TreeWAS – Variant ID: rs673604

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10 Insulin-dependent diabetes mellitus	0.058	0.942	0.000
E10.3 With ophthalmic complications	0.056	0.944	0.000
E10.9 Without complications	0.052	0.948	0.000
E10.2 With renal complications	0.049	0.951	0.000
E10.4 With neurological complications	0.048	0.952	0.000
E10.1 With ketoacidosis	0.047	0.953	0.000
E10.8 With unspecified complications	0.046	0.954	0.000
E10.0 With coma	0.046	0.954	0.000
E10.5 With peripheral circulatory complications	0.044	0.956	0.000
E10.7 With multiple complications	0.042	0.958	0.000
E10.6 With other specified complications	0.042	0.958	0.000
E10-E14 Diabetes mellitus	0.042	0.958	0.000
E14 Unspecified diabetes mellitus	0.034	0.966	0.000
E11 Non-insulin-dependent diabetes mellitus	0.033	0.967	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.032	0.968	0.000
E14.3 With ophthalmic complications	0.031	0.969	0.000
E12 Malnutrition-related diabetes mellitus	0.030	0.970	0.000
E13 Other specified diabetes mellitus	0.030	0.970	0.000
E16.2 Hypoglycaemia, unspecified	0.029	0.971	0.000
E11.3 With ophthalmic complications	0.029	0.971	0.000
E11.8 With unspecified complications	0.029	0.971	0.000
E14.8 With unspecified complications	0.027	0.972	0.000
E11.1 With ketoacidosis	0.027	0.973	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.026	0.974	0.000
E11.0 With coma	0.026	0.974	0.000
E16 Other disorders of pancreatic internal secretion	0.025	0.975	0.000
E11.5 With peripheral circulatory complications	0.025	0.975	0.000
E14.7 With multiple complications	0.025	0.975	0.000
E14.6 With other specified complications	0.025	0.975	0.000
E14.5 With peripheral circulatory complications	0.025	0.975	0.000
E14.4 With neurological complications	0.025	0.975	0.000
E14.2 Withrenal complications	0.025	0.975	0.000
E14.1 With ketoacidosis	0.025	0.975	0.000
E14.0 With coma	0.025	0.975	0.000
E11.7 With multiple complications	0.024	0.976	0.000
E11.6 With other specified complications	0.023	0.977	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.022	0.978	0.000
E11.2 With renal complications	0.022	0.978	0.000
E12.9 Without complications	0.022	0.978	0.000
E12.8 With unspecified complications	0.022	0.978	0.000
E12.7 With multiple complications	0.022	0.978	0.000
E12.6 With other specified complications	0.022	0.978	0.000
E12.5 With peripheral circulatory complications	0.022	0.978	0.000
E12.4 With neurological complications	0.022	0.978	0.000
E12.3 With ophthalmic complications	0.022	0.978	0.000
E12.2 With renal complications	0.022	0.978	0.000
E12.1 With ketoacidosis	0.022	0.978	0.000
E12.0 With coma	0.022	0.978	0.000
E13.8 With unspecified complications	0.022	0.978	0.000
E13.7 With multiple complications	0.022	0.978	0.000
E13.6 With other specified complications	0.022	0.978	0.000
E13.5 With peripheral circulatory complications	0.022	0.978	0.000
E13.4 With neurological complications	0.022	0.978	0.000
E13.3 With ophthalmic complications	0.022	0.978	0.000
E13.2 With renal complications	0.022	0.978	0.000
E13.1 With ketoacidosis	0.022	0.978	0.000
E13.0 With coma	0.022	0.978	0.000
N18.5 Chronic kidney disease, stage 5	0.022	0.978	0.000
N18 Chronic renal failure	0.022	0.978	0.000
E13.9 Without complications	0.021	0.979	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.021	0.979	0.000
N18.0 End-stage renal disease	0.021	0.979	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.021	0.979	0.000
R26 Abnormalities of gait and mobility	0.019	0.981	0.000
N18.9 Chronic renal failure, unspecified	0.019	0.981	0.000
N18.1 Chronic kidney disease, stage 1	0.019	0.981	0.000
E40-E46 Malnutrition	0.019	0.981	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.018	0.982	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.018	0.982	0.000
E16.4 Abnormal secretion of gastrin	0.018	0.982	0.000
E16.3 Increased secretion of glucagon	0.018	0.982	0.000
E16.1 Other hypoglycaemia	0.018	0.982	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.018	0.982	0.000
N18.2 Chronic kidney disease, stage 2	0.018	0.982	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.018	0.982	0.000
E46 Unspecified protein-energy malnutrition	0.017	0.983	0.000
R26.3 Immobility	0.017	0.983	0.000
N18.8 Other chronic renal failure	0.017	0.983	0.000
E15 Nondiabetic hypoglycaemic coma	0.016	0.984	0.000
K70 Alcoholic liver disease	0.014	0.986	0.000
E50-E64 Other nutritional deficiencies	0.014	0.986	0.000
N17-N19 Renal failure	0.014	0.986	0.000
R26.1 Paralytic gait	0.014	0.986	0.000
K70.9 Alcoholic liver disease, unspecified	0.014	0.986	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.013	0.986	0.000
E45 Retarded development following protein-energy malnutrition	0.013	0.986	0.000
E43 Unspecified severe protein-energy malnutrition	0.013	0.986	0.000
E42 Marasmic kwashiorkor	0.013	0.986	0.000
E41 Nutritional marasmus	0.013	0.986	0.000
E40 Kwashiorkor	0.013	0.986	0.000
K70.3 Alcoholic cirrhosis of liver	0.013	0.987	0.000
R26.0 Ataxic gait	0.013	0.987	0.000
E11.4 With neurological complications	0.013	0.987	0.000
K70.1 Alcoholic hepatitis	0.013	0.987	0.000
I77.1 Stricture of artery	0.012	0.988	0.000
I73.9 Peripheral vascular disease, unspecified	0.012	0.988	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.012	0.988	0.000
K70.4 Alcoholic hepatic failure	0.012	0.988	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.988	0.012
I77 Other disorders of arteries and arterioles	0.012	0.988	0.000
N17 Acute renal failure	0.012	0.988	0.000
N19 Unspecified renal failure	0.012	0.988	0.000
K70-K77 Diseases of liver	0.011	0.989	0.000
N18.4 Chronic kidney disease, stage 4	0.011	0.989	0.000
I73 Other peripheral vascular diseases	0.011	0.989	0.000
K74 Fibrosis and cirrhosis of liver	0.011	0.989	0.000
E14.9 Without complications	0.011	0.989	0.000
N18.3 Chronic kidney disease, stage 3	0.011	0.989	0.000
E55 Vitamin D deficiency	0.010	0.989	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.010	0.990	0.000
E63 Other nutritional deficiencies	0.010	0.990	0.000
E56 Other vitamin deficiencies	0.010	0.990	0.000
E51 Thiamine deficiency	0.010	0.990	0.000
E50 Vitamin A deficiency	0.010	0.990	0.000
E60 Dietary zinc deficiency	0.010	0.990	0.000
E59 Dietary selenium deficiency	0.010	0.990	0.000
E58 Dietary calcium deficiency	0.010	0.990	0.000
E54 Ascorbic acid deficiency	0.010	0.990	0.000
E52 Niacin deficiency [pellagra]	0.010	0.990	0.000
E53 Deficiency of other B group vitamins	0.010	0.990	0.000
K72 Hepatic failure, not elsewhere classified	0.010	0.990	0.000
E65-E68 Obesity and other hyperalimentation	0.010	0.990	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.010	0.990	0.000
N17.9 Acute renal failure, unspecified	0.010	0.990	0.000
K74.6 Other and unspecified cirrhosis of liver	0.010	0.990	0.000
E44.1 Mild protein-energy malnutrition	0.010	0.990	0.000
E44.0 Moderate protein-energy malnutrition	0.010	0.990	0.000
E20-E35 Disorders of other endocrine glands	0.010	0.990	0.000
K73 Chronic hepatitis, not elsewhere classified	0.010	0.990	0.000
G47.3 Sleep apnoea	0.010	0.990	0.000
I77.6 Arteritis, unspecified	0.010	0.990	0.000
I72 Other aneurysm	0.010	0.990	0.000
K72.9 Hepatic failure, unspecified	0.010	0.990	0.000
D50.8 Other iron deficiency anaemias	0.010	0.990	0.000
I72.4 Aneurysm of artery of lower extremity	0.010	0.990	0.000
K74.5 Biliary cirrhosis, unspecified	0.010	0.990	0.000
E61 Deficiency of other nutrient elements	0.009	0.990	0.000
I77.0 Arteriovenous fistula, acquired	0.009	0.990	0.000
K74.3 Primary biliary cirrhosis	0.009	0.991	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.009	0.991	0.000
E00-E07 Disorders of thyroid gland	0.009	0.991	0.000
K73.9 Chronic hepatitis, unspecified	0.009	0.991	0.000
I77.8 Other specified disorders of arteries and arterioles	0.009	0.991	0.000
N17.0 Acute renal failure with tubular necrosis	0.009	0.991	0.000
I77.5 Necrosis of artery	0.009	0.991	0.000
I77.4 Coeliac artery compression syndrome	0.009	0.991	0.000
I77.3 Arterial fibromuscular dysplasia	0.009	0.991	0.000
I77.2 Rupture of artery	0.009	0.991	0.000
N17.8 Other acute renal failure	0.009	0.991	0.000
N17.2 Acute renal failure with medullary necrosis	0.009	0.991	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.009	0.991	0.000
I73.0 Raynaud's syndrome	0.008	0.992	0.000
K77 Liver disorders in diseases classified elsewhere	0.008	0.992	0.000
K71 Toxic liver disease	0.008	0.992	0.000
I73.8 Other specified peripheral vascular diseases	0.008	0.992	0.000
H66.9 Otitis media, unspecified	0.000	0.992	0.008
I73.1 Thromboangiitis obliterans [Buerger]	0.008	0.992	0.000
I72.2 Aneurysm of renal artery	0.008	0.992	0.000
K74.4 Secondary biliary cirrhosis	0.008	0.992	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.008	0.992	0.000
K74.1 Hepatic sclerosis	0.008	0.992	0.000
E04 Other non-toxic goitre	0.008	0.992	0.000
E04.9 Non-toxic goitre, unspecified	0.008	0.992	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.008	0.992	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.992	0.008
I78 Diseases of capillaries	0.008	0.992	0.000
E34 Other endocrine disorders	0.008	0.992	0.000
K72.0 Acute and subacute hepatic failure	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
E27 Other disorders of adrenal gland	0.008	0.992	0.000
E55.9 Vitamin D deficiency, unspecified	0.008	0.992	0.000
E55.0 Rickets, active	0.008	0.992	0.000
I72.3 Aneurysm of iliac artery	0.008	0.992	0.000
E50.9 Vitamin A deficiency, unspecified	0.008	0.992	0.000
E50.8 Other manifestations of vitamin A deficiency	0.008	0.992	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.008	0.992	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.008	0.992	0.000
E50.5 Vitamin A deficiency with night blindness	0.008	0.992	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.008	0.992	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.008	0.992	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.008	0.992	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.008	0.992	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.008	0.992	0.000
E51.9 Thiamine deficiency, unspecified	0.008	0.992	0.000
E51.8 Other manifestations of thiamine deficiency	0.008	0.992	0.000
E51.2 Wernicke's encephalopathy	0.008	0.992	0.000
E51.1 Beriberi	0.008	0.992	0.000
E56.9 Vitamin deficiency, unspecified	0.008	0.992	0.000
E56.8 Deficiency of other vitamins	0.008	0.992	0.000
E56.1 Deficiency of vitamin K	0.008	0.992	0.000
E56.0 Deficiency of vitamin E	0.008	0.992	0.000
E63.9 Nutritional deficiency, unspecified	0.008	0.992	0.000
E63.8 Other specified nutritional deficiencies	0.008	0.992	0.000
E63.1 Imbalance of constituents of food intake	0.008	0.992	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.008	0.992	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.008	0.992	0.000
E64.8 Sequelae of other nutritional deficiencies	0.008	0.992	0.000
E64.3 Sequelae of rickets	0.008	0.992	0.000
E64.2 Sequelae of vitamin C deficiency	0.008	0.992	0.000
E64.1 Sequelae of vitamin A deficiency	0.008	0.992	0.000
E64.0 Sequelae of protein-energy malnutrition	0.008	0.992	0.000
E65 Localised adiposity	0.008	0.992	0.000
E53.9 Vitamin B deficiency, unspecified	0.008	0.992	0.000
E53.1 Pyridoxine deficiency	0.008	0.992	0.000
E53.0 Riboflavin deficiency	0.008	0.992	0.000
K72.1 Chronic hepatic failure	0.008	0.992	0.000
K70.0 Alcoholic fatty liver	0.007	0.992	0.000
E53.8 Deficiency of other specified B group vitamins	0.008	0.992	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.007	0.992	0.000
E67 Other hyperalimentation	0.007	0.992	0.000
E68 Sequelae of hyperalimentation	0.007	0.992	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.007	0.992	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E32 Diseases of thymus	0.007	0.993	0.000
E31 Polyglandular dysfunction	0.007	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.007	0.993	0.000
E25 Adrenogenital disorders	0.007	0.993	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.007	0.993	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.007	0.993	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.007	0.993	0.000
E26 Hyperaldosteronism	0.007	0.993	0.000
I72.9 Aneurysm of unspecified site	0.007	0.993	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.007	0.993	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.007	0.993	0.000
I72.1 Aneurysm of artery of upper extremity	0.007	0.993	0.000
K75 Other inflammatory liver diseases	0.007	0.993	0.000
I70 Atherosclerosis	0.007	0.993	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.007	0.993	0.000
E61.9 Deficiency of nutrient element, unspecified	0.007	0.993	0.000
E61.8 Deficiency of other specified nutrient elements	0.007	0.993	0.000
E61.7 Deficiency of multiple nutrient elements	0.007	0.993	0.000
E61.6 Vanadium deficiency	0.007	0.993	0.000
E61.5 Molybdenum deficiency	0.007	0.993	0.000
E61.4 Chromium deficiency	0.007	0.993	0.000
E61.3 Manganese deficiency	0.007	0.993	0.000
E61.2 Magnesium deficiency	0.007	0.993	0.000
E61.0 Copper deficiency	0.007	0.993	0.000
E21.3 Hyperparathyroidism, unspecified	0.007	0.993	0.000
I78.1 Naevus, nonneoplastic	0.007	0.993	0.000
E20 Hypoparathyroidism	0.007	0.993	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.007	0.993	0.000
E29 Testicular dysfunction	0.007	0.993	0.000
H33.2 Serous retinal detachment	0.000	0.993	0.007
E34.8 Other specified endocrine disorders	0.007	0.993	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.007	0.993	0.000
E00 Congenital iodine-deficiency syndrome	0.007	0.993	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.007	0.993	0.000
I72.8 Aneurysm of other specified arteries	0.007	0.993	0.000
E04.0 Non-toxic diffuse goitre	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.000
H36.0 Diabetic retinopathy	0.007	0.993	0.000
R25.3 Fasciculation	0.007	0.993	0.000
J30.3 Other allergic rhinitis	0.000	0.993	0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
E61.1 Iron deficiency	0.006	0.994	0.000
K71.9 Toxic liver disease, unspecified	0.006	0.994	0.000
K71.8 Toxic liver disease with other disorders of liver	0.006	0.994	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.006	0.994	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.006	0.994	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.006	0.994	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.006	0.994	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.006	0.994	0.000
K71.2 Toxic liver disease with acute hepatitis	0.006	0.994	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.006	0.994	0.000
K71.0 Toxic liver disease with cholestasis	0.006	0.994	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.006	0.994	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I72.0 Aneurysm of carotid artery	0.006	0.994	0.000
E27.8 Other specified disorders of adrenal gland	0.006	0.994	0.000
J30.4 Allergic rhinitis, unspecified	0.000	0.994	0.006
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
E06 Thyroiditis	0.006	0.994	0.000
R25 Abnormal involuntary movements	0.006	0.994	0.000
E04.8 Other specified non-toxic goitre	0.006	0.994	0.000
K74.0 Hepatic fibrosis	0.006	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.006	0.994	0.000
K75.8 Other specified inflammatory liver diseases	0.006	0.994	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.006	0.994	0.000
I79.1 Aortitis in diseases classified elsewhere	0.006	0.994	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.006	0.994	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.994	0.006
J30.0 Vasomotor rhinitis	0.000	0.994	0.006
I70.8 Atherosclerosis of other arteries	0.006	0.994	0.000
E34.5 Androgen resistance syndrome	0.006	0.994	0.000
E34.4 Constitutional tall stature	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.006	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.006	0.994	0.000
I78.9 Disease of capillaries, unspecified	0.006	0.994	0.000
E24.8 Other Cushing's syndrome	0.006	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.994	0.000
E24.9 Cushing's syndrome, unspecified	0.006	0.994	0.000
E27.5 Adrenomedullary hyperfunction	0.006	0.994	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
E27.0 Other adrenocortical overactivity	0.006	0.994	0.000
E22 Hyperfunction of pituitary gland	0.006	0.994	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.006	0.994	0.000
E34.0 Carcinoid syndrome	0.006	0.994	0.000
E07 Other disorders of thyroid	0.006	0.994	0.000
E67.8 Other specified hyperalimentation	0.005	0.994	0.000
E67.3 Hypervitaminosis D	0.005	0.994	0.000
E67.2 Megavitamin-B6 syndrome	0.005	0.994	0.000
E67.1 Hypercarotenaemia	0.005	0.994	0.000
E67.0 Hypervitaminosis A	0.005	0.994	0.000
I78.8 Other diseases of capillaries	0.006	0.994	0.000
R29.6 Tendency to fall, not elsewhere classified	0.006	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.005	0.994	0.000
E21.4 Other specified disorders of parathyroid gland	0.005	0.994	0.000
E21.2 Other hyperparathyroidism	0.005	0.994	0.000
E28 Ovarian dysfunction	0.005	0.994	0.000
I74 Arterial embolism and thrombosis	0.006	0.994	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.994	0.000
E25.8 Other adrenogenital disorders	0.005	0.994	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.994	0.000
E30.9 Disorder of puberty, unspecified	0.005	0.994	0.000
E30.8 Other disorders of puberty	0.005	0.994	0.000
E30.1 Precocious puberty	0.005	0.994	0.000
E30.0 Delayed puberty	0.005	0.994	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.994	0.000
E31.8 Other polyglandular dysfunction	0.005	0.994	0.000
E31.1 Polyglandular hyperfunction	0.005	0.994	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.994	0.000
E32.9 Disease of thymus, unspecified	0.005	0.994	0.000
E32.8 Other diseases of thymus	0.005	0.994	0.000
E32.1 Abscess of thymus	0.005	0.994	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.994	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.994	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.994	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.994	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.994	0.000
E26.8 Other hyperaldosteronism	0.005	0.994	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.994	0.000
J35.0 Chronic tonsillitis	0.000	0.994	0.005
K75.3 Granulomatous hepatitis, not elsewhere classified	0.005	0.994	0.000
K75.2 Nonspecific reactive hepatitis	0.005	0.994	0.000
K75.1 Phlebitis of portal vein	0.005	0.994	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
I70.9 Generalised and unspecified atherosclerosis	0.005	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
E27.2 Addisonian crisis	0.005	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
E26.0 Primary hyperaldosteronism	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
K50.9 Crohn's disease, unspecified	0.000	0.995	0.005
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.005	0.995	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.005	0.995	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.005	0.995	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.005	0.995	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.005	0.995	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.005	0.995	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.005	0.995	0.000
E04.2 Non-toxic multinodular goitre	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.005	0.995	0.000
I70.0 Atherosclerosis of aorta	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.995	0.000
N03.9 Unspecified	0.005	0.995	0.000
E03 Other hypothyroidism	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
E29.1 Testicular hypofunction	0.005	0.995	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.005	0.995	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.995	0.000
E06.5 Other chronic thyroiditis	0.004	0.995	0.000
E06.4 Drug-induced thyroiditis	0.004	0.995	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.004	0.995	0.000
E06.1 Subacute thyroiditis	0.004	0.995	0.000
E06.0 Acute thyroiditis	0.004	0.995	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.005	0.995	0.000
R25.0 Abnormal head movements	0.004	0.995	0.000
E04.1 Non-toxic single thyroid nodule	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.004	0.995	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.005	0.995	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.995	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.995	0.005
D10.3 Other and unspecified parts of mouth	0.005	0.995	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.995	0.000
E22.8 Other hyperfunction of pituitary gland	0.004	0.995	0.000
E06.3 Autoimmune thyroiditis	0.004	0.996	0.000
E07.1 Dyshormogenetic goitre	0.004	0.996	0.000
E07.0 Hypersecretion of calcitonin	0.004	0.996	0.000
E22.1 Hyperprolactinaemia	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
R94.5 Abnormal results of liver function studies	0.004	0.996	0.000
E07.8 Other specified disorders of thyroid	0.004	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.004	0.996	0.000
E28.8 Other ovarian dysfunction	0.004	0.996	0.000
E28.1 Androgen excess	0.004	0.996	0.000
E28.0 Oestrogen excess	0.004	0.996	0.000
J35.1 Hypertrophy of tonsils	0.000	0.996	0.004
I74.9 Embolism and thrombosis of unspecified artery	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.004	0.996	0.000
J36 Peritonsillar abscess	0.000	0.996	0.004
K50 Crohn's disease [regional enteritis]	0.000	0.996	0.004
R29.4 Clicking hip	0.004	0.996	0.000
R29.3 Abnormal posture	0.004	0.996	0.000
R29.2 Abnormal reflex	0.004	0.996	0.000
R29.1 Meningismus	0.004	0.996	0.000
R29.0 Tetany	0.004	0.996	0.000
Y83.6 Removal of other organ (partial) (total)	0.004	0.996	0.000
E28.3 Primary ovarian failure	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.996	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.004	0.996	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.996	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.996	0.000
K75.4 Autoimmune hepatitis	0.004	0.996	0.000
E06.9 Thyroiditis, unspecified	0.004	0.996	0.000
I74.8 Embolism and thrombosis of other arteries	0.004	0.996	0.000
K50.8 Other Crohn's disease	0.000	0.996	0.004
E23.2 Diabetes insipidus	0.004	0.996	0.000
K75.0 Abscess of liver	0.004	0.996	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.004	0.996	0.000
E22.0 Acromegaly and pituitary gigantism	0.004	0.996	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.004	0.996	0.000
R25.1 Tremor, unspecified	0.004	0.996	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.996	0.000
K50.1 Crohn's disease of large intestine	0.000	0.996	0.004
I64 Stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.996	0.004
E23.0 Hypopituitarism	0.004	0.996	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.004	0.996	0.000
E03.5 Myxoedema coma	0.004	0.996	0.000
E03.4 Atrophy of thyroid (acquired)	0.004	0.996	0.000
E03.3 Postinfectious hypothyroidism	0.004	0.996	0.000
E03.1 Congenital hypothyroidism without goitre	0.004	0.996	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.004	0.996	0.000
E03.8 Other specified hypothyroidism	0.004	0.996	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.996	0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.003	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.996	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.996	0.000
R27 Other lack of coordination	0.003	0.996	0.000
K50.0 Crohn's disease of small intestine	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.003	0.996	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.996	0.003
J35.2 Hypertrophy of adenoids	0.000	0.996	0.003
K76 Other diseases of liver	0.004	0.996	0.000
N28.1 Cyst of kidney, acquired	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
S01.1 Open wound of eyelid and periocular area	0.000	0.997	0.003
J37 Chronic laryngitis and laryngotracheitis	0.000	0.997	0.003
N03 Chronic nephritic syndrome	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.997	0.003
Y45.1 Salicylates	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
R63.0 Anorexia	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
K76.7 Hepatorenal syndrome	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
R10.1 Pain localised to upper abdomen	0.003	0.997	0.000
G47 Sleep disorders	0.003	0.997	0.000
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.002	0.997	0.000
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
J37.0 Chronic laryngitis	0.000	0.997	0.003
I11.9 Hypertensive heart disease without (congestive) heart failure	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.003	0.997	0.000
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.003	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.003	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.997	0.000
J38.3 Other diseases of vocal cords	0.000	0.997	0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
K76.5 Hepatic veno-occlusive disease	0.003	0.997	0.000
K76.4 Peliosis hepatis	0.003	0.997	0.000
K76.3 Infarction of liver	0.003	0.997	0.000
K76.2 Central haemorrhagic necrosis of liver	0.003	0.997	0.000
K76.1 Chronic passive congestion of liver	0.003	0.997	0.000
M06.3 Rheumatoid nodule	0.003	0.997	0.000
H50.2 Vertical strabismus	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations