TreeWAS – Variant ID: rs6684428

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.279	0.721	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.278	0.722	0.000
S60-S69 Injuries to the wrist and hand	0.276	0.724	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.260	0.740	0.000
S62 Fracture at wrist and hand level	0.246	0.754	0.000
S60 Superficial injury of wrist and hand	0.239	0.760	0.000
S64 Injury of nerves at wrist and hand level	0.239	0.761	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.237	0.763	0.000
S62.5 Fracture of thumb	0.237	0.763	0.000
S68 Traumatic amputation of wrist and hand	0.234	0.766	0.000
S62.50 Fracture of thumb (closed)	0.231	0.769	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.231	0.769	0.000
S69 Other and unspecified injuries of wrist and hand	0.230	0.770	0.000
S65 Injury of blood vessels at wrist and hand level	0.227	0.773	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.225	0.775	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.223	0.777	0.000
S63.6 Sprain and strain of finger(s)	0.221	0.779	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.217	0.783	0.000
S60.8 Other superficial injuries of wrist and hand	0.214	0.786	0.000
S64.4 Injury of digital nerve of other finger	0.212	0.788	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.210	0.790	0.000
S63.0 Dislocation of wrist	0.200	0.799	0.000
S62.7 Multiple fractures of fingers	0.200	0.800	0.000
S64.3 Injury of digital nerve of thumb	0.200	0.800	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.199	0.800	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.199	0.800	0.000
S69.7 Multiple injuries of wrist and hand	0.193	0.807	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.192	0.808	0.000
S65.5 Injury of blood vessel(s) of other finger	0.190	0.810	0.000
S62.1 Fracture of other carpal bone(s)	0.188	0.812	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.188	0.812	0.000
S69.9 Unspecified injury of wrist and hand	0.187	0.813	0.000
S60.1 Contusion of finger(s) with damage to nail	0.187	0.813	0.000
S63.1 Dislocation finger	0.186	0.813	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.186	0.813	0.000
S63.2 Multiple dislocations of fingers	0.186	0.813	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.180	0.820	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.176	0.824	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.174	0.826	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.172	0.828	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.171	0.829	0.000
S64.8 Injury of other nerves at wrist and hand level	0.171	0.829	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.171	0.829	0.000
S62.3 Fracture of other metacarpal bone	0.171	0.829	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.171	0.829	0.000
S63.5 Sprain and strain of wrist	0.170	0.829	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.168	0.832	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.168	0.832	0.000
S68.4 Traumatic amputation of hand at wrist level	0.168	0.832	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.168	0.832	0.000
S60.0 Contusion of finger(s) without damage to nail	0.167	0.833	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.166	0.834	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.163	0.837	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.163	0.837	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.163	0.837	0.000
S65.4 Injury of blood vessel(s) of thumb	0.163	0.837	0.000
S65.3 Injury of deep palmar arch	0.163	0.837	0.000
S65.2 Injury of superficial palmar arch	0.163	0.837	0.000
S62.51 Fracture of thumb (open)	0.163	0.837	0.000
S60.2 Contusion of other parts of wrist and hand	0.162	0.838	0.000
S62.70 Multiple fractures of fingers (closed)	0.160	0.840	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.158	0.842	0.000
S65.1 Injury of radial artery at wrist and hand level	0.156	0.844	0.000
S64.1 Injury of median nerve at wrist and hand level	0.156	0.844	0.000
S62.71 Multiple fractures of fingers (open)	0.154	0.845	0.000
S67 Crushing injury of wrist and hand	0.154	0.846	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.154	0.846	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.154	0.846	0.000
S62.4 Multiple fractures of metacarpal bones	0.152	0.848	0.000
S62.2 Fracture of first metacarpal bone	0.150	0.850	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.148	0.852	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.147	0.853	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.145	0.855	0.000
S69.8 Other specified injuries of wrist and hand	0.144	0.856	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.138	0.862	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.137	0.863	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.135	0.865	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.134	0.866	0.000
S61 Open wound of wrist and hand	0.130	0.870	0.000
S62.31 Fracture of other metacarpal bone (open)	0.128	0.872	0.000
S62.6 Fracture of other finger	0.118	0.882	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.112	0.888	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.111	0.889	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.110	0.890	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.109	0.891	0.000
S62.21 Fracture of first metacarpal bone (open)	0.108	0.892	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.106	0.894	0.000
S61.8 Open wound of other parts of wrist and hand	0.088	0.912	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.084	0.915	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.082	0.918	0.000
S61.7 Multiple open wounds of wrist and hand	0.081	0.919	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.078	0.922	0.000
S62.60 Fracture of other finger (closed)	0.074	0.926	0.000
S61.1 Open wound of finger(s) with damage to nail	0.073	0.927	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.067	0.933	0.000
S61.0 Open wound of finger(s) without damage to nail	0.049	0.951	0.000
S62.61 Fracture of other finger (open)	0.048	0.951	0.000
D73.0 Hyposplenism	0.026	0.974	0.000
D73 Diseases of spleen	0.018	0.982	0.000
D73.1 Hypersplenism	0.016	0.984	0.000
D73.5 Infarction of spleen	0.015	0.985	0.000
D73.4 Cyst of spleen	0.014	0.986	0.000
D73.9 Disease of spleen, unspecified	0.013	0.987	0.000
D73.3 Abscess of spleen	0.013	0.987	0.000
D73.2 Chronic congestive splenomegaly	0.013	0.987	0.000
C92.0 Acute myeloid leukaemia	0.011	0.989	0.000
D73.8 Other diseases of spleen	0.011	0.989	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.011	0.989	0.000
C92 Myeloid leukaemia	0.009	0.991	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.009	0.991	0.000
D75 Other diseases of blood and blood-forming organs	0.009	0.991	0.000
N39.8 Other specified disorders of urinary system	0.009	0.991	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.008	0.992	0.000
D75.2 Essential thrombocytosis	0.008	0.992	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.992	0.008
C92.1 Chronic myeloid leukaemia	0.008	0.992	0.000
C92.9 Myeloid leukaemia, unspecified	0.008	0.992	0.000
D72 Other disorders of white blood cells	0.007	0.993	0.000
C92.4 Acute promyelocytic leukaemia	0.007	0.993	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.007	0.993	0.000
D75.0 Familial erythrocytosis	0.007	0.993	0.000
C92.7 Other myeloid leukaemia	0.007	0.993	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.006	0.993	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.006	0.993	0.000
C92.5 Acute myelomonocytic leukaemia	0.006	0.993	0.000
C92.3 Myeloid sarcoma	0.006	0.993	0.000
C92.2 Subacute myeloid leukaemia	0.006	0.993	0.000
D74 Methaemoglobinaemia	0.006	0.993	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.006	0.993	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.006	0.993	0.000
D72.8 Other specified disorders of white blood cells	0.006	0.994	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.006	0.994	0.000
S82.20 Fracture of shaft of tibia (closed)	0.006	0.994	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.006	0.994	0.000
M88.9 Paget's disease of bone, unspecified	0.006	0.994	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.005	0.995	0.000
D72.9 Disorder of white blood cells, unspecified	0.005	0.995	0.000
D72.0 Genetic anomalies of leukocytes	0.005	0.995	0.000
M79.79 Fibromyalgia (Site unspecified)	0.005	0.995	0.000
D75.1 Secondary polycythaemia	0.005	0.995	0.000
Z03.1 Observation for suspected malignant neoplasm	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.005	0.995	0.000
D74.8 Other methaemoglobinaemias	0.005	0.995	0.000
D74.0 Congenital methaemoglobinaemia	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.004	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.004	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.004	0.995	0.000
M88 Paget's disease of bone [osteitis deformans]	0.005	0.995	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.005	0.995	0.000
D35.1 Parathyroid gland	0.000	0.995	0.005
I86.8 Varicose veins of other specified sites	0.004	0.996	0.000
C44.1 Skin of eyelid, including canthus	0.004	0.996	0.000
N48.0 Leukoplakia of penis	0.004	0.996	0.000
K50.9 Crohn's disease, unspecified	0.000	0.996	0.004
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.004	0.996	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.004	0.996	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.004	0.996	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.004	0.996	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.004	0.996	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.004	0.996	0.000
C54.1 Endometrium	0.004	0.996	0.000
M89.3 Hypertrophy of bone	0.004	0.996	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.996	0.004
M89.37 Hypertrophy of bone (Ankle and foot)	0.004	0.996	0.000
D76.3 Other histiocytosis syndromes	0.004	0.996	0.000
M89 Other disorders of bone	0.004	0.996	0.000
M79.9 Soft tissue disorder, unspecified	0.004	0.996	0.000
D72.1 Eosinophilia	0.004	0.996	0.000
M79.7 Fibromyalgia	0.004	0.996	0.000
M86-M90 Other osteopathies	0.004	0.996	0.000
M89.0 Algoneurodystrophy	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.004	0.996	0.000
M88.8 Paget's disease of other bones	0.003	0.996	0.000
M88.0 Paget's disease of skull	0.003	0.996	0.000
M89.38 Hypertrophy of bone (Other)	0.003	0.996	0.000
M86 Osteomyelitis	0.004	0.996	0.000
M79.70 Fibromyalgia (Multiple sites)	0.003	0.996	0.000
K50.1 Crohn's disease of large intestine	0.000	0.996	0.003
M79.98 Soft tissue disorder, unspecified (Other)	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
M87 Osteonecrosis	0.003	0.997	0.000
M86.9 Osteomyelitis, unspecified	0.003	0.997	0.000
I50.9 Heart failure, unspecified	0.003	0.997	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.003	0.997	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.003	0.997	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.003	0.997	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.003	0.997	0.000
M89.34 Hypertrophy of bone (Hand)	0.003	0.997	0.000
M89.33 Hypertrophy of bone (Forearm)	0.003	0.997	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.003	0.997	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.003	0.997	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.003	0.997	0.000
M89.6 Osteopathy after poliomyelitis	0.003	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.003	0.997	0.000
M89.2 Other disorders of bone development and growth	0.003	0.997	0.000
M89.1 Epiphyseal arrest	0.003	0.997	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.997	0.003
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.003	0.997	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.003	0.997	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.003	0.997	0.000
M79.93 Soft tissue disorder, unspecified (Forearm)	0.003	0.997	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.003	0.997	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.003	0.997	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.003	0.997	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.997	0.003
M79.78 Fibromyalgia (Other)	0.003	0.997	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.003	0.997	0.000
M79.76 Fibromyalgia (Lower leg)	0.003	0.997	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.003	0.997	0.000
M79.74 Fibromyalgia (Hand)	0.003	0.997	0.000
M79.73 Fibromyalgia (Forearm)	0.003	0.997	0.000
M79.72 Fibromyalgia (Upper arm)	0.003	0.997	0.000
M79.71 Fibromyalgia (Shoulder region)	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
M79.09 Rheumatism, unspecified (Site unspecified)	0.003	0.997	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.997	0.003
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
E87.3 Alkalosis	0.003	0.997	0.000
M79.0 Rheumatism, unspecified	0.003	0.997	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.997	0.003
M87.8 Other osteonecrosis	0.003	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.997	0.003
K50.0 Crohn's disease of small intestine	0.000	0.997	0.003
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
I86.4 Gastric varices	0.003	0.997	0.000
K60.3 Anal fistula	0.000	0.997	0.003
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
I77.6 Arteritis, unspecified	0.000	0.997	0.003
M79 Other soft tissue disorders, not elsewhere classified	0.003	0.997	0.000
M88.09 Paget's disease of skull-Site unspec	0.003	0.997	0.000
M88.08 Paget's disease of skull-Other	0.003	0.997	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.003	0.997	0.000
M88.06 Paget's disease of skull-Lower Leg	0.003	0.997	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.003	0.997	0.000
M88.04 Paget's disease of skull-Hand	0.003	0.997	0.000
M88.03 Paget's disease of skull-Forearm	0.003	0.997	0.000
M88.02 Paget's disease of skull-Upper arm	0.003	0.997	0.000
M88.01 Paget's disease of skull-Shldr region	0.003	0.997	0.000
M88.00 Paget's disease of skull-Mult sites	0.003	0.997	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.003	0.997	0.000
M88.88 Paget's disease of other bones (Other)	0.003	0.997	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.003	0.997	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.003	0.997	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.003	0.997	0.000
M88.84 Paget's disease of other bones (Hand)	0.003	0.997	0.000
M88.83 Paget's disease of other bones (Forearm)	0.003	0.997	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.003	0.997	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.003	0.997	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.003	0.997	0.000
M86.8 Other osteomyelitis	0.003	0.997	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.997	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.003	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.997	0.000
M86.2 Subacute osteomyelitis	0.003	0.997	0.000
M86.1 Other acute osteomyelitis	0.003	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.997	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.003	0.997	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.003	0.997	0.000
M89.59 Osteolysis (Site unspecified)	0.003	0.997	0.000
M89.58 Osteolysis (Other)	0.003	0.997	0.000
M89.57 Osteolysis (Ankle and foot)	0.003	0.997	0.000
M89.56 Osteolysis (Lower leg)	0.003	0.997	0.000
M89.54 Osteolysis (Hand)	0.003	0.997	0.000
M89.53 Osteolysis (Forearm)	0.003	0.997	0.000
M89.52 Osteolysis (Upper arm)	0.003	0.997	0.000
M89.51 Osteolysis (Shoulder region)	0.003	0.997	0.000
M89.50 Osteolysis (Multiple sites)	0.003	0.997	0.000
M79.5 Residual foreign body in soft tissue	0.003	0.997	0.000
I86 Varicose veins of other sites	0.003	0.997	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.003	0.997	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.003	0.997	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.003	0.997	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.003	0.997	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.003	0.997	0.000
M87.3 Other secondary osteonecrosis	0.003	0.997	0.000
M87.1 Osteonecrosis due to drugs	0.003	0.997	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.003	0.997	0.000
K60.1 Chronic anal fissure	0.000	0.997	0.003
E87.7 Fluid overload	0.003	0.997	0.000
M11.2 Other chondrocalcinosis	0.003	0.997	0.000
M86.6 Other chronic osteomyelitis	0.003	0.997	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.997	0.003
M86.96 Osteomyelitis, unspecified (Lower leg)	0.003	0.997	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.997	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.997	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.997	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.997	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.997	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.997	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.997	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.997	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.997	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.997	0.003
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.997	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.997	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.997	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.997	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.997	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.997	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.997	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.997	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.997	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.997	0.000
N36.8 Other specified disorders of urethra	0.000	0.997	0.003
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.003	0.997	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.003	0.997	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.997	0.003
K60.5 Anorectal fistula	0.000	0.997	0.003
M79.2 Neuralgia and neuritis, unspecified	0.003	0.997	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.997	0.002
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.997	0.002
E87.6 Hypokalaemia	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
R45.2 Unhappiness	0.000	0.998	0.002
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.002	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.002	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.002	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.002	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.002	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.002	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.002	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.002	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.002	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.002	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.002	0.998	0.000
M90.0 Tuberculosis of bone	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000
K60.0 Acute anal fissure	0.000	0.998	0.002
M79.3 Panniculitis, unspecified	0.002	0.998	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.002	0.998	0.000
K60.4 Rectal fistula	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.002	0.998	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.002	0.998	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.002	0.998	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.18 Other acute osteomyelitis (Other)	0.002	0.998	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.14 Other acute osteomyelitis (Hand)	0.002	0.998	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.002	0.998	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.28 Subacute osteomyelitis (Other)	0.002	0.998	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.24 Subacute osteomyelitis (Hand)	0.002	0.998	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.002	0.998	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.002	0.998	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.002	0.998	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.002	0.998	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.002	0.998	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.998	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.002	0.998	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.002	0.998	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.002	0.998	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.002	0.998	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.002	0.998	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.002	0.998	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.002	0.998	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.002	0.998	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.002	0.998	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.002	0.998	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.88 Other osteomyelitis (Other)	0.002	0.998	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.84 Other osteomyelitis (Hand)	0.002	0.998	0.000
M86.83 Other osteomyelitis (Forearm)	0.002	0.998	0.000
M86.82 Other osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.002	0.998	0.000
E87.5 Hyperkalaemia	0.002	0.998	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.002	0.998	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.002	0.998	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.002	0.998	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.002	0.998	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.002	0.998	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.002	0.998	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.002	0.998	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.002	0.998	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
I86.3 Vulval varices	0.002	0.998	0.000
I86.2 Pelvic varices	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.002	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.002	0.998	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.002	0.998	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.002	0.998	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.002	0.998	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.002	0.998	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations