TreeWAS – Variant ID: rs7031325

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K74.6 Other and unspecified cirrhosis of liver	0.106	0.894	0.000
K74 Fibrosis and cirrhosis of liver	0.099	0.901	0.000
K70-K77 Diseases of liver	0.095	0.905	0.000
K76 Other diseases of liver	0.091	0.909	0.000
K74.0 Hepatic fibrosis	0.090	0.910	0.000
K70 Alcoholic liver disease	0.090	0.910	0.000
K76.9 Liver disease, unspecified	0.089	0.911	0.000
K76.6 Portal hypertension	0.085	0.915	0.000
K70.1 Alcoholic hepatitis	0.084	0.916	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.922	0.078
K70.3 Alcoholic cirrhosis of liver	0.078	0.922	0.000
K70.9 Alcoholic liver disease, unspecified	0.077	0.923	0.000
K75 Other inflammatory liver diseases	0.077	0.923	0.000
K75.8 Other specified inflammatory liver diseases	0.077	0.923	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.073	0.927	0.000
K71 Toxic liver disease	0.073	0.927	0.000
K74.4 Secondary biliary cirrhosis	0.071	0.929	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.071	0.929	0.000
K74.1 Hepatic sclerosis	0.071	0.929	0.000
K74.5 Biliary cirrhosis, unspecified	0.069	0.930	0.000
K77 Liver disorders in diseases classified elsewhere	0.068	0.932	0.000
K76.7 Hepatorenal syndrome	0.066	0.934	0.000
K76.5 Hepatic veno-occlusive disease	0.066	0.934	0.000
K76.4 Peliosis hepatis	0.066	0.934	0.000
K76.3 Infarction of liver	0.066	0.934	0.000
K76.2 Central haemorrhagic necrosis of liver	0.066	0.934	0.000
K73 Chronic hepatitis, not elsewhere classified	0.064	0.936	0.000
K76.1 Chronic passive congestion of liver	0.061	0.939	0.000
S02 Fracture of skull and facial bones	0.061	0.939	0.000
S02.6 Fracture of mandible	0.059	0.941	0.000
S02.2 Fracture of nasal bones	0.058	0.942	0.000
S02.60 Fracture of mandible (closed)	0.058	0.942	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.057	0.943	0.000
S02.20 Fracture of nasal bones (closed)	0.057	0.943	0.000
S02.8 Fractures of other skull and facial bones	0.056	0.944	0.000
K76.8 Other specified diseases of liver	0.056	0.944	0.000
K75.2 Nonspecific reactive hepatitis	0.055	0.944	0.000
K75.1 Phlebitis of portal vein	0.055	0.944	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.055	0.945	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.053	0.947	0.000
K71.9 Toxic liver disease, unspecified	0.052	0.947	0.000
K71.8 Toxic liver disease with other disorders of liver	0.052	0.947	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.052	0.947	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.052	0.947	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.052	0.947	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.052	0.947	0.000
K71.2 Toxic liver disease with acute hepatitis	0.052	0.947	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.052	0.947	0.000
K71.0 Toxic liver disease with cholestasis	0.052	0.947	0.000
S02.0 Fracture of vault of skull	0.052	0.947	0.000
K73.9 Chronic hepatitis, unspecified	0.051	0.949	0.000
K75.4 Autoimmune hepatitis	0.051	0.949	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.050	0.949	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.050	0.950	0.000
S02.5 Fracture of tooth	0.050	0.950	0.000
S02.1 Fracture of base of skull	0.050	0.950	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.950	0.050
K77.8 Liver disorders in other diseases classified elsewhere	0.049	0.951	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.049	0.951	0.000
S02.00 Fracture of vault of skull (closed)	0.047	0.953	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.953	0.047
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.046	0.954	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.046	0.954	0.000
K75.9 Inflammatory liver disease, unspecified	0.045	0.955	0.000
S02.4 Fracture of malar and maxillary bones	0.045	0.955	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.955	0.045
K73.8 Other chronic hepatitis, not elsewhere classified	0.044	0.956	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.043	0.957	0.000
S02.61 Fracture of mandible (open)	0.042	0.958	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.958	0.042
S02.50 Fracture of tooth (closed)	0.042	0.958	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.958	0.042
K72 Hepatic failure, not elsewhere classified	0.042	0.958	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.958	0.042
C83.3 Large cell (diffuse)	0.000	0.958	0.042
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.958	0.042
S02.3 Fracture of orbital floor	0.041	0.959	0.000
S02.81 Fractures of other skull and facial bones (open)	0.041	0.959	0.000
S02.11 Fracture of base of skull (open)	0.040	0.960	0.000
S02.21 Fracture of nasal bones (open)	0.040	0.960	0.000
K70.4 Alcoholic hepatic failure	0.039	0.960	0.000
S02.10 Fracture of base of skull (closed)	0.039	0.961	0.000
C82.2 Large cell, follicular	0.000	0.962	0.038
S02.01 Fracture of vault of skull (open)	0.038	0.962	0.000
K70.0 Alcoholic fatty liver	0.036	0.964	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.036	0.964	0.000
S02.51 Fracture of tooth (open)	0.036	0.964	0.000
C88 Malignant immunoproliferative diseases	0.000	0.964	0.036
S02.7 Multiple fractures involving skull and facial bones	0.035	0.965	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.035	0.965	0.000
S82.6 Fracture of lateral malleolus	0.000	0.965	0.034
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.966	0.034
C82.4 Follicular lymphoma grade IIIb	0.000	0.966	0.034
C82.6 Cutaneous follicle centre lymphoma	0.000	0.966	0.034
C82.5 Diffuse follicle centre lymphoma	0.000	0.966	0.034
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.966	0.034
S02.40 Fracture of malar and maxillary bones (closed)	0.033	0.967	0.000
C83.0 Small cell (diffuse)	0.000	0.968	0.032
S02.41 Fracture of malar and maxillary bones (open)	0.032	0.968	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.968	0.032
C82.3 Follicular lymphoma grade IIIa	0.000	0.968	0.032
K76.0 Fatty (change of) liver, not elsewhere classified	0.032	0.968	0.000
K74.3 Primary biliary cirrhosis	0.032	0.968	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.969	0.031
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.969	0.031
C85.0 Lymphosarcoma	0.000	0.969	0.031
C83.7 Burkitt's tumour	0.000	0.969	0.030
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.969	0.030
C94 Other leukaemias of specified cell type	0.000	0.969	0.030
C82.0 Small cleaved cell, follicular	0.000	0.969	0.030
C81 Hodgkin's disease	0.000	0.970	0.030
C83.6 Undifferentiated (diffuse)	0.000	0.970	0.030
C83.5 Lymphoblastic (diffuse)	0.000	0.970	0.030
C83.4 Immunoblastic (diffuse)	0.000	0.970	0.030
C83.2 Mixed small and large cell (diffuse)	0.000	0.970	0.030
S02.31 Fracture of orbital floor (open)	0.029	0.971	0.000
C84.0 Mycosis fungoides	0.000	0.971	0.029
C83.1 Small cleaved cell (diffuse)	0.000	0.972	0.028
C84.4 Peripheral T-cell lymphoma	0.000	0.972	0.028
K72.1 Chronic hepatic failure	0.028	0.972	0.000
C95 Leukaemia of unspecified cell type	0.000	0.972	0.027
C93 Monocytic leukaemia	0.000	0.973	0.027
C86 Other specified types of T/NK-cell lymphoma	0.000	0.973	0.027
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.974	0.026
S02.30 Fracture of orbital floor (closed)	0.026	0.974	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.974	0.026
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.974	0.026
C88.7 Other malignant immunoproliferative diseases	0.000	0.974	0.026
C88.3 Immunoproliferative small intestinal disease	0.000	0.974	0.026
C88.2 Gamma heavy chain disease	0.000	0.974	0.026
C88.1 Alpha heavy chain disease	0.000	0.974	0.026
K72.0 Acute and subacute hepatic failure	0.026	0.974	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.025	0.974	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.974	0.025
C81.0 Lymphocytic predominance	0.000	0.975	0.025
C91 Lymphoid leukaemia	0.000	0.975	0.025
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.975	0.025
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.975	0.025
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.975	0.025
C84.3 Lymphoepithelioid lymphoma	0.000	0.975	0.025
C84.2 T-zone lymphoma	0.000	0.975	0.025
C84.1 Sezary's diease	0.000	0.975	0.025
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.976	0.024
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.977	0.023
C84.5 Other and unspecified T-cell lymphomas	0.000	0.977	0.023
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.977	0.023
C81.2 Mixed cellularity	0.000	0.978	0.022
C94.7 Other specified leukaemias	0.000	0.978	0.022
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.978	0.022
C94.5 Acute myelofibrosis	0.000	0.978	0.022
C94.4 Acute panmyelosis	0.000	0.978	0.022
C94.3 Mast cell leukaemia	0.000	0.978	0.022
C94.2 Acute megakaryoblastic leukaemia	0.000	0.978	0.022
C94.1 Chronic erythraemia	0.000	0.978	0.022
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.978	0.022
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.978	0.022
C96.8 Histiocytic sarcoma	0.000	0.978	0.022
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.978	0.022
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.978	0.022
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.978	0.022
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.978	0.022
C96.3 True histiocytic lymphoma	0.000	0.978	0.022
C96.2 Malignant mast cell tumour	0.000	0.978	0.022
C96.1 Malignant histiocytosis	0.000	0.978	0.022
C96.0 Letterer-Siwe disease	0.000	0.978	0.022
C91.4 Hairy-cell leukaemia	0.000	0.978	0.022
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.978	0.022
C81.7 Other Hodgkin's disease	0.000	0.978	0.022
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.978	0.022
C81.3 Lymphocytic depletion	0.000	0.978	0.022
Z83.7 Family history of diseases of the digestive system	0.000	0.979	0.021
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.979	0.021
C81.9 Hodgkin's disease, unspecified	0.000	0.979	0.020
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.980	0.020
C95.7 Other leukaemia of unspecified cell type	0.000	0.980	0.020
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.980	0.020
C95.0 Acute leukaemia of unspecified cell type	0.000	0.980	0.020
C93.9 Monocytic leukaemia, unspecified	0.000	0.980	0.020
C93.7 Other monocytic leukaemia	0.000	0.980	0.020
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.980	0.020
C93.2 Subacute monocytic leukaemia	0.000	0.980	0.020
C93.0 Acute monocytic leukaemia	0.000	0.980	0.020
K72.9 Hepatic failure, unspecified	0.020	0.980	0.000
K75.0 Abscess of liver	0.019	0.980	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.980	0.020
C86.4 Blastic NK-cell lymphoma	0.000	0.980	0.020
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.980	0.020
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.980	0.020
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.980	0.020
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.980	0.020
C91.5 Adult T-cell leukaemia	0.000	0.980	0.020
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.981	0.019
C91.0 Acute lymphoblastic leukaemia	0.000	0.981	0.019
C81.1 Nodular sclerosis	0.000	0.981	0.018
N97.9 Female infertility, unspecified	0.018	0.982	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.982	0.018
C91.7 Other lymphoid leukaemia	0.000	0.982	0.018
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.982	0.018
C91.3 Prolymphocytic leukaemia	0.000	0.982	0.018
C91.2 Subacute lymphocytic leukaemia	0.000	0.982	0.018
S02.70 Multiple fractures involving skull and facial bones (closed)	0.016	0.983	0.001
C95.9 Leukaemia, unspecified	0.000	0.983	0.017
C93.1 Chronic monocytic leukaemia	0.000	0.983	0.016
C90.3 Solitary plasmacytoma	0.000	0.983	0.017
C90.1 Plasma cell leukaemia	0.000	0.984	0.016
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.984	0.016
C90.2 Plasmacytoma, extramedullary	0.000	0.984	0.016
A41 Other septicaemia	0.016	0.984	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.015	0.985	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.986	0.014
C91.9 Lymphoid leukaemia, unspecified	0.000	0.987	0.013
A41.4 Septicaemia due to anaerobes	0.013	0.987	0.000
D22 Melanocytic naevi	0.000	0.987	0.013
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.987	0.013
C92 Myeloid leukaemia	0.000	0.988	0.012
A41.3 Septicaemia due to Haemophilus influenzae	0.012	0.988	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.011	0.988	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.012	0.988	0.000
N97 Female infertility	0.011	0.989	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.989	0.011
C90.0 Multiple myeloma	0.000	0.989	0.011
D22.0 Melanocytic naevi of lip	0.000	0.990	0.010
N97.4 Female infertility associated with male factors	0.010	0.990	0.000
D22.9 Melanocytic naevi, unspecified	0.000	0.990	0.010
M79.80 Other specified soft tissue disorders (Multiple sites)	0.010	0.990	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.010	0.990	0.000
S00-S09 Injuries to the head	0.009	0.991	0.000
Z83 Family history of other specific disorders	0.000	0.991	0.009
N97.8 Female infertility of other origin	0.009	0.991	0.000
N97.0 Female infertility associated with anovulation	0.009	0.991	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.991	0.009
S06 Intracranial injury	0.009	0.991	0.000
C92.4 Acute promyelocytic leukaemia	0.000	0.991	0.009
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.991	0.009
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.991	0.009
C92.5 Acute myelomonocytic leukaemia	0.000	0.991	0.009
C92.3 Myeloid sarcoma	0.000	0.991	0.009
C92.2 Subacute myeloid leukaemia	0.000	0.991	0.009
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.009	0.991	0.000
S06.5 Traumatic subdural haemorrhage	0.009	0.991	0.000
N97.3 Female infertility of cervical origin	0.008	0.991	0.000
N97.2 Female infertility of uterine origin	0.008	0.991	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.992	0.008
S03 Dislocation, sprain and strain of joints and ligaments of head	0.008	0.992	0.000
O21.0 Mild hyperemesis gravidarum	0.008	0.992	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.992	0.008
S06.8 Other intracranial injuries	0.008	0.992	0.000
A41.8 Other specified septicaemia	0.008	0.992	0.000
S22.40 Multiple fractures of ribs (closed)	0.008	0.992	0.000
S06.4 Epidural haemorrhage	0.008	0.992	0.000
C92.7 Other myeloid leukaemia	0.000	0.992	0.007
S03.2 Dislocation of tooth	0.007	0.992	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.007	0.993	0.000
K81.1 Chronic cholecystitis	0.000	0.993	0.007
N97.1 Female infertility of tubal origin	0.007	0.993	0.000
S06.0 Concussion	0.007	0.993	0.000
S08 Traumatic amputation of part of head	0.007	0.993	0.000
S07 Crushing injury of head	0.007	0.993	0.000
S04 Injury of cranial nerves	0.007	0.993	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.993	0.007
S00 Superficial injury of head	0.007	0.993	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.993	0.007
Z83.6 Family history of diseases of the respiratory system	0.000	0.993	0.007
S06.40 Epidural haemorrhage (without open intracranial wound)	0.007	0.993	0.000
S00.7 Multiple superficial injuries of head	0.007	0.993	0.000
S06.7 Intracranial injury with prolonged coma	0.007	0.993	0.000
S06.1 Traumatic cerebral oedema	0.007	0.993	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
S03.1 Dislocation of septal cartilage of nose	0.006	0.994	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.006	0.994	0.000
S03.4 Sprain and strain of jaw	0.006	0.994	0.000
S03.3 Dislocation of other and unspecified parts of head	0.006	0.994	0.000
S03.0 Dislocation of jaw	0.006	0.994	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.994	0.006
S06.9 Intracranial injury, unspecified	0.006	0.994	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.006	0.994	0.000
S06.2 Diffuse brain injury	0.006	0.994	0.000
S00.4 Superficial injury of ear	0.006	0.994	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
S00.8 Superficial injury of other parts of head	0.006	0.994	0.000
S06.00 Concussion (without open intracranial wound)	0.006	0.994	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.006	0.994	0.000
S00.3 Superficial injury of nose	0.006	0.994	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.006	0.994	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.994	0.005
S00.1 Contusion of eyelid and periocular area	0.006	0.994	0.000
S06.01 Concussion (with open intracranial wound)	0.005	0.995	0.000
S04.9 Injury of unspecified cranial nerve	0.005	0.995	0.000
S04.8 Injury of other cranial nerves	0.005	0.995	0.000
S04.7 Injury of accessory nerve	0.005	0.995	0.000
S04.6 Injury of acoustic nerve	0.005	0.995	0.000
S04.5 Injury of facial nerve	0.005	0.995	0.000
S04.4 Injury of abducent nerve	0.005	0.995	0.000
S04.3 Injury of trigeminal nerve	0.005	0.995	0.000
S04.2 Injury of trochlear nerve	0.005	0.995	0.000
S04.1 Injury of oculomotor nerve	0.005	0.995	0.000
S04.0 Injury of optic nerve and pathways	0.005	0.995	0.000
S07.9 Crushing injury of head, part unspecified	0.005	0.995	0.000
S07.8 Crushing injury of other parts of head	0.005	0.995	0.000
S07.1 Crushing injury of skull	0.005	0.995	0.000
S07.0 Crushing injury of face	0.005	0.995	0.000
S08.9 Traumatic amputation of unspecified part of head	0.005	0.995	0.000
S08.8 Traumatic amputation of other parts of head	0.005	0.995	0.000
S08.1 Traumatic amputation of ear	0.005	0.995	0.000
S08.0 Avulsion of scalp	0.005	0.995	0.000
J46 Status asthmaticus	0.005	0.995	0.000
S22.4 Multiple fractures of ribs	0.005	0.995	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.005	0.995	0.000
S06.3 Focal brain injury	0.005	0.995	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.005	0.995	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.005	0.995	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.005	0.995	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.005	0.995	0.000
S00.0 Superficial injury of scalp	0.005	0.995	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.005	0.995	0.000
R74.8 Abnormal levels of other serum enzymes	0.005	0.995	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.005	0.995	0.000
Z63.5 Disruption of family by separation and divorce	0.005	0.995	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.004	0.995	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.004	0.995	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.996	0.004
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.004	0.996	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.996	0.004
S00.2 Other superficial injuries of eyelid and periocular area	0.004	0.996	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.996	0.004
L40.5 Arthropathic psoriasis	0.004	0.996	0.000
S22.41 Multiple fractures of ribs (open)	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.996	0.004
S06.31 Focal brain injury (with open intracranial wound)	0.004	0.996	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
S27.0 Traumatic pneumothorax	0.004	0.996	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.004	0.996	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.004	0.996	0.000
S09 Other and unspecified injuries of head	0.004	0.996	0.000
C92.0 Acute myeloid leukaemia	0.000	0.996	0.004
S06.20 Diffuse brain injury (without open intracranial wound)	0.004	0.996	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.004	0.996	0.000
Z63.8 Other specified problems related to primary support group	0.004	0.996	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.004	0.996	0.000
Z63 Other problems related to primary support group, including family circumstances	0.004	0.996	0.000
E61.1 Iron deficiency	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.996	0.004
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.996	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.003	0.997	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.003	0.997	0.000
S00.5 Superficial injury of lip and oral cavity	0.003	0.997	0.000
S52.6 Fracture of lower end of both ulna and radius	0.003	0.997	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.997	0.003
I84.3 External thrombosed haemorrhoids	0.003	0.997	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.003	0.997	0.000
S22.1 Multiple fractures of thoracic spine	0.003	0.997	0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.003	0.997	0.000
S27.8 Injury of other specified intrathoracic organs	0.003	0.997	0.000
S20-S29 Injuries to the thorax	0.003	0.997	0.000
S00.9 Superficial injury of head, part unspecified	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
S09.7 Multiple injuries of head	0.003	0.997	0.000
S09.2 Traumatic rupture of ear drum	0.003	0.997	0.000
S09.1 Injury of muscle and tendon of head	0.003	0.997	0.000
S20.0 Contusion of breast	0.003	0.997	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.003	0.997	0.000
B20.6 HIV disease resulting in Pneumocystis carinii pneumonia	0.003	0.997	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.003	0.997	0.000
Z63.9 Problem related to primary support group, unspecified	0.003	0.997	0.000
Z63.3 Absence of family member	0.003	0.997	0.000
Z63.2 Inadequate family support	0.003	0.997	0.000
Z63.1 Problems in relationship with parents and in-laws	0.003	0.997	0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.003	0.997	0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.003	0.997	0.000
S20.1 Other and unspecified superficial injuries of breast	0.003	0.997	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.997	0.003
I26 Pulmonary embolism	0.003	0.997	0.000
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
B23.8 HIV disease resulting in other specified conditions	0.003	0.997	0.000
S27.9 Injury of unspecified intrathoracic organ	0.003	0.997	0.000
S27.7 Multiple injuries of intrathoracic organs	0.003	0.997	0.000
S27.6 Injury of pleura	0.003	0.997	0.000
S27.5 Injury of thoracic trachea	0.003	0.997	0.000
S27.4 Injury of bronchus	0.003	0.997	0.000
C69.3 Choroid	0.000	0.997	0.003
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
S20.3 Other superficial injuries of front wall of thorax	0.003	0.997	0.000
S22.5 Flail chest	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
S27.2 Traumatic heamopneumothorax	0.003	0.997	0.000
S20.7 Multiple superficial injuries of thorax	0.002	0.997	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.997	0.000
B20.9 HIV disease resulting in unspecified infectious or parasitic disease	0.002	0.997	0.000
B20.8 HIV disease resulting in other infectious and parasitic diseases	0.002	0.997	0.000
B20.7 HIV disease resulting in multiple infections	0.002	0.997	0.000
B20.5 HIV disease resulting in other mycoses	0.002	0.997	0.000
B20.4 HIV disease resulting in candidiasis	0.002	0.997	0.000
B20.3 HIV disease resulting in other viral infections	0.002	0.997	0.000
B20.2 HIV disease resulting in cytomegaloviral disease	0.002	0.997	0.000
B20.1 HIV disease resulting in other bacterial infections	0.002	0.997	0.000
B20.0 HIV disease resulting in mycobacterial infection	0.002	0.997	0.000
Z63.6 Dependent relative needing care at home	0.002	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.002	0.997	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.002	0.997	0.000
B23.2 HIV disease resulting in haematological and immunological abnormalities, not elsewhere classified	0.002	0.997	0.000
B23.1 HIV disease resulting in (persistent) generalised lymphadenopathy	0.002	0.997	0.000
B23.0 Acute HIV infection syndrome	0.002	0.997	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.997	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.002	0.997	0.000
S26 Injury of heart	0.002	0.997	0.000
S25 Injury of blood vessels of thorax	0.002	0.997	0.000
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
R52.9 Pain, unspecified	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.000	0.998	0.002
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.002	0.998	0.000
S05 Injury of eye and orbit	0.002	0.998	0.000
S27.1 Traumatic haemothorax	0.002	0.998	0.000
S22.2 Fracture of sternum	0.002	0.998	0.000
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.002	0.998	0.000
B21.9 HIV disease resulting in unspecified malignant neoplasm	0.002	0.998	0.000
B21.8 HIV disease resulting in other malignant neoplasms	0.002	0.998	0.000
B21.7 HIV disease resulting in multiple malignant neoplasms	0.002	0.998	0.000
B21.3 HIV disease resulting in other malignant neoplasms of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
B21.2 HIV disease resulting in other types of non-Hodgkin's lymphoma	0.002	0.998	0.000
B21.1 HIV disease resulting in Burkitt's lymphoma	0.002	0.998	0.000
B21.0 HIV disease resulting in Kaposi's sarcoma	0.002	0.998	0.000
B22.7 HIV disease resulting in multiple diseases classified elsewhere	0.002	0.998	0.000
B22.2 HIV disease resulting in wasting syndrome	0.002	0.998	0.000
B22.1 HIV disease resulting in lymphoid interstitial pneumonitis	0.002	0.998	0.000
B22.0 HIV disease resulting in encephalopathy	0.002	0.998	0.000
S24 Injury of nerves and spinal cord at thorax level	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
S20.4 Other superficial injuries of back wall of thorax	0.002	0.998	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.998	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.998	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.998	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.998	0.002
S22.3 Fracture of rib	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.002	0.998	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
S22.51 Flail chest (open)	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
A30-A49 Other bacterial diseases	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
W07.0 Home	0.000	0.998	0.002
T02 Fractures involving multiple body regions	0.002	0.998	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.002	0.998	0.000
S25.8 Injury of other blood vessels of thorax	0.002	0.998	0.000
S25.7 Injury of multiple blood vessels of thorax	0.002	0.998	0.000
S25.5 Injury of intercostal blood vessels	0.002	0.998	0.000
S25.4 Injury of pulmonary blood vessels	0.002	0.998	0.000
S25.3 Injury of innominate or subclavian vein	0.002	0.998	0.000
S25.2 Injury of superior vena cava	0.002	0.998	0.000
S25.1 Injury of innominate or subclavian artery	0.002	0.998	0.000
S25.0 Injury of thoracic aorta	0.002	0.998	0.000
S26.9 Injury of heart, unspecified	0.002	0.998	0.000
S26.8 Other injuries of heart	0.002	0.998	0.000
S26.0 Injury of heart with haemopericardium	0.002	0.998	0.000
S28.1 Traumatic amputation of part of thorax	0.002	0.998	0.000
S28.0 Crushed chest	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.002	0.998	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
S52.20 Fracture of shaft of ulna (closed)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations