TreeWAS – Variant ID: rs6855812

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44 Other chronic obstructive pulmonary disease	0.000	0.000	1.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.000	1.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.000	1.000
J43.9 Emphysema, unspecified	0.000	0.003	0.997
J43 Emphysema	0.000	0.007	0.993
J40-J47 Chronic lower respiratory diseases	0.000	0.012	0.988
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.033	0.967
J43.2 Centrilobular emphysema	0.000	0.191	0.809
J43.8 Other emphysema	0.000	0.248	0.752
J41 Simple and mucopurulent chronic bronchitis	0.000	0.281	0.719
J43.1 Panlobular emphysema	0.000	0.288	0.712
J43.0 MacLeod's syndrome	0.000	0.288	0.712
J42 Unspecified chronic bronchitis	0.000	0.314	0.686
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.315	0.685
J41.0 Simple chronic bronchitis	0.000	0.474	0.525
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.485	0.515
J41.1 Mucopurulent chronic bronchitis	0.000	0.485	0.515
J46 Status asthmaticus	0.000	0.490	0.510
J47 Bronchiectasis	0.000	0.546	0.454
J40 Bronchitis, not specified as acute or chronic	0.000	0.622	0.378
J45 Asthma	0.000	0.704	0.296
J45.8 Mixed asthma	0.000	0.801	0.199
J45.1 Nonallergic asthma	0.000	0.808	0.192
J45.9 Asthma, unspecified	0.000	0.825	0.175
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.942	0.058
J45.0 Predominantly allergic asthma	0.000	0.944	0.056
N86 Erosion and ectropion of cervix uteri	0.049	0.951	0.000
R27.0 Ataxia, unspecified	0.000	0.980	0.020
I69.3 Sequelae of cerebral infarction	0.000	0.982	0.018
R27 Other lack of coordination	0.000	0.983	0.017
I69 Sequelae of cerebrovascular disease	0.000	0.983	0.017
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.983	0.017
R29.6 Tendency to fall, not elsewhere classified	0.000	0.983	0.017
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.015	0.985	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.985	0.015
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.985	0.015
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.985	0.015
R27.8 Other and unspecified lack of coordination	0.000	0.986	0.014
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.986	0.014
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.986	0.014
R26 Abnormalities of gait and mobility	0.000	0.987	0.013
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.987	0.013
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.988	0.012
R26.0 Ataxic gait	0.000	0.989	0.011
R29.4 Clicking hip	0.000	0.989	0.011
R29.3 Abnormal posture	0.000	0.989	0.011
R29.0 Tetany	0.000	0.989	0.011
H33.3 Retinal breaks without detachment	0.000	0.989	0.011
R29.1 Meningismus	0.000	0.989	0.010
N61 Inflammatory disorders of breast	0.000	0.990	0.010
R29.2 Abnormal reflex	0.000	0.990	0.010
R26.1 Paralytic gait	0.000	0.990	0.010
M54.16 Radiculopathy (Lumbar region)	0.000	0.990	0.010
J38.4 Oedema of larynx	0.010	0.990	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.990	0.010
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.990	0.010
G81.9 Hemiplegia, unspecified	0.000	0.992	0.008
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.008	0.992	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.993	0.007
I35.1 Aortic (valve) insufficiency	0.000	0.993	0.007
K86.9 Disease of pancreas, unspecified	0.000	0.994	0.006
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.006	0.994	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
R26.3 Immobility	0.000	0.994	0.006
G81 Hemiplegia	0.000	0.994	0.006
E55.9 Vitamin D deficiency, unspecified	0.000	0.995	0.005
N64.1 Fat necrosis of breast	0.000	0.995	0.005
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.995	0.005
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.995	0.005
N64.4 Mastodynia	0.000	0.995	0.005
I35.9 Aortic valve disorder, unspecified	0.000	0.995	0.005
N64 Other disorders of breast	0.000	0.995	0.005
G82 Paraplegia and tetraplegia	0.000	0.995	0.005
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.005	0.995	0.000
G81.1 Spastic hemiplegia	0.000	0.995	0.005
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.995	0.005
K86.8 Other specified diseases of pancreas	0.000	0.995	0.005
N64.5 Other signs and symptoms in breast	0.000	0.996	0.004
G81.0 Flaccid hemiplegia	0.000	0.996	0.004
G82.5 Tetraplegia, unspecified	0.000	0.996	0.004
G82.4 Spastic tetraplegia	0.000	0.996	0.004
G82.1 Spastic paraplegia	0.000	0.996	0.004
