TreeWAS – Variant ID: rs6923108

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.566	0.434
E10.9 Without complications	0.000	0.570	0.430
E10.4 With neurological complications	0.000	0.595	0.405
E10.5 With peripheral circulatory complications	0.000	0.601	0.399
E10.6 With other specified complications	0.000	0.608	0.392
E10.8 With unspecified complications	0.000	0.634	0.366
E10-E14 Diabetes mellitus	0.000	0.665	0.335
E10.1 With ketoacidosis	0.000	0.675	0.325
E10.2 With renal complications	0.000	0.676	0.324
E10.7 With multiple complications	0.000	0.688	0.312
K90 Intestinal malabsorption	0.000	0.699	0.301
E10.0 With coma	0.000	0.706	0.294
E83 Disorders of mineral metabolism	0.000	0.711	0.289
E13 Other specified diabetes mellitus	0.000	0.716	0.284
E10.3 With ophthalmic complications	0.000	0.717	0.283
E14 Unspecified diabetes mellitus	0.000	0.742	0.258
E13.9 Without complications	0.000	0.751	0.249
E14.3 With ophthalmic complications	0.000	0.753	0.247
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.756	0.244
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.757	0.243
E12 Malnutrition-related diabetes mellitus	0.000	0.759	0.241
E70-E90 Metabolic disorders	0.000	0.760	0.240
K90.3 Pancreatic steatorrhoea	0.000	0.784	0.216
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.784	0.216
K90.1 Tropical sprue	0.000	0.784	0.216
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.790	0.210
K90.8 Other intestinal malabsorption	0.000	0.793	0.207
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.793	0.207
E83.8 Other disorders of mineral metabolism	0.000	0.793	0.207
E83.2 Disorders of zinc metabolism	0.000	0.793	0.207
E83.0 Disorders of copper metabolism	0.000	0.793	0.207
E13.8 With unspecified complications	0.000	0.796	0.203
E13.7 With multiple complications	0.000	0.796	0.203
E13.6 With other specified complications	0.000	0.796	0.203
E13.5 With peripheral circulatory complications	0.000	0.796	0.203
E13.4 With neurological complications	0.000	0.796	0.203
E13.2 With renal complications	0.000	0.796	0.203
E13.1 With ketoacidosis	0.000	0.796	0.203
E13.0 With coma	0.000	0.796	0.203
E40-E46 Malnutrition	0.000	0.798	0.202
E88 Other metabolic disorders	0.000	0.799	0.201
E13.3 With ophthalmic complications	0.000	0.801	0.199
E14.5 With peripheral circulatory complications	0.000	0.804	0.196
E85 Amyloidosis	0.000	0.806	0.194
E16 Other disorders of pancreatic internal secretion	0.000	0.813	0.187
E14.7 With multiple complications	0.000	0.815	0.185
E14.6 With other specified complications	0.000	0.815	0.185
E14.2 Withrenal complications	0.000	0.815	0.185
E14.0 With coma	0.000	0.815	0.185
E14.4 With neurological complications	0.000	0.821	0.178
E16.2 Hypoglycaemia, unspecified	0.000	0.824	0.176
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.824	0.176
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.825	0.175
E12.9 Without complications	0.000	0.827	0.173
E12.8 With unspecified complications	0.000	0.827	0.173
E12.7 With multiple complications	0.000	0.827	0.173
E12.6 With other specified complications	0.000	0.827	0.173
E12.5 With peripheral circulatory complications	0.000	0.827	0.173
E12.4 With neurological complications	0.000	0.827	0.173
E12.3 With ophthalmic complications	0.000	0.827	0.173
E12.2 With renal complications	0.000	0.827	0.173
E12.1 With ketoacidosis	0.000	0.827	0.173
E12.0 With coma	0.000	0.827	0.173
E84 Cystic fibrosis	0.000	0.828	0.172
E77 Disorders of glycoprotein metabolism	0.000	0.828	0.172
E76 Disorders of glycosaminoglycan metabolism	0.000	0.828	0.172
E72 Other disorders of amino-acid metabolism	0.000	0.828	0.172
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.828	0.172
E70 Disorders of aromatic amino-acid metabolism	0.000	0.828	0.172
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.828	0.172
E46 Unspecified protein-energy malnutrition	0.000	0.828	0.172
E11 Non-insulin-dependent diabetes mellitus	0.000	0.828	0.172
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.830	0.170
E65-E68 Obesity and other hyperalimentation	0.000	0.836	0.164
E85.9 Amyloidosis, unspecified	0.000	0.838	0.162
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.839	0.161
E14.1 With ketoacidosis	0.000	0.843	0.157
E79 Disorders of purine and pyrimidine metabolism	0.000	0.844	0.156
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.847	0.153
E14.8 With unspecified complications	0.000	0.847	0.153
E88.8 Other specified metabolic disorders	0.000	0.847	0.152
E88.2 Lipomatosis, not elsewhere classified	0.000	0.849	0.151
E15 Nondiabetic hypoglycaemic coma	0.000	0.849	0.151
E85.4 Organ-limited amyloidosis	0.000	0.853	0.146
E11.5 With peripheral circulatory complications	0.000	0.855	0.145
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.855	0.145
E45 Retarded development following protein-energy malnutrition	0.000	0.855	0.145
E43 Unspecified severe protein-energy malnutrition	0.000	0.855	0.145
E42 Marasmic kwashiorkor	0.000	0.855	0.145
E41 Nutritional marasmus	0.000	0.855	0.145
E40 Kwashiorkor	0.000	0.855	0.145
E88.3 Tumour lysis syndrome	0.000	0.855	0.145
E89.2 Postprocedural hypoparathyroidism	0.000	0.859	0.141
E65 Localised adiposity	0.000	0.860	0.140
E85.8 Other amyloidosis	0.000	0.861	0.139
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.861	0.139
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.861	0.139
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.861	0.139
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.861	0.138
E74 Other disorders of carbohydrate metabolism	0.000	0.864	0.136
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.864	0.136
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.866	0.134
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.866	0.134
E16.4 Abnormal secretion of gastrin	0.000	0.866	0.134
E16.3 Increased secretion of glucagon	0.000	0.866	0.134
E88.9 Metabolic disorder, unspecified	0.000	0.866	0.134
E11.0 With coma	0.000	0.868	0.132
E89.4 Postprocedural ovarian failure	0.000	0.869	0.131
E75.5 Other lipid storage disorders	0.000	0.870	0.130
E85.3 Secondary systemic amyloidosis	0.000	0.870	0.130
E80.4 Gilbert's syndrome	0.000	0.870	0.130
E83.4 Disorders of magnesium metabolism	0.000	0.871	0.129
E89.0 Postprocedural hypothyroidism	0.000	0.871	0.129
E11.8 With unspecified complications	0.000	0.871	0.129
E11.1 With ketoacidosis	0.000	0.874	0.126
E75.6 Lipid storage disorder, unspecified	0.000	0.874	0.126
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.874	0.126
E75.3 Sphingolipidosis, unspecified	0.000	0.874	0.126
E75.2 Other sphingolipidosis	0.000	0.874	0.126
E75.1 Other gangliosidosis	0.000	0.874	0.126
E75.0 GM2 gangliosidosis	0.000	0.874	0.126
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.874	0.126
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.874	0.126
E89.5 Postprocedural testicular hypofunction	0.000	0.874	0.126
E89.1 Postprocedural hypoinsulinaemia	0.000	0.874	0.126
E73 Lactose intolerance	0.000	0.874	0.125
E11.2 With renal complications	0.000	0.875	0.125
E83.3 Disorders of phosphorus metabolism	0.000	0.876	0.124
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.876	0.124
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.876	0.124
E70.3 Albinism	0.000	0.876	0.124
E70.2 Disorders of tyrosine metabolism	0.000	0.876	0.124
E70.1 Other hyperphenylalaninaemias	0.000	0.876	0.124
E70.0 Classical phenylketonuria	0.000	0.876	0.124
E71.3 Disorders of fatty-acid metabolism	0.000	0.876	0.124
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.876	0.124
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.876	0.124
E71.0 Maple-syrup-urine disease	0.000	0.876	0.124
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.876	0.124
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.876	0.124
E72.5 Disorders of glycine metabolism	0.000	0.876	0.124
E72.4 Disorders of ornithine metabolism	0.000	0.876	0.124
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.876	0.124
E72.2 Disorders of urea cycle metabolism	0.000	0.876	0.124
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.876	0.124
E72.0 Disorders of amino-acid transport	0.000	0.876	0.124
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.876	0.124
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.876	0.124
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.876	0.124
E76.2 Other mucopolysaccharidoses	0.000	0.876	0.124
E76.1 Mucopolysaccharidosis, type II	0.000	0.876	0.124
E76.0 Mucopolysaccharidosis, type I	0.000	0.876	0.124
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.876	0.124
E77.8 Other disorders of glycoprotein metabolism	0.000	0.876	0.124
E77.1 Defects in glycoprotein degradation	0.000	0.876	0.124
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.876	0.124
E84.9 Cystic fibrosis, unspecified	0.000	0.876	0.124
E84.8 Cystic fibrosis with other manifestations	0.000	0.876	0.124
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.876	0.124
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.876	0.124
E11.7 With multiple complications	0.000	0.876	0.123
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.878	0.122
E80.5 Crigler-Najjar syndrome	0.000	0.878	0.122
E80.3 Defects of catalase and peroxydase	0.000	0.878	0.122
E80.1 Porphyria cutanea tarda	0.000	0.878	0.122
E80.0 Hereditary erythropoietic porphyria	0.000	0.878	0.122
E11.6 With other specified complications	0.000	0.879	0.121
E00-E07 Disorders of thyroid gland	0.000	0.881	0.119
E67 Other hyperalimentation	0.000	0.882	0.118
E68 Sequelae of hyperalimentation	0.000	0.882	0.118
E11.4 With neurological complications	0.000	0.882	0.118
E80.2 Other porphyria	0.000	0.882	0.117
E80.6 Other disorders of bilirubin metabolism	0.000	0.884	0.116
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.888	0.112
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.888	0.112
E79.1 Lesch-Nyhan syndrome	0.000	0.888	0.112
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.895	0.105
E44.1 Mild protein-energy malnutrition	0.000	0.896	0.104
E44.0 Moderate protein-energy malnutrition	0.000	0.896	0.104
E16.1 Other hypoglycaemia	0.000	0.898	0.102
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.899	0.101
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.902	0.098
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.902	0.098
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.902	0.098
E74.2 Disorders of galactose metabolism	0.000	0.902	0.098
E74.1 Disorders of fructose metabolism	0.000	0.902	0.098
E11.3 With ophthalmic complications	0.000	0.904	0.096
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.904	0.096
K90.9 Intestinal malabsorption, unspecified	0.001	0.907	0.093
E04 Other non-toxic goitre	0.000	0.907	0.093
E07 Other disorders of thyroid	0.000	0.907	0.093
E73.8 Other lactose intolerance	0.000	0.910	0.090
E73.1 Secondary lactase deficiency	0.000	0.910	0.090
E73.0 Congenital lactase deficiency	0.000	0.910	0.090
E74.0 Glycogen storage disease	0.000	0.910	0.089
E50-E64 Other nutritional deficiencies	0.000	0.913	0.087
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.915	0.085
E00 Congenital iodine-deficiency syndrome	0.000	0.915	0.085
E78.4 Other hyperlipidaemia	0.000	0.915	0.085
E67.8 Other specified hyperalimentation	0.000	0.915	0.085
E67.3 Hypervitaminosis D	0.000	0.915	0.085
E67.2 Megavitamin-B6 syndrome	0.000	0.915	0.085
E67.1 Hypercarotenaemia	0.000	0.915	0.085
E67.0 Hypervitaminosis A	0.000	0.915	0.085
E04.9 Non-toxic goitre, unspecified	0.000	0.918	0.082
E06 Thyroiditis	0.000	0.919	0.081
E78.6 Lipoprotein deficiency	0.000	0.921	0.079
E07.9 Disorder of thyroid, unspecified	0.000	0.922	0.078
E03 Other hypothyroidism	0.000	0.922	0.078
E89.3 Postprocedural hypopituitarism	0.000	0.924	0.076
E78.3 Hyperchylomicronaemia	0.000	0.925	0.075
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.925	0.074
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.926	0.074
E78.1 Pure hyperglyceridaemia	0.000	0.929	0.071
E83.5 Disorders of calcium metabolism	0.000	0.929	0.071
E04.0 Non-toxic diffuse goitre	0.000	0.930	0.070
E03.8 Other specified hypothyroidism	0.000	0.930	0.070
E78.2 Mixed hyperlipidaemia	0.000	0.931	0.069
E87.3 Alkalosis	0.000	0.933	0.067
E14.9 Without complications	0.000	0.933	0.067
E04.8 Other specified non-toxic goitre	0.000	0.933	0.067
E07.1 Dyshormogenetic goitre	0.000	0.933	0.066
E07.0 Hypersecretion of calcitonin	0.000	0.933	0.066
E20-E35 Disorders of other endocrine glands	0.000	0.934	0.066
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.935	0.065
E04.2 Non-toxic multinodular goitre	0.000	0.936	0.064
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.937	0.062
E63 Other nutritional deficiencies	0.000	0.937	0.062
E56 Other vitamin deficiencies	0.000	0.937	0.062
E50 Vitamin A deficiency	0.000	0.937	0.062
E60 Dietary zinc deficiency	0.000	0.937	0.062
E59 Dietary selenium deficiency	0.000	0.937	0.062
E54 Ascorbic acid deficiency	0.000	0.937	0.062
E52 Niacin deficiency [pellagra]	0.000	0.937	0.062
E58 Dietary calcium deficiency	0.000	0.938	0.062
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.939	0.061
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.939	0.061
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.939	0.061
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.939	0.061
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.939	0.061
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.939	0.061
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.939	0.061
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.939	0.061
E87.0 Hyperosmolality and hypernatraemia	0.000	0.940	0.060
E53 Deficiency of other B group vitamins	0.000	0.940	0.060
E06.3 Autoimmune thyroiditis	0.000	0.940	0.060
E07.8 Other specified disorders of thyroid	0.000	0.941	0.059
E06.5 Other chronic thyroiditis	0.000	0.942	0.058
E06.4 Drug-induced thyroiditis	0.000	0.942	0.058
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.942	0.058
E06.1 Subacute thyroiditis	0.000	0.942	0.058
E06.0 Acute thyroiditis	0.000	0.942	0.058
E51 Thiamine deficiency	0.000	0.942	0.057
E03.5 Myxoedema coma	0.000	0.944	0.056
E03.4 Atrophy of thyroid (acquired)	0.000	0.944	0.056
E03.3 Postinfectious hypothyroidism	0.000	0.944	0.056
E03.1 Congenital hypothyroidism without goitre	0.000	0.944	0.056
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.944	0.056
E66 Obesity	0.000	0.945	0.055
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.945	0.055
E87.7 Fluid overload	0.000	0.947	0.053
E87.4 Mixed disorder of acid-base balance	0.000	0.947	0.053
E87.2 Acidosis	0.000	0.947	0.053
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.947	0.053
E06.9 Thyroiditis, unspecified	0.000	0.949	0.051
E28 Ovarian dysfunction	0.000	0.949	0.050
E20 Hypoparathyroidism	0.000	0.950	0.050
E26 Hyperaldosteronism	0.000	0.951	0.049
E55 Vitamin D deficiency	0.000	0.951	0.049
E04.1 Non-toxic single thyroid nodule	0.000	0.952	0.048
E29 Testicular dysfunction	0.000	0.952	0.047
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.953	0.047
E32 Diseases of thymus	0.000	0.953	0.047
E31 Polyglandular dysfunction	0.000	0.953	0.047
E30 Disorders of puberty, not elsewhere classified	0.000	0.953	0.047
E25 Adrenogenital disorders	0.000	0.953	0.047
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.954	0.046
E23 Hypofunction and other disorders of pituitary gland	0.000	0.954	0.046
E28.2 Polycystic ovarian syndrome	0.000	0.955	0.045
E50.9 Vitamin A deficiency, unspecified	0.000	0.955	0.045
E50.8 Other manifestations of vitamin A deficiency	0.000	0.955	0.045
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.955	0.045
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.955	0.045
E50.5 Vitamin A deficiency with night blindness	0.000	0.955	0.045
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.955	0.045
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.955	0.045
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.955	0.045
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.955	0.045
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.955	0.045
E56.9 Vitamin deficiency, unspecified	0.000	0.955	0.045
E56.8 Deficiency of other vitamins	0.000	0.955	0.045
E56.1 Deficiency of vitamin K	0.000	0.955	0.045
E56.0 Deficiency of vitamin E	0.000	0.955	0.045
E63.9 Nutritional deficiency, unspecified	0.000	0.955	0.045
E63.8 Other specified nutritional deficiencies	0.000	0.955	0.045
E63.1 Imbalance of constituents of food intake	0.000	0.955	0.045
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.955	0.045
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.955	0.045
E64.8 Sequelae of other nutritional deficiencies	0.000	0.955	0.045
E64.3 Sequelae of rickets	0.000	0.955	0.045
E64.2 Sequelae of vitamin C deficiency	0.000	0.955	0.045
E64.1 Sequelae of vitamin A deficiency	0.000	0.955	0.045
E64.0 Sequelae of protein-energy malnutrition	0.000	0.955	0.045
E78.8 Other disorders of lipoprotein metabolism	0.000	0.955	0.045
E73.9 Lactose intolerance, unspecified	0.001	0.956	0.043
E53.1 Pyridoxine deficiency	0.000	0.957	0.043
E53.0 Riboflavin deficiency	0.000	0.957	0.043
E34 Other endocrine disorders	0.000	0.957	0.043
E53.9 Vitamin B deficiency, unspecified	0.000	0.957	0.043
E24 Cushing's syndrome	0.000	0.957	0.043
E87.5 Hyperkalaemia	0.000	0.957	0.043
E23.2 Diabetes insipidus	0.000	0.958	0.042
E51.9 Thiamine deficiency, unspecified	0.000	0.958	0.041
E51.8 Other manifestations of thiamine deficiency	0.000	0.958	0.041
E51.1 Beriberi	0.000	0.958	0.041
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.959	0.041
E53.8 Deficiency of other specified B group vitamins	0.000	0.959	0.041
E27 Other disorders of adrenal gland	0.000	0.960	0.040
E66.1 Drug-induced obesity	0.000	0.960	0.039
E05.8 Other thyrotoxicosis	0.000	0.961	0.039
E20.9 Hypoparathyroidism, unspecified	0.000	0.961	0.039
E05.5 Thyroid crisis or storm	0.000	0.962	0.038
E05.4 Thyrotoxicosis factitia	0.000	0.962	0.038
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.962	0.038
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.962	0.038
E66.0 Obesity due to excess calories	0.000	0.962	0.038
E26.0 Primary hyperaldosteronism	0.000	0.962	0.038
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.962	0.038
E27.1 Primary adrenocortical insufficiency	0.000	0.963	0.037
E51.2 Wernicke's encephalopathy	0.000	0.963	0.036
E28.9 Ovarian dysfunction, unspecified	0.000	0.963	0.036
E28.8 Other ovarian dysfunction	0.000	0.963	0.036
E28.1 Androgen excess	0.000	0.963	0.036
E28.0 Oestrogen excess	0.000	0.963	0.036
E20.8 Other hypoparathyroidism	0.000	0.964	0.036
E20.1 Pseudohypoparathyroidism	0.000	0.964	0.036
E20.0 Idiopathic hypoparathyroidism	0.000	0.964	0.036
E24.2 Drug-induced Cushing's syndrome	0.000	0.964	0.036
E26.9 Hyperaldosteronism, unspecified	0.000	0.964	0.036
E26.8 Other hyperaldosteronism	0.000	0.964	0.036
E26.1 Secondary hyperaldosteronism	0.000	0.964	0.036
E55.0 Rickets, active	0.000	0.964	0.035
E29.1 Testicular hypofunction	0.000	0.966	0.034
E29.9 Testicular dysfunction, unspecified	0.000	0.966	0.034
E29.8 Other testicular dysfunction	0.000	0.966	0.034
E29.0 Testicular hyperfunction	0.000	0.966	0.034
E25.9 Adrenogenital disorder, unspecified	0.000	0.966	0.034
E25.8 Other adrenogenital disorders	0.000	0.966	0.034
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.966	0.034
E30.9 Disorder of puberty, unspecified	0.000	0.966	0.034
E30.8 Other disorders of puberty	0.000	0.966	0.034
E30.1 Precocious puberty	0.000	0.966	0.034
E30.0 Delayed puberty	0.000	0.966	0.034
E31.9 Polyglandular dysfunction, unspecified	0.000	0.966	0.034
E31.8 Other polyglandular dysfunction	0.000	0.966	0.034
E31.1 Polyglandular hyperfunction	0.000	0.966	0.034
E31.0 Autoimmune polyglandular failure	0.000	0.966	0.034
E32.9 Disease of thymus, unspecified	0.000	0.966	0.034
E32.8 Other diseases of thymus	0.000	0.966	0.034
E32.1 Abscess of thymus	0.000	0.966	0.034
E32.0 Persistent hyperplasia of thymus	0.000	0.966	0.034
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.966	0.034
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.966	0.034
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.966	0.034
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.967	0.033
E23.1 Drug-induced hypopituitarism	0.000	0.967	0.033
E61 Deficiency of other nutrient elements	0.001	0.967	0.032
E23.7 Disorder of pituitary gland, unspecified	0.000	0.968	0.032
E34.5 Androgen resistance syndrome	0.000	0.969	0.031
E34.4 Constitutional tall stature	0.000	0.969	0.031
E34.3 Short stature, not elsewhere classified	0.000	0.969	0.031
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.969	0.031
E34.1 Other hypersecretion of intestinal hormones	0.000	0.969	0.031
E24.8 Other Cushing's syndrome	0.000	0.969	0.031
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.969	0.031
E24.3 Ectopic ACTH syndrome	0.000	0.969	0.031
E24.1 Nelson's syndrome	0.000	0.969	0.031
E34.9 Endocrine disorder, unspecified	0.000	0.969	0.031
E34.8 Other specified endocrine disorders	0.000	0.970	0.030
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.970	0.029
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.971	0.029
E23.6 Other disorders of pituitary gland	0.000	0.971	0.029
E27.5 Adrenomedullary hyperfunction	0.000	0.971	0.028
E27.0 Other adrenocortical overactivity	0.000	0.971	0.028
E34.0 Carcinoid syndrome	0.000	0.972	0.028
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.972	0.028
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.972	0.028
E24.0 Pituitary-dependent Cushing's disease	0.000	0.972	0.028
E86 Volume depletion	0.000	0.973	0.027
E61.9 Deficiency of nutrient element, unspecified	0.001	0.976	0.023
E61.8 Deficiency of other specified nutrient elements	0.001	0.976	0.023
E61.7 Deficiency of multiple nutrient elements	0.001	0.976	0.023
E61.6 Vanadium deficiency	0.001	0.976	0.023
E61.5 Molybdenum deficiency	0.001	0.976	0.023
E61.4 Chromium deficiency	0.001	0.976	0.023
E61.3 Manganese deficiency	0.001	0.976	0.023
E61.0 Copper deficiency	0.001	0.976	0.023
E28.3 Primary ovarian failure	0.000	0.977	0.023
E55.9 Vitamin D deficiency, unspecified	0.000	0.977	0.022
E27.2 Addisonian crisis	0.000	0.978	0.022
E24.9 Cushing's syndrome, unspecified	0.000	0.978	0.022
E21.3 Hyperparathyroidism, unspecified	0.000	0.978	0.022
E21.4 Other specified disorders of parathyroid gland	0.000	0.979	0.021
E21.2 Other hyperparathyroidism	0.000	0.979	0.021
E22 Hyperfunction of pituitary gland	0.000	0.979	0.020
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.980	0.020
K90-K93 Other diseases of the digestive system	0.000	0.981	0.019
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.981	0.019
E61.2 Magnesium deficiency	0.001	0.981	0.018
E27.8 Other specified disorders of adrenal gland	0.000	0.981	0.018
E27.9 Disorder of adrenal gland, unspecified	0.000	0.983	0.016
E23.0 Hypopituitarism	0.000	0.984	0.016
E66.9 Obesity, unspecified	0.000	0.985	0.015
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.985	0.015
E22.8 Other hyperfunction of pituitary gland	0.000	0.985	0.015
C71.2 Temporal lobe	0.015	0.985	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.986	0.014
C71 Malignant neoplasm of brain	0.014	0.986	0.000
R31 Unspecified haematuria	0.014	0.986	0.000
C71.9 Brain, unspecified	0.014	0.986	0.000
E22.1 Hyperprolactinaemia	0.000	0.986	0.013
E05.9 Thyrotoxicosis, unspecified	0.000	0.988	0.012
C71.3 Parietal lobe	0.012	0.988	0.000
C71.1 Frontal lobe	0.012	0.988	0.000
E21.0 Primary hyperparathyroidism	0.000	0.989	0.011
C71.7 Brain stem	0.011	0.989	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.990	0.010
K93.1 Megacolon in Chagas' disease	0.000	0.990	0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.990	0.010
C71.6 Cerebellum	0.010	0.990	0.000
C71.5 Cerebral ventricle	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
C71.8 Overlapping lesion of brain	0.010	0.990	0.000
E22.0 Acromegaly and pituitary gigantism	0.001	0.990	0.009
E87.6 Hypokalaemia	0.000	0.991	0.009
G44.2 Tension-type headache	0.009	0.991	0.000
C71.4 Occipital lobe	0.009	0.991	0.000
E61.1 Iron deficiency	0.001	0.992	0.007
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.008	0.992	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.993	0.007
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.993	0.007
E66.8 Other obesity	0.000	0.993	0.007
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.007	0.993	0.000
C70 Malignant neoplasm of meninges	0.006	0.993	0.000
M41.9 Scoliosis, unspecified	0.006	0.994	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.006	0.994	0.000
C69.9 Eye, unspecified	0.006	0.994	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.994	0.006
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.006	0.994	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.006	0.994	0.000
G31.0 Circumscribed brain atrophy	0.000	0.994	0.006
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.006	0.994	0.000
N04.9 Unspecified	0.000	0.994	0.006
C69.3 Choroid	0.006	0.994	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.006	0.994	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.006	0.994	0.000
M79.10 Myalgia (Multiple sites)	0.006	0.994	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.994	0.006
M67.8 Other specified disorders of synovium and tendon	0.000	0.994	0.006
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.005	0.995	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.005	0.995	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.005	0.995	0.000
G44 Other headache syndromes	0.005	0.995	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.995	0.005
N50.1 Vascular disorders of male genital organs	0.000	0.995	0.005
C72.9 Central nervous system, unspecified	0.004	0.995	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.995	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.995	0.000
C72.4 Acoustic nerve	0.004	0.995	0.000
C72.3 Optic nerve	0.004	0.995	0.000
C72.2 Olfactory nerve	0.004	0.995	0.000
C72.1 Cauda equina	0.004	0.995	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.004	0.995	0.000
G44.8 Other specified headache syndromes	0.004	0.996	0.000
C72.0 Spinal cord	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.004	0.996	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.996	0.004
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.996	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.996	0.004
M79.19 Myalgia (Site unspecified)	0.004	0.996	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.996	0.004
G44.1 Vascular headache, not elsewhere classified	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
G44.0 Cluster headache syndrome	0.004	0.996	0.000
G44.3 Chronic posttraumatic headache	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations