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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7088203
log Bayes Factor = 22.7378
Chromosome 10   position 73,946,588  (GRCh37) Explore rs7088203 on Ensembl!
Variant rs7088203 is part of Cluster X0194

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
K22 Other diseases of oesophagus
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
K21 Gastro-oesophageal reflux disease
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.992 0.008 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.991 0.009 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
K20 Oesophagitis
0.984 0.016 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.983 0.017 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
K22.1 Ulcer of oesophagus
0.980 0.020 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.978 0.022 0.000
I80 Phlebitis and thrombophlebitis
0.974 0.026 0.000
K22.7 Barrett's oesophagus
0.969 0.031 0.000
E00-E07 Disorders of thyroid gland
0.967 0.033 0.000
I20-I25 Ischaemic heart diseases
0.962 0.038 0.000
Chapter I Certain infectious and parasitic diseases
0.961 0.039 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.960 0.040 0.000
M54 Dorsalgia
0.960 0.040 0.000
M45-M49 Spondylopathies
0.959 0.041 0.000
L82 Seborrhoeic keratosis
0.955 0.045 0.000
K26 Duodenal ulcer
0.948 0.052 0.000
E70-E90 Metabolic disorders
0.945 0.055 0.000
J30-J39 Other diseases of upper respiratory tract
0.943 0.057 0.000
T81 Complications of procedures, not elsewhere classified
0.941 0.059 0.000
I60-I69 Cerebrovascular diseases
0.937 0.063 0.000
I51 Complications and ill-defined descriptions of heart disease
0.936 0.064 0.000
Chapter VII Diseases of the eye and adnexa
0.932 0.068 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.931 0.069 0.000
I34 Nonrheumatic mitral valve disorders
0.929 0.071 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.927 0.073 0.000
E03 Other hypothyroidism
0.925 0.075 0.000
J95-J99 Other diseases of the respiratory system
0.921 0.079 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.920 0.080 0.000
M47 Spondylosis
0.920 0.080 0.000
M54.5 Low back pain
0.916 0.084 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.915 0.085 0.000
I35 Nonrheumatic aortic valve disorders
0.912 0.088 0.000
I46 Cardiac arrest
0.912 0.088 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.912 0.088 0.000
I84 Haemorrhoids
0.908 0.092 0.000
D60-D64 Aplastic and other anaemias
0.906 0.094 0.000
I21 Acute myocardial infarction
0.906 0.094 0.000
D50-D53 Nutritional anaemias
0.906 0.094 0.000
I49 Other cardiac arrhythmias
0.903 0.097 0.000
Chapter VIII Diseases of the ear and mastoid process
0.901 0.099 0.000
I42 Cardiomyopathy
0.897 0.103 0.000
I20 Angina pectoris
0.896 0.104 0.000
E03.9 Hypothyroidism, unspecified
0.895 0.105 0.000
B95-B98 Bacterial, viral and other infectious agents
0.894 0.106 0.000
E78.5 Hyperlipidaemia, unspecified
0.893 0.107 0.000
I50 Heart failure
0.892 0.108 0.000
J40-J47 Chronic lower respiratory diseases
0.890 0.110 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.887 0.113 0.000
I21.9 Acute myocardial infarction, unspecified
0.878 0.122 0.000
M47.8 Other spondylosis
0.876 0.124 0.000
E20-E35 Disorders of other endocrine glands
0.869 0.131 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.865 0.135 0.000
I47 Paroxysmal tachycardia
0.863 0.137 0.000
K31 Other diseases of stomach and duodenum
0.863 0.137 0.000
I95 Hypotension
0.863 0.137 0.000
E78.0 Pure hypercholesterolaemia
0.861 0.139 0.000
J32 Chronic sinusitis
0.860 0.140 0.000
I34.0 Mitral (valve) insufficiency
0.860 0.140 0.000
M54.2 Cervicalgia
0.860 0.140 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.858 0.142 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.858 0.142 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.854 0.146 0.000
J09-J18 Influenza and pneumonia
0.850 0.150 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.848 0.152 0.000
J98 Other respiratory disorders
0.847 0.153 0.000
I35.0 Aortic (valve) stenosis
0.844 0.156 0.000
I46.0 Cardiac arrest with successful resuscitation
0.843 0.157 0.000
H30-H36 Disorders of choroid and retina
0.843 0.157 0.000
I51.8 Other ill-defined heart diseases
0.842 0.158 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.841 0.159 0.000
E50-E64 Other nutritional deficiencies
0.840 0.160 0.000
I20.0 Unstable angina
0.835 0.165 0.000
K50-K52 Noninfective enteritis and colitis
0.833 0.167 0.000
R50-R69 General symptoms and signs
0.833 0.167 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.832 0.168 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.832 0.168 0.000
D51 Vitamin B12 deficiency anaemia
0.829 0.171 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.826 0.173 0.000
L91 Hypertrophic disorders of skin
0.823 0.177 0.000
M47.82 Other spondylosis (Cervical region)
0.823 0.177 0.000
I95.9 Hypotension, unspecified
0.820 0.180 0.000
K40-K46 Hernia
0.819 0.181 0.000
K22.2 Oesophageal obstruction
0.817 0.183 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.817 0.183 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.815 0.185 0.000
H43-H45 Disorders of vitreous body and globe
0.814 0.186 0.000
S20-S29 Injuries to the thorax
0.813 0.187 0.000
K26.7 Chronic without haemorrhage or perforation
0.812 0.188 0.000
K31.7 Polyp of stomach and duodenum
0.809 0.191 0.000
M50 Cervical disk disorders
0.807 0.193 0.000
J20-J22 Other acute lower respiratory infections
0.807 0.193 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.805 0.195 0.000
K22.0 Achalasia of cardia
0.804 0.196 0.000
Chapter XIV Diseases of the genitourinary system
0.803 0.197 0.000
K25 Gastric ulcer
0.803 0.197 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.802 0.198 0.000
D80-D89 Certain disorders involving the immune mechanism
0.800 0.200 0.000
A00-A09 Intestinal infectious diseases
0.799 0.201 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.797 0.203 0.000
H53-H54 Visual disturbances and blindness
0.796 0.204 0.000
M54.56 Low back pain (Lumbar region)
0.796 0.204 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.793 0.207 0.000
I69 Sequelae of cerebrovascular disease
0.793 0.207 0.000
D64 Other anaemias
0.792 0.208 0.000
I49.0 Ventricular fibrillation and flutter
0.789 0.211 0.000
M54.22 Cervicalgia (Cervical region)
0.788 0.212 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.787 0.213 0.000
H65-H75 Diseases of middle ear and mastoid
0.786 0.214 0.000
J45 Asthma
0.785 0.215 0.000
I50.1 Left ventricular failure
0.784 0.216 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.783 0.217 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
I84.2 Internal haemorrhoids without complication
0.781 0.219 0.000
I84.8 Unspecified haemorrhoids with other complications
0.780 0.220 0.000
L20-L30 Dermatitis and eczema
0.780 0.220 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.780 0.220 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.779 0.221 0.000
I05-I09 Chronic rheumatic heart diseases
0.778 0.222 0.000
L81 Other disorders of pigmentation
0.777 0.223 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.777 0.223 0.000
L50-L54 Urticaria and erythema
0.776 0.224 0.000
M40-M43 Deforming dorsopathies
0.776 0.224 0.000
I20.9 Angina pectoris, unspecified
0.776 0.224 0.000
L85 Other epidermal thickening
0.774 0.226 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.773 0.227 0.000
J34 Other disorders of nose and nasal sinuses
0.773 0.227 0.000
R59 Enlarged lymph nodes
0.773 0.227 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.772 0.228 0.000
S70-S79 Injuries to the hip and thigh
0.772 0.228 0.000
E07 Other disorders of thyroid
0.765 0.235 0.000
I42.2 Other hypertrophic cardiomyopathy
0.764 0.236 0.000
Chapter V Mental and behavioural disorders
0.763 0.236 0.000
K30 Dyspepsia
0.762 0.238 0.000
B35-B49 Mycoses
0.757 0.243 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
T90 Sequelae of injuries of head
0.756 0.244 0.000
I82 Other venous embolism and thrombosis
0.755 0.244 0.000
J00-J06 Acute upper respiratory infections
0.755 0.245 0.000
N17-N19 Renal failure
0.754 0.246 0.000
M20-M25 Other joint disorders
0.754 0.246 0.000
M54.59 Low back pain (Site unspecified)
0.754 0.246 0.000
I51.9 Heart disease, unspecified
0.753 0.247 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.753 0.247 0.000
R60 Oedema, not elsewhere classified
0.752 0.248 0.000
M47.9 Spondylosis, unspecified
0.751 0.249 0.000
I51.7 Cardiomegaly
0.751 0.249 0.000
M54.4 Lumbago with sciatica
0.749 0.250 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.749 0.251 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.749 0.251 0.000
M46 Other inflammatory spondylopathies
0.748 0.251 0.000
I84.6 Residual haemorrhoidal skin tags
0.747 0.253 0.000
M45 Ankylosing spondylitis
0.747 0.253 0.000
J30 Vasomotor and allergic rhinitis
0.746 0.254 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.745 0.255 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.745 0.255 0.000
S00-S09 Injuries to the head
0.744 0.256 0.000
I42.0 Dilated cardiomyopathy
0.744 0.256 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.744 0.256 0.000
K65-K67 Diseases of peritoneum
0.743 0.257 0.000
J98.1 Pulmonary collapse
0.742 0.258 0.000
J32.0 Chronic maxillary sinusitis
0.742 0.258 0.000
M51 Other intervertebral disk disorders
0.741 0.259 0.000
I35.9 Aortic valve disorder, unspecified
0.740 0.260 0.000
S90-S99 Injuries to the ankle and foot
0.740 0.260 0.000
I34.1 Mitral (valve) prolapse
0.739 0.261 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.737 0.263 0.000
S80-S89 Injuries to the knee and lower leg
0.737 0.263 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
K50 Crohn's disease [regional enteritis]
0.735 0.265 0.000
L90 Atrophic disorders of skin
0.735 0.265 0.000
I47.1 Supraventricular tachycardia
0.733 0.267 0.000
I21.4 Acute subendocardial myocardial infarction
0.732 0.267 0.000
S32 Fracture of lumbar spine and pelvis
0.731 0.269 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.731 0.269 0.000
I44 Atrioventricular and left bundle-branch block
0.730 0.270 0.000
A80-A89 Viral infections of the central nervous system
0.730 0.270 0.000
R47-R49 Symptoms and signs involving speech and voice
0.728 0.272 0.000
R21 Rash and other nonspecific skin eruption
0.728 0.272 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.728 0.272 0.000
M54.57 Low back pain (Lumbosacral region)
0.726 0.274 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.726 0.274 0.000
H10-H13 Disorders of conjunctiva
0.725 0.275 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.725 0.275 0.000
K26.4 Chronic or unspecified with haemorrhage
0.725 0.275 0.000
K22.4 Dyskinesia of oesophagus
0.724 0.276 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.724 0.276 0.000
L89 Decubitus ulcer
0.724 0.276 0.000
E06 Thyroiditis
0.724 0.276 0.000
N30-N39 Other diseases of urinary system
0.723 0.277 0.000
D62 Acute posthaemorrhagic anaemia
0.723 0.277 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.723 0.277 0.000
D50 Iron deficiency anaemia
0.723 0.277 0.000
R59.0 Localised enlarged lymph nodes
0.722 0.278 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.722 0.278 0.000
J47 Bronchiectasis
0.722 0.278 0.000
I38 Endocarditis, valve unspecified
0.722 0.278 0.000
I60 Subarachnoid haemorrhage
0.721 0.279 0.000
J39 Other diseases of upper respiratory tract
0.721 0.279 0.000
A04 Other bacterial intestinal infections
0.721 0.279 0.000
I86 Varicose veins of other sites
0.721 0.279 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.720 0.280 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.719 0.280 0.000
J60-J70 Lung diseases due to external agents
0.719 0.281 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
K22.9 Disease of oesophagus, unspecified
0.717 0.283 0.000
R94 Abnormal results of function studies
0.716 0.284 0.000
L84 Corns and callosities
0.716 0.284 0.000
L03 Cellulitis
0.716 0.284 0.000
M86-M90 Other osteopathies
0.716 0.284 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.716 0.284 0.000
K22.5 Diverticulum of oesophagus, acquired
0.716 0.284 0.000
K22.3 Perforation of oesophagus
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
S10-S19 Injuries to the neck
0.715 0.284 0.000
K44 Diaphragmatic hernia
0.715 0.285 0.000
E21.0 Primary hyperparathyroidism
0.715 0.285 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.715 0.285 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.714 0.286 0.000
Chapter VI Diseases of the nervous system
0.714 0.286 0.000
I50.9 Heart failure, unspecified
0.714 0.286 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.713 0.287 0.000
E40-E46 Malnutrition
0.713 0.287 0.000
L10-L14 Bullous disorders
0.713 0.287 0.000
K27 Peptic ulcer, site unspecified
0.713 0.287 0.000
H43 Disorders of vitreous body
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
I88 Nonspecific lymphadenitis
0.711 0.289 0.000
I87 Other disorders of veins
0.711 0.289 0.000
I81 Portal vein thrombosis
0.711 0.289 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.711 0.289 0.000
J84 Other interstitial pulmonary diseases
0.710 0.289 0.000
D64.9 Anaemia, unspecified
0.710 0.290 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.293 0.000
T86 Failure and rejection of transplanted organs and tissues
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
R60.0 Localised oedema
0.706 0.294 0.000
J45.9 Asthma, unspecified
0.706 0.294 0.000
K40 Inguinal hernia
0.705 0.295 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.705 0.295 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.705 0.295 0.000
L94 Other localised connective tissue disorders
0.705 0.295 0.000
L93 Lupus erythematosus
0.705 0.295 0.000
L87 Transepidermal elimination disorders
0.705 0.295 0.000
L88 Pyoderma gangrenosum
0.705 0.295 0.000
L86 Keratoderma in diseases classified elsewhere
0.705 0.295 0.000
L83 Acanthosis nigricans
0.705 0.295 0.000
L80 Vitiligo
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.704 0.295 0.000
I49.8 Other specified cardiac arrhythmias
0.704 0.296 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
J32.8 Other chronic sinusitis
0.703 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.701 0.298 0.000
I85 Oesophageal varices
0.701 0.299 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.701 0.299 0.000
H90-H95 Other disorders of ear
0.701 0.299 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.700 0.300 0.000
E53 Deficiency of other B group vitamins
0.700 0.300 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.698 0.301 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.698 0.301 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.698 0.301 0.000
S60-S69 Injuries to the wrist and hand
0.698 0.302 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.698 0.302 0.000
K70-K77 Diseases of liver
0.698 0.302 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.698 0.302 0.000
I69.3 Sequelae of cerebral infarction
0.697 0.303 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.696 0.304 0.000
I67 Other cerebrovascular diseases
0.696 0.304 0.000
M54.9 Dorsalgia, unspecified
0.696 0.304 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.695 0.305 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.693 0.307 0.000
E00 Congenital iodine-deficiency syndrome
0.693 0.307 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.693 0.307 0.000
I63 Cerebral infarction
0.692 0.307 0.000
N17 Acute renal failure
0.692 0.308 0.000
L40-L45 Papulosquamous disorders
0.691 0.308 0.000
M80-M85 Disorders of bone density and structure
0.691 0.309 0.000
H35 Other retinal disorders
0.691 0.309 0.000
I49.9 Cardiac arrhythmia, unspecified
0.691 0.309 0.000
I23 Certain current complications following acute myocardial infarction
0.689 0.310 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.689 0.311 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.689 0.311 0.000
B99-B99 Other infectious diseases
0.689 0.311 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.689 0.311 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.689 0.311 0.000
B65-B83 Helminthiases
0.689 0.311 0.000
B50-B64 Protozoal diseases
0.689 0.311 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.689 0.311 0.000
B15-B19 Viral hepatitis
0.689 0.311 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.689 0.311 0.000
A75-A79 Rickettsioses
0.689 0.311 0.000
A70-A74 Other diseases caused by chlamydiae
0.689 0.311 0.000
A65-A69 Other spirochaetal diseases
0.689 0.311 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.689 0.311 0.000
A20-A28 Certain zoonotic bacterial diseases
0.689 0.311 0.000
A15-A19 Tuberculosis
0.689 0.311 0.000
M54.8 Other dorsalgia
0.688 0.312 0.000
M54.6 Pain in thoracic spine
0.688 0.312 0.000
M54.1 Radiculopathy
0.688 0.312 0.000
M54.0 Panniculitis affecting regions of neck and back
0.688 0.312 0.000
B25-B34 Other viral diseases
0.688 0.312 0.000
M49 Spondylopathies in diseases classified elsewhere
0.687 0.312 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.687 0.312 0.000
I45 Other conduction disorders
0.686 0.314 0.000
L91.0 Keloid scar
0.686 0.314 0.000
M48 Other spondylopathies
0.685 0.315 0.000
R63 Symptoms and signs concerning food and fluid intake
0.685 0.315 0.000
J33 Nasal polyp
0.685 0.315 0.000
M50.0 Cervical disk disorder with myelopathy
0.685 0.315 0.000
H80-H83 Diseases of inner ear
0.684 0.316 0.000
I49.3 Ventricular premature depolarisation
0.683 0.317 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.683 0.317 0.000
L60-L75 Disorders of skin appendages
0.682 0.318 0.000
M47.89 Other spondylosis (Site unspecified)
0.681 0.319 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.681 0.319 0.000
H34 Retinal vascular occlusions
0.681 0.319 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.679 0.321 0.000
K26.5 Chronic or unspecified with perforation
0.679 0.321 0.000
K26.3 Acute without haemorrhage or perforation
0.679 0.321 0.000
K26.2 Acute with both haemorrhage and perforation
0.679 0.321 0.000
K26.1 Acute with perforation
0.679 0.321 0.000
K26.0 Acute with haemorrhage
0.679 0.321 0.000
I47.2 Ventricular tachycardia
0.679 0.321 0.000
L08 Other local infections of skin and subcutaneous tissue
0.678 0.322 0.000
E05.9 Thyrotoxicosis, unspecified
0.678 0.322 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.678 0.322 0.000
E88 Other metabolic disorders
0.678 0.322 0.000
E85 Amyloidosis
0.678 0.322 0.000
E84 Cystic fibrosis
0.678 0.322 0.000
E79 Disorders of purine and pyrimidine metabolism
0.678 0.322 0.000
E77 Disorders of glycoprotein metabolism
0.678 0.322 0.000
E76 Disorders of glycosaminoglycan metabolism
0.678 0.322 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.678 0.322 0.000
E74 Other disorders of carbohydrate metabolism
0.678 0.322 0.000
E73 Lactose intolerance
0.678 0.322 0.000
E72 Other disorders of amino-acid metabolism
0.678 0.322 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.678 0.322 0.000
E70 Disorders of aromatic amino-acid metabolism
0.678 0.322 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.678 0.322 0.000
R61 Hyperhidrosis
0.678 0.322 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.677 0.323 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.677 0.323 0.000
I46.9 Cardiac arrest, unspecified
0.676 0.324 0.000
J37 Chronic laryngitis and laryngotracheitis
0.676 0.324 0.000
T81.9 Unspecified complication of procedure
0.675 0.325 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.675 0.325 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.675 0.325 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.675 0.325 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.675 0.325 0.000
J36 Peritonsillar abscess
0.674 0.325 0.000
H36 Retinal disorders in diseases classified elsewhere
0.674 0.326 0.000
J90-J94 Other diseases of pleura
0.673 0.327 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.673 0.327 0.000
R26 Abnormalities of gait and mobility
0.673 0.327 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.672 0.328 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.672 0.328 0.000
I62 Other nontraumatic intracranial haemorrhage
0.672 0.328 0.000
K35-K38 Diseases of appendix
0.672 0.328 0.000
N00-N08 Glomerular diseases
0.672 0.328 0.000
I51.6 Cardiovascular disease, unspecified
0.671 0.329 0.000
I51.5 Myocardial degeneration
0.671 0.329 0.000
I51.4 Myocarditis, unspecified
0.671 0.329 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.671 0.329 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.671 0.329 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.671 0.329 0.000
I51.0 Cardiac septal defect, acquired
0.671 0.329 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.671 0.329 0.000
K29 Gastritis and duodenitis
0.671 0.329 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.671 0.329 0.000
J18 Pneumonia, organism unspecified
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.669 0.331 0.000
R00 Abnormalities of heart beat
0.669 0.331 0.000
J22 Unspecified acute lower respiratory infection
0.669 0.331 0.000
J32.9 Chronic sinusitis, unspecified
0.669 0.331 0.000
D86 Sarcoidosis
0.668 0.332 0.000
H55-H59 Other disorders of eye and adnexa
0.668 0.332 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.668 0.332 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.668 0.332 0.000
E78.8 Other disorders of lipoprotein metabolism
0.668 0.332 0.000
E78.6 Lipoprotein deficiency
0.668 0.332 0.000
E78.4 Other hyperlipidaemia
0.668 0.332 0.000
E78.3 Hyperchylomicronaemia
0.668 0.332 0.000
E78.2 Mixed hyperlipidaemia
0.668 0.332 0.000
E78.1 Pure hyperglyceridaemia
0.668 0.332 0.000
H60-H62 Diseases of external ear
0.668 0.332 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.666 0.334 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.666 0.334 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.666 0.334 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.666 0.334 0.000
M70-M79 Other soft tissue disorders
0.665 0.335 0.000
M65-M68 Disorders of synovium and tendon
0.664 0.336 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.663 0.336 0.000
E03.8 Other specified hypothyroidism
0.663 0.337 0.000
E03.5 Myxoedema coma
0.663 0.337 0.000
E03.4 Atrophy of thyroid (acquired)
0.663 0.337 0.000
E03.3 Postinfectious hypothyroidism
0.663 0.337 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.663 0.337 0.000
E03.1 Congenital hypothyroidism without goitre
0.663 0.337 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.663 0.337 0.000
I42.9 Cardiomyopathy, unspecified
0.663 0.337 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.662 0.338 0.000
J96 Respiratory failure, not elsewhere classified
0.660 0.340 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.660 0.340 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.659 0.340 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.659 0.340 0.000
I99 Other and unspecified disorders of circulatory system
0.659 0.340 0.000
M47.2 Other spondylosis with radiculopathy
0.659 0.341 0.000
M47.1 Other spondylosis with myelopathy
0.659 0.341 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.659 0.341 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.659 0.341 0.000
I84.3 External thrombosed haemorrhoids
0.659 0.341 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.658 0.342 0.000
R03.1 Nonspecific low blood-pressure reading
0.658 0.342 0.000
M54.55 Low back pain (Thoracolumbar region)
0.657 0.343 0.000
M54.54 Low back pain-Thoracic
0.657 0.343 0.000
M54.53 Low back pain-Cervicothoracic
0.657 0.343 0.000
M54.52 Low back pain-Cervical
0.657 0.343 0.000
M54.51 Low back pain-Occipit-atl-axl
0.657 0.343 0.000
M54.50 Low back pain (Multiple sites in spine)
0.657 0.343 0.000
D50.9 Iron deficiency anaemia, unspecified
0.657 0.343 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.656 0.344 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.656 0.344 0.000
K83 Other diseases of biliary tract
0.654 0.346 0.000
I35.8 Other aortic valve disorders
0.654 0.346 0.000
I46.1 Sudden cardiac death, so described
0.654 0.346 0.000
I27 Other pulmonary heart diseases
0.654 0.346 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.654 0.346 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.654 0.346 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.654 0.346 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.654 0.346 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.654 0.346 0.000
T83.2 Mechanical complication of graft of urinary organ
0.654 0.346 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.654 0.346 0.000
M54.3 Sciatica
0.653 0.347 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.653 0.347 0.000
H54 Blindness and low vision
0.653 0.347 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.652 0.348 0.000
I61 Intracerebral haemorrhage
0.652 0.348 0.000
I84.0 Internal thrombosed haemorrhoids
0.651 0.349 0.000
I84.1 Internal haemorrhoids with other complications
0.651 0.349 0.000
T93 Sequelae of injuries of lower limb
0.651 0.349 0.000
J98.4 Other disorders of lung
0.650 0.350 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.650 0.350 0.000
D61 Other aplastic anaemias
0.650 0.350 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.650 0.350 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.650 0.350 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.650 0.350 0.000
D53 Other nutritional anaemias
0.649 0.351 0.000
D52 Folate deficiency anaemia
0.649 0.351 0.000
R11 Nausea and vomiting
0.649 0.351 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.649 0.351 0.000
Q80-Q89 Other congenital malformations
0.649 0.351 0.000
N18 Chronic renal failure
0.648 0.352 0.000
I49.4 Other and unspecified premature depolarisation
0.647 0.353 0.000
I49.2 Junctional premature depolarisation
0.647 0.353 0.000
I49.1 Atrial premature depolarisation
0.647 0.353 0.000
J43 Emphysema
0.647 0.353 0.000
N17.9 Acute renal failure, unspecified
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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