TreeWAS – Variant ID: rs6546355

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.000	1.000
I69.3 Sequelae of cerebral infarction	0.728	0.272	0.000
I69 Sequelae of cerebrovascular disease	0.721	0.279	0.000
I60-I69 Cerebrovascular diseases	0.716	0.284	0.000
I60 Subarachnoid haemorrhage	0.714	0.286	0.000
I83 Varicose veins of lower extremities	0.000	0.287	0.713
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.307	0.693
I61 Intracerebral haemorrhage	0.692	0.308	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.690	0.310	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.656	0.344	0.000
I63 Cerebral infarction	0.647	0.353	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.644	0.356	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.612	0.388	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.598	0.401	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.587	0.413	0.000
I60.8 Other subarachnoid haemorrhage	0.587	0.413	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.586	0.414	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.571	0.428	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.564	0.436	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.562	0.438	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.559	0.441	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.538	0.462	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.535	0.465	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.530	0.470	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.529	0.471	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.525	0.475	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.523	0.477	0.000
I67 Other cerebrovascular diseases	0.521	0.479	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.516	0.484	0.000
I63.8 Other cerebral infarction	0.513	0.487	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.512	0.488	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.486	0.514	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.473	0.527	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.473	0.527	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.470	0.530	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.464	0.536	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.464	0.536	0.000
I67.9 Cerebrovascular disease, unspecified	0.462	0.538	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.457	0.543	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.457	0.543	0.000
I61.8 Other intracerebral haemorrhage	0.455	0.544	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.448	0.552	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.559	0.441
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.439	0.561	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.434	0.566	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.421	0.579	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.417	0.583	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.409	0.591	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.403	0.597	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.403	0.597	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.403	0.597	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.403	0.597	0.000
I67.2 Cerebral atherosclerosis	0.392	0.608	0.000
I68.0 Cerebral amyloid angiopathy	0.387	0.612	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.378	0.621	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.376	0.624	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.376	0.624	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.376	0.624	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.376	0.624	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.374	0.626	0.000
I67.5 Moyamoya disease	0.374	0.626	0.000
I67.4 Hypertensive encephalopathy	0.374	0.626	0.000
I67.3 Progressive vascular leukoencephalopathy	0.374	0.626	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.371	0.629	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.364	0.636	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.364	0.636	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.328	0.672	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.311	0.688	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.311	0.688	0.000
I67.1 Cerebral aneurysm, nonruptured	0.309	0.691	0.000
I63.9 Cerebral infarction, unspecified	0.300	0.700	0.000
I65.1 Occlusion and stenosis of basilar artery	0.290	0.710	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.001	0.716	0.283
I62 Other nontraumatic intracranial haemorrhage	0.265	0.734	0.000
I67.8 Other specified cerebrovascular diseases	0.244	0.756	0.000
I62.1 Nontraumatic extradural haemorrhage	0.184	0.815	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.132	0.868	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.097	0.903	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.088	0.912	0.000
I65.2 Occlusion and stenosis of carotid artery	0.087	0.913	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.967	0.033
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.971	0.029
I88 Nonspecific lymphadenitis	0.000	0.971	0.029
I86 Varicose veins of other sites	0.000	0.972	0.028
I86.8 Varicose veins of other specified sites	0.000	0.973	0.027
I89.0 Lymphoedema, not elsewhere classified	0.000	0.974	0.026
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.975	0.025
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.976	0.024
I86.2 Pelvic varices	0.000	0.977	0.023
I89.1 Lymphangitis	0.000	0.978	0.022
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.978	0.022
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.979	0.021
I85 Oesophageal varices	0.000	0.979	0.021
I86.0 Sublingual varices	0.000	0.979	0.020
I88.8 Other nonspecific lymphadenitis	0.000	0.980	0.020
I86.3 Vulval varices	0.000	0.980	0.020
C16.9 Stomach, unspecified	0.020	0.980	0.000
I81 Portal vein thrombosis	0.000	0.981	0.019
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.018	0.982	0.000
I86.1 Scrotal varices	0.000	0.982	0.017
C16 Malignant neoplasm of stomach	0.016	0.984	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.984	0.016
I87 Other disorders of veins	0.000	0.984	0.016
C16.2 Body of stomach	0.015	0.985	0.000
N39.4 Other specified urinary incontinence	0.015	0.985	0.000
C16.3 Pyloric antrum	0.014	0.986	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.986	0.014
C16.6 Greater curvature of stomach, unspecified	0.014	0.986	0.000
I86.4 Gastric varices	0.000	0.987	0.013
M25.6 Stiffness of joint, not elsewhere classified	0.013	0.987	0.000
C16.8 Overlapping lesion of stomach	0.013	0.987	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.987	0.013
C16.5 Lesser curvature of stomach, unspecified	0.012	0.988	0.000
C50.8 Overlapping lesion of breast	0.012	0.988	0.000
C16.1 Fundus of stomach	0.012	0.988	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.012	0.988	0.000
I87.0 Postphlebitic syndrome	0.000	0.988	0.011
C16.4 Pylorus	0.011	0.989	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
I87.9 Disorder of vein, unspecified	0.000	0.989	0.011
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.011	0.989	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.990	0.010
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.010	0.990	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.010	0.990	0.000
C16.0 Cardia	0.009	0.991	0.000
I87.1 Compression of vein	0.000	0.991	0.009
Z57.2 Occupational exposure to dust	0.000	0.991	0.009
I82 Other venous embolism and thrombosis	0.000	0.991	0.009
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.009	0.991	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.009	0.991	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.008	0.991	0.000
N39.0 Urinary tract infection, site not specified	0.008	0.992	0.000
N39 Other disorders of urinary system	0.007	0.993	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.007	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
I82.1 Thrombophlebitis migrans	0.000	0.993	0.006
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
N39.8 Other specified disorders of urinary system	0.006	0.994	0.000
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.994	0.000
I87.8 Other specified disorders of veins	0.000	0.994	0.006
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
I82.0 Budd-Chiari syndrome	0.000	0.994	0.006
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
T50.8 Diagnostic agents	0.006	0.994	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.994	0.006
Z01.6 Radiological examination, not elsewhere classified	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.994	0.005
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.994	0.005
T43.6 Psychostimulants with abuse potential	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
N39.2 Orthostatic proteinuria, unspecified	0.005	0.994	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.005	0.995	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.995	0.005
T36.4 Tetracyclines	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.995	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
Q39.4 Oesophageal web	0.005	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T50.5 Appetite depressants	0.005	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
N39.3 Stress incontinence	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.995	0.005
Q39 Congenital malformations of oesophagus	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
N39.1 Persistent proteinuria, unspecified	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
Q21.1 Atrial septal defect	0.005	0.995	0.000
Q05 Spina bifida	0.005	0.995	0.000
T36.0 Penicillins	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
Q66 Congenital deformities of feet	0.005	0.995	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.995	0.000
T37.5 Antiviral drugs	0.004	0.995	0.000
T37.4 Anthelminthics	0.004	0.995	0.000
T37.3 Other antiprotozoal drugs	0.004	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.995	0.000
T37.1 Antimycobacterial drugs	0.004	0.995	0.000
T37.0 Sulphonamides	0.004	0.995	0.000
C71.2 Temporal lobe	0.005	0.995	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.004	0.995	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.995	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.996	0.004
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.996	0.004
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
C71.9 Brain, unspecified	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
C71.4 Occipital lobe	0.004	0.996	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.996	0.004
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q45.8 Other specified congenital malformations of digestive system	0.004	0.996	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.996	0.004
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.996	0.000
Q39.8 Other congenital malformations of oesophagus	0.004	0.996	0.000
Q39.5 Congenital dilatation of oesophagus	0.004	0.996	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.004	0.996	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.004	0.996	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.004	0.996	0.000
Q39.0 Atresia of oesophagus without fistula	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.996	0.004
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.996	0.004
T45.5 Anticoagulants	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
S82.31 Fracture of lower end of tibia (open)	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
K52.1 Toxic gastro-enteritis and colitis	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q03 Congenital hydrocephalus	0.004	0.996	0.000
Q01 Encephalocele	0.004	0.996	0.000
Q00 Anencephaly and similar malformations	0.004	0.996	0.000
Q02 Microcephaly	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.996	0.004
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.996	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.996	0.000
Q40.1 Congenital hiatus hernia	0.003	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.996	0.000
Q04 Other congenital malformations of brain	0.003	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
W29.9 Unspecified place	0.004	0.996	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.996	0.000
Q66.5 Congenital pes planus	0.003	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.996	0.000
Q66.1 Talipes calcaneovarus	0.003	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.996	0.000
Q66.0 Talipes equinovarus	0.003	0.996	0.000
Q07 Other congenital malformations of nervous system	0.003	0.996	0.000
Q44.7 Other congenital malformations of liver	0.003	0.996	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.996	0.000
Q44.4 Choledochal cyst	0.003	0.996	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.996	0.000
Q44.2 Atresia of bile ducts	0.003	0.996	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.996	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.996	0.000
Q66.2 Metatarsus varus	0.003	0.996	0.000
Q80-Q89 Other congenital malformations	0.003	0.996	0.000
D09.0 Bladder	0.003	0.996	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.997	0.003
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.997	0.000
Q06.4 Hydromyelia	0.003	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.997	0.000
Q06.2 Diastematomyelia	0.003	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.997	0.000
Q06.0 Amyelia	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
Q10.0 Congenital ptosis	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations