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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6906662
log Bayes Factor = 78.7971
Chromosome 6   position 32,266,506  (GRCh37) Explore rs6906662 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
Chapter V Mental and behavioural disorders
0.998 0.001 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.003 0.996
F41 Other anxiety disorders
0.996 0.004 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.010 0.990
E10.3 With ophthalmic complications
0.000 0.014 0.986
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.982 0.018 0.000
F33 Recurrent depressive disorder
0.982 0.018 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.978 0.022 0.000
J32 Chronic sinusitis
0.000 0.023 0.977
# Top node
0.767 0.025 0.208
T39.1 4-Aminophenol derivatives
0.972 0.028 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.971 0.029 0.000
F60-F69 Disorders of adult personality and behaviour
0.965 0.035 0.000
T43.2 Other and unspecified antidepressants
0.965 0.035 0.000
F31 Bipolar affective disorder
0.961 0.039 0.000
J33.8 Other polyp of sinus
0.000 0.044 0.956
J32.9 Chronic sinusitis, unspecified
0.000 0.044 0.956
E10.1 With ketoacidosis
0.000 0.047 0.953
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.066 0.934
F60 Specific personality disorders
0.933 0.067 0.000
F31.9 Bipolar affective disorder, unspecified
0.929 0.071 0.000
J30 Vasomotor and allergic rhinitis
0.000 0.071 0.929
E10.4 With neurological complications
0.000 0.071 0.929
M05-M14 Inflammatory polyarthropathies
0.517 0.084 0.399
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.912 0.088 0.000
J60-J70 Lung diseases due to external agents
0.000 0.089 0.911
F30 Manic episode
0.910 0.090 0.000
J84 Other interstitial pulmonary diseases
0.000 0.094 0.906
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.901 0.099 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.099 0.901
J42 Unspecified chronic bronchitis
0.000 0.100 0.900
L40.0 Psoriasis vulgaris
0.894 0.106 0.000
F42 Obsessive-compulsive disorder
0.894 0.106 0.000
F41.2 Mixed anxiety and depressive disorder
0.887 0.113 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.524 0.119 0.357
J44 Other chronic obstructive pulmonary disease
0.000 0.123 0.877
F41.1 Generalised anxiety disorder
0.876 0.124 0.000
L40-L45 Papulosquamous disorders
0.833 0.125 0.041
T46 Poisoning by agents primarily affecting the cardiovascular system
0.871 0.129 0.000
M06 Other rheumatoid arthritis
0.155 0.130 0.716
F60.9 Personality disorder, unspecified
0.870 0.130 0.000
J30.1 Allergic rhinitis due to pollen
0.000 0.134 0.866
F44 Dissociative [conversion] disorders
0.865 0.135 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.865 0.135 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.862 0.138 0.000
E07 Other disorders of thyroid
0.000 0.141 0.859
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.143 0.857
F33.1 Recurrent depressive disorder, current episode moderate
0.855 0.145 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.145 0.855
F33.9 Recurrent depressive disorder, unspecified
0.854 0.146 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.146 0.854
F45 Somatoform disorders
0.850 0.149 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.150 0.850
T39.0 Salicylates
0.843 0.157 0.000
E06 Thyroiditis
0.000 0.158 0.842
J36 Peritonsillar abscess
0.000 0.162 0.838
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.162 0.838
F60.3 Emotionally unstable personality disorder
0.837 0.163 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.773 0.165 0.062
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.834 0.166 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.166 0.834
J32.4 Chronic pansinusitis
0.000 0.167 0.833
F32 Depressive episode
0.829 0.171 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.818 0.182 0.000
J69 Pneumonitis due to solids and liquids
0.000 0.190 0.810
J46 Status asthmaticus
0.000 0.191 0.809
E10.5 With peripheral circulatory complications
0.000 0.193 0.807
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.803 0.197 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.203 0.797
E07.9 Disorder of thyroid, unspecified
0.000 0.208 0.792
F30.9 Manic episode, unspecified
0.792 0.208 0.000
F40 Phobic anxiety disorders
0.787 0.213 0.000
F31.8 Other bipolar affective disorders
0.787 0.213 0.000
J37 Chronic laryngitis and laryngotracheitis
0.000 0.215 0.785
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.727 0.218 0.055
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.781 0.219 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.776 0.224 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.774 0.226 0.000
Chapter II Neoplasms
0.774 0.226 0.000
E14 Unspecified diabetes mellitus
0.000 0.229 0.771
T43.5 Other and unspecified antipsychotics and neuroleptics
0.769 0.231 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.769 0.231 0.000
F41.9 Anxiety disorder, unspecified
0.768 0.232 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.767 0.233 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.240 0.760
C64-C68 Malignant neoplasms of urinary tract
0.758 0.242 0.000
J40 Bronchitis, not specified as acute or chronic
0.000 0.244 0.756
M07 Psoriatic and enteropathic arthropathies
0.580 0.245 0.175
F48 Other neurotic disorders
0.751 0.249 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.750 0.250 0.000
F69 Unspecified disorder of adult personality and behaviour
0.749 0.250 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.252 0.748
E16 Other disorders of pancreatic internal secretion
0.000 0.254 0.746
F45.8 Other somatoform disorders
0.744 0.255 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.258 0.742
J69.0 Pneumonitis due to food and vomit
0.000 0.263 0.737
F99-F99 Unspecified mental disorder
0.736 0.264 0.000
F30.0 Hypomania
0.730 0.270 0.000
E06.3 Autoimmune thyroiditis
0.000 0.272 0.728
J45.0 Predominantly allergic asthma
0.000 0.274 0.726
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.275 0.725
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.725 0.275 0.000
F44.5 Dissociative convulsions
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.597 0.279 0.125
Q20-Q28 Congenital malformations of the circulatory system
0.684 0.281 0.035
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
L40.8 Other psoriasis
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
L40.1 Generalised pustular psoriasis
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E13 Other specified diabetes mellitus
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.716 0.284 0.000
F38 Other mood [affective] disorders
0.715 0.284 0.000
F39 Unspecified mood [affective] disorder
0.715 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
F41.8 Other specified anxiety disorders
0.714 0.286 0.000
F41.3 Other mixed anxiety disorders
0.714 0.286 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.714 0.286 0.000
F30.2 Mania with psychotic symptoms
0.714 0.286 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.711 0.289 0.000
F32.1 Moderate depressive episode
0.711 0.289 0.000
F34 Persistent mood [affective] disorders
0.709 0.290 0.000
F64 Gender identity disorders
0.706 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.704 0.296 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.704 0.296 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
T36 Poisoning by systemic antibiotics
0.704 0.296 0.000
F33.8 Other recurrent depressive disorders
0.704 0.296 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.704 0.296 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.704 0.296 0.000
F32.9 Depressive episode, unspecified
0.704 0.296 0.000
C51-C58 Malignant neoplasms of female genital organs
0.704 0.296 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.701 0.299 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.701 0.299 0.000
T39.4 Antirheumatics, not elsewhere classified
0.701 0.299 0.000
T39.2 Pyrazolone derivatives
0.701 0.299 0.000
J32.3 Chronic sphenoidal sinusitis
0.000 0.300 0.700
J32.1 Chronic frontal sinusitis
0.000 0.300 0.700
E03.8 Other specified hypothyroidism
0.000 0.300 0.700
Chapter XVI Certain conditions originating in the perinatal period
0.550 0.301 0.149
F44.9 Dissociative [conversion] disorder, unspecified
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.698 0.302 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.697 0.303 0.000
T43.9 Psychotropic drug, unspecified
0.696 0.304 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
T43.6 Psychostimulants with abuse potential
0.696 0.304 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.696 0.304 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.696 0.304 0.000
J30.4 Allergic rhinitis, unspecified
0.000 0.305 0.695
F68 Other disorders of adult personality and behaviour
0.692 0.308 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.692 0.308 0.000
F65 Disorders of sexual preference
0.692 0.308 0.000
F63 Habit and impulse disorders
0.692 0.308 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.692 0.308 0.000
F61 Mixed and other personality disorders
0.692 0.308 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.692 0.308 0.000
J30.3 Other allergic rhinitis
0.000 0.310 0.690
C15-C26 Malignant neoplasms of digestive organs
0.690 0.310 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.690 0.310 0.000
F31.7 Bipolar affective disorder, currently in remission
0.689 0.311 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.689 0.311 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.689 0.311 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.687 0.313 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.313 0.686
C67 Malignant neoplasm of bladder
0.685 0.315 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.316 0.684
M60-M63 Disorders of muscles
0.476 0.316 0.208
M07.3 Other psoriatic arthropathies
0.669 0.317 0.014
E14.3 With ophthalmic complications
0.000 0.317 0.683
F31.0 Bipolar affective disorder, current episode hypomanic
0.682 0.318 0.000
Q21 Congenital malformations of cardiac septa
0.668 0.320 0.012
L50-L54 Urticaria and erythema
0.650 0.321 0.029
J81 Pulmonary oedema
0.000 0.322 0.678
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.677 0.323 0.000
E40-E46 Malnutrition
0.001 0.325 0.674
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.675 0.325 0.000
C65 Malignant neoplasm of renal pelvis
0.673 0.327 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.329 0.671
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.330 0.670
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.670 0.330 0.000
F40.0 Agoraphobia
0.669 0.331 0.000
F60.8 Other specific personality disorders
0.669 0.331 0.000
F60.7 Dependent personality disorder
0.669 0.331 0.000
F60.6 Anxious [avoidant] personality disorder
0.669 0.331 0.000
F60.5 Anankastic personality disorder
0.669 0.331 0.000
F60.4 Histrionic personality disorder
0.669 0.331 0.000
F60.2 Dissocial personality disorder
0.669 0.331 0.000
F60.1 Schizoid personality disorder
0.669 0.331 0.000
F60.0 Paranoid personality disorder
0.669 0.331 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.665 0.333 0.002
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.667 0.333 0.000
J30.2 Other seasonal allergic rhinitis
0.000 0.334 0.666
J30.0 Vasomotor rhinitis
0.000 0.334 0.666
M06.0 Seronegative rheumatoid arthritis
0.079 0.334 0.587
M07.30 Other psoriatic arthropathies (Multiple sites)
0.657 0.340 0.003
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.658 0.342 0.000
M12 Other specific arthropathies
0.370 0.343 0.286
M09 Juvenile arthritis in diseases classified elsewhere
0.370 0.343 0.286
M08 Juvenile arthritis
0.370 0.343 0.286
C79 Secondary malignant neoplasm of other sites
0.654 0.346 0.000
F80-F89 Disorders of psychological development
0.654 0.346 0.000
J70 Respiratory conditions due to other external agents
0.000 0.347 0.653
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.347 0.653
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.347 0.653
J66 Airway disease due to specific organic dust
0.000 0.347 0.653
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.347 0.653
J62 Pneumoconiosis due to dust containing silica
0.000 0.347 0.653
J65 Pneumoconiosis associated with tuberculosis
0.000 0.347 0.653
J64 Unspecified pneumoconiosis
0.000 0.347 0.653
J60 Coalworker's pneumoconiosis
0.000 0.347 0.653
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.653 0.347 0.000
F30.8 Other manic episodes
0.652 0.347 0.000
F30.1 Mania without psychotic symptoms
0.652 0.347 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.652 0.348 0.000
Q21.1 Atrial septal defect
0.648 0.350 0.002
J84.8 Other specified interstitial pulmonary diseases
0.000 0.350 0.649
J84.0 Alveolar and parietoalveolar conditions
0.000 0.350 0.649
M40-M43 Deforming dorsopathies
0.451 0.353 0.197
E65-E68 Obesity and other hyperalimentation
0.000 0.354 0.646
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.646 0.354 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.646 0.354 0.000
T42.3 Barbiturates
0.646 0.354 0.000
T42.2 Succinimides and oxazolidinediones
0.646 0.354 0.000
T42.1 Iminostilbenes
0.646 0.354 0.000
T42.0 Hydantoin derivatives
0.646 0.354 0.000
M05 Seropositive rheumatoid arthritis
0.269 0.355 0.376
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.644 0.356 0.000
M14 Arthropathies in other diseases classified elsewhere
0.360 0.356 0.284
F42.8 Other obsessive-compulsive disorders
0.641 0.359 0.000
F42.2 Mixed obsessional thoughts and acts
0.641 0.359 0.000
F42.1 Predominantly compulsive acts [obsessional rituals]
0.641 0.359 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.641 0.359 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.639 0.361 0.000
Chapter VI Diseases of the nervous system
0.443 0.366 0.191
T42.4 Benzodiazepines
0.633 0.367 0.000
M11 Other crystal arthropathies
0.369 0.368 0.263
S20-S29 Injuries to the thorax
0.632 0.368 0.000
J37.0 Chronic laryngitis
0.000 0.370 0.630
L60-L75 Disorders of skin appendages
0.618 0.370 0.012
C67.4 Posterior wall of bladder
0.629 0.371 0.000
L44 Other papulosquamous disorders
0.597 0.373 0.030
L41 Parapsoriasis
0.597 0.373 0.030
L45 Papulosquamous disorders in diseases classified elsewhere
0.597 0.373 0.030
L42 Pityriasis rosea
0.597 0.373 0.030
F43 Reaction to severe stress, and adjustment disorders
0.626 0.373 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.626 0.374 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.626 0.374 0.000
J32.8 Other chronic sinusitis
0.000 0.374 0.626
M35 Other systemic involvement of connective tissue
0.000 0.375 0.625
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.624 0.375 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.624 0.375 0.000
T46.7 Peripheral vasodilators
0.624 0.375 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.624 0.375 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.624 0.375 0.000
T46.1 Calcium-channel blockers
0.624 0.375 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.624 0.375 0.000
M06.8 Other specified rheumatoid arthritis
0.111 0.376 0.513
M06.4 Inflammatory polyarthropathy
0.111 0.376 0.513
M06.2 Rheumatoid bursitis
0.111 0.376 0.513
M06.1 Adult-onset Still's disease
0.111 0.376 0.513
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.377 0.623
Q80-Q89 Other congenital malformations
0.593 0.377 0.030
C56 Malignant neoplasm of ovary
0.622 0.378 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.379 0.621
M00-M03 Infectious arthropathies
0.364 0.380 0.256
F44.8 Other dissociative [conversion] disorders
0.620 0.380 0.000
F44.7 Mixed dissociative [conversion] disorders
0.620 0.380 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.620 0.380 0.000
F44.4 Dissociative motor disorders
0.620 0.380 0.000
F44.3 Trance and possession disorders
0.620 0.380 0.000
F44.2 Dissociative stupor
0.620 0.380 0.000
F44.1 Dissociative fugue
0.620 0.380 0.000
F44.0 Dissociative amnesia
0.620 0.380 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.620 0.380 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.620 0.380 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.620 0.380 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.620 0.380 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.620 0.380 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.620 0.380 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.620 0.380 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.620 0.380 0.000
T44.0 Anticholinesterase agents
0.620 0.380 0.000
M35.3 Polymyalgia rheumatica
0.000 0.381 0.619
T50.8 Diagnostic agents
0.618 0.382 0.000
T50.7 Analeptics and opioid receptor antagonists
0.618 0.382 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.618 0.382 0.000
T50.5 Appetite depressants
0.618 0.382 0.000
T50.4 Drugs affecting uric acid metabolism
0.618 0.382 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.618 0.382 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.618 0.382 0.000
T50.1 Loop [high-ceiling] diuretics
0.618 0.382 0.000
T50.0 Mineralocorticoids and their antagonists
0.618 0.382 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.618 0.382 0.000
E07.1 Dyshormogenetic goitre
0.000 0.384 0.616
E07.0 Hypersecretion of calcitonin
0.000 0.384 0.616
T47.1 Other antacids and anti-gastric-secretion drugs
0.613 0.387 0.000
F45.9 Somatoform disorder, unspecified
0.610 0.390 0.000
F45.4 Persistent somatoform pain disorder
0.610 0.390 0.000
F45.3 Somatoform autonomic dysfunction
0.610 0.390 0.000
F45.2 Hypochondriacal disorder
0.610 0.390 0.000
F45.1 Undifferentiated somatoform disorder
0.610 0.390 0.000
F45.0 Somatisation disorder
0.610 0.390 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.390 0.609
C25 Malignant neoplasm of pancreas
0.610 0.390 0.000
M91-M94 Chondropathies
0.386 0.392 0.222
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.607 0.393 0.000
E06.9 Thyroiditis, unspecified
0.000 0.396 0.603
E06.5 Other chronic thyroiditis
0.000 0.396 0.603
E06.4 Drug-induced thyroiditis
0.000 0.396 0.603
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.396 0.603
E06.1 Subacute thyroiditis
0.000 0.396 0.603
E06.0 Acute thyroiditis
0.000 0.396 0.603
K90 Intestinal malabsorption
0.000 0.399 0.601
L10-L14 Bullous disorders
0.554 0.401 0.045
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.597 0.403 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.595 0.405 0.000
F32.8 Other depressive episodes
0.594 0.406 0.000
M20-M25 Other joint disorders
0.002 0.408 0.590
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.355 0.409 0.237
C51 Malignant neoplasm of vulva
0.591 0.409 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.553 0.409 0.037
C73 Malignant neoplasm of thyroid gland
0.590 0.410 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.555 0.410 0.035
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.589 0.411 0.000
S10-S19 Injuries to the neck
0.588 0.412 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.587 0.413 0.000
M06.3 Rheumatoid nodule
0.120 0.413 0.467
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.585 0.415 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.585 0.415 0.000
C66 Malignant neoplasm of ureter
0.582 0.418 0.000
J69.8 Pneumonitis due to other solids and liquids
0.000 0.419 0.581
J69.1 Pneumonitis due to oils and essences
0.000 0.419 0.581
C90 Multiple myeloma and malignant plasma cell neoplasms
0.580 0.420 0.000
S32 Fracture of lumbar spine and pelvis
0.578 0.422 0.000
L71 Rosacea
0.571 0.422 0.006
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.423 0.577
T38.9 Other and unspecified hormone antagonists
0.576 0.424 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.576 0.424 0.000
T38.7 Androgens and anabolic congeners
0.576 0.424 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.576 0.424 0.000
T38.5 Other oestrogens and progestogens
0.576 0.424 0.000
T38.4 Oral contraceptives
0.576 0.424 0.000
T38.2 Antithyroid drugs
0.576 0.424 0.000
T38.1 Thyroid hormones and substitutes
0.576 0.424 0.000
T38.0 Glucocorticoids and synthetic analogues
0.576 0.424 0.000
F48.0 Neurasthenia
0.574 0.426 0.000
C67.5 Bladder neck
0.574 0.426 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.428 0.572
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.571 0.428 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.510 0.428 0.062
L53 Other erythematous conditions
0.556 0.429 0.015
C91 Lymphoid leukaemia
0.569 0.431 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.534 0.431 0.035
Q21.0 Ventricular septal defect
0.561 0.432 0.006
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.567 0.433 0.000
J34 Other disorders of nose and nasal sinuses
0.000 0.433 0.567
M86-M90 Other osteopathies
0.370 0.434 0.196
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.566 0.434 0.000
Q00-Q07 Congenital malformations of the nervous system
0.528 0.435 0.037
F40.9 Phobic anxiety disorder, unspecified
0.564 0.435 0.000
F40.8 Other phobic anxiety disorders
0.564 0.435 0.000
F40.1 Social phobias
0.564 0.435 0.000
C12 Malignant neoplasm of pyriform sinus
0.564 0.436 0.000
J37.1 Chronic laryngotracheitis
0.000 0.437 0.563
J32.2 Chronic ethmoidal sinusitis
0.000 0.438 0.562
Q35-Q37 Cleft lip and cleft palate
0.521 0.440 0.039
Q30-Q34 Congenital malformations of the respiratory system
0.521 0.440 0.039
C76 Malignant neoplasm of other and ill-defined sites
0.560 0.440 0.000
C21 Malignant neoplasm of anus and anal canal
0.560 0.440 0.000
C71 Malignant neoplasm of brain
0.559 0.441 0.000
M22 Disorders of patella
0.001 0.442 0.557
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.556 0.444 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.555 0.445 0.000
T33-T35 Frostbite
0.555 0.445 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.555 0.445 0.000
T00-T07 Injuries involving multiple body regions
0.555 0.445 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.555 0.445 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.554 0.446 0.000
M10 Gout
0.285 0.446 0.269
C53 Malignant neoplasm of cervix uteri
0.553 0.447 0.000
E14.8 With unspecified complications
0.000 0.447 0.553
E14.7 With multiple complications
0.000 0.447 0.553
E14.6 With other specified complications
0.000 0.447 0.553
E14.5 With peripheral circulatory complications
0.000 0.447 0.553
E14.4 With neurological complications
0.000 0.447 0.553
E14.2 Withrenal complications
0.000 0.447 0.553
E14.1 With ketoacidosis
0.000 0.447 0.553
E14.0 With coma
0.000 0.447 0.553
T51 Toxic effect of alcohol
0.552 0.447 0.000
C67.1 Dome of bladder
0.551 0.449 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.550 0.450 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.550 0.450 0.000
T47.7 Emetics
0.550 0.450 0.000
T47.6 Antidiarrhoeal drugs
0.550 0.450 0.000
T47.5 Digestants
0.550 0.450 0.000
T47.4 Other laxatives
0.550 0.450 0.000
T47.3 Saline and osmotic laxatives
0.550 0.450 0.000
T47.2 Stimulant laxatives
0.550 0.450 0.000
T47.0 Histamine H(2)-receptor antagonists
0.550 0.450 0.000
M45-M49 Spondylopathies
0.364 0.451 0.185
F99 Mental disorder, not otherwise specified
0.548 0.452 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.548 0.452 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.540 0.452 0.008
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.548 0.452 0.000
Q50-Q56 Congenital malformations of genital organs
0.514 0.452 0.034
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.547 0.453 0.000
J35 Chronic diseases of tonsils and adenoids
0.000 0.453 0.546
M20 Acquired deformities of fingers and toes
0.000 0.454 0.546
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.538 0.454 0.008
L71.9 Rosacea, unspecified
0.544 0.454 0.002
T79-T79 Certain early complications of trauma
0.544 0.456 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.543 0.456 0.000
M62 Other disorders of muscle
0.441 0.457 0.102
M07.6 Other enteropathic arthropathies
0.416 0.459 0.125
M07.5 Arthropathy in ulcerative colitis
0.416 0.459 0.125
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.416 0.459 0.125
M07.2 Psoriatic spondylitis
0.416 0.459 0.125
M07.1 Arthritis mutilans
0.416 0.459 0.125
M07.0 Distal interphalangeal psoriatic arthropathy
0.416 0.459 0.125
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.541 0.459 0.000
F48.9 Neurotic disorder, unspecified
0.539 0.461 0.000
F48.8 Other specified neurotic disorders
0.539 0.461 0.000
F48.1 Depersonalisation-derealisation syndrome
0.539 0.461 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.462 0.538
C13 Malignant neoplasm of hypopharynx
0.537 0.463 0.000
F43.0 Acute stress reaction
0.536 0.463 0.000
S90-S99 Injuries to the ankle and foot
0.535 0.465 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.465 0.535
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.465 0.535
E16.4 Abnormal secretion of gastrin
0.000 0.465 0.535
E16.3 Increased secretion of glucagon
0.000 0.465 0.535
E16.1 Other hypoglycaemia
0.000 0.465 0.535
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.465 0.535
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.001 0.465 0.534
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.038 0.465 0.497
L52 Erythema nodosum
0.517 0.465 0.017
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.534 0.465 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.533 0.467 0.000
J96 Respiratory failure, not elsewhere classified
0.000 0.468 0.532
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.532 0.468 0.000
C52 Malignant neoplasm of vagina
0.532 0.468 0.000
C05 Malignant neoplasm of palate
0.531 0.469 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.471 0.529
J31.2 Chronic pharyngitis
0.000 0.472 0.528
C17 Malignant neoplasm of small intestine
0.525 0.475 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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