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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs684513
log Bayes Factor = 14.0992
Chromosome 15   position 78,858,400  (GRCh37) Explore rs684513 on Ensembl!
Variant rs684513 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.001 0.999
I71 Aortic aneurysm and dissection
0.000 0.001 0.999
I73 Other peripheral vascular diseases
0.000 0.002 0.998
J43.9 Emphysema, unspecified
0.000 0.003 0.997
J40-J47 Chronic lower respiratory diseases
0.000 0.003 0.997
J43 Emphysema
0.000 0.003 0.997
I73.9 Peripheral vascular disease, unspecified
0.000 0.003 0.997
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.005 0.995
I70 Atherosclerosis
0.000 0.006 0.994
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.006 0.994
I60-I69 Cerebrovascular diseases
0.000 0.009 0.991
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.010 0.990
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.013 0.987
Chapter IX Diseases of the circulatory system
0.000 0.015 0.985
I60 Subarachnoid haemorrhage
0.000 0.021 0.979
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.023 0.977
I67 Other cerebrovascular diseases
0.000 0.026 0.974
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.033 0.967
I77 Other disorders of arteries and arterioles
0.000 0.039 0.961
I67.9 Cerebrovascular disease, unspecified
0.000 0.050 0.950
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.054 0.946
I69 Sequelae of cerebrovascular disease
0.000 0.065 0.935
J42 Unspecified chronic bronchitis
0.000 0.079 0.921
I26 Pulmonary embolism
0.000 0.093 0.907
I27 Other pulmonary heart diseases
0.000 0.097 0.903
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.113 0.887
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.114 0.886
I77.1 Stricture of artery
0.000 0.114 0.886
I27.9 Pulmonary heart disease, unspecified
0.000 0.118 0.882
I73.0 Raynaud's syndrome
0.000 0.123 0.877
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.131 0.869
I77.0 Arteriovenous fistula, acquired
0.000 0.135 0.865
I72 Other aneurysm
0.000 0.140 0.860
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.141 0.859
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.153 0.847
I67.1 Cerebral aneurysm, nonruptured
0.000 0.155 0.845
I60.8 Other subarachnoid haemorrhage
0.000 0.157 0.843
Chapter X Diseases of the respiratory system
0.000 0.158 0.842
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.159 0.841
J90-J94 Other diseases of pleura
0.000 0.164 0.836
J92 Pleural plaque
0.000 0.169 0.831
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.175 0.825
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.175 0.825
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.178 0.822
I67.8 Other specified cerebrovascular diseases
0.000 0.183 0.817
J60-J70 Lung diseases due to external agents
0.000 0.191 0.809
J92.0 Pleural plaque with presence of asbestos
0.000 0.194 0.806
I69.3 Sequelae of cerebral infarction
0.000 0.207 0.793
J92.9 Pleural plaque without asbestos
0.000 0.208 0.792
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.212 0.788
J43.2 Centrilobular emphysema
0.000 0.212 0.788
I70.0 Atherosclerosis of aorta
0.000 0.217 0.783
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.228 0.772
J90 Pleural effusion, not elsewhere classified
0.000 0.239 0.761
I72.0 Aneurysm of carotid artery
0.000 0.242 0.758
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.243 0.757
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.251 0.749
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.253 0.747
I77.2 Rupture of artery
0.000 0.255 0.745
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.256 0.744
I71.0 Dissection of aorta [any part]
0.000 0.256 0.744
I72.8 Aneurysm of other specified arteries
0.000 0.268 0.732
I78 Diseases of capillaries
0.000 0.274 0.726
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.275 0.725
J95-J99 Other diseases of the respiratory system
0.000 0.279 0.721
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.716
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.716
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.716
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.716
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.284 0.716
I28 Other diseases of pulmonary vessels
0.000 0.284 0.716
J41 Simple and mucopurulent chronic bronchitis
0.000 0.285 0.715
J43.1 Panlobular emphysema
0.000 0.285 0.715
J43.0 MacLeod's syndrome
0.000 0.285 0.715
I70.9 Generalised and unspecified atherosclerosis
0.000 0.287 0.713
I70.8 Atherosclerosis of other arteries
0.000 0.287 0.713
I61 Intracerebral haemorrhage
0.000 0.297 0.703
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.298 0.702
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.298 0.702
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.302 0.698
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.302 0.698
I67.5 Moyamoya disease
0.000 0.302 0.698
I67.4 Hypertensive encephalopathy
0.000 0.302 0.698
I67.3 Progressive vascular leukoencephalopathy
0.000 0.302 0.698
I00-I02 Acute rheumatic fever
0.000 0.302 0.698
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.302 0.697
I27.8 Other specified pulmonary heart diseases
0.000 0.303 0.697
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.305 0.695
I77.5 Necrosis of artery
0.000 0.311 0.689
I77.4 Coeliac artery compression syndrome
0.000 0.311 0.689
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.325 0.674
I72.9 Aneurysm of unspecified site
0.000 0.327 0.673
J86 Pyothorax
0.000 0.341 0.659
I70.1 Atherosclerosis of renal artery
0.000 0.346 0.654
J98 Other respiratory disorders
0.000 0.349 0.651
I27.1 Kyphoscoliotic heart disease
0.000 0.352 0.648
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.353 0.647
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.354 0.646
I73.8 Other specified peripheral vascular diseases
0.000 0.360 0.639
J60 Coalworker's pneumoconiosis
0.000 0.366 0.634
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.368 0.632
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.372 0.628
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.375 0.625
I74 Arterial embolism and thrombosis
0.000 0.378 0.622
J86.9 Pyothorax without fistula
0.000 0.380 0.620
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.382 0.617
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.383 0.617
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.383 0.617
I72.1 Aneurysm of artery of upper extremity
0.000 0.383 0.617
J98.1 Pulmonary collapse
0.000 0.385 0.615
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.394 0.606
J64 Unspecified pneumoconiosis
0.000 0.403 0.597
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.410 0.590
I79.1 Aortitis in diseases classified elsewhere
0.000 0.410 0.590
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.410 0.590
J93 Pneumothorax
0.000 0.411 0.589
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.411 0.589
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.420 0.580
J66 Airway disease due to specific organic dust
0.000 0.420 0.580
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.420 0.580
J62 Pneumoconiosis due to dust containing silica
0.000 0.420 0.580
J65 Pneumoconiosis associated with tuberculosis
0.000 0.420 0.580
I67.2 Cerebral atherosclerosis
0.000 0.421 0.579
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.424 0.576
I72.3 Aneurysm of iliac artery
0.000 0.427 0.573
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.429 0.571
J43.8 Other emphysema
0.000 0.432 0.568
I68.0 Cerebral amyloid angiopathy
0.000 0.432 0.568
I77.8 Other specified disorders of arteries and arterioles
0.000 0.433 0.567
I77.3 Arterial fibromuscular dysplasia
0.000 0.436 0.564
I77.6 Arteritis, unspecified
0.000 0.436 0.564
J70 Respiratory conditions due to other external agents
0.000 0.438 0.562
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.438 0.562
J98.9 Respiratory disorder, unspecified
0.000 0.446 0.554
J69 Pneumonitis due to solids and liquids
0.000 0.460 0.540
I28.8 Other specified diseases of pulmonary vessels
0.000 0.464 0.535
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.466 0.534
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.466 0.534
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.466 0.534
J93.1 Other spontaneous pneumothorax
0.000 0.476 0.524
I78.9 Disease of capillaries, unspecified
0.000 0.479 0.521
J98.4 Other disorders of lung
0.000 0.480 0.520
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.481 0.519
J96 Respiratory failure, not elsewhere classified
0.000 0.483 0.517
I72.2 Aneurysm of renal artery
0.000 0.483 0.517
I62 Other nontraumatic intracranial haemorrhage
0.000 0.483 0.517
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.487 0.513
I28.1 Aneurysm of pulmonary artery
0.000 0.487 0.513
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.487 0.513
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.487 0.512
J41.1 Mucopurulent chronic bronchitis
0.000 0.487 0.512
J41.0 Simple chronic bronchitis
0.000 0.487 0.512
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.489 0.511
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.489 0.511
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.489 0.511
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.489 0.511
I72.4 Aneurysm of artery of lower extremity
0.000 0.490 0.510
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.493 0.507
I02 Rheumatic chorea
0.000 0.499 0.500
I01 Rheumatic fever with heart involvement
0.000 0.499 0.500
I27.2 Other secondary pulmonary hypertension
0.000 0.503 0.497
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.503 0.497
I00 Rheumatic fever without mention of heart involvement
0.000 0.507 0.492
J46 Status asthmaticus
0.000 0.507 0.492
I05-I09 Chronic rheumatic heart diseases
0.000 0.508 0.492
I78.8 Other diseases of capillaries
0.000 0.511 0.489
J98.2 Interstitial emphysema
0.000 0.511 0.489
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.512 0.487
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.516 0.483
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.516 0.483
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.516 0.483
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.516 0.483
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.516 0.483
J91 Pleural effusion in conditions classified elsewhere
0.000 0.518 0.482
I27.0 Primary pulmonary hypertension
0.000 0.518 0.482
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.526 0.474
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.526 0.474
I78.1 Naevus, nonneoplastic
0.000 0.527 0.473
J94 Other pleural conditions
0.000 0.529 0.471
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.529 0.470
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.530 0.469
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.531 0.469
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.533 0.467
J98.3 Compensatory emphysema
0.000 0.533 0.467
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.534 0.466
J85 Abscess of lung and mediastinum
0.000 0.536 0.464
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.537 0.462
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.540 0.460
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.544 0.456
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.547 0.453
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.551 0.448
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.552 0.448
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.554 0.446
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.556 0.443
J86.0 Pyothorax with fistula
0.000 0.563 0.436
J99.0 Rheumatoid lung disease
0.000 0.567 0.433
I74.8 Embolism and thrombosis of other arteries
0.000 0.572 0.428
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.584 0.416
J62.0 Pneumoconiosis due to talc dust
0.000 0.584 0.416
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.584 0.416
J63.5 Stannosis
0.000 0.584 0.416
J63.4 Siderosis
0.000 0.584 0.416
J63.3 Graphite fibrosis (of lung)
0.000 0.584 0.416
J63.2 Berylliosis
0.000 0.584 0.416
J63.1 Bauxite fibrosis (of lung)
0.000 0.584 0.416
J63.0 Aluminosis (of lung)
0.000 0.584 0.416
J66.8 Airway disease due to other specific organic dusts
0.000 0.584 0.416
J66.2 Cannabinosis
0.000 0.584 0.416
J66.1 Flax-dresser's disease
0.000 0.584 0.416
J66.0 Byssinosis
0.000 0.584 0.416
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.584 0.416
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.584 0.416
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.584 0.416
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.584 0.416
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.584 0.416
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.584 0.416
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.584 0.416
I61.8 Other intracerebral haemorrhage
0.000 0.585 0.415
J69.8 Pneumonitis due to other solids and liquids
0.000 0.587 0.413
J93.0 Spontaneous tension pneumothorax
0.000 0.588 0.412
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.590 0.409
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.594 0.406
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.597 0.403
J70.8 Respiratory conditions due to other specified external agents
0.000 0.597 0.403
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.597 0.403
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.597 0.403
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.597 0.403
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.597 0.403
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.599 0.401
J98.6 Disorders of diaphragm
0.000 0.602 0.398
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.607 0.393
I09 Other rheumatic heart diseases
0.000 0.609 0.390
J69.1 Pneumonitis due to oils and essences
0.000 0.612 0.388
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.615 0.385
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.616 0.384
I05 Rheumatic mitral valve diseases
0.000 0.626 0.374
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.628 0.372
J67.7 Air-conditioner and humidifier lung
0.000 0.628 0.372
J67.6 Maple-bark-stripper's lung
0.000 0.628 0.372
J67.5 Mushroom-worker's lung
0.000 0.628 0.372
J67.4 Maltworker's lung
0.000 0.628 0.372
J67.3 Suberosis
0.000 0.628 0.372
J67.1 Bagassosis
0.000 0.628 0.372
J67.0 Farmer's lung
0.000 0.628 0.372
J96.9 Respiratory failure, unspecified
0.000 0.629 0.371
J96.1 Chronic respiratory failure
0.000 0.629 0.371
J96.0 Acute respiratory failure
0.000 0.629 0.371
J93.8 Other pneumothorax
0.000 0.635 0.365
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.641 0.359
I01.8 Other acute rheumatic heart disease
0.000 0.641 0.359
I01.2 Acute rheumatic myocarditis
0.000 0.641 0.359
I01.1 Acute rheumatic endocarditis
0.000 0.641 0.359
I01.0 Acute rheumatic pericarditis
0.000 0.641 0.359
I02.9 Rheumatic chorea without heart involvement
0.000 0.641 0.359
I02.0 Rheumatic chorea with heart involvement
0.000 0.641 0.359
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.641 0.359
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.641 0.359
I74.5 Embolism and thrombosis of iliac artery
0.000 0.648 0.352
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.648 0.352
J94.8 Other specified pleural conditions
0.000 0.649 0.350
J40 Bronchitis, not specified as acute or chronic
0.000 0.651 0.349
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.651 0.349
I62.1 Nontraumatic extradural haemorrhage
0.000 0.654 0.346
I07 Rheumatic tricuspid valve diseases
0.000 0.657 0.343
J85.1 Abscess of lung with pneumonia
0.000 0.658 0.342
J67.2 Bird fancier's lung
0.000 0.660 0.339
J94.9 Pleural condition, unspecified
0.000 0.662 0.338
J94.0 Chylous effusion
0.000 0.662 0.338
J98.8 Other specified respiratory disorders
0.000 0.665 0.335
I06 Rheumatic aortic valve diseases
0.000 0.667 0.333
J85.3 Abscess of mediastinum
0.000 0.667 0.332
J85.0 Gangrene and necrosis of lung
0.000 0.667 0.332
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.673 0.327
I09.9 Rheumatic heart disease, unspecified
0.000 0.682 0.318
I05.1 Rheumatic mitral insufficiency
0.000 0.683 0.317
J94.1 Fibrothorax
0.000 0.683 0.317
J20-J22 Other acute lower respiratory infections
0.000 0.683 0.317
I99 Other and unspecified disorders of circulatory system
0.000 0.684 0.316
J69.0 Pneumonitis due to food and vomit
0.000 0.690 0.310
I95 Hypotension
0.000 0.691 0.309
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.698 0.302
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.708 0.292
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.709 0.291
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.709 0.291
I95.1 Orthostatic hypotension
0.000 0.710 0.290
I05.0 Mitral stenosis
0.000 0.715 0.285
J45 Asthma
0.000 0.719 0.281
I09.8 Other specified rheumatic heart diseases
0.000 0.720 0.280
I09.2 Chronic rheumatic pericarditis
0.000 0.720 0.280
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.720 0.280
I09.0 Rheumatic myocarditis
0.000 0.720 0.280
J95.5 Postprocedural subglottic stenosis
0.000 0.725 0.275
J95.4 Mendelson's syndrome
0.000 0.725 0.275
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.725 0.275
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.725 0.275
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.725 0.275
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.725 0.275
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.728 0.271
J93.9 Pneumothorax, unspecified
0.000 0.731 0.269
I05.8 Other mitral valve diseases
0.000 0.731 0.268
J96.09 Acute respiratory failure; Type unspecified
0.000 0.734 0.266
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.734 0.266
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.734 0.266
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.734 0.266
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.734 0.266
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.734 0.266
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.734 0.266
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.734 0.266
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.734 0.266
J95.8 Other postprocedural respiratory disorders
0.000 0.737 0.263
J85.2 Abscess of lung without pneumonia
0.000 0.738 0.262
I05.2 Mitral stenosis with insufficiency
0.000 0.743 0.257
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.743 0.257
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.743 0.257
I98.0 Cardiovascular syphilis
0.000 0.743 0.257
I63 Cerebral infarction
0.000 0.744 0.256
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.749 0.251
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.749 0.251
I95.8 Other hypotension
0.000 0.751 0.249
I07.9 Tricuspid valve disease, unspecified
0.000 0.754 0.246
I07.8 Other tricuspid valve diseases
0.000 0.754 0.246
I07.2 Tricuspid stenosis with insufficiency
0.000 0.754 0.246
I07.0 Tricuspid stenosis
0.000 0.754 0.246
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.761 0.239
I06.8 Other rheumatic aortic valve diseases
0.000 0.761 0.239
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.761 0.239
I06.1 Rheumatic aortic insufficiency
0.000 0.761 0.239
I07.1 Tricuspid insufficiency
0.000 0.764 0.236
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.765 0.234
I97.0 Postcardiotomy syndrome
0.000 0.765 0.234
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.769 0.231
J95.0 Tracheostomy malfunction
0.000 0.771 0.229
I65.2 Occlusion and stenosis of carotid artery
0.000 0.777 0.223
J84 Other interstitial pulmonary diseases
0.000 0.779 0.221
J94.2 Haemothorax
0.001 0.780 0.220
I06.0 Rheumatic aortic stenosis
0.000 0.781 0.219
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.781 0.219
J21 Acute bronchiolitis
0.000 0.786 0.214
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.786 0.214
J20 Acute bronchitis
0.000 0.786 0.214
I65.1 Occlusion and stenosis of basilar artery
0.001 0.791 0.208
I05.9 Mitral valve disease, unspecified
0.000 0.794 0.205
J45.8 Mixed asthma
0.000 0.798 0.202
J45.1 Nonallergic asthma
0.000 0.798 0.202
J00-J06 Acute upper respiratory infections
0.000 0.800 0.200
I10-I15 Hypertensive diseases
0.000 0.802 0.198
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.803 0.197
I97.1 Other functional disturbances following cardiac surgery
0.000 0.807 0.192
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.811 0.189
J09-J18 Influenza and pneumonia
0.000 0.814 0.186
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.816 0.184
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.816 0.184
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.816 0.184
I95.0 Idiopathic hypotension
0.000 0.821 0.179
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.822 0.178
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.823 0.177
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.825 0.174
J84.8 Other specified interstitial pulmonary diseases
0.000 0.835 0.165
J84.0 Alveolar and parietoalveolar conditions
0.000 0.841 0.159
J20.8 Acute bronchitis due to other specified organisms
0.000 0.844 0.156
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.846 0.154
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.846 0.154
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.846 0.154
J20.7 Acute bronchitis due to echovirus
0.000 0.847 0.153
J20.6 Acute bronchitis due to rhinovirus
0.000 0.847 0.153
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.847 0.153
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.847 0.153
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.847 0.153
J20.2 Acute bronchitis due to streptococcus
0.000 0.847 0.153
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.847 0.153
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.847 0.153
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.847 0.152
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.852 0.148
I13 Hypertensive heart and renal disease
0.000 0.858 0.142
J00 Acute nasopharyngitis [common cold]
0.000 0.859 0.141
J21.9 Acute bronchiolitis, unspecified
0.000 0.859 0.140
I15 Secondary hypertension
0.000 0.861 0.139
C34.1 Upper lobe, bronchus or lung
0.000 0.861 0.139
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.862 0.138
J01 Acute sinusitis
0.000 0.863 0.137
J20.9 Acute bronchitis, unspecified
0.000 0.864 0.136
J45.0 Predominantly allergic asthma
0.000 0.864 0.136
C34 Malignant neoplasm of bronchus and lung
0.000 0.866 0.134
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.866 0.134
J09 Influenza due to certain identified influenza virus
0.000 0.866 0.134
C34.3 Lower lobe, bronchus or lung
0.000 0.870 0.130
C34.9 Bronchus or lung, unspecified
0.000 0.871 0.129
J17 Pneumonia in diseases classified elsewhere
0.000 0.871 0.129
J10 Influenza due to identified influenza virus
0.000 0.876 0.123
J12 Viral pneumonia, not elsewhere classified
0.000 0.878 0.122
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.879 0.121
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.884 0.115
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.888 0.112
J18 Pneumonia, organism unspecified
0.000 0.888 0.112
I15.1 Hypertension secondary to other renal disorders
0.000 0.889 0.111
J05.1 Acute epiglottitis
0.000 0.889 0.111
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.890 0.109
J04 Acute laryngitis and tracheitis
0.000 0.891 0.109
I12 Hypertensive renal disease
0.000 0.893 0.107
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.893 0.107
J05.0 Acute obstructive laryngitis [croup]
0.000 0.893 0.106
J01.0 Acute maxillary sinusitis
0.000 0.894 0.106
Z72.0 Tobacco use
0.000 0.894 0.106
J02 Acute pharyngitis
0.000 0.895 0.105
I11 Hypertensive heart disease
0.000 0.896 0.104
J03 Acute tonsillitis
0.000 0.896 0.104
J18.1 Lobar pneumonia, unspecified
0.000 0.897 0.103
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.898 0.102
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.898 0.102
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.898 0.102
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.898 0.102
I87 Other disorders of veins
0.000 0.898 0.102
Z72.1 Alcohol use
0.000 0.899 0.101
I15.9 Seconday hypertension, unspecified
0.000 0.899 0.101
Z72 Problems related to lifestyle
0.000 0.900 0.100
J14 Pneumonia due to Haemophilus influenzae
0.000 0.900 0.100
I15.8 Other secondary hypertension
0.000 0.900 0.100
I15.2 Hypertension secondary to endocrine disorders
0.000 0.900 0.100
E11 Non-insulin-dependent diabetes mellitus
0.000 0.901 0.099
J01.8 Other acute sinusitis
0.000 0.901 0.098
J01.4 Acute pansinusitis
0.000 0.901 0.098
J01.3 Acute sphenoidal sinusitis
0.000 0.901 0.098
J01.1 Acute frontal sinusitis
0.000 0.901 0.098
E11.3 With ophthalmic complications
0.000 0.902 0.098
F17.1 Harmful use
0.000 0.903 0.097
I85 Oesophageal varices
0.000 0.904 0.096
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.904 0.096
J16.0 Chlamydial pneumonia
0.000 0.904 0.096
I81 Portal vein thrombosis
0.000 0.905 0.095
I63.8 Other cerebral infarction
0.000 0.905 0.095
I88 Nonspecific lymphadenitis
0.000 0.906 0.094
I95.2 Hypotension due to drugs
0.000 0.906 0.093
J01.9 Acute sinusitis, unspecified
0.000 0.907 0.093
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.907 0.092
C34.2 Middle lobe, bronchus or lung
0.000 0.908 0.092
J11 Influenza, virus not identified
0.000 0.909 0.090
I87.1 Compression of vein
0.000 0.909 0.091
E11.5 With peripheral circulatory complications
0.000 0.910 0.090
E11.0 With coma
0.000 0.910 0.089
I80 Phlebitis and thrombophlebitis
0.000 0.911 0.089
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.911 0.089
J01.2 Acute ethmoidal sinusitis
0.000 0.911 0.088
E11.8 With unspecified complications
0.000 0.912 0.088
J12.8 Other viral pneumonia
0.000 0.912 0.087
J12.3 Human metapneumovirus pneumonia
0.000 0.912 0.087
J12.2 Parainfluenza virus pneumonia
0.000 0.912 0.087
J12.1 Respiratory syncytial virus pneumonia
0.000 0.912 0.087
J12.0 Adenoviral pneumonia
0.000 0.912 0.087
J15.2 Pneumonia due to staphylococcus
0.000 0.913 0.087
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.913 0.085
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.913 0.086
J81 Pulmonary oedema
0.001 0.914 0.086
I85.0 Oesophageal varices with bleeding
0.000 0.914 0.086
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.914 0.086
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.915 0.085
E11.1 With ketoacidosis
0.000 0.916 0.084
C34.8 Overlapping lesion of bronchus and lung
0.000 0.916 0.084
E11.2 With renal complications
0.000 0.917 0.083
E11.4 With neurological complications
0.000 0.917 0.083
J15.8 Other bacterial pneumonia
0.000 0.917 0.083
I87.8 Other specified disorders of veins
0.000 0.918 0.082
J15.5 Pneumonia due to Escherichia coli
0.000 0.918 0.081
I63.9 Cerebral infarction, unspecified
0.000 0.919 0.081
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.919 0.081
Z72.2 Drug use
0.000 0.919 0.081
J15.4 Pneumonia due to other streptococci
0.000 0.919 0.081
J18.2 Hypostatic pneumonia, unspecified
0.000 0.920 0.080
E11.6 With other specified complications
0.000 0.920 0.080
J15.9 Bacterial pneumonia, unspecified
0.000 0.920 0.079
J15.3 Pneumonia due to streptococcus, group B
0.000 0.921 0.079
J04.2 Acute laryngotracheitis
0.000 0.921 0.078
I15.0 Renovascular hypertension
0.000 0.922 0.078
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.922 0.078
J02.0 Streptococcal pharyngitis
0.000 0.922 0.077
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.923 0.077
I12.9 Hypertensive renal disease without renal failure
0.000 0.924 0.076
J17.3 Pneumonia in parasitic diseases
0.000 0.924 0.076
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.924 0.076
J12.9 Viral pneumonia, unspecified
0.000 0.924 0.075
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.925 0.075
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.925 0.074
J03.0 Streptococcal tonsillitis
0.000 0.925 0.074
J04.1 Acute tracheitis
0.000 0.926 0.074
I87.9 Disorder of vein, unspecified
0.000 0.927 0.073
I87.0 Postphlebitic syndrome
0.000 0.927 0.073
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.927 0.073
Z72.6 Gambling and betting
0.000 0.928 0.072
Z72.5 High-risk sexual behaviour
0.000 0.928 0.072
Z72.3 Lack of physical exercise
0.000 0.928 0.072
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.928 0.072
J18.8 Other pneumonia, organism unspecified
0.000 0.928 0.072
Z72.4 Inappropriate diet and eating habits
0.000 0.929 0.071
E11.7 With multiple complications
0.000 0.929 0.071
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.930 0.070
Z72.8 Other problems related to lifestyle
0.000 0.930 0.070
C34.0 Main bronchus
0.000 0.930 0.069
J06.0 Acute laryngopharyngitis
0.000 0.932 0.068

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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