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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6904596
log Bayes Factor = 166.569
Chromosome 6   position 27,491,299  (GRCh37) Explore rs6904596 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
K40 Inguinal hernia
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.681 0.004 0.314
N40-N51 Diseases of male genital organs
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.994 0.006 0.000
K40-K46 Hernia
0.001 0.006 0.993
M17 Gonarthrosis [arthrosis of knee]
0.994 0.006 0.000
M15-M19 Arthrosis
0.993 0.007 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.007 0.993
K44 Diaphragmatic hernia
0.000 0.007 0.993
K90-K93 Other diseases of the digestive system
0.681 0.007 0.312
M17.9 Gonarthrosis, unspecified
0.993 0.007 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.993 0.007 0.000
D80-D89 Certain disorders involving the immune mechanism
0.990 0.010 0.000
M20.1 Hallux valgus (acquired)
0.000 0.010 0.990
H25-H28 Disorders of lens
0.990 0.010 0.000
N42 Other disorders of prostate
0.000 0.011 0.989
M20 Acquired deformities of fingers and toes
0.000 0.011 0.989
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.013 0.987
H26 Other cataract
0.986 0.014 0.000
H43-H45 Disorders of vitreous body and globe
0.985 0.015 0.000
H26.9 Cataract, unspecified
0.985 0.015 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.017 0.983
N39 Other disorders of urinary system
0.000 0.020 0.980
N30-N39 Other diseases of urinary system
0.000 0.021 0.979
Chapter XII Diseases of the skin and subcutaneous tissue
0.979 0.021 0.000
H36 Retinal disorders in diseases classified elsewhere
0.979 0.021 0.000
H43 Disorders of vitreous body
0.976 0.024 0.000
E20-E35 Disorders of other endocrine glands
0.975 0.025 0.000
M05-M14 Inflammatory polyarthropathies
0.972 0.028 0.000
E70-E90 Metabolic disorders
0.971 0.029 0.000
E27 Other disorders of adrenal gland
0.971 0.029 0.000
H43.1 Vitreous haemorrhage
0.970 0.030 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.030 0.970
D86 Sarcoidosis
0.969 0.031 0.000
E27.1 Primary adrenocortical insufficiency
0.969 0.031 0.000
N39.8 Other specified disorders of urinary system
0.000 0.034 0.966
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.966 0.034 0.000
H36.0 Diabetic retinopathy
0.965 0.035 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.037 0.963
N32 Other disorders of bladder
0.000 0.041 0.959
H46-H48 Disorders of optic nerve and visual pathways
0.958 0.042 0.000
M23 Internal derangement of knee
0.957 0.043 0.000
N32.0 Bladder-neck obstruction
0.000 0.043 0.957
D86.9 Sarcoidosis, unspecified
0.948 0.052 0.000
K90 Intestinal malabsorption
0.908 0.052 0.040
N42.8 Other specified disorders of prostate
0.000 0.053 0.947
E14 Unspecified diabetes mellitus
0.947 0.053 0.000
H34 Retinal vascular occlusions
0.947 0.053 0.000
L50-L54 Urticaria and erythema
0.941 0.059 0.000
N41 Inflammatory diseases of prostate
0.000 0.063 0.937
E10.1 With ketoacidosis
0.935 0.065 0.000
E78.5 Hyperlipidaemia, unspecified
0.933 0.067 0.000
Chapter XIV Diseases of the genitourinary system
0.001 0.071 0.928
L20-L30 Dermatitis and eczema
0.928 0.072 0.000
M17.1 Other primary gonarthrosis
0.926 0.074 0.000
M22 Disorders of patella
0.922 0.078 0.000
L40-L45 Papulosquamous disorders
0.921 0.079 0.000
M35.3 Polymyalgia rheumatica
0.919 0.081 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.919 0.081 0.000
M31 Other necrotising vasculopathies
0.918 0.082 0.000
E10.2 With renal complications
0.911 0.089 0.000
M60-M63 Disorders of muscles
0.910 0.090 0.000
M23.3 Other meniscus derangements
0.907 0.093 0.000
E14.3 With ophthalmic complications
0.906 0.094 0.000
M11 Other crystal arthropathies
0.906 0.094 0.000
L43 Lichen planus
0.904 0.096 0.000
M34 Systemic sclerosis
0.904 0.096 0.000
M70-M79 Other soft tissue disorders
0.899 0.101 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.102 0.898
H34.8 Other retinal vascular occlusions
0.897 0.103 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.897 0.103 0.000
N39.3 Stress incontinence
0.000 0.104 0.896
M72 Fibroblastic disorders
0.896 0.104 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.896 0.104 0.000
E78.6 Lipoprotein deficiency
0.892 0.108 0.000
L43.9 Lichen planus, unspecified
0.892 0.108 0.000
N34 Urethritis and urethral syndrome
0.000 0.112 0.888
L30 Other dermatitis
0.885 0.115 0.000
M10 Gout
0.884 0.116 0.000
N39.9 Disorder of urinary system, unspecified
0.000 0.117 0.883
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.881 0.119 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.870 0.130 0.000
E10.4 With neurological complications
0.870 0.130 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.137 0.863
E16.0 Drug-induced hypoglycaemia without coma
0.861 0.138 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.861 0.139 0.000
L52 Erythema nodosum
0.860 0.140 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.149 0.851
N41.0 Acute prostatitis
0.000 0.151 0.849
M31.6 Other giant cell arteritis
0.849 0.151 0.000
M62 Other disorders of muscle
0.849 0.151 0.000
L30.9 Dermatitis, unspecified
0.849 0.151 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.847 0.153 0.000
I73 Other peripheral vascular diseases
0.843 0.157 0.000
E83 Disorders of mineral metabolism
0.770 0.157 0.073
I70-I79 Diseases of arteries, arterioles and capillaries
0.843 0.157 0.000
M11.2 Other chondrocalcinosis
0.841 0.159 0.000
E78.1 Pure hyperglyceridaemia
0.838 0.162 0.000
N41.1 Chronic prostatitis
0.000 0.164 0.836
I73.9 Peripheral vascular disease, unspecified
0.834 0.166 0.000
M65-M68 Disorders of synovium and tendon
0.832 0.168 0.000
N36 Other disorders of urethra
0.000 0.170 0.830
M22.3 Other derangements of patella
0.829 0.171 0.000
H26.1 Traumatic cataract
0.826 0.174 0.000
H27 Other disorders of lens
0.820 0.180 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.814 0.186 0.000
D83 Common variable immunodeficiency
0.814 0.186 0.000
M23.9 Internal derangement of knee, unspecified
0.813 0.187 0.000
H47.3 Other disorders of optic disk
0.812 0.188 0.000
H47.2 Optic atrophy
0.811 0.189 0.000
L10-L14 Bullous disorders
0.811 0.189 0.000
I77 Other disorders of arteries and arterioles
0.809 0.191 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.807 0.193 0.000
E07 Other disorders of thyroid
0.805 0.195 0.000
L27 Dermatitis due to substances taken internally
0.803 0.197 0.000
N34.2 Other urethritis
0.000 0.200 0.800
E78.4 Other hyperlipidaemia
0.800 0.200 0.000
L53 Other erythematous conditions
0.799 0.201 0.000
N46 Male infertility
0.000 0.201 0.799
D86.8 Sarcoidosis of other and combined sites
0.799 0.201 0.000
M10.0 Idiopathic gout
0.796 0.204 0.000
M24 Other specific joint derangements
0.796 0.204 0.000
H26.4 After-cataract
0.796 0.204 0.000
I73.0 Raynaud's syndrome
0.795 0.205 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.795 0.205 0.000
D80 Immunodeficiency with predominantly antibody defects
0.793 0.207 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.791 0.209 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.791 0.209 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.786 0.214 0.000
M15 Polyarthrosis
0.786 0.214 0.000
Q50-Q56 Congenital malformations of genital organs
0.785 0.215 0.000
H31 Other disorders of choroid
0.785 0.215 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.784 0.216 0.000
E73 Lactose intolerance
0.782 0.218 0.000
M62.8 Other specified disorders of muscle
0.781 0.219 0.000
D55-D59 Haemolytic anaemias
0.781 0.219 0.000
H35 Other retinal disorders
0.778 0.222 0.000
N45 Orchitis and epididymitis
0.000 0.223 0.777
M22.2 Patellofemoral disorders
0.776 0.224 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.775 0.224 0.000
L28 Lichen simplex chronicus and prurigo
0.774 0.226 0.000
M34.1 CR(E)ST syndrome
0.773 0.227 0.000
E10.8 With unspecified complications
0.771 0.229 0.000
N30 Cystitis
0.000 0.230 0.770
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.750 0.230 0.020
D84 Other immunodeficiencies
0.769 0.231 0.000
E84 Cystic fibrosis
0.769 0.231 0.000
Chapter IX Diseases of the circulatory system
0.768 0.232 0.000
L50 Urticaria
0.767 0.233 0.000
H43.8 Other disorders of vitreous body
0.766 0.234 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.234 0.766
E20 Hypoparathyroidism
0.765 0.234 0.000
M13 Other arthritis
0.763 0.236 0.001
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.763 0.237 0.000
H34.2 Other retinal artery occlusions
0.763 0.237 0.000
H30 Chorioretinal inflammation
0.762 0.238 0.000
K50-K52 Noninfective enteritis and colitis
0.236 0.240 0.524
R30-R39 Symptoms and signs involving the urinary system
0.000 0.242 0.758
I70 Atherosclerosis
0.758 0.242 0.000
M35.7 Hypermobility syndrome
0.758 0.242 0.000
M22.8 Other disorders of patella
0.758 0.242 0.000
N36.2 Urethral caruncle
0.000 0.243 0.757
E10.5 With peripheral circulatory complications
0.757 0.243 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.757 0.243 0.000
I77.6 Arteritis, unspecified
0.756 0.244 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.754 0.246 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.247 0.753
H46 Optic neuritis
0.752 0.248 0.000
M67 Other disorders of synovium and tendon
0.751 0.249 0.000
M23.1 Discoid meniscus (congenital)
0.750 0.250 0.000
K46 Unspecified abdominal hernia
0.001 0.252 0.747
H43.2 Crystalline deposits in vitreous body
0.746 0.254 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.745 0.255 0.000
N42.2 Atrophy of prostate
0.000 0.255 0.745
M35.1 Other overlap syndromes
0.744 0.256 0.000
I77.1 Stricture of artery
0.743 0.257 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.743 0.257 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.259 0.741
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.741 0.259 0.000
K51 Ulcerative colitis
0.002 0.259 0.739
M34.9 Systemic sclerosis, unspecified
0.740 0.260 0.000
Chapter XX External causes of morbidity and mortality
0.740 0.260 0.000
E13 Other specified diabetes mellitus
0.739 0.261 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.261 0.739
E83.5 Disorders of calcium metabolism
0.735 0.261 0.004
E10.0 With coma
0.737 0.263 0.000
E23 Hypofunction and other disorders of pituitary gland
0.736 0.264 0.000
K70-K77 Diseases of liver
0.691 0.265 0.045
H35.8 Other specified retinal disorders
0.735 0.265 0.000
E16.1 Other hypoglycaemia
0.734 0.266 0.000
M32 Systemic lupus erythematosus
0.734 0.266 0.000
E74 Other disorders of carbohydrate metabolism
0.733 0.266 0.000
E10.6 With other specified complications
0.732 0.268 0.000
M23.4 Loose body in knee
0.732 0.268 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.731 0.269 0.000
N42.0 Calculus of prostate
0.000 0.270 0.730
K51.9 Ulcerative colitis, unspecified
0.000 0.270 0.730
E50-E64 Other nutritional deficiencies
0.728 0.272 0.000
M07 Psoriatic and enteropathic arthropathies
0.728 0.272 0.000
M00-M03 Infectious arthropathies
0.727 0.273 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.276 0.724
E24 Cushing's syndrome
0.722 0.277 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.722 0.278 0.000
M33 Dermatopolymyositis
0.722 0.278 0.000
M12 Other specific arthropathies
0.720 0.280 0.000
M11.9 Crystal arthropathy, unspecified
0.719 0.281 0.000
E14.1 With ketoacidosis
0.718 0.282 0.000
H52 Disorders of refraction and accommodation
0.718 0.282 0.000
M13.0 Polyarthritis, unspecified
0.717 0.282 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.717 0.283 0.000
E06 Thyroiditis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.284 0.716
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.284 0.716
R39 Other symptoms and signs involving the urinary system
0.000 0.284 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.715 0.285 0.000
M06 Other rheumatoid arthritis
0.714 0.286 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.286 0.714
N44 Torsion of testis
0.000 0.286 0.714
M10.07 Idiopathic gout (Ankle and foot)
0.713 0.287 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.712 0.288 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.712 0.288 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.288 0.712
K93 Disorders of other digestive organs in diseases classified elsewhere
0.488 0.288 0.224
Q00-Q07 Congenital malformations of the nervous system
0.712 0.288 0.000
M17.5 Other secondary gonarthrosis
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
E03.8 Other specified hypothyroidism
0.710 0.290 0.000
D82 Immunodeficiency associated with other major defects
0.710 0.290 0.000
D81 Combined immunodeficiencies
0.710 0.290 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.709 0.290 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.291 0.709
N42.3 Dysplasia of prostate
0.000 0.291 0.709
H43.9 Disorder of vitreous body, unspecified
0.707 0.293 0.000
H26.3 Drug-induced cataract
0.707 0.293 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.706 0.294 0.000
H52.1 Myopia
0.706 0.294 0.000
K75 Other inflammatory liver diseases
0.700 0.294 0.006
M10.9 Gout, unspecified
0.705 0.295 0.000
H47.1 Papilloedema, unspecified
0.704 0.296 0.000
D86.3 Sarcoidosis of skin
0.704 0.296 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.297 0.703
R33 Retention of urine
0.000 0.297 0.703
N34.3 Urethral syndrome, unspecified
0.000 0.297 0.703
K75.4 Autoimmune hepatitis
0.702 0.298 0.001
N37 Urethral disorders in diseases classified elsewhere
0.000 0.298 0.702
N33 Bladder disorders in diseases classified elsewhere
0.000 0.298 0.702
E27.3 Drug-induced adrenocortical insufficiency
0.702 0.298 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.702 0.298 0.000
H43.0 Vitreous prolapse
0.700 0.300 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.699 0.301 0.000
E32 Diseases of thymus
0.699 0.301 0.000
E31 Polyglandular dysfunction
0.699 0.301 0.000
E30 Disorders of puberty, not elsewhere classified
0.699 0.301 0.000
E25 Adrenogenital disorders
0.699 0.301 0.000
I74 Arterial embolism and thrombosis
0.699 0.301 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.699 0.301 0.000
N30.3 Trigonitis
0.000 0.301 0.699
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.697 0.303 0.000
M08 Juvenile arthritis
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.696 0.304 0.000
E77 Disorders of glycoprotein metabolism
0.696 0.304 0.000
E76 Disorders of glycosaminoglycan metabolism
0.696 0.304 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.696 0.304 0.000
E72 Other disorders of amino-acid metabolism
0.696 0.304 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.696 0.304 0.000
E70 Disorders of aromatic amino-acid metabolism
0.696 0.304 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.696 0.304 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.304 0.000
E27.5 Adrenomedullary hyperfunction
0.696 0.304 0.000
E27.0 Other adrenocortical overactivity
0.696 0.304 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.304 0.696
M76 Enthesopathies of lower limb, excluding foot
0.695 0.305 0.000
M23.0 Cystic meniscus
0.695 0.305 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.695 0.305 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.694 0.306 0.000
K90.9 Intestinal malabsorption, unspecified
0.673 0.306 0.020
D61 Other aplastic anaemias
0.693 0.306 0.000
E78.8 Other disorders of lipoprotein metabolism
0.693 0.307 0.000
M34.8 Other forms of systemic sclerosis
0.693 0.307 0.000
M67.8 Other specified disorders of synovium and tendon
0.693 0.307 0.000
E78.3 Hyperchylomicronaemia
0.693 0.307 0.000
E05.8 Other thyrotoxicosis
0.689 0.311 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.689 0.311 0.000
M35.2 Behcet's disease
0.689 0.311 0.000
E27.9 Disorder of adrenal gland, unspecified
0.688 0.311 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.312 0.688
N32.2 Vesical fistula, not elsewhere classified
0.000 0.312 0.688
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.687 0.313 0.000
D83.9 Common variable immunodeficiency, unspecified
0.687 0.313 0.000
M25 Other joint disorders, not elsewhere classified
0.686 0.314 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.685 0.314 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
K90.8 Other intestinal malabsorption
0.651 0.320 0.029
K90.3 Pancreatic steatorrhoea
0.651 0.320 0.029
K90.2 Blind loop syndrome, not elsewhere classified
0.651 0.320 0.029
K90.1 Tropical sprue
0.651 0.320 0.029
L51 Erythema multiforme
0.679 0.320 0.000
Q51 Congenital malformations of uterus and cervix
0.679 0.321 0.000
E14.8 With unspecified complications
0.679 0.321 0.000
E14.7 With multiple complications
0.679 0.321 0.000
E14.6 With other specified complications
0.679 0.321 0.000
E14.5 With peripheral circulatory complications
0.679 0.321 0.000
E14.4 With neurological complications
0.679 0.321 0.000
E14.2 Withrenal complications
0.679 0.321 0.000
E14.0 With coma
0.679 0.321 0.000
H34.9 Retinal vascular occlusion, unspecified
0.679 0.321 0.000
H34.0 Transient retinal artery occlusion
0.679 0.321 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.677 0.322 0.000
L53.8 Other specified erythematous conditions
0.677 0.323 0.000
K51.4 Pseudopolyposis of colon
0.001 0.323 0.676
N32.8 Other specified disorders of bladder
0.000 0.323 0.677
D86.0 Sarcoidosis of lung
0.676 0.324 0.000
H27.0 Aphakia
0.676 0.324 0.000
L53.0 Toxic erythema
0.675 0.325 0.000
N30.2 Other chronic cystitis
0.000 0.325 0.675
L54 Erythema in diseases classified elsewhere
0.674 0.326 0.000
L30.8 Other specified dermatitis
0.673 0.326 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.327 0.673
L27.0 Generalised skin eruption due to drugs and medicaments
0.673 0.327 0.000
E27.2 Addisonian crisis
0.672 0.328 0.000
K35-K38 Diseases of appendix
0.548 0.328 0.125
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.672 0.328 0.000
N41.3 Prostatocystitis
0.000 0.328 0.672
N41.2 Abscess of prostate
0.000 0.328 0.672
H02 Other disorders of eyelid
0.671 0.329 0.000
E40-E46 Malnutrition
0.669 0.331 0.000
X23 Contact with hornets, wasps and bees
0.666 0.334 0.000
L25 Unspecified contact dermatitis
0.665 0.335 0.000
L24 Irritant contact dermatitis
0.665 0.335 0.000
L26 Exfoliative dermatitis
0.665 0.335 0.000
L22 Diaper [napkin] dermatitis
0.665 0.335 0.000
H34.1 Central retinal artery occlusion
0.665 0.335 0.000
M14 Arthropathies in other diseases classified elsewhere
0.664 0.336 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.663 0.337 0.000
E07.9 Disorder of thyroid, unspecified
0.663 0.337 0.000
L50.0 Allergic urticaria
0.663 0.337 0.000
L42 Pityriasis rosea
0.663 0.337 0.000
M62.6 Muscle strain
0.662 0.338 0.000
M22.1 Recurrent subluxation of patella
0.661 0.339 0.000
M22.9 Disorder of patella, unspecified
0.661 0.339 0.000
L44 Other papulosquamous disorders
0.660 0.339 0.000
L41 Parapsoriasis
0.660 0.339 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.660 0.339 0.000
E29 Testicular dysfunction
0.660 0.339 0.000
L23 Allergic contact dermatitis
0.660 0.340 0.000
L13 Other bullous disorders
0.659 0.341 0.000
H47.7 Disorder of visual pathways, unspecified
0.659 0.341 0.000
H47.6 Disorders of visual cortex
0.659 0.341 0.000
H47.5 Disorders of other visual pathways
0.659 0.341 0.000
H47.4 Disorders of optic chiasm
0.659 0.341 0.000
Q53 Undescended testicle
0.659 0.341 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.659 0.341 0.000
M31.9 Necrotising vasculopathy, unspecified
0.658 0.342 0.000
M31.8 Other specified necrotising vasculopathies
0.658 0.342 0.000
M31.7 Microscopic polyangiitis
0.658 0.342 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.658 0.342 0.000
M31.2 Lethal midline granuloma
0.658 0.342 0.000
M31.1 Thrombotic microangiopathy
0.658 0.342 0.000
M31.0 Hypersensitivity angiitis
0.658 0.342 0.000
H53-H54 Visual disturbances and blindness
0.657 0.343 0.000
M22.0 Recurrent dislocation of patella
0.656 0.344 0.000
L28.0 Lichen simplex chronicus
0.656 0.344 0.000
D86.1 Sarcoidosis of lymph nodes
0.656 0.344 0.000
M17.0 Primary gonarthrosis, bilateral
0.656 0.344 0.000
E14.9 Without complications
0.656 0.344 0.000
K73 Chronic hepatitis, not elsewhere classified
0.636 0.345 0.019
L20 Atopic dermatitis
0.653 0.347 0.000
M62.0 Diastasis of muscle
0.652 0.348 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.652 0.348 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.652 0.348 0.000
M61 Calcification and ossification of muscle
0.652 0.348 0.000
H44 Disorders of globe
0.651 0.349 0.000
H02.5 Other disorders affecting eyelid function
0.651 0.349 0.000
M23.37 Other meniscus derangements-Capsular lig
0.650 0.350 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.650 0.350 0.000
M24.1 Other articular cartilage disorders
0.650 0.350 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.649 0.350 0.000
M11.8 Other specified crystal arthropathies
0.649 0.351 0.000
M11.1 Familial chondrocalcinosis
0.649 0.351 0.000
M11.0 Hydroxyapatite deposition disease
0.649 0.351 0.000
K72 Hepatic failure, not elsewhere classified
0.633 0.352 0.015
L43.3 Subacute (active) lichen planus
0.648 0.352 0.000
L43.2 Lichenoid drug reaction
0.648 0.352 0.000
L43.1 Bullous lichen planus
0.648 0.352 0.000
L43.0 Hypertrophic lichen planus
0.648 0.352 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.648 0.352 0.000
M34.0 Progressive systemic sclerosis
0.648 0.352 0.000
D64.8 Other specified anaemias
0.648 0.352 0.000
E73.9 Lactose intolerance, unspecified
0.647 0.353 0.000
N32.1 Vesicointestinal fistula
0.000 0.353 0.647
M17.3 Other posttraumatic gonarthrosis
0.646 0.354 0.000
L43.8 Other lichen planus
0.646 0.354 0.000
D59 Acquired haemolytic anaemia
0.645 0.355 0.000
E88 Other metabolic disorders
0.645 0.355 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.645 0.355 0.000
I70.0 Atherosclerosis of aorta
0.643 0.357 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.643 0.357 0.000
M72.9 Fibroblastic disorder, unspecified
0.642 0.358 0.000
M72.8 Other fibroblastic disorders
0.642 0.358 0.000
M72.6 Necrotizing fasciitis
0.642 0.358 0.000
M72.5 Fasciitis, not elsewhere classified
0.642 0.358 0.000
M72.4 Pseudosarcomatous fibromatosis
0.642 0.358 0.000
M72.3 Nodular fasciitis
0.642 0.358 0.000
M72.1 Knuckle pads
0.642 0.358 0.000
X23.9 Unspecified place
0.642 0.358 0.000
N36.3 Prolapsed urethral mucosa
0.000 0.358 0.642
I77.8 Other specified disorders of arteries and arterioles
0.642 0.358 0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.642 0.358 0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.642 0.358 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.642 0.358 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.642 0.358 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.642 0.358 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.642 0.358 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.642 0.358 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.642 0.358 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.642 0.358 0.000
K41 Femoral hernia
0.001 0.359 0.640
M20.0 Deformity of finger(s)
0.000 0.360 0.640
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.640 0.360 0.000
E78.2 Mixed hyperlipidaemia
0.639 0.361 0.000
N34.1 Nonspecific urethritis
0.000 0.363 0.637
N34.0 Urethral abscess
0.000 0.363 0.637
Q39 Congenital malformations of oesophagus
0.636 0.364 0.000
H27.1 Dislocation of lens
0.635 0.365 0.000
L30.5 Pityriasis alba
0.634 0.365 0.000
L30.4 Erythema intertrigo
0.634 0.365 0.000
L30.3 Infective dermatitis
0.634 0.365 0.000
L30.2 Cutaneous autosensitisation
0.634 0.365 0.000
L30.1 Dyshidrosis [pompholyx]
0.634 0.365 0.000
L30.0 Nummular dermatitis
0.634 0.365 0.000
N20-N23 Urolithiasis
0.000 0.366 0.634
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.634 0.366 0.000
M60 Myositis
0.634 0.366 0.000
M10.4 Other secondary gout
0.634 0.366 0.000
M10.3 Gout due to impairment of renal function
0.634 0.366 0.000
M10.2 Drug-induced gout
0.634 0.366 0.000
M10.1 Lead-induced gout
0.634 0.366 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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