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.996	0.004
N64.9 Disorder of breast, unspecified	0.000	0.996	0.004
K86 Other diseases of pancreas	0.000	0.996	0.004
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.996	0.004
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.004	0.996	0.000
G82.2 Paraplegia, unspecified	0.000	0.996	0.004
J38.3 Other diseases of vocal cords	0.004	0.996	0.000
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.000	0.996	0.004
J91 Pleural effusion in conditions classified elsewhere	0.004	0.996	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.996	0.004
J38.7 Other diseases of larynx	0.004	0.996	0.000
G82.3 Flaccid tetraplegia	0.000	0.996	0.004
G82.0 Flaccid paraplegia	0.000	0.996	0.004
N64.3 Galactorrhoea not associated with childbirth	0.000	0.996	0.004
N64.2 Atrophy of breast	0.000	0.996	0.004
N64.0 Fissure and fistula of nipple	0.000	0.996	0.004
C34.1 Upper lobe, bronchus or lung	0.000	0.996	0.004
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.996	0.004
I35 Nonrheumatic aortic valve disorders	0.000	0.997	0.003
K86.2 Cyst of pancreas	0.000	0.997	0.003
N81.5 Vaginal enterocele	0.000	0.997	0.003
O15 Eclampsia	0.000	0.997	0.003
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.997	0.003
E55 Vitamin D deficiency	0.000	0.997	0.003
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.997	0.003
S90.0 Contusion of ankle	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
R22.2 Localised swelling, mass and lump, trunk	0.003	0.997	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.997	0.003
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.003	0.997	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.997	0.003
O14.2 HELLP syndrome	0.000	0.997	0.003
J38.0 Paralysis of vocal cords and larynx	0.003	0.997	0.000
R25 Abnormal involuntary movements	0.000	0.997	0.003
O14.0 Moderate preeclampsia	0.000	0.997	0.003
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
I05.0 Mitral stenosis	0.000	0.997	0.003
O15.9 Eclampsia, unspecified as to time period	0.000	0.997	0.002
O15.2 Eclampsia in the puerperium	0.000	0.997	0.002
O15.1 Eclampsia in labour	0.000	0.997	0.002
O15.0 Eclampsia in pregnancy	0.000	0.997	0.002
O14.1 Severe preeclampsia	0.000	0.997	0.003
J38.6 Stenosis of larynx	0.002	0.997	0.000
E55.0 Rickets, active	0.000	0.997	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.003
O81.3 Other and unspecified forceps delivery	0.003	0.997	0.000
L93.0 Discoid lupus erythematosus	0.000	0.997	0.003
H59.0 Vitreous syndrome following cataract surgery	0.000	0.997	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.997	0.000
G80 Infantile cerebral palsy	0.000	0.997	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.997	0.002
K29.0 Acute haemorrhagic gastritis	0.002	0.998	0.000
C56 Malignant neoplasm of ovary	0.000	0.998	0.002
O43.1 Malformation of placenta	0.000	0.998	0.002
Z86.0 Personal history of other neoplasms	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.002	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.002	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.002	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.002	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.002	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.002	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.002	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
K65.8 Other peritonitis	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M15.8 Other polyarthrosis	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
M15.1 Heberden's nodes (with arthropathy)	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
N60-N64 Disorders of breast	0.000	0.998	0.002
F17.1 Harmful use	0.000	0.998	0.002
G80.1 Spastic diplegia	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.000	0.998	0.002
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
M15.3 Secondary multiple arthrosis	0.002	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z31.2 In vitro fertilisation	0.000	0.998	0.002
G80.8 Other infantile cerebral palsy	0.000	0.998	0.002
R23.4 Changes in skin texture	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
C22.9 Liver, unspecified	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
G83 Other paralytic syndromes	0.000	0.998	0.002
M15 Polyarthrosis	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
O12.1 Gestational proteinuria	0.000	0.998	0.002
D29.1 Prostate	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
K25.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
H33 Retinal detachments and breaks	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Y42.4 Oral contraceptives	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.000	0.998	0.002
G43.9 Migraine, unspecified	0.000	0.998	0.002
H33.5 Other retinal detachments	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
D07.5 Prostate	0.000	0.998	0.002
K07.1 Anomalies of jaw-cranial base relationship	0.002	0.998	0.000
M15.0 Primary generalised (osteo)arthrosis	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.002	0.998	0.000
K51.8 Other ulcerative colitis	0.002	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
N64.8 Other specified disorders of breast	0.000	0.998	0.002
O43.8 Other placental disorders	0.000	0.998	0.002
Y42.2 Antithyroid drugs	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.002
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
C71.1 Frontal lobe	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.000	0.998	0.002
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.000	0.998	0.002
R25.3 Fasciculation	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
H33.4 Traction detachment of retina	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
W44.0 Home	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.001
G83.5 Locked-in syndrome	0.000	0.998	0.001
G83.3 Monoplegia, unspecified	0.000	0.998	0.001
G83.0 Diplegia of upper limbs	0.000	0.998	0.001
I05.8 Other mitral valve diseases	0.000	0.998	0.001
R25.1 Tremor, unspecified	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
O43 Placental disorders	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
W50.9 Unspecified place	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.000	0.998	0.002
M15.4 Erosive (osteo)arthrosis	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.998	0.002
O12.0 Gestational oedema	0.000	0.998	0.001
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
G83.1 Monoplegia of lower limb	0.000	0.998	0.001
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
M15.9 Polyarthrosis, unspecified	0.001	0.998	0.000
Y46.4 Iminostilbenes	0.000	0.998	0.001
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
D35.0 Adrenal gland	0.000	0.998	0.002
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
T86.4 Liver transplant failure and rejection	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.001
Y48.5 Therapeutic gases	0.000	0.998	0.001
Y48.1 Parenteral anaesthetics	0.000	0.998	0.001
Y48.0 Inhaled anaesthetics	0.000	0.998	0.001
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.998	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.998	0.000
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.998	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.998	0.000
Y46.8 Antispasticity drugs	0.000	0.998	0.001
Y46.7 Anti-Parkinsonism drugs	0.000	0.998	0.001
Y46.5 Valproic acid	0.000	0.998	0.001
Y46.3 Deoxybarbiturates	0.000	0.998	0.001
Y46.1 Oxazolidinediones	0.000	0.998	0.001
Y46.0 Succinimides	0.000	0.998	0.001
Y48.3 Local anaesthetics	0.000	0.998	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.001	0.998	0.000
O81.0 Low forceps delivery	0.001	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.998	0.000
Y52.7 Peripheral vasodilators	0.000	0.998	0.001
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.001
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
C71.4 Occipital lobe	0.001	0.999	0.000
C71.0 Cerebrum, except lobes and ventricles	0.001	0.999	0.000
G83.2 Monoplegia of upper limb	0.000	0.999	0.001
I74.8 Embolism and thrombosis of other arteries	0.000	0.999	0.001
J98.9 Respiratory disorder, unspecified	0.000	0.999	0.001
L98.8 Other specified disorders of skin and subcutaneous tissue	0.001	0.999	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.999	0.001
O43.2 Morbidly adherent placenta	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.999	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.999	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.999	0.001
Y49.9 Psychotropic drug, unspecified	0.000	0.999	0.001
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
Y49.7 Psychostimulants with abuse potential	0.000	0.999	0.001
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.999	0.001
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.999	0.001
M53 Other dorsopathies, not elsewhere classified	0.001	0.999	0.000
Y95 Nosocomial condition	0.000	0.999	0.001
M53.96 Dorsopathy, unspecified (Lumbar region)	0.001	0.999	0.000
C18.3 Hepatic flexure	0.000	0.999	0.001
H53.8 Other visual disturbances	0.000	0.999	0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.999	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.999	0.001
M53.9 Dorsopathy, unspecified	0.001	0.999	0.000
O43.9 Placental disorder, unspecified	0.000	0.999	0.001
O43.0 Placental transfusion syndromes	0.000	0.999	0.001
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.999	0.001
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.000	0.999	0.001
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.999	0.001
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.999	0.001
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.999	0.001
Y47.4 Bromine compounds	0.000	0.999	0.001
Y47.3 Paraldehyde	0.000	0.999	0.001
Y47.2 Chloral derivatives	0.000	0.999	0.001
Y47.0 Barbiturates, not elsewhere classified	0.000	0.999	0.001
Z31.8 Other procreative management	0.000	0.999	0.001
T86 Failure and rejection of transplanted organs and tissues	0.000	0.999	0.001
C71.8 Overlapping lesion of brain	0.001	0.999	0.000
C71.6 Cerebellum	0.001	0.999	0.000
C71.5 Cerebral ventricle	0.001	0.999	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.999	0.001
N80.9 Endometriosis, unspecified	0.001	0.999	0.000
O32.4 Maternal care for high head at term	0.000	0.999	0.001
R22.0 Localised swelling, mass and lump, head	0.001	0.999	0.000
Y52.1 Calcium-channel blockers	0.000	0.999	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.999	0.001
X78.0 Home	0.000	0.999	0.001
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
H18.4 Corneal degeneration	0.000	0.999	0.001
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
Y58 Bacterial vaccines	0.000	0.999	0.001
Z31 Procreative management	0.000	0.999	0.001
E50-E64 Other nutritional deficiencies	0.000	0.999	0.001
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.999	0.001
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
K07.9 Dentofacial anomaly, unspecified	0.001	0.999	0.000
K07.4 Malocclusion, unspecified	0.001	0.999	0.000
M53.2 Spinal instabilities	0.001	0.999	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.000	0.999	0.001
W50.2 School, other institution and public administrative area	0.001	0.999	0.000
C71.3 Parietal lobe	0.001	0.999	0.000
F17.2 Dependence syndrome	0.000	0.999	0.001
K07.8 Other dentofacial anomalies	0.001	0.999	0.000
K07.5 Dentofacial functional abnormalities	0.001	0.999	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.999	0.001
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.999	0.001
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.999	0.001
C22.7 Other specified carcinomas of liver	0.000	0.999	0.001
C22.4 Other sarcomas of liver	0.000	0.999	0.001
C22.3 Angiosarcoma of liver	0.000	0.999	0.001
C22.2 Hepatoblastoma	0.000	0.999	0.001
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.999	0.001
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
E51 Thiamine deficiency	0.000	0.999	0.001
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.999	0.001
Y59 Other and unspecified vaccines and biological substances	0.000	0.999	0.001
D06.9 Cervix, unspecified	0.001	0.999	0.000
M53.1 Cervicobrachial syndrome	0.001	0.999	0.000
M53.0 Cervicocranial syndrome	0.001	0.999	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.001	0.999	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
M53.22 Spinal instabilities (Cervical region)	0.001	0.999	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.001	0.999	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.001	0.999	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.001	0.999	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.001	0.999	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
O32.0 Maternal care for unstable lie	0.000	0.999	0.001
S30.0 Contusion of lower back and pelvis	0.000	0.999	0.001
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.999	0.001
T86.3 Heart-lung transplant failure and rejection	0.000	0.999	0.001
T86.2 Heart transplant failure and rejection	0.000	0.999	0.001
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.999	0.001
E51.2 Wernicke's encephalopathy	0.000	0.999	0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
K07.3 Anomalies of tooth position	0.001	0.999	0.000
K07.0 Major anomalies of jaw size	0.001	0.999	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.000	0.999	0.001
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations