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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6935723
log Bayes Factor = 113.539
Chromosome 6   position 32,681,669  (GRCh37) Explore rs6935723 on Ensembl!
Variant rs6935723 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.002 0.998
M05 Seropositive rheumatoid arthritis
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.998 0.002 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.003 0.997
M05-M14 Inflammatory polyarthropathies
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
Chapter X Diseases of the respiratory system
0.000 0.004 0.996
K90.0 Coeliac disease
0.000 0.005 0.995
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.016 0.984
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.017 0.983
E05.9 Thyrotoxicosis, unspecified
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.023 0.977
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.025 0.975
E10.2 With renal complications
0.000 0.026 0.974
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.026 0.974
J20-J22 Other acute lower respiratory infections
0.000 0.031 0.969
L40.0 Psoriasis vulgaris
0.967 0.033 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.040 0.960
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.041 0.959
E16 Other disorders of pancreatic internal secretion
0.000 0.043 0.957
J80 Adult respiratory distress syndrome
0.000 0.050 0.950
M06.3 Rheumatoid nodule
0.000 0.051 0.949
E04 Other non-toxic goitre
0.000 0.053 0.947
E16.2 Hypoglycaemia, unspecified
0.000 0.053 0.947
M06.0 Seronegative rheumatoid arthritis
0.000 0.054 0.946
J22 Unspecified acute lower respiratory infection
0.000 0.055 0.945
J81 Pulmonary oedema
0.000 0.057 0.943
E14 Unspecified diabetes mellitus
0.000 0.058 0.942
J84 Other interstitial pulmonary diseases
0.000 0.065 0.935
E06 Thyroiditis
0.000 0.073 0.927
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.075 0.925
M35.1 Other overlap syndromes
0.000 0.079 0.921
E14.3 With ophthalmic complications
0.000 0.081 0.919
M06.34 Rheumatoid nodule (Hand)
0.000 0.091 0.909
E10.0 With coma
0.000 0.137 0.863
L40.4 Guttate psoriasis
0.860 0.140 0.000
E06.3 Autoimmune thyroiditis
0.000 0.142 0.858
E04.2 Non-toxic multinodular goitre
0.000 0.147 0.853
E04.0 Non-toxic diffuse goitre
0.000 0.147 0.853
E10.8 With unspecified complications
0.000 0.149 0.851
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.150 0.850
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.156 0.844
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.170 0.830
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.176 0.824
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.179 0.821
L40.1 Generalised pustular psoriasis
0.813 0.187 0.000
J95-J99 Other diseases of the respiratory system
0.000 0.188 0.812
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.189 0.811
E50-E64 Other nutritional deficiencies
0.000 0.189 0.811
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.191 0.809
E04.9 Non-toxic goitre, unspecified
0.000 0.205 0.795
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.206 0.794
L40.8 Other psoriasis
0.790 0.210 0.000
M35.2 Behcet's disease
0.000 0.215 0.785
J42 Unspecified chronic bronchitis
0.000 0.222 0.778
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.224 0.776
M06.4 Inflammatory polyarthropathy
0.000 0.227 0.773
J21 Acute bronchiolitis
0.000 0.234 0.766
L40.3 Pustulosis palmaris et plantaris
0.765 0.235 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.236 0.764
E10.6 With other specified complications
0.000 0.237 0.763
E07 Other disorders of thyroid
0.000 0.238 0.762
J46 Status asthmaticus
0.000 0.248 0.752
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.250 0.750
J84.8 Other specified interstitial pulmonary diseases
0.000 0.251 0.749
E20-E35 Disorders of other endocrine glands
0.000 0.251 0.749
J41 Simple and mucopurulent chronic bronchitis
0.000 0.255 0.745
E06.9 Thyroiditis, unspecified
0.000 0.269 0.731
E05.8 Other thyrotoxicosis
0.000 0.273 0.727
E27 Other disorders of adrenal gland
0.000 0.275 0.725
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.276 0.724
M12 Other specific arthropathies
0.000 0.276 0.724
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.285 0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.285 0.715
M05.2 Rheumatoid vasculitis
0.000 0.285 0.715
M05.1 Rheumatoid lung disease
0.000 0.285 0.715
M05.0 Felty's syndrome
0.000 0.285 0.715
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.286 0.714
M08 Juvenile arthritis
0.000 0.286 0.714
E27.1 Primary adrenocortical insufficiency
0.000 0.287 0.713
J00-J06 Acute upper respiratory infections
0.000 0.295 0.705
E15 Nondiabetic hypoglycaemic coma
0.000 0.301 0.699
M35.8 Other specified systemic involvement of connective tissue
0.000 0.304 0.696
E14.1 With ketoacidosis
0.000 0.308 0.692
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.314 0.686
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.314 0.686
E16.4 Abnormal secretion of gastrin
0.000 0.314 0.686
E16.3 Increased secretion of glucagon
0.000 0.314 0.686
E14.5 With peripheral circulatory complications
0.000 0.316 0.684
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.319 0.680
M06.38 Rheumatoid nodule (Other)
0.000 0.319 0.680
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.319 0.680
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.319 0.680
M06.33 Rheumatoid nodule (Forearm)
0.000 0.319 0.680
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.319 0.680
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.319 0.680
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.320 0.679
E04.8 Other specified non-toxic goitre
0.000 0.321 0.679
J20 Acute bronchitis
0.000 0.322 0.678
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.322 0.678
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.322 0.678
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.322 0.678
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.322 0.678
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.322 0.678
E14.7 With multiple complications
0.000 0.324 0.675
E14.6 With other specified complications
0.000 0.324 0.675
E14.0 With coma
0.000 0.324 0.675
E55 Vitamin D deficiency
0.000 0.328 0.671
J84.0 Alveolar and parietoalveolar conditions
0.000 0.330 0.670
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.332 0.668
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.334 0.666
E06.5 Other chronic thyroiditis
0.000 0.335 0.665
E06.4 Drug-induced thyroiditis
0.000 0.335 0.665
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.335 0.665
E06.1 Subacute thyroiditis
0.000 0.335 0.665
E06.0 Acute thyroiditis
0.000 0.335 0.665
E14.8 With unspecified complications
0.000 0.345 0.655
E14.2 Withrenal complications
0.000 0.345 0.655
M10 Gout
0.000 0.346 0.654
E61 Deficiency of other nutrient elements
0.000 0.348 0.652
J33 Nasal polyp
0.000 0.349 0.651
J30-J39 Other diseases of upper respiratory tract
0.000 0.353 0.647
E40-E46 Malnutrition
0.000 0.357 0.643
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.357 0.643
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.362 0.638
M35.7 Hypermobility syndrome
0.000 0.367 0.632
E27.8 Other specified disorders of adrenal gland
0.000 0.368 0.632
J33.9 Nasal polyp, unspecified
0.000 0.368 0.632
M14 Arthropathies in other diseases classified elsewhere
0.000 0.370 0.630
J21.9 Acute bronchiolitis, unspecified
0.000 0.379 0.621
E14.4 With neurological complications
0.000 0.383 0.616
E28 Ovarian dysfunction
0.000 0.392 0.608
E07.8 Other specified disorders of thyroid
0.000 0.400 0.600
J00 Acute nasopharyngitis [common cold]
0.000 0.401 0.599
J33.8 Other polyp of sinus
0.000 0.403 0.597
J99.0 Rheumatoid lung disease
0.000 0.403 0.597
J33.0 Polyp of nasal cavity
0.000 0.406 0.594
H36 Retinal disorders in diseases classified elsewhere
0.000 0.411 0.589
E53 Deficiency of other B group vitamins
0.000 0.416 0.584
J96 Respiratory failure, not elsewhere classified
0.000 0.418 0.582
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.419 0.581
E63 Other nutritional deficiencies
0.000 0.419 0.581
E51 Thiamine deficiency
0.000 0.419 0.581
E50 Vitamin A deficiency
0.000 0.419 0.581
E60 Dietary zinc deficiency
0.000 0.419 0.581
E59 Dietary selenium deficiency
0.000 0.419 0.581
E54 Ascorbic acid deficiency
0.000 0.419 0.581
E52 Niacin deficiency [pellagra]
0.000 0.419 0.581
J09-J18 Influenza and pneumonia
0.000 0.419 0.581
J60-J70 Lung diseases due to external agents
0.000 0.419 0.581
E29 Testicular dysfunction
0.000 0.420 0.580
J43 Emphysema
0.000 0.422 0.578
J98 Other respiratory disorders
0.000 0.424 0.576
E55.9 Vitamin D deficiency, unspecified
0.000 0.428 0.572
E14.9 Without complications
0.000 0.428 0.572
E26 Hyperaldosteronism
0.000 0.429 0.571
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.429 0.570
M10.0 Idiopathic gout
0.000 0.435 0.565
E56 Other vitamin deficiencies
0.000 0.436 0.564
J41.0 Simple chronic bronchitis
0.000 0.438 0.562
E23 Hypofunction and other disorders of pituitary gland
0.000 0.442 0.558
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.446 0.554
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.446 0.554
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.446 0.554
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.446 0.554
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.446 0.554
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.446 0.554
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.446 0.554
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.446 0.554
M12.3 Palindromic rheumatism
0.000 0.446 0.554
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.449 0.551
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.450 0.549
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.450 0.549
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.450 0.549
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.451 0.549
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.452 0.548
E07.1 Dyshormogenetic goitre
0.000 0.454 0.546
E07.0 Hypersecretion of calcitonin
0.000 0.454 0.546
J01 Acute sinusitis
0.000 0.454 0.546
M11 Other crystal arthropathies
0.000 0.456 0.544
E34 Other endocrine disorders
0.000 0.456 0.544
J10 Influenza due to identified influenza virus
0.000 0.461 0.539
E61.1 Iron deficiency
0.000 0.462 0.538
J98.9 Respiratory disorder, unspecified
0.000 0.462 0.538
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.463 0.537
E32 Diseases of thymus
0.000 0.463 0.537
E31 Polyglandular dysfunction
0.000 0.463 0.537
E30 Disorders of puberty, not elsewhere classified
0.000 0.463 0.537
E07.9 Disorder of thyroid, unspecified
0.000 0.465 0.535
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.466 0.534
J41.1 Mucopurulent chronic bronchitis
0.000 0.466 0.534
E16.1 Other hypoglycaemia
0.000 0.467 0.532
J40 Bronchitis, not specified as acute or chronic
0.000 0.469 0.531
E27.5 Adrenomedullary hyperfunction
0.000 0.480 0.520
E27.0 Other adrenocortical overactivity
0.000 0.480 0.520
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.481 0.519
M12.5 Traumatic arthropathy
0.000 0.481 0.519
M12.4 Intermittent hydrarthrosis
0.000 0.481 0.519
M12.1 Kaschin-Beck disease
0.000 0.481 0.519
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.481 0.519
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.487 0.513
M05.08 Felty's syndrome (Other)
0.000 0.487 0.513
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.487 0.513
M05.06 Felty's syndrome (Lower leg)
0.000 0.487 0.513
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.487 0.513
M05.04 Felty's syndrome (Hand)
0.000 0.487 0.513
M05.03 Felty's syndrome (Forearm)
0.000 0.487 0.513
M05.02 Felty's syndrome (Upper arm)
0.000 0.487 0.513
M05.01 Felty's syndrome (Shoulder region)
0.000 0.487 0.513
M05.00 Felty's syndrome (Multiple sites)
0.000 0.487 0.513
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.487 0.513
M05.18 Rheumatoid lung disease (Other)
0.000 0.487 0.513
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.487 0.513
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.487 0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.487 0.513
M05.14 Rheumatoid lung disease (Hand)
0.000 0.487 0.513
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.487 0.513
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.487 0.513
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.487 0.513
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.487 0.513
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.487 0.513
M05.28 Rheumatoid vasculitis (Other)
0.000 0.487 0.513
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.487 0.513
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.487 0.513
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.487 0.513
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.487 0.513
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.487 0.513
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.487 0.513
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.487 0.513
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.487 0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.487 0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.487 0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.487 0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.487 0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.487 0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.487 0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.487 0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.487 0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.487 0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.487 0.513
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.487 0.513
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.487 0.513
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
J32 Chronic sinusitis
0.000 0.488 0.512
M08.9 Juvenile arthritis, unspecified
0.000 0.488 0.512
M08.8 Other juvenile arthritis
0.000 0.488 0.512
M08.4 Pauciarticular juvenile arthritis
0.000 0.488 0.512
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.488 0.512
M08.2 Juvenile arthritis with systemic onset
0.000 0.488 0.512
M08.1 Juvenile ankylosing spondylitis
0.000 0.488 0.512
M08.0 Juvenile rheumatoid arthritis
0.000 0.488 0.512
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.488 0.512
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.488 0.512
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.488 0.512
M09.0 Juvenile arthritis in psoriasis
0.000 0.488 0.512
E58 Dietary calcium deficiency
0.000 0.493 0.507
J04 Acute laryngitis and tracheitis
0.000 0.498 0.502
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.498 0.501
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.499 0.501
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.499 0.501
J20.9 Acute bronchitis, unspecified
0.000 0.500 0.500
E20 Hypoparathyroidism
0.000 0.501 0.498
E28.2 Polycystic ovarian syndrome
0.000 0.503 0.497
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.507 0.493
M12.2 Villonodular synovitis (pigmented)
0.000 0.511 0.489
J20.7 Acute bronchitis due to echovirus
0.000 0.513 0.486
J20.6 Acute bronchitis due to rhinovirus
0.000 0.513 0.486
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.513 0.486
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.513 0.486
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.513 0.486
J20.2 Acute bronchitis due to streptococcus
0.000 0.513 0.486
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.513 0.486
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.513 0.486
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.516 0.484
J33.1 Polypoid sinus degeneration
0.000 0.516 0.483
E55.0 Rickets, active
0.000 0.518 0.481
J98.4 Other disorders of lung
0.000 0.522 0.478
J98.1 Pulmonary collapse
0.000 0.524 0.476
J32.9 Chronic sinusitis, unspecified
0.000 0.524 0.476
N48 Other disorders of penis
0.474 0.526 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.530 0.470
M10.4 Other secondary gout
0.000 0.531 0.469
M10.3 Gout due to impairment of renal function
0.000 0.531 0.469
M10.2 Drug-induced gout
0.000 0.531 0.469
M10.1 Lead-induced gout
0.000 0.531 0.469
E61.9 Deficiency of nutrient element, unspecified
0.000 0.532 0.467
E61.8 Deficiency of other specified nutrient elements
0.000 0.532 0.467
E61.7 Deficiency of multiple nutrient elements
0.000 0.532 0.467
E61.6 Vanadium deficiency
0.000 0.532 0.467
E61.5 Molybdenum deficiency
0.000 0.532 0.467
E61.4 Chromium deficiency
0.000 0.532 0.467
E61.3 Manganese deficiency
0.000 0.532 0.467
E61.2 Magnesium deficiency
0.000 0.532 0.467
E61.0 Copper deficiency
0.000 0.532 0.467
J64 Unspecified pneumoconiosis
0.000 0.533 0.467
M20-M25 Other joint disorders
0.000 0.536 0.464
N48.1 Balanoposthitis
0.462 0.538 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.539 0.461
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.539 0.461
E45 Retarded development following protein-energy malnutrition
0.000 0.539 0.461
E43 Unspecified severe protein-energy malnutrition
0.000 0.539 0.461
E42 Marasmic kwashiorkor
0.000 0.539 0.461
E41 Nutritional marasmus
0.000 0.539 0.461
E40 Kwashiorkor
0.000 0.539 0.461
L40-L45 Papulosquamous disorders
0.438 0.540 0.021
N48.8 Other specified disorders of penis
0.459 0.541 0.000
M34 Systemic sclerosis
0.000 0.541 0.459
J37 Chronic laryngitis and laryngotracheitis
0.000 0.541 0.459
E29.1 Testicular hypofunction
0.000 0.542 0.458
E11 Non-insulin-dependent diabetes mellitus
0.000 0.543 0.457
J43.2 Centrilobular emphysema
0.000 0.544 0.456
E53.9 Vitamin B deficiency, unspecified
0.000 0.544 0.455
E13 Other specified diabetes mellitus
0.001 0.545 0.454
J20.8 Acute bronchitis due to other specified organisms
0.000 0.546 0.454
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.547 0.453
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.548 0.451
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.548 0.451
M14.4 Arthropathy in amyloidosis
0.000 0.548 0.451
M14.3 Lipoid dermatoarthritis
0.000 0.548 0.451
M14.2 Diabetic arthropathy
0.000 0.548 0.451
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.548 0.451
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.548 0.451
E28.3 Primary ovarian failure
0.000 0.550 0.450
M07 Psoriatic and enteropathic arthropathies
0.006 0.550 0.444
J11 Influenza, virus not identified
0.000 0.550 0.450
N48.6 Balanitis xerotica obliterans
0.448 0.552 0.000
E23.2 Diabetes insipidus
0.000 0.556 0.444
E26.0 Primary hyperaldosteronism
0.000 0.557 0.443
M34.9 Systemic sclerosis, unspecified
0.000 0.563 0.437
J06.9 Acute upper respiratory infection, unspecified
0.000 0.563 0.437
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.564 0.436
J17 Pneumonia in diseases classified elsewhere
0.000 0.564 0.436
E28.9 Ovarian dysfunction, unspecified
0.000 0.564 0.436
E28.8 Other ovarian dysfunction
0.000 0.564 0.436
E28.1 Androgen excess
0.000 0.564 0.436
E28.0 Oestrogen excess
0.000 0.564 0.436
E11.3 With ophthalmic complications
0.000 0.565 0.435
E27.9 Disorder of adrenal gland, unspecified
0.000 0.565 0.435
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.567 0.433
E25 Adrenogenital disorders
0.000 0.567 0.432
M13 Other arthritis
0.000 0.567 0.433
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.567 0.432
J14 Pneumonia due to Haemophilus influenzae
0.000 0.568 0.432
E22 Hyperfunction of pituitary gland
0.000 0.569 0.431
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.575 0.425
E34.0 Carcinoid syndrome
0.000 0.575 0.425
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.577 0.422
J02 Acute pharyngitis
0.000 0.579 0.421
J01.9 Acute sinusitis, unspecified
0.000 0.580 0.420
G37 Other demyelinating diseases of central nervous system
0.000 0.581 0.419
E53.1 Pyridoxine deficiency
0.000 0.581 0.419
E53.0 Riboflavin deficiency
0.000 0.581 0.419
J96.9 Respiratory failure, unspecified
0.000 0.582 0.417
J96.1 Chronic respiratory failure
0.000 0.582 0.417
J96.0 Acute respiratory failure
0.000 0.582 0.417
E50.9 Vitamin A deficiency, unspecified
0.000 0.583 0.417
E50.8 Other manifestations of vitamin A deficiency
0.000 0.583 0.417
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.583 0.417
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.583 0.417
E50.5 Vitamin A deficiency with night blindness
0.000 0.583 0.417
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.583 0.417
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.583 0.417
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.583 0.417
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.583 0.417
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.583 0.417
E51.9 Thiamine deficiency, unspecified
0.000 0.583 0.417
E51.8 Other manifestations of thiamine deficiency
0.000 0.583 0.417
E51.2 Wernicke's encephalopathy
0.000 0.583 0.417
E51.1 Beriberi
0.000 0.583 0.417
E63.9 Nutritional deficiency, unspecified
0.000 0.583 0.417
E63.8 Other specified nutritional deficiencies
0.000 0.583 0.417
E63.1 Imbalance of constituents of food intake
0.000 0.583 0.417
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.583 0.417
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.583 0.417
E64.8 Sequelae of other nutritional deficiencies
0.000 0.583 0.417
E64.3 Sequelae of rickets
0.000 0.583 0.417
E64.2 Sequelae of vitamin C deficiency
0.000 0.583 0.417
E64.1 Sequelae of vitamin A deficiency
0.000 0.583 0.417
E64.0 Sequelae of protein-energy malnutrition
0.000 0.583 0.417
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.583 0.417
J09 Influenza due to certain identified influenza virus
0.000 0.583 0.417
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.584 0.416
J66 Airway disease due to specific organic dust
0.000 0.584 0.416
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.584 0.416
J62 Pneumoconiosis due to dust containing silica
0.000 0.584 0.416
J65 Pneumoconiosis associated with tuberculosis
0.000 0.584 0.416
E29.9 Testicular dysfunction, unspecified
0.000 0.584 0.416
E29.8 Other testicular dysfunction
0.000 0.584 0.416
E29.0 Testicular hyperfunction
0.000 0.584 0.416
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.585 0.414
J43.8 Other emphysema
0.000 0.586 0.414
J43.1 Panlobular emphysema
0.000 0.586 0.414

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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