TreeWAS – Variant ID: rs6782264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.149	0.851
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.154	0.846
I25.1 Atherosclerotic heart disease	0.000	0.166	0.834
I20-I25 Ischaemic heart diseases	0.000	0.173	0.827
I20 Angina pectoris	0.000	0.191	0.809
I20.9 Angina pectoris, unspecified	0.000	0.196	0.804
I24 Other acute ischaemic heart diseases	0.000	0.257	0.743
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.263	0.737
I22 Subsequent myocardial infarction	0.000	0.317	0.683
I24.8 Other forms of acute ischaemic heart disease	0.000	0.327	0.673
I25.2 Old myocardial infarction	0.000	0.355	0.645
I25.6 Silent myocardial ischaemia	0.000	0.389	0.610
I25.5 Ischaemic cardiomyopathy	0.000	0.389	0.610
I25.4 Coronary artery aneurysm	0.000	0.389	0.610
I25.3 Aneurysm of heart	0.000	0.389	0.610
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.389	0.610
I23 Certain current complications following acute myocardial infarction	0.000	0.407	0.593
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.411	0.589
I20.1 Angina pectoris with documented spasm	0.000	0.417	0.583
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.438	0.562
I24.1 Dressler's syndrome	0.000	0.467	0.533
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.467	0.533
I21 Acute myocardial infarction	0.000	0.467	0.533
I20.0 Unstable angina	0.000	0.501	0.499
I22.8 Subsequent myocardial infarction of other sites	0.000	0.510	0.489
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.510	0.489
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.531	0.469
I20.8 Other forms of angina pectoris	0.000	0.537	0.462
I23.8 Other current complications following acute myocardial infarction	0.000	0.575	0.425
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.575	0.425
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.575	0.425
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.575	0.425
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.575	0.425
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.575	0.425
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.575	0.425
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.575	0.425
I21.9 Acute myocardial infarction, unspecified	0.000	0.584	0.416
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.590	0.410
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.597	0.403
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.618	0.382
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.618	0.382
I21.4 Acute subendocardial myocardial infarction	0.000	0.662	0.338
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.770	0.230
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.181	0.819	0.000
M20-M25 Other joint disorders	0.177	0.823	0.000
M50-M54 Other dorsopathies	0.175	0.825	0.000
M45-M49 Spondylopathies	0.173	0.827	0.000
M23 Internal derangement of knee	0.170	0.830	0.000
M47 Spondylosis	0.166	0.834	0.000
M23.3 Other meniscus derangements	0.157	0.843	0.000
M50 Cervical disk disorders	0.157	0.843	0.000
M65-M68 Disorders of synovium and tendon	0.155	0.845	0.000
M25 Other joint disorders, not elsewhere classified	0.155	0.845	0.000
M54 Dorsalgia	0.153	0.847	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.150	0.850	0.000
M51 Other intervertebral disk disorders	0.148	0.852	0.000
M15-M19 Arthrosis	0.147	0.853	0.000
M40-M43 Deforming dorsopathies	0.146	0.854	0.000
M80-M85 Disorders of bone density and structure	0.145	0.855	0.000
M47.9 Spondylosis, unspecified	0.145	0.855	0.000
M47.2 Other spondylosis with radiculopathy	0.143	0.857	0.000
M25.7 Osteophyte	0.143	0.857	0.000
M47.8 Other spondylosis	0.142	0.858	0.000
M00-M03 Infectious arthropathies	0.141	0.858	0.000
M21 Other acquired deformities of limbs	0.141	0.859	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.139	0.860	0.000
M86-M90 Other osteopathies	0.139	0.861	0.000
M46 Other inflammatory spondylopathies	0.138	0.862	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.138	0.862	0.000
M65 Synovitis and tenosynovitis	0.136	0.864	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.136	0.864	0.000
M31 Other necrotising vasculopathies	0.136	0.864	0.000
M19 Other arthrosis	0.136	0.864	0.000
M54.5 Low back pain	0.135	0.865	0.000
M20 Acquired deformities of fingers and toes	0.132	0.867	0.000
M50.1 Cervical disk disorder with radiculopathy	0.131	0.869	0.000
M23.4 Loose body in knee	0.131	0.869	0.000
M50.2 Other cervical disk displacement	0.130	0.870	0.000
M91-M94 Chondropathies	0.130	0.870	0.000
M60-M63 Disorders of muscles	0.130	0.870	0.000
M48 Other spondylopathies	0.129	0.871	0.000
M54.56 Low back pain (Lumbar region)	0.127	0.873	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.127	0.873	0.000
M34 Systemic sclerosis	0.127	0.873	0.000
M33 Dermatopolymyositis	0.127	0.873	0.000
M32 Systemic lupus erythematosus	0.127	0.873	0.000
M30 Polyarteritis nodosa and related conditions	0.127	0.873	0.000
M25.77 Osteophyte (Ankle and foot)	0.127	0.873	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.126	0.874	0.000
M53 Other dorsopathies, not elsewhere classified	0.126	0.874	0.000
M84 Disorders of continuity of bone	0.125	0.874	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.125	0.875	0.000
M23.5 Chronic instability of knee	0.125	0.875	0.000
M25.78 Osteophyte (Other)	0.125	0.875	0.000
M49 Spondylopathies in diseases classified elsewhere	0.124	0.875	0.000
M24 Other specific joint derangements	0.124	0.876	0.000
M19.0 Primary arthrosis of other joints	0.124	0.876	0.000
M54.3 Sciatica	0.124	0.876	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.123	0.876	0.000
M23.9 Internal derangement of knee, unspecified	0.122	0.878	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.122	0.878	0.000
M23.1 Discoid meniscus (congenital)	0.122	0.878	0.000
M23.0 Cystic meniscus	0.122	0.878	0.000
M47.82 Other spondylosis (Cervical region)	0.121	0.878	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.121	0.879	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.121	0.879	0.000
M51.8 Other specified intervertebral disk disorders	0.121	0.879	0.000
M25.8 Other specified joint disorders	0.121	0.879	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.121	0.879	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.121	0.879	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.121	0.879	0.000
M22 Disorders of patella	0.121	0.879	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.120	0.880	0.000
M66 Spontaneous rupture of synovium and tendon	0.120	0.880	0.000
M54.9 Dorsalgia, unspecified	0.120	0.880	0.000
M47.1 Other spondylosis with myelopathy	0.119	0.880	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.119	0.880	0.000
M50.3 Other cervical disk degeneration	0.119	0.881	0.000
M45 Ankylosing spondylitis	0.118	0.882	0.000
M51.9 Intervertebral disk disorder, unspecified	0.118	0.882	0.000
M20.4 Other hammer toe(s) (acquired)	0.116	0.884	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.116	0.884	0.000
M20.2 Hallux rigidus	0.116	0.884	0.000
M41 Scoliosis	0.115	0.885	0.000
M21.0 Valgus deformity, not elsewhere classified	0.115	0.885	0.000
M18 Arthrosis of first carpometacarpal joint	0.114	0.886	0.000
M43 Other deforming dorsopathies	0.114	0.886	0.000
M00 Pyogenic arthritis	0.113	0.886	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.113	0.887	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.113	0.887	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.113	0.887	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.113	0.887	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.112	0.887	0.000
M23.37 Other meniscus derangements-Capsular lig	0.112	0.887	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.112	0.887	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.112	0.887	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.112	0.887	0.000
M50.9 Cervical disk disorder, unspecified	0.112	0.887	0.000
M50.8 Other cervical disk disorders	0.112	0.887	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.112	0.888	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.112	0.888	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.111	0.889	0.000
M25.9 Joint disorder, unspecified	0.111	0.889	0.000
M25.3 Other instability of joint	0.111	0.889	0.000
M25.2 Flail joint	0.111	0.889	0.000
M25.1 Fistula of joint	0.111	0.889	0.000
M25.0 Haemarthrosis	0.111	0.889	0.000
M50.0 Cervical disk disorder with myelopathy	0.110	0.889	0.000
M54.8 Other dorsalgia	0.110	0.890	0.000
M54.6 Pain in thoracic spine	0.110	0.890	0.000
M54.4 Lumbago with sciatica	0.110	0.890	0.000
M54.0 Panniculitis affecting regions of neck and back	0.110	0.890	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.109	0.890	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.109	0.891	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.109	0.891	0.000
M23.8 Other internal derangements of knee	0.109	0.891	0.000
M17 Gonarthrosis [arthrosis of knee]	0.108	0.892	0.000
M80 Osteoporosis with pathological fracture	0.108	0.892	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.107	0.893	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.107	0.893	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.107	0.893	0.000
M31.6 Other giant cell arteritis	0.107	0.893	0.000
M51.3 Other specified intervertebral disk degeneration	0.106	0.894	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.106	0.894	0.000
M51.4 Schmorl's nodes	0.106	0.894	0.000
M90 Osteopathies in diseases classified elsewhere	0.106	0.894	0.000
M15 Polyarthrosis	0.106	0.894	0.000
M42 Spinal osteochondrosis	0.105	0.895	0.000
M40 Kyphosis and lordosis	0.105	0.895	0.000
M19.9 Arthrosis, unspecified	0.105	0.895	0.000
M87 Osteonecrosis	0.105	0.895	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.105	0.895	0.000
M83 Adult osteomalacia	0.104	0.896	0.000
M82 Osteoporosis in diseases classified elsewhere	0.104	0.896	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.104	0.896	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.104	0.896	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.104	0.896	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.104	0.896	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.104	0.896	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.104	0.896	0.000
M70-M79 Other soft tissue disorders	0.104	0.896	0.000
M23.49 Loose body in knee-Unspec lig/men	0.103	0.897	0.000
M21.3 Wrist or foot drop (acquired)	0.103	0.897	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.103	0.897	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.103	0.897	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.103	0.897	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.103	0.897	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.103	0.897	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.103	0.897	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.103	0.897	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.103	0.897	0.000
M54.39 Sciatica (Site unspecified)	0.103	0.897	0.000
M54.1 Radiculopathy	0.103	0.897	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.103	0.897	0.000
M25.79 Osteophyte (Site unspecified)	0.103	0.897	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.103	0.897	0.000
M25.73 Osteophyte (Forearm)	0.103	0.897	0.000
M25.72 Osteophyte (Upper arm)	0.103	0.897	0.000
M25.71 Osteophyte (Shoulder region)	0.103	0.897	0.000
M25.70 Osteophyte (Multiple sites)	0.103	0.897	0.000
M67 Other disorders of synovium and tendon	0.102	0.897	0.000
M47.89 Other spondylosis (Site unspecified)	0.102	0.898	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.102	0.898	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.102	0.898	0.000
M47.84 Other spondylosis (Thoracic region)	0.102	0.898	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.102	0.898	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.102	0.898	0.000
M85 Other disorders of bone density and structure	0.102	0.898	0.000
M25.76 Osteophyte (Lower leg)	0.102	0.898	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.102	0.898	0.000
M02 Reactive arthropathies	0.102	0.898	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.102	0.898	0.000
M21.9 Acquired deformity of limb, unspecified	0.101	0.899	0.000
M21.8 Other specified acquired deformities of limbs	0.101	0.899	0.000
M21.7 Unequal limb length (acquired)	0.101	0.899	0.000
M21.6 Other acquired deformities of ankle and foot	0.101	0.899	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.101	0.899	0.000
M21.4 Flat foot [pes planus] (acquired)	0.101	0.899	0.000
M21.2 Flexion deformity	0.101	0.899	0.000
M21.1 Varus deformity, not elsewhere classified	0.101	0.899	0.000
M19.1 Posttraumatic arthrosis of other joints	0.101	0.899	0.000
M86 Osteomyelitis	0.100	0.900	0.000
M20.3 Other deformity of hallux (acquired)	0.100	0.900	0.000
M88 Paget's disease of bone [osteitis deformans]	0.099	0.900	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.100	0.900	0.000
M46.8 Other specified inflammatory spondylopathies	0.099	0.901	0.000
M46.5 Other infective spondylopathies	0.099	0.901	0.000
M46.4 Discitis, unspecified	0.099	0.901	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.099	0.901	0.000
M46.2 Osteomyelitis of vertebra	0.099	0.901	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.099	0.901	0.000
M46.0 Spinal enthesopathy	0.099	0.901	0.000
M89 Other disorders of bone	0.098	0.902	0.000
M65.8 Other synovitis and tenosynovitis	0.098	0.902	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.098	0.902	0.000
M65.2 Calcific tendinitis	0.098	0.902	0.000
M65.1 Other infective (teno)synovitis	0.098	0.902	0.000
M65.0 Abscess of tendon sheath	0.098	0.902	0.000
M31.9 Necrotising vasculopathy, unspecified	0.098	0.902	0.000
M31.8 Other specified necrotising vasculopathies	0.098	0.902	0.000
M31.7 Microscopic polyangiitis	0.098	0.902	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.098	0.902	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.098	0.902	0.000
M31.3 Wegener's granulomatosis	0.098	0.902	0.000
M31.2 Lethal midline granuloma	0.098	0.902	0.000
M31.1 Thrombotic microangiopathy	0.098	0.902	0.000
M31.0 Hypersensitivity angiitis	0.098	0.902	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.098	0.902	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.097	0.902	0.000
M19.8 Other specified arthrosis	0.097	0.903	0.000
M19.2 Other secondary arthrosis	0.097	0.903	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.097	0.903	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.097	0.903	0.000
M54.55 Low back pain (Thoracolumbar region)	0.097	0.903	0.000
M54.54 Low back pain-Thoracic	0.097	0.903	0.000
M54.53 Low back pain-Cervicothoracic	0.097	0.903	0.000
M54.52 Low back pain-Cervical	0.097	0.903	0.000
M54.51 Low back pain-Occipit-atl-axl	0.097	0.903	0.000
M54.50 Low back pain (Multiple sites in spine)	0.097	0.903	0.000
M51.2 Other specified intervertebral disk displacement	0.097	0.903	0.000
M65.3 Trigger finger	0.096	0.904	0.000
M25.74 Osteophyte (Hand)	0.095	0.905	0.000
M17.9 Gonarthrosis, unspecified	0.095	0.905	0.000
M66.0 Rupture of popliteal cyst	0.095	0.905	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.095	0.905	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.094	0.905	0.000
M23.47 Loose body in knee-Capsular lig	0.094	0.906	0.000
M23.46 Loose body in knee-O/unsp lat men	0.094	0.906	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.094	0.906	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.094	0.906	0.000
M23.43 Loose body in knee-Med lig/oth men	0.094	0.906	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.094	0.906	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.094	0.906	0.000
M23.40 Loose body in knee-Mult sites	0.094	0.906	0.000
M20.0 Deformity of finger(s)	0.094	0.906	0.000
M54.2 Cervicalgia	0.093	0.906	0.000
M00.9 Pyogenic arthritis, unspecified	0.093	0.906	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.093	0.906	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.093	0.907	0.000
M62 Other disorders of muscle	0.093	0.907	0.000
M61 Calcification and ossification of muscle	0.093	0.907	0.000
M60 Myositis	0.093	0.907	0.000
M94 Other disorders of cartilage	0.093	0.907	0.000
M93 Other osteochondropathies	0.093	0.907	0.000
M92 Other juvenile osteochondrosis	0.093	0.907	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.093	0.907	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.093	0.907	0.000
M48.9 Spondylopathy, unspecified	0.093	0.907	0.000
M48.8 Other specified spondylopathies	0.093	0.907	0.000
M48.4 Fatigue fracture of vertebra	0.093	0.907	0.000
M48.3 Traumatic spondylopathy	0.093	0.907	0.000
M48.2 Kissing spine	0.093	0.907	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.093	0.907	0.000
M25.5 Pain in joint	0.093	0.907	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.093	0.907	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.092	0.908	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.092	0.908	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.092	0.908	0.000
M41.9 Scoliosis, unspecified	0.092	0.908	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.092	0.908	0.000
M54.57 Low back pain (Lumbosacral region)	0.091	0.909	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.091	0.909	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.091	0.909	0.000
M30.2 Juvenile polyarteritis	0.091	0.909	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.091	0.909	0.000
M30.0 Polyarteritis nodosa	0.091	0.909	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.091	0.909	0.000
M32.8 Other forms of systemic lupus erythematosus	0.091	0.909	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.091	0.909	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.091	0.909	0.000
M33.9 Dermatopolymyositis, unspecified	0.091	0.909	0.000
M33.2 Polymyositis	0.091	0.909	0.000
M33.1 Other dermatomyositis	0.091	0.909	0.000
M33.0 Juvenile dermatomyositis	0.091	0.909	0.000
M34.9 Systemic sclerosis, unspecified	0.091	0.909	0.000
M34.8 Other forms of systemic sclerosis	0.091	0.909	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.091	0.909	0.000
M34.1 CR(E)ST syndrome	0.091	0.909	0.000
M34.0 Progressive systemic sclerosis	0.091	0.909	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.091	0.909	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.091	0.909	0.000
M36.3 Arthropathy in other blood disorders	0.091	0.909	0.000
M36.2 Haemophilic arthropathy	0.091	0.909	0.000
M36.1 Arthropathy in neoplastic disease	0.091	0.909	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.091	0.909	0.000
M81 Osteoporosis without pathological fracture	0.091	0.909	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.091	0.909	0.000
M99 Biomechanical lesions, not elsewhere classified	0.091	0.909	0.000
M43.1 Spondylolisthesis	0.091	0.909	0.000
M53.9 Dorsopathy, unspecified	0.090	0.910	0.000
M53.8 Other specified dorsopathies	0.090	0.910	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.090	0.910	0.000
M53.2 Spinal instabilities	0.090	0.910	0.000
M53.1 Cervicobrachial syndrome	0.090	0.910	0.000
M53.0 Cervicocranial syndrome	0.090	0.910	0.000
M84.9 Disorder of continuity of bone, unspecified	0.090	0.910	0.000
M84.8 Other disorders of continuity of bone	0.090	0.910	0.000
M84.4 Pathological fracture, not elsewhere classified	0.090	0.910	0.000
M84.3 Stress fracture, not elsewhere classified	0.090	0.910	0.000
M84.2 Delayed union of fracture	0.090	0.910	0.000
M84.0 Malunion of fracture	0.090	0.910	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.090	0.910	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.090	0.910	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.090	0.910	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.090	0.910	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.090	0.910	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.090	0.910	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.090	0.910	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.090	0.910	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.090	0.910	0.000
M25.84 Other specified joint disorders (Hand)	0.090	0.910	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.090	0.910	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.090	0.910	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.089	0.910	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.089	0.910	0.000
M49.4 Neuropathic spondylopathy	0.089	0.910	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.089	0.910	0.000
M49.2 Enterobacterial spondylitis	0.089	0.910	0.000
M49.1 Brucella spondylitis	0.089	0.910	0.000
M49.0 Tuberculosis of spine	0.089	0.910	0.000
M24.9 Joint derangement, unspecified	0.089	0.910	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.089	0.910	0.000
M24.7 Protrusio acetabuli	0.089	0.910	0.000
M24.6 Ankylosis of joint	0.089	0.910	0.000
M24.5 Contracture of joint	0.089	0.910	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.089	0.910	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.089	0.910	0.000
M24.2 Disorder of ligament	0.089	0.910	0.000
M24.0 Loose body in joint	0.089	0.910	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.089	0.911	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.089	0.911	0.000
M19.08 Primary arthrosis of other joints (Other)	0.089	0.911	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.089	0.911	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.089	0.911	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.089	0.911	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.089	0.911	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.089	0.911	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.089	0.911	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.089	0.911	0.000
M54.37 Sciatica (Lumbosacral region)	0.089	0.911	0.000
M54.36 Sciatica (Lumbar region)	0.089	0.911	0.000
M54.35 Sciatica (Thoracolumbar region)	0.089	0.911	0.000
M54.34 Sciatica-Thoracic	0.089	0.911	0.000
M54.33 Sciatica-Cervicothoracic	0.089	0.911	0.000
M54.32 Sciatica-Cervical	0.089	0.911	0.000
M54.31 Sciatica-Occipit-atl-axl	0.089	0.911	0.000
M54.30 Sciatica (Multiple sites in spine)	0.089	0.911	0.000
M22.8 Other disorders of patella	0.089	0.911	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.089	0.911	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.089	0.911	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.089	0.911	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.089	0.911	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.089	0.911	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.089	0.911	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.088	0.912	0.000
M25.4 Effusion of joint	0.088	0.912	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.087	0.912	0.000
M23.07 Cystic meniscus-Capsular lig	0.087	0.912	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.087	0.912	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.087	0.912	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.087	0.912	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.087	0.912	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.087	0.912	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.087	0.912	0.000
M23.00 Cystic meniscus (Multiple sites)	0.087	0.912	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.087	0.912	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.087	0.912	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.087	0.912	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.087	0.912	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.087	0.912	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.087	0.912	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.087	0.912	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.087	0.912	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.087	0.912	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.087	0.912	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.087	0.912	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.087	0.912	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.087	0.912	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.087	0.912	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.087	0.912	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.087	0.912	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.087	0.912	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.087	0.912	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.087	0.912	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.087	0.912	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.087	0.912	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.087	0.912	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.087	0.912	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.087	0.912	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.087	0.912	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.087	0.912	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.087	0.912	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.087	0.912	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.087	0.912	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.087	0.913	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.087	0.913	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.087	0.913	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.087	0.913	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.087	0.913	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.087	0.913	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.087	0.913	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.087	0.913	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.087	0.913	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.087	0.913	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.087	0.913	0.000
M25.88 Other specified joint disorders (Other)	0.087	0.913	0.000
M25.86 Other specified joint disorders (Lower leg)	0.087	0.913	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.087	0.913	0.000
M25.83 Other specified joint disorders (Forearm)	0.087	0.913	0.000
M25.82 Other specified joint disorders (Upper arm)	0.087	0.913	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.087	0.913	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.087	0.913	0.000
M24.1 Other articular cartilage disorders	0.087	0.913	0.000
M22.1 Recurrent subluxation of patella	0.087	0.913	0.000
M22.9 Disorder of patella, unspecified	0.087	0.913	0.000
M22.3 Other derangements of patella	0.087	0.913	0.000
M22.2 Patellofemoral disorders	0.087	0.913	0.000
M22.0 Recurrent dislocation of patella	0.087	0.913	0.000
M05-M14 Inflammatory polyarthropathies	0.086	0.914	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.086	0.914	0.000
M66.4 Spontaneous rupture of other tendons	0.086	0.914	0.000
M66.3 Spontaneous rupture of flexor tendons	0.086	0.914	0.000
M66.2 Spontaneous rupture of extensor tendons	0.086	0.914	0.000
M66.1 Rupture of synovium	0.086	0.914	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.086	0.914	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.086	0.914	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.086	0.914	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.086	0.914	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.086	0.914	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.086	0.914	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.086	0.914	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.086	0.914	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.086	0.914	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.086	0.914	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.086	0.914	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.086	0.914	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.086	0.914	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.086	0.914	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.086	0.914	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.086	0.914	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.086	0.914	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.086	0.914	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.086	0.914	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.086	0.914	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.086	0.914	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.086	0.914	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.086	0.914	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.086	0.914	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.086	0.914	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.086	0.914	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.086	0.914	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.086	0.914	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.086	0.914	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.086	0.914	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.085	0.915	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.085	0.915	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.085	0.915	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.085	0.915	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.085	0.915	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.085	0.915	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations