 0.781 0.219
E31.8 Other polyglandular dysfunction
0.000 0.781 0.219
E31.1 Polyglandular hyperfunction
0.000 0.781 0.219
E31.0 Autoimmune polyglandular failure
0.000 0.781 0.219
E32.9 Disease of thymus, unspecified
0.000 0.781 0.219
E32.8 Other diseases of thymus
0.000 0.781 0.219
E32.1 Abscess of thymus
0.000 0.781 0.219
E32.0 Persistent hyperplasia of thymus
0.000 0.781 0.219
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.781 0.219
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.781 0.219
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.781 0.219
S61.9 Open wound of wrist and hand, part unspecified
0.215 0.785 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.788 0.212
E22.8 Other hyperfunction of pituitary gland
0.000 0.788 0.212
M07.6 Other enteropathic arthropathies
0.002 0.789 0.210
M07.5 Arthropathy in ulcerative colitis
0.002 0.789 0.210
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.002 0.789 0.210
M07.2 Psoriatic spondylitis
0.002 0.789 0.210
M07.1 Arthritis mutilans
0.002 0.789 0.210
M07.0 Distal interphalangeal psoriatic arthropathy
0.002 0.789 0.210
L40.8 Other psoriasis
0.000 0.789 0.211
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.790 0.210
L40.4 Guttate psoriasis
0.000 0.794 0.205
L40.3 Pustulosis palmaris et plantaris
0.000 0.794 0.205
L40.2 Acrodermatitis continua
0.000 0.794 0.205
L40.1 Generalised pustular psoriasis
0.000 0.794 0.205
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.795 0.204
E34 Other endocrine disorders
0.001 0.796 0.203
M10 Gout
0.002 0.797 0.201
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.801 0.198
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.801 0.198
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.801 0.198
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.801 0.198
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.801 0.198
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.801 0.198
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.801 0.198
E27.9 Disorder of adrenal gland, unspecified
0.000 0.803 0.197
E28.9 Ovarian dysfunction, unspecified
0.000 0.803 0.197
E28.8 Other ovarian dysfunction
0.000 0.803 0.197
E28.3 Primary ovarian failure
0.000 0.803 0.197
E28.1 Androgen excess
0.000 0.803 0.197
E28.0 Oestrogen excess
0.000 0.803 0.197
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.808 0.191
E26.9 Hyperaldosteronism, unspecified
0.000 0.810 0.190
E26.8 Other hyperaldosteronism
0.000 0.810 0.190
E26.1 Secondary hyperaldosteronism
0.000 0.810 0.190
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.813 0.186
E22.0 Acromegaly and pituitary gigantism
0.000 0.814 0.185
E24.8 Other Cushing's syndrome
0.000 0.817 0.183
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.817 0.183
E24.3 Ectopic ACTH syndrome
0.000 0.817 0.183
E24.2 Drug-induced Cushing's syndrome
0.000 0.817 0.183
E24.1 Nelson's syndrome
0.000 0.817 0.183
E24.0 Pituitary-dependent Cushing's disease
0.000 0.817 0.183
M07.38 Other psoriatic arthropathies (Other)
0.001 0.818 0.181
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.001 0.818 0.181
M07.36 Other psoriatic arthropathies (Lower leg)
0.001 0.818 0.181
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.001 0.818 0.181
M07.34 Other psoriatic arthropathies (Hand)
0.001 0.818 0.181
M07.33 Other psoriatic arthropathies (Forearm)
0.001 0.818 0.181
M07.32 Other psoriatic arthropathies (Upper arm)
0.001 0.818 0.181
M07.31 Other psoriatic arthropathies (Shoulder region)
0.001 0.818 0.181
M08.9 Juvenile arthritis, unspecified
0.002 0.818 0.179
M08.8 Other juvenile arthritis
0.002 0.818 0.179
M08.4 Pauciarticular juvenile arthritis
0.002 0.818 0.179
M08.3 Juvenile polyarthritis (seronegative)
0.002 0.818 0.179
M08.2 Juvenile arthritis with systemic onset
0.002 0.818 0.179
M08.1 Juvenile ankylosing spondylitis
0.002 0.818 0.179
M08.0 Juvenile rheumatoid arthritis
0.002 0.818 0.179
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.002 0.818 0.179
M09.2 Juvenile arthritis in ulcerative colitis
0.002 0.818 0.179
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.002 0.818 0.179
M09.0 Juvenile arthritis in psoriasis
0.002 0.818 0.179
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.818 0.179
M12.5 Traumatic arthropathy
0.002 0.818 0.179
M12.4 Intermittent hydrarthrosis
0.002 0.818 0.179
M12.3 Palindromic rheumatism
0.002 0.818 0.179
M12.2 Villonodular synovitis (pigmented)
0.002 0.818 0.179
M12.1 Kaschin-Beck disease
0.002 0.818 0.179
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.818 0.179
E25.9 Adrenogenital disorder, unspecified
0.001 0.820 0.179
E25.8 Other adrenogenital disorders
0.001 0.820 0.179
E21.0 Primary hyperparathyroidism
0.000 0.822 0.178
M14.8 Arthropathies in other specified diseases classified elsewhere
0.002 0.823 0.175
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.002 0.823 0.175
M14.4 Arthropathy in amyloidosis
0.002 0.823 0.175
M14.3 Lipoid dermatoarthritis
0.002 0.823 0.175
M14.2 Diabetic arthropathy
0.002 0.823 0.175
M14.1 Crystal arthropathy in other metabolic disorders
0.002 0.823 0.175
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.002 0.823 0.175
E07.9 Disorder of thyroid, unspecified
0.001 0.823 0.176
S61.7 Multiple open wounds of wrist and hand
0.176 0.824 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.827 0.173
E29.8 Other testicular dysfunction
0.000 0.827 0.173
E29.0 Testicular hyperfunction
0.000 0.827 0.173
L40-L45 Papulosquamous disorders
0.000 0.828 0.172
M14.6 Neuropathic arthropathy
0.002 0.829 0.169
E23.7 Disorder of pituitary gland, unspecified
0.000 0.831 0.169
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.831 0.168
E23.1 Drug-induced hypopituitarism
0.000 0.831 0.168
E28.2 Polycystic ovarian syndrome
0.000 0.834 0.165
M11.9 Crystal arthropathy, unspecified
0.002 0.836 0.162
M11.8 Other specified crystal arthropathies
0.002 0.836 0.162
M11.1 Familial chondrocalcinosis
0.002 0.836 0.162
M11.0 Hydroxyapatite deposition disease
0.002 0.836 0.162
E23.2 Diabetes insipidus
0.000 0.837 0.162
E04.1 Non-toxic single thyroid nodule
0.000 0.841 0.159
M05.09 Felty's syndrome (Site unspecified)
0.001 0.841 0.158
M05.08 Felty's syndrome (Other)
0.001 0.841 0.158
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.841 0.158
M05.06 Felty's syndrome (Lower leg)
0.001 0.841 0.158
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.841 0.158
M05.04 Felty's syndrome (Hand)
0.001 0.841 0.158
M05.03 Felty's syndrome (Forearm)
0.001 0.841 0.158
M05.02 Felty's syndrome (Upper arm)
0.001 0.841 0.158
M05.01 Felty's syndrome (Shoulder region)
0.001 0.841 0.158
M05.00 Felty's syndrome (Multiple sites)
0.001 0.841 0.158
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.841 0.158
M05.18 Rheumatoid lung disease (Other)
0.001 0.841 0.158
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.841 0.158
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.841 0.158
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.841 0.158
M05.14 Rheumatoid lung disease (Hand)
0.001 0.841 0.158
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.841 0.158
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.841 0.158
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.841 0.158
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.841 0.158
M05.29 Rheumatoid vasculitis (Site unspecified)
0.001 0.841 0.158
M05.28 Rheumatoid vasculitis (Other)
0.001 0.841 0.158
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.001 0.841 0.158
M05.26 Rheumatoid vasculitis (Lower leg)
0.001 0.841 0.158
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.001 0.841 0.158
M05.24 Rheumatoid vasculitis (Hand)
0.001 0.841 0.158
M05.23 Rheumatoid vasculitis (Forearm)
0.001 0.841 0.158
M05.22 Rheumatoid vasculitis (Upper arm)
0.001 0.841 0.158
M05.21 Rheumatoid vasculitis (Shoulder region)
0.001 0.841 0.158
M05.20 Rheumatoid vasculitis (Multiple sites)
0.001 0.841 0.158
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.841 0.158
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.841 0.158
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.841 0.158
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.841 0.158
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.841 0.158
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.841 0.158
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.841 0.158
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.841 0.158
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.841 0.158
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.841 0.158
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.001 0.841 0.158
M05.88 Other seropositive rheumatoid arthritis (Other)
0.001 0.841 0.158
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.001 0.841 0.158
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.001 0.841 0.158
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.001 0.841 0.158
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.001 0.841 0.158
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.001 0.841 0.158
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.001 0.841 0.158
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.001 0.841 0.158
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.001 0.841 0.158
M13 Other arthritis
0.002 0.841 0.157
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.848 0.151
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.848 0.151
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.848 0.151
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.848 0.151
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.848 0.151
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.848 0.151
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.848 0.151
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.848 0.151
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.848 0.151

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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