TreeWAS – Variant ID: rs7078012

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I64 Stroke, not specified as haemorrhage or infarction	0.185	0.815	0.000
I60-I69 Cerebrovascular diseases	0.178	0.822	0.000
I60 Subarachnoid haemorrhage	0.176	0.824	0.000
I67 Other cerebrovascular diseases	0.168	0.832	0.000
I61 Intracerebral haemorrhage	0.167	0.833	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.159	0.841	0.000
I67.2 Cerebral atherosclerosis	0.158	0.842	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.149	0.851	0.000
I60.8 Other subarachnoid haemorrhage	0.149	0.851	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.147	0.853	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.145	0.855	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.142	0.858	0.000
I67.1 Cerebral aneurysm, nonruptured	0.139	0.861	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.138	0.861	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.137	0.863	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.135	0.865	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.134	0.866	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.134	0.866	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.133	0.867	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.131	0.869	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.127	0.873	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.126	0.874	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.126	0.874	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.121	0.879	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.121	0.879	0.000
I67.5 Moyamoya disease	0.121	0.879	0.000
I67.4 Hypertensive encephalopathy	0.121	0.879	0.000
I67.3 Progressive vascular leukoencephalopathy	0.121	0.879	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.120	0.880	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.120	0.880	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.118	0.882	0.000
I67.9 Cerebrovascular disease, unspecified	0.116	0.884	0.000
I69 Sequelae of cerebrovascular disease	0.116	0.884	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.113	0.887	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.111	0.889	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.110	0.890	0.000
I61.8 Other intracerebral haemorrhage	0.106	0.893	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.103	0.897	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.102	0.898	0.000
I68.0 Cerebral amyloid angiopathy	0.097	0.903	0.000
I67.8 Other specified cerebrovascular diseases	0.097	0.903	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.096	0.904	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.096	0.904	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.096	0.904	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.096	0.904	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.096	0.904	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.096	0.904	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.094	0.906	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.094	0.906	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.094	0.906	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.087	0.913	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.085	0.915	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.084	0.916	0.000
I65.1 Occlusion and stenosis of basilar artery	0.082	0.918	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.077	0.923	0.000
I62 Other nontraumatic intracranial haemorrhage	0.076	0.924	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.074	0.926	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.074	0.926	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.074	0.926	0.000
I62.1 Nontraumatic extradural haemorrhage	0.055	0.945	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.043	0.957	0.000
I69.3 Sequelae of cerebral infarction	0.030	0.969	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.028	0.971	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.025	0.975	0.000
I65.2 Occlusion and stenosis of carotid artery	0.018	0.982	0.000
N20.1 Calculus of ureter	0.018	0.982	0.000
N20.0 Calculus of kidney	0.014	0.986	0.000
N20 Calculus of kidney and ureter	0.014	0.986	0.000
I73.0 Raynaud's syndrome	0.011	0.989	0.000
N20.2 Calculus of kidney with calculus of ureter	0.010	0.990	0.000
I63 Cerebral infarction	0.009	0.991	0.000
N20.9 Urinary calculus, unspecified	0.008	0.991	0.000
C18.0 Caecum	0.008	0.992	0.000
N28.8 Other specified disorders of kidney and ureter	0.008	0.992	0.000
N88.2 Stricture and stenosis of cervix uteri	0.007	0.993	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.007	0.993	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.007	0.993	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.007	0.993	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.007	0.993	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.007	0.993	0.000
Y40.8 Other systemic antibiotics	0.007	0.993	0.000
Y40 Systemic antibiotics	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
Y57 Other and unspecified drugs and medicaments	0.006	0.994	0.000
Y57.8 Other drugs and medicaments	0.006	0.994	0.000
Y43.3 Other antineoplastic drugs	0.006	0.994	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.006	0.994	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
Y43 Primarily systemic agents	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.006	0.994	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
C18 Malignant neoplasm of colon	0.006	0.994	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
C18.6 Descending colon	0.006	0.994	0.000
Y40.5 Aminoglycosides	0.006	0.994	0.000
Y58 Bacterial vaccines	0.006	0.994	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.994	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.005	0.994	0.000
C18.2 Ascending colon	0.006	0.994	0.000
Y54.3 Benzothiadiazine derivatives	0.005	0.995	0.000
I63.8 Other cerebral infarction	0.005	0.995	0.000
Y40.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
Y40.3 Macrolides	0.005	0.995	0.000
Y54.4 Loop [high-ceiling] diuretics	0.005	0.995	0.000
C18.1 Appendix	0.005	0.995	0.000
Y54.7 Agents affecting calcification	0.005	0.995	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.995	0.000
Y41.0 Sulphonamides	0.005	0.995	0.000
Y45.8 Other analgesics and antipyretics	0.005	0.995	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
Y54.5 Other diuretics	0.005	0.995	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.995	0.000
C18.5 Splenic flexure	0.005	0.995	0.000
Y45.2 Propionic acid derivatives	0.005	0.995	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
Y40.6 Rifamycins	0.005	0.995	0.000
Y40.4 Tetracyclines	0.005	0.995	0.000
Y40.2 Chloramphenicol group	0.005	0.995	0.000
Y41.5 Antiviral drugs	0.005	0.995	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
Y41.4 Anthelminthics	0.005	0.995	0.000
Y41.3 Other antiprotozoal drugs	0.005	0.995	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
Y41.1 Antimycobacterial drugs	0.005	0.995	0.000
Y54.9 Mineral salts, not elsewhere classified	0.005	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.005	0.995	0.000
Y54.0 Mineralocorticoids	0.005	0.995	0.000
Y57.7 Vitamins, not elsewhere classified	0.005	0.995	0.000
Y57.4 Pharmaceutical excipients	0.005	0.995	0.000
Y57.3 Alcohol deterrents	0.005	0.995	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
Y57.1 Lipotropic drugs	0.005	0.995	0.000
Y57.0 Appetite depressants [anorectics]	0.005	0.995	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
Y58.0 BCG vaccine	0.005	0.995	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.995	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.005	0.995	0.000
Y45.4 Antirheumatics	0.005	0.995	0.000
Y47.1 Benzodiazepines	0.005	0.995	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.004	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.995	0.000
Y43.2 Antineoplastic natural products	0.004	0.995	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.005	0.995	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.004	0.995	0.000
Y57.6 Other diagnostic agents	0.004	0.995	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.004	0.996	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y53.7 Emetics	0.004	0.996	0.000
Y53.6 Antidiarrhoeal drugs	0.004	0.996	0.000
Y53.5 Digestants	0.004	0.996	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.996	0.000
Y53.2 Stimulant laxatives	0.004	0.996	0.000
Y53.0 Histamine H2-receptor antagonists	0.004	0.996	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.004	0.996	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.996	0.004
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.996	0.000
Y53.4 Other laxatives	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
Y58.9 Other and unspecified bacterial vaccines	0.004	0.996	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.004	0.996	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.004	0.996	0.000
Y58.5 Diphtheria vaccine	0.004	0.996	0.000
Y58.4 Tetanus vaccine	0.004	0.996	0.000
Y58.3 Plague vaccine	0.004	0.996	0.000
Y58.2 Cholera vaccine	0.004	0.996	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.004	0.996	0.000
C18.8 Overlapping lesion of colon	0.004	0.996	0.000
Y40.0 Penicillins	0.004	0.996	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.996	0.000
Y47.4 Bromine compounds	0.004	0.996	0.000
Y47.3 Paraldehyde	0.004	0.996	0.000
Y47.2 Chloral derivatives	0.004	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
Y43.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
Y42.2 Antithyroid drugs	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.996	0.000
Y50.8 Other central nervous system stimulants	0.004	0.996	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.996	0.000
Y50.1 Opioid receptor antagonists	0.004	0.996	0.000
Y50.0 Analeptics	0.004	0.996	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Y55.5 Anticommon cold drugs	0.004	0.996	0.000
Y55.4 Expectorants	0.004	0.996	0.000
Y55.3 Antitussives	0.004	0.996	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
Y55.0 Oxytocic drugs	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
Y49.9 Psychotropic drug, unspecified	0.004	0.996	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
Y49.7 Psychostimulants with abuse potential	0.004	0.996	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.004	0.996	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
C18.4 Transverse colon	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
L57.0 Actinic keratosis	0.004	0.996	0.000
Y42.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
Y42.4 Oral contraceptives	0.004	0.996	0.000
Y42.1 Thyroid hormones and substitutes	0.004	0.996	0.000
Y48.5 Therapeutic gases	0.003	0.996	0.000
Y48.1 Parenteral anaesthetics	0.003	0.996	0.000
Y48.0 Inhaled anaesthetics	0.003	0.996	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.996	0.000
C22.0 Liver cell carcinoma	0.003	0.996	0.000
I73 Other peripheral vascular diseases	0.004	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.996	0.000
C18.3 Hepatic flexure	0.003	0.997	0.000
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.003	0.997	0.000
Y56.8 Other topical agents	0.003	0.997	0.000
Y56.7 Dental drugs, topically applied	0.003	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56.2 Local astringents and local detergents	0.003	0.997	0.000
Y56.1 Antipruritics	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.003	0.997	0.000
I71.0 Dissection of aorta [any part]	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
C22.9 Liver, unspecified	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.997	0.003
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.003	0.997	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.003	0.997	0.000
F25.1 Schizoaffective disorder, depressive type	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
M13.98 Arthritis, unspecified (Other)	0.000	0.997	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
C49.9 Connective and soft tissue, unspecified	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
I73.8 Other specified peripheral vascular diseases	0.003	0.997	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.997	0.000
F25 Schizoaffective disorders	0.003	0.997	0.000
F25.2 Schizoaffective disorder, mixed type	0.003	0.997	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.997	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.997	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.003	0.997	0.000
M13.9 Arthritis, unspecified	0.000	0.997	0.003
N28.0 Ischaemia and infarction of kidney	0.003	0.997	0.000
F29 Unspecified nonorganic psychosis	0.003	0.997	0.000
Z22.3 Carrier of other specified bacterial diseases	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.997	0.003
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.001
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
E14.9 Without complications	0.002	0.998	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
N20-N23 Urolithiasis	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
C22.7 Other specified carcinomas of liver	0.002	0.998	0.000
C22.4 Other sarcomas of liver	0.002	0.998	0.000
C22.3 Angiosarcoma of liver	0.002	0.998	0.000
C22.2 Hepatoblastoma	0.002	0.998	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.002	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M13.93 Arthritis, unspecified (Forearm)	0.000	0.998	0.002
W15.8 Other specified place	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
D12.7 Rectosigmoid junction	0.000	0.998	0.002
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
O82 Single delivery by Caesarean section	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
M13.0 Polyarthritis, unspecified	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.002	0.998	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.002	0.998	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.002	0.998	0.000
L57.5 Actinic granuloma	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.002	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.002	0.998	0.000
L57.1 Actinic reticuloid	0.002	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
N88 Other noninflammatory disorders of cervix uteri	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.002	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.002	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.002	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.002	0.998	0.000
W50-W64 Exposure to animate mechanical forces	0.002	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
M13 Other arthritis	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
W57.0 Home	0.002	0.998	0.000
W15 Fall from cliff	0.002	0.998	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.002	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
F20 Schizophrenia	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
W55 Bitten or struck by other mammals	0.002	0.998	0.000
M13.08 Polyarthritis, unspecified (Other)	0.000	0.998	0.002
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M13.06 Polyarthritis, unspecified (Lower leg)	0.000	0.998	0.002
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M13.04 Polyarthritis, unspecified (Hand)	0.000	0.998	0.002
M13.03 Polyarthritis, unspecified (Forearm)	0.000	0.998	0.002
M13.02 Polyarthritis, unspecified (Upper arm)	0.000	0.998	0.002
M13.01 Polyarthritis, unspecified (Shoulder region)	0.000	0.998	0.002
W51 Striking against or bumped into by another person	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T88.5 Other complications of anaesthesia	0.002	0.998	0.000
W15.9 Unspecified place	0.002	0.998	0.000
W55.8 Other specified place	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
X23.9 Unspecified place	0.002	0.998	0.000
R01.0 Benign and innocent cardiac murmurs	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
W51.9 Unspecified place	0.002	0.998	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.002	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
N88.4 Hypertrophic elongation of cervix uteri	0.002	0.998	0.000
N88.3 Incompetence of cervix uteri	0.002	0.998	0.000
N88.0 Leukoplakia of cervix uteri	0.002	0.998	0.000
W02.9 Unspecified place	0.002	0.998	0.000
W50.9 Unspecified place	0.002	0.998	0.000
N21 Calculus of lower urinary tract	0.002	0.998	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.001	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.001	0.998	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.001	0.998	0.000
W59 Bitten or crushed by other reptiles	0.001	0.998	0.000
W58 Bitten or struck by crocodile or alligator	0.001	0.998	0.000
W56 Contact with marine animal	0.001	0.998	0.000
W54 Bitten or struck by dog	0.001	0.998	0.000
W53 Bitten by rat	0.001	0.998	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.001	0.998	0.000
Z47 Other orthopaedic follow-up care	0.000	0.998	0.002
N21.1 Calculus in urethra	0.002	0.998	0.000
W50.0 Home	0.001	0.998	0.000
X23 Contact with hornets, wasps and bees	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.001	0.998	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.001	0.998	0.000
W55.7 Farm	0.001	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
W57.9 Unspecified place	0.001	0.998	0.000
W57.7 Farm	0.001	0.998	0.000
W57.6 Industrial and construction area	0.001	0.998	0.000
W57.5 Trade and service area	0.001	0.998	0.000
W57.4 Street and highway	0.001	0.998	0.000
W57.3 Sports and athletics area	0.001	0.998	0.000
W57.2 School, other institution and public administrative area	0.001	0.998	0.000
W57.1 Residential institution	0.001	0.998	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.002	0.998	0.000
M13.8 Other specified arthritis	0.000	0.998	0.001
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.001
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.001
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.001
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
W15.7 Farm	0.001	0.998	0.000
W15.6 Industrial and construction area	0.001	0.998	0.000
W15.5 Trade and service area	0.001	0.998	0.000
W15.4 Street and highway	0.001	0.998	0.000
W15.3 Sports and athletics area	0.001	0.998	0.000
W15.2 School, other institution and public administrative area	0.001	0.998	0.000
W15.1 Residential institution	0.001	0.998	0.000
W15.0 Home	0.001	0.998	0.000
W50.3 Sports and athletics area	0.001	0.998	0.000
W50.8 Other specified place	0.001	0.998	0.000
W50.7 Farm	0.001	0.998	0.000
W50.6 Industrial and construction area	0.001	0.998	0.000
W50.5 Trade and service area	0.001	0.998	0.000
W50.4 Street and highway	0.001	0.998	0.000
W50.2 School, other institution and public administrative area	0.001	0.998	0.000
W50.1 Residential institution	0.001	0.998	0.000
F20.8 Other schizophrenia	0.001	0.998	0.000
F20.6 Simple schizophrenia	0.001	0.998	0.000
F20.5 Residual schizophrenia	0.001	0.998	0.000
F20.4 Postschizophrenic depression	0.001	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.998	0.000
F20.2 Catatonic schizophrenia	0.001	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.998	0.000
N21.8 Other lower urinary tract calculus	0.001	0.998	0.000
T88.9 Complication of surgical and medical care, unspecified	0.001	0.998	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.001	0.998	0.000
T88.2 Shock due to anaesthesia	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations