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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs676388
log Bayes Factor = 19.9316
Chromosome 19   position 49,211,969  (GRCh37) Explore rs676388 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.000 1.000
K29 Gastritis and duodenitis
0.000 0.000 1.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
K29.8 Duodenitis
0.000 0.001 0.999
K26 Duodenal ulcer
0.000 0.002 0.998
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.002 0.998
K82 Other diseases of gallbladder
0.000 0.005 0.995
K65-K67 Diseases of peritoneum
0.000 0.009 0.991
K29.5 Chronic gastritis, unspecified
0.000 0.014 0.986
K66 Other disorders of peritoneum
0.000 0.017 0.983
K70-K77 Diseases of liver
0.000 0.020 0.980
K82.4 Cholesterolosis of gallbladder
0.000 0.022 0.978
K66.0 Peritoneal adhesions
0.000 0.025 0.975
K29.0 Acute haemorrhagic gastritis
0.000 0.029 0.971
K70 Alcoholic liver disease
0.000 0.038 0.962
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.042 0.958
K31 Other diseases of stomach and duodenum
0.000 0.044 0.956
K70.3 Alcoholic cirrhosis of liver
0.000 0.045 0.955
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.047 0.953
K82.8 Other specified diseases of gallbladder
0.000 0.047 0.953
I83 Varicose veins of lower extremities
0.000 0.048 0.952
I80 Phlebitis and thrombophlebitis
0.000 0.054 0.946
K31.8 Other specified diseases of stomach and duodenum
0.000 0.055 0.945
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.055 0.945
E78.0 Pure hypercholesterolaemia
0.000 0.098 0.902
K29.4 Chronic atrophic gastritis
0.000 0.099 0.901
K66.8 Other specified disorders of peritoneum
0.000 0.102 0.898
K83 Other diseases of biliary tract
0.000 0.103 0.897
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.111 0.889
K82.9 Disease of gallbladder, unspecified
0.000 0.112 0.888
K76 Other diseases of liver
0.000 0.113 0.887
K83.1 Obstruction of bile duct
0.000 0.128 0.872
I10-I15 Hypertensive diseases
0.000 0.133 0.867
K50-K52 Noninfective enteritis and colitis
0.000 0.152 0.848
K50 Crohn's disease [regional enteritis]
0.000 0.165 0.835
Chapter IX Diseases of the circulatory system
0.000 0.169 0.831
K50.1 Crohn's disease of large intestine
0.000 0.172 0.828
I85 Oesophageal varices
0.000 0.175 0.825
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.187 0.813
K83.0 Cholangitis
0.000 0.188 0.812
K74 Fibrosis and cirrhosis of liver
0.000 0.188 0.812
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.195 0.805
K76.8 Other specified diseases of liver
0.000 0.195 0.805
K26.1 Acute with perforation
0.000 0.200 0.800
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.210 0.790
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.223 0.777
K73 Chronic hepatitis, not elsewhere classified
0.000 0.231 0.769
K65 Peritonitis
0.000 0.231 0.769
K27 Peptic ulcer, site unspecified
0.000 0.231 0.769
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.244 0.756
K80.8 Other cholelithiasis
0.000 0.250 0.750
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.260 0.740
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.263 0.737
K26.2 Acute with both haemorrhage and perforation
0.000 0.266 0.734
K66.9 Disorder of peritoneum, unspecified
0.000 0.269 0.731
I85.9 Oesophageal varices without bleeding
0.000 0.271 0.729
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.272 0.728
K29.2 Alcoholic gastritis
0.000 0.273 0.727
K31.4 Gastric diverticulum
0.000 0.275 0.725
I88 Nonspecific lymphadenitis
0.000 0.276 0.724
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.276 0.724
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.283 0.717
K29.9 Gastroduodenitis, unspecified
0.000 0.283 0.717
K70.9 Alcoholic liver disease, unspecified
0.000 0.287 0.713
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.289 0.710
K74.0 Hepatic fibrosis
0.000 0.292 0.708
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.296 0.704
K26.7 Chronic without haemorrhage or perforation
0.000 0.311 0.689
I82 Other venous embolism and thrombosis
0.000 0.311 0.689
K31.0 Acute dilatation of stomach
0.000 0.312 0.688
K76.1 Chronic passive congestion of liver
0.000 0.316 0.683
K26.0 Acute with haemorrhage
0.000 0.317 0.683
K65.8 Other peritonitis
0.000 0.317 0.683
K70.4 Alcoholic hepatic failure
0.000 0.322 0.678
K26.4 Chronic or unspecified with haemorrhage
0.000 0.322 0.678
K82.3 Fistula of gallbladder
0.000 0.322 0.678
I26 Pulmonary embolism
0.000 0.322 0.678
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.322 0.678
K29.3 Chronic superficial gastritis
0.000 0.325 0.675
K31.3 Pylorospasm, not elsewhere classified
0.000 0.331 0.669
K77 Liver disorders in diseases classified elsewhere
0.000 0.334 0.666
K27.7 Chronic without haemorrhage or perforation
0.000 0.337 0.663
I15 Secondary hypertension
0.000 0.339 0.660
K76.6 Portal hypertension
0.000 0.341 0.659
K74.6 Other and unspecified cirrhosis of liver
0.000 0.345 0.655
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.349 0.651
K50.9 Crohn's disease, unspecified
0.000 0.352 0.648
K76.7 Hepatorenal syndrome
0.000 0.354 0.646
K83.5 Biliary cyst
0.000 0.357 0.643
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.357 0.643
K31.6 Fistula of stomach and duodenum
0.000 0.358 0.642
K76.5 Hepatic veno-occlusive disease
0.000 0.364 0.636
K76.4 Peliosis hepatis
0.000 0.364 0.636
K76.3 Infarction of liver
0.000 0.364 0.636
K76.2 Central haemorrhagic necrosis of liver
0.000 0.364 0.636
K50.8 Other Crohn's disease
0.000 0.365 0.635
K28 Gastrojejunal ulcer
0.000 0.377 0.622
I13 Hypertensive heart and renal disease
0.000 0.378 0.622
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.378 0.622
K72 Hepatic failure, not elsewhere classified
0.000 0.378 0.622
K26.3 Acute without haemorrhage or perforation
0.000 0.378 0.622
K82.0 Obstruction of gallbladder
0.000 0.379 0.621
K82.2 Perforation of gallbladder
0.000 0.380 0.619
I85.0 Oesophageal varices with bleeding
0.000 0.385 0.615
K74.5 Biliary cirrhosis, unspecified
0.000 0.390 0.609
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.399 0.601
I28 Other diseases of pulmonary vessels
0.000 0.404 0.596
K83.9 Disease of biliary tract, unspecified
0.000 0.408 0.592
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.409 0.591
I87 Other disorders of veins
0.000 0.409 0.591
K29.1 Other acute gastritis
0.000 0.411 0.589
K25 Gastric ulcer
0.000 0.415 0.585
K70.0 Alcoholic fatty liver
0.000 0.417 0.583
K74.4 Secondary biliary cirrhosis
0.000 0.418 0.582
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.418 0.582
K73.9 Chronic hepatitis, unspecified
0.000 0.418 0.582
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.419 0.581
K71 Toxic liver disease
0.000 0.420 0.580
K74.1 Hepatic sclerosis
0.000 0.421 0.579
I82.2 Embolism and thrombosis of vena cava
0.000 0.427 0.573
K31.5 Obstruction of duodenum
0.000 0.431 0.569
I00-I02 Acute rheumatic fever
0.000 0.437 0.562
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.439 0.561
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.448 0.552
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.448 0.552
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.449 0.551
K27.5 Chronic or unspecified with perforation
0.000 0.449 0.551
K27.4 Chronic or unspecified with haemorrhage
0.000 0.449 0.551
K27.2 Acute with both haemorrhage and perforation
0.000 0.449 0.551
K27.1 Acute with perforation
0.000 0.449 0.551
K27.0 Acute with haemorrhage
0.000 0.449 0.551
K83.4 Spasm of sphincter of Oddi
0.000 0.451 0.549
I15.9 Seconday hypertension, unspecified
0.000 0.451 0.548
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.457 0.543
K23.1 Megaoesophagus in Chagas' disease
0.000 0.458 0.542
K23.0 Tuberculous oesophagitis
0.000 0.458 0.542
I86 Varicose veins of other sites
0.000 0.461 0.539
K83.2 Perforation of bile duct
0.000 0.464 0.535
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.471 0.529
I82.0 Budd-Chiari syndrome
0.000 0.472 0.528
K70.1 Alcoholic hepatitis
0.000 0.474 0.525
K25.3 Acute without haemorrhage or perforation
0.000 0.475 0.525
N80.0 Endometriosis of uterus
0.000 0.476 0.524
K83.3 Fistula of bile duct
0.000 0.481 0.519
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.481 0.519
I11 Hypertensive heart disease
0.000 0.481 0.519
K26.5 Chronic or unspecified with perforation
0.000 0.484 0.516
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.486 0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.486 0.514
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.486 0.514
K27.3 Acute without haemorrhage or perforation
0.000 0.489 0.511
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.490 0.509
K67.3 Tuberculous peritonitis
0.000 0.490 0.509
K67.2 Syphilitic peritonitis
0.000 0.490 0.509
K67.1 Gonococcal peritonitis
0.000 0.490 0.509
K67.0 Chlamydial peritonitis
0.000 0.490 0.509
I88.8 Other nonspecific lymphadenitis
0.000 0.492 0.508
I28.8 Other specified diseases of pulmonary vessels
0.000 0.496 0.504
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.504 0.496
K65.0 Acute peritonitis
0.000 0.505 0.495
I82.1 Thrombophlebitis migrans
0.000 0.506 0.494
K82.1 Hydrops of gallbladder
0.000 0.508 0.491
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.509 0.491
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.518 0.482
K90-K93 Other diseases of the digestive system
0.000 0.520 0.480
I81 Portal vein thrombosis
0.000 0.521 0.479
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.522 0.478
I15.8 Other secondary hypertension
0.000 0.526 0.474
I15.2 Hypertension secondary to endocrine disorders
0.000 0.526 0.474
K85 Acute pancreatitis
0.000 0.530 0.470
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.531 0.469
N80 Endometriosis
0.000 0.533 0.467
I15.1 Hypertension secondary to other renal disorders
0.000 0.534 0.466
K25.5 Chronic or unspecified with perforation
0.000 0.545 0.455
I82.3 Embolism and thrombosis of renal vein
0.000 0.548 0.452
K65.9 Peritonitis, unspecified
0.000 0.548 0.452
K72.9 Hepatic failure, unspecified
0.000 0.551 0.449
K28.7 Chronic without haemorrhage or perforation
0.000 0.553 0.446
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.553 0.446
K28.5 Chronic or unspecified with perforation
0.000 0.553 0.446
K28.4 Chronic or unspecified with haemorrhage
0.000 0.553 0.446
K28.3 Acute without haemorrhage or perforation
0.000 0.553 0.446
K28.2 Acute with both haemorrhage and perforation
0.000 0.553 0.446
K28.1 Acute with perforation
0.000 0.553 0.446
K28.0 Acute with haemorrhage
0.000 0.553 0.446
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.554 0.446
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.554 0.446
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.554 0.446
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.554 0.446
N80.1 Endometriosis of ovary
0.000 0.558 0.442
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.559 0.441
K25.4 Chronic or unspecified with haemorrhage
0.000 0.561 0.439
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.568 0.432
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.571 0.429
I28.1 Aneurysm of pulmonary artery
0.000 0.572 0.427
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.572 0.427
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.575 0.425
K72.0 Acute and subacute hepatic failure
0.000 0.576 0.424
I87.0 Postphlebitic syndrome
0.000 0.576 0.423
I15.0 Renovascular hypertension
0.000 0.577 0.423
K71.0 Toxic liver disease with cholestasis
0.000 0.578 0.421
N80.5 Endometriosis of intestine
0.000 0.579 0.421
K25.2 Acute with both haemorrhage and perforation
0.000 0.580 0.420
K25.1 Acute with perforation
0.000 0.580 0.420
I86.4 Gastric varices
0.000 0.584 0.416
K71.9 Toxic liver disease, unspecified
0.000 0.584 0.416
K71.8 Toxic liver disease with other disorders of liver
0.000 0.584 0.416
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.584 0.416
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.584 0.416
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.584 0.416
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.584 0.416
K71.2 Toxic liver disease with acute hepatitis
0.000 0.584 0.416
K80.4 Calculus of bile duct with cholecystitis
0.000 0.590 0.410
K50.0 Crohn's disease of small intestine
0.000 0.593 0.407
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.595 0.405
N80.8 Other endometriosis
0.000 0.595 0.405
I02 Rheumatic chorea
0.000 0.596 0.403
I01 Rheumatic fever with heart involvement
0.000 0.596 0.403
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.598 0.402
I86.8 Varicose veins of other specified sites
0.000 0.600 0.400
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.601 0.399
K25.0 Acute with haemorrhage
0.000 0.602 0.398
N80.4 Endometriosis of rectovaginal septum and vagina
0.000 0.605 0.395
K85.8 Other acute pancreatitis
0.000 0.605 0.395
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.606 0.394
N80.2 Endometriosis of Fallopian tube
0.000 0.609 0.390
K72.1 Chronic hepatic failure
0.000 0.612 0.388
I86.0 Sublingual varices
0.000 0.613 0.387
K76.9 Liver disease, unspecified
0.000 0.614 0.386
I87.9 Disorder of vein, unspecified
0.000 0.617 0.382
K25.7 Chronic without haemorrhage or perforation
0.000 0.625 0.375
I86.3 Vulval varices
0.000 0.626 0.374
K74.3 Primary biliary cirrhosis
0.000 0.628 0.372
I60-I69 Cerebrovascular diseases
0.000 0.629 0.371
I00 Rheumatic fever without mention of heart involvement
0.000 0.630 0.370
I86.2 Pelvic varices
0.000 0.631 0.369
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.635 0.365
K91.4 Colostomy and enterostomy malfunction
0.000 0.645 0.355
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.646 0.354
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.648 0.352
I82.8 Embolism and thrombosis of other specified veins
0.000 0.650 0.350
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.656 0.344
K29.6 Other gastritis
0.000 0.656 0.344
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.663 0.337
I12 Hypertensive renal disease
0.000 0.666 0.334
K40-K46 Hernia
0.000 0.666 0.334
I61 Intracerebral haemorrhage
0.000 0.671 0.329
I63 Cerebral infarction
0.000 0.673 0.327
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.677 0.323
I60 Subarachnoid haemorrhage
0.000 0.677 0.323
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.682 0.318
K75 Other inflammatory liver diseases
0.000 0.686 0.314
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.687 0.313
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.688 0.312
K85.3 Drug-induced acute pancreatitis
0.000 0.688 0.312
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.689 0.311
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.690 0.310
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.690 0.310
I98.0 Cardiovascular syphilis
0.000 0.690 0.310
K91.1 Postgastric surgery syndromes
0.000 0.691 0.309
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.692 0.308
K85.1 Biliary acute pancreatitis
0.000 0.692 0.308
K91.5 Postcholecystectomy syndrome
0.000 0.692 0.308
K35-K38 Diseases of appendix
0.000 0.694 0.306
K85.0 Idiopathic acute pancreatitis
0.000 0.699 0.301
I72 Other aneurysm
0.000 0.701 0.299
K43 Ventral hernia
0.000 0.704 0.296
N80.6 Endometriosis in cutaneous scar
0.000 0.706 0.294
I87.8 Other specified disorders of veins
0.000 0.709 0.291
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.710 0.289
I01.8 Other acute rheumatic heart disease
0.000 0.710 0.289
I01.2 Acute rheumatic myocarditis
0.000 0.710 0.289
I01.1 Acute rheumatic endocarditis
0.000 0.710 0.289
I01.0 Acute rheumatic pericarditis
0.000 0.710 0.289
I02.9 Rheumatic chorea without heart involvement
0.000 0.710 0.289
I02.0 Rheumatic chorea with heart involvement
0.000 0.710 0.289
K52 Other non-infective gastro-enteritis and colitis
0.000 0.711 0.289
I87.1 Compression of vein
0.000 0.716 0.284
K41 Femoral hernia
0.000 0.717 0.283
K66.1 Haemoperitoneum
0.002 0.717 0.280
K83.8 Other specified diseases of biliary tract
0.000 0.718 0.282
K85.9 Acute pancreatitis, unspecified
0.000 0.719 0.281
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.719 0.281
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.721 0.279
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.723 0.277
K91.3 Postoperative intestinal obstruction
0.000 0.726 0.274
K75.0 Abscess of liver
0.000 0.728 0.272
I72.4 Aneurysm of artery of lower extremity
0.000 0.728 0.272
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.728 0.272
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.729 0.271
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.730 0.270
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.731 0.269
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.737 0.263
I63.9 Cerebral infarction, unspecified
0.000 0.739 0.261
I70 Atherosclerosis
0.000 0.740 0.260
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.743 0.257
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.748 0.252
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.748 0.252
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.750 0.250
I61.8 Other intracerebral haemorrhage
0.000 0.750 0.250
K46 Unspecified abdominal hernia
0.000 0.752 0.248
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.753 0.247
K93.1 Megacolon in Chagas' disease
0.000 0.753 0.247
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.753 0.247
I74 Arterial embolism and thrombosis
0.000 0.754 0.246
I72.9 Aneurysm of unspecified site
0.000 0.755 0.245
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.755 0.245
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.755 0.245
I71 Aortic aneurysm and dissection
0.000 0.757 0.243
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.761 0.239
I72.0 Aneurysm of carotid artery
0.000 0.761 0.239
K52.1 Toxic gastro-enteritis and colitis
0.000 0.763 0.237
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.765 0.235
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.765 0.235
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.765 0.234
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.765 0.234
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.766 0.234
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.768 0.232
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.770 0.230
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.770 0.230
I72.2 Aneurysm of renal artery
0.000 0.770 0.230
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.772 0.228
K75.2 Nonspecific reactive hepatitis
0.000 0.775 0.225
K75.1 Phlebitis of portal vein
0.000 0.775 0.225
I99 Other and unspecified disorders of circulatory system
0.000 0.776 0.224
I70.0 Atherosclerosis of aorta
0.000 0.779 0.221
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.781 0.219
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.782 0.218
I05-I09 Chronic rheumatic heart diseases
0.000 0.782 0.218
K85.2 Alcohol-induced acute pancreatitis
0.001 0.783 0.216
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.785 0.215
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.785 0.214
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.785 0.214
K36 Other appendicitis
0.000 0.786 0.214
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.787 0.213
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.787 0.213
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.787 0.213
K43.4 Parastomal hernia with gangrene
0.000 0.787 0.213
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.787 0.213
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.787 0.213
K43.1 Ventral hernia with gangrene
0.000 0.787 0.213
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.788 0.212
I86.1 Scrotal varices
0.000 0.789 0.211
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.789 0.211
I89.1 Lymphangitis
0.000 0.793 0.207
I95 Hypotension
0.000 0.793 0.207
K52.3 Indeterminate colitis
0.000 0.795 0.205
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.795 0.205
I60.8 Other subarachnoid haemorrhage
0.000 0.796 0.204
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.797 0.203
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.797 0.203
I62 Other nontraumatic intracranial haemorrhage
0.000 0.798 0.202
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.799 0.201
I70.1 Atherosclerosis of renal artery
0.000 0.800 0.200
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.803 0.197
I65.1 Occlusion and stenosis of basilar artery
0.000 0.803 0.196
I12.9 Hypertensive renal disease without renal failure
0.000 0.803 0.196
K38 Other diseases of appendix
0.000 0.805 0.195
K90 Intestinal malabsorption
0.000 0.806 0.194
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.806 0.194
K81 Cholecystitis
0.000 0.806 0.194
K45 Other abdominal hernia
0.000 0.807 0.193
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.807 0.193
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.809 0.191
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.809 0.191
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.809 0.190
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.809 0.191
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.809 0.190
I89.0 Lymphoedema, not elsewhere classified
0.000 0.811 0.189
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.811 0.188
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.811 0.188
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.813 0.187
I70.9 Generalised and unspecified atherosclerosis
0.000 0.813 0.187
I72.1 Aneurysm of artery of upper extremity
0.000 0.814 0.186
I72.3 Aneurysm of iliac artery
0.000 0.814 0.186
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.815 0.185
I74.5 Embolism and thrombosis of iliac artery
0.000 0.816 0.184
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.817 0.183
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.818 0.181
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.819 0.181
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.819 0.181
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.819 0.181
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.819 0.181
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.819 0.181
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.819 0.181
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.822 0.178
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.822 0.178
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.822 0.178
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.822 0.178
I27 Other pulmonary heart diseases
0.000 0.825 0.175
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.825 0.175
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.825 0.175
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.826 0.174
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.826 0.174
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.826 0.174
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.826 0.173
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.827 0.173
K21 Gastro-oesophageal reflux disease
0.000 0.829 0.171
I77 Other disorders of arteries and arterioles
0.000 0.829 0.171
I72.8 Aneurysm of other specified arteries
0.000 0.830 0.170
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.831 0.169
I95.2 Hypotension due to drugs
0.000 0.832 0.168
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.832 0.168
I69 Sequelae of cerebrovascular disease
0.000 0.833 0.167
I68.0 Cerebral amyloid angiopathy
0.000 0.833 0.167
K75.4 Autoimmune hepatitis
0.000 0.839 0.161
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.839 0.161
I95.0 Idiopathic hypotension
0.000 0.840 0.160
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.841 0.159
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.841 0.159
I06 Rheumatic aortic valve diseases
0.000 0.841 0.159
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.842 0.158
I63.8 Other cerebral infarction
0.000 0.842 0.158
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.842 0.157
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.842 0.157
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.844 0.156
I07 Rheumatic tricuspid valve diseases
0.000 0.845 0.155
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.846 0.154
I62.1 Nontraumatic extradural haemorrhage
0.000 0.846 0.154
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.848 0.152
I70.8 Atherosclerosis of other arteries
0.000 0.848 0.152
I97.0 Postcardiotomy syndrome
0.000 0.848 0.152
I27.9 Pulmonary heart disease, unspecified
0.000 0.850 0.150
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.850 0.150
K38.0 Hyperplasia of appendix
0.000 0.851 0.149
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.852 0.148
I69.3 Sequelae of cerebral infarction
0.000 0.853 0.147
I09 Other rheumatic heart diseases
0.000 0.855 0.145
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.855 0.145
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.856 0.144
I95.8 Other hypotension
0.000 0.857 0.143
I77.8 Other specified disorders of arteries and arterioles
0.000 0.857 0.143
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.859 0.141
I77.6 Arteritis, unspecified
0.000 0.860 0.140
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.860 0.140
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.860 0.140
K38.3 Fistula of appendix
0.000 0.860 0.140
K38.9 Disease of appendix, unspecified
0.000 0.860 0.140
K90.3 Pancreatic steatorrhoea
0.000 0.861 0.139
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.861 0.139
K90.1 Tropical sprue
0.000 0.861 0.139
K45.1 Other specified abdominal hernia with gangrene
0.000 0.861 0.138
N80.3 Endometriosis of pelvic peritoneum
0.000 0.862 0.138
K38.1 Appendicular concretions
0.000 0.863 0.137
I79.1 Aortitis in diseases classified elsewhere
0.000 0.863 0.137
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.863 0.137
I78 Diseases of capillaries
0.000 0.864 0.136
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.864 0.136
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.866 0.134
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.866 0.134
K90.8 Other intestinal malabsorption
0.000 0.866 0.134
K44 Diaphragmatic hernia
0.000 0.867 0.133
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.867 0.133
K35 Acute appendicitis
0.000 0.867 0.133
K81.1 Chronic cholecystitis
0.000 0.868 0.132
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.870 0.130
I97.1 Other functional disturbances following cardiac surgery
0.000 0.870 0.129
K38.2 Diverticulum of appendix
0.000 0.870 0.129
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.872 0.128
I73 Other peripheral vascular diseases
0.000 0.873 0.127
K75.9 Inflammatory liver disease, unspecified
0.000 0.873 0.126
I27.1 Kyphoscoliotic heart disease
0.000 0.874 0.126
K37 Unspecified appendicitis
0.000 0.875 0.125
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.001 0.875 0.125
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.876 0.124
I77.5 Necrosis of artery
0.000 0.877 0.123
I77.4 Coeliac artery compression syndrome
0.000 0.877 0.123
I06.0 Rheumatic aortic stenosis
0.000 0.878 0.122
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.879 0.121
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.880 0.119
K38.8 Other specified diseases of appendix
0.000 0.881 0.119
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.881 0.119
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.881 0.119
I77.3 Arterial fibromuscular dysplasia
0.000 0.881 0.119
K86 Other diseases of pancreas
0.000 0.883 0.117
I06.8 Other rheumatic aortic valve diseases
0.000 0.886 0.114
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.886 0.114
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.886 0.114
I06.1 Rheumatic aortic insufficiency
0.000 0.887 0.112
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.888 0.112
I07.9 Tricuspid valve disease, unspecified
0.000 0.889 0.111
I07.8 Other tricuspid valve diseases
0.000 0.889 0.111
I07.2 Tricuspid stenosis with insufficiency
0.000 0.889 0.111
I07.0 Tricuspid stenosis
0.000 0.889 0.111
K90.9 Intestinal malabsorption, unspecified
0.000 0.889 0.111
K81.9 Cholecystitis, unspecified
0.000 0.890 0.110
I07.1 Tricuspid insufficiency
0.000 0.890 0.110
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.890 0.109
K75.8 Other specified inflammatory liver diseases
0.000 0.891 0.109
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.891 0.109
N80.9 Endometriosis, unspecified
0.000 0.892 0.108
I71.0 Dissection of aorta [any part]
0.000 0.892 0.108

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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