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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6953213
log Bayes Factor = 1.55719
Chromosome 7   position 7,313,485  (GRCh37) Explore rs6953213 on Ensembl!
Variant rs6953213 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F41 Other anxiety disorders
0.965 0.035 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.964 0.036 0.000
Chapter V Mental and behavioural disorders
0.963 0.037 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.961 0.039 0.000
# Top node
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.955 0.045 0.000
E70-E90 Metabolic disorders
0.954 0.046 0.000
E86 Volume depletion
0.954 0.046 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.952 0.048 0.000
F41.2 Mixed anxiety and depressive disorder
0.950 0.050 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.939 0.061 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.933 0.067 0.000
Chapter VIII Diseases of the ear and mastoid process
0.932 0.068 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.930 0.070 0.000
O60-O75 Complications of labour and delivery
0.922 0.078 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.920 0.080 0.000
T39.1 4-Aminophenol derivatives
0.917 0.083 0.000
F30-F39 Mood [affective] disorders
0.908 0.092 0.000
Chapter VI Diseases of the nervous system
0.901 0.099 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.887 0.113 0.000
F32 Depressive episode
0.885 0.115 0.000
F41.9 Anxiety disorder, unspecified
0.882 0.118 0.000
G40-G47 Episodic and paroxysmal disorders
0.878 0.122 0.000
E83 Disorders of mineral metabolism
0.877 0.123 0.000
H90-H95 Other disorders of ear
0.874 0.126 0.000
F41.1 Generalised anxiety disorder
0.874 0.126 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.864 0.136 0.000
F32.9 Depressive episode, unspecified
0.864 0.136 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.862 0.138 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.855 0.145 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.854 0.146 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.850 0.150 0.000
E20-E35 Disorders of other endocrine glands
0.842 0.158 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.842 0.158 0.000
H65-H75 Diseases of middle ear and mastoid
0.839 0.161 0.000
F60-F69 Disorders of adult personality and behaviour
0.839 0.161 0.000
H93 Other disorders of ear, not elsewhere classified
0.830 0.170 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.828 0.172 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.816 0.184 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
H93.1 Tinnitus
0.798 0.202 0.000
T81 Complications of procedures, not elsewhere classified
0.798 0.202 0.000
E88 Other metabolic disorders
0.789 0.211 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.784 0.216 0.000
S80-S89 Injuries to the knee and lower leg
0.781 0.219 0.000
E83.1 Disorders of iron metabolism
0.772 0.228 0.000
H90 Conductive and sensorineural hearing loss
0.772 0.228 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.770 0.230 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.769 0.231 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.768 0.232 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.768 0.232 0.000
H60-H62 Diseases of external ear
0.767 0.233 0.000
F32.1 Moderate depressive episode
0.765 0.235 0.000
T39.0 Salicylates
0.765 0.235 0.000
H66 Suppurative and unspecified otitis media
0.761 0.239 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.758 0.242 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.754 0.246 0.000
O80-O84 Delivery
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.752 0.248 0.000
T87 Complications peculiar to reattachment and amputation
0.751 0.249 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.750 0.250 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.749 0.251 0.000
F60 Specific personality disorders
0.749 0.251 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.745 0.255 0.000
T36 Poisoning by systemic antibiotics
0.743 0.257 0.000
O62 Abnormalities of forces of labour
0.742 0.258 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.740 0.260 0.000
G40 Epilepsy
0.735 0.265 0.000
E27 Other disorders of adrenal gland
0.734 0.266 0.000
S50-S59 Injuries to the elbow and forearm
0.734 0.266 0.000
E83.3 Disorders of phosphorus metabolism
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.731 0.269 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.729 0.271 0.000
E85 Amyloidosis
0.727 0.273 0.000
F40 Phobic anxiety disorders
0.723 0.277 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.718 0.282 0.000
Chapter XX External causes of morbidity and mortality
0.715 0.285 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.713 0.287 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
F20 Schizophrenia
0.711 0.289 0.000
H66.9 Otitis media, unspecified
0.709 0.291 0.000
O85-O92 Complications predominantly related to the puerperium
0.709 0.291 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
S10-S19 Injuries to the neck
0.703 0.296 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.699 0.301 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.698 0.302 0.000
O71 Other obstetric trauma
0.697 0.303 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.694 0.306 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.694 0.306 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.694 0.306 0.000
F41.8 Other specified anxiety disorders
0.692 0.308 0.000
F41.3 Other mixed anxiety disorders
0.692 0.308 0.000
F48 Other neurotic disorders
0.691 0.309 0.000
F44 Dissociative [conversion] disorders
0.691 0.309 0.000
F42 Obsessive-compulsive disorder
0.691 0.309 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.691 0.309 0.000
F70-F79 Mental retardation
0.691 0.309 0.000
O00-O08 Pregnancy with abortive outcome
0.691 0.309 0.000
T33-T35 Frostbite
0.689 0.311 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.689 0.311 0.000
T00-T07 Injuries involving multiple body regions
0.689 0.311 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.688 0.312 0.000
Chapter XIV Diseases of the genitourinary system
0.687 0.313 0.000
O66 Other obstructed labour
0.687 0.313 0.000
T79-T79 Certain early complications of trauma
0.686 0.314 0.000
O73 Retained placenta and membranes, without haemorrhage
0.685 0.314 0.000
E84 Cystic fibrosis
0.684 0.316 0.000
E79 Disorders of purine and pyrimidine metabolism
0.684 0.316 0.000
E77 Disorders of glycoprotein metabolism
0.684 0.316 0.000
E76 Disorders of glycosaminoglycan metabolism
0.684 0.316 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.684 0.316 0.000
E74 Other disorders of carbohydrate metabolism
0.684 0.316 0.000
E73 Lactose intolerance
0.684 0.316 0.000
E72 Other disorders of amino-acid metabolism
0.684 0.316 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.684 0.316 0.000
E70 Disorders of aromatic amino-acid metabolism
0.684 0.316 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.684 0.316 0.000
H74 Other disorders of middle ear and mastoid
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.683 0.317 0.000
N10-N16 Renal tubulo-interstitial diseases
0.682 0.318 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.682 0.318 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.318 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.682 0.318 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.682 0.318 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.682 0.318 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
S82 Fracture of lower leg, including ankle
0.682 0.318 0.000
F43 Reaction to severe stress, and adjustment disorders
0.682 0.318 0.000
S60-S69 Injuries to the wrist and hand
0.681 0.319 0.000
S70-S79 Injuries to the hip and thigh
0.676 0.324 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.325 0.000
F60.3 Emotionally unstable personality disorder
0.675 0.325 0.000
G43 Migraine
0.675 0.325 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.673 0.326 0.000
T39.4 Antirheumatics, not elsewhere classified
0.673 0.326 0.000
T39.2 Pyrazolone derivatives
0.673 0.326 0.000
T86 Failure and rejection of transplanted organs and tissues
0.672 0.328 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.671 0.329 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.671 0.329 0.000
F45 Somatoform disorders
0.669 0.331 0.000
E28 Ovarian dysfunction
0.668 0.332 0.000
T82.1 Mechanical complication of cardiac electronic device
0.668 0.332 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.665 0.335 0.000
Chapter XXII Codes for special purposes
0.664 0.335 0.000
N13 Obstructive and reflux uropathy
0.664 0.336 0.000
E83.4 Disorders of magnesium metabolism
0.662 0.338 0.000
O74 Complications of anaesthesia during labour and delivery
0.661 0.339 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.661 0.339 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.661 0.339 0.000
O61 Failed induction of labour
0.661 0.339 0.000
O60 Preterm delivery
0.661 0.339 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.659 0.341 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.659 0.341 0.000
G35 Multiple sclerosis
0.658 0.342 0.000
T51 Toxic effect of alcohol
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.345 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.653 0.347 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.653 0.347 0.000
F38 Other mood [affective] disorders
0.651 0.349 0.000
F30 Manic episode
0.651 0.349 0.000
F39 Unspecified mood [affective] disorder
0.651 0.349 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.649 0.350 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.648 0.351 0.000
F23 Acute and transient psychotic disorders
0.645 0.354 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.645 0.355 0.000
H90.2 Conductive hearing loss, unspecified
0.643 0.357 0.000
E00-E07 Disorders of thyroid gland
0.643 0.357 0.000
E34 Other endocrine disorders
0.642 0.358 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.641 0.359 0.000
F99-F99 Unspecified mental disorder
0.640 0.360 0.000
H72 Perforation of tympanic membrane
0.640 0.360 0.000
F80-F89 Disorders of psychological development
0.640 0.360 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.640 0.360 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.639 0.361 0.000
G37 Other demyelinating diseases of central nervous system
0.638 0.362 0.000
H60 Otitis externa
0.637 0.363 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.635 0.365 0.000
F32.8 Other depressive episodes
0.634 0.365 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
H70 Mastoiditis and related conditions
0.632 0.368 0.000
G41 Status epilepticus
0.631 0.368 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.632 0.368 0.000
O72 Postpartum haemorrhage
0.631 0.369 0.000
E29 Testicular dysfunction
0.630 0.370 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.630 0.370 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.629 0.371 0.000
E83.8 Other disorders of mineral metabolism
0.629 0.371 0.000
E83.2 Disorders of zinc metabolism
0.629 0.371 0.000
E83.0 Disorders of copper metabolism
0.629 0.371 0.000
T56 Toxic effect of metals
0.628 0.372 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.628 0.372 0.000
E27.1 Primary adrenocortical insufficiency
0.628 0.372 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.627 0.373 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.627 0.373 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.623 0.376 0.000
S81 Open wound of lower leg
0.623 0.377 0.000
F25 Schizoaffective disorders
0.621 0.379 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.621 0.379 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.618 0.382 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.618 0.382 0.000
G45.0 Vertebro-basilar artery syndrome
0.618 0.382 0.000
T93 Sequelae of injuries of lower limb
0.617 0.383 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.615 0.385 0.000
G45.4 Transient global amnesia
0.615 0.385 0.000
O62.2 Other uterine inertia
0.613 0.387 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.612 0.387 0.000
E83.5 Disorders of calcium metabolism
0.612 0.388 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.612 0.388 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.611 0.388 0.000
S20 Superficial injury of thorax
0.611 0.389 0.000
O80 Single spontaneous delivery
0.611 0.389 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.608 0.392 0.000
T98 Sequelae of other and unspecified effects of external causes
0.607 0.393 0.000
G70-G73 Diseases of myoneural junction and muscle
0.607 0.393 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.605 0.395 0.000
S29 Other and unspecified injuries of thorax
0.604 0.396 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.604 0.396 0.000
E32 Diseases of thymus
0.604 0.396 0.000
E31 Polyglandular dysfunction
0.604 0.396 0.000
E30 Disorders of puberty, not elsewhere classified
0.604 0.396 0.000
E26 Hyperaldosteronism
0.604 0.396 0.000
E25 Adrenogenital disorders
0.604 0.396 0.000
E24 Cushing's syndrome
0.604 0.396 0.000
E20 Hypoparathyroidism
0.604 0.396 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.604 0.396 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.604 0.396 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.604 0.396 0.000
T82.3 Mechanical complication of other vascular grafts
0.604 0.396 0.000
E80.4 Gilbert's syndrome
0.603 0.397 0.000
T78 Adverse effects, not elsewhere classified
0.602 0.398 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.601 0.398 0.000
H68 Eustachian salpingitis and obstruction
0.601 0.398 0.000
H67 Otitis media in diseases classified elsewhere
0.601 0.398 0.000
N13.3 Other and unspecified hydronephrosis
0.601 0.399 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.601 0.399 0.000
F68 Other disorders of adult personality and behaviour
0.601 0.399 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.601 0.399 0.000
F65 Disorders of sexual preference
0.601 0.399 0.000
F64 Gender identity disorders
0.601 0.399 0.000
F63 Habit and impulse disorders
0.601 0.399 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.601 0.399 0.000
F69 Unspecified disorder of adult personality and behaviour
0.601 0.399 0.000
F61 Mixed and other personality disorders
0.601 0.399 0.000
F32.0 Mild depressive episode
0.599 0.401 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.598 0.402 0.000
O02 Other abnormal products of conception
0.597 0.403 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.596 0.403 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.596 0.404 0.000
F20.0 Paranoid schizophrenia
0.595 0.405 0.000
H93.9 Disorder of ear, unspecified
0.595 0.405 0.000
H93.8 Other specified disorders of ear
0.595 0.405 0.000
H93.3 Disorders of acoustic nerve
0.595 0.405 0.000
H93.2 Other abnormal auditory perceptions
0.595 0.405 0.000
H93.0 Degenerative and vascular disorders of ear
0.595 0.405 0.000
H69 Other disorders of Eustachian tube
0.595 0.405 0.000
T87.4 Infection of amputation stump
0.594 0.406 0.000
T36.0 Penicillins
0.594 0.406 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.593 0.406 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.593 0.406 0.000
G30-G32 Other degenerative diseases of the nervous system
0.593 0.407 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.592 0.408 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.591 0.409 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.587 0.413 0.000
F28 Other nonorganic psychotic disorders
0.585 0.415 0.000
F24 Induced delusional disorder
0.585 0.415 0.000
F21 Schizotypal disorder
0.585 0.415 0.000
G43.1 Migraine with aura [classical migraine]
0.584 0.416 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.581 0.419 0.000
F20.9 Schizophrenia, unspecified
0.580 0.420 0.000
E22 Hyperfunction of pituitary gland
0.575 0.424 0.000
G40.5 Special epileptic syndromes
0.575 0.425 0.000
T87.6 Other and unspecified complications of amputation stump
0.575 0.425 0.000
E27.9 Disorder of adrenal gland, unspecified
0.575 0.425 0.000
S51 Open wound of forearm
0.574 0.426 0.000
T65 Toxic effect of other and unspecified substances
0.574 0.426 0.000
T62 Toxic effect of other noxious substances eaten as food
0.574 0.426 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.574 0.426 0.000
T60 Toxic effect of pesticides
0.574 0.426 0.000
T59 Toxic effect of other gases, fumes and vapours
0.574 0.426 0.000
T57 Toxic effect of other inorganic substances
0.574 0.426 0.000
T54 Toxic effect of corrosive substances
0.574 0.426 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.574 0.426 0.000
T52 Toxic effect of organic solvents
0.574 0.426 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.574 0.426 0.000
T58 Toxic effect of carbon monoxide
0.574 0.426 0.000
T55 Toxic effect of soaps and detergents
0.574 0.426 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.573 0.427 0.000
S60 Superficial injury of wrist and hand
0.573 0.427 0.000
T81.9 Unspecified complication of procedure
0.572 0.428 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.572 0.428 0.000
H65 Nonsuppurative otitis media
0.572 0.428 0.000
H90.5 Sensorineural hearing loss, unspecified
0.569 0.431 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.569 0.431 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.569 0.431 0.000
H61 Other disorders of external ear
0.568 0.432 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.568 0.432 0.000
G81 Hemiplegia
0.567 0.433 0.000
T31 Burns classified according to extent of body surface involved
0.567 0.433 0.000
E88.9 Metabolic disorder, unspecified
0.566 0.434 0.000
E88.8 Other specified metabolic disorders
0.566 0.434 0.000
E88.3 Tumour lysis syndrome
0.566 0.434 0.000
E88.2 Lipomatosis, not elsewhere classified
0.566 0.434 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.566 0.434 0.000
H90.3 Sensorineural hearing loss, bilateral
0.566 0.434 0.000
F60.9 Personality disorder, unspecified
0.565 0.435 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.565 0.435 0.000
O82 Single delivery by Caesarean section
0.565 0.435 0.000
T63 Toxic effect of contact with venomous animals
0.564 0.436 0.000
S81.9 Open wound of lower leg, part unspecified
0.564 0.436 0.000
E85.9 Amyloidosis, unspecified
0.564 0.436 0.000
G36 Other acute disseminated demyelination
0.562 0.438 0.000
T23 Burn and corrosion of wrist and hand
0.562 0.438 0.000
F33 Recurrent depressive disorder
0.561 0.438 0.000
S88 Traumatic amputation of lower leg
0.560 0.440 0.000
S87 Crushing injury of lower leg
0.560 0.440 0.000
S86 Injury of muscle and tendon at lower leg level
0.560 0.440 0.000
S85 Injury of blood vessels at lower leg level
0.560 0.440 0.000
S84 Injury of nerves at lower leg level
0.560 0.440 0.000
N99-N99 Other disorders of the genitourinary system
0.558 0.442 0.000
G45.3 Amaurosis fugax
0.558 0.442 0.000
G00 Bacterial meningitis, not elsewhere classified
0.557 0.442 0.000
S80 Superficial injury of lower leg
0.557 0.443 0.000
S89 Other and unspecified injuries of lower leg
0.557 0.443 0.000
S82.3 Fracture of lower end of tibia
0.557 0.443 0.000
S82.0 Fracture of patella
0.557 0.443 0.000
N13.4 Hydroureter
0.557 0.443 0.000
N00-N08 Glomerular diseases
0.556 0.444 0.000
F34.1 Dysthymia
0.556 0.444 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.555 0.445 0.000
W50-W64 Exposure to animate mechanical forces
0.555 0.445 0.000
G20-G26 Extrapyramidal and movement disorders
0.554 0.446 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.553 0.446 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.553 0.446 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.553 0.446 0.000
H90.0 Conductive hearing loss, bilateral
0.553 0.446 0.000
T85.2 Mechanical complication of intraocular lens
0.553 0.447 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.552 0.447 0.000
S40-S49 Injuries to the shoulder and upper arm
0.551 0.449 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.551 0.449 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.551 0.449 0.000
T46.7 Peripheral vasodilators
0.551 0.449 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.551 0.449 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.551 0.449 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.551 0.449 0.000
T46.1 Calcium-channel blockers
0.551 0.449 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.551 0.449 0.000
N25-N29 Other disorders of kidney and ureter
0.551 0.449 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.551 0.449 0.000
F51 Nonorganic sleep disorders
0.551 0.449 0.000
F50 Eating disorders
0.551 0.449 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.551 0.449 0.000
F55 Abuse of non-dependence-producing substances
0.551 0.449 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.551 0.449 0.000
T95 Sequelae of burns, corrosions and frostbite
0.550 0.450 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.550 0.450 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.550 0.450 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.550 0.450 0.000
H72.0 Central perforation of tympanic membrane
0.550 0.450 0.000
F40.2 Specific (isolated) phobias
0.550 0.450 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.550 0.450 0.000
G80 Infantile cerebral palsy
0.549 0.450 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.549 0.451 0.000
E23 Hypofunction and other disorders of pituitary gland
0.549 0.451 0.000
H73 Other disorders of tympanic membrane
0.548 0.452 0.000
E28.3 Primary ovarian failure
0.547 0.453 0.000
H66.4 Suppurative otitis media, unspecified
0.546 0.454 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.546 0.454 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.546 0.454 0.000
H66.0 Acute suppurative otitis media
0.546 0.454 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.545 0.455 0.000
F22 Persistent delusional disorders
0.545 0.455 0.000
G90-G99 Other disorders of the nervous system
0.544 0.455 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.544 0.456 0.000
O70 Perineal laceration during delivery
0.544 0.456 0.000
G44 Other headache syndromes
0.543 0.457 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.542 0.458 0.000
O90 Complications of the puerperium, not elsewhere classified
0.541 0.459 0.000
H71 Cholesteatoma of middle ear
0.541 0.459 0.000
O84 Multiple delivery
0.540 0.460 0.000
O83 Other assisted single delivery
0.540 0.460 0.000
O81 Single delivery by forceps and vacuum extractor
0.540 0.460 0.000
X50-X57 Overexertion, travel and privation
0.540 0.460 0.000
S91 Open wound of ankle and foot
0.539 0.461 0.000
T75 Effects of other external causes
0.539 0.461 0.000
T74 Maltreatment syndromes
0.539 0.461 0.000
T73 Effects of other deprivation
0.539 0.461 0.000
T70 Effects of air pressure and water pressure
0.539 0.461 0.000
T69 Other effects of reduced temperature
0.539 0.461 0.000
T67 Effects of heat and light
0.539 0.461 0.000
T71 Asphyxiation
0.539 0.461 0.000
T68 Hypothermia
0.539 0.461 0.000
T66 Unspecified effects of radiation
0.539 0.461 0.000
T90 Sequelae of injuries of head
0.539 0.461 0.000
H60.8 Other otitis externa
0.539 0.461 0.000
N11 Chronic tubulo-interstitial nephritis
0.539 0.461 0.000
T87.5 Necrosis of amputation stump
0.539 0.461 0.000
T87.3 Neuroma of amputation stump
0.539 0.461 0.000
T87.2 Complications of other reattached body part
0.539 0.461 0.000
T87.1 Complications of reattached (part of) lower extremity
0.539 0.461 0.000
T87.0 Complications of reattached (part of) upper extremity
0.539 0.461 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.538 0.462 0.000
E80.6 Other disorders of bilirubin metabolism
0.538 0.462 0.000
E80.5 Crigler-Najjar syndrome
0.538 0.462 0.000
E80.3 Defects of catalase and peroxydase
0.538 0.462 0.000
E80.2 Other porphyria
0.538 0.462 0.000
E80.1 Porphyria cutanea tarda
0.538 0.462 0.000
E80.0 Hereditary erythropoietic porphyria
0.538 0.462 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.538 0.462 0.000
T91 Sequelae of injuries of neck and trunk
0.537 0.462 0.000
E27.8 Other specified disorders of adrenal gland
0.537 0.463 0.000
F60.8 Other specific personality disorders
0.537 0.463 0.000
F60.7 Dependent personality disorder
0.537 0.463 0.000
F60.6 Anxious [avoidant] personality disorder
0.537 0.463 0.000
F60.5 Anankastic personality disorder
0.537 0.463 0.000
F60.4 Histrionic personality disorder
0.537 0.463 0.000
F60.2 Dissocial personality disorder
0.537 0.463 0.000
F60.1 Schizoid personality disorder
0.537 0.463 0.000
F60.0 Paranoid personality disorder
0.537 0.463 0.000
E46 Unspecified protein-energy malnutrition
0.537 0.463 0.000
O71.4 Obstetric high vaginal laceration alone
0.536 0.464 0.000
S62 Fracture at wrist and hand level
0.536 0.464 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.535 0.465 0.000
H91 Other hearing loss
0.535 0.465 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.534 0.466 0.000
O97 Death from sequelae of direct obstetric causes
0.534 0.466 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.534 0.466 0.000
O95 Obstetric death of unspecified cause
0.534 0.466 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.534 0.466 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.534 0.466 0.000
S26 Injury of heart
0.534 0.466 0.000
S25 Injury of blood vessels of thorax
0.534 0.466 0.000
S24 Injury of nerves and spinal cord at thorax level
0.534 0.466 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.534 0.466 0.000
S21 Open wound of thorax
0.534 0.466 0.000
G61 Inflammatory polyneuropathy
0.533 0.467 0.000
T36.9 Systemic antibiotic, unspecified
0.533 0.467 0.000
T36.8 Other systemic antibiotics
0.533 0.467 0.000
T36.7 Antifungal antibiotics, systemically used
0.533 0.467 0.000
T36.6 Rifamycins
0.533 0.467 0.000
T36.5 Aminoglycosides
0.533 0.467 0.000
T36.4 Tetracyclines
0.533 0.467 0.000
T36.3 Macrolides
0.533 0.467 0.000
T36.2 Chloramphenicol group
0.533 0.467 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.533 0.467 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.533 0.467 0.000
O62.9 Abnormality of forces of labour, unspecified
0.532 0.468 0.000
O62.8 Other abnormalities of forces of labour
0.532 0.468 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.532 0.468 0.000
O62.3 Precipitate labour
0.532 0.468 0.000
O62.1 Secondary uterine inertia
0.532 0.468 0.000
O62.0 Primary inadequate contractions
0.532 0.468 0.000
H66.3 Other chronic suppurative otitis media
0.531 0.469 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.531 0.469 0.000
S50 Superficial injury of forearm
0.531 0.469 0.000
O02.1 Missed abortion
0.531 0.469 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.530 0.470 0.000
S82.5 Fracture of medial malleolus
0.530 0.470 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.527 0.472 0.000
F52.2 Failure of genital response
0.527 0.473 0.000
S10 Superficial injury of neck
0.527 0.473 0.000
T51.0 Ethanol
0.527 0.473 0.000
G40.8 Other epilepsy
0.527 0.473 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.527 0.473 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.527 0.473 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.527 0.473 0.000
E27.5 Adrenomedullary hyperfunction
0.526 0.473 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.526 0.473 0.000
E27.2 Addisonian crisis
0.526 0.473 0.000
E27.0 Other adrenocortical overactivity
0.526 0.473 0.000
S59 Other and unspecified injuries of forearm
0.526 0.474 0.000
S58 Traumatic amputation of forearm
0.526 0.474 0.000
S57 Crushing injury of forearm
0.526 0.474 0.000
S56 Injury of muscle and tendon at forearm level
0.526 0.474 0.000
S55 Injury of blood vessels at forearm level
0.526 0.474 0.000
S54 Injury of nerves at forearm level
0.526 0.474 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.526 0.474 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.526 0.474 0.000
H80-H83 Diseases of inner ear
0.525 0.475 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.525 0.475 0.000
T32 Corrosions classified according to extent of body surface involved
0.524 0.475 0.000
T30 Burn and corrosion, body region unspecified
0.524 0.475 0.000
T29 Burns and corrosions of multiple body regions
0.524 0.475 0.000
T92 Sequelae of injuries of upper limb
0.524 0.476 0.000
V80-V89 Other land transport accidents
0.524 0.476 0.000
E06 Thyroiditis
0.523 0.477 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.523 0.477 0.000
N13.6 Pyonephrosis
0.523 0.477 0.000
T25 Burn and corrosion of ankle and foot
0.522 0.477 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.522 0.477 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.522 0.477 0.000
T21 Burn and corrosion of trunk
0.522 0.477 0.000
T20 Burn and corrosion of head and neck
0.522 0.477 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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