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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6656088
log Bayes Factor = 5.87242
Chromosome 1   position 225,909,815  (GRCh37) Explore rs6656088 on Ensembl!
Variant rs6656088 is part of Cluster X0162

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
K70-K77 Diseases of liver
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.990 0.010 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.990 0.010 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.980 0.020 0.000
K70 Alcoholic liver disease
0.980 0.020 0.000
Chapter VI Diseases of the nervous system
0.973 0.027 0.000
D68 Other coagulation defects
0.971 0.029 0.000
K80 Cholelithiasis
0.964 0.036 0.000
K22 Other diseases of oesophagus
0.963 0.037 0.000
K22.7 Barrett's oesophagus
0.962 0.038 0.000
Chapter XX External causes of morbidity and mortality
0.962 0.038 0.000
G30-G32 Other degenerative diseases of the nervous system
0.958 0.042 0.000
Chapter XXII Codes for special purposes
0.953 0.047 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.947 0.053 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.945 0.055 0.000
K50-K52 Noninfective enteritis and colitis
0.943 0.057 0.000
K72 Hepatic failure, not elsewhere classified
0.939 0.061 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.938 0.062 0.000
K50 Crohn's disease [regional enteritis]
0.936 0.064 0.000
G30 Alzheimer's disease
0.934 0.066 0.000
T81 Complications of procedures, not elsewhere classified
0.932 0.068 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.932 0.068 0.000
Chapter X Diseases of the respiratory system
0.932 0.068 0.000
K22.1 Ulcer of oesophagus
0.931 0.069 0.000
F00 Dementia in Alzheimer's disease
0.928 0.072 0.000
K82 Other diseases of gallbladder
0.926 0.074 0.000
D60-D64 Aplastic and other anaemias
0.924 0.076 0.000
D68.2 Hereditary deficiency of other clotting factors
0.923 0.077 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.923 0.077 0.000
K70.3 Alcoholic cirrhosis of liver
0.919 0.081 0.000
K50.1 Crohn's disease of large intestine
0.919 0.081 0.000
F03 Unspecified dementia
0.911 0.089 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.908 0.092 0.000
G30.9 Alzheimer's disease, unspecified
0.907 0.093 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.902 0.098 0.000
K65-K67 Diseases of peritoneum
0.900 0.100 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.892 0.108 0.000
W00-W19 Falls
0.888 0.112 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.882 0.118 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.877 0.123 0.000
K50.9 Crohn's disease, unspecified
0.876 0.124 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.872 0.128 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.871 0.129 0.000
Chapter VIII Diseases of the ear and mastoid process
0.867 0.133 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.863 0.137 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.863 0.137 0.000
D68.0 Von Willebrand's disease
0.861 0.139 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.860 0.140 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.860 0.140 0.000
K70.9 Alcoholic liver disease, unspecified
0.858 0.142 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.857 0.143 0.000
K72.9 Hepatic failure, unspecified
0.852 0.148 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.850 0.150 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.846 0.154 0.000
D61 Other aplastic anaemias
0.846 0.154 0.000
T79-T79 Certain early complications of trauma
0.845 0.155 0.000
K82.8 Other specified diseases of gallbladder
0.843 0.157 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.841 0.159 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.841 0.159 0.000
K22.2 Oesophageal obstruction
0.839 0.161 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.839 0.161 0.000
U80 Agent resistant to penicillin and related antibiotics
0.837 0.163 0.000
T00-T07 Injuries involving multiple body regions
0.835 0.165 0.000
T23 Burn and corrosion of wrist and hand
0.834 0.166 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.834 0.166 0.000
S50-S59 Injuries to the elbow and forearm
0.833 0.167 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.825 0.175 0.000
S10-S19 Injuries to the neck
0.824 0.176 0.000
K82.4 Cholesterolosis of gallbladder
0.822 0.178 0.000
K86 Other diseases of pancreas
0.820 0.180 0.000
W19 Unspecified fall
0.818 0.182 0.000
T81.9 Unspecified complication of procedure
0.818 0.182 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.818 0.182 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.817 0.183 0.000
K72.0 Acute and subacute hepatic failure
0.815 0.185 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.811 0.189 0.000
J30-J39 Other diseases of upper respiratory tract
0.808 0.192 0.000
T86 Failure and rejection of transplanted organs and tissues
0.806 0.194 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.805 0.195 0.000
K70.4 Alcoholic hepatic failure
0.800 0.200 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.800 0.200 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.799 0.201 0.000
K65 Peritonitis
0.798 0.202 0.000
K76 Other diseases of liver
0.796 0.204 0.000
H90-H95 Other disorders of ear
0.796 0.204 0.000
J84 Other interstitial pulmonary diseases
0.795 0.205 0.000
J40-J47 Chronic lower respiratory diseases
0.793 0.207 0.000
D68.5 Primary Thrombophilia
0.790 0.209 0.000
D61.9 Aplastic anaemia, unspecified
0.790 0.210 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.790 0.210 0.000
F80-F89 Disorders of psychological development
0.788 0.212 0.000
K22.8 Other specified diseases of oesophagus
0.785 0.215 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.785 0.215 0.000
D62 Acute posthaemorrhagic anaemia
0.784 0.216 0.000
D75 Other diseases of blood and blood-forming organs
0.782 0.218 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.782 0.218 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.781 0.218 0.000
U80.0 Penicillin resistant agent
0.781 0.219 0.000
V40-V49 Car occupant injured in transport accident
0.780 0.220 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.779 0.221 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.778 0.222 0.000
D68.9 Coagulation defect, unspecified
0.769 0.231 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.768 0.232 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.768 0.232 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.766 0.233 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.766 0.234 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.765 0.235 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.765 0.235 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.764 0.236 0.000
T31 Burns classified according to extent of body surface involved
0.762 0.238 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.762 0.238 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.760 0.239 0.000
D68.8 Other specified coagulation defects
0.760 0.240 0.000
X10-X19 Contact with heat and hot substances
0.759 0.240 0.000
J32 Chronic sinusitis
0.759 0.241 0.000
K70.0 Alcoholic fatty liver
0.759 0.241 0.000
K74 Fibrosis and cirrhosis of liver
0.759 0.241 0.000
K70.1 Alcoholic hepatitis
0.758 0.242 0.000
E70-E90 Metabolic disorders
0.758 0.242 0.000
S20-S29 Injuries to the thorax
0.758 0.242 0.000
G30.0 Alzheimer's disease with early onset
0.757 0.243 0.000
M20-M25 Other joint disorders
0.757 0.243 0.000
J09-J18 Influenza and pneumonia
0.754 0.246 0.000
E86 Volume depletion
0.753 0.247 0.000
K65.9 Peritonitis, unspecified
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.751 0.249 0.000
E20-E35 Disorders of other endocrine glands
0.750 0.250 0.000
W19.2 School, other institution and public administrative area
0.747 0.253 0.000
F99-F99 Unspecified mental disorder
0.745 0.255 0.000
K82.2 Perforation of gallbladder
0.744 0.256 0.000
D73 Diseases of spleen
0.744 0.256 0.000
J47 Bronchiectasis
0.743 0.257 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.743 0.257 0.000
S51 Open wound of forearm
0.743 0.257 0.000
K86.3 Pseudocyst of pancreas
0.742 0.258 0.000
F43 Reaction to severe stress, and adjustment disorders
0.742 0.258 0.000
W11 Fall on and from ladder
0.740 0.260 0.000
L82 Seborrhoeic keratosis
0.740 0.260 0.000
K50.8 Other Crohn's disease
0.740 0.260 0.000
K85 Acute pancreatitis
0.739 0.261 0.000
Y57 Other and unspecified drugs and medicaments
0.737 0.263 0.000
W19.4 Street and highway
0.737 0.263 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.736 0.264 0.000
H90 Conductive and sensorineural hearing loss
0.735 0.265 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.734 0.266 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.734 0.266 0.000
T20 Burn and corrosion of head and neck
0.733 0.267 0.000
F02 Dementia in other diseases classified elsewhere
0.733 0.267 0.000
G62 Other polyneuropathies
0.730 0.270 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.728 0.272 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.726 0.274 0.000
K83 Other diseases of biliary tract
0.726 0.274 0.000
F05.1 Delirium superimposed on dementia
0.725 0.275 0.000
T00 Superficial injuries involving multiple body regions
0.725 0.275 0.000
K66 Other disorders of peritoneum
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.724 0.276 0.000
S40-S49 Injuries to the shoulder and upper arm
0.723 0.277 0.000
X50-X57 Overexertion, travel and privation
0.723 0.277 0.000
J20-J22 Other acute lower respiratory infections
0.723 0.277 0.000
M21 Other acquired deformities of limbs
0.722 0.278 0.000
K80.8 Other cholelithiasis
0.722 0.278 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.722 0.278 0.000
F01 Vascular dementia
0.722 0.278 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.721 0.279 0.000
G31.2 Degeneration of nervous system due to alcohol
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.285 0.000
F70-F79 Mental retardation
0.714 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.713 0.286 0.000
K71 Toxic liver disease
0.713 0.286 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.712 0.288 0.000
F43.2 Adjustment disorders
0.711 0.289 0.000
F22 Persistent delusional disorders
0.710 0.290 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.710 0.290 0.000
Q00-Q07 Congenital malformations of the nervous system
0.710 0.290 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.710 0.290 0.000
F09 Unspecified organic or symptomatic mental disorder
0.710 0.290 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.709 0.290 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
S30.0 Contusion of lower back and pelvis
0.709 0.291 0.000
D55-D59 Haemolytic anaemias
0.708 0.292 0.000
J35 Chronic diseases of tonsils and adenoids
0.706 0.294 0.000
G03 Meningitis due to other and unspecified causes
0.705 0.295 0.000
D67 Hereditary factor IX deficiency
0.703 0.297 0.000
D66 Hereditary factor VIII deficiency
0.703 0.297 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.702 0.297 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.702 0.298 0.000
K73 Chronic hepatitis, not elsewhere classified
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.300 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.699 0.301 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.697 0.303 0.000
D68.6 Other Thrombophilia
0.696 0.304 0.000
D68.4 Acquired coagulation factor deficiency
0.696 0.304 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.696 0.304 0.000
D68.1 Hereditary factor XI deficiency
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.304 0.000
D80-D89 Certain disorders involving the immune mechanism
0.695 0.305 0.000
T31.0 Burns involving less than 10% of body surface
0.695 0.305 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.694 0.306 0.000
M25 Other joint disorders, not elsewhere classified
0.693 0.307 0.000
U88 Agent resistant to multiple antibiotics
0.693 0.307 0.000
S32 Fracture of lumbar spine and pelvis
0.693 0.307 0.000
S31 Open wound of abdomen, lower back and pelvis
0.692 0.308 0.000
F52.2 Failure of genital response
0.691 0.309 0.000
K80.3 Calculus of bile duct with cholangitis
0.691 0.309 0.000
K22.3 Perforation of oesophagus
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.690 0.310 0.000
Y10-Y34 Event of undetermined intent
0.690 0.310 0.000
X85-X99 Assault
0.690 0.310 0.000
X30-X39 Exposure to forces of nature
0.690 0.310 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.310 0.000
X00-X09 Exposure to smoke, fire and flames
0.690 0.310 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.690 0.310 0.000
W75-W84 Other accidental threats to breathing
0.690 0.310 0.000
W65-W74 Accidental drowning and submersion
0.690 0.310 0.000
V98-V99 Other and unspecified transport accidents
0.690 0.310 0.000
V95-V97 Air and space transport accidents
0.690 0.310 0.000
V90-V94 Water transport accidents
0.690 0.310 0.000
V70-V79 Bus occupant injured in transport accident
0.690 0.310 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.690 0.310 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.690 0.310 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.690 0.310 0.000
V01-V09 Pedestrian injured in transport accident
0.690 0.310 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.689 0.311 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.688 0.312 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.687 0.313 0.000
L81 Other disorders of pigmentation
0.687 0.313 0.000
K76.9 Liver disease, unspecified
0.687 0.313 0.000
Y45.0 Opioids and related analgesics
0.685 0.315 0.000
S60-S69 Injuries to the wrist and hand
0.684 0.316 0.000
W18 Other fall on same level
0.684 0.316 0.000
F60-F69 Disorders of adult personality and behaviour
0.683 0.317 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.682 0.318 0.000
S37 Injury of urinary and pelvic organs
0.682 0.318 0.000
L85 Other epidermal thickening
0.681 0.319 0.000
K22.4 Dyskinesia of oesophagus
0.681 0.319 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.681 0.319 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.680 0.320 0.000
T87 Complications peculiar to reattachment and amputation
0.679 0.321 0.000
K28 Gastrojejunal ulcer
0.678 0.322 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.678 0.322 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.678 0.322 0.000
J32.4 Chronic pansinusitis
0.677 0.323 0.000
Y00-Y09 Assault
0.677 0.323 0.000
K22.5 Diverticulum of oesophagus, acquired
0.676 0.324 0.000
S51.0 Open wound of elbow
0.676 0.324 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.675 0.325 0.000
F22.0 Delusional disorder
0.674 0.326 0.000
F05.0 Delirium not superimposed on dementia, so described
0.674 0.326 0.000
K72.1 Chronic hepatic failure
0.673 0.327 0.000
T25 Burn and corrosion of ankle and foot
0.673 0.327 0.000
T21 Burn and corrosion of trunk
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.673 0.327 0.000
V10-V19 Pedal cyclist injured in transport accident
0.672 0.328 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.672 0.328 0.000
F06.7 Mild cognitive disorder
0.672 0.328 0.000
G60 Hereditary and idiopathic neuropathy
0.671 0.329 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.670 0.330 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.670 0.330 0.000
W08 Fall involving other furniture
0.669 0.330 0.000
G30.8 Other Alzheimer's disease
0.669 0.330 0.000
G30.1 Alzheimer's disease with late onset
0.669 0.330 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.669 0.331 0.000
S12 Fracture of neck
0.667 0.333 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.667 0.333 0.000
Y52 Agents primarily affecting the cardiovascular system
0.667 0.333 0.000
F11 Mental and behavioural disorders due to use of opioids
0.666 0.334 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.666 0.334 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.666 0.334 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.665 0.335 0.000
K82.3 Fistula of gallbladder
0.664 0.336 0.000
K82.0 Obstruction of gallbladder
0.664 0.336 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.664 0.336 0.000
U89 Agent resistant to other and unspecified antibiotics
0.664 0.336 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.662 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.662 0.338 0.000
S36 Injury of intra-abdominal organs
0.662 0.338 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.662 0.338 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.662 0.338 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.662 0.338 0.000
Y40 Systemic antibiotics
0.661 0.339 0.000
L20-L30 Dermatitis and eczema
0.661 0.339 0.000
H93 Other disorders of ear, not elsewhere classified
0.660 0.339 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.660 0.340 0.000
J32.9 Chronic sinusitis, unspecified
0.659 0.341 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.659 0.341 0.000
J46 Status asthmaticus
0.659 0.341 0.000
T82.3 Mechanical complication of other vascular grafts
0.659 0.341 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.659 0.341 0.000
J90-J94 Other diseases of pleura
0.659 0.341 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.658 0.342 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.658 0.342 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.658 0.342 0.000
U80.1 Methicillin resistant agent
0.657 0.343 0.000
J30 Vasomotor and allergic rhinitis
0.656 0.344 0.000
J33 Nasal polyp
0.656 0.344 0.000
S59 Other and unspecified injuries of forearm
0.655 0.345 0.000
T82.1 Mechanical complication of cardiac electronic device
0.654 0.346 0.000
S19 Other and unspecified injuries of neck
0.654 0.346 0.000
H80-H83 Diseases of inner ear
0.654 0.346 0.000
W10 Fall on and from stairs and steps
0.653 0.347 0.000
L80 Vitiligo
0.652 0.348 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.652 0.348 0.000
Q76 Congenital malformations of spine and bony thorax
0.652 0.348 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.651 0.349 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.651 0.349 0.000
W06 Fall involving bed
0.650 0.349 0.000
M21.3 Wrist or foot drop (acquired)
0.650 0.350 0.000
F80 Specific developmental disorders of speech and language
0.650 0.350 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.649 0.351 0.000
K86.8 Other specified diseases of pancreas
0.649 0.351 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.649 0.351 0.000
J40 Bronchitis, not specified as acute or chronic
0.648 0.352 0.000
M60-M63 Disorders of muscles
0.648 0.352 0.000
D75.1 Secondary polycythaemia
0.646 0.353 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.646 0.354 0.000
S20 Superficial injury of thorax
0.646 0.354 0.000
W20-W49 Exposure to inanimate mechanical forces
0.645 0.355 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.644 0.356 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.642 0.358 0.000
T23.3 Burn of third degree of wrist and hand
0.642 0.358 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.641 0.359 0.000
T23.2 Burn of second degree of wrist and hand
0.641 0.359 0.000
S50 Superficial injury of forearm
0.641 0.359 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.640 0.360 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.639 0.361 0.000
Q35-Q37 Cleft lip and cleft palate
0.639 0.361 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.639 0.361 0.000
F05.9 Delirium, unspecified
0.639 0.361 0.000
G12 Spinal muscular atrophy and related syndromes
0.638 0.362 0.000
G00 Bacterial meningitis, not elsewhere classified
0.638 0.362 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.638 0.362 0.000
Q65 Congenital deformities of hip
0.637 0.363 0.000
Q79.6 Ehlers-Danlos syndrome
0.637 0.363 0.000
K74.3 Primary biliary cirrhosis
0.637 0.363 0.000
W17 Other fall from one level to another
0.637 0.363 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.637 0.363 0.000
W15 Fall from cliff
0.637 0.363 0.000
W14 Fall from tree
0.637 0.363 0.000
W12 Fall on and from scaffolding
0.637 0.363 0.000
W09 Fall involving playground equipment
0.637 0.363 0.000
W05 Fall involving wheelchair
0.637 0.363 0.000
W04 Fall while being carried or supported by other persons
0.637 0.363 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.637 0.363 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.637 0.363 0.000
W00 Fall on same level involving ice and snow
0.637 0.363 0.000
D63.0 Anaemia in neoplastic disease
0.636 0.364 0.000
W11.6 Industrial and construction area
0.634 0.366 0.000
E23 Hypofunction and other disorders of pituitary gland
0.633 0.367 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.633 0.367 0.000
U50 Level of care administered to neonates
0.632 0.368 0.000
U07 Emergency use of U07
0.632 0.368 0.000
U06 Emergency use of U06
0.632 0.368 0.000
U04 Severe acute respiratory syndrome [SARS]
0.632 0.368 0.000
U52 First in a series of a regular day/night admissions
0.632 0.368 0.000
L81.4 Other melanin hyperpigmentation
0.632 0.368 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.631 0.369 0.000
M35 Other systemic involvement of connective tissue
0.631 0.369 0.000
M33 Dermatopolymyositis
0.630 0.370 0.000
Y48 Anaesthetics and therapeutic gases
0.628 0.371 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.628 0.371 0.000
D73.8 Other diseases of spleen
0.628 0.372 0.000
T86.1 Kidney transplant failure and rejection
0.628 0.372 0.000
F12.1 Harmful use
0.627 0.373 0.000
D69 Purpura and other haemorrhagic conditions
0.627 0.373 0.000
Y45.2 Propionic acid derivatives
0.626 0.373 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.625 0.375 0.000
Y59 Other and unspecified vaccines and biological substances
0.625 0.375 0.000
Y58 Bacterial vaccines
0.625 0.375 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.625 0.375 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.625 0.375 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.625 0.375 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.625 0.375 0.000
S70-S79 Injuries to the hip and thigh
0.625 0.375 0.000
L40-L45 Papulosquamous disorders
0.625 0.375 0.000
J35.1 Hypertrophy of tonsils
0.624 0.376 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.624 0.376 0.000
L60-L75 Disorders of skin appendages
0.624 0.376 0.000
S56 Injury of muscle and tendon at forearm level
0.623 0.377 0.000
Y95 Nosocomial condition
0.623 0.377 0.000
E34 Other endocrine disorders
0.620 0.380 0.000
M34 Systemic sclerosis
0.619 0.381 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.619 0.381 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.619 0.381 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.619 0.381 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.619 0.381 0.000
G64 Other disorders of peripheral nervous system
0.618 0.381 0.000
E40-E46 Malnutrition
0.618 0.382 0.000
Y43 Primarily systemic agents
0.617 0.383 0.000
F05.8 Other delirium
0.616 0.384 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.616 0.384 0.000
F51 Nonorganic sleep disorders
0.616 0.384 0.000
F50 Eating disorders
0.616 0.384 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.616 0.384 0.000
F55 Abuse of non-dependence-producing substances
0.616 0.384 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.616 0.384 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.616 0.384 0.000
S51.8 Open wound of other parts of forearm
0.616 0.384 0.000
L85.8 Other specified epidermal thickening
0.615 0.385 0.000
G71 Primary disorders of muscles
0.615 0.385 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.614 0.385 0.000
T32 Corrosions classified according to extent of body surface involved
0.614 0.386 0.000
T30 Burn and corrosion, body region unspecified
0.614 0.386 0.000
T29 Burns and corrosions of multiple body regions
0.614 0.386 0.000
H90.2 Conductive hearing loss, unspecified
0.611 0.389 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.611 0.389 0.000
Q50-Q56 Congenital malformations of genital organs
0.610 0.389 0.000
K66.0 Peritoneal adhesions
0.610 0.390 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.610 0.390 0.000
J18 Pneumonia, organism unspecified
0.610 0.390 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.610 0.390 0.000
D74 Methaemoglobinaemia
0.610 0.390 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.610 0.390 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.610 0.390 0.000
S60 Superficial injury of wrist and hand
0.609 0.390 0.000
H65-H75 Diseases of middle ear and mastoid
0.608 0.392 0.000
K82.9 Disease of gallbladder, unspecified
0.608 0.392 0.000
T86.0 Bone-marrow transplant rejection
0.608 0.392 0.000
J92 Pleural plaque
0.608 0.392 0.000
V20-V29 Motorcycle rider injured in transport accident
0.607 0.393 0.000
D61.8 Other specified aplastic anaemias
0.606 0.393 0.000
D61.3 Idiopathic aplastic anaemia
0.606 0.393 0.000
D61.2 Aplastic anaemia due to other external agents
0.606 0.393 0.000
D61.1 Drug-induced aplastic anaemia
0.606 0.393 0.000
D61.0 Constitutional aplastic anaemia
0.606 0.393 0.000
K22.0 Achalasia of cardia
0.606 0.394 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.605 0.395 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.603 0.397 0.000
G31.0 Circumscribed brain atrophy
0.603 0.397 0.000
Y57.5 X-ray contrast media
0.603 0.397 0.000
Q66 Congenital deformities of feet
0.602 0.398 0.000
F48 Other neurotic disorders
0.602 0.398 0.000
T00.9 Multiple superficial injuries, unspecified
0.601 0.399 0.000
E21.0 Primary hyperparathyroidism
0.601 0.399 0.000
G61 Inflammatory polyneuropathy
0.601 0.399 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.600 0.400 0.000
T02 Fractures involving multiple body regions
0.599 0.400 0.000
J60-J70 Lung diseases due to external agents
0.599 0.401 0.000
T06 Other injuries involving multiple body regions, not elsewhere classified
0.599 0.401 0.000
T05 Traumatic amputations involving multiple body regions
0.599 0.401 0.000
T04 Crushing injuries involving multiple body regions
0.599 0.401 0.000
T03 Dislocations, sprains and strains involving multiple body regions
0.599 0.401 0.000
T01 Open wounds involving multiple body regions
0.599 0.401 0.000
T07 Unspecified multiple injuries
0.599 0.401 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.598 0.402 0.000
K76.8 Other specified diseases of liver
0.598 0.402 0.000
X45 Accidental poisoning by and exposure to alcohol
0.598 0.402 0.000
M86-M90 Other osteopathies
0.598 0.402 0.000
T23.7 Corrosion of third degree of wrist and hand
0.598 0.402 0.000
T23.6 Corrosion of second degree of wrist and hand
0.598 0.402 0.000
T23.5 Corrosion of first degree of wrist and hand
0.598 0.402 0.000
T23.4 Corrosion of unspecified degree of wrist and hand
0.598 0.402 0.000
T23.1 Burn of first degree of wrist and hand
0.598 0.402 0.000
L10-L14 Bullous disorders
0.598 0.402 0.000
D72 Other disorders of white blood cells
0.598 0.402 0.000
S58 Traumatic amputation of forearm
0.597 0.403 0.000
S57 Crushing injury of forearm
0.597 0.403 0.000
S55 Injury of blood vessels at forearm level
0.597 0.403 0.000
S54 Injury of nerves at forearm level
0.597 0.403 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.597 0.403 0.000
J37 Chronic laryngitis and laryngotracheitis
0.597 0.403 0.000
J32.8 Other chronic sinusitis
0.596 0.404 0.000
K83.1 Obstruction of bile duct
0.595 0.405 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.595 0.405 0.000
J95-J99 Other diseases of the respiratory system
0.595 0.405 0.000
Y57.8 Other drugs and medicaments
0.595 0.405 0.000
L84 Corns and callosities
0.595 0.405 0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)
0.593 0.407 0.000
L83 Acanthosis nigricans
0.593 0.407 0.000
G83 Other paralytic syndromes
0.593 0.407 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.592 0.408 0.000
G62.0 Drug-induced polyneuropathy
0.592 0.408 0.000
U84 Resistance to other antimicrobial drugs
0.592 0.408 0.000
U83 Resistance to other antibiotics
0.592 0.408 0.000
U82 Resistance to betalactam antibiotics
0.592 0.408 0.000
U85 Resistance to antineoplastic drugs
0.592 0.408 0.000
M24 Other specific joint derangements
0.592 0.408 0.000
M80-M85 Disorders of bone density and structure
0.591 0.409 0.000
G03.9 Meningitis, unspecified
0.591 0.409 0.000
S17 Crushing injury of neck
0.591 0.409 0.000
S15 Injury of blood vessels at neck level
0.591 0.409 0.000
S14 Injury of nerves and spinal cord at neck level
0.591 0.409 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.591 0.409 0.000
S11 Open wound of neck
0.591 0.409 0.000
S18 Traumatic amputation at neck level
0.591 0.409 0.000
S16 Injury of muscle and tendon at neck level
0.591 0.409 0.000
J10 Influenza due to identified influenza virus
0.590 0.410 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.590 0.410 0.000
X60-X84 Intentional self-harm
0.590 0.410 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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