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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs66723041
log Bayes Factor = 214.427
Chromosome 6   position 32,520,707  (GRCh37) Explore rs66723041 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.001 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.002 0.998
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
K82 Other diseases of gallbladder
0.000 0.006 0.994
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
H43-H45 Disorders of vitreous body and globe
0.000 0.009 0.991
K82.8 Other specified diseases of gallbladder
0.000 0.010 0.990
E78.0 Pure hypercholesterolaemia
0.000 0.012 0.988
K50-K52 Noninfective enteritis and colitis
0.003 0.013 0.984
H43 Disorders of vitreous body
0.000 0.013 0.987
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.013 0.987
K70-K77 Diseases of liver
0.000 0.013 0.987
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.013 0.987
E10.5 With peripheral circulatory complications
0.000 0.017 0.983
J33.9 Nasal polyp, unspecified
0.000 0.017 0.983
J33 Nasal polyp
0.000 0.020 0.980
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.021 0.979
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.021 0.979
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.022 0.978
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.023 0.977
E70-E90 Metabolic disorders
0.000 0.026 0.974
E11.1 With ketoacidosis
0.000 0.029 0.971
E11.3 With ophthalmic complications
0.000 0.031 0.969
K51.8 Other ulcerative colitis
0.969 0.031 0.000
K55-K64 Other diseases of intestines
0.000 0.037 0.963
M06.0 Seronegative rheumatoid arthritis
0.000 0.040 0.960
H43.3 Other vitreous opacities
0.000 0.041 0.959
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.042 0.958
K74 Fibrosis and cirrhosis of liver
0.000 0.043 0.957
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.045 0.955
K50 Crohn's disease [regional enteritis]
0.000 0.046 0.954
H43.8 Other disorders of vitreous body
0.000 0.048 0.952
J30-J39 Other diseases of upper respiratory tract
0.000 0.051 0.949
J33.8 Other polyp of sinus
0.000 0.052 0.948
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.055 0.945
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.057 0.943
J46 Status asthmaticus
0.000 0.058 0.942
E05.9 Thyrotoxicosis, unspecified
0.000 0.059 0.941
E10.2 With renal complications
0.000 0.059 0.941
K60 Fissure and fistula of anal and rectal regions
0.000 0.061 0.939
J43 Emphysema
0.000 0.061 0.939
E06 Thyroiditis
0.000 0.064 0.936
K58 Irritable bowel syndrome
0.000 0.068 0.932
K75 Other inflammatory liver diseases
0.000 0.073 0.927
E11.5 With peripheral circulatory complications
0.000 0.076 0.924
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.077 0.923
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.082 0.918
K74.3 Primary biliary cirrhosis
0.000 0.083 0.917
L40-L45 Papulosquamous disorders
0.000 0.088 0.912
L43.9 Lichen planus, unspecified
0.000 0.088 0.912
L43 Lichen planus
0.000 0.088 0.912
K72 Hepatic failure, not elsewhere classified
0.000 0.088 0.912
J86 Pyothorax
0.000 0.089 0.911
H34 Retinal vascular occlusions
0.000 0.090 0.910
H40-H42 Glaucoma
0.000 0.092 0.908
K63 Other diseases of intestine
0.000 0.093 0.907
M07 Psoriatic and enteropathic arthropathies
0.000 0.095 0.905
K52 Other non-infective gastro-enteritis and colitis
0.001 0.097 0.902
K82.1 Hydrops of gallbladder
0.000 0.098 0.902
E03.8 Other specified hypothyroidism
0.000 0.099 0.901
K75.4 Autoimmune hepatitis
0.000 0.100 0.900
L40 Psoriasis
0.000 0.100 0.900
M65-M68 Disorders of synovium and tendon
0.000 0.103 0.897
K81 Cholecystitis
0.000 0.103 0.897
K86 Other diseases of pancreas
0.000 0.107 0.893
E11.6 With other specified complications
0.000 0.107 0.893
E06.3 Autoimmune thyroiditis
0.000 0.107 0.893
K60.2 Anal fissure, unspecified
0.000 0.108 0.892
L40.5 Arthropathic psoriasis
0.000 0.108 0.892
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.112 0.888
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.112 0.888
K63.9 Disease of intestine, unspecified
0.000 0.114 0.886
E11.2 With renal complications
0.000 0.115 0.885
K60.0 Acute anal fissure
0.000 0.115 0.885
E07 Other disorders of thyroid
0.000 0.118 0.882
J43.9 Emphysema, unspecified
0.000 0.119 0.881
K51.2 Ulcerative (chronic) proctitis
0.878 0.122 0.000
M06.3 Rheumatoid nodule
0.000 0.133 0.867
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.133 0.867
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.134 0.866
K50.1 Crohn's disease of large intestine
0.000 0.140 0.860
Chapter IX Diseases of the circulatory system
0.000 0.140 0.860
K50.8 Other Crohn's disease
0.000 0.144 0.856
K81.1 Chronic cholecystitis
0.000 0.144 0.856
I10-I15 Hypertensive diseases
0.000 0.144 0.856
J86.9 Pyothorax without fistula
0.000 0.146 0.854
M65 Synovitis and tenosynovitis
0.000 0.149 0.851
E13 Other specified diabetes mellitus
0.000 0.152 0.848
H40 Glaucoma
0.000 0.157 0.843
I20-I25 Ischaemic heart diseases
0.000 0.158 0.842
M07.3 Other psoriatic arthropathies
0.000 0.163 0.837
K51.5 Mucosal proctocolitis
0.836 0.164 0.000
K63.3 Ulcer of intestine
0.000 0.164 0.836
H40.9 Glaucoma, unspecified
0.000 0.168 0.832
I10 Essential (primary) hypertension
0.000 0.169 0.831
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.831 0.169 0.000
H25-H28 Disorders of lens
0.000 0.170 0.830
K86.2 Cyst of pancreas
0.000 0.171 0.829
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.176 0.824
K52.1 Toxic gastro-enteritis and colitis
0.000 0.176 0.824
M06.4 Inflammatory polyarthropathy
0.000 0.177 0.823
K74.5 Biliary cirrhosis, unspecified
0.000 0.178 0.822
J33.0 Polyp of nasal cavity
0.000 0.178 0.822
K60.5 Anorectal fistula
0.000 0.179 0.821
G37.8 Other specified demyelinating diseases of central nervous system
0.820 0.180 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.185 0.815
K50.0 Crohn's disease of small intestine
0.000 0.185 0.815
I22 Subsequent myocardial infarction
0.000 0.185 0.815
M14 Arthropathies in other diseases classified elsewhere
0.000 0.186 0.814
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.186 0.814
E07.9 Disorder of thyroid, unspecified
0.000 0.187 0.813
J86.0 Pyothorax with fistula
0.000 0.191 0.809
K51.4 Pseudopolyposis of colon
0.809 0.191 0.000
K72.9 Hepatic failure, unspecified
0.000 0.200 0.800
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.201 0.799
E16.1 Other hypoglycaemia
0.000 0.202 0.798
H34.8 Other retinal vascular occlusions
0.000 0.204 0.796
K73 Chronic hepatitis, not elsewhere classified
0.000 0.205 0.795
E40-E46 Malnutrition
0.000 0.206 0.794
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.209 0.791
I20 Angina pectoris
0.000 0.211 0.789
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.213 0.787
K72.0 Acute and subacute hepatic failure
0.000 0.213 0.787
I12 Hypertensive renal disease
0.000 0.216 0.784
E78.2 Mixed hyperlipidaemia
0.000 0.217 0.783
H27 Other disorders of lens
0.000 0.219 0.781
E78.1 Pure hyperglyceridaemia
0.000 0.220 0.780
K55 Vascular disorders of intestine
0.000 0.220 0.780
K90.9 Intestinal malabsorption, unspecified
0.000 0.226 0.774
K82.9 Disease of gallbladder, unspecified
0.000 0.226 0.774
K63.4 Enteroptosis
0.000 0.226 0.774
K81.9 Cholecystitis, unspecified
0.000 0.228 0.772
K80 Cholelithiasis
0.000 0.228 0.772
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.229 0.771
J95-J99 Other diseases of the respiratory system
0.000 0.237 0.763
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.238 0.762
E11.0 With coma
0.000 0.239 0.760
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.242 0.758
E78.5 Hyperlipidaemia, unspecified
0.000 0.245 0.755
E88 Other metabolic disorders
0.000 0.247 0.753
H43.9 Disorder of vitreous body, unspecified
0.000 0.247 0.753
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.251 0.749
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.253 0.747
J37 Chronic laryngitis and laryngotracheitis
0.000 0.254 0.745
E83 Disorders of mineral metabolism
0.640 0.255 0.105
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.255 0.744
K82.3 Fistula of gallbladder
0.000 0.257 0.743
M06.34 Rheumatoid nodule (Hand)
0.000 0.260 0.740
E13.9 Without complications
0.000 0.261 0.739
K86.3 Pseudocyst of pancreas
0.000 0.262 0.738
E11.4 With neurological complications
0.000 0.263 0.737
K74.6 Other and unspecified cirrhosis of liver
0.000 0.263 0.737
I20.1 Angina pectoris with documented spasm
0.000 0.265 0.735
J43.2 Centrilobular emphysema
0.000 0.265 0.735
K82.2 Perforation of gallbladder
0.000 0.266 0.734
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.267 0.733
H43.2 Crystalline deposits in vitreous body
0.000 0.268 0.732
M11 Other crystal arthropathies
0.000 0.268 0.732
H34.2 Other retinal artery occlusions
0.000 0.271 0.729
H34.1 Central retinal artery occlusion
0.000 0.271 0.729
K75.9 Inflammatory liver disease, unspecified
0.000 0.272 0.728
I15 Secondary hypertension
0.000 0.272 0.728
I24 Other acute ischaemic heart diseases
0.000 0.273 0.727
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.274 0.726
M14.6 Neuropathic arthropathy
0.000 0.274 0.726
K62 Other diseases of anus and rectum
0.000 0.275 0.725
K63.2 Fistula of intestine
0.000 0.275 0.725
K86.1 Other chronic pancreatitis
0.000 0.275 0.725
L43.8 Other lichen planus
0.000 0.276 0.724
H30 Chorioretinal inflammation
0.000 0.276 0.723
H40.1 Primary open-angle glaucoma
0.000 0.279 0.721
E74 Other disorders of carbohydrate metabolism
0.000 0.280 0.720
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.285 0.715
H43.1 Vitreous haemorrhage
0.000 0.286 0.714
M70-M79 Other soft tissue disorders
0.000 0.287 0.713
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.289 0.710
H43.0 Vitreous prolapse
0.000 0.292 0.708
K77 Liver disorders in diseases classified elsewhere
0.000 0.292 0.708
K71 Toxic liver disease
0.000 0.292 0.708
K51.0 Ulcerative (chronic) enterocolitis
0.706 0.293 0.000
J42 Unspecified chronic bronchitis
0.000 0.296 0.704
E11.8 With unspecified complications
0.000 0.297 0.703
J33.1 Polypoid sinus degeneration
0.000 0.297 0.703
J41 Simple and mucopurulent chronic bronchitis
0.000 0.298 0.702
E78.6 Lipoprotein deficiency
0.000 0.298 0.701
E78.3 Hyperchylomicronaemia
0.000 0.298 0.701
L40.9 Psoriasis, unspecified
0.000 0.300 0.700
I12.9 Hypertensive renal disease without renal failure
0.000 0.301 0.699
E77 Disorders of glycoprotein metabolism
0.000 0.301 0.698
E76 Disorders of glycosaminoglycan metabolism
0.000 0.301 0.698
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.301 0.698
E72 Other disorders of amino-acid metabolism
0.000 0.301 0.698
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.301 0.698
E70 Disorders of aromatic amino-acid metabolism
0.000 0.301 0.698
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.301 0.698
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.302 0.698
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.303 0.697
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.305 0.695
H27.0 Aphakia
0.000 0.307 0.693
K62.4 Stenosis of anus and rectum
0.000 0.309 0.691
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.309 0.691
I20.9 Angina pectoris, unspecified
0.000 0.310 0.690
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.311 0.689
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.311 0.689
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.311 0.689
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.311 0.689
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.311 0.689
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.311 0.689
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.311 0.689
E05.5 Thyroid crisis or storm
0.000 0.313 0.687
E05.4 Thyrotoxicosis factitia
0.000 0.313 0.687
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.313 0.687
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.313 0.687
K82.0 Obstruction of gallbladder
0.000 0.313 0.686
K74.4 Secondary biliary cirrhosis
0.000 0.314 0.686
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.314 0.686
K74.1 Hepatic sclerosis
0.000 0.314 0.686
H40.5 Glaucoma secondary to other eye disorders
0.000 0.314 0.686
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.317 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.318 0.682
I20.0 Unstable angina
0.000 0.320 0.680
M66 Spontaneous rupture of synovium and tendon
0.000 0.324 0.676
J43.8 Other emphysema
0.000 0.327 0.673
J43.1 Panlobular emphysema
0.000 0.327 0.673
J43.0 MacLeod's syndrome
0.000 0.327 0.673
K62.1 Rectal polyp
0.000 0.328 0.672
H27.8 Other specified disorders of lens
0.000 0.328 0.672
K55.8 Other vascular disorders of intestine
0.000 0.329 0.671
E06.5 Other chronic thyroiditis
0.000 0.329 0.671
E06.4 Drug-induced thyroiditis
0.000 0.329 0.671
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.329 0.671
E06.1 Subacute thyroiditis
0.000 0.329 0.671
E06.0 Acute thyroiditis
0.000 0.329 0.671
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.331 0.669
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.333 0.667
M12 Other specific arthropathies
0.000 0.333 0.666
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.335 0.665
K80.8 Other cholelithiasis
0.000 0.335 0.665
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.335 0.665
K75.2 Nonspecific reactive hepatitis
0.000 0.335 0.665
K75.1 Phlebitis of portal vein
0.000 0.335 0.665
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.337 0.662
M77 Other enthesopathies
0.000 0.342 0.658
K55.2 Angiodysplasia of colon
0.000 0.344 0.656
E84 Cystic fibrosis
0.000 0.345 0.655
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.345 0.655
L44 Other papulosquamous disorders
0.000 0.346 0.654
L41 Parapsoriasis
0.000 0.346 0.654
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.346 0.654
L43.3 Subacute (active) lichen planus
0.000 0.346 0.654
L43.2 Lichenoid drug reaction
0.000 0.346 0.654
L43.1 Bullous lichen planus
0.000 0.346 0.654
L43.0 Hypertrophic lichen planus
0.000 0.346 0.654
K72.1 Chronic hepatic failure
0.000 0.346 0.654
J98 Other respiratory disorders
0.000 0.347 0.653
H34.0 Transient retinal artery occlusion
0.000 0.348 0.652
I12.0 Hypertensive renal disease with renal failure
0.000 0.348 0.652
H42 Glaucoma in diseases classified elsewhere
0.000 0.349 0.651
E06.9 Thyroiditis, unspecified
0.000 0.349 0.651
L40.8 Other psoriasis
0.000 0.350 0.650
M77.1 Lateral epicondylitis
0.000 0.350 0.650
M07.6 Other enteropathic arthropathies
0.000 0.351 0.649
M07.5 Arthropathy in ulcerative colitis
0.000 0.351 0.649
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.351 0.649
M07.2 Psoriatic spondylitis
0.000 0.351 0.649
M07.1 Arthritis mutilans
0.000 0.351 0.649
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.351 0.649
H25 Senile cataract
0.000 0.353 0.647
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.353 0.647
I23 Certain current complications following acute myocardial infarction
0.000 0.353 0.647
E46 Unspecified protein-energy malnutrition
0.000 0.354 0.646
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.355 0.645
L40.4 Guttate psoriasis
0.000 0.355 0.645
L40.3 Pustulosis palmaris et plantaris
0.000 0.355 0.645
L40.2 Acrodermatitis continua
0.000 0.355 0.645
L40.1 Generalised pustular psoriasis
0.000 0.355 0.645
M65.1 Other infective (teno)synovitis
0.000 0.355 0.645
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.355 0.645
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.357 0.643
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.360 0.640
H25.1 Senile nuclear cataract
0.000 0.361 0.639
M10 Gout
0.000 0.365 0.635
E79 Disorders of purine and pyrimidine metabolism
0.000 0.367 0.633
K75.8 Other specified inflammatory liver diseases
0.000 0.367 0.633
E07.1 Dyshormogenetic goitre
0.000 0.368 0.632
E07.0 Hypersecretion of calcitonin
0.000 0.368 0.632
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.369 0.631
K62.0 Anal polyp
0.000 0.372 0.628
K73.9 Chronic hepatitis, unspecified
0.000 0.372 0.628
J32 Chronic sinusitis
0.000 0.373 0.627
K90.8 Other intestinal malabsorption
0.000 0.375 0.624
J98.4 Other disorders of lung
0.000 0.375 0.625
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.377 0.623
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.378 0.622
M06.38 Rheumatoid nodule (Other)
0.000 0.378 0.622
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.378 0.622
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.378 0.622
M06.33 Rheumatoid nodule (Forearm)
0.000 0.378 0.622
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.378 0.622
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.378 0.622
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.378 0.622
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.379 0.621
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.381 0.619
H34.9 Retinal vascular occlusion, unspecified
0.000 0.381 0.619
E03.1 Congenital hypothyroidism without goitre
0.000 0.382 0.618
I00-I02 Acute rheumatic fever
0.000 0.383 0.617
G56.0 Carpal tunnel syndrome
0.000 0.383 0.617
E05.8 Other thyrotoxicosis
0.000 0.383 0.616
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.384 0.616
M45-M49 Spondylopathies
0.000 0.384 0.616
I13 Hypertensive heart and renal disease
0.000 0.386 0.613
I15.1 Hypertension secondary to other renal disorders
0.000 0.389 0.611
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.389 0.611
K50.9 Crohn's disease, unspecified
0.000 0.390 0.610
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.390 0.610
K91.3 Postoperative intestinal obstruction
0.000 0.390 0.610
M65.2 Calcific tendinitis
0.000 0.390 0.610
M65.0 Abscess of tendon sheath
0.000 0.390 0.610
Chapter VI Diseases of the nervous system
0.009 0.390 0.600
E78.8 Other disorders of lipoprotein metabolism
0.000 0.391 0.609
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.391 0.609
E13.8 With unspecified complications
0.000 0.392 0.608
E13.7 With multiple complications
0.000 0.392 0.608
E13.6 With other specified complications
0.000 0.392 0.608
E13.5 With peripheral circulatory complications
0.000 0.392 0.608
E13.4 With neurological complications
0.000 0.392 0.608
E13.3 With ophthalmic complications
0.000 0.392 0.608
E13.2 With renal complications
0.000 0.392 0.608
E13.1 With ketoacidosis
0.000 0.392 0.608
E13.0 With coma
0.000 0.392 0.608
E73 Lactose intolerance
0.000 0.392 0.607
K86.8 Other specified diseases of pancreas
0.000 0.393 0.607
H40.6 Glaucoma secondary to drugs
0.000 0.396 0.604
H40.4 Glaucoma secondary to eye inflammation
0.000 0.396 0.604
H40.3 Glaucoma secondary to eye trauma
0.000 0.396 0.604
K74.0 Hepatic fibrosis
0.000 0.396 0.604
H27.1 Dislocation of lens
0.000 0.397 0.603
J85 Abscess of lung and mediastinum
0.000 0.397 0.603
G50-G59 Nerve, nerve root and plexus disorders
0.001 0.398 0.601
G56 Mononeuropathies of upper limb
0.000 0.399 0.601
M07.38 Other psoriatic arthropathies (Other)
0.000 0.400 0.600
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.400 0.600
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.400 0.600
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.400 0.600
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.400 0.600
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.400 0.600
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.400 0.600
J37.0 Chronic laryngitis
0.000 0.400 0.600
I11 Hypertensive heart disease
0.000 0.401 0.599
K81.8 Other cholecystitis
0.000 0.401 0.598
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.405 0.595
K60.1 Chronic anal fissure
0.000 0.405 0.595
L10-L14 Bullous disorders
0.000 0.405 0.594
M45 Ankylosing spondylitis
0.000 0.406 0.594
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.410 0.590
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.410 0.590
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.410 0.590
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.410 0.590
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.410 0.590
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.410 0.590
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.410 0.590
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.410 0.590
L42 Pityriasis rosea
0.000 0.412 0.588
H33 Retinal detachments and breaks
0.000 0.413 0.587
E83.9 Disorder of mineral metabolism, unspecified
0.524 0.414 0.061
G59 Mononeuropathy in diseases classified elsewhere
0.001 0.414 0.585
E83.3 Disorders of phosphorus metabolism
0.550 0.415 0.035
K62.7 Radiation proctitis
0.000 0.416 0.584
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.416 0.584
M14.4 Arthropathy in amyloidosis
0.000 0.416 0.584
M14.3 Lipoid dermatoarthritis
0.000 0.416 0.584
M14.2 Diabetic arthropathy
0.000 0.416 0.584
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.416 0.584
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.416 0.584
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.416 0.584
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.416 0.584
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.416 0.584
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.416 0.584
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.416 0.584
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.416 0.584
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.416 0.584
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.416 0.584
K55.1 Chronic vascular disorders of intestine
0.000 0.417 0.583
K91.1 Postgastric surgery syndromes
0.000 0.423 0.577
H44 Disorders of globe
0.000 0.424 0.576
E85 Amyloidosis
0.000 0.424 0.575
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.425 0.575
E07.8 Other specified disorders of thyroid
0.000 0.425 0.574
G59.0 Diabetic mononeuropathy
0.000 0.426 0.574
E88.2 Lipomatosis, not elsewhere classified
0.000 0.428 0.572
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.430 0.570
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.430 0.570
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.430 0.570
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.431 0.569

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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