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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6899950
log Bayes Factor = 29.2397
Chromosome 6   position 27,433,995  (GRCh37) Explore rs6899950 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.672 0.328
E83 Disorders of mineral metabolism
0.000 0.691 0.309
E10.9 Without complications
0.000 0.693 0.307
E10.5 With peripheral circulatory complications
0.000 0.699 0.301
E10.1 With ketoacidosis
0.000 0.703 0.297
E10.3 With ophthalmic complications
0.000 0.711 0.289
E10-E14 Diabetes mellitus
0.000 0.711 0.289
E10.8 With unspecified complications
0.000 0.713 0.287
E70-E90 Metabolic disorders
0.000 0.729 0.271
E88 Other metabolic disorders
0.000 0.731 0.269
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.732 0.268
E10.4 With neurological complications
0.000 0.736 0.264
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.738 0.262
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.747 0.253
E10.0 With coma
0.000 0.750 0.250
E13 Other specified diabetes mellitus
0.000 0.753 0.246
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.757 0.243
E16 Other disorders of pancreatic internal secretion
0.000 0.757 0.243
E10.6 With other specified complications
0.000 0.759 0.241
E16.2 Hypoglycaemia, unspecified
0.000 0.763 0.237
E10.7 With multiple complications
0.000 0.765 0.235
E10.2 With renal complications
0.000 0.767 0.233
E80.4 Gilbert's syndrome
0.000 0.777 0.223
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.778 0.222
E83.8 Other disorders of mineral metabolism
0.000 0.778 0.222
E83.2 Disorders of zinc metabolism
0.000 0.778 0.222
E83.0 Disorders of copper metabolism
0.000 0.778 0.222
E88.8 Other specified metabolic disorders
0.000 0.781 0.219
E13.9 Without complications
0.000 0.784 0.216
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.790 0.210
E12 Malnutrition-related diabetes mellitus
0.000 0.792 0.207
E40-E46 Malnutrition
0.000 0.792 0.207
E88.3 Tumour lysis syndrome
0.000 0.794 0.206
E88.2 Lipomatosis, not elsewhere classified
0.000 0.797 0.202
E84 Cystic fibrosis
0.000 0.805 0.195
E77 Disorders of glycoprotein metabolism
0.000 0.805 0.195
E76 Disorders of glycosaminoglycan metabolism
0.000 0.805 0.195
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.805 0.195
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.805 0.195
E27.1 Primary adrenocortical insufficiency
0.000 0.807 0.193
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.809 0.191
E20-E35 Disorders of other endocrine glands
0.000 0.809 0.191
E70 Disorders of aromatic amino-acid metabolism
0.000 0.809 0.191
E72 Other disorders of amino-acid metabolism
0.000 0.811 0.189
E88.9 Metabolic disorder, unspecified
0.000 0.811 0.189
E27 Other disorders of adrenal gland
0.000 0.813 0.187
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.816 0.184
E15 Nondiabetic hypoglycaemic coma
0.000 0.818 0.182
K90 Intestinal malabsorption
0.000 0.819 0.180
E14 Unspecified diabetes mellitus
0.000 0.819 0.180
E80.6 Other disorders of bilirubin metabolism
0.000 0.821 0.179
E13.3 With ophthalmic complications
0.000 0.823 0.177
E13.8 With unspecified complications
0.000 0.823 0.177
E13.7 With multiple complications
0.000 0.823 0.177
E13.6 With other specified complications
0.000 0.823 0.177
E13.5 With peripheral circulatory complications
0.000 0.823 0.177
E13.4 With neurological complications
0.000 0.823 0.177
E13.2 With renal complications
0.000 0.823 0.177
E13.1 With ketoacidosis
0.000 0.823 0.177
E13.0 With coma
0.000 0.823 0.177
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.826 0.174
E80.5 Crigler-Najjar syndrome
0.000 0.826 0.174
E80.3 Defects of catalase and peroxydase
0.000 0.826 0.174
E80.1 Porphyria cutanea tarda
0.000 0.826 0.174
E80.0 Hereditary erythropoietic porphyria
0.000 0.826 0.174
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.826 0.174
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.826 0.174
E16.4 Abnormal secretion of gastrin
0.000 0.826 0.174
E16.3 Increased secretion of glucagon
0.000 0.826 0.174
E14.3 With ophthalmic complications
0.000 0.831 0.169
E79 Disorders of purine and pyrimidine metabolism
0.000 0.832 0.168
E80.2 Other porphyria
0.000 0.833 0.167
E20 Hypoparathyroidism
0.000 0.836 0.164
E46 Unspecified protein-energy malnutrition
0.000 0.836 0.164
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.836 0.164
E65-E68 Obesity and other hyperalimentation
0.000 0.837 0.163
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.838 0.162
E29 Testicular dysfunction
0.000 0.842 0.158
E73 Lactose intolerance
0.000 0.843 0.156
E74 Other disorders of carbohydrate metabolism
0.000 0.845 0.155
E12.9 Without complications
0.000 0.851 0.149
E12.8 With unspecified complications
0.000 0.851 0.149
E12.7 With multiple complications
0.000 0.851 0.149
E12.6 With other specified complications
0.000 0.851 0.149
E12.5 With peripheral circulatory complications
0.000 0.851 0.149
E12.4 With neurological complications
0.000 0.851 0.149
E12.3 With ophthalmic complications
0.000 0.851 0.149
E12.2 With renal complications
0.000 0.851 0.149
E12.1 With ketoacidosis
0.000 0.851 0.149
E12.0 With coma
0.000 0.851 0.149
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.851 0.149
E45 Retarded development following protein-energy malnutrition
0.000 0.851 0.149
E43 Unspecified severe protein-energy malnutrition
0.000 0.851 0.149
E42 Marasmic kwashiorkor
0.000 0.851 0.149
E41 Nutritional marasmus
0.000 0.851 0.149
E40 Kwashiorkor
0.000 0.851 0.149
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.852 0.148
E20.9 Hypoparathyroidism, unspecified
0.000 0.855 0.145
E16.1 Other hypoglycaemia
0.000 0.857 0.143
E83.3 Disorders of phosphorus metabolism
0.000 0.858 0.142
E24 Cushing's syndrome
0.000 0.859 0.141
E71.3 Disorders of fatty-acid metabolism
0.000 0.860 0.140
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.860 0.140
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.860 0.140
E71.0 Maple-syrup-urine disease
0.000 0.860 0.140
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.860 0.140
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.860 0.140
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.860 0.140
E76.2 Other mucopolysaccharidoses
0.000 0.860 0.140
E76.1 Mucopolysaccharidosis, type II
0.000 0.860 0.140
E76.0 Mucopolysaccharidosis, type I
0.000 0.860 0.140
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.860 0.140
E77.8 Other disorders of glycoprotein metabolism
0.000 0.860 0.140
E77.1 Defects in glycoprotein degradation
0.000 0.860 0.140
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.860 0.140
E84.9 Cystic fibrosis, unspecified
0.000 0.860 0.140
E84.8 Cystic fibrosis with other manifestations
0.000 0.860 0.140
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.860 0.140
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.860 0.140
E14.5 With peripheral circulatory complications
0.000 0.860 0.139
E14.2 Withrenal complications
0.000 0.862 0.138
E26 Hyperaldosteronism
0.000 0.862 0.138
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.863 0.137
E32 Diseases of thymus
0.000 0.863 0.137
E31 Polyglandular dysfunction
0.000 0.863 0.137
E30 Disorders of puberty, not elsewhere classified
0.000 0.863 0.137
E25 Adrenogenital disorders
0.000 0.863 0.137
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.863 0.137
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.863 0.137
E70.2 Disorders of tyrosine metabolism
0.000 0.863 0.137
E70.1 Other hyperphenylalaninaemias
0.000 0.863 0.137
E70.0 Classical phenylketonuria
0.000 0.863 0.137
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.863 0.137
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.864 0.136
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.864 0.136
E72.5 Disorders of glycine metabolism
0.000 0.864 0.136
E72.4 Disorders of ornithine metabolism
0.000 0.864 0.136
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.864 0.136
E72.2 Disorders of urea cycle metabolism
0.000 0.864 0.136
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.864 0.136
E65 Localised adiposity
0.000 0.864 0.136
E11 Non-insulin-dependent diabetes mellitus
0.000 0.865 0.135
E29.1 Testicular hypofunction
0.000 0.865 0.135
E27.5 Adrenomedullary hyperfunction
0.000 0.866 0.134
E27.0 Other adrenocortical overactivity
0.000 0.866 0.134
E70.3 Albinism
0.000 0.867 0.133
E75.6 Lipid storage disorder, unspecified
0.000 0.868 0.132
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.868 0.132
E75.3 Sphingolipidosis, unspecified
0.000 0.868 0.132
E75.2 Other sphingolipidosis
0.000 0.868 0.132
E75.1 Other gangliosidosis
0.000 0.868 0.132
E75.0 GM2 gangliosidosis
0.000 0.868 0.132
E78.4 Other hyperlipidaemia
0.000 0.869 0.131
E72.0 Disorders of amino-acid transport
0.000 0.869 0.130
K90.3 Pancreatic steatorrhoea
0.000 0.870 0.130
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.870 0.130
K90.1 Tropical sprue
0.000 0.870 0.130
E14.7 With multiple complications
0.000 0.870 0.130
E14.0 With coma
0.000 0.870 0.130
E11.2 With renal complications
0.000 0.872 0.128
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.875 0.125
E14.1 With ketoacidosis
0.000 0.876 0.124
E24.2 Drug-induced Cushing's syndrome
0.000 0.877 0.123
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.877 0.122
E14.6 With other specified complications
0.000 0.878 0.122
E78.1 Pure hyperglyceridaemia
0.000 0.878 0.122
E75.5 Other lipid storage disorders
0.000 0.879 0.121
E27.2 Addisonian crisis
0.000 0.879 0.121
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.879 0.120
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.879 0.120
E79.1 Lesch-Nyhan syndrome
0.000 0.879 0.120
E78.6 Lipoprotein deficiency
0.000 0.881 0.119
E20.8 Other hypoparathyroidism
0.000 0.882 0.118
E20.1 Pseudohypoparathyroidism
0.000 0.882 0.118
E20.0 Idiopathic hypoparathyroidism
0.000 0.882 0.118
E78.3 Hyperchylomicronaemia
0.000 0.882 0.118
E34 Other endocrine disorders
0.000 0.883 0.117
E67 Other hyperalimentation
0.000 0.883 0.117
E68 Sequelae of hyperalimentation
0.000 0.883 0.117
E85 Amyloidosis
0.000 0.886 0.114
E29.9 Testicular dysfunction, unspecified
0.000 0.886 0.114
E29.8 Other testicular dysfunction
0.000 0.886 0.114
E29.0 Testicular hyperfunction
0.000 0.886 0.114
K90.8 Other intestinal malabsorption
0.000 0.886 0.113
E73.8 Other lactose intolerance
0.000 0.887 0.112
E73.1 Secondary lactase deficiency
0.000 0.887 0.112
E73.0 Congenital lactase deficiency
0.000 0.887 0.112
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.889 0.111
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.889 0.111
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.889 0.111
E74.2 Disorders of galactose metabolism
0.000 0.889 0.111
E74.1 Disorders of fructose metabolism
0.000 0.889 0.111
E44.1 Mild protein-energy malnutrition
0.000 0.893 0.107
E44.0 Moderate protein-energy malnutrition
0.000 0.893 0.107
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.894 0.106
E26.0 Primary hyperaldosteronism
0.000 0.897 0.103
E11.6 With other specified complications
0.000 0.897 0.103
E14.4 With neurological complications
0.000 0.898 0.102
E11.1 With ketoacidosis
0.000 0.898 0.102
E24.8 Other Cushing's syndrome
0.000 0.899 0.101
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.899 0.101
E24.3 Ectopic ACTH syndrome
0.000 0.899 0.101
E24.1 Nelson's syndrome
0.000 0.899 0.101
E23 Hypofunction and other disorders of pituitary gland
0.000 0.900 0.100
E89.4 Postprocedural ovarian failure
0.000 0.900 0.100
E26.8 Other hyperaldosteronism
0.000 0.901 0.099
E26.1 Secondary hyperaldosteronism
0.000 0.901 0.099
E11.0 With coma
0.000 0.901 0.099
E11.8 With unspecified complications
0.000 0.901 0.099
E25.9 Adrenogenital disorder, unspecified
0.000 0.901 0.099
E25.8 Other adrenogenital disorders
0.000 0.901 0.099
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.901 0.099
E30.9 Disorder of puberty, unspecified
0.000 0.901 0.099
E30.8 Other disorders of puberty
0.000 0.901 0.099
E30.1 Precocious puberty
0.000 0.901 0.099
E30.0 Delayed puberty
0.000 0.901 0.099
E31.9 Polyglandular dysfunction, unspecified
0.000 0.901 0.099
E31.8 Other polyglandular dysfunction
0.000 0.901 0.099
E31.1 Polyglandular hyperfunction
0.000 0.901 0.099
E31.0 Autoimmune polyglandular failure
0.000 0.901 0.099
E32.9 Disease of thymus, unspecified
0.000 0.901 0.099
E32.8 Other diseases of thymus
0.000 0.901 0.099
E32.1 Abscess of thymus
0.000 0.901 0.099
E32.0 Persistent hyperplasia of thymus
0.000 0.901 0.099
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.901 0.099
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.901 0.099
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.901 0.099
E27.8 Other specified disorders of adrenal gland
0.000 0.902 0.098
E11.7 With multiple complications
0.000 0.903 0.097
E74.0 Glycogen storage disease
0.000 0.903 0.097
E24.0 Pituitary-dependent Cushing's disease
0.000 0.903 0.097
E78.2 Mixed hyperlipidaemia
0.000 0.903 0.097
E26.9 Hyperaldosteronism, unspecified
0.000 0.905 0.095
E14.8 With unspecified complications
0.000 0.905 0.095
E83.4 Disorders of magnesium metabolism
0.000 0.905 0.094
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.906 0.093
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.908 0.092
E34.9 Endocrine disorder, unspecified
0.000 0.909 0.090
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.910 0.090
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.910 0.090
E89.5 Postprocedural testicular hypofunction
0.000 0.910 0.090
E34.5 Androgen resistance syndrome
0.000 0.916 0.084
E34.4 Constitutional tall stature
0.000 0.916 0.084
E34.3 Short stature, not elsewhere classified
0.000 0.916 0.084
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.916 0.084
E34.1 Other hypersecretion of intestinal hormones
0.000 0.916 0.084
E67.8 Other specified hyperalimentation
0.000 0.916 0.084
E67.3 Hypervitaminosis D
0.000 0.916 0.084
E67.2 Megavitamin-B6 syndrome
0.000 0.916 0.084
E67.1 Hypercarotenaemia
0.000 0.916 0.084
E67.0 Hypervitaminosis A
0.000 0.916 0.084
E11.5 With peripheral circulatory complications
0.000 0.918 0.082
E85.8 Other amyloidosis
0.000 0.918 0.082
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.918 0.082
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.918 0.082
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.918 0.082
M25.57 Pain in joint (Ankle and foot)
0.000 0.918 0.082
E89.1 Postprocedural hypoinsulinaemia
0.000 0.919 0.081
E11.4 With neurological complications
0.000 0.919 0.081
E23.2 Diabetes insipidus
0.000 0.922 0.078
E23.7 Disorder of pituitary gland, unspecified
0.000 0.923 0.077
E78.8 Other disorders of lipoprotein metabolism
0.000 0.925 0.075
E34.0 Carcinoid syndrome
0.000 0.925 0.074
E73.9 Lactose intolerance, unspecified
0.000 0.926 0.074
E89.0 Postprocedural hypothyroidism
0.000 0.928 0.072
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.928 0.072
E23.1 Drug-induced hypopituitarism
0.000 0.928 0.072
E85.9 Amyloidosis, unspecified
0.000 0.928 0.071
E28 Ovarian dysfunction
0.000 0.929 0.070
E24.9 Cushing's syndrome, unspecified
0.000 0.930 0.070
E85.3 Secondary systemic amyloidosis
0.000 0.934 0.066
E34.8 Other specified endocrine disorders
0.000 0.935 0.065
E83.5 Disorders of calcium metabolism
0.000 0.935 0.065
E22 Hyperfunction of pituitary gland
0.000 0.937 0.063
E23.6 Other disorders of pituitary gland
0.000 0.938 0.062
E27.9 Disorder of adrenal gland, unspecified
0.001 0.938 0.061
K90.9 Intestinal malabsorption, unspecified
0.000 0.941 0.059
E85.4 Organ-limited amyloidosis
0.000 0.942 0.058
E50-E64 Other nutritional deficiencies
0.000 0.943 0.057
E89.2 Postprocedural hypoparathyroidism
0.000 0.945 0.054
E89.3 Postprocedural hypopituitarism
0.000 0.948 0.052
E28.9 Ovarian dysfunction, unspecified
0.000 0.949 0.051
E28.8 Other ovarian dysfunction
0.000 0.949 0.051
E28.1 Androgen excess
0.000 0.949 0.051
E28.0 Oestrogen excess
0.000 0.949 0.051
E22.8 Other hyperfunction of pituitary gland
0.000 0.954 0.045
E22.1 Hyperprolactinaemia
0.000 0.955 0.045
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.959 0.041
E63 Other nutritional deficiencies
0.000 0.959 0.041
E50 Vitamin A deficiency
0.000 0.959 0.041
E60 Dietary zinc deficiency
0.000 0.959 0.041
E59 Dietary selenium deficiency
0.000 0.959 0.041
E52 Niacin deficiency [pellagra]
0.000 0.959 0.041
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.959 0.041
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.960 0.040
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.961 0.039
E51 Thiamine deficiency
0.000 0.961 0.038
E56 Other vitamin deficiencies
0.000 0.961 0.038
E58 Dietary calcium deficiency
0.000 0.962 0.038
M25.5 Pain in joint
0.000 0.963 0.037
E54 Ascorbic acid deficiency
0.000 0.964 0.036
E66 Obesity
0.000 0.964 0.036
E53 Deficiency of other B group vitamins
0.000 0.966 0.034
E55 Vitamin D deficiency
0.000 0.967 0.033
E14.9 Without complications
0.000 0.969 0.031
E00-E07 Disorders of thyroid gland
0.000 0.969 0.031
E21.2 Other hyperparathyroidism
0.000 0.969 0.031
E11.3 With ophthalmic complications
0.000 0.969 0.031
E28.2 Polycystic ovarian syndrome
0.000 0.970 0.030
E50.9 Vitamin A deficiency, unspecified
0.000 0.970 0.029
E50.8 Other manifestations of vitamin A deficiency
0.000 0.970 0.029
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.970 0.029
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.970 0.029
E50.5 Vitamin A deficiency with night blindness
0.000 0.970 0.029
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.970 0.029
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.970 0.029
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.970 0.029
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.970 0.029
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.970 0.029
E63.9 Nutritional deficiency, unspecified
0.000 0.970 0.029
E63.8 Other specified nutritional deficiencies
0.000 0.970 0.029
E63.1 Imbalance of constituents of food intake
0.000 0.970 0.029
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.970 0.029
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.970 0.029
E64.8 Sequelae of other nutritional deficiencies
0.000 0.970 0.029
E64.3 Sequelae of rickets
0.000 0.970 0.029
E64.2 Sequelae of vitamin C deficiency
0.000 0.970 0.029
E64.1 Sequelae of vitamin A deficiency
0.000 0.970 0.029
E64.0 Sequelae of protein-energy malnutrition
0.000 0.970 0.029
M25.58 Pain in joint (Other)
0.000 0.970 0.030
M25.51 Pain in joint (Shoulder region)
0.000 0.971 0.029
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.971 0.029
M25.52 Pain in joint (Upper arm)
0.000 0.971 0.029
E28.3 Primary ovarian failure
0.001 0.971 0.028
E21.4 Other specified disorders of parathyroid gland
0.000 0.972 0.028
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.972 0.028
E22.0 Acromegaly and pituitary gigantism
0.000 0.972 0.028
E51.9 Thiamine deficiency, unspecified
0.000 0.972 0.028
E51.8 Other manifestations of thiamine deficiency
0.000 0.972 0.028
E51.1 Beriberi
0.000 0.972 0.028
E56.9 Vitamin deficiency, unspecified
0.000 0.972 0.027
E56.8 Deficiency of other vitamins
0.000 0.972 0.027
E56.0 Deficiency of vitamin E
0.000 0.972 0.027
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.973 0.027
E53.9 Vitamin B deficiency, unspecified
0.000 0.973 0.026
E66.1 Drug-induced obesity
0.000 0.974 0.026
M25.53 Pain in joint (Forearm)
0.000 0.974 0.026
E51.2 Wernicke's encephalopathy
0.000 0.975 0.025
E56.1 Deficiency of vitamin K
0.000 0.975 0.025
E53.1 Pyridoxine deficiency
0.000 0.975 0.024
E53.0 Riboflavin deficiency
0.000 0.975 0.024
E61 Deficiency of other nutrient elements
0.001 0.976 0.024
E55.0 Rickets, active
0.000 0.976 0.024
E23.0 Hypopituitarism
0.000 0.976 0.024
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.977 0.022
E00 Congenital iodine-deficiency syndrome
0.000 0.977 0.022
E66.0 Obesity due to excess calories
0.000 0.978 0.022
E21.0 Primary hyperparathyroidism
0.000 0.978 0.022
E06 Thyroiditis
0.000 0.981 0.019
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.982 0.018
E07 Other disorders of thyroid
0.000 0.982 0.018
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.982 0.018
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.982 0.018
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.982 0.018
E61.9 Deficiency of nutrient element, unspecified
0.001 0.982 0.017
E61.8 Deficiency of other specified nutrient elements
0.001 0.982 0.017
E61.7 Deficiency of multiple nutrient elements
0.001 0.982 0.017
E61.6 Vanadium deficiency
0.001 0.982 0.017
E61.5 Molybdenum deficiency
0.001 0.982 0.017
E61.4 Chromium deficiency
0.001 0.982 0.017
E61.3 Manganese deficiency
0.001 0.982 0.017
E61.0 Copper deficiency
0.001 0.982 0.017
M25.59 Pain in joint (Site unspecified)
0.000 0.983 0.017
G30.9 Alzheimer's disease, unspecified
0.000 0.984 0.016
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.984 0.016
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.984 0.016
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.984 0.016
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.984 0.016
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.984 0.016
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.984 0.016
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.984 0.016
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.984 0.016
E61.2 Magnesium deficiency
0.001 0.984 0.016
E55.9 Vitamin D deficiency, unspecified
0.000 0.984 0.016
M25.54 Pain in joint (Hand)
0.000 0.984 0.016
K90-K93 Other diseases of the digestive system
0.000 0.984 0.016
E03 Other hypothyroidism
0.000 0.985 0.015
E06.5 Other chronic thyroiditis
0.000 0.985 0.015
E21.3 Hyperparathyroidism, unspecified
0.000 0.985 0.015
G30 Alzheimer's disease
0.000 0.985 0.015
E05.8 Other thyrotoxicosis
0.000 0.985 0.015
E86 Volume depletion
0.000 0.986 0.014
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.986 0.014
E06.4 Drug-induced thyroiditis
0.000 0.986 0.014
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.986 0.014
E06.1 Subacute thyroiditis
0.000 0.986 0.014
E06.0 Acute thyroiditis
0.000 0.986 0.014
E53.8 Deficiency of other specified B group vitamins
0.000 0.986 0.014
E87.7 Fluid overload
0.000 0.987 0.013
E05.5 Thyroid crisis or storm
0.000 0.987 0.013
E05.4 Thyrotoxicosis factitia
0.000 0.987 0.013
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.987 0.013
E07.1 Dyshormogenetic goitre
0.000 0.987 0.013
E07.0 Hypersecretion of calcitonin
0.000 0.987 0.013
E87.4 Mixed disorder of acid-base balance
0.000 0.987 0.013
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.987 0.013
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.987 0.013
E87.5 Hyperkalaemia
0.000 0.987 0.013
E06.3 Autoimmune thyroiditis
0.000 0.987 0.013
E87.3 Alkalosis
0.000 0.987 0.013
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.987 0.013
G31.8 Other specified degenerative diseases of nervous system
0.000 0.988 0.012
E07.8 Other specified disorders of thyroid
0.000 0.988 0.012
G30.0 Alzheimer's disease with early onset
0.000 0.988 0.012
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.988 0.012
G30-G32 Other degenerative diseases of the nervous system
0.000 0.988 0.012
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.988 0.012
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.988 0.012
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.012 0.988 0.000
M25.50 Pain in joint (Multiple sites)
0.000 0.988 0.011
E03.8 Other specified hypothyroidism
0.000 0.988 0.011
E87.2 Acidosis
0.000 0.988 0.011
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.989 0.011
E03.5 Myxoedema coma
0.000 0.989 0.011
E03.4 Atrophy of thyroid (acquired)
0.000 0.989 0.011
E03.3 Postinfectious hypothyroidism
0.000 0.989 0.011
E03.1 Congenital hypothyroidism without goitre
0.000 0.989 0.011
G31.0 Circumscribed brain atrophy
0.000 0.989 0.011
G30.1 Alzheimer's disease with late onset
0.000 0.989 0.011
E06.9 Thyroiditis, unspecified
0.000 0.989 0.011
G30.8 Other Alzheimer's disease
0.000 0.989 0.011
E07.9 Disorder of thyroid, unspecified
0.000 0.989 0.011
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.989 0.011
E66.9 Obesity, unspecified
0.000 0.990 0.010
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.991 0.009
E04 Other non-toxic goitre
0.000 0.991 0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.992 0.008
K93.1 Megacolon in Chagas' disease
0.000 0.992 0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.992 0.008
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.992 0.008
K51.2 Ulcerative (chronic) proctitis
0.008 0.992 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.992 0.008
K56.4 Other impaction of intestine
0.007 0.993 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.993 0.007
E04.8 Other specified non-toxic goitre
0.000 0.993 0.007
G31.2 Degeneration of nervous system due to alcohol
0.000 0.993 0.007
G54.9 Nerve root and plexus disorder, unspecified
0.007 0.993 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.994 0.006
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.994 0.006
E05.9 Thyrotoxicosis, unspecified
0.000 0.994 0.006
F06.7 Mild cognitive disorder
0.006 0.994 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.994 0.005
E61.1 Iron deficiency
0.001 0.995 0.004
M25.56 Pain in joint (Lower leg)
0.000 0.995 0.005
G44.2 Tension-type headache
0.005 0.995 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.995 0.005
E04.9 Non-toxic goitre, unspecified
0.000 0.995 0.005
Z34.9 Supervision of normal pregnancy, unspecified
0.005 0.995 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.995 0.005
M41.9 Scoliosis, unspecified
0.005 0.995 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.005 0.995 0.000
N04.9 Unspecified
0.000 0.995 0.005
K91.5 Postcholecystectomy syndrome
0.000 0.996 0.004
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
K91.3 Postoperative intestinal obstruction
0.000 0.996 0.004
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.004 0.996 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.996 0.004
M94.86 Other specified disorders of cartilage (Lower leg)
0.004 0.996 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.996 0.004
H20.9 Iridocyclitis, unspecified
0.000 0.996 0.004
M13.90 Arthritis, unspecified (Multiple sites)
0.000 0.996 0.004
E11.9 Without complications
0.000 0.996 0.004
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.004 0.996 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.003 0.996 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.003 0.996 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.003 0.996 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.003 0.996 0.000
K91.1 Postgastric surgery syndromes
0.000 0.996 0.003
E87.6 Hypokalaemia
0.000 0.996 0.004
R49.0 Dysphonia
0.000 0.997 0.003
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.003 0.997 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.003 0.997 0.000
M43.62 Torticollis-Cervical
0.003 0.997 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.003 0.997 0.000
J06.9 Acute upper respiratory infection, unspecified
0.000 0.997 0.003
J38.3 Other diseases of vocal cords
0.000 0.997 0.003
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.003 0.997 0.000
T78.3 Angioneurotic oedema
0.000 0.997 0.003
M94.8 Other specified disorders of cartilage
0.003 0.997 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.997 0.003
Z94.8 Other transplanted organ and tissue status
0.000 0.997 0.003
F06.6 Organic emotionally labile [asthenic] disorder
0.003 0.997 0.000
F06.5 Organic dissociative disorder
0.003 0.997 0.000
F06.4 Organic anxiety disorder
0.003 0.997 0.000
F06.3 Organic mood [affective] disorders
0.003 0.997 0.000
F06.1 Organic catatonic disorder
0.003 0.997 0.000
F06.0 Organic hallucinosis
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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