TreeWAS – Variant ID: rs6845999

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.3 Sequelae of cerebral infarction	0.000	0.920	0.080
I69 Sequelae of cerebrovascular disease	0.000	0.935	0.065
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.937	0.063
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.947	0.053
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.949	0.051
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.951	0.049
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.983	0.017
D47.1 Chronic myeloproliferative disease	0.014	0.986	0.000
C50.8 Overlapping lesion of breast	0.010	0.990	0.000
G96.0 Cerebrospinal fluid leak	0.010	0.990	0.000
I85.9 Oesophageal varices without bleeding	0.010	0.990	0.000
S82.30 Fracture of lower end of tibia (closed)	0.009	0.991	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.008	0.992	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.008	0.992	0.000
I20.1 Angina pectoris with documented spasm	0.007	0.993	0.000
I85.0 Oesophageal varices with bleeding	0.007	0.993	0.000
I85 Oesophageal varices	0.007	0.993	0.000
Z13.1 Special screening examination for diabetes mellitus	0.006	0.994	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.006	0.994	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
O43.1 Malformation of placenta	0.000	0.994	0.006
D47.3 Essential (haemorrhagic) thrombocythaemia	0.006	0.994	0.000
F60.9 Personality disorder, unspecified	0.005	0.995	0.000
S92.00 Fracture of calcaneus (closed)	0.005	0.995	0.000
F60 Specific personality disorders	0.005	0.995	0.000
F60.3 Emotionally unstable personality disorder	0.005	0.995	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.004	0.996	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.004	0.996	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
D47.4 Osteomyelofibrosis	0.004	0.996	0.000
M20.4 Other hammer toe(s) (acquired)	0.004	0.996	0.000
F60.0 Paranoid personality disorder	0.004	0.996	0.000
F60.6 Anxious [avoidant] personality disorder	0.004	0.996	0.000
F60.4 Histrionic personality disorder	0.004	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
F60.7 Dependent personality disorder	0.004	0.996	0.000
F60.2 Dissocial personality disorder	0.003	0.996	0.000
F60.1 Schizoid personality disorder	0.003	0.996	0.000
G91.1 Obstructive hydrocephalus	0.004	0.996	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.996	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.004	0.996	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.004	0.996	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
F60.5 Anankastic personality disorder	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
Z82.3 Family history of stroke	0.003	0.997	0.000
G96 Other disorders of central nervous system	0.003	0.997	0.000
F60.8 Other specific personality disorders	0.003	0.997	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
L03.9 Cellulitis, unspecified	0.003	0.997	0.000
N05.9 Unspecified	0.000	0.997	0.003
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.997	0.003
I46.9 Cardiac arrest, unspecified	0.000	0.997	0.003
D47.2 Monoclonal gammopathy	0.003	0.997	0.000
G96.9 Disorder of central nervous system, unspecified	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
G91 Hydrocephalus	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.000	0.997	0.003
O43 Placental disorders	0.000	0.997	0.003
F60-F69 Disorders of adult personality and behaviour	0.003	0.997	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.997	0.003
G91.0 Communicating hydrocephalus	0.002	0.997	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.000	0.998	0.002
O43.8 Other placental disorders	0.000	0.998	0.002
G91.8 Other hydrocephalus	0.002	0.998	0.000
M79.19 Myalgia (Site unspecified)	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.000	0.998	0.002
E11.4 With neurological complications	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.002	0.998	0.000
F64 Gender identity disorders	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
F61 Mixed and other personality disorders	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N49.2 Inflammatory disorders of scrotum	0.002	0.998	0.000
F62.9 Enduring personality change, unspecified	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.000	0.998	0.002
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
B00.4 Herpesviral encephalitis	0.000	0.998	0.002
O43.9 Placental disorder, unspecified	0.000	0.998	0.002
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
J33.8 Other polyp of sinus	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
M70.4 Prepatellar bursitis	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
G25.3 Myoclonus	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.002	0.998	0.000
F64.0 Transsexualism	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.000	0.998	0.002
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.998	0.002
F62.8 Other enduring personality changes	0.002	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.002	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
F64.9 Gender identity disorder, unspecified	0.002	0.998	0.000
F64.8 Other gender identity disorders	0.002	0.998	0.000
F64.2 Gender identity disorder of childhood	0.002	0.998	0.000
F64.1 Dual-role transvestism	0.002	0.998	0.000
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
K09.2 Other cysts of jaw	0.000	0.998	0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
F63.9 Habit and impulse disorder, unspecified	0.002	0.998	0.000
F63.8 Other habit and impulse disorders	0.002	0.998	0.000
F63.3 Trichotillomania	0.002	0.998	0.000
F63.2 Pathological stealing [kleptomania]	0.002	0.998	0.000
F63.1 Pathological fire-setting [pyromania]	0.002	0.998	0.000
F63.0 Pathological gambling	0.002	0.998	0.000
F65.9 Disorder of sexual preference, unspecified	0.002	0.998	0.000
F65.8 Other disorders of sexual preference	0.002	0.998	0.000
F65.6 Multiple disorders of sexual preference	0.002	0.998	0.000
F65.5 Sadomasochism	0.002	0.998	0.000
F65.4 Paedophilia	0.002	0.998	0.000
F65.3 Voyeurism	0.002	0.998	0.000
F65.2 Exhibitionism	0.002	0.998	0.000
F65.1 Fetishistic transvestism	0.002	0.998	0.000
F65.0 Fetishism	0.002	0.998	0.000
F66.9 Psychosexual development disorder, unspecified	0.002	0.998	0.000
F66.8 Other psychosexual development disorders	0.002	0.998	0.000
F66.2 Sexual relationship disorder	0.002	0.998	0.000
F66.1 Egodystonic sexual orientation	0.002	0.998	0.000
F66.0 Sexual maturation disorder	0.002	0.998	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.002	0.998	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.002	0.998	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
G91.2 Normal-pressure hydrocephalus	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.001	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
Z82.1 Family history of blindness and visual loss	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.000	0.998	0.002
M70.49 Prepatellar bursitis-Site unspec	0.002	0.998	0.000
M70.48 Prepatellar bursitis-Other	0.002	0.998	0.000
M70.47 Prepatellar bursitis-Ankle/Foot	0.002	0.998	0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.002	0.998	0.000
M70.44 Prepatellar bursitis-Hand	0.002	0.998	0.000
M70.43 Prepatellar bursitis-Forearm	0.002	0.998	0.000
M70.42 Prepatellar bursitis-Upper arm	0.002	0.998	0.000
M70.41 Prepatellar bursitis-Shldr region	0.002	0.998	0.000
M70.40 Prepatellar bursitis-Mult sites	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
N05.6 Dense deposit disease	0.000	0.998	0.002
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N05.0 Minor glomerular abnormality	0.000	0.998	0.002
R44.1 Visual hallucinations	0.000	0.998	0.002
K25.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.000	0.998	0.002
D37.7 Other digestive organs	0.000	0.998	0.002
G94.1 Hydrocephalus in neoplastic disease	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.002	0.998	0.000
C44.1 Skin of eyelid, including canthus	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.002	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.001	0.998	0.000
Z13.5 Special screening examination for eye and ear disorders	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
N05.8 Other	0.000	0.998	0.002
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.998	0.002
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.998	0.002
B00.5 Herpesviral ocular disease	0.000	0.998	0.002
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.000	0.998	0.001
W29.9 Unspecified place	0.000	0.998	0.002
G94 Other disorders of brain in diseases classified elsewhere	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.001
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.998	0.001
S92.4 Fracture of great toe	0.001	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.001	0.998	0.000
B00.7 Disseminated herpesviral disease	0.000	0.998	0.001
B00.3 Herpesviral meningitis	0.000	0.998	0.001
N64.1 Fat necrosis of breast	0.000	0.998	0.002
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.998	0.002
Z82.2 Family history of deafness and hearing loss	0.001	0.998	0.000
K25.0 Acute with haemorrhage	0.001	0.998	0.000
R07.1 Chest pain on breathing	0.002	0.998	0.000
K09 Cysts of oral region, not elsewhere classified	0.000	0.998	0.001
K25.5 Chronic or unspecified with perforation	0.001	0.999	0.000
K61.1 Rectal abscess	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.001	0.999	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
T51.9 Alcohol, unspecified	0.000	0.999	0.001
S92.7 Multiple fractures of foot	0.001	0.999	0.000
Y88 Sequelae of surgical and medical care as external cause	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
B00.0 Eczema herpeticum	0.000	0.999	0.001
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
G94.2 Hydrocephalus in other diseases classified elsewhere	0.001	0.999	0.000
H60.4 Cholesteatoma of external ear	0.000	0.999	0.001
G90-G99 Other disorders of the nervous system	0.001	0.999	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.999	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.999	0.001
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
R40.1 Stupor	0.001	0.999	0.000
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
Z54.0 Convalescence following surgery	0.000	0.999	0.001
K70 Alcoholic liver disease	0.001	0.999	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
K09.9 Cyst of oral region, unspecified	0.000	0.999	0.001
S46.3 Injury of muscle and tendon of triceps	0.000	0.999	0.001
D62 Acute posthaemorrhagic anaemia	0.001	0.999	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.000	0.999	0.001
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.999	0.001
M15.99 Polyosteoarthritis, unspecified	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.999	0.001
N05.1 Focal and segmental glomerular lesions	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.999	0.001
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.001	0.999	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.999	0.001
G92 Toxic encephalopathy	0.001	0.999	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.999	0.001
S11.8 Open wound of other parts of neck	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.999	0.001
Y46.2 Hydantoin derivatives	0.000	0.999	0.001
Z52.8 Donor of other organs and tissues	0.001	0.999	0.000
K25 Gastric ulcer	0.001	0.999	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.999	0.001
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
K05.3 Chronic periodontitis	0.001	0.999	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.999	0.001
R25.3 Fasciculation	0.000	0.999	0.001
Z12.3 Special screening examination for neoplasm of breast	0.001	0.999	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.999	0.001
G25.2 Other specified forms of tremor	0.000	0.999	0.001
J38.3 Other diseases of vocal cords	0.001	0.999	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.999	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.999	0.000
D29.1 Prostate	0.000	0.999	0.001
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.999	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.999	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.999	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.999	0.001
Z12.9 Special screening examination for neoplasm, unspecified	0.001	0.999	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.001	0.999	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.999	0.001
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.999	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.999	0.001
M21.26 Flexion deformity (Lower leg)	0.001	0.999	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.999	0.001
S82.10 Fracture of upper end of tibia (closed)	0.000	0.999	0.001
B00.1 Herpesviral vesicular dermatitis	0.000	0.999	0.001
H60.0 Abscess of external ear	0.000	0.999	0.001
Z12.2 Special screening examination for neoplasm of respiratory organs	0.001	0.999	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.001	0.999	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.001	0.999	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.999	0.001
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.999	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.001	0.999	0.000
H60 Otitis externa	0.000	0.999	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.999	0.001
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.999	0.001
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.999	0.001
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.999	0.001
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.999	0.001
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.999	0.001
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.999	0.001
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.999	0.001
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
S82.11 Fracture of upper end of tibia (open)	0.000	0.999	0.001
K25.2 Acute with both haemorrhage and perforation	0.001	0.999	0.000
K25.1 Acute with perforation	0.001	0.999	0.000
S51.8 Open wound of other parts of forearm	0.001	0.999	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.999	0.001
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.999	0.000
Z12 Special screening examination for neoplasms	0.001	0.999	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.999	0.001
D56.3 Thalassaemia trait	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.001	0.999	0.000
M15.9 Polyarthrosis, unspecified	0.001	0.999	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.999	0.000
R40.0 Somnolence	0.001	0.999	0.000
S82.01 Fracture of patella (open)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.999	0.001
S49.8 Other specified injuries of shoulder and upper arm	0.001	0.999	0.000
Y89.9 Sequelae of unspecified external cause	0.000	0.999	0.001
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.001	0.999	0.000
O23 Infections of genito-urinary tract in pregnancy	0.001	0.999	0.000
Z13 Special screening examination for other diseases and disorders	0.001	0.999	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.001
F17.2 Dependence syndrome	0.000	0.999	0.001
F80.1 Expressive language disorder	0.001	0.999	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
X60.8 Other specified place	0.001	0.999	0.000
D41.2 Ureter	0.001	0.999	0.000
N32.3 Diverticulum of bladder	0.000	0.999	0.001
S31.1 Open wound of abdominal wall	0.001	0.999	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.999	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
G93.6 Cerebral oedema	0.001	0.999	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.001	0.999	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.001	0.999	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.999	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.999	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.999	0.001
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
Z13.8 Special screening examination for other specified diseases and disorders	0.001	0.999	0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
Z13.4 Special screening examination for certain developmental disorders in childhood	0.001	0.999	0.000
Z52.3 Bone marrow donor	0.001	0.999	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.999	0.001
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
M15.0 Primary generalised (osteo)arthrosis	0.001	0.999	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.001	0.999	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
S80.8 Other superficial injuries of lower leg	0.001	0.999	0.000
Z13.2 Special screening examination for nutritional disorders	0.001	0.999	0.000
Z52 Donors of organs and tissues	0.001	0.999	0.000
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
Z13.83 Encounter for screening for respiratory disorder NEC	0.001	0.999	0.000
Z13.82 Encounter for screening for musculoskeletal disorder	0.001	0.999	0.000
F80.2 Receptive language disorder	0.001	0.999	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.999	0.001
G97.1 Other reaction to spinal and lumbar puncture	0.001	0.999	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.999	0.001
N49.8 Inflammatory disorders of other specified male genital organs	0.001	0.999	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.999	0.001
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.999	0.001
M79.18 Myalgia (Other)	0.001	0.999	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.999	0.001
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.999	0.001
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.999	0.001
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.999	0.001
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.999	0.001
C71.1 Frontal lobe	0.000	0.999	0.001
D86.9 Sarcoidosis, unspecified	0.000	0.999	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.999	0.000
M15.1 Heberden's nodes (with arthropathy)	0.001	0.999	0.000
R74.8 Abnormal levels of other serum enzymes	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
Z52.9 Donor of unspecified organ or tissue	0.001	0.999	0.000
Z52.7 Heart donor	0.001	0.999	0.000
Z52.6 Liver donor	0.001	0.999	0.000
Z52.5 Cornea donor	0.001	0.999	0.000
Z52.1 Skin donor	0.001	0.999	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
D37.5 Rectum	0.001	0.999	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.001	0.999	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.999	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
H60.2 Malignant otitis externa	0.000	0.999	0.001
M15.8 Other polyarthrosis	0.001	0.999	0.000
M15.3 Secondary multiple arthrosis	0.001	0.999	0.000
Q24.5 Malformation of coronary vessels	0.001	0.999	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.999	0.001
Z52.0 Blood donor	0.001	0.999	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.999	0.001
S22.20 Fracture of sternum (closed)	0.000	0.999	0.001
T91.1 Sequelae of fracture of spine	0.000	0.999	0.001
Z12.6 Special screening examination for neoplasm of bladder	0.001	0.999	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
M15 Polyarthrosis	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
Z89.4 Acquired absence of foot and ankle	0.001	0.999	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
M21.27 Flexion deformity (Ankle and foot)	0.001	0.999	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
M70.04 Chronic crepitant synovitis of hand and wrist (Hand)	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.001	0.999	0.000
F51.5 Nightmares	0.001	0.999	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.999	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.001	0.999	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.999	0.001
N64.4 Mastodynia	0.000	0.999	0.001
N64.3 Galactorrhoea not associated with childbirth	0.000	0.999	0.001
R23.4 Changes in skin texture	0.000	0.999	0.001
Z49.0 Preparatory care for dialysis	0.000	0.999	0.001
M21.29 Flexion deformity (Site unspecified)	0.001	0.999	0.000
M21.28 Flexion deformity (Other)	0.001	0.999	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.999	0.000
M21.22 Flexion deformity (Upper arm)	0.001	0.999	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.999	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.999	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.999	0.001
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.999	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.999	0.001
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
F30.9 Manic episode, unspecified	0.001	0.999	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.001	0.999	0.000
F80.8 Other developmental disorders of speech and language	0.001	0.999	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.001	0.999	0.000
F80.0 Specific speech articulation disorder	0.001	0.999	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.001	0.999	0.000
K70.4 Alcoholic hepatic failure	0.001	0.999	0.000
K70.0 Alcoholic fatty liver	0.001	0.999	0.000
M21.2 Flexion deformity	0.001	0.999	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.001	0.999	0.000
F80 Specific developmental disorders of speech and language	0.001	0.999	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.999	0.001
E11.2 With renal complications	0.001	0.999	0.000
E11.1 With ketoacidosis	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.001	0.999	0.000
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
N64.0 Fissure and fistula of nipple	0.000	0.999	0.001
N64 Other disorders of breast	0.000	0.999	0.001
M25.34 Other instability of joint (Hand)	0.000	0.999	0.001
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
F07.0 Organic personality disorder	0.001	0.999	0.000
F50.9 Eating disorder, unspecified	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.999	0.001
G25.4 Drug-induced chorea	0.000	0.999	0.001
M15.4 Erosive (osteo)arthrosis	0.001	0.999	0.000
S82.1 Fracture of upper end of tibia	0.000	0.999	0.001
S89.8 Other specified injuries of lower leg	0.001	0.999	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.999	0.001
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.999	0.000
M70.09 Chronic crepitant synovitis of hand and wrist-Site unspec	0.001	0.999	0.000
M70.08 Chronic crepitant synovitis of hand and wrist-Other	0.001	0.999	0.000
M70.07 Chronic crepitant synovitis of hand and wrist-Ankle/Foot	0.001	0.999	0.000
M70.06 Chronic crepitant synovitis of hand and wrist-Lower Leg	0.001	0.999	0.000
M70.05 Chronic crepitant synovitis of hand and wrist-Pelvic/Thigh	0.001	0.999	0.000
M70.03 Chronic crepitant synovitis of hand and wrist (Forearm)	0.001	0.999	0.000
M70.02 Chronic crepitant synovitis of hand and wrist-Upper arm	0.001	0.999	0.000
M70.01 Chronic crepitant synovitis of hand and wrist-Shldr region	0.001	0.999	0.000
M70.00 Chronic crepitant synovitis of hand and wrist (Multiple sites)	0.001	0.999	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.001	0.999	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.999	0.000
S52.80 Fracture of other parts of forearm (closed)	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.1 Postencephalitic syndrome	0.001	0.999	0.000
H60.3 Other infective otitis externa	0.000	0.999	0.001
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.999	0.001
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.999	0.001
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations