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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs654537
log Bayes Factor = 16.285
Chromosome 6   position 90,990,050  (GRCh37) Explore rs654537 on Ensembl!
Variant rs654537 is part of Cluster X0108

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
C44.6 Skin of upper limb, including shoulder
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.997 0.003 0.000
C44.5 Skin of trunk
0.982 0.018 0.000
C44.7 Skin of lower limb, including hip
0.978 0.022 0.000
C44.2 Skin of ear and external auricular canal
0.922 0.078 0.000
C44.0 Skin of lip
0.850 0.150 0.000
C44.8 Overlapping lesion of skin
0.715 0.285 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.703 0.297 0.000
C44.4 Skin of scalp and neck
0.673 0.327 0.000
C44.1 Skin of eyelid, including canthus
0.598 0.402 0.000
E03 Other hypothyroidism
0.000 0.557 0.442
C43-C44 Melanoma and other malignant neoplasms of skin
0.406 0.594 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.651 0.349
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.681 0.319
E03.5 Myxoedema coma
0.000 0.682 0.317
E03.4 Atrophy of thyroid (acquired)
0.000 0.682 0.317
E03.3 Postinfectious hypothyroidism
0.000 0.682 0.317
C43 Malignant melanoma of skin
0.286 0.714 0.000
E00-E07 Disorders of thyroid gland
0.000 0.726 0.274
C43.6 Malignant melanoma of upper limb, including shoulder
0.270 0.730 0.000
E06 Thyroiditis
0.000 0.735 0.265
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.735 0.265
E06.3 Autoimmune thyroiditis
0.000 0.740 0.260
C43.9 Malignant melanoma of skin, unspecified
0.251 0.749 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.225 0.775 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.778 0.222
C43.8 Overlapping malignant melanoma of skin
0.205 0.795 0.000
C43.0 Malignant melanoma of lip
0.205 0.795 0.000
E06.5 Other chronic thyroiditis
0.000 0.798 0.202
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.803 0.197
E00 Congenital iodine-deficiency syndrome
0.000 0.803 0.197
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.805 0.195
C43.1 Malignant melanoma of eyelid, including canthus
0.194 0.805 0.000
E06.1 Subacute thyroiditis
0.000 0.807 0.193
E06.4 Drug-induced thyroiditis
0.000 0.810 0.190
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.810 0.190
E06.0 Acute thyroiditis
0.000 0.810 0.190
C44.3 Skin of other and unspecified parts of face
0.184 0.816 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.166 0.833 0.000
E06.9 Thyroiditis, unspecified
0.000 0.836 0.164
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.837 0.163
E03.8 Other specified hypothyroidism
0.001 0.842 0.157
E05.9 Thyrotoxicosis, unspecified
0.000 0.850 0.150
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.859 0.141
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.859 0.141
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.859 0.141
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.859 0.141
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.859 0.141
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.859 0.141
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.859 0.141
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.859 0.141
E05.5 Thyroid crisis or storm
0.000 0.860 0.140
E05.4 Thyrotoxicosis factitia
0.000 0.860 0.140
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.860 0.140
C43.4 Malignant melanoma of scalp and neck
0.135 0.864 0.000
E07 Other disorders of thyroid
0.000 0.866 0.134
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.866 0.134
E05.8 Other thyrotoxicosis
0.000 0.871 0.129
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.892 0.108
C43.5 Malignant melanoma of trunk
0.108 0.892 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.097 0.903 0.000
E07.1 Dyshormogenetic goitre
0.000 0.903 0.096
E07.0 Hypersecretion of calcitonin
0.000 0.903 0.096
J45.9 Asthma, unspecified
0.089 0.911 0.000
E07.8 Other specified disorders of thyroid
0.000 0.917 0.083
E07.9 Disorder of thyroid, unspecified
0.000 0.940 0.060
E10.9 Without complications
0.000 0.954 0.046
E10 Insulin-dependent diabetes mellitus
0.000 0.954 0.046
E10-E14 Diabetes mellitus
0.000 0.957 0.043
E10.4 With neurological complications
0.000 0.958 0.042
E10.3 With ophthalmic complications
0.000 0.958 0.042
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.958 0.042
E11 Non-insulin-dependent diabetes mellitus
0.000 0.962 0.038
E11.4 With neurological complications
0.000 0.963 0.037
E10.1 With ketoacidosis
0.000 0.963 0.037
E11.2 With renal complications
0.000 0.965 0.035
Z03.5 Observation for other suspected cardiovascular diseases
0.000 0.965 0.035
E10.6 With other specified complications
0.000 0.966 0.034
E10.7 With multiple complications
0.000 0.968 0.032
E10.0 With coma
0.000 0.969 0.031
E12 Malnutrition-related diabetes mellitus
0.000 0.969 0.031
E11.6 With other specified complications
0.000 0.969 0.031
E11.0 With coma
0.000 0.970 0.030
E10.8 With unspecified complications
0.000 0.970 0.030
E40-E46 Malnutrition
0.000 0.972 0.028
E11.7 With multiple complications
0.000 0.973 0.027
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.973 0.027
E13 Other specified diabetes mellitus
0.000 0.974 0.026
E11.5 With peripheral circulatory complications
0.000 0.975 0.025
E11.1 With ketoacidosis
0.000 0.975 0.025
E10.5 With peripheral circulatory complications
0.000 0.975 0.025
E10.2 With renal complications
0.000 0.975 0.025
J45 Asthma
0.025 0.975 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.977 0.023
E12.9 Without complications
0.000 0.977 0.022
E12.8 With unspecified complications
0.000 0.977 0.022
E12.7 With multiple complications
0.000 0.977 0.022
E12.6 With other specified complications
0.000 0.977 0.022
E12.5 With peripheral circulatory complications
0.000 0.977 0.022
E12.4 With neurological complications
0.000 0.977 0.022
E12.3 With ophthalmic complications
0.000 0.977 0.022
E12.2 With renal complications
0.000 0.977 0.022
E12.1 With ketoacidosis
0.000 0.977 0.022
E12.0 With coma
0.000 0.977 0.022
T78.2 Anaphylactic shock, unspecified
0.022 0.978 0.000
E11.8 With unspecified complications
0.000 0.979 0.021
E14 Unspecified diabetes mellitus
0.000 0.979 0.021
E04 Other non-toxic goitre
0.000 0.979 0.021
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.980 0.020
E45 Retarded development following protein-energy malnutrition
0.000 0.980 0.020
E43 Unspecified severe protein-energy malnutrition
0.000 0.980 0.020
E42 Marasmic kwashiorkor
0.000 0.980 0.020
E41 Nutritional marasmus
0.000 0.980 0.020
E40 Kwashiorkor
0.000 0.980 0.020
J45.1 Nonallergic asthma
0.020 0.980 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.980 0.020
E65 Localised adiposity
0.000 0.981 0.019
E13.8 With unspecified complications
0.000 0.981 0.019
E13.7 With multiple complications
0.000 0.981 0.019
E13.6 With other specified complications
0.000 0.981 0.019
E13.5 With peripheral circulatory complications
0.000 0.981 0.019
E13.4 With neurological complications
0.000 0.981 0.019
E13.3 With ophthalmic complications
0.000 0.981 0.019
E13.2 With renal complications
0.000 0.981 0.019
E13.1 With ketoacidosis
0.000 0.981 0.019
E13.0 With coma
0.000 0.981 0.019
E50-E64 Other nutritional deficiencies
0.000 0.981 0.019
E46 Unspecified protein-energy malnutrition
0.000 0.982 0.018
E11.3 With ophthalmic complications
0.000 0.982 0.018
J45.8 Mixed asthma
0.017 0.982 0.000
E14.8 With unspecified complications
0.000 0.983 0.017
C67 Malignant neoplasm of bladder
0.000 0.983 0.017
E16 Other disorders of pancreatic internal secretion
0.000 0.983 0.017
E67 Other hyperalimentation
0.000 0.983 0.017
E68 Sequelae of hyperalimentation
0.000 0.983 0.017
C67.3 Anterior wall of bladder
0.000 0.983 0.017
E14.2 Withrenal complications
0.000 0.983 0.016
C67.6 Ureteric orifice
0.000 0.984 0.016
E14.4 With neurological complications
0.000 0.984 0.016
S42.20 Fracture of upper end of humerus (closed)
0.016 0.984 0.000
E14.6 With other specified complications
0.000 0.984 0.016
C67.9 Bladder, unspecified
0.000 0.984 0.016
E14.1 With ketoacidosis
0.000 0.984 0.016
E14.7 With multiple complications
0.000 0.985 0.015
E14.0 With coma
0.000 0.985 0.015
E04.8 Other specified non-toxic goitre
0.000 0.985 0.015
E44.1 Mild protein-energy malnutrition
0.000 0.985 0.015
E44.0 Moderate protein-energy malnutrition
0.000 0.985 0.015
C67.4 Posterior wall of bladder
0.000 0.986 0.014
E51 Thiamine deficiency
0.000 0.986 0.014
E58 Dietary calcium deficiency
0.000 0.986 0.014
E13.9 Without complications
0.000 0.986 0.014
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.986 0.014
E63 Other nutritional deficiencies
0.000 0.986 0.014
E50 Vitamin A deficiency
0.000 0.986 0.014
E60 Dietary zinc deficiency
0.000 0.986 0.014
E59 Dietary selenium deficiency
0.000 0.986 0.014
E54 Ascorbic acid deficiency
0.000 0.986 0.014
E52 Niacin deficiency [pellagra]
0.000 0.986 0.014
E56 Other vitamin deficiencies
0.000 0.986 0.013
C67.1 Dome of bladder
0.000 0.987 0.013
C67.0 Trigone of bladder
0.000 0.987 0.013
E04.0 Non-toxic diffuse goitre
0.000 0.987 0.013
C67.5 Bladder neck
0.000 0.987 0.013
E14.5 With peripheral circulatory complications
0.000 0.987 0.013
E14.3 With ophthalmic complications
0.000 0.987 0.013
C67.7 Urachus
0.000 0.988 0.012
E16.1 Other hypoglycaemia
0.000 0.988 0.012
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.988 0.012
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.988 0.012
E16.4 Abnormal secretion of gastrin
0.000 0.988 0.012
E16.3 Increased secretion of glucagon
0.000 0.988 0.012
E67.8 Other specified hyperalimentation
0.000 0.988 0.012
E67.3 Hypervitaminosis D
0.000 0.988 0.012
E67.2 Megavitamin-B6 syndrome
0.000 0.988 0.012
E67.1 Hypercarotenaemia
0.000 0.988 0.012
E67.0 Hypervitaminosis A
0.000 0.988 0.012
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.988 0.012
E61 Deficiency of other nutrient elements
0.000 0.988 0.012
C67.8 Overlapping lesion of bladder
0.000 0.988 0.012
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.011 0.989 0.000
E53 Deficiency of other B group vitamins
0.000 0.989 0.011
E51.2 Wernicke's encephalopathy
0.000 0.989 0.010
C67.2 Lateral wall of bladder
0.000 0.989 0.011
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.000 0.990 0.010
E51.9 Thiamine deficiency, unspecified
0.000 0.990 0.010
E51.8 Other manifestations of thiamine deficiency
0.000 0.990 0.010
E51.1 Beriberi
0.000 0.990 0.010
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.000 0.990 0.010
E50.9 Vitamin A deficiency, unspecified
0.000 0.990 0.010
E50.8 Other manifestations of vitamin A deficiency
0.000 0.990 0.010
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.990 0.010
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.990 0.010
E50.5 Vitamin A deficiency with night blindness
0.000 0.990 0.010
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.990 0.010
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.990 0.010
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.990 0.010
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.990 0.010
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.990 0.010
E63.9 Nutritional deficiency, unspecified
0.000 0.990 0.010
E63.8 Other specified nutritional deficiencies
0.000 0.990 0.010
E63.1 Imbalance of constituents of food intake
0.000 0.990 0.010
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.990 0.010
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.990 0.010
E64.8 Sequelae of other nutritional deficiencies
0.000 0.990 0.010
E64.3 Sequelae of rickets
0.000 0.990 0.010
E64.2 Sequelae of vitamin C deficiency
0.000 0.990 0.010
E64.1 Sequelae of vitamin A deficiency
0.000 0.990 0.010
E64.0 Sequelae of protein-energy malnutrition
0.000 0.990 0.010
E56.9 Vitamin deficiency, unspecified
0.000 0.990 0.010
E56.8 Deficiency of other vitamins
0.000 0.990 0.010
E56.0 Deficiency of vitamin E
0.000 0.990 0.010
E55 Vitamin D deficiency
0.000 0.990 0.010
M54.36 Sciatica (Lumbar region)
0.000 0.990 0.010
T83.0 Mechanical complication of urinary (indwelling) catheter
0.010 0.990 0.000
E56.1 Deficiency of vitamin K
0.000 0.990 0.010
E16.2 Hypoglycaemia, unspecified
0.000 0.991 0.009
E53.9 Vitamin B deficiency, unspecified
0.000 0.991 0.009
E61.9 Deficiency of nutrient element, unspecified
0.000 0.991 0.009
E61.8 Deficiency of other specified nutrient elements
0.000 0.991 0.009
E61.7 Deficiency of multiple nutrient elements
0.000 0.991 0.009
E61.6 Vanadium deficiency
0.000 0.991 0.009
E61.5 Molybdenum deficiency
0.000 0.991 0.009
E61.4 Chromium deficiency
0.000 0.991 0.009
E61.3 Manganese deficiency
0.000 0.991 0.009
E61.0 Copper deficiency
0.000 0.991 0.009
E61.2 Magnesium deficiency
0.000 0.991 0.009
E53.1 Pyridoxine deficiency
0.000 0.992 0.008
E53.0 Riboflavin deficiency
0.000 0.992 0.008
S42.2 Fracture of upper end of humerus
0.008 0.992 0.000
E55.0 Rickets, active
0.000 0.993 0.007
T78 Adverse effects, not elsewhere classified
0.007 0.993 0.000
Z92.3 Personal history of irradiation
0.007 0.993 0.000
E61.1 Iron deficiency
0.000 0.993 0.007
J45.0 Predominantly allergic asthma
0.007 0.993 0.000
C64-C68 Malignant neoplasms of urinary tract
0.000 0.994 0.006
E04.9 Non-toxic goitre, unspecified
0.000 0.994 0.006
T78.0 Anaphylactic shock due to adverse food reaction
0.006 0.994 0.000
S42.21 Fracture of upper end of humerus (open)
0.006 0.994 0.000
O48 Prolonged pregnancy
0.006 0.994 0.000
M54.3 Sciatica
0.000 0.994 0.006
T78.1 Other adverse food reactions, not elsewhere classified
0.005 0.994 0.000
M54.37 Sciatica (Lumbosacral region)
0.000 0.994 0.006
T78.9 Adverse effect, unspecified
0.005 0.994 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.995 0.005
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.000 0.995 0.005
W08.0 Home
0.005 0.995 0.000
T78.3 Angioneurotic oedema
0.005 0.995 0.000
K66.8 Other specified disorders of peritoneum
0.005 0.995 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.995 0.005
C65 Malignant neoplasm of renal pelvis
0.000 0.995 0.005
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.995 0.005
M54.35 Sciatica (Thoracolumbar region)
0.000 0.996 0.004
M54.34 Sciatica-Thoracic
0.000 0.996 0.004
M54.33 Sciatica-Cervicothoracic
0.000 0.996 0.004
M54.32 Sciatica-Cervical
0.000 0.996 0.004
M54.31 Sciatica-Occipit-atl-axl
0.000 0.996 0.004
T78.4 Allergy, unspecified
0.004 0.996 0.000
F10.0 Acute intoxication
0.004 0.996 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.996 0.004
T78.8 Other adverse effects, not elsewhere classified
0.004 0.996 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.996 0.004
L98.0 Pyogenic granuloma
0.004 0.996 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.004 0.996 0.000
E27 Other disorders of adrenal gland
0.000 0.996 0.004
C68.9 Urinary organ, unspecified
0.000 0.996 0.004
S62.20 Fracture of first metacarpal bone (closed)
0.004 0.996 0.000
E27.2 Addisonian crisis
0.000 0.996 0.004
C68.8 Overlapping lesion of urinary organs
0.000 0.996 0.003
C68.1 Paraurethral glands
0.000 0.996 0.003
E55.9 Vitamin D deficiency, unspecified
0.000 0.996 0.004
S66.8 Injury of other muscles and tendons at wrist and hand level
0.004 0.996 0.000
M54.30 Sciatica (Multiple sites in spine)
0.000 0.996 0.003
Z53.9 Procedure not carried out, unspecified reason
0.004 0.996 0.000
C66 Malignant neoplasm of ureter
0.000 0.996 0.003
M54.46 Lumbago with sciatica (Lumbar region)
0.000 0.997 0.003
O23.4 Unspecified infection of urinary tract in pregnancy
0.003 0.997 0.000
E26 Hyperaldosteronism
0.000 0.997 0.003
C68.0 Urethra
0.000 0.997 0.003
D86.0 Sarcoidosis of lung
0.000 0.997 0.003
H18.4 Corneal degeneration
0.000 0.997 0.003
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.997 0.003
E32 Diseases of thymus
0.000 0.997 0.003
E31 Polyglandular dysfunction
0.000 0.997 0.003
E30 Disorders of puberty, not elsewhere classified
0.000 0.997 0.003
E25 Adrenogenital disorders
0.000 0.997 0.003
M85.0 Fibrous dysplasia (monostotic)
0.003 0.997 0.000
E22 Hyperfunction of pituitary gland
0.000 0.997 0.003
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.003 0.997 0.000
O23.5 Infections of the genital tract in pregnancy
0.003 0.997 0.000
E34 Other endocrine disorders
0.000 0.997 0.003
K05.6 Periodontal disease, unspecified
0.000 0.997 0.003
O23 Infections of genito-urinary tract in pregnancy
0.003 0.997 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.003 0.997 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.997 0.003
E27.0 Other adrenocortical overactivity
0.000 0.997 0.003
C21.0 Anus, unspecified
0.000 0.997 0.003
E20 Hypoparathyroidism
0.000 0.997 0.003
E26.9 Hyperaldosteronism, unspecified
0.000 0.997 0.003
D59.1 Other autoimmune haemolytic anaemias
0.003 0.997 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.997 0.003
O23.0 Infections of kidney in pregnancy
0.003 0.997 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.003 0.997 0.000
H18.1 Bullous keratopathy
0.000 0.997 0.003
L53.9 Erythematous condition, unspecified
0.000 0.997 0.003
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.000 0.997 0.003
E34.9 Endocrine disorder, unspecified
0.000 0.997 0.003
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.997 0.003
M85.8 Other specified disorders of bone density and structure
0.003 0.997 0.000
M85 Other disorders of bone density and structure
0.003 0.997 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.000 0.997 0.003
D09.0 Bladder
0.000 0.997 0.003
E26.8 Other hyperaldosteronism
0.000 0.997 0.002
E26.1 Secondary hyperaldosteronism
0.000 0.997 0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.997 0.003
E30.9 Disorder of puberty, unspecified
0.000 0.997 0.002
E30.8 Other disorders of puberty
0.000 0.997 0.002
E30.1 Precocious puberty
0.000 0.997 0.002
E30.0 Delayed puberty
0.000 0.997 0.002
E31.9 Polyglandular dysfunction, unspecified
0.000 0.997 0.002
E31.8 Other polyglandular dysfunction
0.000 0.997 0.002
E31.1 Polyglandular hyperfunction
0.000 0.997 0.002
E31.0 Autoimmune polyglandular failure
0.000 0.997 0.002
E32.9 Disease of thymus, unspecified
0.000 0.997 0.002
E32.8 Other diseases of thymus
0.000 0.997 0.002
E32.1 Abscess of thymus
0.000 0.997 0.002
E32.0 Persistent hyperplasia of thymus
0.000 0.997 0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.997 0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.997 0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.997 0.002
H18 Other disorders of cornea
0.000 0.997 0.003
E25.9 Adrenogenital disorder, unspecified
0.000 0.997 0.002
E25.8 Other adrenogenital disorders
0.000 0.997 0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.002 0.997 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.002 0.997 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.002 0.997 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.002 0.997 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.002 0.997 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.002 0.997 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.002 0.997 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.002 0.997 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.002 0.997 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.997 0.002
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.997 0.002
E22.8 Other hyperfunction of pituitary gland
0.000 0.997 0.002
D86.9 Sarcoidosis, unspecified
0.000 0.997 0.003
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.000 0.997 0.003
H54.9 Unspecified visual impairment (binocular)
0.000 0.997 0.003
W08 Fall involving other furniture
0.003 0.997 0.000
E34.5 Androgen resistance syndrome
0.000 0.997 0.002
E34.4 Constitutional tall stature
0.000 0.997 0.002
E34.3 Short stature, not elsewhere classified
0.000 0.997 0.002
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.997 0.002
E34.1 Other hypersecretion of intestinal hormones
0.000 0.997 0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.002 0.997 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.997 0.002
E34.8 Other specified endocrine disorders
0.000 0.997 0.002
H18.2 Other corneal oedema
0.000 0.997 0.002
O23.3 Infections of other parts of urinary tract in pregnancy
0.002 0.997 0.000
O23.2 Infections of urethra in pregnancy
0.002 0.997 0.000
O23.1 Infections of bladder in pregnancy
0.002 0.997 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.997 0.002
I87.2 Venous insufficiency (chronic) (peripheral)
0.003 0.997 0.000
M85.4 Solitary bone cyst
0.002 0.997 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.002 0.997 0.000
D86 Sarcoidosis
0.000 0.997 0.003
H18.5 Hereditary corneal dystrophies
0.000 0.998 0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.998 0.002
M85.88 Other specified disorders of bone density and structure (Other)
0.002 0.998 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.002 0.998 0.000
E29 Testicular dysfunction
0.000 0.998 0.002
M85.2 Hyperostosis of skull
0.002 0.998 0.000
S51.8 Open wound of other parts of forearm
0.002 0.998 0.000
E20.8 Other hypoparathyroidism
0.000 0.998 0.002
E20.1 Pseudohypoparathyroidism
0.000 0.998 0.002
E20.0 Idiopathic hypoparathyroidism
0.000 0.998 0.002
K51.8 Other ulcerative colitis
0.002 0.998 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.002 0.998 0.000
D68.2 Hereditary deficiency of other clotting factors
0.002 0.998 0.000
M54.39 Sciatica (Site unspecified)
0.000 0.998 0.002
M85.83 Other specified disorders of bone density and structure (Forearm)
0.002 0.998 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.002 0.998 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.002 0.998 0.000
E26.0 Primary hyperaldosteronism
0.000 0.998 0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.998 0.002
H18.0 Corneal pigmentations and deposits
0.000 0.998 0.002
K42.0 Umbilical hernia with obstruction, without gangrene
0.002 0.998 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.002 0.998 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.002 0.998 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.002 0.998 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.002 0.998 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.002 0.998 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.000 0.998 0.002
M85.5 Aneurysmal bone cyst
0.002 0.998 0.000
M85.3 Osteitis condensans
0.002 0.998 0.000
M85.1 Skeletal fluorosis
0.002 0.998 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.002 0.998 0.000
K66.9 Disorder of peritoneum, unspecified
0.002 0.998 0.000
M85.9 Disorder of bone density and structure, unspecified
0.002 0.998 0.000
W08.9 Unspecified place
0.002 0.998 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.002 0.998 0.000
M50.3 Other cervical disk degeneration
0.002 0.998 0.000
E24 Cushing's syndrome
0.000 0.998 0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.002 0.998 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.002 0.998 0.000
E66 Obesity
0.000 0.998 0.002
R72 Abnormality of white blood cells, not elsewhere classified
0.002 0.998 0.000
H18.7 Other corneal deformities
0.000 0.998 0.002
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.002 0.998 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.002 0.998 0.000
M85.46 Solitary bone cyst (Lower leg)
0.002 0.998 0.000
S62.2 Fracture of first metacarpal bone
0.002 0.998 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.002 0.998 0.000
M85.20 Hyperostosis of skull-Mult sites
0.002 0.998 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.002 0.998 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.998 0.002
W08.8 Other specified place
0.002 0.998 0.000
W08.7 Farm
0.002 0.998 0.000
W08.6 Industrial and construction area
0.002 0.998 0.000
W08.5 Trade and service area
0.002 0.998 0.000
W08.4 Street and highway
0.002 0.998 0.000
W08.3 Sports and athletics area
0.002 0.998 0.000
W08.2 School, other institution and public administrative area
0.002 0.998 0.000
W08.1 Residential institution
0.002 0.998 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.998 0.002
E27.8 Other specified disorders of adrenal gland
0.000 0.998 0.002
H18.8 Other specified disorders of cornea
0.000 0.998 0.002
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.002 0.998 0.000
J42 Unspecified chronic bronchitis
0.002 0.998 0.000
M85.49 Solitary bone cyst (Site unspecified)
0.002 0.998 0.000
M85.48 Solitary bone cyst (Other)
0.002 0.998 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.002 0.998 0.000
M85.44 Solitary bone cyst (Hand)
0.002 0.998 0.000
M85.43 Solitary bone cyst (Forearm)
0.002 0.998 0.000
M85.42 Solitary bone cyst (Upper arm)
0.002 0.998 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.002 0.998 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.002 0.998 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.002 0.998 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.000 0.998 0.002
T83.2 Mechanical complication of graft of urinary organ
0.002 0.998 0.000
H18.9 Disorder of cornea, unspecified
0.000 0.998 0.002
M06.98 Rheumatoid arthritis, unspecified (Other)
0.002 0.998 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.998 0.002
E29.8 Other testicular dysfunction
0.000 0.998 0.002
E29.0 Testicular hyperfunction
0.000 0.998 0.002
E34.0 Carcinoid syndrome
0.000 0.998 0.002
M85.29 Hyperostosis of skull-Site unspec
0.002 0.998 0.000
M85.28 Hyperostosis of skull-Other
0.002 0.998 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.002 0.998 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.002 0.998 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.002 0.998 0.000
M85.24 Hyperostosis of skull-Hand
0.002 0.998 0.000
M85.23 Hyperostosis of skull-Forearm
0.002 0.998 0.000
M85.22 Hyperostosis of skull-Upper arm
0.002 0.998 0.000
M85.21 Hyperostosis of skull-Shldr region
0.002 0.998 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.998 0.002
O02.0 Blighted ovum and nonhydatidiform mole
0.002 0.998 0.000
E28 Ovarian dysfunction
0.000 0.998 0.002
J40-J47 Chronic lower respiratory diseases
0.002 0.998 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.998 0.002
L53.8 Other specified erythematous conditions
0.000 0.998 0.002
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.002 0.998 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.000 0.998 0.002
C21 Malignant neoplasm of anus and anal canal
0.000 0.998 0.002
M85.19 Skeletal fluorosis (Site unspecified)
0.002 0.998 0.000
M85.18 Skeletal fluorosis (Other)
0.002 0.998 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.002 0.998 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.002 0.998 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.002 0.998 0.000
M85.14 Skeletal fluorosis (Hand)
0.002 0.998 0.000
M85.13 Skeletal fluorosis (Forearm)
0.002 0.998 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.002 0.998 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.002 0.998 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.002 0.998 0.000
M85.39 Osteitis condensans (Site unspecified)
0.002 0.998 0.000
M85.38 Osteitis condensans (Other)
0.002 0.998 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.002 0.998 0.000
M85.36 Osteitis condensans (Lower leg)
0.002 0.998 0.000
M85.35 Osteitis condensans (Pelvic region and thigh)
0.002 0.998 0.000
M85.34 Osteitis condensans (Hand)
0.002 0.998 0.000
M85.33 Osteitis condensans (Forearm)
0.002 0.998 0.000
M85.32 Osteitis condensans (Upper arm)
0.002 0.998 0.000
M85.31 Osteitis condensans (Shoulder region)
0.002 0.998 0.000
M85.30 Osteitis condensans (Multiple sites)
0.002 0.998 0.000
M85.59 Aneurysmal bone cyst (Site unspecified)
0.002 0.998 0.000
M85.58 Aneurysmal bone cyst (Other)
0.002 0.998 0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)
0.002 0.998 0.000
M85.56 Aneurysmal bone cyst (Lower leg)
0.002 0.998 0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)
0.002 0.998 0.000
M85.54 Aneurysmal bone cyst (Hand)
0.002 0.998 0.000
M85.53 Aneurysmal bone cyst (Forearm)
0.002 0.998 0.000
M85.52 Aneurysmal bone cyst (Upper arm)
0.002 0.998 0.000
M85.51 Aneurysmal bone cyst (Shoulder region)
0.002 0.998 0.000
M85.50 Aneurysmal bone cyst (Multiple sites)
0.002 0.998 0.000
D86.3 Sarcoidosis of skin
0.000 0.998 0.002
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.998 0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.002 0.998 0.000
L53 Other erythematous conditions
0.000 0.998 0.002
M85.98 Disorder of bone density and structure, unspecified (Other)
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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