TreeWAS – Variant ID: rs6945071

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.420	0.580	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.406	0.594	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.364	0.636	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.340	0.660	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.334	0.666	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.331	0.669	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.325	0.675	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.322	0.678	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.320	0.680	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.319	0.681	0.000
S80-S89 Injuries to the knee and lower leg	0.312	0.688	0.000
S82 Fracture of lower leg, including ankle	0.310	0.690	0.000
S82.6 Fracture of lateral malleolus	0.307	0.693	0.000
S82.60 Fracture of lateral malleolus (closed)	0.307	0.693	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.297	0.703	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.294	0.706	0.000
S90-S99 Injuries to the ankle and foot	0.288	0.712	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.284	0.716	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.283	0.717	0.000
S70-S79 Injuries to the hip and thigh	0.280	0.720	0.000
S10-S19 Injuries to the neck	0.272	0.728	0.000
S82.3 Fracture of lower end of tibia	0.270	0.730	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.270	0.730	0.000
S80 Superficial injury of lower leg	0.264	0.736	0.000
S92 Fracture of foot, except ankle	0.263	0.737	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.262	0.738	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.257	0.743	0.000
S00-S09 Injuries to the head	0.250	0.750	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.250	0.750	0.000
T86 Failure and rejection of transplanted organs and tissues	0.248	0.752	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.248	0.752	0.000
S82.4 Fracture of fibula alone	0.243	0.757	0.000
T00-T07 Injuries involving multiple body regions	0.242	0.758	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.239	0.761	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.238	0.762	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.237	0.763	0.000
S86 Injury of muscle and tendon at lower leg level	0.236	0.764	0.000
S92.0 Fracture of calcaneus	0.236	0.764	0.000
S82.1 Fracture of upper end of tibia	0.235	0.765	0.000
T87 Complications peculiar to reattachment and amputation	0.235	0.765	0.000
S82.30 Fracture of lower end of tibia (closed)	0.233	0.767	0.000
S14 Injury of nerves and spinal cord at neck level	0.233	0.767	0.000
S06 Intracranial injury	0.233	0.767	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.230	0.770	0.000
T33-T35 Frostbite	0.229	0.771	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.229	0.771	0.000
S79 Other and unspecified injuries of hip and thigh	0.229	0.771	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.228	0.772	0.000
T79-T79 Certain early complications of trauma	0.227	0.773	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.225	0.775	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.224	0.776	0.000
S88 Traumatic amputation of lower leg	0.223	0.776	0.000
S87 Crushing injury of lower leg	0.223	0.776	0.000
S85 Injury of blood vessels at lower leg level	0.223	0.776	0.000
S84 Injury of nerves at lower leg level	0.223	0.776	0.000
T23 Burn and corrosion of wrist and hand	0.223	0.777	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.223	0.777	0.000
S82.9 Fracture of lower leg, part unspecified	0.222	0.778	0.000
S82.7 Multiple fractures of lower leg	0.222	0.778	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.222	0.778	0.000
S82.61 Fracture of lateral malleolus (open)	0.220	0.780	0.000
T21 Burn and corrosion of trunk	0.220	0.780	0.000
S90 Superficial injury of ankle and foot	0.219	0.781	0.000
S70 Superficial injury of hip and thigh	0.218	0.782	0.000
S82.2 Fracture of shaft of tibia	0.218	0.782	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.218	0.782	0.000
S71 Open wound of hip and thigh	0.217	0.783	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.217	0.783	0.000
T66-T78 Other and unspecified effects of external causes	0.217	0.783	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.217	0.783	0.000
T82.1 Mechanical complication of cardiac electronic device	0.216	0.783	0.000
S92.00 Fracture of calcaneus (closed)	0.216	0.784	0.000
S32 Fracture of lumbar spine and pelvis	0.216	0.784	0.000
S80.8 Other superficial injuries of lower leg	0.215	0.785	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.214	0.786	0.000
S89 Other and unspecified injuries of lower leg	0.214	0.786	0.000
S40-S49 Injuries to the shoulder and upper arm	0.214	0.786	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.213	0.787	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.213	0.787	0.000
S92.5 Fracture of other toe	0.212	0.788	0.000
S82.31 Fracture of lower end of tibia (open)	0.211	0.789	0.000
S82.0 Fracture of patella	0.211	0.789	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.210	0.790	0.000
S12 Fracture of neck	0.210	0.790	0.000
T82.3 Mechanical complication of other vascular grafts	0.209	0.791	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.207	0.793	0.000
S98 Traumatic amputation of ankle and foot	0.206	0.794	0.000
S97 Crushing injury of ankle and foot	0.206	0.794	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.206	0.794	0.000
S95 Injury of blood vessels at ankle and foot level	0.206	0.794	0.000
S94 Injury of nerves at ankle and foot level	0.206	0.794	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.206	0.794	0.000
T20 Burn and corrosion of head and neck	0.206	0.794	0.000
S92.7 Multiple fractures of foot	0.206	0.794	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.206	0.794	0.000
S92.4 Fracture of great toe	0.205	0.795	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.204	0.796	0.000
T83.2 Mechanical complication of graft of urinary organ	0.204	0.796	0.000
S99 Other and unspecified injuries of ankle and foot	0.204	0.796	0.000
S50-S59 Injuries to the elbow and forearm	0.204	0.796	0.000
T25 Burn and corrosion of ankle and foot	0.203	0.797	0.000
S78 Traumatic amputation of hip and thigh	0.201	0.799	0.000
S77 Crushing injury of hip and thigh	0.201	0.799	0.000
S75 Injury of blood vessels at hip and thigh level	0.201	0.799	0.000
S74 Injury of nerves at hip and thigh level	0.201	0.799	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.201	0.799	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.200	0.800	0.000
S06.2 Diffuse brain injury	0.200	0.800	0.000
S80.9 Superficial injury of lower leg, unspecified	0.200	0.800	0.000
S19 Other and unspecified injuries of neck	0.196	0.803	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.196	0.804	0.000
S10 Superficial injury of neck	0.196	0.804	0.000
S82.8 Fractures of other parts of lower leg	0.196	0.804	0.000
S82.40 Fracture of fibula alone (closed)	0.195	0.805	0.000
S17 Crushing injury of neck	0.195	0.805	0.000
S15 Injury of blood vessels at neck level	0.195	0.805	0.000
S11 Open wound of neck	0.195	0.805	0.000
S18 Traumatic amputation at neck level	0.195	0.805	0.000
S16 Injury of muscle and tendon at neck level	0.195	0.805	0.000
S72 Fracture of femur	0.195	0.805	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.194	0.806	0.000
S32.5 Fracture of pubis	0.193	0.806	0.000
S06.4 Epidural haemorrhage	0.193	0.807	0.000
S79.9 Unspecified injury of hip and thigh	0.193	0.807	0.000
S02 Fracture of skull and facial bones	0.191	0.809	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.191	0.809	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.191	0.809	0.000
S80.7 Multiple superficial injuries of lower leg	0.189	0.811	0.000
S92.9 Fracture of foot, unspecified	0.189	0.811	0.000
S92.1 Fracture of talus	0.189	0.811	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.188	0.811	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.187	0.813	0.000
T00 Superficial injuries involving multiple body regions	0.186	0.813	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.186	0.814	0.000
S05 Injury of eye and orbit	0.186	0.814	0.000
S82.5 Fracture of medial malleolus	0.185	0.814	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.185	0.814	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.185	0.815	0.000
T86.0 Bone-marrow transplant rejection	0.184	0.815	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.184	0.816	0.000
T80.6 Other serum reactions	0.184	0.816	0.000
T80.5 Anaphylactic shock due to serum	0.184	0.816	0.000
T80.4 Rh incompatibility reaction	0.184	0.816	0.000
T80.3 ABO incompatibility reaction	0.184	0.816	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.184	0.816	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.183	0.816	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.183	0.816	0.000
S01 Open wound of head	0.184	0.816	0.000
S92.2 Fracture of other tarsal bone(s)	0.183	0.817	0.000
T91 Sequelae of injuries of neck and trunk	0.183	0.817	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.182	0.818	0.000
S82.10 Fracture of upper end of tibia (closed)	0.182	0.818	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.181	0.818	0.000
S91 Open wound of ankle and foot	0.181	0.819	0.000
S06.5 Traumatic subdural haemorrhage	0.180	0.820	0.000
S08 Traumatic amputation of part of head	0.180	0.820	0.000
S07 Crushing injury of head	0.180	0.820	0.000
S04 Injury of cranial nerves	0.180	0.820	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.180	0.820	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.180	0.820	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.179	0.821	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.178	0.822	0.000
T86.4 Liver transplant failure and rejection	0.178	0.822	0.000
T86.3 Heart-lung transplant failure and rejection	0.178	0.822	0.000
T86.2 Heart transplant failure and rejection	0.178	0.822	0.000
T93 Sequelae of injuries of lower limb	0.178	0.822	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.178	0.822	0.000
S37 Injury of urinary and pelvic organs	0.178	0.822	0.000
S36 Injury of intra-abdominal organs	0.178	0.822	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.178	0.822	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.178	0.822	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.178	0.822	0.000
S31 Open wound of abdomen, lower back and pelvis	0.178	0.822	0.000
S32.50 Fracture of pubis (closed)	0.177	0.823	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.177	0.823	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.177	0.823	0.000
S90.0 Contusion of ankle	0.177	0.823	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.177	0.823	0.000
S06.9 Intracranial injury, unspecified	0.176	0.824	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.176	0.824	0.000
S32.1 Fracture of sacrum	0.176	0.824	0.000
S92.50 Fracture of other toe (closed)	0.175	0.825	0.000
T21.3 Burn of third degree of trunk	0.175	0.825	0.000
S93.1 Dislocation of toe(s)	0.175	0.825	0.000
S82.41 Fracture of fibula alone (open)	0.174	0.825	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.174	0.826	0.000
T05 Traumatic amputations involving multiple body regions	0.174	0.826	0.000
T04 Crushing injuries involving multiple body regions	0.174	0.826	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.174	0.826	0.000
T02 Fractures involving multiple body regions	0.174	0.826	0.000
T01 Open wounds involving multiple body regions	0.174	0.826	0.000
T07 Unspecified multiple injuries	0.174	0.826	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.173	0.827	0.000
S70.0 Contusion of hip	0.173	0.827	0.000
S71.1 Open wound of thigh	0.173	0.827	0.000
S12.2 Fracture of other specified cervical vertebra	0.171	0.829	0.000
S43.0 Dislocation of shoulder joint	0.171	0.829	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.171	0.829	0.000
T11 Other injuries of upper limb, level unspecified	0.171	0.829	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.171	0.829	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.170	0.830	0.000
S51 Open wound of forearm	0.170	0.830	0.000
T36 Poisoning by systemic antibiotics	0.169	0.831	0.000
S86.0 Injury of Achilles tendon	0.169	0.831	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.169	0.831	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.169	0.831	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.169	0.831	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.169	0.831	0.000
S92.01 Fracture of calcaneus (open)	0.169	0.831	0.000
S82.11 Fracture of upper end of tibia (open)	0.169	0.831	0.000
T87.5 Necrosis of amputation stump	0.168	0.831	0.000
T87.4 Infection of amputation stump	0.168	0.831	0.000
T87.3 Neuroma of amputation stump	0.168	0.831	0.000
T87.2 Complications of other reattached body part	0.168	0.831	0.000
T87.1 Complications of reattached (part of) lower extremity	0.168	0.831	0.000
T87.0 Complications of reattached (part of) upper extremity	0.168	0.831	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.168	0.831	0.000
S80.0 Contusion of knee	0.167	0.832	0.000
S14.6 Injury of other and unspecified nerves of neck	0.167	0.833	0.000
S14.5 Injury of cervical sympathetic nerves	0.167	0.833	0.000
S14.4 Injury of peripheral nerves of neck	0.167	0.833	0.000
S14.3 Injury of brachial plexus	0.167	0.833	0.000
S14.2 Injury of nerve root of cervical spine	0.167	0.833	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.167	0.833	0.000
S06.7 Intracranial injury with prolonged coma	0.167	0.833	0.000
S06.1 Traumatic cerebral oedema	0.167	0.833	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.167	0.833	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.167	0.833	0.000
T86.1 Kidney transplant failure and rejection	0.167	0.833	0.000
S06.8 Other intracranial injuries	0.166	0.834	0.000
S06.3 Focal brain injury	0.165	0.835	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.165	0.835	0.000
S92.70 Multiple fractures of foot (closed)	0.165	0.835	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.165	0.835	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.165	0.835	0.000
T13 Other injuries of lower limb, level unspecified	0.165	0.835	0.000
T09 Other injuries of spine and trunk, level unspecified	0.165	0.835	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.165	0.835	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.165	0.835	0.000
T12 Fracture of lower limb, level unspecified	0.165	0.835	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.165	0.835	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.165	0.835	0.000
T10 Fracture of upper limb, level unspecified	0.165	0.835	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.165	0.835	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.165	0.835	0.000
T08 Fracture of spine, level unspecified	0.165	0.835	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.165	0.835	0.000
T28 Burn and corrosion of other internal organs	0.164	0.835	0.000
T27 Burn and corrosion of respiratory tract	0.164	0.835	0.000
T26 Burn and corrosion confined to eye and adnexa	0.164	0.835	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.164	0.835	0.000
T34 Frostbite with tissue necrosis	0.164	0.835	0.000
T33 Superficial frostbite	0.164	0.835	0.000
S79.8 Other specified injuries of hip and thigh	0.164	0.835	0.000
S79.7 Multiple injuries of hip and thigh	0.164	0.835	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.164	0.836	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.164	0.836	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.164	0.836	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.164	0.836	0.000
S32.3 Fracture of ilium	0.163	0.836	0.000
S92.41 Fracture of great toe (open)	0.163	0.837	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.161	0.838	0.000
T32 Corrosions classified according to extent of body surface involved	0.161	0.838	0.000
T30 Burn and corrosion, body region unspecified	0.161	0.838	0.000
T29 Burns and corrosions of multiple body regions	0.161	0.838	0.000
T23.3 Burn of third degree of wrist and hand	0.161	0.839	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.160	0.839	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.160	0.839	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.160	0.839	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.160	0.839	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.160	0.839	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.160	0.839	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.160	0.839	0.000
S84.8 Injury of other nerves at lower leg level	0.160	0.839	0.000
S84.7 Injury of multiple nerves at lower leg level	0.160	0.839	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.160	0.839	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.160	0.839	0.000
S84.0 Injury of tibial nerve at lower leg level	0.160	0.839	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.160	0.839	0.000
S85.8 Injury of other blood vessels at lower leg level	0.160	0.839	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.160	0.839	0.000
S85.5 Injury of popliteal vein	0.160	0.839	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.160	0.839	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.160	0.839	0.000
S85.2 Injury of peroneal artery	0.160	0.839	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.160	0.839	0.000
S85.0 Injury of popliteal artery	0.160	0.839	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.160	0.839	0.000
S87.0 Crushing injury of knee	0.160	0.839	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.160	0.839	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.160	0.839	0.000
S88.0 Traumatic amputation at knee level	0.160	0.839	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.160	0.840	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.160	0.840	0.000
T23.7 Corrosion of third degree of wrist and hand	0.160	0.840	0.000
T23.6 Corrosion of second degree of wrist and hand	0.160	0.840	0.000
T23.5 Corrosion of first degree of wrist and hand	0.160	0.840	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.160	0.840	0.000
T23.1 Burn of first degree of wrist and hand	0.160	0.840	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.160	0.840	0.000
T87.6 Other and unspecified complications of amputation stump	0.160	0.840	0.000
S82.71 Multiple fractures of lower leg (open)	0.159	0.840	0.000
S82.70 Multiple fractures of lower leg (closed)	0.159	0.840	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.159	0.840	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.159	0.840	0.000
S41 Open wound of shoulder and upper arm	0.159	0.841	0.000
S93.4 Sprain and strain of ankle	0.159	0.841	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.159	0.841	0.000
S93.5 Sprain and strain of toe(s)	0.159	0.841	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.159	0.841	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.159	0.841	0.000
S93.0 Dislocation of ankle joint	0.159	0.841	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.159	0.841	0.000
T14 Injury of unspecified body region	0.158	0.841	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.159	0.841	0.000
S01.4 Open wound of cheek and temporomandibular area	0.158	0.842	0.000
T21.7 Corrosion of third degree of trunk	0.158	0.842	0.000
T21.6 Corrosion of second degree of trunk	0.158	0.842	0.000
T21.5 Corrosion of first degree of trunk	0.158	0.842	0.000
T21.4 Corrosion of unspecified degree of trunk	0.158	0.842	0.000
T21.2 Burn of second degree of trunk	0.158	0.842	0.000
T21.1 Burn of first degree of trunk	0.158	0.842	0.000
T21.0 Burn of unspecified degree of trunk	0.158	0.842	0.000
T39.0 Salicylates	0.158	0.842	0.000
S82.21 Fracture of shaft of tibia (open)	0.158	0.842	0.000
S01.1 Open wound of eyelid and periocular area	0.158	0.842	0.000
S02.1 Fracture of base of skull	0.158	0.842	0.000
T31 Burns classified according to extent of body surface involved	0.157	0.842	0.000
S72.1 Pertrochanteric fracture	0.157	0.843	0.000
S72.4 Fracture of lower end of femur	0.157	0.843	0.000
S19.8 Other specified injuries of neck	0.157	0.843	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.157	0.843	0.000
S90.3 Contusion of other and unspecified parts of foot	0.157	0.843	0.000
S90.2 Contusion of toe(s) with damage to nail	0.157	0.843	0.000
S90.1 Contusion of toe(s) without damage to nail	0.157	0.843	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.157	0.843	0.000
S70.8 Other superficial injuries of hip and thigh	0.157	0.843	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.157	0.843	0.000
T95 Sequelae of burns, corrosions and frostbite	0.156	0.844	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.156	0.844	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.156	0.844	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.156	0.844	0.000
S71.7 Multiple open wounds of of hip and thigh	0.156	0.844	0.000
S71.0 Open wound of hip	0.156	0.844	0.000
S89.8 Other specified injuries of lower leg	0.156	0.844	0.000
S92.3 Fracture of metatarsal bone	0.156	0.844	0.000
T75 Effects of other external causes	0.156	0.844	0.000
T74 Maltreatment syndromes	0.156	0.844	0.000
T73 Effects of other deprivation	0.156	0.844	0.000
T70 Effects of air pressure and water pressure	0.156	0.844	0.000
T69 Other effects of reduced temperature	0.156	0.844	0.000
T67 Effects of heat and light	0.156	0.844	0.000
T71 Asphyxiation	0.156	0.844	0.000
T66 Unspecified effects of radiation	0.156	0.844	0.000
T78 Adverse effects, not elsewhere classified	0.156	0.844	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.155	0.845	0.000
S32.2 Fracture of coccyx	0.155	0.845	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.155	0.845	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.154	0.845	0.001
T91.3 Sequelae of injury of spinal cord	0.155	0.845	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.155	0.845	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.154	0.846	0.000
S89.7 Multiple injuries of lower leg	0.153	0.846	0.000
S89.1 Other specified injuries of lower leg	0.153	0.846	0.000
S89.0 Multiple injuries of lower leg	0.153	0.846	0.000
S48 Traumatic amputation of shoulder and upper arm	0.153	0.846	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.153	0.846	0.000
S44 Injury of nerves at shoulder and upper arm level	0.153	0.846	0.000
S47 Crushing injury of shoulder and upper arm	0.153	0.846	0.000
T93.2 Sequelae of other fractures of lower limb	0.153	0.847	0.000
S76.1 Injury of quadriceps muscle and tendon	0.153	0.847	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.153	0.847	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.153	0.847	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.153	0.847	0.000
S76.0 Injury of muscle and tendon of hip	0.153	0.847	0.000
S92.51 Fracture of other toe (open)	0.152	0.848	0.000
T23.2 Burn of second degree of wrist and hand	0.152	0.848	0.000
S82.01 Fracture of patella (open)	0.151	0.848	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.151	0.849	0.000
T20.2 Burn of second degree of head and neck	0.151	0.849	0.000
S02.2 Fracture of nasal bones	0.151	0.849	0.000
S12.9 Fracture of neck, part unspecified	0.150	0.849	0.000
S12.8 Fracture of other parts of neck	0.150	0.849	0.000
S12.0 Fracture of first cervical vertebra	0.150	0.849	0.000
S01.5 Open wound of lip and oral cavity	0.151	0.849	0.000
S56 Injury of muscle and tendon at forearm level	0.150	0.850	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.150	0.850	0.000
S82.20 Fracture of shaft of tibia (closed)	0.150	0.850	0.000
S70.1 Contusion of thigh	0.149	0.851	0.000
S82.81 Fractures of other parts of lower leg (open)	0.149	0.851	0.000
T39.1 4-Aminophenol derivatives	0.149	0.851	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.148	0.852	0.000
S94.8 Injury of other nerves at ankle and foot level	0.148	0.852	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.148	0.852	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.148	0.852	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.148	0.852	0.000
S94.1 Injury of medial plantar nerve	0.148	0.852	0.000
S94.0 Injury of lateral plantar nerve	0.148	0.852	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.148	0.852	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.148	0.852	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.148	0.852	0.000
S95.2 Injury of dorsal vein of foot	0.148	0.852	0.000
S95.1 Injury of plantar artery of foot	0.148	0.852	0.000
S95.0 Injury of dorsal artery of foot	0.148	0.852	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.148	0.852	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.148	0.852	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.148	0.852	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.148	0.852	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.148	0.852	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.148	0.852	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.148	0.852	0.000
S97.1 Crushing injury of toe(s)	0.148	0.852	0.000
S97.0 Crushing injury of ankle	0.148	0.852	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.148	0.852	0.000
S98.3 Traumatic amputation of other parts of foot	0.148	0.852	0.000
S98.2 Traumatic amputation of two or more toes	0.148	0.852	0.000
S98.1 Traumatic amputation of one toe	0.148	0.852	0.000
S98.0 Traumatic amputation of foot at ankle level	0.148	0.852	0.000
T20.7 Corrosion of third degree of head and neck	0.148	0.852	0.000
T20.6 Corrosion of second degree of head and neck	0.148	0.852	0.000
T20.5 Corrosion of first degree of head and neck	0.148	0.852	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.148	0.852	0.000
T20.3 Burn of third degree of head and neck	0.148	0.852	0.000
T20.1 Burn of first degree of head and neck	0.148	0.852	0.000
T20.0 Burn of unspecified degree of head and neck	0.148	0.852	0.000
S92.40 Fracture of great toe (closed)	0.148	0.852	0.000
S92.71 Multiple fractures of foot (open)	0.148	0.852	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.147	0.853	0.000
S06.0 Concussion	0.147	0.853	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.147	0.853	0.000
S12.7 Multiple fractures of cervical spine	0.147	0.853	0.000
S32.10 Fracture of sacrum (closed)	0.147	0.853	0.000
S50 Superficial injury of forearm	0.147	0.853	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.147	0.853	0.000
S99.8 Other specified injuries of ankle and foot	0.146	0.853	0.000
S99.7 Multiple injuries of ankle and foot	0.146	0.853	0.000
S59 Other and unspecified injuries of forearm	0.146	0.853	0.000
S58 Traumatic amputation of forearm	0.146	0.853	0.000
S57 Crushing injury of forearm	0.146	0.853	0.000
S55 Injury of blood vessels at forearm level	0.146	0.853	0.000
S54 Injury of nerves at forearm level	0.146	0.853	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.146	0.853	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.146	0.854	0.000
S90.8 Other superficial injuries of ankle and foot	0.146	0.854	0.000
T25.7 Corrosion of third degree of ankle and foot	0.146	0.854	0.000
T25.6 Corrosion of second degree of ankle and foot	0.146	0.854	0.000
T25.5 Corrosion of first degree of ankle and foot	0.146	0.854	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.146	0.854	0.000
T25.3 Burn of third degree of ankle and foot	0.146	0.854	0.000
T25.2 Burn of second degree of ankle and foot	0.146	0.854	0.000
T25.1 Burn of first degree of ankle and foot	0.146	0.854	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.146	0.854	0.000
S12.1 Fracture of second cervical vertebra	0.145	0.854	0.000
S43.1 Dislocation of acromioclavicular joint	0.145	0.855	0.000
S02.6 Fracture of mandible	0.145	0.855	0.000
T93.0 Sequelae of open wound of lower limb	0.145	0.855	0.000
S02.7 Multiple fractures involving skull and facial bones	0.145	0.855	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.145	0.855	0.000
S73.1 Sprain and strain of hip	0.144	0.856	0.000
S73.0 Dislocation of hip	0.144	0.856	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.144	0.856	0.000
S74.8 Injury of other nerves at hip and thigh level	0.144	0.856	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.144	0.856	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.144	0.856	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.144	0.856	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.144	0.856	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.144	0.856	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.144	0.856	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.144	0.856	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.144	0.856	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.144	0.856	0.000
S75.0 Injury of femoral artery	0.144	0.856	0.000
S77.2 Crushing injury of hip with thigh	0.144	0.856	0.000
S77.1 Crushing injury of thigh	0.144	0.856	0.000
S77.0 Crushing injury of hip	0.144	0.856	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.144	0.856	0.000
S78.1 Traumatic amputation at level between hip and knee	0.144	0.856	0.000
S78.0 Traumatic amputation at hip joint	0.144	0.856	0.000
T45.0 Antiallergic and antiemetic drugs	0.144	0.856	0.000
T58 Toxic effect of carbon monoxide	0.144	0.856	0.000
S99.9 Unspecified injury of ankle and foot	0.144	0.856	0.000
T98 Sequelae of other and unspecified effects of external causes	0.144	0.856	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.144	0.856	0.000
T39.4 Antirheumatics, not elsewhere classified	0.144	0.856	0.000
T39.2 Pyrazolone derivatives	0.144	0.856	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.144	0.856	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.143	0.856	0.000
T68 Hypothermia	0.143	0.857	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.142	0.858	0.000
S10.9 Superficial injury of neck, part unspecified	0.142	0.858	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.142	0.858	0.000
S19.7 Multiple injuries of neck	0.141	0.859	0.000
S89.9 Unspecified injury of lower leg	0.141	0.859	0.000
S10.8 Superficial injury of other parts of neck	0.141	0.859	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations