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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6911777
log Bayes Factor = 42.3826
Chromosome 6   position 32,409,996  (GRCh37) Explore rs6911777 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
J20-J22 Other acute lower respiratory infections
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.002 0.998
J22 Unspecified acute lower respiratory infection
0.000 0.003 0.997
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.003 0.997
E03.9 Hypothyroidism, unspecified
0.000 0.003 0.997
H36.0 Diabetic retinopathy
0.000 0.003 0.997
H36 Retinal disorders in diseases classified elsewhere
0.000 0.004 0.996
H30-H36 Disorders of choroid and retina
0.000 0.004 0.996
L40.9 Psoriasis, unspecified
0.000 0.005 0.995
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.006 0.994
L40.5 Arthropathic psoriasis
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.009 0.991
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.009 0.991
M35.3 Polymyalgia rheumatica
0.000 0.011 0.989
D50-D53 Nutritional anaemias
0.000 0.011 0.989
M35 Other systemic involvement of connective tissue
0.000 0.012 0.988
M05 Seropositive rheumatoid arthritis
0.000 0.013 0.987
E10.1 With ketoacidosis
0.000 0.013 0.987
D50 Iron deficiency anaemia
0.000 0.015 0.985
L20-L30 Dermatitis and eczema
0.000 0.017 0.983
M20-M25 Other joint disorders
0.000 0.018 0.982
D50.8 Other iron deficiency anaemias
0.000 0.019 0.981
H02 Other disorders of eyelid
0.000 0.021 0.979
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.022 0.978
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.024 0.976
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.030 0.970
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.040 0.960
J30-J39 Other diseases of upper respiratory tract
0.000 0.041 0.959
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.045 0.955
H04 Disorders of lachrymal system
0.000 0.047 0.953
J33 Nasal polyp
0.000 0.050 0.950
E11 Non-insulin-dependent diabetes mellitus
0.000 0.051 0.949
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.051 0.949
J80 Adult respiratory distress syndrome
0.000 0.052 0.948
H02.1 Ectropion of eyelid
0.000 0.055 0.945
M35.0 Sicca syndrome [Sjogren]
0.000 0.056 0.944
M07 Psoriatic and enteropathic arthropathies
0.000 0.067 0.933
L29 Pruritus
0.000 0.067 0.933
E11.3 With ophthalmic complications
0.000 0.067 0.933
J84 Other interstitial pulmonary diseases
0.000 0.069 0.931
J33.0 Polyp of nasal cavity
0.000 0.071 0.929
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.073 0.927
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.074 0.926
N48 Other disorders of penis
0.906 0.094 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.095 0.905
E50-E64 Other nutritional deficiencies
0.000 0.098 0.902
N48.6 Balanitis xerotica obliterans
0.901 0.099 0.000
N40-N51 Diseases of male genital organs
0.897 0.103 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.107 0.893
M07.3 Other psoriatic arthropathies
0.000 0.114 0.886
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.116 0.884
E10.4 With neurological complications
0.000 0.118 0.882
H02.0 Entropion and trichiasis of eyelid
0.000 0.121 0.879
E27 Other disorders of adrenal gland
0.000 0.122 0.878
L81 Other disorders of pigmentation
0.000 0.132 0.868
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.132 0.868
M06.0 Seronegative rheumatoid arthritis
0.000 0.132 0.868
N45 Orchitis and epididymitis
0.868 0.132 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.136 0.864
L57.0 Actinic keratosis
0.000 0.140 0.860
L30 Other dermatitis
0.000 0.141 0.859
L29.0 Pruritus ani
0.000 0.141 0.859
H02.4 Ptosis of eyelid
0.000 0.143 0.857
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.145 0.855
J32 Chronic sinusitis
0.000 0.148 0.852
E10.2 With renal complications
0.000 0.149 0.851
L85 Other epidermal thickening
0.000 0.149 0.851
N41 Inflammatory diseases of prostate
0.849 0.151 0.000
N48.0 Leukoplakia of penis
0.846 0.154 0.000
J35 Chronic diseases of tonsils and adenoids
0.000 0.156 0.844
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.844 0.156 0.000
N50 Other disorders of male genital organs
0.840 0.160 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.163 0.837
L81.4 Other melanin hyperpigmentation
0.000 0.163 0.837
E27.1 Primary adrenocortical insufficiency
0.000 0.165 0.835
D51 Vitamin B12 deficiency anaemia
0.000 0.166 0.834
M31 Other necrotising vasculopathies
0.000 0.170 0.830
M34 Systemic sclerosis
0.000 0.172 0.828
J35.0 Chronic tonsillitis
0.000 0.173 0.827
J20 Acute bronchitis
0.000 0.174 0.826
E06 Thyroiditis
0.000 0.177 0.823
N48.8 Other specified disorders of penis
0.821 0.179 0.000
J33.9 Nasal polyp, unspecified
0.000 0.180 0.820
E55 Vitamin D deficiency
0.000 0.182 0.818
H04.2 Epiphora
0.000 0.188 0.812
E14 Unspecified diabetes mellitus
0.000 0.188 0.812
E11.1 With ketoacidosis
0.000 0.189 0.811
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.190 0.810
N50.8 Other specified disorders of male genital organs
0.808 0.192 0.000
L28 Lichen simplex chronicus and prurigo
0.000 0.193 0.807
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.194 0.806
D50.9 Iron deficiency anaemia, unspecified
0.000 0.199 0.801
D60-D64 Aplastic and other anaemias
0.000 0.200 0.800
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.204 0.796
M60-M63 Disorders of muscles
0.000 0.207 0.792
L83 Acanthosis nigricans
0.000 0.208 0.792
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.212 0.788
N47 Redundant prepuce, phimosis and paraphimosis
0.787 0.213 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.213 0.787
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.219 0.781
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.219 0.781
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.220 0.780
N48.9 Disorder of penis, unspecified
0.778 0.222 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.225 0.775
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.229 0.771
L82 Seborrhoeic keratosis
0.000 0.234 0.766
H02.5 Other disorders affecting eyelid function
0.000 0.236 0.764
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.236 0.764
M06.3 Rheumatoid nodule
0.000 0.238 0.762
D52 Folate deficiency anaemia
0.000 0.240 0.760
E55.9 Vitamin D deficiency, unspecified
0.000 0.242 0.758
N41.0 Acute prostatitis
0.758 0.242 0.000
J33.8 Other polyp of sinus
0.000 0.244 0.756
J81 Pulmonary oedema
0.000 0.245 0.755
H05 Disorders of orbit
0.000 0.247 0.753
L93 Lupus erythematosus
0.000 0.248 0.752
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.249 0.751
N41.9 Inflammatory disease of prostate, unspecified
0.750 0.250 0.000
L29.9 Pruritus, unspecified
0.000 0.250 0.750
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.251 0.749
L29.2 Pruritus vulvae
0.000 0.253 0.747
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.253 0.747
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.255 0.745
E53 Deficiency of other B group vitamins
0.000 0.256 0.744
L80 Vitiligo
0.000 0.259 0.741
J32.8 Other chronic sinusitis
0.000 0.261 0.739
L85.8 Other specified epidermal thickening
0.000 0.261 0.739
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.261 0.739
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.261 0.739
H55-H59 Other disorders of eye and adnexa
0.000 0.262 0.738
H02.9 Disorder of eyelid, unspecified
0.000 0.262 0.738
D61 Other aplastic anaemias
0.000 0.263 0.737
J00-J06 Acute upper respiratory infections
0.000 0.265 0.735
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.265 0.735
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.268 0.732
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.268 0.731
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.728 0.272 0.000
L30.9 Dermatitis, unspecified
0.000 0.272 0.728
Chapter I Certain infectious and parasitic diseases
0.000 0.273 0.727
E11.2 With renal complications
0.000 0.275 0.725
L20 Atopic dermatitis
0.000 0.276 0.724
C44 Other malignant neoplasms of skin
0.000 0.278 0.722
H02.6 Xanthelasma of eyelid
0.000 0.279 0.721
L27 Dermatitis due to substances taken internally
0.000 0.280 0.720
E07 Other disorders of thyroid
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.5 With peripheral circulatory complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
J21 Acute bronchiolitis
0.000 0.284 0.716
H53-H54 Visual disturbances and blindness
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E03.1 Congenital hypothyroidism without goitre
0.000 0.285 0.715
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.285 0.715
C44.1 Skin of eyelid, including canthus
0.000 0.285 0.715
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.286 0.714
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.714
H30 Chorioretinal inflammation
0.000 0.286 0.714
E11.8 With unspecified complications
0.000 0.287 0.713
E27.8 Other specified disorders of adrenal gland
0.000 0.289 0.711
N50.9 Disorder of male genital organs, unspecified
0.710 0.290 0.000
L40.0 Psoriasis vulgaris
0.000 0.291 0.709
D53 Other nutritional anaemias
0.000 0.291 0.709
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.292 0.708
M35.8 Other specified systemic involvement of connective tissue
0.000 0.292 0.708
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.292 0.708
M35.5 Multifocal fibrosclerosis
0.000 0.292 0.708
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.292 0.708
M35.2 Behcet's disease
0.000 0.292 0.708
M35.1 Other overlap syndromes
0.000 0.292 0.708
E11.4 With neurological complications
0.000 0.292 0.708
M05.8 Other seropositive rheumatoid arthritis
0.000 0.292 0.708
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.292 0.708
M05.2 Rheumatoid vasculitis
0.000 0.292 0.708
M05.1 Rheumatoid lung disease
0.000 0.292 0.708
M05.0 Felty's syndrome
0.000 0.292 0.708
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.293 0.707
D50.1 Sideropenic dysphagia
0.000 0.293 0.706
H04.4 Chronic inflammation of lachrymal passages
0.000 0.295 0.705
L25 Unspecified contact dermatitis
0.000 0.295 0.705
L24 Irritant contact dermatitis
0.000 0.295 0.705
L23 Allergic contact dermatitis
0.000 0.295 0.705
L21 Seborrhoeic dermatitis
0.000 0.295 0.705
L26 Exfoliative dermatitis
0.000 0.295 0.705
L22 Diaper [napkin] dermatitis
0.000 0.295 0.705
M31.3 Wegener's granulomatosis
0.000 0.296 0.704
M32 Systemic lupus erythematosus
0.000 0.296 0.704
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.296 0.704
M06.4 Inflammatory polyarthropathy
0.000 0.296 0.704
J20.9 Acute bronchitis, unspecified
0.000 0.297 0.703
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.298 0.702
N48.4 Impotence of organic origin
0.702 0.298 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.299 0.701
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.299 0.701
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.299 0.701
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.299 0.701
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.299 0.701
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.299 0.701
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.299 0.701
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.299 0.701
C44.7 Skin of lower limb, including hip
0.000 0.301 0.699
L42 Pityriasis rosea
0.000 0.302 0.698
H04.9 Disorder of lachrymal system, unspecified
0.000 0.302 0.698
H46 Optic neuritis
0.000 0.304 0.696
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.304 0.696
C44.3 Skin of other and unspecified parts of face
0.000 0.305 0.695
L30.8 Other specified dermatitis
0.000 0.306 0.694
D61.9 Aplastic anaemia, unspecified
0.000 0.307 0.693
E10.6 With other specified complications
0.000 0.309 0.691
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.310 0.690
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.312 0.688
L87 Transepidermal elimination disorders
0.000 0.312 0.688
L88 Pyoderma gangrenosum
0.000 0.312 0.688
L86 Keratoderma in diseases classified elsewhere
0.000 0.312 0.688
E06.3 Autoimmune thyroiditis
0.000 0.314 0.686
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.315 0.684
L58 Radiodermatitis
0.000 0.315 0.684
L55 Sunburn
0.000 0.315 0.684
H04.8 Other disorders of lachrymal system
0.000 0.316 0.684
H04.6 Other changes in lachrymal passages
0.000 0.316 0.684
H04.0 Dacryoadenitis
0.000 0.316 0.684
M34.9 Systemic sclerosis, unspecified
0.000 0.317 0.683
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.317 0.683
L85.9 Epidermal thickening, unspecified
0.000 0.318 0.682
L28.0 Lichen simplex chronicus
0.000 0.318 0.681
J33.1 Polypoid sinus degeneration
0.000 0.319 0.681
L94 Other localised connective tissue disorders
0.000 0.319 0.681
E11.7 With multiple complications
0.000 0.320 0.680
M35.7 Hypermobility syndrome
0.000 0.320 0.679
E27.9 Disorder of adrenal gland, unspecified
0.000 0.322 0.678
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.325 0.675
L29.8 Other pruritus
0.000 0.326 0.674
J32.9 Chronic sinusitis, unspecified
0.000 0.329 0.671
M07.6 Other enteropathic arthropathies
0.000 0.331 0.669
M07.5 Arthropathy in ulcerative colitis
0.000 0.331 0.669
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.331 0.669
M07.2 Psoriatic spondylitis
0.000 0.331 0.669
M07.1 Arthritis mutilans
0.000 0.331 0.669
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.331 0.669
L29.3 Anogenital pruritus, unspecified
0.000 0.331 0.669
L29.1 Pruritus scroti
0.000 0.331 0.669
L84 Corns and callosities
0.000 0.331 0.669
J84.8 Other specified interstitial pulmonary diseases
0.000 0.333 0.667
J84.0 Alveolar and parietoalveolar conditions
0.000 0.333 0.667
E05.8 Other thyrotoxicosis
0.000 0.334 0.666
M30 Polyarteritis nodosa and related conditions
0.000 0.335 0.665
D55-D59 Haemolytic anaemias
0.000 0.335 0.665
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.336 0.664
L57.5 Actinic granuloma
0.000 0.336 0.664
L57.3 Poikiloderma of Civatte
0.000 0.336 0.664
L57.2 Cutis rhomboidalis nuchae
0.000 0.336 0.664
L57.1 Actinic reticuloid
0.000 0.336 0.664
J00 Acute nasopharyngitis [common cold]
0.000 0.336 0.664
M00-M03 Infectious arthropathies
0.000 0.337 0.663
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.337 0.663
M14 Arthropathies in other diseases classified elsewhere
0.000 0.339 0.660
N48.2 Other inflammatory disorders of penis
0.660 0.339 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.342 0.658
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.344 0.655
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.345 0.655
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.345 0.655
E28 Ovarian dysfunction
0.000 0.346 0.654
H01 Other inflammation of eyelid
0.000 0.346 0.654
L10-L14 Bullous disorders
0.000 0.347 0.653
M33 Dermatopolymyositis
0.000 0.348 0.652
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.651 0.349 0.000
E29 Testicular dysfunction
0.000 0.349 0.650
N48.5 Ulcer of penis
0.649 0.351 0.000
N48.3 Priapism
0.649 0.351 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.351 0.649
M34.1 CR(E)ST syndrome
0.000 0.352 0.648
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.353 0.647
E63 Other nutritional deficiencies
0.000 0.353 0.647
E56 Other vitamin deficiencies
0.000 0.353 0.647
E51 Thiamine deficiency
0.000 0.353 0.647
E50 Vitamin A deficiency
0.000 0.353 0.647
E60 Dietary zinc deficiency
0.000 0.353 0.647
E59 Dietary selenium deficiency
0.000 0.353 0.647
E58 Dietary calcium deficiency
0.000 0.353 0.647
E54 Ascorbic acid deficiency
0.000 0.353 0.647
E52 Niacin deficiency [pellagra]
0.000 0.353 0.647
M80-M85 Disorders of bone density and structure
0.000 0.353 0.647
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.354 0.646
M62 Other disorders of muscle
0.000 0.354 0.646
J32.0 Chronic maxillary sinusitis
0.000 0.355 0.645
N51 Disorders of male genital organs in diseases classified elsewhere
0.643 0.357 0.000
N44 Torsion of testis
0.643 0.357 0.000
E14.3 With ophthalmic complications
0.000 0.357 0.643
E04 Other non-toxic goitre
0.000 0.358 0.642
E11.0 With coma
0.000 0.358 0.642
M91-M94 Chondropathies
0.000 0.358 0.642
J09-J18 Influenza and pneumonia
0.000 0.359 0.641
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.359 0.640
E32 Diseases of thymus
0.000 0.359 0.640
E31 Polyglandular dysfunction
0.000 0.359 0.640
E30 Disorders of puberty, not elsewhere classified
0.000 0.359 0.640
E20 Hypoparathyroidism
0.000 0.359 0.640
E70-E90 Metabolic disorders
0.000 0.363 0.637
H02.2 Lagophthalmos
0.000 0.364 0.636
M07.38 Other psoriatic arthropathies (Other)
0.000 0.365 0.635
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.365 0.635
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.365 0.635
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.365 0.635
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.365 0.635
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.365 0.635
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.365 0.635
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.365 0.635
N42 Other disorders of prostate
0.635 0.365 0.000
M11 Other crystal arthropathies
0.000 0.365 0.635
J31.2 Chronic pharyngitis
0.000 0.365 0.635
N50.0 Atrophy of testis
0.634 0.366 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.366 0.634
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.366 0.634
L98.5 Mucinosis of skin
0.000 0.366 0.634
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.366 0.634
L98.1 Factitial dermatitis
0.000 0.366 0.634
H00 Hordeolum and chalazion
0.000 0.368 0.632
E53.8 Deficiency of other specified B group vitamins
0.000 0.369 0.631
M31.6 Other giant cell arteritis
0.000 0.369 0.631
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.369 0.631
E23 Hypofunction and other disorders of pituitary gland
0.000 0.369 0.630
E27.5 Adrenomedullary hyperfunction
0.000 0.370 0.630
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.370 0.630
E27.2 Addisonian crisis
0.000 0.370 0.630
E27.0 Other adrenocortical overactivity
0.000 0.370 0.630
B35-B49 Mycoses
0.000 0.370 0.630
E14.9 Without complications
0.000 0.371 0.629
N41.1 Chronic prostatitis
0.627 0.373 0.000
H02.3 Blepharochalasis
0.000 0.374 0.626
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.377 0.623
L81.7 Pigmented purpuric dermatosis
0.000 0.378 0.622
L81.6 Other disorders of diminished melanin formation
0.000 0.378 0.622
L81.5 Leukoderma, not elsewhere classified
0.000 0.378 0.622
L81.3 Cafe au lait spots
0.000 0.378 0.622
L81.2 Freckles
0.000 0.378 0.622
L81.1 Chloasma
0.000 0.378 0.622
L81.0 Postinflammatory hyperpigmentation
0.000 0.378 0.622
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.378 0.622
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.378 0.622
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.378 0.622
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.378 0.622
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.378 0.622
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.378 0.622
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.378 0.622
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.378 0.622
J32.4 Chronic pansinusitis
0.000 0.378 0.622
E26 Hyperaldosteronism
0.000 0.381 0.619
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.383 0.617
M80 Osteoporosis with pathological fracture
0.000 0.384 0.616
L30.5 Pityriasis alba
0.000 0.384 0.616
L30.4 Erythema intertrigo
0.000 0.384 0.616
L30.3 Infective dermatitis
0.000 0.384 0.616
L30.2 Cutaneous autosensitisation
0.000 0.384 0.616
L30.1 Dyshidrosis [pompholyx]
0.000 0.384 0.616
L30.0 Nummular dermatitis
0.000 0.384 0.616
D80-D89 Certain disorders involving the immune mechanism
0.000 0.384 0.616
H34 Retinal vascular occlusions
0.000 0.388 0.612
J32.3 Chronic sphenoidal sinusitis
0.000 0.389 0.611
Chapter II Neoplasms
0.000 0.389 0.611
L85.3 Xerosis cutis
0.000 0.390 0.610
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.390 0.610
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.390 0.610
L85.0 Acquired ichthyosis
0.000 0.390 0.610
L43 Lichen planus
0.000 0.390 0.610
C44.6 Skin of upper limb, including shoulder
0.000 0.390 0.610
N46 Male infertility
0.609 0.391 0.000
N41.8 Other inflammatory diseases of prostate
0.609 0.391 0.000
N41.3 Prostatocystitis
0.609 0.391 0.000
N41.2 Abscess of prostate
0.609 0.391 0.000
J32.1 Chronic frontal sinusitis
0.000 0.391 0.609
E06.9 Thyroiditis, unspecified
0.000 0.391 0.608
N49.2 Inflammatory disorders of scrotum
0.607 0.393 0.000
L98.0 Pyogenic granuloma
0.000 0.394 0.606
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.394 0.605
E40-E46 Malnutrition
0.000 0.395 0.604
L93.0 Discoid lupus erythematosus
0.000 0.396 0.604
B37 Candidiasis
0.000 0.397 0.603
L81.8 Other specified disorders of pigmentation
0.000 0.398 0.602
H05.0 Acute inflammation of orbit
0.000 0.401 0.599
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.402 0.598
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.402 0.598
D51.2 Transcobalamin II deficiency
0.000 0.402 0.598
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.402 0.598
D52.9 Folate deficiency anaemia, unspecified
0.000 0.403 0.596
M31.9 Necrotising vasculopathy, unspecified
0.000 0.405 0.595
M31.8 Other specified necrotising vasculopathies
0.000 0.405 0.595
M31.7 Microscopic polyangiitis
0.000 0.405 0.595
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.405 0.595
M31.2 Lethal midline granuloma
0.000 0.405 0.595
M31.1 Thrombotic microangiopathy
0.000 0.405 0.595
M31.0 Hypersensitivity angiitis
0.000 0.405 0.595
M34.8 Other forms of systemic sclerosis
0.000 0.406 0.593
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.406 0.593
M34.0 Progressive systemic sclerosis
0.000 0.406 0.593
B37.8 Candidiasis of other sites
0.000 0.407 0.593
L57.4 Cutis laxa senilis
0.000 0.407 0.593
E03.8 Other specified hypothyroidism
0.000 0.407 0.592
J20.8 Acute bronchitis due to other specified organisms
0.000 0.407 0.592
J20.7 Acute bronchitis due to echovirus
0.000 0.407 0.592
J20.6 Acute bronchitis due to rhinovirus
0.000 0.407 0.592
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.407 0.592
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.407 0.592
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.407 0.592
J20.2 Acute bronchitis due to streptococcus
0.000 0.407 0.592
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.407 0.592
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.407 0.592
M06.34 Rheumatoid nodule (Hand)
0.000 0.409 0.591
E06.5 Other chronic thyroiditis
0.000 0.409 0.590
E06.4 Drug-induced thyroiditis
0.000 0.409 0.590
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.409 0.590
E06.1 Subacute thyroiditis
0.000 0.409 0.590
E06.0 Acute thyroiditis
0.000 0.409 0.590
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.410 0.590
H04.1 Other disorders of lachrymal gland
0.000 0.410 0.590
J32.2 Chronic ethmoidal sinusitis
0.000 0.410 0.590
D62 Acute posthaemorrhagic anaemia
0.000 0.410 0.590
J37 Chronic laryngitis and laryngotracheitis
0.000 0.411 0.589
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.412 0.588
J31.0 Chronic rhinitis
0.000 0.413 0.587
E55.0 Rickets, active
0.000 0.413 0.587
E24 Cushing's syndrome
0.000 0.413 0.586
J01 Acute sinusitis
0.000 0.414 0.586
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.415 0.585
A63.0 Anogenital (venereal) warts
0.000 0.416 0.584
E14.8 With unspecified complications
0.000 0.418 0.582
E14.7 With multiple complications
0.000 0.418 0.582
E14.6 With other specified complications
0.000 0.418 0.582
E14.5 With peripheral circulatory complications
0.000 0.418 0.582
E14.4 With neurological complications
0.000 0.418 0.582
E14.2 Withrenal complications
0.000 0.418 0.582
E14.1 With ketoacidosis
0.000 0.418 0.582
E14.0 With coma
0.000 0.418 0.582
L28.2 Other prurigo
0.000 0.421 0.579
L28.1 Prurigo nodularis
0.000 0.421 0.579
H55 Nystagmus and other irregular eye movements
0.000 0.421 0.579
H16 Keratitis
0.000 0.423 0.577
E11.6 With other specified complications
0.000 0.425 0.575
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.425 0.575
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.426 0.573
E11.5 With peripheral circulatory complications
0.000 0.427 0.573
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.427 0.573
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.427 0.573
H05.2 Exophthalmic conditions
0.000 0.427 0.573
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.429 0.571
M10 Gout
0.000 0.430 0.570
H35 Other retinal disorders
0.000 0.432 0.568
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.432 0.568
M61 Calcification and ossification of muscle
0.000 0.432 0.568
M60 Myositis
0.000 0.432 0.568
E65-E68 Obesity and other hyperalimentation
0.000 0.433 0.567
B25-B34 Other viral diseases
0.000 0.434 0.566
H57 Other disorders of eye and adnexa
0.000 0.434 0.566
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.434 0.566
E16 Other disorders of pancreatic internal secretion
0.000 0.435 0.565

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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