TreeWAS – Variant ID: rs66525318

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
C44.3 Skin of other and unspecified parts of face	1.000	0.000	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
K51 Ulcerative colitis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
K50-K52 Noninfective enteritis and colitis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
K50 Crohn's disease [regional enteritis]	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
M06.0 Seronegative rheumatoid arthritis	1.000	0.000	0.000
K50.1 Crohn's disease of large intestine	1.000	0.000	0.000
Z93.2 Ileostomy status	0.999	0.001	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
C44.5 Skin of trunk	0.999	0.001	0.000
C44.2 Skin of ear and external auricular canal	0.998	0.002	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.002	0.998
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.998	0.002	0.000
K51.4 Pseudopolyposis of colon	0.998	0.002	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.998	0.002	0.000
C44.7 Skin of lower limb, including hip	0.997	0.003	0.000
M05 Seropositive rheumatoid arthritis	0.995	0.005	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.995	0.005	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.994	0.006	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.992	0.008	0.000
M45 Ankylosing spondylitis	0.992	0.008	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.992	0.008	0.000
M45-M49 Spondylopathies	0.992	0.008	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.991	0.009	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.991	0.009	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.990	0.010	0.000
L40-L45 Papulosquamous disorders	0.989	0.011	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.989	0.011	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.988	0.012	0.000
C73 Malignant neoplasm of thyroid gland	0.987	0.013	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.013	0.987
L57.0 Actinic keratosis	0.986	0.014	0.000
C44.1 Skin of eyelid, including canthus	0.985	0.015	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.015	0.985
# Top node	0.985	0.015	0.000
C83.3 Large cell (diffuse)	0.984	0.016	0.000
D86 Sarcoidosis	0.000	0.017	0.983
D86.9 Sarcoidosis, unspecified	0.000	0.018	0.982
L43 Lichen planus	0.979	0.020	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.021	0.979
E10.3 With ophthalmic complications	0.000	0.026	0.974
M07 Psoriatic and enteropathic arthropathies	0.973	0.027	0.000
E27 Other disorders of adrenal gland	0.000	0.027	0.973
L43.9 Lichen planus, unspecified	0.971	0.029	0.000
K50.9 Crohn's disease, unspecified	0.967	0.033	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.966	0.034	0.000
D80-D89 Certain disorders involving the immune mechanism	0.010	0.035	0.954
D86.0 Sarcoidosis of lung	0.000	0.036	0.964
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.015	0.036	0.949
E27.1 Primary adrenocortical insufficiency	0.000	0.039	0.961
D50-D53 Nutritional anaemias	0.002	0.040	0.959
D51 Vitamin B12 deficiency anaemia	0.000	0.041	0.959
Chapter XI Diseases of the digestive system	0.959	0.041	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.958	0.042	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.957	0.043	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.045	0.955
M07.3 Other psoriatic arthropathies	0.955	0.045	0.000
K90 Intestinal malabsorption	0.015	0.046	0.939
K51.8 Other ulcerative colitis	0.951	0.049	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.049	0.951
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.951	0.049	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.051	0.949
E10.1 With ketoacidosis	0.000	0.061	0.939
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.932	0.068	0.000
L03 Cellulitis	0.932	0.068	0.000
C44.4 Skin of scalp and neck	0.928	0.072	0.000
L40 Psoriasis	0.925	0.075	0.000
C82.0 Small cleaved cell, follicular	0.924	0.076	0.000
L40.5 Arthropathic psoriasis	0.922	0.078	0.000
E21.0 Primary hyperparathyroidism	0.000	0.081	0.919
K51.2 Ulcerative (chronic) proctitis	0.918	0.082	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.917	0.083	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.087	0.913
L03.2 Cellulitis of face	0.913	0.087	0.000
C44.0 Skin of lip	0.910	0.090	0.000
K90-K93 Other diseases of the digestive system	0.895	0.092	0.013
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.900	0.100	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.895	0.105	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.106	0.894
D50 Iron deficiency anaemia	0.000	0.106	0.894
C02.1 Border of tongue	0.892	0.108	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.885	0.114	0.001
D50.9 Iron deficiency anaemia, unspecified	0.000	0.114	0.886
K91.4 Colostomy and enterostomy malfunction	0.882	0.118	0.000
L03.0 Cellulitis of finger and toe	0.882	0.118	0.000
M65-M68 Disorders of synovium and tendon	0.881	0.119	0.000
E14 Unspecified diabetes mellitus	0.000	0.119	0.881
D86.8 Sarcoidosis of other and combined sites	0.000	0.126	0.874
E16.2 Hypoglycaemia, unspecified	0.000	0.130	0.870
C02.9 Tongue, unspecified	0.865	0.135	0.000
K90.9 Intestinal malabsorption, unspecified	0.004	0.137	0.859
C85.1 B-cell lymphoma, unspecified	0.861	0.139	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.005	0.141	0.854
M46 Other inflammatory spondylopathies	0.855	0.145	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.854	0.146	0.000
C82.3 Follicular lymphoma grade IIIa	0.847	0.153	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.841	0.159	0.000
M06.3 Rheumatoid nodule	0.840	0.160	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.840	0.160	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.838	0.162	0.000
K51.5 Mucosal proctocolitis	0.835	0.165	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.829	0.171	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.825	0.175	0.000
L03.8 Cellulitis of other sites	0.824	0.176	0.000
C44.6 Skin of upper limb, including shoulder	0.824	0.176	0.000
E14.9 Without complications	0.000	0.178	0.822
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.821	0.179	0.000
C43 Malignant melanoma of skin	0.820	0.180	0.000
C74 Malignant neoplasm of adrenal gland	0.817	0.183	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.814	0.186	0.000
M00-M03 Infectious arthropathies	0.813	0.187	0.000
L42 Pityriasis rosea	0.812	0.188	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.811	0.189	0.000
E10.8 With unspecified complications	0.000	0.191	0.809
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.808	0.192	0.000
C82.4 Follicular lymphoma grade IIIb	0.807	0.193	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.806	0.194	0.000
E22 Hyperfunction of pituitary gland	0.000	0.200	0.800
E27.2 Addisonian crisis	0.000	0.202	0.798
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.798	0.202	0.000
D52 Folate deficiency anaemia	0.001	0.205	0.794
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.793	0.207	0.000
D55-D59 Haemolytic anaemias	0.010	0.208	0.782
C03 Malignant neoplasm of gum	0.791	0.208	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.791	0.209	0.000
C02.2 Ventral surface of tongue	0.790	0.209	0.000
C05 Malignant neoplasm of palate	0.790	0.210	0.000
C06.0 Cheek mucosa	0.788	0.212	0.000
L57.4 Cutis laxa senilis	0.787	0.213	0.000
C83.1 Small cleaved cell (diffuse)	0.787	0.213	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.783	0.217	0.000
C10 Malignant neoplasm of oropharynx	0.782	0.218	0.000
C82.2 Large cell, follicular	0.778	0.222	0.000
E20 Hypoparathyroidism	0.000	0.223	0.777
E65-E68 Obesity and other hyperalimentation	0.000	0.224	0.776
C40-C41 Malignant neoplasms of bone and articular cartilage	0.776	0.224	0.000
L43.8 Other lichen planus	0.774	0.226	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.769	0.231	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.769	0.231	0.000
E10.5 With peripheral circulatory complications	0.000	0.234	0.766
E10.0 With coma	0.000	0.235	0.765
M65 Synovitis and tenosynovitis	0.765	0.235	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.236	0.764
C44.9 Malignant neoplasm of skin, unspecified	0.762	0.238	0.000
M60-M63 Disorders of muscles	0.755	0.245	0.000
L10-L14 Bullous disorders	0.755	0.245	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.751	0.249	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.744	0.255	0.000
M66 Spontaneous rupture of synovium and tendon	0.744	0.256	0.000
M49 Spondylopathies in diseases classified elsewhere	0.739	0.261	0.000
M11 Other crystal arthropathies	0.738	0.262	0.000
E03.8 Other specified hypothyroidism	0.000	0.263	0.737
C06.9 Mouth, unspecified	0.736	0.264	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.735	0.264	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.266	0.734
E40-E46 Malnutrition	0.000	0.268	0.732
C75 Malignant neoplasm of other endocrine glands and related structures	0.731	0.269	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.726	0.274	0.000
E13 Other specified diabetes mellitus	0.000	0.275	0.725
E21.3 Hyperparathyroidism, unspecified	0.000	0.276	0.724
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.722	0.278	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.721	0.278	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.279	0.721
L01 Impetigo	0.721	0.279	0.000
K65-K67 Diseases of peritoneum	0.720	0.280	0.000
E10.6 With other specified complications	0.000	0.281	0.719
M65.9 Synovitis and tenosynovitis, unspecified	0.719	0.281	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.718	0.282	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.283	0.717
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
C82.6 Cutaneous follicle centre lymphoma	0.717	0.283	0.000
C82.5 Diffuse follicle centre lymphoma	0.717	0.283	0.000
E10.7 With multiple complications	0.000	0.283	0.717
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
C93 Monocytic leukaemia	0.717	0.283	0.000
C86 Other specified types of T/NK-cell lymphoma	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
M06.08 Seronegative rheumatoid arthritis (Other)	0.717	0.283	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.717	0.283	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.717	0.283	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.717	0.283	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.717	0.283	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.717	0.283	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.717	0.283	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.284	0.716
E03.1 Congenital hypothyroidism without goitre	0.000	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.284	0.716
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.715	0.284	0.000
C85.0 Lymphosarcoma	0.715	0.284	0.000
K50.8 Other Crohn's disease	0.714	0.286	0.000
M05.8 Other seropositive rheumatoid arthritis	0.714	0.286	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.714	0.286	0.000
M05.2 Rheumatoid vasculitis	0.714	0.286	0.000
M05.1 Rheumatoid lung disease	0.714	0.286	0.000
M05.0 Felty's syndrome	0.714	0.286	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.713	0.287	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.711	0.288	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.711	0.288	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.711	0.288	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.711	0.288	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.711	0.288	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.711	0.288	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.711	0.288	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.711	0.289	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.711	0.289	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.711	0.289	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.711	0.289	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.711	0.289	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.711	0.289	0.000
D59 Acquired haemolytic anaemia	0.005	0.289	0.706
C83.7 Burkitt's tumour	0.710	0.290	0.000
C83.6 Undifferentiated (diffuse)	0.710	0.290	0.000
C83.5 Lymphoblastic (diffuse)	0.710	0.290	0.000
C83.4 Immunoblastic (diffuse)	0.710	0.290	0.000
C83.2 Mixed small and large cell (diffuse)	0.710	0.290	0.000
C13 Malignant neoplasm of hypopharynx	0.709	0.290	0.000
C11 Malignant neoplasm of nasopharynx	0.709	0.290	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.709	0.290	0.000
C00 Malignant neoplasm of lip	0.709	0.290	0.000
C12 Malignant neoplasm of pyriform sinus	0.709	0.290	0.000
E24 Cushing's syndrome	0.000	0.291	0.709
L44 Other papulosquamous disorders	0.709	0.291	0.000
L41 Parapsoriasis	0.709	0.291	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.709	0.291	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.709	0.291	0.000
L58 Radiodermatitis	0.709	0.291	0.000
L55 Sunburn	0.709	0.291	0.000
C43.4 Malignant melanoma of scalp and neck	0.709	0.291	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.708	0.292	0.000
L57.5 Actinic granuloma	0.708	0.292	0.000
L57.3 Poikiloderma of Civatte	0.708	0.292	0.000
L57.2 Cutis rhomboidalis nuchae	0.708	0.292	0.000
L57.1 Actinic reticuloid	0.708	0.292	0.000
E16.1 Other hypoglycaemia	0.000	0.292	0.708
M06.34 Rheumatoid nodule (Hand)	0.708	0.292	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.292	0.708
E05.5 Thyroid crisis or storm	0.000	0.293	0.707
E05.4 Thyrotoxicosis factitia	0.000	0.293	0.707
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.293	0.707
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.293	0.707
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.707	0.293	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.293	0.706
E32 Diseases of thymus	0.000	0.293	0.706
E31 Polyglandular dysfunction	0.000	0.293	0.706
E30 Disorders of puberty, not elsewhere classified	0.000	0.293	0.706
Chapter XVI Certain conditions originating in the perinatal period	0.706	0.294	0.000
E05.8 Other thyrotoxicosis	0.000	0.294	0.706
D86.3 Sarcoidosis of skin	0.000	0.295	0.705
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.295	0.705
D86.1 Sarcoidosis of lymph nodes	0.000	0.295	0.705
M06.4 Inflammatory polyarthropathy	0.705	0.295	0.000
L43.3 Subacute (active) lichen planus	0.702	0.298	0.000
L43.2 Lichenoid drug reaction	0.702	0.298	0.000
L43.1 Bullous lichen planus	0.702	0.298	0.000
L43.0 Hypertrophic lichen planus	0.702	0.298	0.000
C02.4 Lingual tonsil	0.702	0.298	0.000
E10.4 With neurological complications	0.000	0.299	0.701
L56 Other acute skin changes due to ultraviolet radiation	0.700	0.300	0.000
M14 Arthropathies in other diseases classified elsewhere	0.699	0.301	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.697	0.302	0.001
M07.6 Other enteropathic arthropathies	0.698	0.302	0.000
M07.5 Arthropathy in ulcerative colitis	0.698	0.302	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.698	0.302	0.000
M07.2 Psoriatic spondylitis	0.698	0.302	0.000
M07.1 Arthritis mutilans	0.698	0.302	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.698	0.302	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.302	0.698
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.302	0.698
E27.0 Other adrenocortical overactivity	0.000	0.302	0.698
L04 Acute lymphadenitis	0.697	0.303	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.695	0.305	0.000
C02.8 Overlapping lesion of tongue	0.692	0.307	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.692	0.307	0.000
C02.0 Dorsal surface of tongue	0.692	0.307	0.000
D82 Immunodeficiency associated with other major defects	0.008	0.308	0.684
D81 Combined immunodeficiencies	0.008	0.308	0.684
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.692	0.308	0.000
M91-M94 Chondropathies	0.691	0.309	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.312	0.687
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.312	0.687
D51.2 Transcobalamin II deficiency	0.000	0.312	0.687
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.312	0.687
L00 Staphylococcal scalded skin syndrome	0.686	0.314	0.000
M07.38 Other psoriatic arthropathies (Other)	0.684	0.316	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.684	0.316	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.684	0.316	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.684	0.316	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.684	0.316	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.684	0.316	0.000
K90.3 Pancreatic steatorrhoea	0.011	0.316	0.673
K90.2 Blind loop syndrome, not elsewhere classified	0.011	0.316	0.673
K90.1 Tropical sprue	0.011	0.316	0.673
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.318	0.682
E21.4 Other specified disorders of parathyroid gland	0.000	0.318	0.682
E21.2 Other hyperparathyroidism	0.000	0.318	0.682
E15 Nondiabetic hypoglycaemic coma	0.000	0.319	0.681
E66 Obesity	0.000	0.320	0.680
M46.1 Sacro-iliitis, not elsewhere classified	0.679	0.321	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.324	0.676
M80-M85 Disorders of bone density and structure	0.676	0.324	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.674	0.326	0.000
C88 Malignant immunoproliferative diseases	0.674	0.326	0.000
D53 Other nutritional anaemias	0.001	0.326	0.672
C05.0 Hard palate	0.673	0.327	0.000
Chapter V Mental and behavioural disorders	0.673	0.327	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.672	0.327	0.000
C04 Malignant neoplasm of floor of mouth	0.672	0.328	0.000
M00 Pyogenic arthritis	0.671	0.329	0.000
M46.2 Osteomyelitis of vertebra	0.669	0.331	0.000
K90.8 Other intestinal malabsorption	0.011	0.331	0.658
C81 Hodgkin's disease	0.666	0.334	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.664	0.336	0.000
L40.4 Guttate psoriasis	0.663	0.337	0.000
L40.3 Pustulosis palmaris et plantaris	0.663	0.337	0.000
L40.2 Acrodermatitis continua	0.663	0.337	0.000
L40.1 Generalised pustular psoriasis	0.663	0.337	0.000
C09 Malignant neoplasm of tonsil	0.662	0.338	0.000
E10.2 With renal complications	0.000	0.338	0.661
E50-E64 Other nutritional deficiencies	0.000	0.339	0.661
E27.9 Disorder of adrenal gland, unspecified	0.000	0.340	0.660
D80 Immunodeficiency with predominantly antibody defects	0.007	0.340	0.652
C74.0 Cortex of adrenal gland	0.657	0.343	0.000
C01 Malignant neoplasm of base of tongue	0.655	0.345	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.345	0.655
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.345	0.655
E16.4 Abnormal secretion of gastrin	0.000	0.345	0.655
E16.3 Increased secretion of glucagon	0.000	0.345	0.655
E29 Testicular dysfunction	0.000	0.347	0.653
D59.1 Other autoimmune haemolytic anaemias	0.002	0.347	0.651
E05.9 Thyrotoxicosis, unspecified	0.000	0.348	0.652
K93 Disorders of other digestive organs in diseases classified elsewhere	0.642	0.349	0.010
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.349	0.651
C03.1 Lower gum	0.649	0.350	0.000
C84.4 Peripheral T-cell lymphoma	0.648	0.352	0.000
Chapter XXII Codes for special purposes	0.648	0.352	0.000
E66.9 Obesity, unspecified	0.000	0.352	0.648
M06.37 Rheumatoid nodule (Ankle and foot)	0.645	0.355	0.000
C95 Leukaemia of unspecified cell type	0.644	0.356	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.642	0.358	0.000
C06.2 Retromolar area	0.642	0.358	0.000
C06.1 Vestibule of mouth	0.642	0.358	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.642	0.358	0.000
D50.1 Sideropenic dysphagia	0.000	0.359	0.641
K91.5 Postcholecystectomy syndrome	0.634	0.365	0.001
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.635	0.365	0.000
C74.9 Adrenal gland, unspecified	0.634	0.366	0.000
C10.9 Oropharynx, unspecified	0.633	0.366	0.000
E07 Other disorders of thyroid	0.000	0.367	0.633
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.632	0.368	0.000
M46.4 Discitis, unspecified	0.632	0.368	0.000
E14.8 With unspecified complications	0.000	0.368	0.632
E14.7 With multiple complications	0.000	0.368	0.632
E14.6 With other specified complications	0.000	0.368	0.632
E14.5 With peripheral circulatory complications	0.000	0.368	0.632
E14.2 Withrenal complications	0.000	0.368	0.632
E14.1 With ketoacidosis	0.000	0.368	0.632
E14.0 With coma	0.000	0.368	0.632
C84.5 Other and unspecified T-cell lymphomas	0.628	0.372	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.372	0.628
K91.1 Postgastric surgery syndromes	0.625	0.374	0.001
E27.8 Other specified disorders of adrenal gland	0.000	0.378	0.622
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.619	0.381	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.615	0.385	0.000
E34 Other endocrine disorders	0.000	0.385	0.615
M46.8 Other specified inflammatory spondylopathies	0.613	0.387	0.000
M46.5 Other infective spondylopathies	0.613	0.387	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.613	0.387	0.000
M46.0 Spinal enthesopathy	0.613	0.387	0.000
M66.2 Spontaneous rupture of extensor tendons	0.610	0.390	0.000
D83 Common variable immunodeficiency	0.009	0.390	0.601
M40-M43 Deforming dorsopathies	0.609	0.391	0.000
E25 Adrenogenital disorders	0.000	0.394	0.606
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.007	0.396	0.597
M06.39 Rheumatoid nodule (Site unspecified)	0.602	0.397	0.000
M06.38 Rheumatoid nodule (Other)	0.602	0.397	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.602	0.397	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.602	0.397	0.000
M06.33 Rheumatoid nodule (Forearm)	0.602	0.397	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.602	0.397	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.602	0.397	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.602	0.398	0.000
M66.3 Spontaneous rupture of flexor tendons	0.602	0.398	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.601	0.399	0.000
M02 Reactive arthropathies	0.601	0.399	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.599	0.400	0.001
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.600	0.400	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.597	0.403	0.000
E14.4 With neurological complications	0.000	0.409	0.591
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.590	0.410	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.590	0.410	0.000
L08 Other local infections of skin and subcutaneous tissue	0.590	0.410	0.000
C43.8 Overlapping malignant melanoma of skin	0.588	0.412	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.588	0.412	0.000
C43.0 Malignant melanoma of lip	0.588	0.412	0.000
M62 Other disorders of muscle	0.587	0.413	0.000
L12 Pemphigoid	0.586	0.414	0.000
C74.1 Medulla of adrenal gland	0.586	0.414	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.583	0.416	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.583	0.416	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.583	0.416	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.583	0.416	0.000
C84.3 Lymphoepithelioid lymphoma	0.583	0.416	0.000
C84.2 T-zone lymphoma	0.583	0.416	0.000
C84.1 Sezary's diease	0.583	0.416	0.000
C84.0 Mycosis fungoides	0.583	0.416	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.583	0.417	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.583	0.417	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.581	0.419	0.000
C69 Malignant neoplasm of eye and adnexa	0.580	0.420	0.000
M85 Other disorders of bone density and structure	0.578	0.422	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.426	0.573
E22.8 Other hyperfunction of pituitary gland	0.000	0.426	0.573
M65.1 Other infective (teno)synovitis	0.573	0.427	0.000
M11.9 Crystal arthropathy, unspecified	0.573	0.427	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.573	0.427	0.000
E14.3 With ophthalmic complications	0.000	0.428	0.572
D52.8 Other folate deficiency anaemias	0.001	0.430	0.569
D52.1 Drug-induced folate deficiency anaemia	0.001	0.430	0.569
D52.0 Dietary folate deficiency anaemia	0.001	0.430	0.569
M00.9 Pyogenic arthritis, unspecified	0.570	0.430	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.569	0.430	0.001
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.569	0.431	0.000
D57 Sickle-cell disorders	0.008	0.432	0.561
D55 Anaemia due to enzyme disorders	0.008	0.432	0.561
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.568	0.432	0.000
F30-F39 Mood [affective] disorders	0.568	0.432	0.000
C03.9 Gum, unspecified	0.567	0.432	0.000
C03.0 Upper gum	0.567	0.432	0.000
C05.9 Palate, unspecified	0.566	0.433	0.000
C05.8 Overlapping lesion of palate	0.566	0.433	0.000
C05.2 Uvula	0.566	0.433	0.000
M67 Other disorders of synovium and tendon	0.567	0.433	0.000
K65 Peritonitis	0.566	0.434	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.561	0.438	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.561	0.439	0.000
C10.8 Overlapping lesion of oropharynx	0.561	0.439	0.000
C10.4 Branchial cleft	0.561	0.439	0.000
C10.3 Posterior wall of oropharynx	0.561	0.439	0.000
C10.2 Lateral wall of oropharynx	0.561	0.439	0.000
C10.1 Anterior surface of epiglottis	0.561	0.439	0.000
C10.0 Vallecula	0.561	0.439	0.000
E06 Thyroiditis	0.000	0.441	0.559
D84 Other immunodeficiencies	0.009	0.442	0.549
M49.5 Collapsed vertebra in diseases classified elsewhere	0.558	0.442	0.000
E20.8 Other hypoparathyroidism	0.000	0.443	0.557
E20.1 Pseudohypoparathyroidism	0.000	0.443	0.557
E20.0 Idiopathic hypoparathyroidism	0.000	0.443	0.557
E67 Other hyperalimentation	0.000	0.443	0.556
E68 Sequelae of hyperalimentation	0.000	0.443	0.556
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.556	0.444	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.556	0.444	0.000
M65.8 Other synovitis and tenosynovitis	0.554	0.446	0.000
C81.1 Nodular sclerosis	0.553	0.447	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.552	0.448	0.000
C07 Malignant neoplasm of parotid gland	0.551	0.448	0.000
C83.0 Small cell (diffuse)	0.552	0.448	0.000
L01.0 Impetigo [any organism] [any site]	0.552	0.448	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.552	0.448	0.000
M80 Osteoporosis with pathological fracture	0.551	0.449	0.000
K52 Other non-infective gastro-enteritis and colitis	0.551	0.449	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.550	0.449	0.000
M65.2 Calcific tendinitis	0.548	0.451	0.000
M65.0 Abscess of tendon sheath	0.548	0.451	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.546	0.454	0.000
L40.8 Other psoriasis	0.545	0.455	0.000
C43.9 Malignant melanoma of skin, unspecified	0.544	0.456	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations