TreeWAS – Variant ID: rs7090512

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.999	0.001	0.000
E03 Other hypothyroidism	0.936	0.064	0.000
E00-E07 Disorders of thyroid gland	0.865	0.135	0.000
E04 Other non-toxic goitre	0.830	0.170	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.828	0.172	0.000
E04.2 Non-toxic multinodular goitre	0.828	0.172	0.000
E05.9 Thyrotoxicosis, unspecified	0.765	0.235	0.000
E03.8 Other specified hypothyroidism	0.748	0.252	0.000
E03.1 Congenital hypothyroidism without goitre	0.730	0.270	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.696	0.304	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.690	0.310	0.000
E03.5 Myxoedema coma	0.671	0.329	0.000
E03.4 Atrophy of thyroid (acquired)	0.671	0.329	0.000
E03.3 Postinfectious hypothyroidism	0.671	0.329	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.630	0.370	0.000
E05.8 Other thyrotoxicosis	0.625	0.375	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.620	0.380	0.000
E00 Congenital iodine-deficiency syndrome	0.620	0.380	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.606	0.394	0.000
E04.8 Other specified non-toxic goitre	0.595	0.405	0.000
E05.5 Thyroid crisis or storm	0.594	0.406	0.000
E05.4 Thyrotoxicosis factitia	0.594	0.406	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.594	0.406	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.593	0.407	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.592	0.407	0.000
E06 Thyroiditis	0.548	0.451	0.000
E04.1 Non-toxic single thyroid nodule	0.527	0.473	0.000
E04.0 Non-toxic diffuse goitre	0.460	0.540	0.000
E06.3 Autoimmune thyroiditis	0.447	0.552	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.445	0.555	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.445	0.555	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.445	0.555	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.445	0.555	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.445	0.555	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.445	0.555	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.445	0.555	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.445	0.555	0.000
E06.5 Other chronic thyroiditis	0.405	0.595	0.000
E06.4 Drug-induced thyroiditis	0.393	0.607	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.393	0.607	0.000
E06.0 Acute thyroiditis	0.393	0.607	0.000
E07 Other disorders of thyroid	0.388	0.612	0.000
E06.1 Subacute thyroiditis	0.337	0.662	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.666	0.334
C79 Secondary malignant neoplasm of other sites	0.000	0.668	0.332
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.670	0.330
C79.6 Secondary malignant neoplasm of ovary	0.000	0.680	0.320
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.701	0.299
E07.1 Dyshormogenetic goitre	0.278	0.721	0.000
E07.0 Hypersecretion of calcitonin	0.278	0.721	0.000
E06.9 Thyroiditis, unspecified	0.272	0.728	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.753	0.247
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.762	0.238
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.770	0.230
E07.8 Other specified disorders of thyroid	0.220	0.779	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.780	0.220
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.802	0.198
E04.9 Non-toxic goitre, unspecified	0.193	0.807	0.000
E07.9 Disorder of thyroid, unspecified	0.164	0.836	0.000
A49.0 Staphylococcal infection, unspecified	0.072	0.928	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.943	0.057
C79.9 Secondary malignant neoplasm, unspecified site	0.001	0.945	0.054
C78.0 Secondary malignant neoplasm of lung	0.000	0.951	0.049
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.952	0.048
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.959	0.041
Q61.3 Polycystic kidney, unspecified	0.040	0.960	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.961	0.039
C78.2 Secondary malignant neoplasm of pleura	0.000	0.962	0.038
Q61 Cystic kidney disease	0.037	0.963	0.000
Q61.2 Polycystic kidney, adult type	0.037	0.963	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.968	0.032
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.969	0.031
Q61.0 Congenital single renal cyst	0.031	0.969	0.000
C80 Malignant neoplasm without specification of site	0.000	0.969	0.031
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.969	0.031
C76.3 Pelvis	0.000	0.969	0.030
Q61.9 Cystic kidney disease, unspecified	0.029	0.971	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.972	0.028
C76.7 Other ill-defined sites	0.000	0.972	0.028
C76.5 Lower limb	0.000	0.972	0.028
C76.4 Upper limb	0.000	0.972	0.028
C76.2 Abdomen	0.000	0.972	0.028
C76.1 Thorax	0.000	0.972	0.028
Q61.5 Medullary cystic kidney	0.027	0.973	0.000
Q61.8 Other cystic kidney diseases	0.027	0.973	0.000
Q61.1 Polycystic kidney, infantile type	0.027	0.973	0.000
Q61.4 Renal dysplasia	0.027	0.973	0.000
C76.0 Head, face and neck	0.000	0.976	0.024
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.977	0.023
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.978	0.022
D63.8 Anaemia in other chronic diseases classified elsewhere	0.021	0.979	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.980	0.020
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.980	0.020
A49 Bacterial infection of unspecified site	0.019	0.981	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.018	0.982	0.000
T88.4 Failed or difficult intubation	0.017	0.983	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.983	0.017
A49.1 Streptococcal infection, unspecified	0.016	0.984	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.015	0.985	0.000
E40-E46 Malnutrition	0.015	0.985	0.000
A49.3 Mycoplasma infection, unspecified	0.013	0.986	0.000
E10-E14 Diabetes mellitus	0.013	0.987	0.000
E46 Unspecified protein-energy malnutrition	0.012	0.988	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.012	0.988	0.000
E10 Insulin-dependent diabetes mellitus	0.012	0.988	0.000
E10.9 Without complications	0.012	0.988	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.011	0.989	0.000
E14 Unspecified diabetes mellitus	0.011	0.989	0.000
E10.3 With ophthalmic complications	0.011	0.989	0.000
E14.3 With ophthalmic complications	0.011	0.989	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.011	0.989	0.000
E45 Retarded development following protein-energy malnutrition	0.011	0.989	0.000
E43 Unspecified severe protein-energy malnutrition	0.011	0.989	0.000
E42 Marasmic kwashiorkor	0.011	0.989	0.000
E41 Nutritional marasmus	0.011	0.989	0.000
E40 Kwashiorkor	0.011	0.989	0.000
E14.9 Without complications	0.010	0.990	0.000
E12 Malnutrition-related diabetes mellitus	0.009	0.990	0.000
D63.0 Anaemia in neoplastic disease	0.009	0.991	0.000
E10.4 With neurological complications	0.009	0.991	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.991	0.009
Z02.8 Other examinations for administrative purposes	0.009	0.991	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.009	0.991	0.000
E10.7 With multiple complications	0.009	0.991	0.000
E10.8 With unspecified complications	0.009	0.991	0.000
E10.1 With ketoacidosis	0.009	0.991	0.000
E10.6 With other specified complications	0.009	0.991	0.000
E14.5 With peripheral circulatory complications	0.009	0.991	0.000
E15 Nondiabetic hypoglycaemic coma	0.008	0.992	0.000
E14.7 With multiple complications	0.008	0.992	0.000
E10.2 With renal complications	0.008	0.992	0.000
E10.0 With coma	0.008	0.992	0.000
E14.8 With unspecified complications	0.008	0.992	0.000
U80.1 Methicillin resistant agent	0.000	0.992	0.008
E44.1 Mild protein-energy malnutrition	0.008	0.992	0.000
E44.0 Moderate protein-energy malnutrition	0.008	0.992	0.000
I49.9 Cardiac arrhythmia, unspecified	0.008	0.992	0.000
Q60-Q64 Congenital malformations of the urinary system	0.008	0.992	0.000
E14.2 Withrenal complications	0.007	0.992	0.000
E14.1 With ketoacidosis	0.007	0.992	0.000
E65-E68 Obesity and other hyperalimentation	0.007	0.993	0.000
E14.0 With coma	0.007	0.993	0.000
A49.8 Other bacterial infections of unspecified site	0.007	0.993	0.000
A49.9 Bacterial infection, unspecified	0.007	0.993	0.000
E14.6 With other specified complications	0.007	0.993	0.000
E14.4 With neurological complications	0.007	0.993	0.000
E12.9 Without complications	0.007	0.993	0.000
E12.8 With unspecified complications	0.007	0.993	0.000
E12.7 With multiple complications	0.007	0.993	0.000
E12.6 With other specified complications	0.007	0.993	0.000
E12.5 With peripheral circulatory complications	0.007	0.993	0.000
E12.4 With neurological complications	0.007	0.993	0.000
E12.3 With ophthalmic complications	0.007	0.993	0.000
E12.2 With renal complications	0.007	0.993	0.000
E12.1 With ketoacidosis	0.007	0.993	0.000
E12.0 With coma	0.007	0.993	0.000
E13 Other specified diabetes mellitus	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.007	0.993	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.007	0.993	0.000
E10.5 With peripheral circulatory complications	0.007	0.993	0.000
E50-E64 Other nutritional deficiencies	0.007	0.993	0.000
E16 Other disorders of pancreatic internal secretion	0.006	0.993	0.000
E29 Testicular dysfunction	0.006	0.994	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.006	0.994	0.000
E20-E35 Disorders of other endocrine glands	0.006	0.994	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.006	0.994	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.006	0.994	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.006	0.994	0.000
E67 Other hyperalimentation	0.005	0.994	0.000
E68 Sequelae of hyperalimentation	0.005	0.994	0.000
B07 Viral warts	0.005	0.995	0.000
E54 Ascorbic acid deficiency	0.005	0.995	0.000
E13.8 With unspecified complications	0.005	0.995	0.000
E13.7 With multiple complications	0.005	0.995	0.000
E13.6 With other specified complications	0.005	0.995	0.000
E13.5 With peripheral circulatory complications	0.005	0.995	0.000
E13.4 With neurological complications	0.005	0.995	0.000
E13.2 With renal complications	0.005	0.995	0.000
E13.1 With ketoacidosis	0.005	0.995	0.000
E13.0 With coma	0.005	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.005	0.995	0.000
Z87.0 Personal history of diseases of the respiratory system	0.005	0.995	0.000
K90.0 Coeliac disease	0.005	0.995	0.000
E13.3 With ophthalmic complications	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.005	0.995	0.000
E50 Vitamin A deficiency	0.005	0.995	0.000
E60 Dietary zinc deficiency	0.005	0.995	0.000
E59 Dietary selenium deficiency	0.005	0.995	0.000
E52 Niacin deficiency [pellagra]	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.005	0.995	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.005	0.995	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.005	0.995	0.000
E51 Thiamine deficiency	0.005	0.995	0.000
E34 Other endocrine disorders	0.005	0.995	0.000
D51 Vitamin B12 deficiency anaemia	0.005	0.995	0.000
E56 Other vitamin deficiencies	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.005	0.995	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.005	0.995	0.000
E16.4 Abnormal secretion of gastrin	0.005	0.995	0.000
E16.3 Increased secretion of glucagon	0.005	0.995	0.000
E63 Other nutritional deficiencies	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
H50.1 Divergent concomitant strabismus	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.005	0.995	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.995	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
L28.0 Lichen simplex chronicus	0.005	0.995	0.000
E65 Localised adiposity	0.004	0.995	0.000
E27 Other disorders of adrenal gland	0.004	0.995	0.000
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
E16.1 Other hypoglycaemia	0.004	0.996	0.000
H50.5 Heterophoria	0.004	0.996	0.000
E67.8 Other specified hyperalimentation	0.004	0.996	0.000
E67.3 Hypervitaminosis D	0.004	0.996	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.996	0.000
E67.1 Hypercarotenaemia	0.004	0.996	0.000
E67.0 Hypervitaminosis A	0.004	0.996	0.000
H50.0 Convergent concomitant strabismus	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.004	0.996	0.000
E61 Deficiency of other nutrient elements	0.004	0.996	0.000
D60-D64 Aplastic and other anaemias	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
Q64.4 Malformation of urachus	0.004	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
Q63.2 Ectopic kidney	0.004	0.996	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.996	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.996	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.996	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.996	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.996	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.996	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.996	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.996	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.996	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.996	0.000
E64.3 Sequelae of rickets	0.004	0.996	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.996	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.996	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.996	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.004	0.996	0.000
Q64.8 Other specified congenital malformations of urinary system	0.004	0.996	0.000
Q64.6 Congenital diverticulum of bladder	0.004	0.996	0.000
Q64.5 Congenital absence of bladder and urethra	0.004	0.996	0.000
Q64.2 Congenital posterior urethral valves	0.004	0.996	0.000
Q64.1 Exstrophy of urinary bladder	0.004	0.996	0.000
Q64.0 Epispadias	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
H50 Other strabismus	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
E34.0 Carcinoid syndrome	0.004	0.996	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.004	0.996	0.000
E51.9 Thiamine deficiency, unspecified	0.004	0.996	0.000
E51.8 Other manifestations of thiamine deficiency	0.004	0.996	0.000
E51.1 Beriberi	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.004	0.996	0.000
E34.4 Constitutional tall stature	0.004	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.996	0.000
Z02 Examination and encounter for administrative purposes	0.004	0.996	0.000
D51.2 Transcobalamin II deficiency	0.004	0.996	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.004	0.996	0.000
E56.9 Vitamin deficiency, unspecified	0.004	0.996	0.000
E56.8 Deficiency of other vitamins	0.004	0.996	0.000
E56.0 Deficiency of vitamin E	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
K60.3 Anal fistula	0.000	0.996	0.004
E63.8 Other specified nutritional deficiencies	0.004	0.996	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.996	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
E53 Deficiency of other B group vitamins	0.004	0.996	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.000	0.996	0.004
E26.8 Other hyperaldosteronism	0.004	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.996	0.000
E30.8 Other disorders of puberty	0.003	0.996	0.000
E30.1 Precocious puberty	0.003	0.996	0.000
E30.0 Delayed puberty	0.003	0.996	0.000
E32.9 Disease of thymus, unspecified	0.003	0.996	0.000
E32.8 Other diseases of thymus	0.003	0.996	0.000
E32.1 Abscess of thymus	0.003	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.996	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.003	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.996	0.000
E25.8 Other adrenogenital disorders	0.003	0.996	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.996	0.000
E31.8 Other polyglandular dysfunction	0.003	0.996	0.000
E31.1 Polyglandular hyperfunction	0.003	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.996	0.000
E27.2 Addisonian crisis	0.004	0.996	0.000
E56.1 Deficiency of vitamin K	0.003	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.996	0.000
E34.8 Other specified endocrine disorders	0.003	0.996	0.000
D61 Other aplastic anaemias	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.003	0.996	0.000
E63.9 Nutritional deficiency, unspecified	0.003	0.996	0.000
E22 Hyperfunction of pituitary gland	0.003	0.996	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.996	0.000
E27.0 Other adrenocortical overactivity	0.003	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.997	0.003
D61.1 Drug-induced aplastic anaemia	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
H50.3 Intermittent heterotropia	0.003	0.997	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.997	0.003
N99.4 Postprocedural pelvic peritoneal adhesions	0.003	0.997	0.000
S83.7 Injury to multiple structures of knee	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
H50.9 Strabismus, unspecified	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.003	0.997	0.000
H50.6 Mechanical strabismus	0.003	0.997	0.000
S83.1 Dislocation of knee	0.000	0.997	0.003
S83.0 Dislocation of patella	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
E13.9 Without complications	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
Z02.9 Examination for administrative purposes, unspecified	0.003	0.997	0.000
Z02.7 Issue of medical certificate	0.003	0.997	0.000
Z02.6 Examination for insurance purposes	0.003	0.997	0.000
Z02.5 Examination for participation in sport	0.003	0.997	0.000
Z02.4 Examination for driving licence	0.003	0.997	0.000
Z02.3 Examination for recruitment to armed forces	0.003	0.997	0.000
Z02.2 Examination for admission to residential institution	0.003	0.997	0.000
Z02.1 Pre-employment examination	0.003	0.997	0.000
Z02.0 Examination for admission to educational institution	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.003	0.997	0.000
E55.0 Rickets, active	0.003	0.997	0.000
N99.1 Postprocedural urethral stricture	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
D61.8 Other specified aplastic anaemias	0.003	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.997	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.997	0.003
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.000	0.997	0.003
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
H50.8 Other specified strabismus	0.002	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.003	0.997	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
Z74.0 Reduced mobility	0.003	0.997	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.003	0.997	0.000
I49.3 Ventricular premature depolarisation	0.003	0.997	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
D22.1 Melanocytic naevi of eyelid, including canthus	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
L28 Lichen simplex chronicus and prurigo	0.002	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.997	0.000
K90 Intestinal malabsorption	0.003	0.997	0.000
E61.1 Iron deficiency	0.002	0.997	0.000
H50.4 Other and unspecified heterotropia	0.002	0.997	0.000
D52 Folate deficiency anaemia	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
H34.2 Other retinal artery occlusions	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
E66 Obesity	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
K90.8 Other intestinal malabsorption	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.000	0.998	0.002
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
I49.1 Atrial premature depolarisation	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
L28.1 Prurigo nodularis	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.000	0.998	0.002
K90.3 Pancreatic steatorrhoea	0.002	0.998	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.002	0.998	0.000
K90.1 Tropical sprue	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations